Shen, Cheng; Lamba, Adiyant et al. (2022) Stain-free detection of embryo polarization using deep learning Scientific Reports; Vol. 12;

https://resolver.caltech.edu/CaltechAUTHORS:20220215-496417800

Duethorn, Binyamin; Groll, Fabian et al. (2022) Lima1 mediates the pluripotency control of membrane dynamics and cellular metabolism Nature Communications; Vol. 13;

https://resolver.caltech.edu/CaltechAUTHORS:20220201-160162400

Liang, Xuan; Weberling, Antonia et al. (2021) E-cadherin mediated Apical Membrane Initiation Site localisation

https://resolver.caltech.edu/CaltechAUTHORS:20211214-786549900

Rawlings, Thomas M.; Makwana, Komal et al. (2021) Modelling the impact of decidual senescence on embryo implantation in human endometrial assembloids eLife; Vol. 10;

https://resolver.caltech.edu/CaltechAUTHORS:20211124-161127351

Zhu, Meng; Shahbazi, Marta et al. (2021) Human embryo polarization requires PLC signaling to mediate trophectoderm specification eLife; Vol. 10;

https://resolver.caltech.edu/CaltechAUTHORS:20200925-104734056

Sozen, Berna; Jorgensen, Victoria et al. (2021) Reconstructing aspects of human embryogenesis with pluripotent stem cells Nature Communications; Vol. 12;

https://resolver.caltech.edu/CaltechAUTHORS:20210317-080317393

Mackinlay, Kirsty M. L.; Weatherbee, Bailey A. T. et al. (2021) An in vitro stem cell model of human epiblast and yolk sac interaction eLife; Vol. 10;

https://resolver.caltech.edu/CaltechAUTHORS:20210930-211337700

Molè, Matteo A.; Coorens, Tim H. H. et al. (2021) A single cell characterisation of human embryogenesis identifies pluripotency transitions and putative anterior hypoblast centre Nature Communications; Vol. 12;

https://resolver.caltech.edu/CaltechAUTHORS:20210618-210040654

Weatherbee, Bailey A. T.; Cui, Tongtong et al. (2021) Modeling human embryo development with embryonic and extra-embryonic stem cells Developmental Biology; Vol. 474;

https://resolver.caltech.edu/CaltechAUTHORS:20201217-133744400

Sozen, Berna; Cornwall-Scoones, Jake et al. (2021) The dynamics of morphogenesis in stem cell-based embryology: Novel insights for symmetry breaking Developmental Biology; Vol. 474;

https://resolver.caltech.edu/CaltechAUTHORS:20201217-133744809

Cornwall-Scoones, Jake; Zernicka-Goetz, Magdalena (2021) Unifying synthetic embryology Developmental Biology; Vol. 474;

https://resolver.caltech.edu/CaltechAUTHORS:20210322-130659658

Orietti, Lorenzo C.; Rosa, Viviane Souza et al. (2021) Embryo Size Regulates the Timing and Mechanism of Pluripotent Tissue Morphogenesis Stem Cell Reports; Vol. 16; No. 5;

https://resolver.caltech.edu/CaltechAUTHORS:20201009-083350141

Guo, Jianying; Wang, Peizhe et al. (2021) Machine learning-assisted high-content analysis of pluripotent stem cell-derived embryos in vitro Stem Cell Reports; Vol. 16; No. 5;

https://resolver.caltech.edu/CaltechAUTHORS:20210504-094816688

Shi, Junchao; Zhang, Yunfang et al. (2021) PANDORA-seq expands the repertoire of regulatory small RNAs by overcoming RNA modifications Nature Cell Biology; Vol. 23; No. 4;

https://resolver.caltech.edu/CaltechAUTHORS:20210211-165540246

Molè, Matteo Amitaba; Weberling, Antonia et al. (2021) Integrin β1 coordinates survival and morphogenesis of the embryonic lineage upon implantation and pluripotency transition Cell Reports; Vol. 34; No. 10;

https://resolver.caltech.edu/CaltechAUTHORS:20210310-141520229

Amadei, Gianluca; Lau, Kasey Y. C. et al. (2021) Inducible Stem-Cell-Derived Embryos Capture Mouse Morphogenetic Events In Vitro Developmental Cell; Vol. 56; No. 3;

https://resolver.caltech.edu/CaltechAUTHORS:20210104-164232285

Sozen, Berna; Demir, Necdet et al. (2021) BMP signalling is required for extra-embryonic ectoderm development during pre-to-post-implantation transition of the mouse embryo Developmental Biology; Vol. 470;

https://resolver.caltech.edu/CaltechAUTHORS:20201117-110225184

Weberling, Antonia; Zernicka-Goetz, Magdalena (2021) Trophectoderm mechanics direct epiblast shape upon embryo implantation Cell Reports; Vol. 34; No. 3;

https://resolver.caltech.edu/CaltechAUTHORS:20210119-143307098

Zhu, Meng; Cornwall-Scoones, Jake et al. (2020) Developmental clock and mechanism of de novo polarization of the mouse embryo Science; Vol. 370; No. 6522;

https://resolver.caltech.edu/CaltechAUTHORS:20200212-084819179

Zhu, Meng; Zernicka-Goetz, Magdalena (2020) Principles of Self-Organization of the Mammalian Embryo Cell; Vol. 183; No. 6;

https://resolver.caltech.edu/CaltechAUTHORS:20201210-160239379

Lynch, Cian J.; Bernad, Raquel et al. (2020) Global hyperactivation of enhancers stabilizes human and mouse naive pluripotency through inhibition of CDK8/19 Mediator kinases Nature Cell Biology; Vol. 22; No. 10;

https://resolver.caltech.edu/CaltechAUTHORS:20201012-163632801

Cornwall-Scoones, Jake; Zernicka-Goetz, Magdalena (2020) Starting life in space National Science Review; Vol. 7; No. 9;

https://resolver.caltech.edu/CaltechAUTHORS:20201009-152128912

Shahbazi, Marta N.; Wang, Tianren et al. (2020) Developmental potential of aneuploid human embryos cultured beyond implantation Nature Communications; Vol. 11;

https://resolver.caltech.edu/CaltechAUTHORS:20200811-114715166

Weatherbee, Bailey A. T.; Glover, David M. et al. (2020) Expression of SARS-CoV-2 receptor ACE2 and the protease TMPRSS2 suggests susceptibility of the human embryo in the first trimester Open Biology; Vol. 10; No. 8;

https://resolver.caltech.edu/CaltechAUTHORS:20200805-090719433

Singla, Shruti; Iwamoto-Stohl, Lisa K. et al. (2020) Autophagy-mediated apoptosis eliminates aneuploid cells in a mouse model of chromosome mosaicism Nature Communications; Vol. 11;

https://resolver.caltech.edu/CaltechAUTHORS:20200611-161658303

Kyprianou, Christos; Christodoulou, Neophytos et al. (2020) Basement membrane remodelling regulates mouse embryogenesis Nature; Vol. 582; No. 7811;

https://resolver.caltech.edu/CaltechAUTHORS:20200121-134023730

Zhu, Meng; Zernicka-Goetz, Magdalena (2020) Living a Sweet Life: Glucose Instructs Cell Fate in the Mouse Embryo Developmental Cell; Vol. 53; No. 1;

https://resolver.caltech.edu/CaltechAUTHORS:20200406-124658130

Zhu, Meng; Zernicka-Goetz, Magdalena (2020) Building an apical domain in the early mouse embryo: Lessons, challenges and perspectives Current Opinion in Cell Biology; Vol. 62;

https://resolver.caltech.edu/CaltechAUTHORS:20200409-115737960

Molè, Matteo A.; Weberling, Antonia et al. (2020) Comparative analysis of human and mouse development: From zygote to pre-gastrulation Gastrulation: From Embryonic Pattern to Form; Current Topics in Developmental Biology; Series.Current Topics in Developmental Biology; No. 136;

https://resolver.caltech.edu/CaltechAUTHORS:20200409-115737860

Sozen, Berna; Cox, Andy L. et al. (2019) Self-Organization of Mouse Stem Cells into an Extended Potential Blastoid Developmental Cell; Vol. 51; No. 6;

https://resolver.caltech.edu/CaltechAUTHORS:20191216-145145496

Aloia, Luigi; McKie, Mikel Alexander et al. (2019) Epigenetic remodelling licences adult cholangiocytes for organoid formation and liver regeneration Nature Cell Biology; Vol. 21; No. 11;

https://resolver.caltech.edu/CaltechAUTHORS:20191111-124015897

Anikeeva, Polina; Cissé, Ibrahim I. et al. (2019) Voices in methods development Nature Methods; Vol. 16; No. 10;

https://resolver.caltech.edu/CaltechAUTHORS:20191017-144439188

Christodoulou, Neophytos; Weberling, Antonia et al. (2019) Morphogenesis of extra-embryonic tissues directs the remodelling of the mouse embryo at implantation Nature Communications; Vol. 10;

https://resolver.caltech.edu/CaltechAUTHORS:20200409-115738046

Antonica, Francesco; Orietti, Lorenzo Carlo et al. (2019) Concerted cell divisions in embryonic visceral endoderm guide anterior visceral endoderm migration Developmental Biology; Vol. 450; No. 2;

https://resolver.caltech.edu/CaltechAUTHORS:20190408-111045626

Shahbazi, Marta N.; Siggia, Eric D. et al. (2019) Self-organization of stem cells into embryos: A window on early mammalian development Science; Vol. 364; No. 6444;

https://resolver.caltech.edu/CaltechAUTHORS:20200409-115738157

Hupalowska, Anna; Jedrusik, Agnieszka et al. (2018) CARM1 and Paraspeckles Regulate Pre-implantation Mouse Embryo Development Cell; Vol. 175; No. 7;

https://resolver.caltech.edu/CaltechAUTHORS:20190408-111045813

Rivron, Nicolas; Pera, Martin et al. (2018) Debate ethics of embryo models from stem cells Nature; Vol. 564; No. 7735;

https://resolver.caltech.edu/CaltechAUTHORS:20190408-111045932

Christodoulou, Neophytos; Kyprianou, Christos et al. (2018) Sequential formation and resolution of multiple rosettes drive embryo remodelling after implantation Nature Cell Biology; Vol. 20; No. 11;

https://resolver.caltech.edu/CaltechAUTHORS:20190408-111046061

McCann, Beverly J.; Cox, Andy et al. (2018) Delivery of mtZFNs into Early Mouse Embryos Zinc Finger Proteins: Methods and Protocols; Methods in Molecular Biology; Series.Methods in Molecular Biology; No. 1867;

https://resolver.caltech.edu/CaltechAUTHORS:20190408-161504340

Shahbazi, Marta N.; Zernicka-Goetz, Magdalena (2018) Deconstructing and reconstructing the mouse and human early embryo Nature Cell Biology; Vol. 20; No. 8;

https://resolver.caltech.edu/CaltechAUTHORS:20190405-170314164

Sozen, Berna; Amadei, Gianluca et al. (2018) Self-assembly of embryonic and two extra-embryonic stem cell types into gastrulating embryo-like structures Nature Cell Biology; Vol. 20; No. 8;

https://resolver.caltech.edu/CaltechAUTHORS:20190408-111046182

Harrison, Sarah Ellys; Sozen, Berna et al. (2018) In vitro generation of mouse polarized embryo-like structures from embryonic and trophoblast stem cells Nature Protocols; Vol. 13; No. 7;

https://resolver.caltech.edu/CaltechAUTHORS:20190405-170314258

Chen, Qi; Shi, Junchao et al. (2018) Tracing the origin of heterogeneity and symmetry breaking in the early mammalian embryo Nature Communications; Vol. 9;

https://resolver.caltech.edu/CaltechAUTHORS:20190408-111046445

Papaspyropoulos, Angelos; Bradley, Leanne et al. (2018) RASSF1A uncouples Wnt from Hippo signalling and promotes YAP mediated differentiation via p73 Nature Communications; Vol. 9;

https://resolver.caltech.edu/CaltechAUTHORS:20190408-111046546

Strauss, Bernhard; Harrison, Andrew et al. (2018) Cyclin B1 is essential for mitosis in mouse embryos, and its nuclear export sets the time for mitosis Journal of Cell Biology; Vol. 217; No. 1;

https://resolver.caltech.edu/CaltechAUTHORS:20190408-111046720

Shahbazi, Marta N.; Scialdone, Antonio et al. (2017) Pluripotent state transitions coordinate morphogenesis in mouse and human embryos Nature; Vol. 552; No. 7684;

https://resolver.caltech.edu/CaltechAUTHORS:20190408-111046314

Bury, Leah; Coelho, Paula A. et al. (2017) Plk4 and Aurora A cooperate in the initiation of acentriolar spindle assembly in mammalian oocytes Journal of Cell Biology; Vol. 216; No. 11;

https://resolver.caltech.edu/CaltechAUTHORS:20190408-162605585

Hurlbut, J. Benjamin; Hyun, Insoo et al. (2017) Revisiting the Warnock rule Nature Biotechnology; Vol. 35; No. 11;

https://resolver.caltech.edu/CaltechAUTHORS:20190408-161923858

Zhu, Meng; Leung, Chuen Yan et al. (2017) Actomyosin polarisation through PLC-PKC triggers symmetry breaking of the mouse embryo Nature Communications; Vol. 8;

https://resolver.caltech.edu/CaltechAUTHORS:20190405-170314469

Ajduk, Anna; Strauss, Bernhard et al. (2017) Delayed APC/C activation extends the first mitosis of mouse embryos Scientific Reports; Vol. 7;

https://resolver.caltech.edu/CaltechAUTHORS:20190405-170314558

Goolam, Mubeen; Zernicka-Goetz, Magdalena (2017) The chromatin modifier Satb1 regulates cell fate through Fgf signalling in the early mouse embryo Development; Vol. 144; No. 8;

https://resolver.caltech.edu/CaltechAUTHORS:20190405-170314644

Harrison, Sarah Ellys; Sozen, Berna et al. (2017) Assembly of embryonic and extraembryonic stem cells to mimic embryogenesis in vitro Science; Vol. 356; No. 6334;

https://resolver.caltech.edu/CaltechAUTHORS:20190405-170314754

Zernicka-Goetz, Magdalena (2016) Andrzej K. Tarkowski 1933–2016 Nature Cell Biology; Vol. 18; No. 12;

https://resolver.caltech.edu/CaltechAUTHORS:20190409-122829890

Ajduk, Anna; Zernicka-Goetz, Magdalena (2016) Polarity and cell division orientation in the cleavage embryo: from worm to human Molecular Human Reproduction; Vol. 22; No. 10;

https://resolver.caltech.edu/CaltechAUTHORS:20190409-123144282

Leung, C. Y.; Zhu, M. et al. (2016) Polarity in Cell-Fate Acquisition in the Early Mouse Embryo Mammalian Preimplantation Development; Current Topics in Developmental Biology; Series.Current Topics in Developmental Biology; No. 120;

https://resolver.caltech.edu/CaltechAUTHORS:20190409-140137785

Shahbazi, Marta N.; Jedrusik, Agnieszka et al. (2016) Self-organization of the human embryo in the absence of maternal tissues Nature Cell Biology; Vol. 18; No. 6;

https://resolver.caltech.edu/CaltechAUTHORS:20190405-170314855

Deglincerti, Alessia; Croft, Gist F. et al. (2016) Self-organization of the in vitro attached human embryo Nature; Vol. 533; No. 7602;

https://resolver.caltech.edu/CaltechAUTHORS:20190405-170314964

Panamarova, Maryna; Cox, Andy et al. (2016) The BAF chromatin remodelling complex is an epigenetic regulator of lineage specification in the early mouse embryo Development; Vol. 143; No. 8;

https://resolver.caltech.edu/CaltechAUTHORS:20190405-170315353

Bolton, Helen; Graham, Sarah J. L. et al. (2016) Mouse model of chromosome mosaicism reveals lineage-specific depletion of aneuploid cells and normal developmental potential Nature Communications; Vol. 7;

https://resolver.caltech.edu/CaltechAUTHORS:20190405-170315061

Goolam, Mubeen; Scialdone, Antonio et al. (2016) Heterogeneity in Oct4 and Sox2 Targets Biases Cell Fate in 4-Cell Mouse Embryos Cell; Vol. 165; No. 1;

https://resolver.caltech.edu/CaltechAUTHORS:20190405-170315162

Graham, Sarah J. L.; Zernicka-Goetz, Magdalena (2016) The Acquisition of Cell Fate in Mouse Development: How Do Cells First Become Heterogeneous? Essays on Developmental Biology, Part B; Current Topics in Developmental Biology; Series.Current Topics in Developmental Biology; No. 117;

https://resolver.caltech.edu/CaltechAUTHORS:20190405-170315260

Bedzhov, Ivan; Bialecka, Monika et al. (2015) Development of the anterior-posterior axis is a self-organizing process in the absence of maternal cues in the mouse embryo Cell Research; Vol. 25; No. 12;

https://resolver.caltech.edu/CaltechAUTHORS:20190405-170315710

Coelho, Paula A.; Bury, Leah et al. (2015) Over-expression of Plk4 induces centrosome amplification, loss of primary cilia and associated tissue hyperplasia in the mouse Open Biology; Vol. 5; No. 12;

https://resolver.caltech.edu/CaltechAUTHORS:20190405-170315456

Leung, Chuen Yan; Zernicka-Goetz, Magdalena (2015) Mapping the journey from totipotency to lineage specification in the mouse embryo Current Opinion in Genetics and Development; Vol. 34;

https://resolver.caltech.edu/CaltechAUTHORS:20190405-170315620

Macaulay, Iain C.; Haerty, Wilfried et al. (2015) G&T-seq: parallel sequencing of single-cell genomes and transcriptomes Nature Methods; Vol. 12; No. 6;

https://resolver.caltech.edu/CaltechAUTHORS:20190405-170315821

Bedzhov, Ivan; Zernicka-Goetz, Magdalena (2015) Cell death and morphogenesis during early mouse development: Are they interconnected? Bioessays; Vol. 37; No. 4;

https://resolver.caltech.edu/CaltechAUTHORS:20190405-170315955

Jedrusik, Agnieszka; Cox, Andy et al. (2015) Maternal-zygotic knockout reveals a critical role of Cdx2 in the morula to blastocyst transition Developmental Biology; Vol. 398; No. 2;

https://resolver.caltech.edu/CaltechAUTHORS:20190405-170316054

Graham, Sarah J. L.; Wicher, Krzysztof B. et al. (2014) BMP signalling regulates the pre-implantation development of extra-embryonic cell lineages in the mouse embryo Nature Communications; Vol. 5;

https://resolver.caltech.edu/CaltechAUTHORS:20190405-170316127

Bedzhov, Ivan; Graham, Sarah J. L. et al. (2014) Developmental plasticity, cell fate specification and morphogenesis in the early mouse embryo Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences; Vol. 369; No. 1657;

https://resolver.caltech.edu/CaltechAUTHORS:20190409-154015645

Zernicka-Goetz, Magdalena; Hadjantonakis, Anna-Katerina (2014) From pluripotency to differentiation: laying foundations for the body pattern in the mouse embryo Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences; Vol. 369; No. 1657;

https://resolver.caltech.edu/CaltechAUTHORS:20190409-162629840

Bedzhov, Ivan; Leung, Chuen Yan et al. (2014) In vitro culture of mouse blastocysts beyond the implantation stages Nature Protocols; Vol. 9; No. 12;

https://resolver.caltech.edu/CaltechAUTHORS:20190405-170316220

Ajduk, Anna; Biswas Shivhare, Sourima et al. (2014) The basal position of nuclei is one pre-requisite for asymmetric cell divisions in the early mouse embryo Developmental Biology; Vol. 392; No. 2;

https://resolver.caltech.edu/CaltechAUTHORS:20190405-170316275

Rosenthal, Nadia; Zernicka-Goetz, Magdalena (2014) A tribute to Sir John Gurdon Differentiation; Vol. 88; No. 1;

https://resolver.caltech.edu/CaltechAUTHORS:20190409-163953574

Christophorou, Maria A.; Castelo-Branco, Gonçalo et al. (2014) Citrullination regulates pluripotency and histone H1 binding to chromatin Nature; Vol. 507; No. 7490;

https://resolver.caltech.edu/CaltechAUTHORS:20190405-170316424

Bedzhov, Ivan; Zernicka-Goetz, Magdalena (2014) Self-Organizing Properties of Mouse Pluripotent Cells Initiate Morphogenesis upon Implantation Cell; Vol. 156; No. 5;

https://resolver.caltech.edu/CaltechAUTHORS:20190405-170316365

Coelho, Paula A.; Bury, Leah et al. (2013) Spindle Formation in the Mouse Embryo Requires Plk4 in the Absence of Centrioles Developmental Cell; Vol. 27; No. 5;

https://resolver.caltech.edu/CaltechAUTHORS:20190405-170316524

Morris, Samantha A.; Graham, Sarah J. L. et al. (2013) The differential response to Fgf signalling in cells internalized at different times influences lineage segregation in preimplantation mouse embryos Open Biology; Vol. 3; No. 11;

https://resolver.caltech.edu/CaltechAUTHORS:20190405-170316664

Duan, En-kui; Wang, Haibin et al. (2013) Introduction to the special issue “Molecular Players in Early Pregnancy” Molecular Aspects of Medicine; Vol. 34; No. 5;

https://resolver.caltech.edu/CaltechAUTHORS:20190405-170316577

Ajduk, Anna; Zernicka-Goetz, Magdalena (2013) Quality control of embryo development Molecular Aspects of Medicine; Vol. 34; No. 5;

https://resolver.caltech.edu/CaltechAUTHORS:20190411-124904165

Leung, Chuen Yan; Zernicka-Goetz, Magdalena (2013) Angiomotin prevents pluripotent lineage differentiation in mouse embryos via Hippo pathway-dependent and -independent mechanisms Nature Communications; Vol. 4;

https://resolver.caltech.edu/CaltechAUTHORS:20190405-170316805

Skamagki, Maria; Wicher, Krzysztof B. et al. (2013) Asymmetric Localization of Cdx2 mRNA during the First Cell-Fate Decision in Early Mouse Development Cell Reports; Vol. 3; No. 2;

https://resolver.caltech.edu/CaltechAUTHORS:20190405-170316855

Zernicka-Goetz, Magdalena (2013) Development: Do Mouse Embryos Play Dice? Current Biology; Vol. 23; No. 1;

https://resolver.caltech.edu/CaltechAUTHORS:20190411-125134537

Pasque, Vincent; Radzisheuskaya, Aliaksandra et al. (2012) Histone variant macroH2A marks embryonic differentiation in vivo and acts as an epigenetic barrier to induced pluripotency Journal of Cell Science; Vol. 125; No. 24;

https://resolver.caltech.edu/CaltechAUTHORS:20190417-152709124

Morris, Samantha A.; Guo, Yu et al. (2012) Developmental Plasticity Is Bound by Pluripotency and the Fgf and Wnt Signaling Pathways Cell Reports; Vol. 2; No. 4;

https://resolver.caltech.edu/CaltechAUTHORS:20190417-152709752

Lee, Yun Hwa; Ma, Hui et al. (2012) Protein Arginine Methyltransferase 6 Regulates Embryonic Stem Cell Identity Stem Cells and Development; Vol. 21; No. 14;

https://resolver.caltech.edu/CaltechAUTHORS:20190417-152709819

Morris, Samantha A.; Zernicka-Goetz, Magdalena (2012) Formation of Distinct Cell Types in the Mouse Blastocyst Mouse Development: From Oocyte to Stem Cells; Series.Results and Problems in Cell Differentiation; No. 55;

https://resolver.caltech.edu/CaltechAUTHORS:20190417-152710198

Ajduk, Anna; Zernicka-Goetz, Magdalena (2012) Advances in embryo selection methods F1000 Biology Reports; Vol. 4;

https://resolver.caltech.edu/CaltechAUTHORS:20190417-152710123

Swann, Karl; Windsor, Shane et al. (2012) Phospholipase C-ζ-induced Ca^(2+) oscillations cause coincident cytoplasmic movements in human oocytes that failed to fertilize after intracytoplasmic sperm injection Fertility and Sterility; Vol. 97; No. 3;

https://resolver.caltech.edu/CaltechAUTHORS:20190417-152709920

Morris, Samantha A.; Grewal, Seema et al. (2012) Dynamics of anterior–posterior axis formation in the developing mouse embryo Nature Communications; Vol. 3;

https://resolver.caltech.edu/CaltechAUTHORS:20190417-152710020

Ajduk, Anna; Ilozue, Tagbo et al. (2011) Rhythmic actomyosin-driven contractions induced by sperm entry predict mammalian embryo viability Nature Communications; Vol. 2;

https://resolver.caltech.edu/CaltechAUTHORS:20190417-163114215

Zernicka-Goetz, Magdalena (2011) Proclaiming fate in the early mouse embryo Nature Cell Biology; Vol. 13; No. 2;

https://resolver.caltech.edu/CaltechAUTHORS:20190417-163114357

Sharif, Bedra; Na, Jie et al. (2010) The chromosome passenger complex is required for fidelity of chromosome transmission and cytokinesis in meiosis of mouse oocytes Journal of Cell Science; Vol. 123; No. 24;

https://resolver.caltech.edu/CaltechAUTHORS:20190417-163114460

Zernicka-Goetz, Magdalena; Huang, Sui (2010) Stochasticity versus determinism in development: a false dichotomy? Nature Reviews. Genetics; Vol. 11; No. 11;

https://resolver.caltech.edu/CaltechAUTHORS:20190417-163114563

Bruce, Alexander W.; Zernicka-Goetz, Magdalena (2010) Developmental control of the early mammalian embryo: competition among heterogeneous cells that biases cell fate Current Opinion in Genetics and Development; Vol. 20; No. 5;

https://resolver.caltech.edu/CaltechAUTHORS:20190417-163114658

Parfitt, David-Emlyn; Zernicka-Goetz, Magdalena (2010) Epigenetic Modification Affecting Expression of Cell Polarity and Cell Fate Genes to Regulate Lineage Specification in the Early Mouse Embryo Molecular Biology of the Cell; Vol. 21; No. 15;

https://resolver.caltech.edu/CaltechAUTHORS:20190417-163114865

Jedrusik, Agnieszka; Bruce, Alexander W. et al. (2010) Maternally and zygotically provided Cdx2 have novel and critical roles for early development of the mouse embryo Developmental Biology; Vol. 344; No. 1;

https://resolver.caltech.edu/CaltechAUTHORS:20190417-163114755

Morris, Samantha A.; Teo, Roy T. Y. et al. (2010) Origin and formation of the first two distinct cell types of the inner cell mass in the mouse embryo Proceedings of the National Academy of Sciences of the United States of America; Vol. 107; No. 14;

https://resolver.caltech.edu/CaltechAUTHORS:20190417-163114958

Wu, Qiang; Bruce, Alexander W. et al. (2009) CARM1 Is Required in Embryonic Stem Cells to Maintain Pluripotency and Resist Differentiation Stem Cells; Vol. 27; No. 11;

https://resolver.caltech.edu/CaltechAUTHORS:20190417-163115057

Meilhac, Sigolène M.; Adams, Richard J. et al. (2009) Active cell movements coupled to positional induction are involved in lineage segregation in the mouse blastocyst Developmental Biology; Vol. 331; No. 2;

https://resolver.caltech.edu/CaltechAUTHORS:20190417-163115154

Zernicka-Goetz, Magdalena; Morris, Samantha A. et al. (2009) Making a firm decision: multifaceted regulation of cell fate in the early mouse embryo Nature Reviews. Genetics; Vol. 10; No. 7;

https://resolver.caltech.edu/CaltechAUTHORS:20190418-150055208

Jedrusik, Agnieszka; Parfitt, David-Emlyn et al. (2008) Role of Cdx2 and cell polarity in cell allocation and specification of trophectoderm and inner cell mass in the mouse embryo Genes and Development; Vol. 22; No. 19;

https://resolver.caltech.edu/CaltechAUTHORS:20190418-150055370

Lykke-Andersen, Karin; Gilchrist, Michael J. et al. (2008) Maternal Argonaute 2 Is Essential for Early Mouse Development at the Maternal-Zygotic Transition Molecular Biology of the Cell; Vol. 19; No. 10;

https://resolver.caltech.edu/CaltechAUTHORS:20190418-150055486

Soares, Miguel L.; Torres-Padilla, Maria-Elena et al. (2008) Bone morphogenetic protein 4 signaling regulates development of the anterior visceral endoderm in the mouse embryo Development, Growth & Differentiation; Vol. 50; No. 7;

https://resolver.caltech.edu/CaltechAUTHORS:20190418-150055586

Adjaye, James A.; Byskov, Anne G. et al. (2008) Pluripotency and differentiation in embryos and stem cells - Pavia, 17-18 January 2008 International Journal of Developmental Biology; Vol. 52; No. 7; Pluripotency and differentiation in embryos and stem cells, 17-18 January 2008 , Pavia, Italy

https://resolver.caltech.edu/CaltechAUTHORS:20190418-150055789

Bischoff, Marcus; Parfitt, David-Emlyn et al. (2008) Formation of the embryonic-abembryonic axis of the mouse blastocyst: relationships between orientation of early cleavage divisions and pattern of symmetric/asymmetric divisions Development; Vol. 135; No. 5;

https://resolver.caltech.edu/CaltechAUTHORS:20190418-150055693

Torres-Padilla, Maria-Elena; Richardson, Lucy et al. (2007) The anterior visceral endoderm of the mouse embryo is established from both preimplantation precursor cells and by de novo gene expression after implantation Developmental Biology; Vol. 309; No. 1;

https://resolver.caltech.edu/CaltechAUTHORS:20190418-150055920

Perea-Gomez, Aitana; Meilhac, Sigolène M. et al. (2007) Regionalisation of the mouse visceral endoderm as the blastocyst transforms into the egg cylinder BMC Developmental Biology; Vol. 7;

https://resolver.caltech.edu/CaltechAUTHORS:20190418-150056071

Frankenberg, Stephen; Smith, Lee et al. (2007) Novel gene expression patterns along the proximo-distal axis of the mouse embryo before gastrulation BMC Developmental Biology; Vol. 7;

https://resolver.caltech.edu/CaltechAUTHORS:20190418-150056179

Na, Jie; Lykke-Andersen, Karin et al. (2007) Dishevelled proteins regulate cell adhesion in mouse blastocyst and serve to monitor changes in Wnt signaling Developmental Biology; Vol. 302; No. 1;

https://resolver.caltech.edu/CaltechAUTHORS:20190418-150056272

Torres-Padilla, Maria-Elena; Parfitt, David-Emlyn et al. (2007) Histone arginine methylation regulates pluripotency in the early mouse embryo Nature; Vol. 445; No. 7124;

https://resolver.caltech.edu/CaltechAUTHORS:20190419-105736503

Zernicka-Goetz, Magdalena (2006) The first cell-fate decisions in the mouse embryo: destiny is a matter of both chance and choice Current Opinion in Genetics and Development; Vol. 16; No. 4;

https://resolver.caltech.edu/CaltechAUTHORS:20190419-105736662

Torres-Padilla, Maria Elena; Zernicka-Goetz, Magdalena (2006) Role of TIF1α as a modulator of embryonic transcription in the mouse zygote Journal of Cell Biology; Vol. 174; No. 3;

https://resolver.caltech.edu/CaltechAUTHORS:20190419-105736755

Na, Jie; Zernicka-Goetz, Magdalena (2006) Asymmetric Positioning and Organization of the Meiotic Spindle of Mouse Oocytes Requires CDC42 Function Current Biology; Vol. 16; No. 12;

https://resolver.caltech.edu/CaltechAUTHORS:20190419-105736846

Richardson, Lucy; Torres-Padilla, Maria-Elena et al. (2006) Regionalised signalling within the extraembryonic ectoderm regulates anterior visceral endoderm positioning in the mouse embryo Mechanisms of Development; Vol. 123; No. 4;

https://resolver.caltech.edu/CaltechAUTHORS:20190419-105736940

Torres-Padilla, Maria-Elena; Bannister, Andrew J. et al. (2006) Dynamic distribution of the replacement histone variant H3.3 in the mouse oocyte and preimplantation embryos International Journal of Developmental Biology; Vol. 50; No. 5;

https://resolver.caltech.edu/CaltechAUTHORS:20190419-105737033

Soares, Miguel L.; Haraguchi, Seiki et al. (2005) Functional studies of signaling pathways in peri-implantation development of the mouse embryo by RNAi BMC Developmental Biology; Vol. 5;

https://resolver.caltech.edu/CaltechAUTHORS:20190419-105737131

Zernicka-Goetz, Magdalena (2005) Cleavage pattern and emerging asymmetry of the mouse embryo Nature Reviews. Molecular Cell Biology; Vol. 6; No. 12;

https://resolver.caltech.edu/CaltechAUTHORS:20190419-105737517

Moore, Catherine A.; Zernicka-Goetz, Magdalena (2005) PAR-1 and the microtubule-associated proteins CLASP2 and dynactin-p50 have specific localisation on mouse meiotic and first mitotic spindles Reproduction; Vol. 130; No. 3;

https://resolver.caltech.edu/CaltechAUTHORS:20190419-105737609

Piotrowska-Nitsche, Karolina; Zernicka-Goetz, Magdalena (2005) Spatial arrangement of individual 4-cell stage blastomeres and the order in which they are generated correlate with blastocyst pattern in the mouse embryo Mechanisms of Development; Vol. 122; No. 4;

https://resolver.caltech.edu/CaltechAUTHORS:20190419-105737708

Plusa, Berenika; Hadjantonakis, Anna-Katerina et al. (2005) The first cleavage of the mouse zygote predicts the blastocyst axis Nature; Vol. 434; No. 7031;

https://resolver.caltech.edu/CaltechAUTHORS:20190419-105737803

Plusa, Berenika; Frankenberg, Stephen et al. (2005) Downregulation of Par3 and aPKC function directs cells towards the ICM in the preimplantation mouse embryo Journal of Cell Science; Vol. 118; No. 3;

https://resolver.caltech.edu/CaltechAUTHORS:20190419-105738009

Piotrowska-Nitsche, Karolina; Perea-Gomez, Aitana et al. (2005) Four-cell stage mouse blastomeres have different developmental properties Development; Vol. 132; No. 3;

https://resolver.caltech.edu/CaltechAUTHORS:20190419-105737904

Carpenter, Lee; Zernicka-Goetz, Magdalena (2004) Directing pluripotent cell differentiation using "diced RNA" in transient transfection Genesis; Vol. 40; No. 3;

https://resolver.caltech.edu/CaltechAUTHORS:20190419-105738149

Zernicka-Goetz, Magdalena (2004) First cell fate decisions and spatial patterning in the early mouse embryo Seminars in Cell and Developmental Biology; Vol. 15; No. 5;

https://resolver.caltech.edu/CaltechAUTHORS:20190419-105738244

Gray, Dionne; Plusa, Berenika et al. (2004) First Cleavage of the Mouse Embryo Responds to Change in Egg Shape at Fertilization Current Biology; Vol. 14; No. 5;

https://resolver.caltech.edu/CaltechAUTHORS:20190419-105738331

Mesnard, Daniel; Filipe, Mario et al. (2004) The Anterior-Posterior Axis Emerges Respecting the Morphology of the Mouse Embryo that Changes and Aligns with the Uterus before Gastrulation Current Biology; Vol. 14; No. 3;

https://resolver.caltech.edu/CaltechAUTHORS:20190419-105738498

Wang, Q. Tian; Piotrowska, Karolina et al. (2004) A Genome-Wide Study of Gene Activity Reveals Developmental Signaling Pathways in the Preimplantation Mouse Embryo Developmental Cell; Vol. 6; No. 1;

https://resolver.caltech.edu/CaltechAUTHORS:20190419-105738586

Zernicka-Goetz, Magdalena; Pines, Jonathon (2003) Cell Lineage Analysis: Applications of Green Fluorescent Protein Developmental Biology Protocols; Vol. I; Series.Methods in Molecular Biology; No. 135;

https://resolver.caltech.edu/CaltechAUTHORS:20190422-101736360

Grabarek, J. B.; Wianny, F. et al. (2003) RNA Interference by Production of Short Hairpin dsRNA in ES Cells, Their Differentiated Derivatives, and in Somatic Cell Lines BioTechniques; Vol. 34; No. 4;

https://resolver.caltech.edu/CaltechAUTHORS:20190419-105738699

Durcova-Hills, Gabriela; Wianny, Florence et al. (2003) Developmental fate of embryonic germ cells (EGCs), in vivo and in vitro Differentiation; Vol. 71; No. 2;

https://resolver.caltech.edu/CaltechAUTHORS:20190419-105935323

Zernicka-Goetz, Magdalena (2003) Determining the first cleavage of the mouse zygote Reproductive BioMedicine Online; Vol. 6; No. 2;

https://resolver.caltech.edu/CaltechAUTHORS:20190422-100408460

Grabarek, Joanna B.; Zernicka-Goetz, Magdalena (2003) RNA Interference in Mammalian Systems - A Practical Approach Peroxisomal Disorders and Regulation of Genes; Series.Advances in Experimental Medicine and Biology ; No. 544; International Symposium on Peroxisomal Disorders and Regulation of Genes, 25-28 September 2002 , Ghent, Belgium

https://resolver.caltech.edu/CaltechAUTHORS:20190422-100408600

Piotrowska, Karolina; Zernicka-Goetz, Magdalena (2002) Early patterning of the mouse embryo -- contributions of sperm and egg Development; Vol. 129; No. 24;

https://resolver.caltech.edu/CaltechAUTHORS:20190422-100408698

Plusa, Berenika; Grabarek, Joanna B. et al. (2002) Site of the previous meiotic division defines cleavage orientation in the mouse embryo Nature Cell Biology; Vol. 4; No. 10;

https://resolver.caltech.edu/CaltechAUTHORS:20190422-100408799

Grabarek, Joanna B.; Plusa, Berenika et al. (2002) Efficient delivery of dsRNA into zona-enclosed mouse oocytes and preimplantation embryos by electroporation Genesis; Vol. 32; No. 4;

https://resolver.caltech.edu/CaltechAUTHORS:20190422-100408907

Plusa, Berenika; Piotrowska, Karolina et al. (2002) Sperm entry position provides a surface marker for the first cleavage plane of the mouse zygote Genesis; Vol. 32; No. 3;

https://resolver.caltech.edu/CaltechAUTHORS:20190422-100408995

Zernicka-Goetz, Magdalena (2002) Patterning of the embryo: the first spatial decisions in the life of a mouse Development; Vol. 129; No. 4;

https://resolver.caltech.edu/CaltechAUTHORS:20190422-100425160

Piotrowska, Karolina; Wianny, Florence et al. (2001) Blastomeres arising from the first cleavage division have distinguishable fates in normal mouse development Development; Vol. 128; No. 19;

https://resolver.caltech.edu/CaltechAUTHORS:20190422-100452455

Zernicka-Goetz, Magdalena; Pines, Jonathon (2001) Use of Green Fluorescent Protein in Mouse Embryos Methods; Vol. 24; No. 1;

https://resolver.caltech.edu/CaltechAUTHORS:20190422-101735870

Piotrowska, Karolina; Zernicka-Goetz, Magdalena (2001) Role for sperm in spatial patterning of the early mouse embryo Nature; Vol. 409; No. 6819;

https://resolver.caltech.edu/CaltechAUTHORS:20190422-101735996

Ciemerych, Maria Anna; Mesnard, Daniel et al. (2000) Animal and vegetal poles of the mouse egg predict the polarity of the embryonic axis, yet are nonessential for development Development; Vol. 127; No. 16;

https://resolver.caltech.edu/CaltechAUTHORS:20190422-101707437

Zernicka-Goetz, Magdalena (2000) Jumping the gun on mouse gene expression Nature; Vol. 405; No. 6788;

https://resolver.caltech.edu/CaltechAUTHORS:20190422-101736085

Grabarek, Joanna; Zernicka-Goetz, Magdalena (2000) Progression of mouse oocytes from metaphase I to metaphase II is inhibited by fusion with G2 cells Zygote; Vol. 8; No. 2;

https://resolver.caltech.edu/CaltechAUTHORS:20190422-101736181

Wianny, Florence; Zernicka-Goetz, Magdalena (2000) Specific interference with gene function by double-stranded RNA in early mouse development Nature Cell Biology; Vol. 2; No. 2;

https://resolver.caltech.edu/CaltechAUTHORS:20190422-101736270

Weber, R. J.; Pedersen, R. A. et al. (1999) Polarity of the mouse embryo is anticipated before implantation Development; Vol. 126; No. 24;

https://resolver.caltech.edu/CaltechAUTHORS:20190422-101708618

Zernicka-Goetz, Magdalena (1998) Fertile offspring derived from mammalian eggs lacking either animal or vegetal poles Development; Vol. 125; No. 23;

https://resolver.caltech.edu/CaltechAUTHORS:20190422-101709593

Wianny, Florence; Tavares, Álvaro et al. (1998) Mouse polo-like kinase 1 associates with the acentriolar spindle poles, meiotic chromosomes and spindle midzone during oocyte maturation Chromosoma; Vol. 107; No. 6-7;

https://resolver.caltech.edu/CaltechAUTHORS:20190422-101736448

Zernicka-Goetz, M.; Pines, J. et al. (1997) Following cell fate in the living mouse embryo Development; Vol. 124; No. 6;

https://resolver.caltech.edu/CaltechAUTHORS:20190422-101710597

Zernicka-Goetz, M.; Verlhac, M. H. et al. (1997) Protein phosphatases control MAP kinase activation and microtubule organization during rat oocyte maturation European journal of cell biology; Vol. 72; No. 1;

https://resolver.caltech.edu/CaltechAUTHORS:20190422-101711630

Zernicka-Goetz, M.; Pines, J. et al. (1996) An indelible lineage marker for Xenopus using a mutated green fluorescent protein Development; Vol. 122; No. 12;

https://resolver.caltech.edu/CaltechAUTHORS:20190422-101712629

Zernicka-Goetz, Magdalena; Ciemerych, Maria A. et al. (1995) Cytostatic factor inactivation is induced by a calcium-dependent mechanism present until the second cell cycle in fertilized but not in parthenogenetically activated mouse eggs Journal of Cell Science; Vol. 108; No. 2;

https://resolver.caltech.edu/CaltechAUTHORS:20190422-101713745

Zernicka-Goetz, Magdalena (1994) Activation of embryonic genes during preimplantation rat development Molecular Reproduction and Development; Vol. 38; No. 1;

https://resolver.caltech.edu/CaltechAUTHORS:20190422-101736535

Zernicka-Goetz, Magdalena; Maro, Bernard (1993) Okadaic Acid Affects Spindle Organization in Metaphase II-Arrested Rat Oocytes Experimental Cell Research; Vol. 207; No. 1;

https://resolver.caltech.edu/CaltechAUTHORS:20190422-101736624

Zernicka-Goetz, Magdalena; Kubiak, Jacek Z. et al. (1993) Cytoskeletal organization of rat oocytes during metaphase II arrest and following abortive activation: A study by confocal laser scanning microscopy Molecular Reproduction and Development; Vol. 35; No. 2;

https://resolver.caltech.edu/CaltechAUTHORS:20190422-101736718

Zernicka-Goetz, Magdalena; Weber, Michèle et al. (1993) Full activation of the rat oocyte by protein synthesis inhibition requires protein phosphatase activity International Journal of Developmental Biology; Vol. 37; No. 2;

https://resolver.caltech.edu/CaltechAUTHORS:20190422-101714782

Zernicka-Goetz, Magdalena (1991) Spontaneous and induced activation of rat oocytes Molecular Reproduction and Development; Vol. 28; No. 2;

https://resolver.caltech.edu/CaltechAUTHORS:20190422-101736808