Stathopoulos, Angelike

Combined from CaltechAUTHORS

• Dunipace, Leslie and McGehee, James M, el al. (2025) The proximal enhancer of the snail gene mediates negative autoregulatory feedback in Drosophila melanogaster; Genetics; Vol. 230; No. 2; iyaf058; PMCID PMC12135202; 10.1093/genetics/iyaf058
• Pimmett, Virginia L and McGehee, James, el al. (2024) Optogenetic manipulation of nuclear Dorsal reveals temporal requirements and consequences for transcription; 10.1101/2024.11.28.623729
• Sun, Jingjing and Durmaz, Ayse Damla, el al. (2024) Two sequential gene expression programs bridged by cell division support long-distance collective cell migration; Development; Vol. 151; No. 10; dev202262; PMCID PMC11165717; 10.1242/dev.202262
• Sun, Jingjing and Zhang, Chen, el al. (2023) Single-cell transcriptomics illuminates regulatory steps driving anterior-posterior patterning of Drosophila embryonic mesoderm; Cell Reports; Vol. 42; No. 10; 113289; PMCID PMC10704487; 10.1016/j.celrep.2023.113289
• Macabenta, Frank and Sun, Hsuan-Te, el al. (2022) BMP-gated cell-cycle progression drives anoikis during mesenchymal collective migration; Developmental Cell; Vol. 57; No. 14; 1683-1693; PMCID PMC9339487; 10.1016/j.devcel.2022.05.017
• Dunipace, Leslie and Newcomb, Susan, el al. (2022) Brinker levels regulated by a promoter proximal element support germ cell homeostasis; Development; Vol. 149; No. 3; Art. No. dev199890; PMCID PMC8918798; 10.1242/dev.199890
• Ákos, Zsuzsa and Dunipace, Leslie, el al. (2021) NaNuTrap: a technique for in vivo cell nucleus labelling using nanobodies; Development; Vol. 148; No. 18; Art. No. dev199822; 10.1242/dev.199822
• Stevens, Leslie M. and Kim, Goheun, el al. (2021) Light-dependent N-end rule-mediated disruption of protein function in Saccharomyces cerevisiae and Drosophila melanogaster; PLOS Genetics; Vol. 17; No. 5; Art. No. e1009544; 10.1371/journal.pgen.1009544
• Irizarry, Jihyun and McGehee, James, el al. (2021) High levels of Dorsal transcription factor downregulate, not promote, snail expression by regulating enhancer action; 10.1101/2021.01.11.426256
• Irizarry, Jihyun and Stathopoulos, Angelike (2021) Dynamic patterning by morphogens illuminated by cis-regulatory studies; Development; Vol. 148; No. 2; Art. No. dev196113; PMCID PMC7847269; 10.1242/dev.196113
• Stepanik, Vincent and Sun, Jingjing, el al. (2020) FGF Pyramus Has a Transmembrane Domain and Cell-Autonomous Function in Polarity; Current Biology; Vol. 30; No. 16; 3141-3153; PMCID PMC7748623; 10.1016/j.cub.2020.06.006
• Koromila, Theodora and Gao, Fan, el al. (2020) Odd-paired is a pioneer-like factor that coordinates with Zelda to control gene expression in embryos; eLife; Vol. 9; Art. No. e59610; PMCID PMC7417190; 10.7554/eLife.59610
• Irizarry, Jihyun and McGehee, James, el al. (2020) Twist-dependent ratchet functioning downstream from Dorsal revealed using a light-inducible degron; Genes and Development; Vol. 34; No. 13-14; 965-972; PMCID PMC7328519; 10.1101/gad.338194.120
• Sun, Jingjing and Macabenta, Frank, el al. (2020) Collective Migrations of Drosophila Embryonic Trunk and Caudal Mesoderm-Derived Muscle Precursor Cells; Genetics; Vol. 215; No. 2; 297-322; PMCID PMC7268997; 10.1534/genetics.120.303258
• Stathopoulos, Angelike and Newcomb, Susan (2020) Setting up for gastrulation: D. melanogaster; ISBN 978-0-12-812798-8; Gastrulation: From Embryonic Pattern to Form; 3-32; PMCID PMC7296044; 10.1016/bs.ctdb.2019.11.004
• Dunipace, Leslie and Akos, Zsuzsa, el al. (2019) Coacting enhancers can have complementary functions within gene regulatory networks and promote canalization; PLOS Genetics; Vol. 15; No. 12; Art. No. e1008525; PMCID PMC6932828; 10.1371/journal.pgen.1008525
• Macabenta, Frank and Stathopoulos, Angelike (2019) Sticking to a plan: adhesion and signaling control spatial organization of cells within migrating collectives; Current Opinion in Genetics and Development; Vol. 57; 39-46; PMCID PMC6927539; 10.1016/j.gde.2019.07.003
• Koromila, Theodora and Stathopoulos, Angelike (2019) Distinct Roles of Broadly Expressed Repressors Support Dynamic Enhancer Action and Change in Time; Cell Reports; Vol. 28; No. 4; 855-863; PMCID PMC6927530; 10.1016/j.celrep.2019.06.063
• Macabenta, Frank and Stathopoulos, Angelike (2019) Migrating cells control morphogenesis of substratum serving as track to promote directional movement of the collective; Development; Vol. 146; No. 14; Art. No. dev177295; PMCID PMC6679368; 10.1242/dev.177295
• Sandler, Jeremy E. and Irizarry, Jihyun, el al. (2018) A Developmental Program Truncates Long Transcripts to Temporally Regulate Cell Signaling; Developmental Cell; Vol. 47; No. 6; 773-784; PMCID PMC6506262; 10.1016/j.devcel.2018.11.019
• Sun, Jingjing and Stathopoulos, Angelike (2018) FGF controls epithelial-mesenchymal transitions during gastrulation by regulating cell division and apicobasal polarity; Development; Vol. 145; No. 19; Art. No. dev161927; PMCID PMC6198468; 10.1242/dev.161927
• Bae, Young-Kyung and Macabenta, Frank, el al. (2017) Comparative analysis of gene expression profiles for several migrating cell types identifies cell migration regulators; Mechanisms of Development; Vol. 148; 40-55; PMCID PMC5647216; 10.1016/j.mod.2017.04.004
• Koromila, Theodora and Stathopoulos, Angelike (2017) Broadly expressed repressors integrate patterning across orthogonal axes in embryos; Proceedings of the National Academy of Sciences of the United States of America; Vol. 114; No. 31; 8295-8300; PMCID PMC5547611; 10.1073/pnas.1703001114
• Stepanik, Vincent and Dunipace, Leslie, el al. (2016) The migrations of Drosophila muscle founders and primordial germ cells are interdependent; Development; Vol. 143; No. 17; 3206-3215; PMCID PMC5047670; 10.1242/dev.134346
• Sandler, Jeremy E. and Stathopoulos, Angelike (2016) Stepwise Progression of Embryonic Patterning; Trends in Genetics; Vol. 32; No. 7; 432-443; PMCID PMC5065017; 10.1016/j.tig.2016.04.004
• Sandler, Jeremy E. and Stathopoulos, Angelike (2016) Quantitative Single-Embryo Profile of Drosophila Genome Activation and the Dorsal-Ventral Patterning Network; Genetics; Vol. 202; No. 4; 1575-1584; PMCID PMC4905543; 10.1534/genetics.116.186783
• Irizarry, Jihyun and Stathopoulos, Angelike (2015) FGF signaling supports Drosophila fertility by regulating development of ovarian muscle tissues; Developmental Biology; Vol. 404; No. 1; 1-13; PMCID PMC4469552; 10.1016/j.ydbio.2015.04.023
• Trisnadi, Nathanie and Stathopoulos, Angelike (2015) Ectopic Expression Screen Identifies Genes Affecting Drosophila Mesoderm Development Including the HSPG Trol; G3; Vol. 5; No. 2; 301-313; PMCID PMC4321038; 10.1534/g3.114.015891
• Ozdemir, Anil and Ma, Lijia, el al. (2014) Su(H)-Mediated Repression Positions Gene Boundaries along the Dorsal-Ventral Axis of Drosophila Embryos; Developmental Cell; Vol. 31; No. 1; 100-113; PMCID PMC4201238; 10.1016/j.devcel.2014.08.005
• Stathopoulos, Angelike and Iber, Dagmar (2013) Studies of morphogens: keep calm and carry on; Development; Vol. 140; No. 20; 4119-4124; PMCID PMC3787753; 10.1242/dev.095141
• Dunipace, Leslie and Saunders, Abbie, el al. (2013) Autoregulatory Feedback Controls Sequential Action of cis-Regulatory Modules at the brinker Locus; Developmental Cell; Vol. 26; No. 5; 536-543; PMCID PMC3782659; 10.1016/j.devcel.2013.08.010
• Garcia, Mayra and Nahmad, Marcos, el al. (2013) Size-dependent regulation of dorsal–ventral patterning in the early Drosophila embryo; Developmental Biology; Vol. 381; No. 1; 286-299; PMCID PMC3968923; 10.1016/j.ydbio.2013.06.020
• Trisnadi, Nathanie and Altinok, Alphan, el al. (2013) Image analysis and empirical modeling of gene and protein expression; Methods; Vol. 62; No. 1; 68-78; PMCID PMC3807737; 10.1016/j.ymeth.2012.09.016
• Jin, Hong and Stojnic, Robert, el al. (2013) Genome-Wide Screens for In Vivo Tinman Binding Sites Identify Cardiac Enhancers with Diverse Functional Architectures; PLoS Genetics; Vol. 9; No. 1; Art. No. e1003195; PMCID PMC3542182; 10.1371/journal.pgen.1003195
• Bae, Young-Kyung and Trisnadi, Nathanie, el al. (2012) The role of FGF signaling in guiding coordinate movement of cell groups: Guidance cue and cell adhesion regulator?; Cell Adhesion and Migration; Vol. 6; No. 5; 397-403; PMCID PMC3496675; 10.4161/cam.21103
• Reeves, Gregory T. and Trisnadi, Nathanie, el al. (2012) Dorsal-Ventral Gene Expression in the Drosophila Embryo Reflects the Dynamics and Precision of the Dorsal Nuclear Gradient; Developmental Cell; Vol. 22; No. 3; 544-557; PMCID PMC3469262; 10.1016/j.devcel.2011.12.007
• Kadam, Snehalata and Ghosh, Srimoyee, el al. (2012) Synchronous and symmetric migration of Drosophila caudal visceral mesoderm cells requires dual input by two FGF ligands; Development; Vol. 139; No. 4; 699-708; PMCID PMC3265058; 10.1242/dev.068791
• Garcia, Mayra and Stathopoulos, Angelike (2011) Lateral Gene Expression in Drosophila Early Embryos Is Supported by Grainyhead-Mediated Activation and Tiers of Dorsally-Localized Repression; PLoS ONE; Vol. 6; No. 12; e29172; PMCID PMC3245246; 10.1371/journal.pone.0029172
• Ozdemir, Anil and Stathopoulos, Angelike (2011) Exciting times: bountiful data to facilitate studies of cis-regulatory control; Nature Methods; Vol. 8; No. 12; 1016-1017; 10.1038/nmeth.1795
• Dunipace, Leslie and Ozdemir, Anil, el al. (2011) Complex interactions between cis-regulatory modules in native conformation are critical for Drosophila snail expression; Development; Vol. 138; No. 18; 4075-4084; PMCID PMC3160101; 10.1242/dev.069146
• Ozdemir, Anil and Fisher-Aylor, Katherine I., el al. (2011) High resolution mapping of Twist to DNA in Drosophila embryos: Efficient functional analysis and evolutionary conservation; Genome Research; Vol. 21; No. 4; 566-577; PMCID PMC3065704; 10.1101/gr.104018.109
• Nahmad, Marcos and Stathopoulos, Angelike (2010) Establishing positional information through gradient dynamics: a lesson from the Hedgehog signaling pathway; Fly; Vol. 4; No. 4; 273-277; PMCID PMC3174477; 10.4161/fly.4.4.12677
• Tulin, Sarah and Stathopoulos, Angelike (2010) Extending the family table: Insights from beyond vertebrates into the regulation of embryonic development by FGFs; Birth Defects Research Part C – Embryo Today – Reviews; Vol. 90; No. 3; 214-227; PMCID PMC4121331; 10.1002/bdrc.20182
• Tulin, Sarah and Stathopoulos, Angelike (2010) Analysis of Thisbe and Pyramus functional domains reveals evidence for cleavage of Drosophila FGFs; BMC Developmental Biology; Vol. 10; Art. No. 83; PMCID PMC2923630; 10.1186/1471-213X-10-83
• McMahon, Amy and Reeves, Gregory T., el al. (2010) Mesoderm migration in Drosophila is a multi-step process requiring FGF signaling and integrin activity; Development; Vol. 137; No. 13; 2167-2175; PMCID PMC2882136; 10.1242/dev.051573
• Liberman, Louisa M. and Reeves, Gregory T., el al. (2009) Quantitative imaging of the Dorsal nuclear gradient reveals limitations to threshold-dependent patterning in Drosophila; Proceedings of the National Academy of Sciences of the United States of America; Vol. 106; No. 52; 22317-22322; PMCID PMC2799780; 10.1073/pnas.0906227106
• Reeves, Gregory T. and Stathopoulos, Angelike (2009) Graded Dorsal and Differential Gene Regulation in the Drosophila Embryo; Cold Spring Harbor Perspectives in Biology; Vol. 1; No. 4; Art. No. a000836; PMCID PMC2773625; 10.1101/cshperspect.a000836
• Supatto, Willy and McMahon, Amy, el al. (2009) Quantitative imaging of collective cell migration during Drosophila gastrulation: multiphoton microscopy and computational analysis; Nature Protocols; Vol. 4; No. 10; 1397-1412; PMCID PMC2854020; 10.1038/nprot.2009.130
• Nahmad, Marcos and Stathopoulos, Angelike (2009) Dynamic Interpretation of Hedgehog Signaling in the Drosophila Wing Disc; PLoS Biology; Vol. 7; No. 9; e1000202; PMCID PMC2744877; 10.1371/journal.pbio.1000202
• Supatto, Willy and McMahon, Amy, el al. (2009) Quantitative imaging of the collective cell movements shaping an embryo; ISBN 978-1-4244-2940-0; 42nd Asilomar Conference on Signals, Systems and Computers; 61-63; 10.1109/ACSSC.2008.5074361
• Liberman, Louisa M. and Stathopoulos, Angelike (2009) Design flexibility in cis-regulatory control of gene expression: synthetic and comparative evidence; Developmental Biology; Vol. 327; No. 2; 578-589; PMCID PMC2746413; 10.1016/j.ydbio.2008.12.020
• Kadam, Snehalata and McMahon, Amy, el al. (2009) FGF ligands in Drosophila have distinct activities required to support cell migration and differentiation; Development; Vol. 136; No. 5; 739-747; PMCID PMC2685942; 10.1242/dev.027904
• McMahon, Amy and Supatto, Willy, el al. (2008) Dynamic Analyses of Drosophila Gastrulation Provide Insights into Collective Cell Migration; Science; Vol. 322; No. 5907; 1546-1550; PMCID PMC2801059; 10.1126/science.1167094
• Stathopoulos, Angelike and Levine, Michael (2005) Genomic Regulatory Networks and Animal Development; Developmental Cell; Vol. 9; No. 4; 449-462; 10.1016/j.devcel.2005.09.005
• Stathopoulos, Angelike and Levine, Michael (2005) Localized repressors delineate the neurogenic ectoderm in the early Drosophila embryo; Developmental Biology; Vol. 280; No. 2; 482-493; 10.1016/j.ydbio.2005.02.003
• Stathopoulos, Angelike and Levine, Michael (2004) Whole-genome analysis of Drosophila gastrulation; Current Opinion in Genetics and Development; Vol. 14; No. 5; 477-484; 10.1016/j.gde.2004.07.004
• Markstein, Michelle and Zinzen, Robert, el al. (2004) A regulatory code for neurogenic gene expression in the Drosophila embryo; Development; Vol. 131; No. 10; 2387-2394; 10.1242/10.1242/dev.01124
• Stathopoulos, Angelique and Tam, Bergin, el al. (2004) pyramus and thisbe: FGF genes that pattern the mesoderm of Drosophila embryos; Genes and Development; Vol. 18; No. 6; 687-699; PMCID PMC387243; 10.1101/gad.1166404
• Stathopoulos, Angelike and Van Drenth, Madeleine, el al. (2002) Whole-Genome Analysis of Dorsal-Ventral Patterning in the Drosophila Embryo; Cell; Vol. 111; No. 5; 687-701; 10.1016/S0092-8674(02)01087-5
• Stathopoulos, Angelike and Levine, Michael (2002) Whole-Genome Expression Profiles Identify Gene Batteries in Drosophila; Developmental Cell; Vol. 3; No. 4; 464-465; 10.1016/S1534-5807(02)00300-3
• Stathopoulos, Angelike and Levine, Michael (2002) Linear signaling in the Toll-Dorsal pathway of Drosophila: activated Pelle kinase specifies all threshold outputs of gene expression while the bHLH protein Twist specifies a subset; Development; Vol. 129; No. 14; 3411-3419
• Calhoun, Vincent C. and Stathopoulos, Angelike, el al. (2002) Promoter-proximal tethering elements regulate enhancer-promoter specificity in the Drosophila Antennapedia complex; Proceedings of the National Academy of Sciences of the United States of America; Vol. 99; No. 14; 9243-9247; PMCID PMC123125; 10.1073/pnas.142291299
• Stathopoulos, Angelike and Levine, Michael (2002) Dorsal Gradient Networks in the Drosophila Embryo; Developmental Biology; Vol. 246; No. 1; 57-67; 10.1006/dbio.2002.0652
• Stathopoulos-Gerontides, Angelike and Guo, Jim Jun, el al. (1999) Yeast calcineurin regulates nuclear localization of the Crz1p transcription factor through dephosphorylation; Genes and Development; Vol. 13; No. 7; 798-803; PMCID PMC316598
• Stathopoulos, Angelike M. and Cyert, Martha S. (1997) Calcineurin acts through the CRZ1/TCN1-encoded transcription factor to regulate gene expression in yeast; Genes and Development; Vol. 11; No. 24; 3432-3444; PMCID PMC316814; 10.1101/gad.11.24.3432