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Hunkapiller, Michael W.
at Caltech
PhD (1974)
Nuclear magnetic resonance studies of the catalytic mechanism of proteolytic enzymes. Ionization behavior of the histidine residue in the catalytic triad of alpha-lytic protease--implications for the catalytic mechanism of serine proteases. Ionization behavior of enzymic and inhibitor groups in the tetrahedral adduct between alpha-lytic protease and a peptide aldehyde. Kinetics of pepsin-catalyzed hydrolysis of N-tri-fluoroacetyl amino acids
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