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Britten, Roy J.
Britten, Roy J. (2010) Transposable element insertions have strongly affected human evolution ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 107; No. 46; 19945-19948; PMCID PMC2993358; 10.1073/pnas.1014330107
Gleick, P. H. and Anderson, D. J., el al. (2010) Climate Change and the Integrity of Science ; Science; Vol. 328; No. 5979; 689-690; PMCID PMC5125622; 10.1126/science.328.5979.689
Britten, Roy J. (2008) Idiosyncratic evolution of conserved eukaryote proteins that are similar in sequence to archaeal or bacterial proteins ; Nature Precedings; 10.1038/npre.2008.1752.1
Britten, Roy (2006) Almost all human genes resulted from ancient duplication ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 103; No. 50; 19027-19032; PMCID PMC1748171; 10.1073/pnas.0510007103
Britten, Roy J. (2005) The majority of human genes have regions repeated in other human genes ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 102; No. 15; 5466-5470; PMCID PMC555776; 10.1073/pnas.0501008102
Britten, Roy J. (2004) Coding sequences of functioning human genes derived entirely from mobile element sequences ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 101; No. 48; 16825-16830; PMCID PMC534736
Britten, Roy J. and Rowen, Lee, el al. (2003) Majority of divergence between closely related DNA samples is due to indels ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 100; No. 8; 4661-4665; PMCID PMC153612; 10.1073/pnas.0330964100
Britten, Roy J. (2002) Divergence between samples of chimpanzee and human DNA sequences is 5%, counting indels ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 99; No. 21; 13633-13635; PMCID PMC129726; 10.1073/pnas.172510699
Cameron, R. Andrew and Mahairas, Gregory, el al. (2000) A sea urchin genome project: Sequence scan, virtual map, and additional resources ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 97; No. 17; 9514-9518; PMCID PMC16896; 10.1073/pnas.160261897
Lee, Youn-Ho and Huang, Guyang Matthew, el al. (1999) EST analysis of gene expression in early cleavage-stage sea urchin embryos ; Development; Vol. 126; No. 17; 3857-3867
Lee, Youn-Ho and Britten, Roy J., el al. (1999) SM37, a skeletogenic gene of the sea urchin embryo linked to the SM50 gene ; Development, Growth & Differentiation; Vol. 41; No. 3; 303-312; 10.1046/j.1440-169X.1999.413429.x
Cameron, R. Andrew and Leahy, Patrick S., el al. (1999) Microsatellite Loci in Wild-Type and Inbred Strongylocentrotus purpuratus ; Developmental Biology; Vol. 208; No. 2; 255-264; 10.1006/dbio.1999.9224
Britten, Roy J. (1998) Underlying assumptions of developmental models ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 95; No. 16; 9372-9377; PMCID PMC21345; 10.1073/pnas.95.16.9372
Britten, Roy J. (1998) Precise sequence complementarity between yeast chromosome ends and two classes of just-subtelomeric sequences ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 95; No. 11; 5906-5912; PMCID PMC34494
Britten, Roy J. (1998) A gravitational diffusion model without dark matter ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 95; No. 7; 3351-3355; PMCID PMC19838
Britten, Roy J. (1997) Mobile elements inserted in the distant past have taken on important functions ; Gene; Vol. 205; No. 1-2; 177-182; 10.1016/S0378-1119(97)00399-5
Britten, Roy J. (1996) DNA sequence insertion and evolutionary variation in gene regulation ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 93; No. 18; 9374-9377; PMCID PMC38434
Britten, Roy J. (1996) Cases of Ancient Mobile Element DNA Insertions That Now Affect Gene Regulation ; Molecular Phylogenetics and Evolution; Vol. 5; No. 1; 13-17; 10.1006/mpev.1996.0003
Smith, L. Courtney and Chang, Lily, el al. (1996) Sea Urchin Genes Expressed in Activated Coelomocytes Are Identified by Expressed Sequence Tags. Complement Homologues and Other Putative Immune Response Genes Suggest Immune System Homology Within the Deuterostomes ; Journal of Immunology; Vol. 156; No. 2; 593-602
Makabe, Kazuhiro W. and Kirchhamer, Carmen V., el al. (1995) Cis-regulatory control of the SM50 gene, an early marker of skeletogenic lineage specification in the sea urchin embryo ; Development; Vol. 121; No. 7; 1957-1970
Zeller, Robert W. and Britten, Roy J., el al. (1995) Developmental Utilization of SpP3A1 and SpP3A2: Two Proteins Which Recognize the Same DNA Target Site in Several Sea Urchin Gene Regulatory Regions ; Developmental Biology; Vol. 170; No. 1; 75-82; 10.1006/dbio.1995.1196
Wang, D. G. and Britten, R. J., el al. (1995) Maternal and embryonic provenance of a sea urchin embryo transcription factor, SpZ12-1 ; Molecular Marine Biology and Biotechnology; Vol. 4; No. 2; 148-153
Zeller, Robert W. and Coffman, James A., el al. (1995) SpGCF1, a Sea Urchin Embryo DNA-Binding Protein, Exists as Five Nested Variants Encoded by a Single mRNA ; Developmental Biology; Vol. 169; No. 2; 713-727; 10.1006/dbio.1995.1181
Smith, L. Courtney and Britten, Roy J., el al. (1995) Lipopolysaccharide activates the sea urchin immune system ; Developmental and Comparative Immunology; Vol. 19; No. 3; 217-224; 10.1016/0145-305X(95)00009-I
Wang, David G.-W. and Kirchhamer, Carmen V., el al. (1995) SpZ12-1, a negative regulator required for spatial control of the territory-specific CyIIIa gene in the sea urchin embryo ; Development; Vol. 121; No. 4; 1111-1122
Zeller, Robert W. and Griffith, Jack D., el al. (1995) A multimerizing transcription factor of sea urchin embryos capable of looping DNA ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 92; No. 7; 2989-2993; PMCID PMC42344; 10.1073/pnas.92.7.2989
Springer, Mark S. and Tusneem, Nadeem A., el al. (1995) Phylogeny, rates of evolution, and patterns of codon usage among sea urchin retroviral-like elements, with implications for the recognition of horizontal transfer ; Molecular Biology and Evolution; Vol. 12; No. 2; 219-230
Britten, Roy J. (1995) Active gypsy/Ty3 retrotransposons or retroviruses in Caenorhabditis elegans ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 92; No. 2; 599-601; PMCID PMC42789
Britten, Roy J. and McCormack, Thomas J., el al. (1995) Gypsy/Ty3-class retrotransposons integrated in the DNA of herring, tunicate, and echinoderms ; Journal of Molecular Evolution; Vol. 40; No. 1; 13-24; 10.1007/BF00166592
Smith, L. Courtney and Harrington, Michael G., el al. (1994) The sea urchin profilin gene is specifically expressed in mesenchyme cells during gastrulation ; Developmental Biology; Vol. 164; No. 2; 463-474; 10.1006/dbio.1994.1216
Yuh, Chiou-Hwa and Ransick, Andrew, el al. (1994) Complexity and organization of DNA-protein interactions in the 5′-regulatory region of an endoderm-specific marker gene in the sea urchin embryo ; Mechanisms of Development; Vol. 47; No. 2; 165-186; 10.1016/0925-4773(94)90088-4
Britten, Roy J. (1994) Evolutionary selection against change in many Alu repeat sequences interspersed through primate genomes ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 91; No. 13; 5992-5996; PMCID PMC44123
Britten, Roy J. (1994) Evidence that most human Alu sequences were inserted in a process that ceased about 30 million years ago ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 91; No. 13; 6148-6150; PMCID PMC44155
Anderson, Roger and Britten, Roy J., el al. (1994) Repeated Sequence Target Sites for Maternal DNA-Binding Proteins in Genes Activated in Early Sea Urchin Development ; Developmental Biology; Vol. 163; No. 1; 11-18; 10.1006/dbio.1994.1119
Leahy, Patrick S. and Cameron, R. Andrew, el al. (1994) Development of sibling inbred sea urchins: Normal embryogenesis, but frequent postembryonic malformation, arrest and lethality ; Mechanisms of Development; Vol. 45; No. 3; 255-268; 10.1016/0925-4773(94)90012-4
Cameron, R. Andrew and Smith, L. Courtney, el al. (1994) Ligand-dependent stimulation of introduced mammalian brain receptors alters spicule symmetry and other morphogenetic events in sea urchin embryos ; Mechanisms of Development; Vol. 45; No. 1; 31-47; 10.1016/0925-4773(94)90051-5
Cameron, R. Andrew and Britten, Roy J., el al. (1993) The Embryonic Ciliated Band of the Sea Urchin, Strongylocentrotus purpuratus Derives from Both Oral and Aboral Ectoderm ; Developmental Biology; Vol. 160; No. 2; 369-376; 10.1006/dbio.1993.1313
Ransick, Andrew and Ernst, Susan, el al. (1993) Whole mount in situ hybridization shows Endo 16 to be a marker for the vegetal plate territory in sea urchin embryos ; Mechanisms of Development; Vol. 42; No. 3; 117-124; 10.1016/0925-4773(93)90001-E
Minor, Joseph E. and Britten, Roy J., el al. (1993) Species-specific inhibition of fertilization by a peptide derived from the sperm protein bindin ; Molecular Biology of the Cell; Vol. 4; No. 4; 375-387; PMCID PMC300939
Britten, Roy J. (1993) Forbidden Synonymous Substitutions in Coding Regions ; Molecular Biology and Evolution; Vol. 10; No. 1; 205-220
Springer, Mark S. and Britten, Roy J. (1993) Phylogenetic Relationships of Reverse Transcriptase and RNase H Sequences and Aspects of Genome Structure in the Gypsy Group of Retrotransposons ; Molecular Biology and Evolution; Vol. 10; No. 6; 1370-1379
Springer, Mark S. and Britten, Roy J. (1993) DNA-DNA hybridization of single-copy DNA sequences ; ISBN 9780121821258; Molecular Evolution: Producing the Biochemical Data; 232-243; 10.1016/0076-6879(93)24018-P
Harrington, Michael G. and Coffman, James A., el al. (1992) Complexity of Sea Urchin Embryo Nuclear Proteins That Contain Basic Domains ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 89; No. 14; 6252-6256; PMCID PMC49478
Zeller, Robert W. and Cameron, R. Andrew, el al. (1992) Territorial Expression of Three Different trans-Genes in Early Sea Urchin Embryos Detected by a Whole-Mount Fluorescence Procedure ; Developmental Biology; Vol. 151; No. 2; 382-390; 10.1016/0012-1606(92)90178-J
Britten, Roy J. (1992) Graviton scattering and matter distribution ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 89; No. 9; 4086-4090; PMCID PMC525637
Springer, Mark S. and Davidson, Eric H., el al. (1992) Calculation of sequence divergence from the thermal stability of DNA heteroduplexes ; Journal of Molecular Evolution; Vol. 34; No. 5; 379-382; 10.1007/BF00162994
Smith, L. Courtney and Britten, Roy J., el al. (1992) SpCoel1: a sea urchin profilin gene expressed specifically in coelomocytes in response to injury ; Molecular Biology of the Cell; Vol. 3; No. 4; 403-414; PMCID PMC275591
Coffman, J. A. and Moore, J. G., el al. (1992) Automated sequential affinity chromatography of sea urchin embryo DNA binding proteins ; Molecular Marine Biology and Biotechnology; Vol. 1; No. 2; 136-46
Cameron, R. Andrew and Fraser, Scott E., el al. (1991) Macromere cell fates during sea urchin development ; Development; Vol. 113; No. 4; 1085-1091
Minor, Joseph E. and Fromson, David R., el al. (1991) Comparison of the Hindin Proteins of Strongylocentrotus franciscanus, S. purpuratus, and Lytechinus variegatus: Sequences involved in the Species Specificity of Fertilization ; Molecular Biology and Evolution; Vol. 8; No. 6; 781-795
Springer, Mark S. and Davidson, Eric H., el al. (1991) Retroviral-Like Element in a Marine Invertebrate ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 88; No. 19; 8401-8404; PMCID PMC52516
Livant, Donna L. and Hough-Evans, Barbara R., el al. (1991) Differential stability of expression of similarly specified endogenous and exogenous genes in the sea urchin embryo ; Development; Vol. 113; No. 2; 385-398
Höög, Christer and Calzone, Frank J., el al. (1991) Gene regulatory factors of the sea urchin embryo. II. Two dissimilar proteins, P3A1 and P3A2, bind to the same target sites that are required for early territorial gene expression ; Development; Vol. 112; No. 1; 351-364
Calzone, Frank J. and Höög, Christer, el al. (1991) Gene regulatory factors of the sea urchin embryo. I. Purification by affinity chromatography and cloning of P3A2, a novel DNA-binding protein ; Development; Vol. 112; No. 1; 335-350
Cameron, R. Andrew and Minor, Joseph E., el al. (1990) Locale and Level of Bindin mRNA in Maturing Testis of the Sea Urchin, Strongylocentrotus purpuratus ; Developmental Biology; Vol. 142; No. 1; 44-49; 10.1016/0012-1606(90)90149-D
Cutting, Ann E. and Höög, Christer, el al. (1990) Rare maternal mRNAs code for regulatory proteins that control lineage-specific gene expression in the sea urchin embryo ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 87; No. 20; 7953-7957; PMCID PMC54870
Hough-Evans, Barbara R. and Franks, Roberta R., el al. (1990) Negative spatial regulation of the lineage specific CyIIIa actin gene in the sea urchin embryo ; Development; Vol. 110; No. 1; 41-50
Franks, Roberta R. and Anderson, Roger, el al. (1990) Competitive titration in living sea urchin embryos of regulatory factors required for expression of the CyIIIa actin gene ; Development; Vol. 110; No. 1; 31-40
Britten, Roy J. (1990) Comment on DNA hybridization issues raised at Lake Arrowhead ; Journal of Molecular Evolution; Vol. 30; No. 3; 193-195; 10.1007/BF02099990
Werman, Steven D. and Davidson, Eric H., el al. (1990) Rapid evolution in a fraction of the Drosophila nuclear genome ; Journal of Molecular Evolution; Vol. 30; No. 3; 281-289; 10.1007/BF02099998
Thézé, Nadine and Calzone, Frank J., el al. (1990) Sequences of the CyIIIa actin gene regulatory domain bound specifically by sea urchin embryo nuclear proteins ; Molecular Reproduction and Development; Vol. 25; No. 2; 110-122; 10.1002/mrd.1080250203
Cameron, R. Andrew and Fraser, Scott E., el al. (1990) Segregation of Oral from Aboral Ectoderm Precursors Is Completed at Fifth Cleavage in the Embryogenesis of Strongylocentrotus purpuratus ; Developmental Biology; Vol. 137; No. 1; 77-85; 10.1016/0012-1606(90)90009-8
Thiebaud, Pierre and Goodstein, Marcia, el al. (1990) Intersecting batteries of differentially expressed genes in the early sea urchin embryo ; Genes and Development; Vol. 4; No. 11; 1999-2010; 10.1101/gad.4.11.1999
Cameron, R. Andrew and Fraser, Scott E., el al. (1989) The oral-aboral axis of a sea urchin embryo is specified by first cleavage ; Development; Vol. 106; No. 4; 641-647
Britten, Roy J. and Stout, David B., el al. (1989) The current source of human Alu retroposons is a conserved gene shared with Old World monkey ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 86; No. 10; 3718-3722; PMCID PMC287211
Cameron, R. Andrew and Britten, Roy J., el al. (1989) Expression of two actin genes during larval development in the sea urchin Strongylocentrotus purpuratus ; Molecular Reproduction and Development; Vol. 1; No. 3; 149-155; 10.1002/mrd.1080010302
Franks, Roberta R. and Britten, Roy J., el al. (1989) In vivo competition identifies positive cis-regulatory elements required for lineage-specific gene expression in the sea urchin embryo ; ISBN 9780471923060; Cellular Basis of Morphogenesis; 156-66; discussion 166; 10.1002/9780470513798.ch9
Livant, Donna L. and Cutting, Ann E., el al. (1988) An in vivo Titration of Regulatory Factors Required for Expression of a Fusion Gene in Transgenic Sea Urchin Embryos ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 85; No. 20; 7607-7611; PMCID PMC282241
Sucov, Henry M. and Hough-Evans, Barbara R., el al. (1988) A regulatory domain that directs lineage-specific expression of a skeletal matrix protein gene in the sea urchin embryo ; Genes and Development; Vol. 2; No. 10; 1238-1250; 10.1101/gad.2.10.123
Calzone, Frank J. and Thézé, Nadine, el al. (1988) Developmental appearance of factors that bind specifically to cis-regulatory sequences of a gene expressed in the sea urchin embryo ; Genes and Development; Vol. 2; No. 9; 1074-1088; 10.1101/gad.2.9.1074
Hough-Evans, Barbara R. and Britten, Roy J., el al. (1988) Mosaic Incorporation and Regulated Expression of an Exogenous Gene in the Sea Urchin Embryo ; Developmental Biology; Vol. 129; No. 1; 198-208; 10.1016/0012-1606(88)90174-1
Britten, Roy J. and Baron, Will F., el al. (1988) Sources and evolution of human Alu repeated sequences ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 85; No. 13; 4770-4774; PMCID PMC280517
Calzone, Frank J. and Lee, James J., el al. (1988) A long, nontranslatable poly(A) RNA stored in the egg of the sea urchin Strongylocentrotus purpuratus ; Genes and Development; Vol. 2; No. 3; 305-318; 10.1101/gad.2.3.305
Franks, Roberta R. and Hough-Evans, Barbara R., el al. (1988) Direct introduction of cloned DNA into the sea urchin zygote nucleus, and fate of injected DNA ; Development; Vol. 102; No. 2; 287-299
Franks, Roberta R. and Hough-Evans, Barbara R., el al. (1988) Spatially deranged though temporally correct expression of a Strongylocentrotus purpuratus actin gene fusion in transgenic embryos of a different sea urchin family ; Genes and Development; Vol. 2; No. 1; 1-12; 10.1101/gad.2.1.1
Katula, Karen S. and Hough-Evans, Barbara R., el al. (1987) Ontogenic expression of a CyI actin fusion gene injected into sea urchin eggs ; Development; Vol. 101; No. 3; 437-447
Rose, Samuel J. and Rosenberg, Marvin J., el al. (1987) Expression of Myosin Heavy Chain Gene in the Sea Urchin: Coregulation with Muscle Actin Transcription in Early Development ; Developmental Biology; Vol. 123; No. 1; 115-124; 10.1016/0012-1606(87)90433-7
Minor, Joseph E. and Lee, James J., el al. (1987) Sea Urchin Actin Gene Linkages Determined by Genetic Segregation ; Developmental Biology; Vol. 122; No. 1; 291-295; 10.1016/0012-1606(87)90354-X
Hough-Evans, Barbara R. and Franks, Roberta R., el al. (1987) Correct Cell-Type-Specific Expression of a Fusion Gene
Injected into Sea Urchin Eggs ; Developmental Biology; Vol. 121; No. 2; 576-579; 10.1016/0012-1606(87)90193-X
Sucov, Henry M. and Benson, Steve, el al. (1987) A Lineage-Specific Gene Encoding a Major Matrix Protein of the Sea Urchin Embryo Spicule: II. Structure of the Gene and Derived Sequence of the Protein ; Developmental Biology; Vol. 120; No. 2; 507-519; 10.1016/0012-1606(87)90254-5
Akhurst, Rosemary J. and Calzone, Frank J., el al. (1987) Structure and organization of the CyIII actin gene subfamily of the sea urchin, Strongylocentrotus purpuratus ; Journal of Molecular Biology; Vol. 194; No. 2; 193-203; 10.1016/0022-2836(87)90368-8
Cameron, R. Andrew and Hough-Evans, Barbara R., el al. (1987) Lineage and fate of each blastomere of the eight-cell sea urchin embryo ; Genes and Development; Vol. 1; No. 1; 75-84; 10.1101/gad.1.1.75
Flytzanis, Constantin N. and Britten, Roy J., el al. (1987) Ontogenic activation of a fusion gene introduced into sea urchin eggs ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 84; No. 1; 151-155; PMCID PMC304160; 10.1073/pnas.84.1.151
Gao, Boning and Klein, Laurie E., el al. (1986) Sequence of mRNA Coding for Bindin, a Species-Specific Sea Urchin Sperm Protein Required for Fertilization ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 83; No. 22; 8634-8638; PMCID PMC386985
Hwu, Huey Ru and Roberts, John W., el al. (1986) Insertion and/or Deletion of Many Repeated DNA Sequences in Human and Higher Ape Evolution ; Proceedings of the National Academy of Sciences of the United States of America; Vol. 83; No. 11; 3875-3879; PMCID PMC323627
Britten, Roy J. (1986) Rates of DNA sequence evolution differ between taxonomic groups ; Science; Vol. 231; No. 4744; 1393-1398; 10.1126/science.3082006
Lee, James J. and Calzone, Frank J., el al. (1986) Activation of sea urchin actin genes during embryogenesis: Measurement of transcript accumulation from five different genes in Strongylocentrotus purpuratus ; Journal of Molecular Biology; Vol. 188; No. 2; 173-183; 10.1016/0022-2836(86)90302-5
Roberts, John W. and Johnson, Steven A., el al. (1985) Evolutionary conservation of DNA sequences expressed in sea urchin eggs and early embryos ; Journal of Molecular Evolution; Vol. 22; No. 2; 99-107; 10.1007/BF02101688
Flytzanis, Constantin N. and McMahon, Andrew P., el al. (1985) Persistence and Integration of Cloned DNA in Postembryonic Sea Urchins ; Developmental Biology; Vol. 108; No. 2; 431-442; 10.1016/0012-1606(85)90046-6
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Thomas, Terry L. and Britten, Roy J., el al. (1982) An Interspersed Region of the Sea Urchin Genome Represented in Both Maternal Poly(A) RNA and Embryo Nuclear RNA ; Developmental Biology; Vol. 94; No. 1; 230-239; 10.1016/0012-1606(82)90086-0
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Anderson, David M. and Richter, Joel D., el al. (1982) Sequence Organization of the Poly(A) RNA Synthesized and Accumulated in Lampbrush Chromosome Stage Xenopus laevis Oocytes ; Journal of Molecular Biology; Vol. 155; No. 3; 281-309; 10.1016/0022-2836(82)90006-7
Xin, Ji-Hou and Brandhorst, Bruce P., el al. (1982) Cloned Embryo mRNAs Not Detectably Expressed in Adult Sea Urchin Coelomocytes ; Developmental Biology; Vol. 89; No. 2; 527-531; 10.1016/0012-1606(82)90342-6
Dawid, I. and Britten, R. J., el al. (1982) Genomic Change and Morphological Evolution Group Report ; ISBN 9783642455346; Evolution and Development; 18-39; 10.1007/978-3-642-45532-2_2
Britten, R. J. (1982) Genomic Alterations in Evolution ; ISBN 9783642455346; Evolution and Development; 41-64; 10.1007/978-3-642-45532-2_3
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