Wei, Lu

Combined from CaltechAUTHORS

• Qian, Naixin and Xiong, Hanqing, el al. (2025) Merging Vibrational Spectroscopy with Fluorescence Microscopy: Combining the Best of Two Worlds; Annual Review of Physical Chemistry; Vol. 76; 279-301; 10.1146/annurev-physchem-082423-121033
• Lee, Dongkwan and Wang, Haomin, el al. (2025) Wide-field bond-selective fluorescence imaging: from single-molecule to cellular imaging beyond video rate; Optica; Vol. 12; No. 2; 148; 10.1364/optica.545195
• Kocheril, Philip A. and Wang, Haomin, el al. (2024) Nitrile Vibrational Lifetimes as Probes of Local Electric Fields; Journal of Physical Chemistry Letters; Vol. 15; No. 9; 5306-5314; 10.1021/acs.jpclett.4c00597
• Qian, Chenxi and Liu, Hanwei, el al. (2024) Quantitative Real-Time Analysis of Living Materials by Stimulated Raman Scattering Microscopy; Analytical Chemistry; Vol. 96; No. 17; 6540–6549
• Chadha, Rahuljeet S. and Guerrero, Jason A., el al. (2024) Seeing is Believing: Developing Multimodal Metabolic Insights at the Molecular Level; ACS Central Science; Vol. 10; No. 4; 758-774; PMCID PMC11046475; 10.1021/acscentsci.3c01438
• Wang, Haomin and Lee, Dongkwan, el al. (2023) Bond-selective fluorescence imaging with single-molecule sensitivity; Nature Photonics; Vol. 17; No. 10; 846-855; PMCID PMC10756635; 10.1038/s41566-023-01243-8
• Shen, Yihui and Wei, Lu, el al. (2023) Raman Imaging Reveals Insights into Membrane Phase Biophysics in Cells; Journal of Physical Chemistry B; Vol. 127; No. 28; 6233-6240; PMCID PMC11209838; 10.1021/acs.jpcb.3c03125
• Du, Jiajun and Tao, Xuecheng, el al. (2023) Computational Design of Molecular Probes for Electronic Preresonance Raman Scattering Microscopy; Journal of Physical Chemistry B; Vol. 127; No. 22; 4979-4988; PMCID PMC10676804; 10.1021/acs.jpcb.3c00699
• Wang, Haomin and Lee, Dongkwan, el al. (2023) Toward the Next Frontiers of Vibrational Bioimaging; Chemical and Biomedical Imaging; Vol. 1; No. 1; 3-17; PMCID PMC10131268; 10.1021/cbmi.3c00004
• Du, Jiajun and Wang, Haomin, el al. (2022) Bringing Vibrational Imaging to Chemical Biology with Molecular Probes; ACS Chemical Biology; Vol. 17; No. 7; 1621-1637; PMCID PMC10676805; 10.1021/acschembio.2c00200
• Bi, Xiaotian and Miao, Kun, el al. (2022) Alkyne-Tagged Raman Probes for Local Environmental Sensing by Hydrogen–Deuterium Exchange; Journal of the American Chemical Society; Vol. 144; No. 19; 8504-8514; 10.1021/jacs.2c01991
• Miao, Kun and Lin, Li-En, el al. (2022) Label-free Super-resolution Imaging Enabled by Vibrational Imaging of Swelled Tissue and Analysis; Journal of Visualized Experiments; Vol. 17; No. 183; Art. No. e63824; PMCID PMC9549918; 10.3791/63824
• Du, Jiajun and Wei, Lu (2022) Multicolor Photoactivatable Raman Probes for Subcellular Imaging and Tracking by Cyclopropenone Caging; Journal of the American Chemical Society; Vol. 144; No. 2; 777-786; 10.1021/jacs.1c09689
• Aguado, Brian and Bray, Laura J., el al. (2021) 35 challenges in materials science being tackled by PIs under 35(ish) in 2021; Matter; Vol. 4; No. 12; 3804-3810; 10.1016/j.matt.2021.11.003
• Lin, Li-En and Miao, Kun, el al. (2021) High spatial-resolution imaging of label-free in vivo protein aggregates by VISTA; Analyst; Vol. 146; No. 13; 4135-4145; PMCID PMC8238904; 10.1039/d1an00060h
• Qian, Chenxi and Miao, Kun, el al. (2021) Super-resolution label-free volumetric vibrational imaging; Nature Communications; Vol. 12; Art. No. 3648; PMCID PMC8206358; 10.1038/s41467-021-23951-x
• Lee, Dongkwan and Qian, Chenxi, el al. (2021) Toward photoswitchable electronic pre-resonance stimulated Raman probes; Journal of Chemical Physics; Vol. 154; No. 13; Art. No. 135102; PMCID PMC8019356; 10.1063/5.0043791
• Lee, Dongkwan and Du, Jiajun, el al. (2020) Visualizing Subcellular Enrichment of Glycogen in Live Cancer Cells by Stimulated Raman Scattering; Analytical Chemistry; Vol. 92; No. 19; 13182-13191; PMCID PMC10676777; 10.1021/acs.analchem.0c02348
• Du, Jiajun and Su, Yapeng, el al. (2020) Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells; Nature Communications; Vol. 11; Art. No. 4830; PMCID PMC7518429; 10.1038/s41467-020-18376-x
• Du, Jiajun and Su, Yapeng, el al. (2020) Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma
• Miao, Kun and Wei, Lu (2020) Live-Cell Imaging and Quantification of PolyQ Aggregates by Stimulated Raman Scattering of Selective Deuterium Labeling; ACS Central Science; Vol. 6; No. 4; 478-486; PMCID PMC7181319; 10.1021/acscentsci.9b01196
• Wei, Lu (2020) Chemical probes for optical bio-imaging (Conference Presentation); ISBN 9781510632752; Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications XII; Art. No. 112560E; 10.1117/12.2551679
• Wei, Lu and Miao, Kun, el al. (2020) Stimulated Raman imaging with chemical probes for subcellular bioanalysis (Conference Presentation); ISBN 9781510632677; Advanced Chemical Microscopy for Life Science and Translational Medicine; Art. No. 112521S; 10.1117/12.2546942
• Wei, Lu (2020) High-sensitivity stimulated Raman imaging with chemical tags (Conference Presentation); ISBN 9781510632639; High-Speed Biomedical Imaging and Spectroscopy V; Art. No. 112500R; 10.1117/12.2548543
• Wei, Lu (2019) Stimulated Raman imaging with chemical probes for subcellular bioanalysis
• Xiong, Hanqing and Shi, Lixue, el al. (2019) Stimulated Raman excited fluorescence spectroscopy and imaging; Nature Photonics; Vol. 13; No. 6; 412-417; PMCID PMC7326316; 10.1038/s41566-019-0396-4
• Wei, Mian and Shi, Lingyan, el al. (2019) Volumetric chemical imaging by clearing-enhanced stimulated Raman scattering microscopy; Proceedings of the National Academy of Sciences of the United States of America; Vol. 116; No. 14; 6608-6617; PMCID PMC6452712; 10.1073/pnas.1813044116
• Shi, Lixue and Xiong, Hanqing, el al. (2018) Electronic Resonant Stimulated Raman Scattering Micro-Spectroscopy; Journal of Physical Chemistry B; Vol. 122; No. 39; 9218-9224; PMCID PMC6425473; 10.1021/acs.jpcb.8b07037
• Wei, Lu and Min, Wei (2018) Electronic Preresonance Stimulated Raman Scattering Microscopy; Journal of Physical Chemistry Letters; Vol. 9; No. 15; 4294-4301; PMCID PMC6077771; 10.1021/acs.jpclett.8b00204
• Cheng, Qian and Wei, Lu, el al. (2018) Operando and three-dimensional visualization of anion depletion and lithium growth by stimulated Raman scattering microscopy; Nature Communications; Vol. 9; Art. No. 2942; PMCID PMC6065384; 10.1038/s41467-018-05289-z
• Wei, Lu (2018) Nonlinear optical microscopy for the invisible: vibrational imaging of small molecules in live cells and electronic imaging of fluorophores into the ultra deep; 10.7916/D81J991F
• Hu, Fanghao and Zeng, Chen, el al. (2018) Supermultiplexed optical imaging and barcoding with engineered polyynes; Nature Methods; Vol. 15; No. 3; 194-200; PMCID PMC5831481; 10.1038/nmeth.4578
• Wei, Lu and Chen, Zhixing, el al. (2017) Super-multiplex vibrational imaging; Nature; Vol. 544; No. 7651; 465-470; PMCID PMC5939925; 10.1038/nature22051
• Hu, Fanghao and Lamprecht, Michael R., el al. (2016) Bioorthogonal chemical imaging of metabolic activities in live mammalian hippocampal tissues with stimulated Raman scattering; Scientific Reports; Vol. 6; Art. No. 39660; PMCID PMC5175176; 10.1038/srep39660
• Wei, Lu and Hu, Fanghao, el al. (2016) Live-Cell Bioorthogonal Chemical Imaging: Stimulated Raman Scattering Microscopy of Vibrational Probes; Accounts of Chemical Research; Vol. 49; No. 8; 1494-1502; PMCID PMC5704954; 10.1021/acs.accounts.6b00210
• Hu, Fanhao and Chen, Zhixing, el al. (2016) Vibrational imaging of glucose uptake activity in live cells and tissues by stimulated Raman scattering microscopy; ISBN 9781628419573; Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications VIII; Art. No. 97230B; 10.1117/12.2211787
• Wei, Lu and Min, Wei (2016) Optical Imaging of Vibrationally-Tagged Small molecules for Biomedicine; ISBN 978-1-943580-10-1; Biomedical Optics 2016; Art. No. BTh2D.2; 10.1364/BRAIN.2016.BTh2D.2
• Hu, Fanghao and Chen, Zhixing, el al. (2015) Vibrational Imaging of Glucose Uptake Activity in Live Cells and Tissues by Stimulated Raman Scattering; Angewandte Chemie International Edition; Vol. 54; No. 34; 9821-9825; PMCID PMC4644272; 10.1002/anie.201502543
• Wei, Lu and Shen, Yihui, el al. (2015) Imaging complex protein metabolism in live organisms by stimulated Raman scattering microscopy with isotope labeling; ACS Chemical Biology; Vol. 10; No. 3; 901-908; PMCID PMC4610303; 10.1021/cb500787b
• Hu, Fanghao and Chen, Zhixing, el al. (2015) Vibrational Imaging of Glucose Uptake in Live Cells and Tissues by Stimulated Raman Scattering Microscopy; Biophysical Journal; Vol. 108; No. 2; 480A; 10.1016/j.bpj.2014.11.2621
• Chen, Zhixing and Paley, Daniel W., el al. (2014) Multicolor Live-Cell Chemical Imaging by Isotopically Edited Alkyne Vibrational Palette; Journal of the American Chemical Society; Vol. 136; No. 22; 8027-8033; PMCID PMC4063185; 10.1021/ja502706q
• Shen, Yihui and Xu, Fang, el al. (2014) Live-cell quantitative imaging of proteome degradation by stimulated Raman scattering; Angewandte Chemie International Edition; Vol. 53; No. 22; 5596-5599; PMCID PMC4231775; 10.1002/anie.201310725
• Hu, Fanghao and Wei, Lu, el al. (2014) Live-cell vibrational imaging of choline metabolites by stimulated Raman scattering coupled with isotope-based metabolic labeling; Analyst; Vol. 139; No. 10; 2312-2317; PMCID PMC4069604; 10.1039/c3an02281a
• Wei, Lu and Hu, Fanghao, el al. (2014) Live-cell imaging of alkyne-tagged small biomolecules by stimulated Raman scattering; Nature Methods; Vol. 11; No. 4; 410-412; PMCID PMC4040164; 10.1038/nmeth.2878
• Wei, Lu and Zhu, Xinxin, el al. (2014) Super-nonlinear fluorescence microscopy for high-contrast deep tissue imaging; ISBN 9780819498618; Multiphoton Microscopy in the Biomedical Sciences XIV; Art. No. 894825; 10.1117/12.2038753
• Wei, Lu and Yu, Yong, el al. (2013) Vibrational imaging of newly synthesized proteins in live cells by stimulated Raman scattering microscopy; Proceedings of the National Academy of Sciences of the United States of America; Vol. 110; No. 28; 11226-11231; PMCID PMC3710790; 10.1073/pnas.1303768110
• Wei, Lu and Min, Wei (2013) What can stimulated emission do for bioimaging?; Annals of the New York Academy of Sciences; Vol. 1293; 1-7; 10.1111/nyas.12079
• Xu, Fang and Wei, Lu, el al. (2013) Frustrated FRET for high-contrast high-resolution two-photon imaging; Optics Express; Vol. 21; No. 12; 14097-14108; 10.1364/oe.21.014097
• Gatzogiannis, Evangelos and Chen, Zhixing, el al. (2012) Mapping protein-specific micro-environments in live cells by fluorescence lifetime imaging of a hybrid genetic-chemical molecular rotor tag; Chemical Communications; Vol. 48; No. 69; 8694-8696; PMCID PMC3775488; 10.1039/c2cc33133k
• Chen, Zhixing and Wei, Lu, el al. (2012) Extending the fundamental imaging-depth limit of multi-photon microscopy by imaging with photo-activatable fluorophores; Optics Express; Vol. 20; No. 17; 18525-18536; 10.1364/oe.20.018525
• Wei, Lu and Chen, Zhixing, el al. (2012) Stimulated emission reduced fluorescence microscopy: a concept for extending the fundamental depth limit of two-photon fluorescence imaging; Biomedical Optics Express; Vol. 3; No. 6; 1465-1475; PMCID PMC3370985; 10.1364/boe.3.001465
• Wei, Lu and Min, Wei (2012) Pump-probe optical microscopy for imaging nonfluorescent chromophores; Analytical and Bioanalytical Chemistry; Vol. 403; No. 8; 2197-2202; 10.1007/s00216-012-5890-1