Dam, Kim-Marie A.; Fan, Chengcheng; et el. (2023) Intermediate
conformations of CD4-bound HIV-1 Env heterotrimers ; Nature; Vol.
623; No. 7989; 1017-1025; 10.1038/s41586-023-06639-8
Horns, Felix; Martinez, Joe A.; et el. (2023) Engineering
RNA export for measurement and manipulation of living cells ; Cell;
Vol. 186; No. 17; 3642-3658.e32; PMCID PMC10528933; 10.1016/j.cell.2023.06.013
Hoffmann, Magnus A. G.; Yang, Zhi; et el. (2023) ESCRT
recruitment to SARS-CoV-2 spike induces virus-like particles that
improve mRNA vaccines ; Cell; Vol. 186; No. 11; 2380-2391; PMCID
PMC10121106; 10.1016/j.cell.2023.04.024
Shrock, Ellen L.; Timms, Richard T.; et el. (2023) Germline-encoded
amino acid–binding motifs drive immunodominant public antibody
responses ; Science; Vol. 380; No. 6640; Art. No. eadc9498; PMCID
PMC10273302; 10.1126/science.adc9498
Braet, Sean M.; Buckley, Theresa S. C.; et el. (2023) Timeline
of changes in spike conformational dynamics in emergent SARS-CoV-2
variants reveal progressive stabilization of trimer stalk with altered
NTD dynamics ; eLife; Vol. 12; Art. No. e82584; PMCID PMC10049203; 10.7554/elife.82584
Cable, Jennifer; Balachandran, Siddharth; et el. (2023) Viral
immunity: Basic mechanisms and therapeutic applications—a Keystone
Symposia report ; Annals of the New York Academy of Sciences; Vol.
1521; No. 1; 32-45; 10.1111/nyas.14960
Gristick, Harry B.; Hartweger, Harald; et el. (2023) CD4
binding site immunogens elicit heterologous anti–HIV-1 neutralizing
antibodies in transgenic and wild-type animals ; Science Immunology;
Vol. 8; No. 80; eade6364; PMCID PMC10202037; 10.1126/sciimmunol.ade6364
Gristick, Harry B.; Hartweger, Harald; et el. (2023) CD4
binding site immunogens elicit heterologous anti–HIV-1 neutralizing
antibodies in transgenic and wild-type animals ; Science Immunology;
Vol. 8; No. 80; Art. No. eade6364; 10.1126/sciimmunol.ade6364
Huang, Kuan-Ying A.; Chen, Xiaorui; et el. (2023) Structural
basis for a conserved neutralization epitope on the receptor-binding
domain of SARS-CoV-2 ; Nature Communications; Vol. 14; Art. No. 311;
PMCID PMC9852238; 10.1038/s41467-023-35949-8
Yang, Zhi; Dam, Kim-Marie A.; et el. (2022) Antibody
Recognition of CD4-Induced Open HIV-1 Env Trimers ; Journal of
Virology; Vol. 96; No. 24; e0108222; PMCID PMC9769388; 10.1128/jvi.01082-22
Fan, Chengcheng; Cohen, Alexander A.; et el. (2022) Neutralizing
monoclonal antibodies elicited by mosaic RBD nanoparticles bind
conserved sarbecovirus epitopes ; Immunity; Vol. 55; No. 12;
2419-2435.e10; PMCID PMC9606073; 10.1016/j.immuni.2022.10.019
Dam, Kim-Marie A.; Barnes, Christopher O.; et el. (2022) HIV-1
CD4-binding site germline antibody-Env structures inform vaccine
design ; Nature Communications; Vol. 13; Art. No. 6123; PMCID
PMC9576718; 10.1038/s41467-022-33860-2
Barnes, Christopher O.; Schoofs, Till; et el. (2022) A
naturally arising broad and potent CD4-binding site antibody with low
somatic mutation ; Science Advances; Vol. 8; No. 32; Art.
No. eabp8155; 10.1126/sciadv.abp8155
Cohen, Alexander A.; van Doremalen, Neeltje; et el. (2022) Mosaic
RBD nanoparticles protect against challenge by diverse sarbecoviruses in
animal models ; Science; Vol. 377; No. 6606; Art. No. eabq0839; PMCID
PMC9273039; 10.1126/science.abq0839
Dam, Kim-Marie A.; Mutia, Patricia S.; et el. (2022) Comparing
methods for immobilizing HIV-1 SOSIPs in ELISAs that evaluate antibody
binding ; Scientific Reports; Vol. 12; Art. No. 11172; PMCID
PMC9247892; 10.1038/s41598-022-15506-x
Bozhanova, Nina G.; Flyak, Andrew I.; et el. (2022) Computational
identification of HCV neutralizing antibodies with a common HCDR3
disulfide bond motif in the antibody repertoires of infected
individuals ; Nature Communications; Vol. 13; Art. No. 3178; PMCID
PMC9177688; 10.1038/s41467-022-30865-9
Jacobs, Jana L.; Bain, William; et el. (2022) Severe
Acute Respiratory Syndrome Coronavirus 2 Viremia Is Associated With
Coronavirus Disease 2019 Severity and Predicts Clinical Outcome ;
Clinical Infectious Diseases; Vol. 74; No. 9; 1525-1533; PMCID
PMC9070832; 10.1093/cid/ciab686
Cable, Jennifer; Rappuoli, Rino; et el. (2022) Innovative
vaccine approaches—a Keystone Symposia report ; Annals of the New
York Academy of Sciences; Vol. 1511; No. 1; 59-86; 10.1111/nyas.14739
Needham, Brittany D.; Funabashi, Masanori; et el. (2022) A
gut-derived metabolite alters brain activity and anxiety behaviour in
mice ; Nature; Vol. 602; No. 7899; 647-653; PMCID PMC9170029; 10.1038/s41586-022-04396-8
Weber, Timm; Potthoff, Julian; et el. (2022) Analysis
of antibodies from HCV elite neutralizers identifies genetic
determinants of broad neutralization ; Immunity; Vol. 55; No. 2;
341-354; PMCID PMC10089621; 10.1016/j.immuni.2021.12.003
Yang, Zhi; Dam, Kim-Marie A.; et el. (2022) Neutralizing
antibodies induced in immunized macaques recognize the CD4-binding site
on an occluded-open HIV-1 envelope trimer ; Nature Communications;
Vol. 13; Art. No. 732; PMCID PMC8826976; 10.1038/s41467-022-28424-3
Tanaka, Shiho; Olson, C. Anders; et el. (2022) Rapid
identification of neutralizing antibodies against SARS-CoV-2 variants by
mRNA display ; Cell Reports; Vol. 38; No. 6; Art. No. 110348; PMCID
PMC8769934; 10.1016/j.celrep.2022.110348
Vanshylla, Kanika; Fan, Chengcheng; et el. (2022) Discovery
of ultrapotent broadly neutralizing antibodies from SARS-CoV-2 elite
neutralizers ; Cell Host and Microbe; Vol. 30; No. 1; 69-82; PMCID
PMC8683262; 10.1016/j.chom.2021.12.010
Ogega, Clinton O.; Skinner, Nicole E.; et el. (2022) B
cell overexpression of FCRL5 and PD-1 is associated with low antibody
titers in HCV infection ; PLOS Pathogens; Vol. 18; No. 1; Art.
No. e1010179; PMCID PMC8769295; 10.1371/journal.ppat.1010179
Barnes, Christopher; Scheid, Johannes F.; et el. (2021) Structural
insights into antibody-mediated neutralization of SARS-CoV-2 ;
Glycobiology; Vol. 31; No. 12; 1696-1697; 10.1093/glycob/cwab121
Escolano, Amelia; Gristick, Harry B.; et el. (2021) Sequential
immunization of macaques elicits heterologous neutralizing antibodies
targeting the V3-glycan patch of HIV-1 Env ; Science Translational
Medicine; Vol. 13; No. 621; Art. No. abk1533; PMCID PMC8932345; 10.1126/scitranslmed.abk1533
Brune, Karl D.; Liekniņa, Ilva; et el. (2021) N-Terminal
Modification of Gly-His-Tagged Proteins with Azidogluconolactone ;
ChemBioChem; Vol. 22; No. 22; 3199-3207; 10.1002/cbic.202100381
Woodward, Denise; Ricks, Ernest, Jr.; et el. (2021) The
Path of Science in Future Tibetan Buddhist Education ; Frontiers in
Communication; Vol. 6; Art. No. 731604; 10.3389/fcomm.2021.731604
Abernathy, Morgan E.; Gristick, Harry B.; et el. (2021) Antibody
elicited by HIV-1 immunogen vaccination in macaques displaces Env fusion
peptide and destroys a neutralizing epitope ; npj Vaccines; Vol. 6;
Art. No. 126; PMCID PMC8545924; 10.1038/s41541-021-00387-4
Abernathy, Morgan E.; Dam, Kim-Marie A.; et el. (2021) How
Antibodies Recognize Pathogenic Viruses: Structural Correlates of
Antibody Neutralization of HIV-1, SARS-CoV-2, and Zika ; Viruses;
Vol. 13; No. 10; Art. No. 2106; PMCID PMC8537525; 10.3390/v13102106
Jette, Claudia A.; Cohen, Alexander A.; et el. (2021) Broad
cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19
donor-derived neutralizing antibodies ; Cell Reports; Vol. 36;
No. 13; Art. No. 109760; PMCID PMC8423902; 10.1016/j.celrep.2021.109760
Ullah, Irfan; Prévost, Jérémie; et el. (2021) Live
imaging of SARS-CoV-2 infection in mice reveals that neutralizing
antibodies require Fc function for optimal efficacy ; Immunity; Vol.
54; No. 9; 2143-2158; PMCID PMC8372518; 10.1016/j.immuni.2021.08.015
Muecksch, Frauke; Weisblum, Yiska; et el. (2021) Affinity
maturation of SARS-CoV-2 neutralizing antibodies confers potency,
breadth, and resilience to viral escape mutations ; Immunity; Vol.
54; No. 8; 1853-1868; PMCID PMC8323339; 10.1016/j.immuni.2021.07.008
West, Anthony P., Jr.; Wertheim, Joel O.; et el. (2021) Detection
and characterization of the SARS-CoV-2 lineage B.1.526 in New York ;
Nature Communications; Vol. 12; Art. No. 4886; PMCID PMC8352861; 10.1038/s41467-021-25168-4
Hensley, Matthew K.; Bain, William G.; et el. (2021) Intractable
Coronavirus Disease 2019 (COVID-19) and Prolonged Severe Acute
Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Replication in a
Chimeric Antigen Receptor-Modified T-Cell Therapy Recipient: A Case
Study ; Clinical Infectious Diseases; Vol. 73; No. 3; e815-e821;
PMCID PMC7929077; 10.1093/cid/ciab072
Bjorkman, Pamela (2021) Neutralizing
antibodies against coronaviruses ; Microscopy and Microanalysis; Vol.
27; No. S1; 1112-1113; 10.1017/s1431927621004177
Garber, Arkadiy I.; Kupper, Maria; et el. (2021) The
Evolution of Interdependence in a Four-Way Mealybug Symbiosis ;
Genome Biology and Evolution; Vol. 13; No. 8; Art. No. evab123; PMCID
PMC8331144; 10.1093/gbe/evab123
Greaney, Allison J.; Starr, Tyler N.; et el. (2021) Mapping
mutations to the SARS-CoV-2 RBD that escape binding by different classes
of antibodies ; Nature Communications; Vol. 12; Art. No. 4196; PMCID
PMC8263750; 10.1038/s41467-021-24435-8
Haugh, Kelsey A.; Ladinsky, Mark S.; et el. (2021) In
vivo imaging of retrovirus infection reveals a role for Siglec-1/CD169
in multiple routes of transmission ; eLife; Vol. 10; Art. No. e64179;
PMCID PMC8298093; 10.7554/eLife.64179
Hoffmann, Magnus A. G.; Kieffer, Collin; et el. (2021) In
vitro characterization of engineered red blood cells as viral traps
against HIV-1 and SARS-CoV-2 ; Molecular Therapy - Methods and
Clinical Development; Vol. 21; 161-170; PMCID PMC7944778; 10.1016/j.omtm.2021.03.003
Scheid, Johannes F.; Barnes, Christopher O.; et el. (2021) B
cell genomics behind cross-neutralization of SARS-CoV-2 variants and
SARS-CoV ; Cell; Vol. 184; No. 12; 3205-3221; PMCID PMC8064835; 10.1016/j.cell.2021.04.032
Livanos, Alexandra E.; Jha, Divya; et el. (2021) Intestinal
Host Response to SARS-CoV-2 Infection and COVID-19 Outcomes in Patients
With Gastrointestinal Symptoms ; Gastroenterology; Vol. 160; No. 7;
2435-2450; PMCID PMC7931673; 10.1053/j.gastro.2021.02.056
De Gasparo, Raoul; Pedotti, Mattia; et el. (2021) Bispecific
IgG neutralizes SARS-CoV-2 variants and prevents escape in mice ;
Nature; Vol. 593; No. 7859; 424-428; PMCID PMC8330819; 10.1038/s41586-021-03461-y
Bloom, Jesse D.; Chan, Yujia Alina; et el. (2021) Investigate
the origins of COVID-19 ; Science; Vol. 372; No. 6543; 694; PMCID
PMC9520851; 10.1126/science.abj0016
Agudelo, Marianna; Palus, Martin; et el. (2021) Broad
and potent neutralizing human antibodies to tick-borne flaviviruses
protect mice from disease ; Journal of Experimental Medicine; Vol.
218; No. 5; Art. No. e20210236; PMCID PMC8040517; 10.1084/jem.20210236
Wang, Zijun; Schmidt, Fabian; et el. (2021) mRNA
vaccine-elicited antibodies to SARS-CoV-2 and circulating variants ;
Nature; Vol. 592; No. 7855; 616-622; PMCID PMC7836122; 10.1038/s41586-021-03324-6
Jette, Claudia A.; Barnes, Christopher O.; et el. (2021) Cryo-EM
structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1
adopt a CD4-bound open conformation ; Nature Communications; Vol. 12;
Art. No. 1950; PMCID PMC8007822; 10.1038/s41467-021-21816-x
Gaebler, Christian; Wang, Zijun; et el. (2021) Evolution
of antibody immunity to SARS-CoV-2 ; Nature; Vol. 591; No. 7851;
639-644; PMCID PMC8221082; 10.1038/s41586-021-03207-w
Cohen, Alexander A.; Yang, Zhi; et el. (2021) Construction,
characterization, and immunization of nanoparticles that display a
diverse array of influenza HA trimers ; PLoS ONE; Vol. 16; No. 3;
Art. No. e0247963; PMCID PMC7932532; 10.1371/journal.pone.0247963
Bain, William G.; Peñaloza, Hernán F.; et el. (2021) Lower
Respiratory Tract Myeloid Cells Harbor SARS-Cov-2 and Display an
Inflammatory Phenotype ; CHEST; Vol. 159; No. 3; 963-966; PMCID
PMC7671922; 10.1016/j.chest.2020.10.083
Cohen, Alexander A.; Gnanapragasam, Priyanthi N. P.; et el. (2021)
Mosaic
nanoparticles elicit cross-reactive immune responses to zoonotic
coronaviruses in mice ; Science; Vol. 371; No. 6530; 735-741; PMCID
PMC7928838; 10.1126/science.abf6840
Esswein, Shannon R. and Bjorkman, Pamela J. (2021) Structural
Basis for Germline Antibody Binding to Zika Virus Envelope Domain
III ; Biophysical Journal; Vol. 120; No. 3; 276A-277A; 10.1016/j.bpj.2020.11.1760
Bárcena, Montserrat; Barnes, Christopher O.; et el. (2021) Structural
biology in the fight against COVID-19 ; Nature Structural &
Molecular Biology; Vol. 28; No. 1; 2-7; 10.1038/s41594-020-00544-8
Barnes, Christopher O.; Jette, Claudia A.; et el. (2020) SARS-CoV-2
neutralizing antibody structures inform therapeutic strategies ;
Nature; Vol. 588; No. 7839; 682-687; PMCID PMC8092461; 10.1038/s41586-020-2852-1
Linsky, Thomas W.; Vergara, Renan; et el. (2020) De
novo design of potent and resilient hACE2 decoys to neutralize
SARS-CoV-2 ; Science; Vol. 370; No. 6521; 1208-1214; PMCID
PMC7920261; 10.1126/science.abe0075
Wang, Zijun; Barnes, Christopher O.; et el. (2020) A
broadly neutralizing macaque monoclonal antibody against the HIV-1
V3-Glycan patch ; eLife; Vol. 9; Art. No. e61991; PMCID PMC7577740;
10.7554/eLife.61991
Robbiani, Davide F.; Gaebler, Christian; et el. (2020) Convergent
Antibody Responses to SARS-CoV-2 Infection in Convalescent
Individuals ; Nature; Vol. 584; No. 7821; 437-442; PMCID PMC7263513;
10.1038/s41586-020-2456-9
Barnes, Christopher O.; West, Anthony P., Jr.; et el. (2020) Structures
of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and
Recurrent Features of Antibodies ; Cell; Vol. 182; No. 4; 828-842;
PMCID PMC7311918; 10.1016/j.cell.2020.06.025
Hoffmann, Magnus A. G.; Bar-On, Yotam; et el. (2020) Nanoparticles
presenting clusters of CD4 expose a universal vulnerability of HIV-1 by
mimicking target cells ; Proceedings of the National Academy of
Sciences of the United States of America; Vol. 117; No. 31; 18719-18728;
PMCID PMC7414181; 10.1073/pnas.2010320117
Ladinsky, Mark S.; Gnanapragasam, Priyanthi N. P.; et el. (2020) Electron
tomography visualization of HIV-1 fusion with target cells using fusion
inhibitors to trap the pre-hairpin intermediate ; eLife; Vol. 9; Art.
No. e58411; PMCID PMC7394545; 10.7554/eLife.58411
Esswein, Shannon R.; Gristick, Harry B.; et el. (2020) Structural
basis for Zika envelope domain III recognition by a germline version of
a recurrent neutralizing antibody ; Proceedings of the National
Academy of Sciences of the United States of America; Vol. 117; No. 18;
9865-9875; PMCID PMC7211955; 10.1073/pnas.1919269117
Li, Shirley; Kujawski, Maciej; et el. (2020) Use
of Click-Chemistry to Make Bivalent Antibodies for Redirection of T
Cells: Proof of Concept in an In Vitro HIV Model ; Molecular Therapy;
Vol. 28; No. 4; 369; 10.1016/j.ymthe.2020.04.019
Van Rompay, Koen K. A.; Coffey, Lark L.; et el. (2020) A
Combination of Two Human Monoclonal Antibodies Limits Fetal Damage by
Zika Virus in Macaques ; Proceedings of the National Academy of
Sciences of the United States of America; Vol. 117; No. 14; 7981-7989;
PMCID PMC7149495; 10.1073/pnas.2000414117
Flyak, Andrew I.; Ruiz, Stormy E.; et el. (2020) An
ultralong CDRH2 in HCV neutralizing antibody demonstrates structural
plasticity of antibodies against E2 glycoprotein ; eLife; Vol. 9;
Art. No. e53169; PMCID PMC7064334; 10.7554/elife.53169
Schommers, Philipp; Gruell, Henning; et el. (2020) Restriction
of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody ;
Cell; Vol. 180; No. 3; 471-489; PMCID PMC7042716; 10.1016/j.cell.2020.01.010
Bjorkman, Pamela J. (2020) Can
we use structural knowledge to design a protective vaccine against
HIV-1? ; HLA; Vol. 95; No. 2; 95-103; 10.1111/tan.13759
Yang, Zhi; Wang, Haoqing; et el. (2019) Asymmetric
opening of HIV-1 Env bound to CD4 and a coreceptor-mimicking
antibody ; Nature Structural & Molecular Biology; Vol. 26;
No. 12; 1167-1175; 10.1038/s41594-019-0344-5
Einav, Tal; Yazdi, Shahrzad; et el. (2019) Harnessing
Avidity: Quantifying the Entropic and Energetic Effects of Linker Length
and Rigidity for Multivalent Binding of Antibodies to HIV-1 ; Cell
Systems; Vol. 9; No. 5; 466-474; PMCID PMC6892280; 10.1016/j.cels.2019.09.007
Schommers, P.; Gruell, H.; et el. (2019) Novel
highly potent CD4bs bNAb with restricted pathway to HIV-1 escape ;
HIV Medicine; Vol. 20; No. S9; 50; 10.1111/hiv.12814
Ladinsky, Mark S.; Khamaikawin, Wannisa; et el. (2019) Mechanisms
of virus dissemination in bone marrow of HIV-1-infected humanized BLT
mice ; eLife; Vol. 8; Art. No. e46916; PMCID PMC6839903; 10.7554/elife.46916
Bublitz, DeAnna C.; Chadwick, Grayson L.; et el. (2019) Peptidoglycan
Production by an Insect-Bacterial Mosaic ; Cell; Vol. 179; No. 3;
703-712; PMCID PMC6838666; 10.1016/j.cell.2019.08.054
Escolano, Amelia; West, Anthony P., Jr.; et el. (2019) Immunization
expands B cells specific to HIV-1 V3 glycan in mice and macaques ;
Nature; Vol. 570; No. 7762; 468-473; PMCID PMC6657810; 10.1038/s41586-019-1250-z
Schoofs, Till; Barnes, Christopher O.; et el. (2019) Broad
and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV
Envelope ; Immunity; Vol. 50; No. 6; 1513-1529; PMCID PMC6591006; 10.1016/j.immuni.2019.04.014
Ladinsky, Mark S.; Araujo, Leandro P.; et el. (2019) Endocytosis
of commensal antigens by intestinal epithelial cells regulates mucosal T
cell homeostasis ; Science; Vol. 363; No. 6431; Art. No. eaat4042;
PMCID PMC6708280; 10.1126/science.aat4042
Uchil, Pradeep D.; Pi, Ruoxi; et el. (2019) A
Protective Role for the Lectin CD169/Siglec-1 against a Pathogenic
Murine Retrovirus ; Cell Host & Microbe; Vol. 25; No. 1; 87-100;
PMCID PMC6331384; 10.1016/j.chom.2018.11.011
Kinchen, Valerie J.; Zahid, Muhammad N.; et el. (2018) Broadly
Neutralizing Antibody Mediated Clearance of Human Hepatitis C Virus
Infection ; Cell Host & Microbe; Vol. 24; No. 5; 717-730; PMCID
PMC6250073; 10.1016/j.chom.2018.10.012
Flyak, Andrew I.; Ruiz, Stormy; et el. (2018) HCV
Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize
an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design ;
Cell Host & Microbe; Vol. 24; No. 5; 703-716; PMCID PMC6258177; 10.1016/j.chom.2018.10.009
Keeffe, Jennifer R.; Van Rompay, Koen K. A.; et el. (2018) A
Combination of Two Human Monoclonal Antibodies Prevents Zika Virus
Escape Mutations in Non-human Primates ; Cell Reports; Vol. 25;
No. 6; 1385-1394; PMCID PMC6268006; 10.1016/j.celrep.2018.10.031
Wang, Haoqing; Barnes, Christopher O.; et el. (2018) Partially
Open HIV-1 Envelope Structures Exhibit Conformational Changes Relevant
for Coreceptor Binding and Fusion ; Cell Host & Microbe; Vol. 24;
No. 4; 579-592; PMCID PMC6185872; 10.1016/j.chom.2018.09.003
Barnes, Christopher O.; Wang, Haoqing; et el. (2018) A
Co-receptor-mimicking Antibody Stabilizes the Displaced V1V2 Loops in a
Partially Open sCD4-bound HIV-1 Envelope Complex ; AIDS Research and
Human Retroviruses; Vol. 34; No. S1; 131; 10.1089/aid.2018.5000.abstracts
Gristick, Harry; van Schooten, Jelle; et el. (2018) Engineering
HIV Immunogens to Elicit IOMA-like Antibodies Targeting the CD4 Binding
Site ; AIDS Research and Human Retroviruses; Vol. 34; No. S1; 59; 10.1089/aid.2018.5000.abstracts
Escolano, Amelia; Gristick, Harry B.; et el. (2018) Sequential
Immunization Strategies to Elicit HIV-1 bNAbs in Animal Models With a
Polyclonal B Cell Repertoire ; AIDS Research and Human Retroviruses;
Vol. 34; No. S1; 331; 10.1089/aid.2018.5000.abstracts
Mendoza, Pilar; West, Anthony P., Jr.; et el. (2018) Combination
therapy with anti-HIV-1 antibodies maintains viral suppression ;
Nature; Vol. 561; No. 7724; 479-484; PMCID PMC6166473; 10.1038/s41586-018-0531-2
Stadtmueller, Beth M.; Bridges, Michael D.; et el. (2018) DEER
Spectroscopy Measurements Reveal Multiple Conformations of HIV-1 SOSIP
Envelopes that Show Similarities with Envelopes on Native Virions ;
Immunity; Vol. 49; No. 2; 235-246; PMCID PMC6104740; 10.1016/j.immuni.2018.06.017
Donaldson, G. P.; Ladinsky, M. S.; et el. (2018) Gut
microbiota utilize immunoglobulin A for mucosal colonization ;
Science; Vol. 360; No. 6390; 795-800; PMCID PMC5973787; 10.1126/science.aaq0926
Barnes, Christopher O.; Gristick, Harry B.; et el. (2018) Structural
characterization of a highly-potent V3-glycan broadly neutralizing
antibody bound to natively-glycosylated HIV-1 envelope ; Nature
Communications; Vol. 9; Art. No. 1251; PMCID PMC5871869; 10.1038/s41467-018-03632-y
Kieffer, Collin; Ladinsky, Mark S.; et el. (2017) Multiscale
imaging of HIV-1 transmission in humanized mice ; AIDS Research and
Human Retroviruses; Vol. 33; No. S1; S6-S7; PMCID PMC5685215; 10.1089/AID.2017.0142
Gristick, Harry B.; Wang, Haoqing; et el. (2017) X-ray
and EM structures of a natively glycosylated HIV-1 envelope trimer ;
Acta Crystallographica Section D Structural Biology; Vol. 73; No. 10;
822-828; PMCID PMC5633907; 10.1107/S2059798317013353
Greider, Carol and Bjorkman, Pamela (2017) Not
just Salk ; Science; Vol. 357; No. 6356; 1105-1106; 10.1126/science.aao6221
Chiuppesi, Flavia; Wussow, Felix; et el. (2017) Comparison
of homologous and heterologous prime-boost vaccine approaches using
Modified Vaccinia Ankara and soluble protein to induce neutralizing
antibodies by the human cytomegalovirus pentamer complex in mice ;
PLoS ONE; Vol. 12; No. 8; Art. No. e0183377; PMCID PMC5558987; 10.1371/journal.pone.0183377
Wang, Haoqing; Gristick, Harry B.; et el. (2017) Asymmetric
recognition of HIV-1 Envelope trimer by V1V2 loop-targeting
antibodies ; eLife; Vol. 6; Art. No. e27389; PMCID PMC5472438; 10.7554/eLife.27389.001
Robbiani, Davide F.; Khouri, Ricardo; et el. (2017) Recurrent
Potent Human Neutralizing Antibodies to Zika Virus in Brazil and
Mexico ; Cell; Vol. 169; No. 4; 597-609; PMCID PMC5492969; 10.1016/j.cell.2017.04.024
Gu, Mingyu; Lajoie, Dollie; et el. (2017) LEM2
recruits CHMP7 for ESCRT-mediated nuclear envelope closure in fission
yeast and human cells ; Proceedings of the National Academy of
Sciences of the United States of America; Vol. 114; No. 11; E2166-E2175;
PMCID PMC5358359; 10.1073/pnas.1613916114
Kieffer, Collin; Ladinsky, Mark S.; et el. (2017) Longitudinal
imaging of HIV-1 spread in humanized mice with parallel 3D
immunofluorescence and electron tomography ; eLife; Vol. 6; Art.
No. e23282; PMCID PMC5338924; 10.7554/eLife.23282
Caskey, Marina; West, Anthony P., Jr.; et el. (2017) Antibody
10-1074 suppresses viremia in HIV-1-infected individuals ; Nature
Medicine; Vol. 23; No. 2; 185-191; PMCID PMC5467219; 10.1038/nm.4268
Freund, Natalia T.; Wang, Haoqing; et el. (2017) Coexistence
of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive
viruses in a viremic controller ; Science Translational Medicine;
Vol. 9; No. 373; Art. No. aal2144; PMCID PMC5467220; 10.1126/scitranslmed.aal2144
Gu, M.; Chen, O. S.; et el. (2016) Lem2p
(LEM2) and Cmp7p (CHMP7) function in ESCRT-dependent nuclear envelope
remodeling in fission yeast ; Molecular Biology of the Cell; Vol. 27;
Art. No. P498
Gu, M.; LaJoie, D.; et el. (2016) Non-Canonical
ESCRT Structures and Functions ; Molecular Biology of the Cell; Vol.
27; No. 25; M191; 10.1091/mbc.E16-10-0736
Wang, Haoqing; Cohen, Alexander A.; et el. (2016) Cryo-EM
structure of a CD4-bound open HIV-1 envelope trimer reveals structural
rearrangements of the gp120 V1V2 loop ; Proceedings of the National
Academy of Sciences of the United States of America; Vol. 113; No. 46;
E7151-E7158; PMCID PMC5135367; 10.1073/pnas.1615939113
Owens, Gwen E.; New, Danielle M.; et el. (2016) Comparative
analysis of anti-polyglutamine Fab crystals grown on Earth and in
microgravity ; Acta Crystallographica Section F: Structural Biology
and Crystallization Communications; Vol. 72; No. 10; 762-771; PMCID
PMC5053161; 10.1107/S2053230X16014011
Gristick, Harry B.; von Boehmer, Lotta; et el. (2016) Natively
glycosylated HIV-1 Env structure reveals new mode for antibody
recognition of the CD4-binding site ; Nature Structural &
Molecular Biology; Vol. 23; No. 10; 906-915; PMCID PMC5127623; 10.1038/nsmb.3291
Gristick, Harry; von Boehmer, Lotta; et el. (2016) Structure
of a Natively-glycosylated HIV-1 Env Reveals a New Mode for VH1-2
Antibody Recognition of the CD4 Binding Site Relevant to Vaccine
Design ; AIDS Research and Human Retroviruses; Vol. 32; No. Suppl. 1;
62
Stadtmueller, Beth M.; Yang, Zhongyu; et el. (2016) Biophysical
and Biochemical Characterization of Avian Secretory Component Provides
Structural Insights into the Evolution of the Polymeric Ig Receptor ;
Journal of Immunology; Vol. 197; No. 4; 1408-1414; PMCID PMC4976031; 10.4049/jimmunol.1600463
Scheid, Johannes F.; West, Anthony P., Jr.; et el. (2016) HIV-1
antibody 3BNC117 suppresses viral rebound in humans during treatment
interruption ; Nature; Vol. 535; No. 7613; 556-560; PMCID PMC5034582;
10.1038/nature18929
Schoofs, Till; Klein, Florian; et el. (2016) HIV-1
therapy with monoclonal antibody 3BNC117 elicits host immune responses
against HIV-1 ; Science; Vol. 352; No. 6288; 997-1001; PMCID
PMC5151174; 10.1126/science.aaf0972
Ahmed, Alysia A.; Keremane, Sravya R.; et el. (2016) Structural
characterization of GASDALIE Fc bound to the activating Fc receptor
FcγRIIIa ; Journal of Structural Biology; Vol. 194; No. 1; 78-89;
PMCID PMC4769027; 10.1016/j.jsb.2016.02.001
Scharf, Louise; West, Anthony P. , Jr.; et el. (2016) Structural
basis for germline antibody recognition of HIV-1 immunogens ; eLife;
Vol. 5; Art. No. e13783; PMCID PMC4811768; 10.7554/eLife.13783
Stadtmueller, Beth M.; Huey-Tubman, Kathryn E.; et el. (2016) The
structure and dynamics of secretory component and its interactions with
polymeric immunoglobulins ; eLife; Vol. 5; Art. No. e10640; PMCID
PMC4786434; 10.7554/eLife.10640
Morgand, Marion; Bouvin-Pley, Mélanie; et el. (2016) V1/V2
Neutralizing Epitope is Conserved in Divergent Non-M Groups of
HIV-1 ; Journal of Acquired Immune Deficiency Syndromes; Vol. 71;
No. 3; 237-245; PMCID PMC4770367; 10.1097/QAI.0000000000000854
Ndjamen, Blaise; Joshi, Devashish S.; et el. (2016) Characterization
of Antibody Bipolar Bridging Mediated by the Human Cytomegalovirus Fc
receptor gp68 ; Journal of Virology; Vol. 90; No. 6; 3262-3567; PMCID
PMC4810659; 10.1128/JVI.02855-15
Ding, Shilei; Veillete, Maxime; et el. (2016) A
Highly-Conserved Residue of the HIV-1-gp120 Inner Domain is Important
for ADCC Responses Mediated by Anti-Cluster A Antibodies ; Journal of
Virology; Vol. 90; No. 4; 2127-2134; PMCID PMC4733974; 10.1128/JVI.02779-15
Davenport, Yunji W.; West, Anthony P.; et el. (2016) Structure
of an HIV-2 gp120 in complex with CD4 ; Journal of Virology; Vol. 90;
No. 4; 2112-2118; PMCID PMC4733984; 10.1128/JVI.02678-15
Treweek, Jennifer B.; Chan, Ken Y.; et el. (2015) Whole-body
tissue stabilization and selective extractions via tissue-hydrogel
hybrids for high-resolution intact circuit mapping and phenotyping ;
Nature Protocols; Vol. 10; No. 11; 1860-1896; PMCID PMC4917295; 10.1038/nprot.2015.122
Sewald, Xaver; Ladinsky, Mark S.; et el. (2015) Retroviruses
use CD169-mediated trans-infection of permissive lymphocytes to
establish infection ; Science; Vol. 350; No. 6260; 563-567; PMCID
PMC4651917; 10.1126/science.aab2749
Freund, Natalia T.; Horwitz, Joshua A.; et el. (2015) A
New Glycan-Dependent CD4-Binding Site Neutralizing Antibody Exerts
Pressure on HIV-1 In Vivo ; PLoS Pathogens; Vol. 11; No. 10; Art.
No. e1005238; PMCID PMC4627763; 10.1371/journal.ppat.1005238
Scharf, Louise; Wang, Haoqing; et el. (2015) Broadly
Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1
Env ; Cell; Vol. 162; No. 6; 1379-1390; PMCID PMC4587768; 10.1016/j.cell.2015.08.035
Owens, Gwen E.; New, Danielle M.; et el. (2015) Anti-polyQ
antibodies recognize a short polyQ stretch in both normal and mutant
huntingtin exon 1 ; Journal of Molecular Biology; Vol. 427; No. 15;
2507-2519; PMCID PMC4520773; 10.1016/j.jmb.2015.05.023
Yoon, Hyejin; Macke, Jennifer; et el. (2015) CATNAP:
a tool to compile, analyze and tally neutralizing antibody panels ;
Nucleic Acids Research; Vol. 43; No. W1; W213-W219; PMCID PMC4489231; 10.1093/nar/gkv404
Dosenovic, Pia; von Boehmer, Lotta; et el. (2015) Immunization
for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice ;
Cell; Vol. 161; No. 7; 1505-1515; PMCID PMC4604566; 10.1016/j.cell.2015.06.003
Zhou, Tongqing; West, Anthony P., Jr.; et el. (2015) Structural
Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite
in 14 Donors ; Cell; Vol. 161; No. 6; 1280-1292; PMCID PMC4683157; 10.1016/j.cell.2015.05.007
Sievers, Stuart A.; Scharf, Louise; et el. (2015) Antibody
engineering for increased potency, breadth and half-life ; Current
Opinion in HIV and AIDS; Vol. 10; No. 3; 151-159; PMCID PMC4465343; 10.1097/COH.0000000000000148
Ndjamen, Blaise and Bjorkman, Pamela (2015) Distinct
Intracellular Trafficking Patterns of Host IgG by Herpes Virus
Fc-Receptors ; FASEB Journal; Vol. 29; No. S1; Art. No. 574.30
Barbian, Hannah J.; Galimidi, Rachel P.; et el. (2015) Neutralization
Properties of Simian Immunodeficiency Viruses Infecting Chimpanzees and
Gorillas ; mBio; Vol. 6; No. 2; Art. No. e00296; PMCID PMC4453581; 10.1128/mBio.00296-15
Galimidi, Rachel P.; Klein, Joshua S.; et el. (2015) Intra-Spike
Crosslinking Overcomes Antibody Evasion by HIV-1 ; Cell; Vol. 160;
No. 3; 433-446; PMCID PMC4401576; 10.1016/j.cell.2015.01.016
Wu, Yunji and Bjorkman, Pamela J. (2015) Structural
Basis for Enhanced Hiv-1 Neutralization by a Dimeric Immunoglobulin G
Form of the Glycan-Recognizing Antibody 2G12 ; Biophysical Journal;
Vol. 108; No. 2; 374A; 10.1016/j.bpj.2014.11.2053
Bjorkman, Pamela J. (2015) Not
Second Class: The First Class II MHC Crystal Structure ; Journal of
Immunology; Vol. 194; No. 1; 3-4; 10.4049/jimmunol.1402828
Bouvin-Pley, M.; Morgand, M.; et el. (2014) Drift
of the HIV-1 envelope glycoprotein gp120 toward increased neutralization
resistance over the course of the epidemic: a comprehensive study using
the most potent and broadly neutralizing monoclonal antibodies ;
Journal of Virology; Vol. 88; No. 23; 13910-13917; PMCID PMC4248973; 10.1128/JVI.02083-14
Klein, Florian; Nogueira, Lilian; et el. (2014) Enhanced
HIV-1 immunotherapy by commonly arising antibodies that target virus
escape variants ; Journal of Experimental Medicine; Vol. 211; No. 12;
2361-2372; PMCID PMC4235636; 10.1084/jem.20141050
Bouvin-Pley, Mélanie; Morgand, Marion; et el. (2014) Adaptation
of HIV-1 Envelope Glycoprotein gp120 to Humoral Immunity over the Course
of the Epidemic ; AIDS Research and Human Retroviruses; Vol. 30;
No. S1; A224; 10.1089/aid.2014.5490.abstract
Sievers, Stuart A.; Patel, Sonal N.; et el. (2014) Engineering
Antibodies to Enhance Activity and Increase Half-life ; AIDS Research
and Human Retroviruses; Vol. 30; No. S1; A210; 10.1089/aid.2014.5456.abstract
Klein, Joshua S.; Jiang, Siduo; et el. (2014) Design
and characterization of structured protein linkers with differing
flexibilities ; Protein Engineering, Design and Selection; Vol. 27;
No. 10; 325-330; PMCID PMC4191447; 10.1093/protein/gzu043
Nishimura, Yoshiaki; Shingai, Masashi; et el. (2014) Preexposure
passive transfer predicts plasma antibody levels prevent HIV-I
aquisition ; Journal of Medical Primatology; Vol. 43; No. 5; 378; 10.1111/jmp.12150
Shingai, Masashi and Bjorkman, Pamela J. (2014) Passive
transfer of modest titers of potent and broadly neutralizing anti-HIV
monoclonal antibodies block SHIV infection in macaques ; Journal of
Experimental Medicine; Vol. 211; No. 10; 2061-2074; PMCID PMC4172223; 10.1084/jem.20132494
Ahmed, Alysia A.; Giddens, John; et el. (2014) Structural
characterization of anti-inflammatory Immunoglobulin G Fc proteins ;
Journal of Molecular Biology; Vol. 426; No. 18; 3166-3179; PMCID
PMC4159253; 10.1016/j.jmb.2014.07.006
Bjorkman, Pamela (2014) Engineering
Improved Antibodies Against HIV ; Protein Science; Vol. 23; No. S1;
62-63; 10.1002/pro.2504
Scharf, Louise; Scheid, Johannes F.; et el. (2014) Antibody
8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope
Spike ; Cell Reports; Vol. 7; No. 3; 785-795; PMCID PMC4109818; 10.1016/j.celrep.2014.04.001
Ndjamen, Blaise; Farley, Alexander H.; et el. (2014) The
Herpes Virus Fc Receptor gE-gI Mediates Antibody Bipolar Bridging to
Clear Viral Antigens from the Cell Surface ; PLoS Pathogens; Vol. 10;
No. 3; Art. No. e1003961; PMCID PMC3946383; 10.1371/journal.ppat.1003961
West, Anthony P., Jr.; Scharf, Louise; et el. (2014) Structural
Insights on the Role of Antibodies in HIV-1 Vaccine and Therapy ;
Cell; Vol. 156; No. 4; 633-648; PMCID PMC4041625; 10.1016/j.cell.2014.01.052
Ladinsky, Mark S.; Kieffer, Collin; et el. (2014) Electron
Tomography of HIV-1 Infection in Gut-Associated Lymphoid Tissue ;
PLoS Pathogens; Vol. 10; No. 1; Art. No. e1003899; PMCID PMC3907528; 10.1371/journal.ppat.1003899
Wu, Yunji; West, Anthony P., Jr.; et el. (2013) Structural
Basis for Enhanced HIV-1 Neutralization by a Dimeric Immunoglobulin G
Form of the Glycan-Recognizing Antibody 2G12 ; Cell Reports; Vol. 5;
No. 5; 1443-1455; PMCID PMC3919625; 10.1016/j.celrep.2013.11.015
West, A. P., Jr.; Scharf, L.; et el. (2013) Computational
Analysis of Anti-HIV-1 Antibody Neutralization Panel Data to Identify
Potential Functional Epitope Residues ; AIDS Research and Human
Retroviruses; Vol. 29; No. 11; A170; 10.1089/aid.2013.1500
Scharf, L.; West, A. P.; et el. (2013) Structural
Basis for HIV-1 gp120 Recognition by a Germ-line Version of a Broadly
Neutralizing Antibody ; AIDS Research and Human Retroviruses; Vol.
29; No. 11; A11-A12; 10.1089/aid.2013.1500
Galimidi, R. P.; West, A. P.; et el. (2013) Thwarting
HIV Evasion of Antibody Avidity with Novel Antibody Architectures ;
AIDS Research and Human Retroviruses; Vol. 29; No. 11; A140-A141; 10.1089/aid.2013.1500
Horwitz, Joshua A.; Halper-Stromberg, Ariel; et el. (2013) HIV-1
suppression and durable control by combining single broadly neutralizing
antibodies and antiretroviral drugs in humanized mice ; Proceedings
of the National Academy of Sciences of the United States of America;
Vol. 110; No. 41; 16538-16543; PMCID PMC3799352; 10.1073/pnas.1315295110
West, Anthony P., Jr.; Scharf, Louise; et el. (2013) Computational
analysis of anti-HIV-1 antibody neutralization panel data to identify
potential functional epitope residues ; Proceedings of the National
Academy of Sciences of the United States of America; Vol. 110; No. 26;
10598-10603; PMCID PMC3696754; 10.1073/pnas.1309215110
Diskin, Ron; Klein, Florian; et el. (2013) Restricting
HIV-1 pathways for escape using rationally designed anti–HIV-1
antibodies ; Journal of Experimental Medicine; Vol. 210; No. 6;
1235-1249; PMCID PMC3674693; 10.1084/jem.20130221
Galimidi, Rachel; West, Anthony; et el. (2013) Thwarting
HIV evasion of antibody avidity with novel antibody architectures ;
Journal of Immunology; Vol. 190; 179.7
Parrish, Nicholas F.; Galimidi, Rachel P.; et el. (2013) Phenotypic
properties of transmitted founder HIV-1 ; Proceedings of the National
Academy of Sciences of the United States of America; Vol. 110; No. 17;
6626-6633; PMCID PMC3637789; 10.1073/pnas.1304288110
Scharf, Louise; West, Anthony P., Jr.; et el. (2013) Structural
basis for HIV-1 gp120 recognition by a germ-line version of a broadly
neutralizing antibody ; Proceedings of the National Academy of
Sciences of the United States of America; Vol. 110; No. 15; 6049-6054;
PMCID PMC3625305; 10.1073/pnas.1303682110
Ndjamen, Blaise; Farley, Alexander; et el. (2013) Intracellular
Trafficking of an Antibody Bipolar Bridged Complex of HSV-1 gE-gI, IgG,
and a Viral Antigen ; FASEB Journal; Vol. 27; Art. No. 767.3
Diskin, Ron; Sather, D. Noah; et el. (2013) Overcoming
HIV pathways for escape using rationally-designed anti-HIV
antibodies ; Journal of Acquired Immune Deficiency Syndromes; Vol.
62; No. S1; 49-49; 10.1097/01.qai.0000429234.07501.af
Klein, Florian; Diskin, Ron; et el. (2013) Somatic
Mutations of the Immunoglobulin Framework Are Generally Required for
Broad and Potent HIV-1 Neutralization ; Cell; Vol. 153; No. 1;
126-138; PMCID PMC3792590; 10.1016/j.cell.2013.03.018
Klein, Florian; Halper-Stromberg, Ariel; et el. (2012) HIV
therapy by a combination of broadly neutralizing antibodies in humanized
mice ; Nature; Vol. 492; No. 7427; 118-122; PMCID PMC3809838; 10.1038/nature11604
Mouquet, Hugo; Scharf, Louise; et el. (2012) Complex-type
N-glycan recognition by potent broadly neutralizing HIV antibodies ;
Proceedings of the National Academy of Sciences of the United States of
America; Vol. 109; No. 47; E3268-E3277; PMCID PMC3511153; 10.1073/pnas.1217207109
Pietzsch, John; Gruell, Henning; et el. (2012) A
mouse model for HIV-1 entry ; Proceedings of the National Academy of
Sciences of the United States of America; Vol. 109; No. 39; 15859-15864;
PMCID PMC3465400; 10.1073/pnas.1213409109
West, A. P., Jr.; Diskin, R.; et el. (2012) Structural
basis for germline gene usage of a potent class of antibodies targeting
the CD4 binding site of HIV-1 gp120 ; Retrovirology; Vol. 9; No. S2;
Art. No. O33; PMCID PMC3441645; 10.1186/1742-4690-9-S2-O33
West, Anthony P., Jr.; Diskin, Ron; et el. (2012) Structural
basis for germ-line gene usage of a potent class of antibodies targeting
the CD4-binding site of HIV-1 gp120 ; Proceedings of the National
Academy of Sciences of the United States of America; Vol. 109; No. 30;
E2983-E2090; PMCID PMC3409792; 10.1073/pnas.1208984109
Ladinsky, Mark S.; Huey-Tubman, Kathryn E.; et el. (2012) Electron
tomography of late stages of FcRn-mediated antibody transcytosis in
neonatal rat small intestine ; Molecular Biology of the Cell; Vol.
23; No. 13; 2537-2545; PMCID PMC3386217; 10.1091/mbc.E12-02-0093
Ndjamen, Blaise; Farley, Alexander; et el. (2012) A
Model System to Investigate Antibody Bipolar Bridging Mediated by gE-gI,
a Herpes Virus Fc Receptor ; FASEB Journal; Vol. 26; Art.
No. 605.8
West, Anthony P., Jr.; Galimidi, Rachel P.; et el. (2012) Single-Chain
Fv-Based Anti-HIV Proteins: Potential and Limitations ; Journal of
Virology; Vol. 86; No. 1; 195-202; PMCID PMC3255864; 10.1128/JVI.05848-11
Diskin, Ron; Scheid, Johannes F.; et el. (2011) Increasing
the Potency and Breadth of an HIV Antibody by Using Structure-Based
Rational Design ; Science; Vol. 334; No. 6060; 1289-1293; PMCID
PMC3232316; 10.1126/science.1213782
Bai, Yu; Ye, Lilin; et el. (2011) Intracellular
neutralization of viral infection in polarized epithelial cells by
neonatal Fc receptor (FcRn)-mediated IgG transport ; Proceedings of
the National Academy of Sciences of the United States of America; Vol.
108; No. 45; 18406-18411; PMCID PMC3215070; 10.1073/pnas.1115348108
Scheid, Johannes F.; Mouquet, Hugo; et el. (2011) Sequence
and Structural Convergence of Broad and Potent HIV Antibodies That Mimic
CD4 Binding ; Science; Vol. 333; No. 6049; 1633-1637; PMCID
PMC3351836; 10.1126/science.1207227
Keeffe, Jennifer R.; Gnanapragasam, Priyanthi N. P.; et el. (2011)
Designed
oligomers of cyanovirin-N show enhanced HIV neutralization ;
Proceedings of the National Academy of Sciences of the United States of
America; Vol. 108; No. 34; 14079-14084; PMCID PMC3161612; 10.1073/pnas.1108777108
He, Yongning and Bjorkman, Pamela J. (2011) Structure
of FcRY, an avian immunoglobulin receptor related to mammalian mannose
receptors, and its complex with IgY ; Proceedings of the National
Academy of Sciences of the United States of America; Vol. 108; No. 30;
12431-12436; PMCID PMC3145690; 10.1073/pnas.1106925108
Yang, Fan; West, Anthony P., Jr.; et el. (2011) Crystal
structure of a hemojuvelin-binding fragment of neogenin at 1.8 Å ;
Journal of Structural Biology; Vol. 174; No. 1; 239-244; PMCID
PMC3074981; 10.1016/j.jsb.2010.10.005
Luo, Xin M.; Lei, Margarida Y. Y.; et el. (2010) Dimeric
2G12 as a Potent Protection against HIV-1 ; PLoS Pathogens; Vol. 6;
No. 12; Art. No. e1001225; PMCID PMC3002980; 10.1371/journal.ppat.1001225
Jerdeva, Galina V.; Tesar, Devin B.; et el. (2010) Comparison
of FcRn- and pIgR-Mediated Transport in MDCK Cells by Fluorescence
Confocal Microscopy ; Traffic; Vol. 11; No. 9; 1205-1220; PMCID
PMC2975666; 10.1111/j.1600-0854.2010.01083.x
Klein, Joshua S.; Webster, Alexandre; et el. (2010) A
dimeric form of the HIV-1 antibody 2G12 elicits potent
antibody-dependent cellular cytotoxicity ; AIDS; Vol. 24; No. 11;
1633-1640; PMCID PMC2898891; 10.1097/QAD.0b013e32833ad8c8
Gleick, P. H.; Anderson, D. J.; et el. (2010) Climate
Change and the Integrity of Science ; Science; Vol. 328; No. 5979;
689-690; PMCID PMC5125622; 10.1126/science.328.5979.689
Klein, Joshua S. and Bjorkman, Pamela J. (2010) Few
and Far Between: How HIV May Be Evading Antibody Avidity ; PLoS
Pathogens; Vol. 6; No. 5; Art. No. e1000908; PMCID PMC2877745; 10.1371/journal.ppat.1000908
Diskin, Ron; Marcovecchio, Paola M.; et el. (2010) Structure
of a clade C HIV-1 gp120 bound to CD4 and CD4-induced antibody reveals
anti-CD4 polyreactivity ; Nature Structural & Molecular Biology;
Vol. 17; No. 5; 608-614; PMCID PMC2949298; 10.1038/nsmb.1796
Tesar, Devin B. and Bjorkman, Pamela J. (2010) An
intracellular traffic jam: Fc receptor-mediated transport of
immunoglobulin G ; Current Opinion in Structural Biology; Vol. 20;
No. 2; 226-233; PMCID PMC2865255; 10.1016/j.sbi.2010.01.010
Li, Li; Fang, Celia J.; et el. (2010) Binding
and uptake of H-ferritin are mediated by human transferrin
receptor-1 ; Proceedings of the National Academy of Sciences of the
United States of America; Vol. 107; No. 8; 3505-3510; PMCID PMC2840523;
10.1073/pnas.0913192107
West, Anthony P., Jr.; Galimidi, Rachel P.; et el. (2010) Evaluation
of CD4-CD4i Antibody Architectures Yields Potent, Broadly Cross-Reactive
Anti-Human Immunodeficiency Virus Reagents ; Journal of Virology;
Vol. 84; No. 1; 261-269; PMCID PMC2798438; 10.1128/JVI.01528-09
Yang, Zhiru; West, Anthony P., Jr.; et el. (2009) Crystal
structure of TNFα complexed with a poxvirus MHC-related TNF binding
protein ; Nature Structural & Molecular Biology; Vol. 16; No. 11;
1189-1191; PMCID PMC2819277; 10.1038/nsmb.1683
He, Yongning; Jensen, Grant J.; et el. (2009) Nanogold
as a specific marker for electron cryotomography ; Microscopy and
Microanalysis; Vol. 15; No. 3; 183-188; PMCID PMC2785728; 10.1017/S1431927609090424
Klein, Joshua S.; Gnanapragasam, Priyanthi N. P.; et el. (2009) Examination
of the contributions of size and avidity to the neutralization
mechanisms of the anti-HIV antibodies b12 and 4E10 ; Proceedings of
the National Academy of Sciences of the United States of America; Vol.
106; No. 18; 7385-7390; PMCID PMC2678646; 10.1073/pnas.0811427106
He, Yongning; Jensen, Grant J.; et el. (2009) Cryo-electron
tomography of homophilic adhesion mediated by the neural cell adhesion
molecule L1 ; Structure; Vol. 17; No. 3; 460-471; PMCID PMC2744468;
10.1016/j.str.2009.01.009
Rice, Adrian E.; Mendez, Michael J.; et el. (2009) Investigation
of the biophysical and cell biological properties of ferroportin, a
multipass integral membrane protein iron exporter ; Journal of
Molecular Biology; Vol. 386; No. 3; 717-732; PMCID PMC2677177; 10.1016/j.jmb.2008.12.063
West, Anthony P., Jr.; Galimidi, Rachel P.; et el. (2009) Design and
Expression of a Dimeric Form of the Human Immunodeficiency Virus Type 1
Antibody 2G12 with Increased Neutralization Potency ; Journal of
Virology; Vol. 83; No. 1; 98-104; PMCID PMC2612297; 10.1128/JVI.01564-08
He, Wanzhong; Ladinsky, Mark S.; et el. (2008) FcRn-mediated
antibody transport across epithelial cells revealed by electron
tomography ; Nature; Vol. 455; No. 7212; 542-546; PMCID PMC2773227;
10.1038/nature07255
Arnon, Tal I.; Kaiser, Jens T.; et el. (2008) The Crystal
Structure of CHIR-AB1: A Primordial Avian Classical Fc Receptor ;
Journal of Molecular Biology; Vol. 381; No. 4; 1012-1024; PMCID
PMC2603183; 10.1016/j.jmb.2008.06.082
Yang, Zhiru and Bjorkman, Pamela J. (2008) Structure
of UL18, a peptide-binding viral MHC mimic, bound to a host inhibitory
receptor ; Proceedings of the National Academy of Sciences of the
United States of America; Vol. 105; No. 29; 10095-10100; PMCID
PMC2465803; 10.1073/pnas.0804551105
Zhang, An-Sheng; Yang, Fan; et el. (2008) Neogenin-mediated
hemojuvelin shedding occurs after hemojuvelin traffics to the plamsa
membrane ; Journal of Biological Chemistry; Vol. 283; No. 25;
17494-17502; PMCID PMC2427329; 10.1074/jbc.M710527200
Morphew, M.; He, W.; et el. (2008) Silver
enhancement of Nanogold particles during freeze substitution for
electron microscopy ; Journal of Microscopy; Vol. 230; No. 2;
263-267; PMCID PMC2722379; 10.1111/j.1365-2818.2008.01983.x
Yang, Fan; West, Anthony P.; et el. (2008) Neogenin
Interacts with Hemojuvelin through Its Two Membrane-Proximal Fibronectin
Type III Domains ; Biochemistry; Vol. 47; No. 14; 4237-4245; PMCID
PMC2819367; 10.1021/bi800036h
Sprague, Elizabeth R.; Reinhard, Henrike; et el. (2008) The Human
Cytomegalovirus Fc Receptor gp68 Binds the Fc CH2-CH3 Interface of
Immunoglobulin G ; Journal of Virology; Vol. 82; No. 7; 3490-3499;
PMCID PMC2268481; 10.1128/JVI.01476-07
Tesar, Devin B.; Cheung, Evelyn J.; et el. (2008) The Chicken
Yolk Sac IgY Receptor, a Mammalian Mannose Receptor Family Member,
Transcytoses IgY across Polarized Epithelial Cells ; Molecular
Biology of the Cell; Vol. 19; No. 4; 1587-1593; PMCID PMC2291411; 10.1091/mbc.E07-09-0972
Schmidt, Paul J.; Toran, Paul T.; et el. (2008) The
Transferrin Receptor Modulates Hfe-Dependent Regulation of Hepcidin
Expression ; Cell Metabolism; Vol. 7; No. 3; 205-214; PMCID
PMC2292811; 10.1016/j.cmet.2007.11.016
He, Wanzhong; Kivork, Christine; et el. (2007) A
freeze substitution fixation-based gold enlarging technique for EM
studies of endocytosed nanogold-labeled molecules ; Journal of
Structural Biology; Vol. 160; No. 1; 103-113; PMCID PMC2076746; 10.1016/j.jsb.2007.07.004
Ja, William W.; West, Anthony P., Jr.; et el. (2007) Extension
of Drosophila melanogaster life span with a GPCR peptide inhibitor ;
Nature Chemical Biology; Vol. 3; No. 7; 415-419; PMCID PMC2803097; 10.1038/nchembio.2007.2
Li, Pingwei; Huey-Tubman, Kathryn E.; et el. (2007) The
structure of a polyQ–anti-polyQ complex reveals binding according to a
linear lattice model ; Nature Structural & Molecular Biology;
Vol. 14; No. 5; 381-387; 10.1038/nsmb1234
Tesar, Devin B.; Tiangco, Noreen E.; et el. (2006) Ligand
Valency Affects Transcytosis, Recycling and Intracellular Trafficking
Mediated by the Neonatal Fc Receptor ; Traffic; Vol. 7; No. 9;
1127-1142; PMCID PMC1618808; 10.1111/j.1600-0854.2006.00457.x
Bjorkman, Pamela J. (2006) Finding
the groove ; Nature Immunology; Vol. 7; No. 8; 787-789; 10.1038/ni0806-787
Sprague, Elizabeth R.; Wang, Chu; et el. (2006) Crystal
Structure of the HSV-1 Fc Receptor Bound to Fc Reveals a Mechanism for
Antibody Bipolar Bridging ; PLoS Biology; Vol. 4; No. 6; Art.
No. e148; PMCID PMC1450327; 10.1371/journal.pbio.0040148
Olson, Rich; Dulac, Catherine; et el. (2006) MHC
homologs in the nervous system — they haven’t lost their groove ;
Current Opinion in Neurobiology; Vol. 16; No. 3; 351-357; 10.1016/j.conb.2006.05.007
McDermott, Lindsay C.; Freel, June A.; et el. (2006) Zn-α_2-glycoprotein,
an MHC Class I-Related Glycoprotein Regulator of Adipose Tissues:
Modification or Abrogation of Ligand Binding by Site-Directed
Mutagenesis ; Biochemistry; Vol. 45; No. 7; 2035-2041; 10.1021/bi051881v
Halbrooks, Peter J.; Giannetti, Anthony M.; et el. (2005) Composition
of pH-Sensitive Triad in C-Lobe of Human Serum Transferrin. Comparison
to Sequences of Ovotransferrin and Lactoferrin Provides Insight into
Functional Differences in Iron Release ; Biochemistry; Vol. 44;
No. 47; 15451-15460; 10.1021/bi0518693
Giannetti, Anthony M.; Halbrooks, Peter J.; et el. (2005) The
Molecular Mechanism for Receptor-Stimulated Iron Release from the Plasma
Iron Transport Protein Transferrin ; Structure; Vol. 13; No. 11;
1613-1623; 10.1016/j.str.2005.07.016
Zhang, An-Sheng; West, Anthony P., Jr.; et el. (2005) Interaction
of hemojuvelin with neogenin results in iron accumulation in human
embryonic kidney 293 cells ; Journal of Biological Chemistry; Vol.
280; No. 40; 33885-33894; 10.1074/jbc.M506207200
Olson, Rich; Huey-Tubman, Kathryn E.; et el. (2005) Structure of
a Pheromone Receptor-Associated MHC Molecule with an Open and Empty
Groove ; PLoS Biology; Vol. 3; No. 8; 1436-1448; PMCID PMC1174912; 10.1371/journal.pbio.0030257
Hamburger, Agnes E.; West, Anthony P., Jr.; et el. (2005) Crystal
Structure of a Secreted Insect Ferritin Reveals a Symmetrical
Arrangement of Heavy and Light Chains ; Journal of Molecular Biology;
Vol. 349; No. 3; 558-569; 10.1016/j.jmb.2005.03.074
Davis, Mindy I.; Bennett, Melanie J.; et el. (2005) Crystal
structure of prostate-specific membrane antigen, a tumor marker and
peptidase ; Proceedings of the National Academy of Sciences of the
United States of America; Vol. 102; No. 17; 5981-5986; PMCID PMC556220;
10.1073/pnas.0502101102
Luo, Rensheng; Mann, Beth; et el. (2005) Solution
structure of choline binding protein A, the major adhesin of
Streptococcus pneumoniae ; EMBO Journal; Vol. 24; No. 1; 34-43; PMCID
PMC544903; 10.1038/sj.emboj.7600490
Bjorkman, P. J.; Saper, M. A.; et el. (2005) Pillars
Article: Structure of the human class I histocompatibility antigen,
HLA-A2 ; Journal of Immunology; Vol. 174; No. 1; 6-12
Hamburger, Agnes E.; West, Anthony P., Jr.; et el. (2004) Crystal
Structure of a Polymeric Immunoglobulin Binding Fragment of the Human
Polymeric Immunoglobulin Receptor ; Structure; Vol. 12; No. 11;
1925-1935; 10.1016/j.str.2004.09.006
Delker, Silvia L.; West, Anthony P., Jr.; et el. (2004) Crystallographic
studies of ligand binding by Zn-α_2-glycoprotein ; Journal of
Structural Biology; Vol. 148; No. 2; 205-213; 10.1016/j.jsb.2004.04.009
Giannetti, Anthony M. and Bjorkman, Pamela J. (2004) HFE and
transferrin directly compete for transferrin receptor in solution and at
the cell surface ; Journal of Biological Chemistry; Vol. 279; No. 24;
25866-25875; 10.1074/jbc.M401467200
West, Anthony P., Jr.; Herr, Andrew B.; et el. (2004) The
Chicken Yolk Sac IgY Receptor, a Functional Equivalent of the Mammalian
MHC-Related Fc Receptor, Is a Phospholipase A_2 Receptor Homolog ;
Immunity; Vol. 20; No. 5; 601-610; 10.1016/S1074-7613(04)00113-X
Sprague, Elizabeth R.; Martin, W. Lance; et el. (2004) pH
Dependence and Stoichiometry of Binding to the Fc Region of IgG by the
Herpes Simplex Virus Fc Receptor gE-gI ; Journal of Biological
Chemistry; Vol. 279; No. 14; 14184-14193; 10.1074/jbc.M313281200
Giannetti, Anthony M.; Snow, Peter M.; et el. (2003) Mechanism for
Multiple Ligand Recognition by the Human Transferrin Receptor ; PLoS
Biology; Vol. 1; No. 3; 341-350; PMCID PMC300677; 10.1371/journal.pbio.0000051
Willcox, Benjamin E.; Thomas, Leonard M.; et el. (2003) Crystal
structure of HLA-A2 bound to LIR-1, a host and viral major
histocompatibility complex receptor ; Nature Immunology; Vol. 4;
No. 9; 913-919; 10.1038/ni961
Herr, Andrew B.; Ballister, Edward R.; et el. (2003) Insights
into IgA-mediated immune responses from the crystal structures of human
FcαRI and its complex with IgA1-Fc ; Nature; Vol. 423; No. 6940;
614-620; 10.1038/nature01685
Herr, Andrew B.; White, Clinton L.; et el. (2003) Bivalent
Binding of IgA1 to FcαRI Suggests a Mechanism for Cytokine Activation of
IgA Phagocytosis ; Journal of Molecular Biology; Vol. 327; No. 3;
645-657; 10.1016/S0022-2836(03)00149-9
Vogt, Todd M.; Blackwell, Aaron D.; et el. (2003) Heterotypic
interactions between transferrin receptor and transferrin receptor
2 ; Blood; Vol. 101; No. 5; 2008-2014; 10.1182/blood-2002-09-2742
Willcox, Benjamin E.; Thomas, Leonard M.; et el. (2002) Crystal
structure of LIR-2 (ILT4) at 1.8 Å: differences from LIR-1 (ILT2) in
regions implicated in the binding of the Human Cytomegalovirus class I
MHC homolog UL18 ; BMC Structural Biology; Vol. 2; Art. No. 6; PMCID
PMC130215; 10.1186/1472-6807-2-6
Bennett, Melanie J.; Huey-Tubman, Kathryn E.; et el. (2002) A
linear lattice model for polyglutamine in CAG-expansion diseases ;
Proceedings of the National Academy of Sciences of the United States of
America; Vol. 99; No. 18; 11634-11639; PMCID PMC129321; 10.1073/pnas.182393899
West, Anthony P., Jr.; Giannetti, Anthony M.; et el. (2001) Mutational
analysis of the transferrin receptor reveals overlapping HFE and
transferrin binding sites ; Journal of Molecular Biology; Vol. 313;
No. 2; 385-397; 10.1006/jmbi.2001.5048
Kennedy, Malcolm W.; Heikema, Astrid P.; et el. (2001) Hydrophobic
Ligand Binding by Zn-α_2-glycoprotein, a Soluble Fat-depleting Factor
Related to Major Histocompatibility Complex Proteins ; Journal of
Biological Chemistry; Vol. 276; No. 37; 35008-35013; 10.1074/jbc.C100301200
O’Callaghan, Christopher A.; Cerwenka, Adelheid; et el. (2001) Molecular
Competition for NKG2D: H60 and RAE1 Compete Unequally for NKG2D with
Dominance of H60 ; Immunity; Vol. 15; No. 2; 201-211; 10.1016/S1074-7613(01)00187-X
Martin, W. Lance; West, Anthony P., Jr.; et el. (2001) Crystal
Structure at 2.8 Å of an FcRn/Heterodimeric Fc Complex: Mechanism of
pH-Dependent Binding ; Molecular Cell; Vol. 7; No. 4; 867-877; 10.1016/S1097-2765(01)00230-1
West, Anthony P., Jr.; Llamas, Lynda L.; et el. (2001) Crystal
structure of the ectodomain of Methuselah, a Drosophila G
protein-coupled receptor associated with extended lifespan ;
Proceedings of the National Academy of Sciences of the United States of
America; Vol. 98; No. 7; 3744-3749; PMCID PMC31123; 10.1073/pnas.051625298
Liu, Yang; Misulovin, Ziva; et el. (2001) The
molecular mechanism of sulfated carbohydrate recognition by the
cysteine-rich domain of mannose receptor ; Journal of Molecular
Biology; Vol. 305; No. 3; 481-490; 10.1006/jmbi.2000.4326
West, Anthony P., Jr.; Bennett, Melanie J.; et el. (2000) Comparison
of the Interactions of Transferrin Receptor and Transferrin Receptor 2
with Transferrin and the Hereditary Hemochromatosis Protein HFE ;
Journal of Biological Chemistry; Vol. 275; No. 49; 38135-38138; 10.1074/jbc.C000664200
Chapman, Tara L.; Heikema, Astrid P.; et el. (2000) Crystal
Structure and Ligand Binding Properties of the D1D2 Region of the
Inhibitory Receptor LIR-1 (ILT2) ; Immunity; Vol. 13; No. 5; 727-736;
10.1016/S1074-7613(00)00071-6
West, Anthony P., Jr. and Bjorkman, Pamela J. (2000) Crystal
Structure and Immunoglobulin G Binding Properties of the Human Major
Histocompatibility Complex-Related Fc Receptor ; Biochemistry; Vol.
39; No. 32; 9698-9708; 10.1021/bi000749m
Liu, Yang; Chirino, Arthur J.; et el. (2000) Crystal
Structure of the Cysteine-Rich Domain of Mannose Receptor Complexed with
a Sulfated Carbohydrate Ligand ; Journal of Experimental Medicine;
Vol. 191; No. 7; 1105-1115; PMCID PMC2193177; 10.1084/jem.191.7.1105
Bennett, Melanie J.; Lebrón, José A.; et el. (2000) Crystal
structure of the hereditary haemochromatosis protein HFE complexed with
transferrin receptor ; Nature; Vol. 403; No. 6765; 46-53; 10.1038/47417
Lebrón, José A.; West, Anthony P., Jr.; et el. (1999) The
hemochromatosis protein HFE competes with transferrin for binding to the
transferrin receptor ; Journal of Molecular Biology; Vol. 294; No. 1;
239-245; 10.1006/jmbi.1999.3252
Chapman, Tara L.; Heikema, Astrid P.; et el. (1999) The
Inhibitory Receptor LIR-1 Uses a Common Binding Interaction to Recognize
Class I MHC Molecules and the Viral Homolog UL18 ; Immunity; Vol. 11;
No. 5; 603-613; 10.1016/S1074-7613(00)80135-1
Hamburger, Zsuzsa A.; Brown, Michele S.; et el. (1999) Crystal
Structure of Invasin: A Bacterial Integrin-Binding Protein ; Science;
Vol. 286; No. 5438; 291-295; 10.1126/science.286.5438.291
Martin, W. Lance and Bjorkman, Pamela J. (1999) Characterization
of the 2:1 Complex between the Class I MHC-Related Fc Receptor and Its
Fc Ligand in Solution ; Biochemistry; Vol. 38; No. 39; 12639-12647;
10.1021/bi9913505
Sánchez, Luis M.; Penny, David M.; et el. (1999) Stoichiometry
of the Interaction between the Major Histocompatibility Complex-Related
Fc Receptor and Its Fc Ligand ; Biochemistry; Vol. 38; No. 29;
9471-9476; 10.1021/bi9907330
Hanke, Thomas; Takizawa, Hisao; et el. (1999) Direct
Assessment of MHC Class I Binding by Seven Ly49 Inhibitory NK Cell
Receptors ; Immunity; Vol. 11; No. 1; 67-77; 10.1016/S1074-7613(00)80082-5
Lebrón, José A. and Bjorkman, Pamela J. (1999) The
Transferrin Receptor Binding Site on HFE, the Class I MHC-related
Protein Mutated in Hereditary Hemochromatosis ; Journal of Molecular
Biology; Vol. 289; No. 4; 1109-1118; 10.1006/jmbi.1999.2842
Sánchez, Luis M.; Chirino, Arthur J.; et el. (1999) Crystal
Structure of Human ZAG, a Fat-Depleting Factor Related to MHC
Molecules ; Science; Vol. 283; No. 5409; 1914-1919; 10.1126/science.283.5409.1914
Chapman, Tara L.; You, Il; et el. (1999) Characterization
of the Interaction between the Herpes Simplex Virus Type I Fc Receptor
and Immunoglobulin G ; Journal of Biological Chemistry; Vol. 274;
No. 11; 6911-6999; 10.1074/jbc.274.11.6911
Lebrón, José A.; Shen, Huazhang; et el. (1999) Tolerization
of adult mice to immunodominant proteins before monoclonal antibody
production ; Journal of Immunological Methods; Vol. 222; No. 1-2;
59-63; 10.1016/S0022-1759(98)00179-3
Weng, Zhiping; Gulukota, Kamalakar; et el. (1998) Computational
determination of the structure of rat Fc bound to the neonatal Fc
receptor ; Journal of Molecular Biology; Vol. 282; No. 2; 217-225; 10.1006/jmbi.1998.2020
Su, Xiao-Dong; Gastinel, Louis N.; et el. (1998) Crystal
Structure of Hemolin: A Horseshoe Shape with Implications for Homophilic
Adhesion ; Science; Vol. 281; No. 5379; 991-995; 10.1126/science.281.5379.991
Leong, Clement C.; Chapman, Tara L.; et el. (1998) Modulation
of Natural Killer Cell Cytotoxicity in Human Cytomegalovirus Infection:
The Role of Endogenous Class I Major Histocompatibility Complex and a
Viral Class I Homolog ; Journal of Experimental Medicine; Vol. 187;
No. 10; 1681-1687; PMCID PMC2212284; 10.1084/jem.187.10.1681
Lebrón, José A.; Bennett, Melanie J.; et el. (1998) Crystal
Structure of the Hemochromatosis Protein HFE and Characterization of Its
Interaction with Transferrin Receptor ; Cell; Vol. 93; No. 1;
111-123; 10.1016/S0092-8674(00)81151-4
Feder, John N.; Penny, David M.; et el. (1998) The
hemochromatosis gene product complexes with the transferrin receptor and
lowers its affinity for ligand binding ; Proceedings of the National
Academy of Sciences of the United States of America; Vol. 95; No. 4;
1472-1477; PMCID PMC19050; 10.1073/pnas.95.4.1472
Wilson, Ian A. and Bjorkman, Pamela J. (1998) Unusual
MHC-like molecules; CD1, Fc receptor, the hemochromatosis gene product,
and viral homologs ; Current Opinion in Immunology; Vol. 10; No. 1;
67-73; 10.1016/S0952-7915(98)80034-4
Vaughn, Daniel E. and Bjorkman, Pamela J. (1998) Structural
basis of pH-dependent antibody binding by the neonatal Fc receptor ;
Structure; Vol. 6; No. 1; 63-73; 10.1016/S0969-2126(98)00008-2
Chapman, Tara L. and Bjorkman, Pamela J. (1998) Characterization
of a murine cytomegalovirus class I major histocompati L.bility complex
(MHC) homolog: comparison to MHC molecules and to the human
cytomegalovirus MHC homolog ; Journal of Virology; Vol. 72; No. 1;
460-466; PMCID PMC109395
Vaughn, Daniel E.; Milburn, Christina M.; et el. (1997) Identification
of critical IgG binding epitopes on the neonatal Fc receptor ;
Journal of Molecular Biology; Vol. 274; No. 4; 597-607; 10.1006/jmbi.1997.1388
West, Anthony P., Jr.; Bjorkman, Pamela J.; et el. (1997) Expression
and Circular Dichroism Studies of the Extracellular Domain of the alpha
Subunit of the Nicotinic Acetylcholine Receptor ; Journal of
Biological Chemistry; Vol. 272; No. 41; 25468-25473; 10.1074/jbc.272.41.25468
Vaughn, Daniel E. and Bjorkman, Pamela J. (1997) High-Affinity
Binding of the Neonatal Fc Receptor to Its IgG Ligand Requires Receptor
Immobilization ; Biochemistry; Vol. 36; No. 31; 9374-9380; 10.1021/bi970841r
Morgan, Chantal S.; Holton, James M.; et el. (1997) Circular
dichroism determination of class I MHC-peptide equilibrium dissociation
constants ; Protein Science; Vol. 6; No. 8; 1771-1773; PMCID
PMC2143769; 10.1002/pro.5560060819
Sánchez, Luis M.; López-Otín, Carlos; et el. (1997) Biochemical
characterization and crystalization of human Zn-α2-glycoprotein, a
soluble class I major histocompatibility complex homolog ;
Proceedings of the National Academy of Sciences of the United States of
America; Vol. 94; No. 9; 4626-4630; PMCID PMC20774; 10.1073/pnas.94.9.4626
Bjorkman, Pamela J. (1997) MHC
Restriction in Three Dimensions: A View of T Cell Receptor/Ligand
Interactions ; Cell; Vol. 89; No. 2; 167-170; 10.1016/S0092-8674(00)80195-6
Gakamsky, Dmitry M.; Bjorkman, Pamela J.; et el. (1996) Peptide
Interaction with a Class I Major Histocompatibility Complex-Encoded
Molecule: Allosteric Control of the Ternary Complex Stability ;
Biochemistry; Vol. 35; No. 47; 14841-14848; 10.1021/bi961707u
Raghavan, Malini and Bjorkman, Pamela J. (1996) Fc
receptors and their interactions with immunoglobulins ; Annual Review
of Cell and Developmental Biology; Vol. 12; 181-220; 10.1146/annurev.cellbio.12.1.181
Raghavan, Malini; Lebrón, José A.; et el. (1996) Extended
repertoire of permissible peptide ligands for HLA-B*2702 ; Protein
Science; Vol. 5; No. 10; 2080-2088; PMCID PMC2143273; 10.1002/pro.5560051014
Vaughn, Daniel E. and Bjorkman, Pamela J. (1996) The
(Greek) Key to Structures of Neural Adhesion Molecules ; Neuron; Vol.
16; No. 2; 261-273; 10.1016/S0896-6273(00)80045-8
Raghavan, Malini; Wang, Yongping; et el. (1995) Effects
of receptor dimerization on the interaction between the class I major
histocompatibility complex-related Fc receptor and IgG ; Proceedings
of the National Academy of Sciences of the United States of America;
Vol. 92; No. 24; 11200-11204; PMCID PMC40599; 10.1073/pnas.92.24.11200
Raghavan, Malini; Bonagura, Vincent R.; et el. (1995) Analysis
of the pH Dependence of the Neonatal Fc Receptor/Immunoglobulin G
Interaction Using Antibody and Receptor Variants ; Biochemistry; Vol.
34; No. 45; 14649-14657; 10.1021/bi00045a005
Fahnestock, Margaret L.; Johnson, Jennifer L.; et el. (1995) The
MHC class I homolog encoded by human cytomegalovirus binds endogenous
peptides ; Immunity; Vol. 3; No. 5; 583-590; 10.1016/1074-7613(95)90129-9
Raghavan, Malini and Bjorkman, Pamela J. (1995) BIAcore:
a microchip-based system for analyzing the formation of macromolecular
complexes ; Structure; Vol. 3; No. 4; 331-333; 10.1016/S0969-2126(01)00164-2.
Bjorkman, Pamela J. and Burmeister, Wilhelm P. (1994) Structures
of two classes of MHC molecules elucidated: crucial differences and
similarities ; Current Opinion in Structural Biology; Vol. 4; No. 6;
852-856; 10.1016/0959-440X(94)90266-6
Burmeister, Wilhelm P.; Gastinel, Louis N.; et el. (1994) Crystal
structure at 2.2 Å resolution of the MHC-related neonatal Fc
receptor ; Nature; Vol. 372; No. 6504; 336-343; 10.1038/372336a0
Burmeister, Wilhelm P.; Huber, Andrew H.; et el. (1994) Crystal
structure of the complex of rat neonatal Fc receptor with Fc ;
Nature; Vol. 372; No. 6504; 379-383; 10.1038/372379a0
Strong, Roland K.; Penny, David M.; et el. (1994) Engineering
and expression of a secreted murine TCR with reduced N-linked
glycosylation ; Journal of Immunology; Vol. 153; No. 9;
4111-4121
Strong, Roland K.; Vaughn, Daniel E.; et el. (1994) Expression
and Crystallization of a Soluble Form of Drosophila Fasciclin III ;
Journal of Molecular Biology; Vol. 241; No. 3; 483-487; 10.1006/jmbi.1994.1523
Fahnestock, Margaret L.; Johnson, Jennifer L.; et el. (1994) Effects
of Peptide Length and Composition on Binding to an Empty Class I MHC
Heterodimer ; Biochemistry; Vol. 33; No. 26; 8149-8158; 10.1021/bi00192a020
Raghavan, Malini; Chen, Marcus Y.; et el. (1994) Investigation
of the interaction between the class I MHC-related Fc receptor and its
immunoglobulin G ligand ; Immunity; Vol. 1; No. 4; 303-315; 10.1016/1074-7613(94)90082-5
Huber, Andrew H.; Wang, Yu-mei Eureka; et el. (1994) Crystal
structure of tandem type III fiibronectin domains from drosophila
neuroglian at 2.0 Å ; Neuron; Vol. 12; No. 4; 717-731; 10.1016/0896-6273(94)90326-3
Fahnestock, Margaret L.; Dadgari, Joseph M.; et el. (1994) Phosphatidyl
inositol-linked forms of a murine class I MHC molecule expressed on
Chinese hamster ovary cells retain peptide binding capability and
alloreactivity ; International Immunology; Vol. 6; No. 2; 307-314; 10.1093/intimm/6.2.307
Raghavan, Malini; Gastinel, Louis N.; et el. (1993) The
class I major histocompatibility complex related Fc receptor shows
pH-dependent stability differences correlating with immunoglobulin
binding and release ; Biochemistry; Vol. 32; No. 33; 8654-8660; 10.1021/bi00084a037
Huber, Andrew H.; Kelley, Robert F.; et el. (1993) Crystallization
and Stoichiometry of Binding of a Complex between a Rat Intestinal Fc
Receptor and Fc ; Journal of Molecular Biology; Vol. 230; No. 3;
1077-1083; 10.1006/jmbi.1993.1220
Wang, Wen-Ching; Zinn, Kai; et el. (1993) Expression
and Structural Studies of Fasciclin I, an Insect Cell Adhesion
Molecule ; Journal of Biological Chemistry; Vol. 268; No. 2;
1448-1455
Fahnestock, Margaret L.; Tamir, Ilana; et el. (1992) Thermal
stability comparison of purified empty and peptide-filled forms of a
class I MHC molecule ; Science; Vol. 258; No. 5088; 1658-1662; 10.1126/science.1360705
Gastinel, Louis N.; Simister, Neil E.; et el. (1992) Expression
and crystallization of a soluble and functional form of an Fc receptor
related to class I histocompatibility molecules ; Proceedings of the
National Academy of Sciences of the United States of America; Vol. 89;
No. 2; 638-642; PMCID PMC48294; 10.1073/pnas.89.2.638
Devaux, Brigitte; Bjorkman, Pamela J.; et el. (1991) Generation
of monoclonal antibodies against soluble human T cell receptor
polypeptides ; European Journal of Immunology; Vol. 21; No. 9;
2111-2119; 10.1002/eji.1830210920
Saper, M. A.; Bjorkman, P. J.; et el. (1991) Refined
structure of the human histocompatibility antigen HLA-A2 at 2.6 Å
resolution ; Journal of Molecular Biology; Vol. 219; No. 2; 277-319;
10.1016/0022-2836(91)90567-P
Chamow, Steven M.; Peers, David H.; et el. (1990) Enzymatic
Cleavage of a CD4 Immunoadhesin Generates Crystallizable, Biologically
Active Fd-like Fragments ; Biochemistry; Vol. 29; No. 42; 9885-9891;
10.1021/bi00494a019
Bjorkman, Pamela J. and Parham, Peter (1990) Structure,
Function, and Diversity of Class I Major Histocompatibility Complex
Molecules ; Annual Review of Biochemistry; Vol. 59; 253-288; 10.1146/annurev.bi.59.070190.001345
Garrett, T. P. J.; Saper, M. A.; et el. (1989) Specificity
pockets for the side chains of peptide antigens in HLA-Aw68 ; Nature;
Vol. 342; No. 6250; 692-696; 10.1038/342692a0
Davis, M. M.; Chien, Yueh-Hsiu; et el. (1989) A
Possible Basis for Major Histocompatibility Complex-Restricted T-Cell
Recognition ; Philosophical Transactions of the Royal Society of
London. Series B, Biological Sciences; Vol. 323; No. 1217; 521-524; 10.1098/rstb.1989.0030
Bjorkman, P. J. and Davis, M. M. (1989) Model
for the Interaction of T-cell Receptors with Peptide/MHC Complexes ;
Cold Spring Harbor Symposia on Quantitative Biology; Vol. 54; 365-373;
10.1101/SQB.1989.054.01.045
Davis, M. M.; Berg, L. J.; et el. (1989) TCR
Recognition and Selection In Vivo ; Cold Spring Harbor Symposia on
Quantitative Biology; Vol. 54; No. 0; 119-128; 10.1101/SQB.1989.054.01.015