Zernicka-Goetz, Magdalena

Article from CaltechAUTHORS

• Hadas, Ron and Rubinstein, Hernan, el al. (2024) Temporal BMP4 effects on mouse embryonic and extraembryonic development; Nature; Vol. 634; 652–661; 10.1038/s41586-024-07937-5
• Zernicka-Goetz, Magdalena and Hyun, Insoo (2024) Embryo models need consistent ethical oversight; Nature; Vol. 630; No. 8016; 305; 10.1038/d41586-024-01728-8
• Zhu, Meng and Meglicki, Maciej, el al. (2024) Tead4 and Tfap2c generate bipotency and a bistable switch in totipotent embryos to promote robust lineage diversification; Nature Structural & Molecular Biology; 10.1038/s41594-024-01311-9
• Junyent, Sergi and Meglicki, Maciej, el al. (2024) The first two blastomeres contribute unequally to the human embryo; Cell; Vol. 187; No. 11; 2838-2854.e17; 10.1016/j.cell.2024.04.029
• Sato, Nanami and Rosa, Viviane S., el al. (2024) Basal delamination during mouse gastrulation primes pluripotent cells for differentiation; Developmental Cell; Vol. 59; No. 10; 1252-1268.e13; 10.1016/j.devcel.2024.03.008
• Weatherbee, Bailey A. T. and Weberling, Antonia, el al. (2024) Distinct pathways drive anterior hypoblast specification in the implanting human embryo; Nature Cell Biology; 10.1038/s41556-024-01367-1
• Handford, Charlotte E and Junyent, Sergi, el al. (2024) Topical section: embryonic models (2023) for Current Opinion in Genetics & Development; Current Opinion in Genetics & Development; Vol. 84; 102134; 10.1016/j.gde.2023.102134
• Zernicka-Goetz, Magdalena (2023) The evolution of embryo models; Nature Methods; 10.1038/s41592-023-02077-6
• Lau, Kasey Y. C. and Amadei, Gianluca, el al. (2023) Assembly of complete mouse embryo models from embryonic and induced stem cell types in vitro; Nature Protocols; Vol. 18; No. 12; 3662-3689; 10.1038/s41596-023-00891-y
• Bao, Min and Cornwall-Scoones, Jake, el al. (2023) Stem cell-derived synthetic embryos self-assemble by exploiting cadherin codes and cortical tension; Nature Cell Biology; Vol. 24; No. 9; 1341-2349; PMCID PMC9481465; 10.1038/s41556-022-00984-y
• De Jonghe, Joachim and Kaminski, Tomasz S., el al. (2023) spinDrop: a droplet microfluidic platform to maximise single-cell sequencing information content; Nature Communications; Vol. 14; 4788; PMCID PMC10409775; 10.1038/s41467-023-40322-w
• Weatherbee, Bailey A. T. and Gantner, Carlos W., el al. (2023) A model of the post-implantation human embryo derived from pluripotent stem cells; Nature; 10.1038/s41586-023-06368-y
• Apostolou, Effie and Blau, Helen, el al. (2023) Progress and challenges in stem cell biology; Nature Cell Biology; Vol. 25; No. 2; 203-206; 10.1038/s41556-023-01087-y
• Amadei, Gianluca and Handford, Charlotte E., el al. (2022) Embryo model completes gastrulation to neurulation and organogenesis; Nature; Vol. 610; No. 7930; 143-153; PMCID PMC9534772; 10.1038/s41586-022-05246-3
• Lau, Kasey Y. C. and Rubinstein, Hernan, el al. (2022) Mouse embryo model derived exclusively from embryonic stem cells undergoes neurulation and heart development; Cell Stem Cell; Vol. 29; No. 10; 1445-1458.e8; PMCID PMC9648694; 10.1016/j.stem.2022.08.013
• Lau, Kasey Y. C. and Rubinstein, Hernan, el al. (2022) Mouse embryo model derived exclusively from embryonic stem cells undergoes neurulation and heart development; Cell Stem Cell; Vol. 29; No. 10; 1445-1458.e8; PMCID PMC9648694; 10.1016/j.stem.2022.08.013
• Bao, Min and Cornwall-Scoones, Jake, el al. (2022) Stem-cell-based human and mouse embryo models; Current Opinion in Genetics and Development; Vol. 76; 101970; PMCID PMC10309046; 10.1016/j.gde.2022.101970
• Bao, Min and Cornwall-Scoones, Jake, el al. (2022) Stem cell-derived synthetic embryos self-assemble by exploiting cadherin codes and cortical tension; Nature Cell Biology; Vol. 24; No. 9; 1341-1349; PMCID PMC9481465; 10.1038/s41556-022-00984-y
• Liang, Xuan and Weberling, Antonia, el al. (2022) E-cadherin mediates apical membrane initiation site localisation during de novo polarisation of epithelial cavities; EMBO Journal; Art No. e111021; 10.15252/embj.2022111021
• Shen, Cheng and Lamba, Adiyant, el al. (2022) Stain-free detection of embryo polarization using deep learning; Scientific Reports; Vol. 12; Art. No. 2404; 10.1038/s41598-022-05990-6
• Duethorn, Binyamin and Groll, Fabian, el al. (2022) Lima1 mediates the pluripotency control of membrane dynamics and cellular metabolism; Nature Communications; Vol. 13; Art. No. 610; PMCID PMC8807836; 10.1038/s41467-022-28139-5
• Rawlings, Thomas M. and Makwana, Komal, el al. (2021) Modelling the impact of decidual senescence on embryo implantation in human endometrial assembloids; eLife; Vol. 10; Art. No. e69603; PMCID PMC8523170; 10.7554/elife.69603
• Zhu, Meng and Shahbazi, Marta, el al. (2021) Human embryo polarization requires PLC signaling to mediate trophectoderm specification; eLife; Vol. 10; Art. No. e65068; 10.7554/eLife.65068
• Sozen, Berna and Jorgensen, Victoria, el al. (2021) Reconstructing aspects of human embryogenesis with pluripotent stem cells; Nature Communications; Vol. 12; Art. No. 5550; PMCID PMC8455697; 10.1038/s41467-021-25853-4
• Mackinlay, Kirsty M. L. and Weatherbee, Bailey A. T., el al. (2021) An in vitro stem cell model of human epiblast and yolk sac interaction; eLife; Vol. 10; Art. No. e63930; PMCID PMC8370770; 10.7554/elife.63930
• Molè, Matteo A. and Coorens, Tim H. H., el al. (2021) A single cell characterisation of human embryogenesis identifies pluripotency transitions and putative anterior hypoblast centre; Nature Communications; Vol. 12; Art. No. 3679; 10.1038/s41467-021-23758-w
• Weatherbee, Bailey A. T. and Cui, Tongtong, el al. (2021) Modeling human embryo development with embryonic and extra-embryonic stem cells; Developmental Biology; Vol. 474; 91-99; PMCID PMC8232073; 10.1016/j.ydbio.2020.12.010
• Cornwall-Scoones, Jake and Zernicka-Goetz, Magdalena (2021) Unifying synthetic embryology; Developmental Biology; Vol. 474; 1-4; PMCID PMC8257322; 10.1016/j.ydbio.2021.03.007
• Sozen, Berna and Cornwall-Scoones, Jake, el al. (2021) The dynamics of morphogenesis in stem cell-based embryology: Novel insights for symmetry breaking; Developmental Biology; Vol. 474; 82-90; PMCID PMC8259461; 10.1016/j.ydbio.2020.12.005
• Orietti, Lorenzo C. and Rosa, Viviane Souza, el al. (2021) Embryo Size Regulates the Timing and Mechanism of Pluripotent Tissue Morphogenesis; Stem Cell Reports; Vol. 16; No. 5; 1182-1196; PMCID PMC8185375; 10.1016/j.stemcr.2020.09.004
• Guo, Jianying and Wang, Peizhe, el al. (2021) Machine learning-assisted high-content analysis of pluripotent stem cell-derived embryos in vitro; Stem Cell Reports; Vol. 16; No. 5; 1331-1346; PMCID PMC8185434; 10.1016/j.stemcr.2021.03.018
• Shi, Junchao and Zhang, Yunfang, el al. (2021) PANDORA-seq expands the repertoire of regulatory small RNAs by overcoming RNA modifications; Nature Cell Biology; Vol. 23; No. 4; 424-436; 10.1038/s41556-021-00652-7
• Molè, Matteo Amitaba and Weberling, Antonia, el al. (2021) Integrin β1 coordinates survival and morphogenesis of the embryonic lineage upon implantation and pluripotency transition; Cell Reports; Vol. 34; No. 10; Art. No. 108834; PMCID PMC7966855; 10.1016/j.celrep.2021.108834
• Amadei, Gianluca and Lau, Kasey Y. C., el al. (2021) Inducible Stem-Cell-Derived Embryos Capture Mouse Morphogenetic Events In Vitro; Developmental Cell; Vol. 56; No. 3; 366-382; PMCID PMC7883308; 10.1016/j.devcel.2020.12.004
• Sozen, Berna and Demir, Necdet, el al. (2021) BMP signalling is required for extra-embryonic ectoderm development during pre-to-post-implantation transition of the mouse embryo; Developmental Biology; Vol. 470; 84-94; PMCID PMC8219371; 10.1016/j.ydbio.2020.11.005
• Weberling, Antonia and Zernicka-Goetz, Magdalena (2021) Trophectoderm mechanics direct epiblast shape upon embryo implantation; Cell Reports; Vol. 34; No. 3; Art. No. 108655; PMCID PMC7816124; 10.1016/j.celrep.2020.108655
• Zhu, Meng and Cornwall-Scoones, Jake, el al. (2020) Developmental clock and mechanism of de novo polarization of the mouse embryo; Science; Vol. 370; No. 6522; Art. No. eabd2703; PMCID PMC8210885; 10.1126/science.abd2703
• Zhu, Meng and Zernicka-Goetz, Magdalena (2020) Principles of Self-Organization of the Mammalian Embryo; Cell; Vol. 183; No. 6; 1467-1478; PMCID PMC8212876; 10.1016/j.cell.2020.11.003
• Lynch, Cian J. and Bernad, Raquel, el al. (2020) Global hyperactivation of enhancers stabilizes human and mouse naive pluripotency through inhibition of CDK8/19 Mediator kinases; Nature Cell Biology; Vol. 22; No. 10; 1223-1238; 10.1038/s41556-020-0573-1
• Cornwall-Scoones, Jake and Zernicka-Goetz, Magdalena (2020) Starting life in space; National Science Review; Vol. 7; No. 9; 1447-1448; 10.1093/nsr/nwaa102
• Shahbazi, Marta N. and Wang, Tianren, el al. (2020) Developmental potential of aneuploid human embryos cultured beyond implantation; Nature Communications; Vol. 11; Art. No. 3987; PMCID PMC7418029; 10.1038/s41467-020-17764-7
• Weatherbee, Bailey A. T. and Glover, David M., el al. (2020) Expression of SARS-CoV-2 receptor ACE2 and the protease TMPRSS2 suggests susceptibility of the human embryo in the first trimester; Open Biology; Vol. 10; No. 8; 200162; PMCID PMC7479935; 10.1098/rsob.200162
• Kyprianou, Christos and Christodoulou, Neophytos, el al. (2020) Basement membrane remodelling regulates mouse embryogenesis; Nature; Vol. 582; No. 7811; 253-258; PMCID PMC7308173; 10.1038/s41586-020-2264-2
• Singla, Shruti and Iwamoto-Stohl, Lisa K., el al. (2020) Autophagy-mediated apoptosis eliminates aneuploid cells in a mouse model of chromosome mosaicism; Nature Communications; Vol. 11; Art. No. 2958; PMCID PMC7290028; 10.1038/s41467-020-16796-3
• Zhu, Meng and Zernicka-Goetz, Magdalena (2020) Living a Sweet Life: Glucose Instructs Cell Fate in the Mouse Embryo; Developmental Cell; Vol. 53; No. 1; 1-2; 10.1016/j.devcel.2020.03.012
• Zhu, Meng and Zernicka-Goetz, Magdalena (2020) Building an apical domain in the early mouse embryo: Lessons, challenges and perspectives; Current Opinion in Cell Biology; Vol. 62; 144-149; 10.1016/j.ceb.2019.11.005
• Sozen, Berna and Cox, Andy L., el al. (2019) Self-Organization of Mouse Stem Cells into an Extended Potential Blastoid; Developmental Cell; Vol. 51; No. 6; 698-712; PMCID PMC10291877; 10.1016/j.devcel.2019.11.014
• Aloia, Luigi and McKie, Mikel Alexander, el al. (2019) Epigenetic remodelling licences adult cholangiocytes for organoid formation and liver regeneration; Nature Cell Biology; Vol. 21; No. 11; 1321-1333; PMCID PMC6940196; 10.1038/s41556-019-0402-6
• Anikeeva, Polina and Cissé, Ibrahim I., el al. (2019) Voices in methods development; Nature Methods; Vol. 16; No. 10; 945-951; PMCID PMC7075469; 10.1038/s41592-019-0585-6
• Christodoulou, Neophytos and Weberling, Antonia, el al. (2019) Morphogenesis of extra-embryonic tissues directs the remodelling of the mouse embryo at implantation; Nature Communications; Vol. 10; Art. No. 3557; PMCID PMC6686005; 10.1038/s41467-019-11482-5
• Antonica, Francesco and Orietti, Lorenzo Carlo, el al. (2019) Concerted cell divisions in embryonic visceral endoderm guide anterior visceral endoderm migration; Developmental Biology; Vol. 450; No. 2; 132-140; PMCID PMC6553843; 10.1016/j.ydbio.2019.03.016
• Shahbazi, Marta N. and Siggia, Eric D., el al. (2019) Self-organization of stem cells into embryos: A window on early mammalian development; Science; Vol. 364; No. 6444; 948-951; 10.1126/science.aax0164
• Rivron, Nicolas and Pera, Martin, el al. (2018) Debate ethics of embryo models from stem cells; Nature; Vol. 564; No. 7735; 183-185; 10.1038/d41586-018-07663-9
• Hupalowska, Anna and Jedrusik, Agnieszka, el al. (2018) CARM1 and Paraspeckles Regulate Pre-implantation Mouse Embryo Development; Cell; Vol. 175; No. 7; 1902-1916.e13; PMCID PMC6292842; 10.1016/j.cell.2018.11.027
• Christodoulou, Neophytos and Kyprianou, Christos, el al. (2018) Sequential formation and resolution of multiple rosettes drive embryo remodelling after implantation; Nature Cell Biology; Vol. 20; No. 11; 1278-1289; 10.1038/s41556-018-0211-3
• Sozen, Berna and Amadei, Gianluca, el al. (2018) Self-assembly of embryonic and two extra-embryonic stem cell types into gastrulating embryo-like structures; Nature Cell Biology; Vol. 20; No. 8; 979-989; 10.1038/s41556-018-0147-7
• Shahbazi, Marta N. and Zernicka-Goetz, Magdalena (2018) Deconstructing and reconstructing the mouse and human early embryo; Nature Cell Biology; Vol. 20; No. 8; 878-887; 10.1038/s41556-018-0144-x
• Harrison, Sarah Ellys and Sozen, Berna, el al. (2018) In vitro generation of mouse polarized embryo-like structures from embryonic and trophoblast stem cells; Nature Protocols; Vol. 13; No. 7; 1586-1602; 10.1038/s41596-018-0005-x
• Chen, Qi and Shi, Junchao, el al. (2018) Tracing the origin of heterogeneity and symmetry breaking in the early mammalian embryo; Nature Communications; Vol. 9; Art. No. 1819; PMCID PMC5940674; 10.1038/s41467-018-04155-2
• Papaspyropoulos, Angelos and Bradley, Leanne, el al. (2018) RASSF1A uncouples Wnt from Hippo signalling and promotes YAP mediated differentiation via p73; Nature Communications; Vol. 9; Art. No. 424; PMCID PMC5789973; 10.1038/s41467-017-02786-5
• Strauss, Bernhard and Harrison, Andrew, el al. (2018) Cyclin B1 is essential for mitosis in mouse embryos, and its nuclear export sets the time for mitosis; Journal of Cell Biology; Vol. 217; No. 1; 179-193; PMCID PMC5748970; 10.1083/jcb.201612147
• Shahbazi, Marta N. and Scialdone, Antonio, el al. (2017) Pluripotent state transitions coordinate morphogenesis in mouse and human embryos; Nature; Vol. 552; No. 7684; 239-243; PMCID PMC5768241; 10.1038/nature24675
• Bury, Leah and Coelho, Paula A., el al. (2017) Plk4 and Aurora A cooperate in the initiation of acentriolar spindle assembly in mammalian oocytes; Journal of Cell Biology; Vol. 216; No. 11; 3571-3590; PMCID PMC5674873; 10.1083/jcb.201606077
• Hurlbut, J. Benjamin and Hyun, Insoo, el al. (2017) Revisiting the Warnock rule; Nature Biotechnology; Vol. 35; No. 11; 1029-1042; 10.1038/nbt.4015
• Zhu, Meng and Leung, Chuen Yan, el al. (2017) Actomyosin polarisation through PLC-PKC triggers symmetry breaking of the mouse embryo; Nature Communications; Vol. 8; Art. No. 921; PMCID PMC5640629; 10.1038/s41467-017-00977-8
• Ajduk, Anna and Strauss, Bernhard, el al. (2017) Delayed APC/C activation extends the first mitosis of mouse embryos; Scientific Reports; Vol. 7; Art. No. 9682; PMCID PMC5575289; 10.1038/s41598-017-09526-1
• Goolam, Mubeen and Zernicka-Goetz, Magdalena (2017) The chromatin modifier Satb1 regulates cell fate through Fgf signalling in the early mouse embryo; Development; Vol. 144; No. 8; 1450-1461; PMCID PMC5399666; 10.1242/dev.144139
• Harrison, Sarah Ellys and Sozen, Berna, el al. (2017) Assembly of embryonic and extraembryonic stem cells to mimic embryogenesis in vitro; Science; Vol. 356; No. 6334; Art. No. eaal1810; 10.1126/science.aal1810
• Zernicka-Goetz, Magdalena (2016) Andrzej K. Tarkowski 1933–2016; Nature Cell Biology; Vol. 18; No. 12; 1261; 10.1038/ncb3446
• Ajduk, Anna and Zernicka-Goetz, Magdalena (2016) Polarity and cell division orientation in the cleavage embryo: from worm to human; Molecular Human Reproduction; Vol. 22; No. 10; 691-703; PMCID PMC5062000; 10.1093/molehr/gav068
• Shahbazi, Marta N. and Jedrusik, Agnieszka, el al. (2016) Self-organization of the human embryo in the absence of maternal tissues; Nature Cell Biology; Vol. 18; No. 6; 700-708; PMCID PMC5049689; 10.1038/ncb3347
• Deglincerti, Alessia and Croft, Gist F., el al. (2016) Self-organization of the in vitro attached human embryo; Nature; Vol. 533; No. 7602; 251-254; 10.1038/nature17948
• Panamarova, Maryna and Cox, Andy, el al. (2016) The BAF chromatin remodelling complex is an epigenetic regulator of lineage specification in the early mouse embryo; Development; Vol. 143; No. 8; 1271-1283; PMCID PMC4852518; 10.1242/dev.131961
• Bolton, Helen and Graham, Sarah J. L., el al. (2016) Mouse model of chromosome mosaicism reveals lineage-specific depletion of aneuploid cells and normal developmental potential; Nature Communications; Vol. 7; Art. No. 11165; PMCID PMC4820631; 10.1038/ncomms11165
• Goolam, Mubeen and Scialdone, Antonio, el al. (2016) Heterogeneity in Oct4 and Sox2 Targets Biases Cell Fate in 4-Cell Mouse Embryos; Cell; Vol. 165; No. 1; 61-74; PMCID PMC4819611; 10.1016/j.cell.2016.01.047
• Coelho, Paula A. and Bury, Leah, el al. (2015) Over-expression of Plk4 induces centrosome amplification, loss of primary cilia and associated tissue hyperplasia in the mouse; Open Biology; Vol. 5; No. 12; Art. No. 150209; PMCID PMC4703062; 10.1098/rsob.150209
• Bedzhov, Ivan and Bialecka, Monika, el al. (2015) Development of the anterior-posterior axis is a self-organizing process in the absence of maternal cues in the mouse embryo; Cell Research; Vol. 25; No. 12; 1368-1371; PMCID PMC4670986; 10.1038/cr.2015.104
• Leung, Chuen Yan and Zernicka-Goetz, Magdalena (2015) Mapping the journey from totipotency to lineage specification in the mouse embryo; Current Opinion in Genetics and Development; Vol. 34; 71-76; 10.1016/j.gde.2015.08.002
• Macaulay, Iain C. and Haerty, Wilfried, el al. (2015) G&T-seq: parallel sequencing of single-cell genomes and transcriptomes; Nature Methods; Vol. 12; No. 6; 519-522; 10.1038/nmeth.3370
• Bedzhov, Ivan and Zernicka-Goetz, Magdalena (2015) Cell death and morphogenesis during early mouse development: Are they interconnected?; Bioessays; Vol. 37; No. 4; 372-378; PMCID PMC4409078; 10.1002/bies.201400147
• Jedrusik, Agnieszka and Cox, Andy, el al. (2015) Maternal-zygotic knockout reveals a critical role of Cdx2 in the morula to blastocyst transition; Developmental Biology; Vol. 398; No. 2; 147-152; PMCID PMC4319684; 10.1016/j.ydbio.2014.12.004
• Graham, Sarah J. L. and Wicher, Krzysztof B., el al. (2014) BMP signalling regulates the pre-implantation development of extra-embryonic cell lineages in the mouse embryo; Nature Communications; Vol. 5; Art. No. 5667; PMCID PMC4338527; 10.1038/ncomms6667
• Bedzhov, Ivan and Graham, Sarah J. L., el al. (2014) Developmental plasticity, cell fate specification and morphogenesis in the early mouse embryo; Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences; Vol. 369; No. 1657; Art. No. 20130538; PMCID PMC4216461; 10.1098/rstb.2013.0538
• Zernicka-Goetz, Magdalena and Hadjantonakis, Anna-Katerina (2014) From pluripotency to differentiation: laying foundations for the body pattern in the mouse embryo; Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences; Vol. 369; No. 1657; Art. No. 20130535; PMCID PMC4216458; 10.1098/rstb.2013.0535
• Bedzhov, Ivan and Leung, Chuen Yan, el al. (2014) In vitro culture of mouse blastocysts beyond the implantation stages; Nature Protocols; Vol. 9; No. 12; 2732-2739; 10.1038/nprot.2014.186
• Ajduk, Anna and Biswas Shivhare, Sourima, el al. (2014) The basal position of nuclei is one pre-requisite for asymmetric cell divisions in the early mouse embryo; Developmental Biology; Vol. 392; No. 2; 133-140; PMCID PMC4111899; 10.1016/j.ydbio.2014.05.009
• Rosenthal, Nadia and Zernicka-Goetz, Magdalena (2014) A tribute to Sir John Gurdon; Differentiation; Vol. 88; No. 1; 1-2; 10.1016/j.diff.2014.11.001
• Christophorou, Maria A. and Castelo-Branco, Gonçalo, el al. (2014) Citrullination regulates pluripotency and histone H1 binding to chromatin; Nature; Vol. 507; No. 7490; 104-108; PMCID PMC4843970; 10.1038/nature12942
• Bedzhov, Ivan and Zernicka-Goetz, Magdalena (2014) Self-Organizing Properties of Mouse Pluripotent Cells Initiate Morphogenesis upon Implantation; Cell; Vol. 156; No. 5; 1032-1044; PMCID PMC3991392; 10.1016/j.cell.2014.01.023
• Coelho, Paula A. and Bury, Leah, el al. (2013) Spindle Formation in the Mouse Embryo Requires Plk4 in the Absence of Centrioles; Developmental Cell; Vol. 27; No. 5; 586-597; PMCID PMC3898710; 10.1016/j.devcel.2013.09.029
• Morris, Samantha A. and Graham, Sarah J. L., el al. (2013) The differential response to Fgf signalling in cells internalized at different times influences lineage segregation in preimplantation mouse embryos; Open Biology; Vol. 3; No. 11; Art. No. 130104; PMCID PMC3843820; 10.1098/rsob.130104
• Ajduk, Anna and Zernicka-Goetz, Magdalena (2013) Quality control of embryo development; Molecular Aspects of Medicine; Vol. 34; No. 5; 903-918; 10.1016/j.mam.2013.03.001
• Duan, En-kui and Wang, Haibin, el al. (2013) Introduction to the special issue "Molecular Players in Early Pregnancy"; Molecular Aspects of Medicine; Vol. 34; No. 5; vi-vii; 10.1016/s0098-2997(13)00054-x
• Leung, Chuen Yan and Zernicka-Goetz, Magdalena (2013) Angiomotin prevents pluripotent lineage differentiation in mouse embryos via Hippo pathway-dependent and -independent mechanisms; Nature Communications; Vol. 4; Art. No. 2251; PMCID PMC3741640; 10.1038/ncomms3251
• Skamagki, Maria and Wicher, Krzysztof B., el al. (2013) Asymmetric Localization of Cdx2 mRNA during the First Cell-Fate Decision in Early Mouse Development; Cell Reports; Vol. 3; No. 2; 442-457; PMCID PMC3607255; 10.1016/j.celrep.2013.01.006
• Zernicka-Goetz, Magdalena (2013) Development: Do Mouse Embryos Play Dice?; Current Biology; Vol. 23; No. 1; R15-R17; 10.1016/j.cub.2012.10.032
• Pasque, Vincent and Radzisheuskaya, Aliaksandra, el al. (2012) Histone variant macroH2A marks embryonic differentiation in vivo and acts as an epigenetic barrier to induced pluripotency; Journal of Cell Science; Vol. 125; No. 24; 6094-6104; PMCID PMC3585521; 10.1242/jcs.113019
• Morris, Samantha A. and Guo, Yu, el al. (2012) Developmental Plasticity Is Bound by Pluripotency and the Fgf and Wnt Signaling Pathways; Cell Reports; Vol. 2; No. 4; 756-765; PMCID PMC3607220; 10.1016/j.celrep.2012.08.029
• Lee, Yun Hwa and Ma, Hui, el al. (2012) Protein Arginine Methyltransferase 6 Regulates Embryonic Stem Cell Identity; Stem Cells and Development; Vol. 21; No. 14; 2613-2622; PMCID PMC5729635; 10.1089/scd.2011.0330
• Ajduk, Anna and Zernicka-Goetz, Magdalena (2012) Advances in embryo selection methods; F1000 Biology Reports; Vol. 4; Art. No. 11; PMCID PMC3369238; 10.3410/b4-11
• Swann, Karl and Windsor, Shane, el al. (2012) Phospholipase C-ζ-induced Ca^(2+) oscillations cause coincident cytoplasmic movements in human oocytes that failed to fertilize after intracytoplasmic sperm injection; Fertility and Sterility; Vol. 97; No. 3; 742-747; PMCID PMC3334266; 10.1016/j.fertnstert.2011.12.013
• Morris, Samantha A. and Grewal, Seema, el al. (2012) Dynamics of anterior–posterior axis formation in the developing mouse embryo; Nature Communications; Vol. 3; Art. No. 673; PMCID PMC3293425; 10.1038/ncomms1671
• Ajduk, Anna and Ilozue, Tagbo, el al. (2011) Rhythmic actomyosin-driven contractions induced by sperm entry predict mammalian embryo viability; Nature Communications; Vol. 2; Art. No. 417; PMCID PMC3265380; 10.1038/ncomms1424
• Zernicka-Goetz, Magdalena (2011) Proclaiming fate in the early mouse embryo; Nature Cell Biology; Vol. 13; No. 2; 112-114; 10.1038/ncb0211-112
• Sharif, Bedra and Na, Jie, el al. (2010) The chromosome passenger complex is required for fidelity of chromosome transmission and cytokinesis in meiosis of mouse oocytes; Journal of Cell Science; Vol. 123; No. 24; 4292-4300; PMCID PMC2995614; 10.1242/jcs.067447
• Zernicka-Goetz, Magdalena and Huang, Sui (2010) Stochasticity versus determinism in development: a false dichotomy?; Nature Reviews. Genetics; Vol. 11; No. 11; 743-744; 10.1038/nrg2886
• Bruce, Alexander W. and Zernicka-Goetz, Magdalena (2010) Developmental control of the early mammalian embryo: competition among heterogeneous cells that biases cell fate; Current Opinion in Genetics and Development; Vol. 20; No. 5; 485-491; 10.1016/j.gde.2010.05.006
• Jedrusik, Agnieszka and Bruce, Alexander W., el al. (2010) Maternally and zygotically provided Cdx2 have novel and critical roles for early development of the mouse embryo; Developmental Biology; Vol. 344; No. 1; 66-78; PMCID PMC2954319; 10.1016/j.ydbio.2010.04.017
• Parfitt, David-Emlyn and Zernicka-Goetz, Magdalena (2010) Epigenetic Modification Affecting Expression of Cell Polarity and Cell Fate Genes to Regulate Lineage Specification in the Early Mouse Embryo; Molecular Biology of the Cell; Vol. 21; No. 15; 2649-2660; PMCID PMC2912351; 10.1091/mbc.e10-01-0053
• Morris, Samantha A. and Teo, Roy T. Y., el al. (2010) Origin and formation of the first two distinct cell types of the inner cell mass in the mouse embryo; Proceedings of the National Academy of Sciences of the United States of America; Vol. 107; No. 14; 6364-6369; PMCID PMC2852013; 10.1073/pnas.0915063107
• Wu, Qiang and Bruce, Alexander W., el al. (2009) CARM1 Is Required in Embryonic Stem Cells to Maintain Pluripotency and Resist Differentiation; Stem Cells; Vol. 27; No. 11; 2637-2645; PMCID PMC4135545; 10.1002/stem.131
• Meilhac, Sigolène M. and Adams, Richard J., el al. (2009) Active cell movements coupled to positional induction are involved in lineage segregation in the mouse blastocyst; Developmental Biology; Vol. 331; No. 2; 210-221; PMCID PMC3353123; 10.1016/j.ydbio.2009.04.036
• Zernicka-Goetz, Magdalena and Morris, Samantha A., el al. (2009) Making a firm decision: multifaceted regulation of cell fate in the early mouse embryo; Nature Reviews. Genetics; Vol. 10; No. 7; 467-477; 10.1038/nrg2564
• Jedrusik, Agnieszka and Parfitt, David-Emlyn, el al. (2008) Role of Cdx2 and cell polarity in cell allocation and specification of trophectoderm and inner cell mass in the mouse embryo; Genes and Development; Vol. 22; No. 19; 2692-2706; PMCID PMC2559904; 10.1101/gad.486108
• Lykke-Andersen, Karin and Gilchrist, Michael J., el al. (2008) Maternal Argonaute 2 Is Essential for Early Mouse Development at the Maternal-Zygotic Transition; Molecular Biology of the Cell; Vol. 19; No. 10; 4383-4392; PMCID PMC2555945; 10.1091/mbc.e08-02-0219
• Soares, Miguel L. and Torres-Padilla, Maria-Elena, el al. (2008) Bone morphogenetic protein 4 signaling regulates development of the anterior visceral endoderm in the mouse embryo; Development, Growth & Differentiation; Vol. 50; No. 7; 615-621; PMCID PMC3342679; 10.1111/j.1440-169x.2008.01059.x
• Adjaye, James A. and Byskov, Anne G., el al. (2008) Pluripotency and differentiation in embryos and stem cells - Pavia, 17-18 January 2008; International Journal of Developmental Biology; Vol. 52; No. 7; 801-809; 10.1387/ijdb.082695ja
• Bischoff, Marcus and Parfitt, David-Emlyn, el al. (2008) Formation of the embryonic-abembryonic axis of the mouse blastocyst: relationships between orientation of early cleavage divisions and pattern of symmetric/asymmetric divisions; Development; Vol. 135; No. 5; 953-962; PMCID PMC2655627; 10.1242/dev.014316
• Torres-Padilla, Maria-Elena and Richardson, Lucy, el al. (2007) The anterior visceral endoderm of the mouse embryo is established from both preimplantation precursor cells and by de novo gene expression after implantation; Developmental Biology; Vol. 309; No. 1; 97-112; PMCID PMC3353121; 10.1016/j.ydbio.2007.06.020
• Perea-Gomez, Aitana and Meilhac, Sigolène M., el al. (2007) Regionalisation of the mouse visceral endoderm as the blastocyst transforms into the egg cylinder; BMC Developmental Biology; Vol. 7; Art. No. 96; PMCID PMC1978209; 10.1186/1471-213x-7-96
• Frankenberg, Stephen and Smith, Lee, el al. (2007) Novel gene expression patterns along the proximo-distal axis of the mouse embryo before gastrulation; BMC Developmental Biology; Vol. 7; Art. No. 8; PMCID PMC1821012; 10.1186/1471-213x-7-8
• Na, Jie and Lykke-Andersen, Karin, el al. (2007) Dishevelled proteins regulate cell adhesion in mouse blastocyst and serve to monitor changes in Wnt signaling; Developmental Biology; Vol. 302; No. 1; 40-49; PMCID PMC3353122; 10.1016/j.ydbio.2006.08.036
• Torres-Padilla, Maria-Elena and Parfitt, David-Emlyn, el al. (2007) Histone arginine methylation regulates pluripotency in the early mouse embryo; Nature; Vol. 445; No. 7124; 214-218; PMCID PMC3353120; 10.1038/nature05458
• Zernicka-Goetz, Magdalena (2006) The first cell-fate decisions in the mouse embryo: destiny is a matter of both chance and choice; Current Opinion in Genetics and Development; Vol. 16; No. 4; 406-412; 10.1016/j.gde.2006.06.011
• Torres-Padilla, Maria Elena and Zernicka-Goetz, Magdalena (2006) Role of TIF1α as a modulator of embryonic transcription in the mouse zygote; Journal of Cell Biology; Vol. 174; No. 3; 329-338; PMCID PMC2064229; 10.1083/jcb.200603146
• Na, Jie and Zernicka-Goetz, Magdalena (2006) Asymmetric Positioning and Organization of the Meiotic Spindle of Mouse Oocytes Requires CDC42 Function; Current Biology; Vol. 16; No. 12; 1249-1254; 10.1016/j.cub.2006.05.023
• Richardson, Lucy and Torres-Padilla, Maria-Elena, el al. (2006) Regionalised signalling within the extraembryonic ectoderm regulates anterior visceral endoderm positioning in the mouse embryo; Mechanisms of Development; Vol. 123; No. 4; 288-296; 10.1016/j.mod.2006.01.004
• Torres-Padilla, Maria-Elena and Bannister, Andrew J., el al. (2006) Dynamic distribution of the replacement histone variant H3.3 in the mouse oocyte and preimplantation embryos; International Journal of Developmental Biology; Vol. 50; No. 5; 455-461; 10.1387/ijdb.052073mt
• Soares, Miguel L. and Haraguchi, Seiki, el al. (2005) Functional studies of signaling pathways in peri-implantation development of the mouse embryo by RNAi; BMC Developmental Biology; Vol. 5; Art. No. 28; PMCID PMC1363358; 10.1186/1471-213x-5-28
• Zernicka-Goetz, Magdalena (2005) Cleavage pattern and emerging asymmetry of the mouse embryo; Nature Reviews. Molecular Cell Biology; Vol. 6; No. 12; 919-928; 10.1038/nrm1782
• Moore, Catherine A. and Zernicka-Goetz, Magdalena (2005) PAR-1 and the microtubule-associated proteins CLASP2 and dynactin-p50 have specific localisation on mouse meiotic and first mitotic spindles; Reproduction; Vol. 130; No. 3; 311-320; 10.1530/rep.1.00651
• Piotrowska-Nitsche, Karolina and Zernicka-Goetz, Magdalena (2005) Spatial arrangement of individual 4-cell stage blastomeres and the order in which they are generated correlate with blastocyst pattern in the mouse embryo; Mechanisms of Development; Vol. 122; No. 4; 487-500; 10.1016/j.mod.2004.11.014
• Plusa, Berenika and Hadjantonakis, Anna-Katerina, el al. (2005) The first cleavage of the mouse zygote predicts the blastocyst axis; Nature; Vol. 434; No. 7031; 391-395; 10.1038/nature03388
• Plusa, Berenika and Frankenberg, Stephen, el al. (2005) Downregulation of Par3 and aPKC function directs cells towards the ICM in the preimplantation mouse embryo; Journal of Cell Science; Vol. 118; No. 3; 505-515; 10.1242/jcs.01666
• Piotrowska-Nitsche, Karolina and Perea-Gomez, Aitana, el al. (2005) Four-cell stage mouse blastomeres have different developmental properties; Development; Vol. 132; No. 3; 479-490; 10.1242/dev.01602
• Carpenter, Lee and Zernicka-Goetz, Magdalena (2004) Directing pluripotent cell differentiation using "diced RNA" in transient transfection; Genesis; Vol. 40; No. 3; 157-163; 10.1002/gene.20078
• Zernicka-Goetz, Magdalena (2004) First cell fate decisions and spatial patterning in the early mouse embryo; Seminars in Cell and Developmental Biology; Vol. 15; No. 5; 563-572; 10.1016/j.semcdb.2004.04.004
• Gray, Dionne and Plusa, Berenika, el al. (2004) First Cleavage of the Mouse Embryo Responds to Change in Egg Shape at Fertilization; Current Biology; Vol. 14; No. 5; 397-405; 10.1016/j.cub.2004.02.031
• Mesnard, Daniel and Filipe, Mario, el al. (2004) The Anterior-Posterior Axis Emerges Respecting the Morphology of the Mouse Embryo that Changes and Aligns with the Uterus before Gastrulation; Current Biology; Vol. 14; No. 3; 184-196; 10.1016/j.cub.2004.01.026
• Wang, Q. Tian and Piotrowska, Karolina, el al. (2004) A Genome-Wide Study of Gene Activity Reveals Developmental Signaling Pathways in the Preimplantation Mouse Embryo; Developmental Cell; Vol. 6; No. 1; 133-144; 10.1016/s1534-5807(03)00404-0
• Grabarek, J. B. and Wianny, F., el al. (2003) RNA Interference by Production of Short Hairpin dsRNA in ES Cells, Their Differentiated Derivatives, and in Somatic Cell Lines; BioTechniques; Vol. 34; No. 4; 734-744; 10.2144/03344st02
• Durcova-Hills, Gabriela and Wianny, Florence, el al. (2003) Developmental fate of embryonic germ cells (EGCs), in vivo and in vitro; Differentiation; Vol. 71; No. 2; 135-141; 10.1046/j.1432-0436.2003.710204.x
• Zernicka-Goetz, Magdalena (2003) Determining the first cleavage of the mouse zygote; Reproductive BioMedicine Online; Vol. 6; No. 2; 160-163; 10.1016/s1472-6483(10)61704-x
• Piotrowska, Karolina and Zernicka-Goetz, Magdalena (2002) Early patterning of the mouse embryo -- contributions of sperm and egg; Development; Vol. 129; No. 24; 5803-5813; 10.1242/dev.00170
• Plusa, Berenika and Grabarek, Joanna B., el al. (2002) Site of the previous meiotic division defines cleavage orientation in the mouse embryo; Nature Cell Biology; Vol. 4; No. 10; 811-815; 10.1038/ncb860
• Grabarek, Joanna B. and Plusa, Berenika, el al. (2002) Efficient delivery of dsRNA into zona-enclosed mouse oocytes and preimplantation embryos by electroporation; Genesis; Vol. 32; No. 4; 269-276; 10.1002/gene.10076
• Plusa, Berenika and Piotrowska, Karolina, el al. (2002) Sperm entry position provides a surface marker for the first cleavage plane of the mouse zygote; Genesis; Vol. 32; No. 3; 193-198; 10.1002/gene.10027
• Zernicka-Goetz, Magdalena (2002) Patterning of the embryo: the first spatial decisions in the life of a mouse; Development; Vol. 129; No. 4; 815-829
• Piotrowska, Karolina and Wianny, Florence, el al. (2001) Blastomeres arising from the first cleavage division have distinguishable fates in normal mouse development; Development; Vol. 128; No. 19; 3739-3748
• Zernicka-Goetz, Magdalena and Pines, Jonathon (2001) Use of Green Fluorescent Protein in Mouse Embryos; Methods; Vol. 24; No. 1; 55-60; 10.1006/meth.2001.1157
• Piotrowska, Karolina and Zernicka-Goetz, Magdalena (2001) Role for sperm in spatial patterning of the early mouse embryo; Nature; Vol. 409; No. 6819; 517-521; 10.1038/35054069
• Ciemerych, Maria Anna and Mesnard, Daniel, el al. (2000) Animal and vegetal poles of the mouse egg predict the polarity of the embryonic axis, yet are nonessential for development; Development; Vol. 127; No. 16; 3467-3474
• Zernicka-Goetz, Magdalena (2000) Jumping the gun on mouse gene expression; Nature; Vol. 405; No. 6788; 733; 10.1038/35015787
• Grabarek, Joanna and Zernicka-Goetz, Magdalena (2000) Progression of mouse oocytes from metaphase I to metaphase II is inhibited by fusion with G2 cells; Zygote; Vol. 8; No. 2; 145-151; 10.1017/s0967199400000927
• Wianny, Florence and Zernicka-Goetz, Magdalena (2000) Specific interference with gene function by double-stranded RNA in early mouse development; Nature Cell Biology; Vol. 2; No. 2; 70-75; 10.1038/35000016
• Weber, R. J. and Pedersen, R. A., el al. (1999) Polarity of the mouse embryo is anticipated before implantation; Development; Vol. 126; No. 24; 5591-5598
• Zernicka-Goetz, Magdalena (1998) Fertile offspring derived from mammalian eggs lacking either animal or vegetal poles; Development; Vol. 125; No. 23; 4803-4808
• Wianny, Florence and Tavares, Álvaro, el al. (1998) Mouse polo-like kinase 1 associates with the acentriolar spindle poles, meiotic chromosomes and spindle midzone during oocyte maturation; Chromosoma; Vol. 107; No. 6-7; 430-439; 10.1007/s004120050327
• Zernicka-Goetz, M. and Pines, J., el al. (1997) Following cell fate in the living mouse embryo; Development; Vol. 124; No. 6; 1133-1137
• Zernicka-Goetz, M. and Verlhac, M. H., el al. (1997) Protein phosphatases control MAP kinase activation and microtubule organization during rat oocyte maturation; European journal of cell biology; Vol. 72; No. 1; 30-38
• Zernicka-Goetz, M. and Pines, J., el al. (1996) An indelible lineage marker for Xenopus using a mutated green fluorescent protein; Development; Vol. 122; No. 12; 3719-3724
• Zernicka-Goetz, Magdalena and Ciemerych, Maria A., el al. (1995) Cytostatic factor inactivation is induced by a calcium-dependent mechanism present until the second cell cycle in fertilized but not in parthenogenetically activated mouse eggs; Journal of Cell Science; Vol. 108; No. 2; 469-474
• Zernicka-Goetz, Magdalena (1994) Activation of embryonic genes during preimplantation rat development; Molecular Reproduction and Development; Vol. 38; No. 1; 30-35; 10.1002/mrd.1080380106
• Zernicka-Goetz, Magdalena and Maro, Bernard (1993) Okadaic Acid Affects Spindle Organization in Metaphase II-Arrested Rat Oocytes; Experimental Cell Research; Vol. 207; No. 1; 189-193; 10.1006/excr.1993.1179
• Zernicka-Goetz, Magdalena and Kubiak, Jacek Z., el al. (1993) Cytoskeletal organization of rat oocytes during metaphase II arrest and following abortive activation: A study by confocal laser scanning microscopy; Molecular Reproduction and Development; Vol. 35; No. 2; 165-175; 10.1002/mrd.1080350210
• Zernicka-Goetz, Magdalena and Weber, Michèle, el al. (1993) Full activation of the rat oocyte by protein synthesis inhibition requires protein phosphatase activity; International Journal of Developmental Biology; Vol. 37; No. 2; 273-277
• Zernicka-Goetz, Magdalena (1991) Spontaneous and induced activation of rat oocytes; Molecular Reproduction and Development; Vol. 28; No. 2; 169-176; 10.1002/mrd.1080280210