Stoltz, Brian

Combined from CaltechAUTHORS

Casselman, Tyler D. and Madhusudhanan, Mithun C., el al. (2025) Potassium tert-butoxide mediated stereoselective/direct Mannich reaction of α-substituted-γ-lactams with in situ generated aryl N-silyl imines; Chemical Science; Vol. 16; No. 22; 9863-9871; 10.1039/d4sc06391k
Sharp, Kimberly R. and Siddiqui, Sara Y., el al. (2025) Direct, Convergent α-Amidation of β-Keto Esters via Nickelocene Catalysis; Organic Letters; 10.1021/acs.orglett.5c01621
Moghadam, Farbod A. and Cerione, Chloe S., el al. (2025) Mo-Catalyzed Asymmetric Allylic Alkylation Enabling the Con-struction of Highly Enantioenriched 1,4-Dicarbonyl Scaffolds; 10.26434/chemrxiv-2025-41644
Moghadam, Farbod A. and Barbor, Jay P., el al. (2024) Formation of All-Carbon Quaternary Centers via Enantioselective Pd-Catalyzed α-Vinylation of γ-Lactams; Organic Letters; Vol. 26; No. 36; 7551–7554; 10.1021/acs.orglett.4c02551
Stanko, Allison M. and Ramirez, Melissa, el al. (2024) Enantioselective Nickel-Catalyzed α-Spirocyclization of Lactones; Organic Letters; Vol. 26; No. 32; 6793-6797; 10.1021/acs.orglett.4c01661
Samkian, Adrian E. and Virgil, Scott C., el al. (2024) Total Synthesis of Hypersampsone M; Journal of the American Chemical Society; 10.1021/jacs.4c07007
Ngamnithiporn, Aurapat and Welin, Eric R., el al. (2024) Evolution of a Synthetic Strategy toward the Syntheses of Bis-tetrahydroisoquinoline Alkaloids; Accounts of Chemical Research; Vol. 57; No. 13; 1870-1884; PMCID PMC11223266
Gonzalez, Kevin J. and Cerione, Chloe, el al. (2024) Strategies for the Development of Asymmetric and Non‐Directed Petasis Reactions; Chemistry – A European Journal; e202401936; 10.1002/chem.202401936
Chen, Peng-Jui and Cusumano, Alexander Q., el al. (2024) Molecular Dynamics Investigations of Dienolate [4 + 2] Reactions; Journal of the American Chemical Society; Vol. 146; No. 18; 12758-12765; PMCID PMC11082897; 10.1021/jacs.4c02681
Gross, Benjamin M. and Stoltz, Brian M. (2024) Convenient access to a strained bicyclic enone: A concise and improved formal synthesis of ineleganolide; Tetrahedron Letters; Vol. 140; 155011; 10.1016/j.tetlet.2024.155011
Hicks, Elliot F. and Inoue, Kengo, el al. (2024) Enantioselective Total Synthesis of (−)-Hunterine A Enabled by a Desymmetrization/Rearrangement Strategy; Journal of the American Chemical Society; Vol. 146; No. 7; 4340-4345; PMCID PMC10885145; 10.1021/jacs.3c13590
Xu, Yinchao and Stanko, Allison M., el al. (2024) Low Part-Per-Trillion, Humidity Resistant Detection of Nitric Oxide Using Microtoroid Optical Resonators; ACS Applied Materials & Interfaces; Vol. 16; No. 4; 5120-5128; 10.1021/acsami.3c16012
Yu, Hao and Sercel, Zachary P., el al. (2023) Total Synthesis of Aleutianamine; Journal of the American Chemical Society; Vol. 145; No. 47; 25533-25537; PMCID PMC10690800; 10.1021/jacs.3c10212
Stoltz, Brian M. (2023) Editorial for special issue in honor of Professor John Wood; Tetrahedron; Vol. 148; 133700; 10.1016/j.tet.2023.133700
Zhang, Tianyi and Nishiura, Yuji, el al. (2023) Palladium-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids to α,β-Unsaturated Lactams: Enantioselective Construction of All-Carbon Quaternary Stereocenters in Saturated Nitrogen-Containing Heterocycles; Organic Letters; Vol. 25; No. 35; 6479-6484; PMCID PMC10496148; 10.1021/acs.orglett.3c02064
Nishiura, Yuji and Gonzalez, Kevin J., el al. (2023) Enantioselective 1,3-Dipolar Cycloadditions of α-Methylene Lactams to Construct Spirocycles; Organic Letters; Vol. 25; No. 35; 6469-6473; PMCID PMC10496134; 10.1021/acs.orglett.3c01978
Cusumano, Alexander and Zhang, Tianyi, el al. (2023) Origins of Enhanced Enantioselectivity in the Pd-Catalyzed Decarboxylative Allylic Alkylation of N-Benzoyl Lactams; Catalysts; Vol. 13; No. 9; 1258; PMCID PMC10662798; 10.3390/catal13091258
Kim, Alexia N. and Ngamnithiporn, Aurapat, el al. (2023) Recent Advances in the Total Synthesis of the Tetrahydroisoquinoline Alkaloids (2002–2020); Chemical Reviews; Vol. 123; No. 15; 9447-9496; PMCID PMC10416225; 10.1021/acs.chemrev.3c00054
Barbor, Jay P. and Nair, Vaishnavi N., el al. (2023) Development of a Nickel-Catalyzed N–N Coupling for the Synthesis of Hydrazides; Journal of the American Chemical Society; Vol. 145; No. 28; 15071-15077; PMCID PMC10360072; 10.1021/jacs.3c04834
Greßies, Steffen and Süße, Lars, el al. (2023) Tandem Dearomatization/Enantioselective Allylic Alkylation of Pyridines; Journal of the American Chemical Society; Vol. 145; No. 22; 11907-11913; PMCID PMC10251512; 10.1021/jacs.3c02470
Flesch, Kaylin N. and Cusumano, Alexander Q., el al. (2023) Divergent Catalysis: Catalytic Asymmetric [4+2] Cycloaddition of Palladium Enolates; Journal of the American Chemical Society; Vol. 145; No. 20; 11301-11310; PMCID PMC10388310; 10.1021/jacs.3c02104
Hafeman, Nicholas J. and Loskot, Steven A., el al. (2023) Total synthesis of (−)-scabrolide A and (−)-yonarolide; Chemical Science; Vol. 14; No. 18; 4745-4758; PMCID PMC10173254; 10.1039/d3sc00651d
Murphy, Sara E. and Crounse, John D., el al. (2023) Accretion product formation in the self-reaction of ethene-derived hydroxy peroxy radicals; Environmental Science: Atmospheres; 10.1039/d3ea00020f
Gross, Benjamin M. and Han, Seojung, el al. (2023) A Convergent Total Synthesis of (+)-Ineleganolide; Journal of the American Chemical Society; Vol. 145; No. 14; 7763-7767; PMCID PMC10544024; 10.1021/jacs.3c02142
Gross, Benjamin M. and Han, Seo-Jung, el al. (2023) A Convergent Total Synthesis of (+)-Ineleganolide; Journal of the American Chemical Society; Vol. 145; No. 14; 7763-7767; 10.1021/jacs.3c02142
Rand, Alexander W. and Gonzalez, Kevin J., el al. (2023) Total Synthesis of Strempeliopidine and Non-Natural Stereoisomers through a Convergent Petasis Borono-Mannich Reaction; Journal of the American Chemical Society; Vol. 145; No. 13; 7278-7287; PMCID PMC10281614; 10.1021/jacs.2c13146
Gonzalez, Kevin J. and Rand, Alexander W., el al. (2023) Development of a Non‐Directed Petasis‐Type Reaction by an Aromaticity‐Disrupting Strategy; Angewandte Chemie International Edition; Vol. 62; No. 14; e202218921; PMCID PMC10033435
Reimann, Christopher E. and Kim, Kelly E., el al. (2023) What is a cross-coupling? An argument for a universal definition; Tetrahedron; Vol. 130; 133176; PMCID PMC9878734; 10.1016/j.tet.2022.133176
Hafeman, Nicholas J. and Chan, Melinda, el al. (2022) Asymmetric Total Synthesis of Havellockate; Journal of the American Chemical Society; Vol. 144; No. 44; 20232-20236; PMCID PMC9997676; 10.1021/jacs.2c09583
Zhang, Tianyi and Cusumano, Alexander Q., el al. (2022) Investigations of an Unexpected [2+2] Photocycloaddition in the Synthesis of (−)-Scabrolide A from Quantum Mechanics Calculations; Journal of Organic Chemistry; Vol. 87; No. 21; 14115-14124; 10.1021/acs.joc.2c01693
Goldstein, Elizabeth L. and Takada, Hirokazu, el al. (2022) Synthesis of enantioenriched 2,2-disubstituted pyrrolidines via sequential asymmetric allylic alkylation and ring contraction; Tetrahedron; Vol. 123; Art. No. 132940; PMCID PMC10038171; 10.1016/j.tet.2022.132940
Fulton, Tyler J. and Du, Yun E., el al. (2022) Asymmetric allylic alkylation, allylation, and related reactions; ISBN 9781119736424; Catalytic Asymmetric Synthesis, Fourth Edition; 661-704; 10.1002/9781119736424.ch17
Moghadam, Farbod A. and Hicks, Elliot F., el al. (2022) Ir-Catalyzed Asymmetric Allylic Alkylation of Dialkyl Malonates Enabling the Construction of Enantioenriched All-Carbon Quaternary Centers; Journal of the American Chemical Society; Vol. 144; No. 18; 7983-7987; 10.1021/jacs.2c02960
Kim, Alexia N. and Ngamnithiporn, Aurapat, el al. (2022) Iridium-catalyzed asymmetric trans-selective hydrogenation of 1,3-disubstituted isoquinolines; Chemical Science; Vol. 13; No. 11; 3227-3232; PMCID PMC8926345; 10.1039/d1sc06729j
Moghadam, Farbod A. and Hicks, Elliot F., el al. (2022) Ir-Catalyzed Asymmetric Allylic Alkylation of Dialkyl Malo-nates Enabling the Construction of Enantioenriched All-Carbon Quaternary Centers; 10.26434/chemrxiv-2022-n4bsw
Li, Cheng and Lohrey, Trevor D., el al. (2022) Part-per-trillion trace selective gas detection using frequency locked whispering gallery mode microtoroids; 10.26434/chemrxiv-2022-606xv
Chimiak, L. and Eiler, J., el al. (2022) Isotope effects at the origin of life: Fingerprints of the Strecker synthesis; Geochimica et Cosmochimica Acta; Vol. 321; 78-98; 10.1016/j.gca.2022.01.015
Samkian, Adrian E. and Sercel, Zachary P., el al. (2022) Some unusual transformations of a highly reactive α-bromocaranone; Tetrahedron Letters; Vol. 89; Art. No. 153496; 10.1016/j.tetlet.2021.153496
Kim, Kelly E. and Kim, Alexia N., el al. (2021) Late-Stage Diversification: A Motivating Force in Organic Synthesis; Journal of the American Chemical Society; Vol. 143; No. 41; 16890-16901; PMCID PMC9285880; 10.1021/jacs.1c08920
Lohrey, Trevor D. and Cusumano, Alexander Q., el al. (2021) Identifying the Imperative Role of Metal–Olefin Interactions in Catalytic C–O Reductive Elimination from Nickel(II); ACS Catalysis; Vol. 11; No. 16; 10208-10222; PMCID PMC8849544; 10.1021/acscatal.1c02790
Sercel, Zachary P. and Sun, Alexander W., el al. (2021) Synthesis of Enantioenriched gem-Disubstituted 4-Imidazolidinones by Palladium-Catalyzed Decarboxylative Asymmetric Allylic Alkylation; Organic Letters; Vol. 23; No. 16; 6348-6351; PMCID PMC8534816; 10.1021/acs.orglett.1c02134
Reimann, Christopher E. and Ngamnithiporn, Aurapat, el al. (2021) The Enantioselective Synthesis of Eburnamonine, Eucophylline, and 16′-epi-Leucophyllidine; Angewandte Chemie International Edition; Vol. 60; No. 33; 17957-17962; PMCID PMC8338904; 10.1002/anie.202106184
Cusumano, Alexander and Goddard, William Andrew, el al. (2021) Reductive elimination from palladium(II) via a [π2s + π2s + σ2s + σ2s] pericyclic reaction
Cusumano, Alexander Q. and Houk, K. N., el al. (2021) Synthetic strategy toward ineleganolide: A cautionary tale; Tetrahedron; Vol. 93; Art. No. 132289; PMCID PMC8294177; 10.1016/j.tet.2021.132289
Yu, Donna D. and Van Citters, Gregg, el al. (2021) Discovery of novel modulators for the PPARα (peroxisome proliferator activated receptor α): Potential therapies for nonalcoholic fatty liver disease; Bioorganic and Medicinal Chemistry; Vol. 41; Art. No. 116193; 10.1016/j.bmc.2021.116193
Han, Seo-Jung and Cavitt, Marchello A., el al. (2021) A Synthetic Strategy toward Eight-Membered Cyclic Amines by Cycloetherification and Claisen Rearrangement; Organic Letters; Vol. 23; No. 9; 3300-3303; PMCID PMC8846577; 10.1021/acs.orglett.1c00763
Süsse, Lars and Stoltz, Brian M. (2021) Enantioselective Formation of Quaternary Centers by Allylic Alkylation with First-Row Transition-Metal Catalysts; Chemical Reviews; Vol. 121; No. 7; 4084-4099; PMCID PMC8846597; 10.1021/acs.chemrev.0c01115
Zhang, Gang and Li, Shan, el al. (2021) A covalent p97/VCP ATPase inhibitor can overcome resistance to CB-5083 and NMS-873 in colorectal cancer cells; European Journal of Medicinal Chemistry; Vol. 213; Art. No. 113148; PMCID PMC7954469; 10.1016/j.ejmech.2020.113148
Li, Cheng and Lohrey, Trevor, el al. (2021) Part-per-trillion trace gas detection using frequency-locked whispering gallery mode microtoroids; ISBN 9781510642133; Integrated Optics: Devices, Materials, and Technologies XXV; Art. No. 116890B; 10.1117/12.2578032
Sardini, Stephen R. and Stoltz, Brian M. (2021) Discussion Addendum for: Preparation of (S)-tert-ButylPyOx and Palladium-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids; Organic Syntheses; Vol. 98; 117-130; PMCID PMC9558615; 10.15227/orgsyn.098.0117
Fulton, Tyler J. and Cusumano, Alexander Q., el al. (2020) Global Diastereoconvergence in the Ireland–Claisen Rearrangement of Isomeric Enolates: Synthesis of Tetrasubstituted α-Amino Acids; Journal of the American Chemical Society; Vol. 142; No. 52; 21938-21947; PMCID PMC8552564; 10.1021/jacs.0c11480
Kim, Kelly E. and Sakazaki, Yuka, el al. (2020) Synthesis of non-natural cyanthiwigin–gagunin hybrids through late-stage diversification of the cyanthiwigin natural product core; Tetrahedron; Vol. 76; No. 51; Art. No. 130755; 10.1016/j.tet.2019.130755
Kim, Alexia N. and Stoltz, Brian M. (2020) Recent Advances in Homogeneous Catalysts for the Asymmetric Hydrogenation of Heteroarenes; ACS Catalysis; Vol. 10; No. 23; 13834-13851; PMCID PMC8460131; 10.1021/acscatal.0c03958
Cusumano, Alexander Q. and Goddard, William A., III, el al. (2020) Transition Metal Catalyzed [π2s + π2s + σ2s + σ2s] Pericyclic Reaction: Woodward–Hoffmann Rules, Aromaticity, and Electron Flow; Journal of the American Chemical Society; Vol. 142; No. 45; 19033-19039; PMCID PMC8549492; 10.1021/jacs.0c09575
Ngamnithiporn, Aurapat and Iwayama, Toshihiko, el al. (2020) Enantioselective synthesis of highly oxygenated acyclic quaternary center-containing building blocks via palladium-catalyzed decarboxylative allylic alkylation of cyclic siloxyketones; Chemical Science; Vol. 11; No. 40; 11068-11071; PMCID PMC8162308; 10.1039/d0sc04383d
Fulton, Tyler J. and Chen, Anthony Y., el al. (2020) Enantioselective Total Synthesis of (–)-Myrifabral A and B; Chemical Science; Vol. 11; No. 39; 10802-10806; PMCID PMC8162428; 10.1039/d0sc01141j
Kenseth, Christopher M. and Hafeman, Nicholas J., el al. (2020) Synthesis of Carboxylic Acid and Dimer Ester Surrogates to Constrain the Abundance and Distribution of Molecular Products in α-Pinene and β-Pinene Secondary Organic Aerosol; Environmental Science and Technology; Vol. 54; No. 20; 12829-12839; 10.1021/acs.est.0c01566
Wolf, William J. and Li, Jiaming, el al. (2020) Efficient Synthesis of Geminal-Dialkyl Dienes for Olefin Metathesis Polymerization; Macromolecules; Vol. 53; No. 18; 7803-7809; PMCID PMC8297823; 10.1021/acs.macromol.0c01606
Cusumano, Alexander Q. and Stoltz, Brian M., el al. (2020) Reaction Mechanism, Origins of Enantioselectivity, and Reactivity Trends in Asymmetric Allylic Alkylation: A Comprehensive Quantum Mechanics Investigation of a C(sp³)–C(sp³) Cross-Coupling; Journal of the American Chemical Society; Vol. 142; No. 32; 13917-13933; PMCID PMC7802888; 10.1021/jacs.0c06243
Kenseth, Christopher M. and Hafeman, Nicholas J., el al. (2020) Synthesis of carboxylic acid and dimer ester surrogates to constrain the abundance and distribution of molecular products in α-pinene and β-pinene secondary organic aerosol
Inanaga, Kazato and Wollenburg, Marco, el al. (2020) Catalytic enantioselective synthesis of carbocyclic and heterocyclic spiranes via a decarboxylative aldol cyclization; Chemical Science; Vol. 11; No. 28; 7390-7395; PMCID PMC7574022; 10.1039/d0sc02366c
Duquette, Douglas C. and Cusumano, Alexander Q., el al. (2020) Probing Trends in Enantioinduction via Substrate Design: Palladium-Catalyzed Decarboxylative Allylic Alkylation of α-Enaminones; Organic Letters; Vol. 22; No. 13; 4966-4969; PMCID PMC7608880; 10.1021/acs.orglett.0c01441
Lavernhe, Rémi and Alexy, Eric J., el al. (2020) Palladium-Catalyzed Enantioselective Decarboxylative Allylic Alkylation of Acyclic α-N-Pyrrolyl/Indolyl Ketones; Organic Letters; Vol. 22; No. 11; 4272-4275; PMCID PMC7608871; 10.1021/acs.orglett.0c01303
Baek, Doohyun and Ryu, Huijeong, el al. (2020) Catalytic enantioselective synthesis of tetrasubstituted chromanones via palladium-catalyzed asymmetric conjugate arylation using chiral pyridine-dihydroisoquinoline ligands; Chemical Science; Vol. 11; No. 18; 4602-4607; PMCID PMC7574023; 10.1039/d0sc00412j
Hafeman, Nicholas J. and Loskot, Steven A., el al. (2020) The Total Synthesis of (–)-Scabrolide A; Journal of the American Chemical Society; Vol. 142; No. 19; 8585-8590; 10.1021/jacs.0c02513
Kim, Alexia N. and Ngamnithiporn, Aurapat, el al. (2020) Iridium-Catalyzed Enantioselective and Diastereoselective Hydrogenation of 1,3-Disubstituted Isoquinolines; ACS Catalysis; Vol. 10; No. 5; 3241-3248; PMCID PMC8152574; 10.1021/acscatal.0c00211
Jette, Carina I. and Tong, Z. Jaron, el al. (2020) Copper-Catalyzed Enantioselective Allylic Alkylation with a γ-Butyrolactone-Derived Silyl Ketene Acetal; Angewandte Chemie International Edition; Vol. 59; No. 5; 2033-2038; PMCID PMC7051182; 10.1002/anie.201912618
Lavernhe, Rémi and Alexy, Eric J., el al. (2020) Palladium-Catalyzed Enantioselective Decarboxylative Allylic Alkylation of Protected Benzoin-Derived Enol Carbonates; Advanced Synthesis and Catalysis; Vol. 362; No. 2; 344-347; PMCID PMC7942817; 10.1002/adsc.201901281
Park, Dongseong and Jette, Carina I., el al. (2020) Enantioselective Alkynylation of Trifluoromethyl Ketones Catalyzed by Cation-Binding Salen Nickel Complexes; Angewandte Chemie International Edition; Vol. 59; No. 2; 775-779; 10.1002/anie.201913057
Li, Jiaming and Stoltz, Brian M., el al. (2019) Enantioselective Synthesis of 15-Deoxy-Δ¹²,¹⁴-Prostaglandin J₂; Organic Letters; Vol. 21; No. 24; 10139-10142; 10.1021/acs.orglett.9b04198
Wright, Austin C. and Stoltz, Brian M. (2019) Enantioselective construction of the tricyclic core of curcusones A–D via a cross-electrophile coupling approach; Chemical Science; Vol. 10; No. 45; 10562-10565; PMCID PMC6988747; 10.1039/c9sc04127c
Wright, Austin C. and Lee, Chung Whan, el al. (2019) Progress toward the Enantioselective Synthesis of Curcusones A–D via a Divinylcyclopropane Rearrangement Strategy; Organic Letters; Vol. 21; No. 23; 9658-9662; 10.1021/acs.orglett.9b03829
Velasco-Rubio, Álvaro and Alexy, Eric J., el al. (2019) Stereospecific Overman Rearrangement of Substituted Cyclic Vinyl Bromides: Access to Fully Substituted α-Amino Ketones; Organic Letters; Vol. 21; No. 22; 8962-8965; 10.1021/acs.orglett.9b03347
Sercel, Zachary P. and Sun, Alexander W., el al. (2019) Palladium-Catalyzed Decarboxylative Asymmetric Allylic Alkylation of 1,4-Diazepan-5-ones; Organic Letters; Vol. 21; No. 22; 9158-9161; PMCID PMC8579948; 10.1021/acs.orglett.9b03530
Schuman, David P. and Liu, Wen‐Bo, el al. (2019) Transition‐Metal‐Free Catalytic C─H Bond Silylation; ISBN 9783527344536; Organosilicon Chemistry: Novel Approaches and Reactions; 213-240; 10.1002/9783527814787.ch7
Sun, Alexander W. and Lackner, Sebastian, el al. (2019) Modularity: Adding New Dimensions to Total Synthesis; Trends in Chemistry; Vol. 1; No. 7; 630-643; 10.1016/j.trechm.2019.05.008
Jones, Christopher G. and Asay, Matthew, el al. (2019) Characterization of Reactive Organometallic Species via MicroED; ACS Central Science; Vol. 5; No. 9; 1507-1513; PMCID PMC6764211; 10.1021/acscentsci.9b00403
Sun, Alexander W. and Bulterys, Philip L., el al. (2019) Incorporation of a chiral gem-disubstituted nitrogen heterocycle yields an oxazolidinone antibiotic with reduced mitochondrial toxicity; Bioorganic and Medicinal Chemistry Letters; Vol. 29; No. 18; 2686-2689; PMCID PMC6711789; 10.1016/j.bmcl.2019.07.024
Wright, Austin C. and Du, Yun Emily, el al. (2019) A Small-scale Procedure for Acid-catalyzed Ketal Formation; Journal of Organic Chemistry; Vol. 84; No. 17; 11258-11260; 10.1021/acs.joc.9b01541
Fulton, Tyler J. and Wu, Brenda, el al. (2019) Palladium-catalyzed α,β-dehydrogenation of acyclic ester equivalents promoted by a novel electron deficient phosphinooxazoline ligand; Tetrahedron; Vol. 75; No. 31; 4104-4109; PMCID PMC7119178; 10.1016/j.tet.2019.05.065
Craig, Robert A., II and Smith, Russell C., el al. (2019) Unified Enantioselective, Convergent Synthetic Approach Toward the Furanobutenolide-Derived Polycyclic Norcembranoid Diterpenes: Synthesis of a Series of Ineleganoloids by Oxidation State Manipulation of the Carbocyclic Core; Journal of Organic Chemistry; Vol. 84; No. 12; 7722-7746; 10.1021/acs.joc.9b00635
Alexy, Eric J. and Fulton, Tyler J., el al. (2019) Palladium-catalyzed enantioselective decarboxylative allylic alkylation of fully substituted N-acyl indole-derived enol carbonates; Chemical Science; Vol. 10; No. 23; 5996-6000; PMCID PMC6566452; 10.1039/c9sc01726g
Harned, Andrew M. and Stoltz, Brian M. (2019) Development of a catalytic enantioselective synthesis of the guanacastepene and heptemerone tricyclic core; Tetrahedron; Vol. 75; No. 24; 3166-3177; PMCID PMC6959853; 10.1016/j.tet.2019.02.053
Lee, Chung Whan and Taylor, Buck L. H., el al. (2019) An unexpected Ireland–Claisen rearrangement cascade during the synthesis of the tricyclic core of Curcusone C: Mechanistic elucidation by trial-and-error and automatic artificial force-induced reaction (AFIR) computations; Journal of the American Chemical Society; Vol. 141; No. 17; 6995-7004; 10.1021/jacs.9b01146
Wright, Austin C. and Stoltz, Brian M. (2019) Discussion Addendum for: The Direct Acyl-Alkylation of Arynes. Preparation of Methyl 2-(2-acetylphenyl)acetate; Organic Syntheses; Vol. 96; 80-97
Yamano, Michael M. and Knapp, Rachel R., el al. (2019) Cycloadditions of Oxacyclic Allenes and a Catalytic Asymmetric Entryway to Enantioenriched Cyclic Allenes; Angewandte Chemie International Edition; Vol. 58; No. 17; 5653-5657; PMCID PMC6456397; 10.1002/anie.201900503
Sun, Alexander W. and Stoltz, Brian M. (2019) Discussion Addendum for: Preparation of (S)-tert-ButylPHOX and (S)-2-Allyl-2-Methylcyclohexanone; ISBN 9780471264224; Organic Syntheses; 10.1002/0471264229.os095.29
Sun, Alexander and Stoltz, Brian Mark (2019) Enantioselective synthesis of gem-disubstituted N-Boc diazaheterocycles via decarboxylative asymmetric allylic alkylation
Jette, Carina I. and Geibel, Irina, el al. (2019) Palladium-Catalyzed Construction of Quaternary Stereocenters by Enantioselective Arylation of γ-Lactams with Aryl Chlorides and Bromides; Angewandte Chemie International Edition; Vol. 58; No. 13; 4297-4301; 10.1002/anie.201814475
Han, Seo-Jung and Bhat, Vikram, el al. (2019) Atroposelective Synthesis of PINAP via Dynamic Kinetic Asymmetric Transformation; Advanced Synthesis and Catalysis; Vol. 361; No. 3; 441-444; 10.1002/adsc.201801248
Sun, Alexander W. and Hess, Stephan N., el al. (2019) Enantioselective synthesis of gem-disubstituted N-Boc diazaheterocycles via decarboxylative asymmetric allylic alkylation; Chemical Science; Vol. 10; No. 3; 788-792; PMCID PMC6345351; 10.1039/c8sc03967d
Welin, Eric R. and Ngamnithiporn, Aurapat, el al. (2019) Concise total syntheses of (–)-jorunnamycin A and (–)-jorumycin enabled by asymmetric catalysis; Science; Vol. 363; No. 6424; 270-275; PMCID PMC7017906; 10.1126/science.aav3421
Praske, Eric and Otkjær, Rasmus V., el al. (2019) Intramolecular Hydrogen Shift Chemistry of Hydroperoxy-Substituted Peroxy Radicals; Journal of Physical Chemistry A; Vol. 123; No. 2; 590-600; 10.1021/acs.jpca.8b09745
Li, Jiaming and Ahmed, Tonia S., el al. (2019) Concise Syntheses of Δ^(12)-Prostaglandin J Natural Products via Stereoretentive Metathesis; Journal of the American Chemical Society; Vol. 141; No. 1; 154-158; 10.1021/jacs.8b12816
Shockley, Samantha E. and Hethcox, J. Caleb, el al. (2018) Intermolecular Stereoselective Iridium-Catalyzed Allylic Alkylation: An Evolutionary Account; Synlett; Vol. 29; No. 19; 2481-2492; PMCID PMC6870865; 10.1055/s-0037-1610217
Jones, Christopher G. and Martynowycz, Michael W., el al. (2018) The CryoEM Method MicroED as a Powerful Tool for Small Molecule Structure Determination; ACS Central Science; Vol. 4; No. 11; 1587-1592; PMCID PMC6276044; 10.1021/acscentsci.8b00760
Davies, Huw M. L. and Itami, Kenichiro, el al. (2018) New directions in natural product synthesis; Chemical Society Reviews; Vol. 47; No. 21; 7828-7829; 10.1039/c8cs90115e
Liu, Wenbin and Ren, Zhi, el al. (2018) Catalyst-Controlled Selective Functionalization of Unactivated C–H Bonds in the Presence of Electronically Activated C–H Bonds; Journal of the American Chemical Society; Vol. 140; No. 38; 12247-12255; 10.1021/jacs.8b07534
Lu, Yanhui and Goldstein, Elizabeth L., el al. (2018) Palladium-Catalyzed Enantioselective C_(sp)^3–C_(sp)^3 Cross-Coupling for the Synthesis of (Poly)fluorinated Chiral Building Blocks; Organic Letters; Vol. 20; No. 18; 5657-5660; PMCID PMC6192028; 10.1021/acs.orglett.8b02369
Wang, Xin and Zhu, Ming-Hui, el al. (2018) General and Practical Potassium Methoxide/Disilane-Mediated Dehalogenative Deuteration of (Hetero)Arylhalides; Journal of the American Chemical Society; Vol. 140; No. 35; 10970-10974; 10.1021/jacs.8b07597
Alexy, Eric J. and Zhang, Haiming, el al. (2018) Catalytic Enantioselective Synthesis of Acyclic Quaternary Centers: Palladium-Catalyzed Decarboxylative Allylic Alkylation of Fully Substituted Acyclic Enol Carbonates; Journal of the American Chemical Society; Vol. 140; No. 32; 10109-10112; PMCID PMC6103296; 10.1021/jacs.8b05560
Kenseth, Christopher M. and Huang, Yuanlong, el al. (2018) Synergistic O₃ + OH oxidation pathway to extremely low-volatility dimers revealed in β-pinene secondary organic aerosol; Proceedings of the National Academy of Sciences of the United States of America; Vol. 115; No. 33; 8301-8306; PMCID PMC6099901; 10.1073/pnas.1804671115
Al Saihati, Zainab and Haibach, Michael C., el al. (2018) Cyclic alkanes transfer dehydrogenation using homogeneous iridium pincer catalysts
Defieber, Christian and Mohr, Justin T., el al. (2018) Short Enantioselective Formal Synthesis of (–)-Platencin; Synthesis-Stuttgart; Vol. 50; No. 22; 4359-4368; PMCID PMC6498846; 10.1055/s-0037-1610437
Hartrampf, Nina and Winter, Nils, el al. (2018) Total Synthesis of the Norhasubanan Alkaloid Stephadiamine; Journal of the American Chemical Society; Vol. 140; No. 28; 8675-8680; PMCID PMC6130314; 10.1021/jacs.8b01918
Hethcox, J. Caleb and Shockley, Samantha E., el al. (2018) Enantioselective Synthesis of Vicinal All-Carbon Quaternary Centers via Iridium-Catalyzed Allylic Alkylation; Angewandte Chemie International Edition; Vol. 57; No. 28; 8664-8667; PMCID PMC6033654; 10.1002/anie.201804820
Krout, Michael R. and Henry, Christopher E., el al. (2018) Wolff/Cope Approach to the AB Ring of the Sesterterpenoid Variecolin; Journal of Organic Chemistry; Vol. 83; No. 13; 6995-7009; PMCID PMC6035096; 10.1021/acs.joc.7b02972
Pritchett, Beau P. and Stoltz, Brian M. (2018) Enantioselective palladium-catalyzed allylic alkylation reactions in the synthesis of Aspidosperma and structurally related monoterpene indole alkaloids; Natural Product Reports; Vol. 35; No. 6; 559-574; PMCID PMC6013405; 10.1039/c7np00069c
Craig, Robert A., II and Smith, Russell C., el al. (2018) Development of a Unified Enantioselective, Convergent Synthetic Approach Toward the Furanobutenolide-Derived Polycyclic Norcembranoid Diterpenes: Asymmetric Formation of the Polycyclic Norditerpenoid Carbocyclic Core by Tandem Annulation Cascade; Journal of Organic Chemistry; Vol. 83; No. 7; 3467-3485; PMCID PMC5889334; 10.1021/acs.joc.7b02825
Kim, Kelly E. and Adams, Ashley M., el al. (2018) The Cyanthiwigin Natural Product Core as a Complex Molecular Scaffold for Comparative Late-Stage C–H Functionalization Studies; Journal of Organic Chemistry; Vol. 83; No. 6; 3023-3033; 10.1021/acs.joc.7b03291
Ngamnithiporn, Aurapat and Jette, Carina I., el al. (2018) Nickel-catalyzed enantioselective allylic alkylation of lactones and lactams with unactivated allylic alcohols; Chemical Science; Vol. 2018; No. 9; 2547-2551; PMCID PMC5912103; 10.1039/c7sc05216b
Leung, Joyce and Bederman, Aaron, el al. (2018) Total synthesis of (±)-phomoidride D: A 22 year odyssey
Stoltz, Brian (2018) Award Address (ACS Award for Creative Work in Synthetic Organic Chemistry sponsored by MilliporeSigma). Complex natural products as a driving force for discovery in organic chemistry
Leung, Joyce C. and Bedermann, Aaron A., el al. (2018) Total Synthesis of (±)-Phomoidride D; Angewandte Chemie International Edition; Vol. 57; No. 7; 1991-1994; 10.1002/anie.201712369
Duquette, Douglas Charles and Jensen, Thomas, el al. (2018) Progress towards the total synthesis of hamigerans C and D: a direct approach to an elaborated 6-7-5 carbocyclic core; Journal of Antibiotics; Vol. 71; No. 2; 263-267; PMCID PMC5788718; 10.1038/ja.2017.96
Chen, Anthony Y. and Lu, Qianqian, el al. (2018) Isocanthine Synthesis via Rh(III)-Catalyzed Intramolecular C-H Functionalization; Journal of Organic Chemistry; Vol. 83; No. 1; 330-337; 10.1021/acs.joc.7b02731
Praske, Eric and Otkjær, Rasmus V., el al. (2018) Atmospheric autoxidation is increasingly important in urban and suburban North America; Proceedings of the National Academy of Sciences of the United States of America; Vol. 115; No. 1; 64-69; PMCID PMC5776813; 10.1073/pnas.1715540115
Roizen, Jennifer L. and Jones, Amanda C., el al. (2017) Model Studies to Access the [6,7,5,5]-Core of Ineleganolide Using Tandem Translactonization-Cope or Cyclopropanation-Cope Rearrangements as Key Steps; Journal of Organic Chemistry; Vol. 82; No. 24; 13051-13067; PMCID PMC5732049; 10.1021/acs.joc.7b02030
Haibach, Michael C. and Stoltz, Brian M., el al. (2017) Catalytic Reduction of Alkyl and Aryl Bromides Using Propan-2-ol; Angewandte Chemie International Edition; Vol. 56; No. 47; 15123-15126; 10.1002/anie.201708800
Alexy, Eric J. and Virgil, Scott C., el al. (2017) Enantioselective Pd-Catalyzed Decarboxylative Allylic Alkylation of Thiopyranones. Access to Acyclic, Stereogenic α-Quaternary Ketones; Organic Letters; Vol. 19; No. 19; 5007-5009; PMCID PMC5632216; 10.1021/acs.orglett.7b02354
Liniger, Marc and Liu, Yiyang, el al. (2017) Sequential Ruthenium Catalysis for Olefin Isomerization and Oxidation: Application to the Synthesis of Unusual Amino Acids; Journal of the American Chemical Society; Vol. 139; No. 39; 13944-13949; PMCID PMC5628162; 10.1021/jacs.7b08496
Pritchett, Beau P. and Donckele, Etienne J., el al. (2017) Enantioselective Catalysis Coupled with Stereodivergent Cyclization Strategies Enables Rapid Syntheses of (+)-Limaspermidine and (+)-Kopsihainanine A; Angewandte Chemie International Edition; Vol. 56; No. 41; 12624-12627; PMCID PMC5896324; 10.1002/anie.201707304
Shockley, Samantha E. and Hethcox, J. Caleb, el al. (2017) Enantioselective Synthesis of Acyclic α-Quaternary Carboxylic Acid Derivatives through Iridium-Catalyzed Allylic Alkylation; Angewandte Chemie International Edition; Vol. 56; No. 38; 11545-11548; PMCID PMC5674796; 10.1002/anie.201707015
Shockley, Samantha E. and Hethcox, J. Caleb, el al. (2017) Asymmetric Synthesis of All-Carbon Quaternary Spirocycles via a Catalytic Enantioselective Allylic Alkylation Strategy; Tetrahedron Letters; Vol. 58; No. 34; 3341-3343; PMCID PMC5578629; 10.1016/j.tetlet.2017.07.022
Loskot, Steven A. and Romney, David K., el al. (2017) Enantioselective Total Synthesis of Nigelladine A via Late-Stage C–H Oxidation Enabled by an Engineered P450 Enzyme; Journal of the American Chemical Society; Vol. 139; No. 30; 10196-10199; PMCID PMC5679227; 10.1021/jacs.7b05196
Stoltz, Brian M. (2017) Twists and turns of lactam research
Shockley, Samantha and Hethcox, Caleb, el al. (2017) Recent developments in stereoselective iridium-catalyzed allylic alkylation methodologies
Starkov, Pavel and Moore, Jared T., el al. (2017) Enantioselective Construction of Acyclic Quaternary Carbon Stereocenters: Palladium-Catalyzed Decarboxylative Allylic Alkylation of Fully-Substituted Amide Enolates; Journal of the American Chemical Society; Vol. 139; No. 28; 9615-9620; PMCID PMC5555155; 10.1021/jacs.7b04086
Craig, Robert A., II and Stoltz, Brian M. (2017) Polycyclic Furanobutenolide-Derived Cembranoid and Norcembranoid Natural Products: Biosynthetic Connections and Synthetic Efforts; Chemical Reviews; Vol. 117; No. 12; 7878-7909; PMCID PMC5497599; 10.1021/acs.chemrev.7b00083
Liu, Wen-Bo and Schuman, David P., el al. (2017) Potassium tert-Butoxide-Catalyzed Dehydrogenative C–H Silylation of Heteroaromatics: A Combined Experimental and Computational Mechanistic Study; Journal of the American Chemical Society; Vol. 139; No. 20; 6867-6879; 10.1021/jacs.6b13031
Banerjee, Shibdas and Yang, Yun-Fang, el al. (2017) Ionic and Neutral Mechanisms for C–H Bond Silylation of Aromatic Heterocycles Catalyzed by Potassium t-Butoxide; Journal of the American Chemical Society; Vol. 139; No. 20; 6880-6887; 10.1021/jacs.6b13032
Hethcox, J. Caleb and Shockley, Samantha E., el al. (2017) Enantioselective Iridium-Catalyzed Allylic Alkylation Reactions of Masked Acyl Cyanide Equivalents; Organic Letters; Vol. 19; No. 7; 1527-1529; PMCID PMC5470644; 10.1021/acs.orglett.7b00449
Stoltz, Brian M. (2017) Complex natural products as a driving force for discovery in organic chemistry
Bhat, Vikram and Welin, Eric R., el al. (2017) Advances in Stereoconvergent Catalysis from 2005 to 2015: Transition-Metal-Mediated Stereoablative Reactions, Dynamic Kinetic Resolutions, and Dynamic Kinetic Asymmetric Transformations; Chemical Reviews; Vol. 117; No. 5; 4528-4561; PMCID PMC5516946; 10.1021/acs.chemrev.6b00731
Klare, Hendrik F. T. and Goldberg, Alexander F. G., el al. (2017) Oxidative Fragmentations and Skeletal Rearrangements of Oxindole Derivatives; Organic Letters; Vol. 19; No. 5; 988-991; 10.1021/acs.orglett.6b03789
Pritchett, Beau P. and Kikuchi, Jun, el al. (2017) A Fischer Indolization Strategy toward the Total Synthesis of (–)-Goniomitine; Heterocycles; Vol. 95; No. 2; 1245-1253; PMCID PMC5502790; 10.3987/COM-16-S(S)80
Toutov, Anton A. and Betz, Kerry N., el al. (2017) Alkali metal hydroxide–catalyzed C(sp)–H bond silylation; Journal of the American Chemical Society; Vol. 139; No. 4; 1668-1674; 10.1021/jacs.6b12114
Craig, Robert A., II and Roizen, Jennifer L., el al. (2017) Enantioselective, convergent synthesis of the ineleganolide core by a tandem annulation cascade; Chemical Science; Vol. 8; No. 1; 507-514; PMCID PMC5321630; 10.1039/c6sc03347d
Hethcox, J. Caleb and Shockley, Samantha E., el al. (2016) Iridium-Catalyzed Stereoselective Allylic Alkylation Reactions with Crotyl Chloride; Angewandte Chemie International Edition; Vol. 55; No. 52; 16092-16095; PMCID PMC5207348; 10.1002/anie.201609960
Pushkarskaya, Eugenia and Wong, Brian, el al. (2016) Single-step synthesis of 3-hydroxycarbazoles by annulation of electron-rich anilines and quinones; Tetrahedron Letters; Vol. 57; No. 50; 5653-5657; 10.1016/j.tetlet.2016.11.009
Kim, Kelly E. and Stoltz, Brian M. (2016) A Second-Generation Synthesis of the Cyanthiwigin Natural Product Core; Organic Letters; Vol. 18; No. 21; 5720-5723; 10.1021/acs.orglett.6b02962
Li, Jiaming and Grubbs, Robert H., el al. (2016) Palladium-Catalyzed Aerobic Intramolecular Aminoacetoxylation of Alkenes Enabled by Catalytic Nitrate; Organic Letters; Vol. 18; No. 21; 5449-5451; PMCID PMC5512709; 10.1021/acs.orglett.6b02722
Pritchett, Beau P. and Kikuchi, Jun, el al. (2016) Enantioselective Pd-Catalyzed Allylic Alkylation Reactions of Dihydropyrido[1,2-a]indolone Substrates: Efficient Syntheses of (−)-Goniomitine, (+)-Aspidospermidine, and (−)-Quebrachamine; Angewandte Chemie International Edition; Vol. 55; No. 43; 13529-13532; PMCID PMC5207349; 10.1002/anie.201608138
Kim, Kelly E. and Li, Jiaming, el al. (2016) Catalytic Anti-Markovnikov Transformations of Hindered Terminal Alkenes Enabled by Aldehyde-Selective Wacker-Type Oxidation; Journal of the American Chemical Society; Vol. 138; No. 40; 13179-13182; 10.1021/jacs.6b08788
Krishnan, Subramanian and Chang, Alexander C., el al. (2016) Escherichia coli K1 Modulates Peroxisome Proliferator–Activated Receptor γ and Glucose Transporter 1 at the Blood-Brain Barrier in Neonatal Meningitis; Journal of Infectious Diseases; Vol. 214; No. 7; 1092-1104; PMCID PMC5021232; 10.1093/infdis/jiw306
Mohr, Justin T. and Moore, Jared T., el al. (2016) Enantioconvergent catalysis; Beilstein Journal of Organic Chemistry; Vol. 12; 2038-2045; PMCID PMC5082454; 10.3762/bjoc.12.192
Hethcox, J. Caleb and Shockley, Samantha E., el al. (2016) Iridium-Catalyzed Diastereo-, Enantio-, and Regioselective Allylic Alkylation with Prochiral Enolates; ACS Catalysis; Vol. 6; No. 9; 6207-6213; PMCID PMC5481154; 10.1021/acscatal.6b01886
Toutov, Anton A. and Liu, Wen-Bo, el al. (2016) Potassium tert-Butoxide-Catalyzed Dehydrogenative Cross-Coupling of Heteroarenes with Hydrosilanes; Organic Syntheses; Vol. 93; 263-271; 10.15227/orgsyn.093.0263
Hayashi, Masaki and Bachman, Shoshana, el al. (2016) Ni-Catalyzed Enantioselective C-Acylation of α-Substituted Lactams; Journal of the American Chemical Society; Vol. 138; No. 29; 8997-9000; PMCID PMC4963289; 10.1021/jacs.6b02120
Craig, Robert A., II and Smith, Russell C., el al. (2016) Preparation of 1,5-Dioxaspiro[5.5]undecan-3-one; Organic Syntheses; Vol. 93; 210-227; PMCID PMC5514842; 10.15227/orgsyn.093.0210
Estipona, Benzi I. and Pritchett, Beau P., el al. (2016) Catalytic enantioselective total synthesis of (+)-eucomic acid; Tetrahedron; Vol. 72; No. 26; 3707-3712; PMCID PMC4986999; 10.1016/j.tet.2016.02.059
Stoltz, Brian M. and Martin, Stephen (2016) Tetrahedron Young Investigator Award ~ 2016; Tetrahedron; Vol. 72; No. 26; iii; 10.1016/j.tet.2016.04.026
Wright, Austin C. and Haley, Christopher K., el al. (2016) Synthesis of Aryl Ketoamides via Aryne Insertion into Imides; Organic Letters; Vol. 18; No. 12; 2793-2795; 10.1021/acs.orglett.6b00994
Han, Seo-Jung and Doi, Ryohei, el al. (2016) Nickel-Catalyzed Intramolecular C−O Bond Formation: Synthesis of Cyclic Enol Ethers; Angewandte Chemie International Edition; Vol. 55; No. 26; 7437-7440; PMCID PMC4985346; 10.1002/anie.201601991
O'Connor, Nicholas R. and Wood, John L., el al. (2016) Synthetic Applications and Methodological Developments of Donor-Acceptor Cyclopropanes and Related Compounds; Israel Journal of Chemistry; Vol. 56; No. 6-7; 431-444; PMCID PMC6527366; 10.1002/ijch.201500089
Han, Seo-Jung and Stoltz, Brian M. (2016) A mild and efficient approach to enantioenriched α-hydroxyethyl α,β-unsaturated δ-lactams; Tetrahedron Letters; Vol. 57; No. 21; 2233-2235; PMCID PMC4864989; 10.1016/j.tetlet.2016.04.022
Liu, Wen-Bo and Okamoto, Noriko, el al. (2016) Enantioselective γ-Alkylation of α,β-Unsaturated Malonates and Ketoesters by a Sequential Ir-Catalyzed Asymmetric Allylic Alkylation/Cope Rearrangement; Journal of the American Chemical Society; Vol. 138; No. 16; 5234-5237; PMCID PMC5497580; 10.1021/jacs.6b02153
Bagdanoff, Jeffrey T. and Behenna, Douglas C., el al. (2016) Enantioselective Synthesis of Caprolactam and Enone Precursors to the Heterocyclic DEFG Ring System of Zoanthenol; European Journal of Organic Chemistry; Vol. 2016; No. 12; 2101-2104; PMCID PMC5225988; 10.1002/ejoc.201600223
O'Connor, Nicholas R. and Bolgar, Peter, el al. (2016) Development of a simple system for the oxidation of electron-rich diazo compounds to ketones; Tetrahedron Letters; Vol. 57; No. 8; 849-851; 10.1016/j.tetlet.2016.01.020
Liniger, Marc and VanderVelde, David G., el al. (2016) Total Synthesis and Characterization of 7-Hypoquinuclidonium Tetrafluoroborate and 7-Hypoquinuclidone BF_3 Complex; Journal of the American Chemical Society; Vol. 138; No. 3; 969-974; PMCID PMC4878439; 10.1021/jacs.5b11750
Bates, Kelvin H. and Nguyen, Tran B., el al. (2016) Production and Fate of C_4 Dihydroxycarbonyl Compounds from Isoprene Oxidation; Journal of Physical Chemistry A; Vol. 120; No. 1; 106-117; 10.1021/acs.jpca.5b10335
Su, Judith and Goldberg, Alexander F. G., el al. (2016) Label-free detection of single nanoparticles and biological molecules using microtoroid optical resonators; Light: Science and Applications; Vol. 5; No. 1; Art. No. e16001; PMCID PMC6059845; 10.1038/lsa.2016.1
Korch, Katerina M. and Loskot, Steven A., el al. (2016) Asymmetric Synthesis of Quaternary Stereocenters via Metal Enolates; ISBN 9780470682531; PATAI'S Chemistry of Functional Groups; 1-85; 10.1002/9780470682531.pat0858
Toutov, Anton A. and Liu, Wen-Bo, el al. (2015) Catalytic C–H bond silylation of aromatic heterocycles; Nature Protocols; Vol. 10; No. 12; 1897-1903; 10.1038/nprot.2015.118
Craig, Robert A., II and Loskot, Steven A., el al. (2015) Palladium-Catalyzed Enantioselective Decarboxylative Allylic Alkylation of Cyclopentanones; Organic Letters; Vol. 17; No. 21; 5160-5163; PMCID PMC4640231; 10.1021/acs.orglett.5b02376
Liu, Yiyang and Virgil, Scott C., el al. (2015) Palladium-Catalyzed Decarbonylative Dehydration for the Synthesis of α-Vinyl Carbonyl Compounds and Total Synthesis of (−)-Aspewentins A, B, and C; Angewandte Chemie International Edition; Vol. 54; No. 40; 11800-11803; PMCID PMC4686263; 10.1002/anie.201505161
Kita, Yusuke and Numajiri, Yoshitaka, el al. (2015) Construction of Tertiary Chiral Centers by Pd-catalyzed Asymmetric Allylic Alkylation of Prochiral Enolate Equivalents; Tetrahedron; Vol. 71; No. 37; 6349-6353; PMCID PMC4528676; 10.1016/j.tet.2015.05.092
Xing, Xiangyou and O'Connor, Nicholas R., el al. (2015) Palladium(II)-Catalyzed Allylic C-H Oxidation of Hindered Substrates Featuring Tunable Selectivity Over Extent of Oxidation; Angewandte Chemie International Edition; Vol. 54; No. 38; 11186-11190; 10.1002/anie.201504007
Holder, Jeffrey C. and Goodman, Emmett D., el al. (2015) Synthesis of Diverse β-Quaternary Ketones via Palladium-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids to Cyclic Enones; Tetrahedron; Vol. 71; No. 35; 5781-5792; PMCID PMC4598955; 10.1016/j.tet.2014.11.048
Shockley, Samantha E. and Holder, Jeffrey C., el al. (2015) Palladium-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids to α,β-Unsaturated Cyclic Electrophiles; Organic Process Research & Development; Vol. 19; No. 8; 974-981; PMCID PMC4896742; 10.1021/acs.oprd.5b00169
Holder, Jeffrey C. and Shockley, Samantha E., el al. (2015) Preparation of (S)-tert-ButylPyOx and Palladium-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids; Organic Syntheses; Vol. 92; 247-266; PMCID PMC6499391; 10.15227/orgsyn.092.0247
Craig, Robert A., II and Stoltz, Brian M. (2015) Synthesis and exploration of electronically modified (R)-5,5-dimethyl-(p-CF₃)₃-i-PrPHOX in palladium-catalyzed enantio- and diastereoselective allylic alkylation: a practical alternative to (R)-(p-CF₃)₃-t-BuPHOX; Tetrahedron Letters; Vol. 56; No. 32; 4670-4673; PMCID PMC4524747; 10.1016/j.tetlet.2015.06.039
Marziale, Alexander N. and Duquette, Douglas C., el al. (2015) An Efficient Protocol for the Palladium-Catalyzed Asymmetric Decarboxylative Allylic Alkylation Using Low Palladium Concentrations and a Palladium(II) Precatalyst; Advanced Synthesis and Catalysis; Vol. 357; No. 10; 2238-2245; PMCID PMC4811629; 10.1002/adsc.201500253
Bergner, Magnus and Duquette, Douglas C., el al. (2015) Exceedingly Efficient Synthesis of (±)-Grandifloracin and Acylated Analogues; Organic Letters; Vol. 17; No. 12; 3008-3010; 10.1021/acs.orglett.5b01292
Goldberg, Alexander F. G. and Craig, Robert A., II, el al. (2015) Highly functionalized donor–acceptor cyclopropanes applied toward the synthesis of the Melodinus alkaloids; Tetrahedron Letters; Vol. 56; No. 23; 2983-2990; PMCID PMC4479304; 10.1016/j.tetlet.2014.09.016
Lee, Chung Whan and Han, Seo-Jung, el al. (2015) Stereochemical evaluation of bis(phosphine) copper catalysts for the asymmetric alkylation of 3-bromooxindoles with α-arylated malonate esters; Tetrahedron; Vol. 71; No. 22; 3666-3670; PMCID PMC4429905; 10.1016/j.tet.2014.10.065
Numajiri, Yoshitaka and Jiménez-Osés, Gonzalo, el al. (2015) Enantioselective Synthesis of Dialkylated N-Heterocycles by Palladium-Catalyzed Allylic Alkylation; Organic Letters; Vol. 17; No. 5; 1082-1085; PMCID PMC6410707; 10.1021/ol503425t
Boeser, Cornelia L. and Holder, Jeffrey C., el al. (2015) Mechanistic analysis of an asymmetric palladium-catalyzed conjugate addition of arylboronic acids to β-substituted cyclic enones; Chemical Science; Vol. 6; No. 3; 1917-1922; PMCID PMC4338963; 10.1039/c4sc03337j
Li, Zining and Geng, Qian, el al. (2015) Selective syntheses of leuconolam, leuconoxine, and mersicarpine alkaloids from a common intermediate through regiocontrolled cyclizations by Staudinger reactions; Organic Chemistry Frontiers; Vol. 2; No. 3; 236-240; PMCID PMC4333676; 10.1039/C4QO00312H
Liu, Yiyang and Han, Seo-Jung, el al. (2015) Catalytic Enantioselective Construction of Quaternary Stereocenters: Assembly of Key Building Blocks for the Synthesis of Biologically Active Molecules; Accounts of Chemical Research; Vol. 48; No. 3; 740-751; PMCID PMC6410712; 10.1021/ar5004658
Toutov, Anton A. and Liu, Wen-Bo, el al. (2015) Silylation of C–H bonds in aromatic heterocycles by an Earth-abundant metal catalyst; Nature; Vol. 518; No. 7537; 80-84; 10.1038/nature14126
Numajiri, Yoshitaka and Pritchett, Beau P., el al. (2015) Enantioselective Synthesis of α‑Quaternary Mannich Adducts by Palladium-Catalyzed Allylic Alkylation: Total Synthesis of (+)-Sibirinine; Journal of the American Chemical Society; Vol. 137; No. 3; 1040-1043; PMCID PMC4311947; 10.1021/ja512124c
Korch, Katerina M. and Eidamshaus, Christian, el al. (2015) Enantioselective Synthesis of α-Secondary and α-Tertiary Piperazin-2-ones and Piperazines by Catalytic Asymmetric Allylic Alkylation; Angewandte Chemie International Edition; Vol. 54; No. 1; 179-183; PMCID PMC4285707; 10.1002/anie.201408609
Han, Seo-Jung and Vogt, Florian, el al. (2015) Evolution of a Unified, Stereodivergent Approach to the Synthesis of Communesin F and Perophoramidine; Journal of Organic Chemistry; Vol. 80; No. 1; 528-547; PMCID PMC4285143; 10.1021/jo502534g
Shockley, Samantha E. and Holder, Jeffrey C., el al. (2014) A Catalytic, Enantioselective Formal Synthesis of (+)-Dichroanone and (+)-Taiwaniaquinone H; Organic Letters; Vol. 16; No. 24; 6362-6365; PMCID PMC4275150; 10.1021/ol5031537
Han, Seo-Jung and de Melo, Gabriel Fernando, el al. (2014) A new method for the cleavage of nitrobenzyl amides and ethers; Tetrahedron Letters; Vol. 55; No. 47; 6467-6469; PMCID PMC4228375; 10.1016/j.tetlet.2014.10.006
Liu, Yiyang and Liniger, Marc, el al. (2014) Formal total syntheses of classic natural product target molecules via palladium-catalyzed enantioselective alkylation; Beilstein Journal of Organic Chemistry; Vol. 10; 2501-2512; PMCID PMC4222294; 10.3762/bjoc.10.261
Gordon, Jonny R. and Nelson, Hosea M., el al. (2014) The Total Syntheses of Basiliolide C, epi-Basiliolide C, and Protecting-Group-Free Total Syntheses of Transtaganolides C and D; Journal of Organic Chemistry; Vol. 79; No. 20; 9740-9747; 10.1021/jo501924u
Bhat, Vikram and Virgil, Scott C., el al. (2014) Asymmetric synthesis of QUINAP via dynamic kinetic resolution
Holder, Jeffrey C. and Shockley, Samantha E., el al. (2014) Development and application of a palladium-catalyzed enantioselective conjugate addition
Ma, Sandy and Reeves, Corey M., el al. (2014) Palladium-catalyzed decarboxylative allylic alkylation of diastereomeric β-ketoesters; Tetrahedron; Vol. 70; No. 27-28; 4208-4212; PMCID PMC4078409; 10.1016/j.tet.2014.03.042
Han, Seo-Jung and Vogt, Florian, el al. (2014) A Diastereodivergent Synthetic Strategy for the Syntheses of Communesin F and Perophoramidine; Organic Letters; Vol. 16; No. 12; 3316-3319; PMCID PMC4068777; 10.1021/ol5013263
Hong, Allen Y. and Stoltz, Brian M. (2014) Biosynthesis and Chemical Synthesis of Presilphiperfolanol Natural Products; Angewandte Chemie International Edition; Vol. 53; No. 21; 5248-5260; PMCID PMC4334158; 10.1002/anie.201309494
Reeves, Corey M. and Behenna, Douglas C., el al. (2014) Development of (Trimethylsilyl)ethyl Ester Protected Enolates and Applications in Palladium-Catalyzed Enantioselective Allylic Alkylation: Intermolecular Cross-Coupling of Functionalized Electrophiles; Organic Letters; Vol. 16; No. 9; 2314-2317; PMCID PMC4011571; 10.1021/ol500355z
Craig, Robert A., II and O'Connor, Nicholas R., el al. (2014) Stereoselective Lewis Acid Mediated (3+2) Cycloadditions of N-H- and N-Sulfonylaziridines with Heterocumulenes; Chemistry: a European Journal; Vol. 20; No. 16; 4806-4813; PMCID PMC4104980; 10.1002/chem.201303699
Jones, Amanda C. and May, Jeremy A., el al. (2014) Toward a Symphony of Reactivity: Cascades Involving Catalysis and Sigmatropic Rearrangements; Angewandte Chemie International Edition; Vol. 53; No. 10; 2556-2591; PMCID PMC4030764; 10.1002/anie.201302572
Bates, Kelvin H. and Crounse, John D., el al. (2014) Gas Phase Production and Loss of Isoprene Epoxydiols; Journal of Physical Chemistry A; Vol. 118; No. 7; 1237-1246; 10.1021/jp4107958
Krishnan, Subramanian and Shanmuganathan, Muthusamy V., el al. (2014) Angiotensin II Receptor Type 1—A Novel Target for Preventing Neonatal Meningitis in Mice by Escherichia coli K1; Journal of Infectious Diseases; Vol. 209; No. 3; 409-419; PMCID PMC3883175; 10.1093/infdis/jit499
Liu, Yiyang and Kim, Kelly E., el al. (2014) Palladium-Catalyzed Decarbonylative Dehydration of Fatty Acids for the Production of Linear Alpha Olefins; Advanced Synthesis and Catalysis; Vol. 356; No. 1; 130-136; PMCID PMC3998208
Stoltz, B. M. and Bennett, N. B., el al. (2014) Alkylations of Enols and Enolates; ISBN 978-0-08-097743-0; Comprehensive Organic Synthesis II; 1-55; 10.1016/B978-0-08-097742-3.00301-3
Bennett, Nathan B. and Stoltz, Brian M. (2013) A Unified Approach to the Daucane and Sphenolobane Bicyclo[5.3.0]decane Core: Enantioselective Total Syntheses of Daucene, Daucenal, Epoxydaucenal B, and 14-para-Anisoyloxydauc-4,8-diene; Chemistry: a European Journal; Vol. 19; No. 52; 17745-17750; PMCID PMC3927641; 10.1002/chem.201302353
Liu, Wen-Bo and Reeves, Corey M., el al. (2013) Enantio-, Diastereo-, and Regioselective Iridium-Catalyzed Asymmetric Allylic Alkylation of Acyclic β-Ketoesters; Journal of the American Chemical Society; Vol. 135; No. 46; 17298-17301; PMCID PMC3881553; 10.1021/ja4097829
Bhat, Vikram and Wang, Su, el al. (2013) Asymmetric Synthesis of QUINAP via Dynamic Kinetic Resolution; Journal of the American Chemical Society; Vol. 135; No. 45; 16829-16832; 10.1021/ja409383f
Holder, Jeffrey C. and Zou, Lufeng, el al. (2013) Mechanism and Enantioselectivity in Palladium-Catalyzed Conjugate Addition of Arylboronic Acids to β‑Substituted Cyclic Enones: Insights from Computation and Experiment; Journal of the American Chemical Society; Vol. 135; No. 40; 14996-15007; PMCID PMC3846424; 10.1021/ja401713g
Meyer, Michael E. and Phillips, John H., el al. (2013) Use of a palladium(II)-catalyzed oxidative kinetic resolution in synthetic efforts toward bielschowskysin; Tetrahedron; Vol. 69; No. 36; 7627-7635; PMCID PMC3728638; 10.1016/j.tet.2013.02.034
Shimizu, Hideki and Holder, Jeffrey C., el al. (2013) A scalable synthesis of the (S)-4-(tert-butyl)-2-(pyridin-2-yl)-4,5-dihydrooxazole ((S)-t-BuPyOx) ligand; Beilstein Journal of Organic Chemistry; Vol. 9; 1637-1642; PMCID PMC3778391; 10.3762/bjoc.9.187
Liu, Wen-Bo and Reeves, Corey M., el al. (2013) Construction of Vicinal Tertiary and All-Carbon Quaternary Stereocenters via Ir-Catalyzed Regio-, Diastereo-, and Enantioselective Allylic Alkylation and Applications in Sequential Pd Catalysis; Journal of the American Chemical Society; Vol. 135; No. 29; 10626-10629; PMCID PMC3756902; 10.1021/ja4052075
Haley, Christopher K. and Gilmore, Christopher D., el al. (2013) Development of a palladium-catalyzed decarboxylative cross-coupling of (2-azaaryl)carboxylates with aryl halides; Tetrahedron; Vol. 69; No. 27-28; 5732-5736; PMCID PMC3686134; 10.1016/j.tet.2013.03.085
Shibuya, Grant M. and Enquist, John A., Jr., el al. (2013) Enantioselective Synthesis of the 5–6–7 Carbocyclic Core of the Gagunin Diterpenoids; Organic Letters; Vol. 15; No. 13; 3480-3483; PMCID PMC3743267; 10.1021/ol401514s
Vieregg, Jeffrey R. and Nelson, Hosea M., el al. (2013) Selective Nucleic Acid Capture with Shielded Covalent Probes; Journal of the American Chemical Society; Vol. 135; No. 26; 9691-9699; PMCID PMC3703666; 10.1021/ja4009216
Nelson, Hosea M. and Gordon, Jonny R., el al. (2013) Total Syntheses of (-)-Transtaganolide A, (+)-Transtaganolide B, (+)-Transtaganolide C, and (-)-Transtaganolide D and Biosynthetic Implications; Angewandte Chemie International Edition; Vol. 52; No. 26; 6699-6703; PMCID PMC3825171; 10.1002/anie.201301212
Reeves, Corey M. and Eidamshaus, Christian, el al. (2013) Enantioselective Construction of α-Quaternary Cyclobutanones by Catalytic Asymmetric Allylic Alkylation; Angewandte Chemie International Edition; Vol. 52; No. 26; 6718-6721; PMCID PMC3817853; 10.1002/anie.201301815
Hong, Allen Y. and Stoltz, Brian M. (2013) The Construction of All-Carbon Quaternary Stereocenters by Use of Pd-Catalyzed Asymmetric Allylic Alkylation Reactions in Total Synthesis; European Journal of Organic Chemistry; Vol. 2013; No. 14; 2745-2759; PMCID PMC4059687; 10.1002/ejoc.201201761
Holder, Jeffrey C. and Kikushima, Kotaro, el al. (2013) Development of a palladium-catalyzed enantioselective conjugate addition of arylboronic acids to cyclic conjugate acceptors
Bennett, Nathan B. and Duquette, Douglas C., el al. (2013) Expanding Insight into Asymmetric Palladium-Catalyzed Allylic Alkylation of N-Heterocyclic Molecules and Cyclic Ketones; Chemistry: a European Journal; Vol. 19; No. 14; 4414-4418; PMCID PMC3815597; 10.1002/chem.201300030
Su, Judith and Goldberg, Alex, el al. (2013) Frequency Locked Microtoroid Optical Resonators as a Non-Invasive Tumor Biopsy Alternative; Biophysical Journal; Vol. 104; No. 2; 528A; 10.1016/j.bpj.2012.11.2924
Holder, Jeffrey C. and Marziale, Alexander N., el al. (2013) Palladium-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids to Heterocyclic Acceptors; Chemistry: a European Journal; Vol. 19; No. 1; 74-77; PMCID PMC3753812; 10.1002/chem.201203643
Caspi, Daniel D. and Zhang, Haiming, el al. (2012) Rapid and Convergent Synthesis of a 2,4'-Linked Tri-oxazole in an Approach to Poly-oxazoles; Heterocycles; Vol. 86; No. 2; 1003-1008; 10.3987/COM-12-S(N)118
Keith, John A. and Behenna, Douglas C., el al. (2012) The Reaction Mechanism of the Enantioselective Tsuji Allylation: Inner-Sphere and Outer-Sphere Pathways, Internal Rearrangements, and Asymmetric C–C Bond Formation; Journal of the American Chemical Society; Vol. 134; No. 46; 19050-19060; PMCID PMC3537505; 10.1021/ja306860n
Craig, Robert A., II and Roizen, Jennifer L., el al. (2012) Enantioselective Synthesis of a Hydroxymethyl-cis-1,3-cyclopentenediol Building Block; Organic Letters; Vol. 14; No. 22; 5716-5719; PMCID PMC3506031; 10.1021/ol3027297
Reeves, Corey M. and Stoltz, Brian M. (2012) Catalytic Enantioselective Alkylation of Prochiral Ketone Enolates; ISBN 9783527329212; Asymmetric Synthesis II: More Methods and Applications; 1-10; 10.1002/9783527652235.ch1
Goldberg, Alexander F. G. and O'Connor, Nicholas R., el al. (2012) Lewis Acid Mediated (3 + 2) Cycloadditions of Donor–Acceptor Cyclopropanes with Heterocumulenes; Organic Letters; Vol. 14; No. 20; 5314-5317; PMCID PMC3490221; 10.1021/ol302494n
Hong, Allen Y. and Stoltz, Brian M. (2012) Enantioselective Total Synthesis of the Reported Structures of (−)-9-epi-Presilphiperfolan-1-ol and (−)-Presilphiperfolan-1-ol: Structural Confirmation and Reassignment and Biosynthetic Insights; Angewandte Chemie International Edition; Vol. 51; No. 38; 9674-9678; PMCID PMC3517068; 10.1002/anie.201205276
Kim, Jimin and Stoltz, Brian M. (2012) A C–N insertion of β-lactam to benzyne: unusual formation of acridone; Tetrahedron Letters; Vol. 53; No. 37; 4994-4996; 10.1016/j.tetlet.2012.07.026
Behenna, Douglas C. and Stoltz, Brian M. (2012) Natural Products as Inspiration for Reaction Development: Catalytic Enantioselective Decarboxylative Reactions of Prochiral Enolate Equivalents; ISBN 978-3-642-34285-1; Inventing reactions; 281-314; 10.1007/3418_2012_49
Stoltz, Brian M. (2012) Novel approach to antitumor antibiotics: Using the power of benzyne in synthesis
Vieregg, Jeffrey R. and Nelson, Hosea M., el al. (2012) Sensitive and selective nucleic acid capture with shielded covalent probes
Tadross, Pamela M. and Stoltz, Brian M. (2012) A Comprehensive History of Arynes in Natural Product Total Synthesis; Chemical Reviews; Vol. 112; No. 6; 3550-3577; 10.1021/cr200478h
Behenna, Douglas C. and Liu, Yiyang, el al. (2012) Enantioselective construction of quaternary N-heterocycles by palladium-catalysed decarboxylative allylic alkylation of lactams; Nature Chemistry; Vol. 4; No. 2; 130-133; PMCID PMC3266627; 10.1038/nchem.1222
Bennett, Nathan B. and Hong, Allen Y., el al. (2012) Synthesis of enantioenriched γ-quaternary cycloheptenones using a combined allylic alkylation/Stork–Danheiser approach: preparation of mono-, bi-, and tricyclic systems; Organic and Biomolecular Chemistry; Vol. 10; No. 1; 56-59; PMCID PMC3365663; 10.1039/C1OB06189E
Hong, Allen Y. and Bennett, Nathan B., el al. (2011) Palladium-catalyzed asymmetric alkylation in the synthesis of cyclopentanoid and cycloheptanoid core structures bearing all-carbon quaternary stereocenters; Tetrahedron; Vol. 67; No. 52; 10234-10248; PMCID PMC3279929; 10.1016/j.tet.2011.10.031
Behenna, Douglas C. and Mohr, Justin T., el al. (2011) Enantioselective Decarboxylative Alkylation Reactions: Catalyst Development, Substrate Scope, and Mechanistic Studies; Chemistry: a European Journal; Vol. 17; No. 50; 14199-14223; PMCID PMC3365686; 10.1002/chem.201003383
Enquist, John A., Jr. and Virgil, Scot C., el al. (2011) Total Syntheses of Cyanthiwigins B, F, and G; Chemistry: a European Journal; Vol. 17; No. 36; 9957-9969; PMCID PMC3365662; 10.1002/chem.201100425
Goldberg, Alexander F. G. and Stoltz, Brian M. (2011) A Palladium-Catalyzed Vinylcyclopropane (3 + 2) Cycloaddition Approach to the Melodinus Alkaloids; Organic Letters; Vol. 13; No. 16; 4474-4476; PMCID PMC3155617; 10.1021/ol2017615
Tadross, Pamela M. and Bugga, Pradeep, el al. (2011) A rapid and convergent synthesis of the integrastatin core; Organic and Biomolecular Chemistry; Vol. 9; No. 15; 5354-5357; 10.1039/c1ob05725a
Day, Joshua J. and McFadden, Ryan M., el al. (2011) The Catalytic Enantioselective Total Synthesis of (+)-Liphagal; Angewandte Chemie International Edition; Vol. 50; No. 30; 6814-6818; PMCID PMC3361906; 10.1002/anie.201101842
Petersen, Kimberly S. and Stoltz, Brian M. (2011) Palladium-catalyzed, asymmetric Baeyer–Villiger oxidation of prochiral cyclobutanones with PHOX ligands; Tetrahedron; Vol. 67; No. 24; 4352-4357; 10.1016/j.tet.2011.04.046
Kikushima, Kotaro and Holder, Jeffrey C., el al. (2011) Palladium-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids to Five-, Six-, and Seven-Membered β-Substituted Cyclic Enones: Enantioselective Construction of All-Carbon Quaternary Stereocenters; Journal of the American Chemical Society; Vol. 133; No. 18; 6902-6905; PMCID PMC3087848; 10.1021/ja200664x
Allan, Kevin M. and Gilmore, Christopher D., el al. (2011) Benzannulated Bicycles by Three-Component Aryne Reactions; Angewandte Chemie International Edition; Vol. 50; No. 19; 4488-4491; 10.1002/anie.201100911
Behenna, Douglas C. and Krishnan, Shyam, el al. (2011) Confirmation of the absolute configuration of (-)-aurantioclavine; Tetrahedron Letters; Vol. 52; No. 17; 2152-2154; 10.1016/j.tetlet.2010.11.074
Nelson, Hosea M. and Murakami, Kei, el al. (2011) A General Approach to the Basiliolide/Transtaganolide Natural Products: Total Syntheses of Basiliolide B, epi-8-Basiliolide B, Transtaganolide C, and Transtaganolide D; Angewandte Chemie International Edition; Vol. 50; No. 16; 3688-3691; 10.1002/anie.201008003
Chou, Tsui-Fen and Brown, Steve J., el al. (2011) Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways; Proceedings of the National Academy of Sciences of the United States of America; Vol. 108; No. 12; 4834-4839; PMCID PMC3064330; 10.1073/pnas.1015312108
Hong, Allen Y. and Krout, Michael R., el al. (2011) Ring-Contraction Strategy for the Practical, Scalable, Catalytic Asymmetric Synthesis of Versatile γ-Quaternary Acylcyclopentenes; Angewandte Chemie International Edition; Vol. 50; No. 12; 2756-2760; PMCID PMC3365661; 10.1002/anie.201007814
Mukherjee, Herschel and McDougal, Nolan T., el al. (2011) A Catalytic, Asymmetric Formal Synthesis of (+)-Hamigeran B; Organic Letters; Vol. 13; No. 5; 825-827; PMCID PMC3045637; 10.1021/ol102669z
Stoltz, B. M. (2010) Intertwined nature of chemical synthesis and the discovery process
Stoltz, B. M. (2010) Complex natural products as a driving force for discovery in organic chemistry
McDougal, Nolan T. and Streuff, Jan, el al. (2010) Rapid synthesis of an electron-deficient t-BuPHOX ligand: cross-coupling of aryl bromides with secondary phosphine oxides; Tetrahedron Letters; Vol. 51; No. 42; 5550-5554; PMCID PMC2976555; 10.1016/j.tetlet.2010.08.039
Freeman, David B. and Holubec, Alexandra A., el al. (2010) Welwitindolinone C synthetic studies. Construction of the welwitindolinone carbon skeleton via a transannular nitrone cycloaddition; Tetrahedron; Vol. 66; No. 33; 6647-6655; PMCID PMC2924776; 10.1016/j.tet.2010.04.131
McDougal, Nolan T. and Virgil, Scott C., el al. (2010) High-Throughput Screening of the Asymmetric Decarboxylative Alkylation Reaction of Enolate-Stabilized Enol Carbonates; Synlett; Vol. 2010; No. 11; 1712-1716; PMCID PMC2976558; 10.1055/s-0030-1258094
Baumgartner, Corinne and Ma, Sandy, el al. (2010) Efforts toward rapid construction of the cortistatin A carbocyclic core via enyne-ene metathesis; Organic and Biomolecular Chemistry; Vol. 8; No. 13; 2915-2917; 10.1039/c004275g
White, David E. and Stewart, Ian C., el al. (2010) A general enantioselective route to the chamigrene natural product family; Tetrahedron; Vol. 66; No. 26; 4668-4686; PMCID PMC2925317; 10.1016/j.tet.2010.04.128
Fulmer, Gregory R. and Miller, Alexander J. M., el al. (2010) NMR Chemical Shifts of Trace Impurities: Common Laboratory Solvents, Organics, and Gases in Deuterated Solvents Relevant to the Organometallic Chemist; Organometallics; Vol. 29; No. 9; 2176-2179; 10.1021/om100106e
Tadross, Pamela M. and Virgil, Scott C., el al. (2010) Aryne Acyl-Alkylation in the General and Convergent Synthesis of Benzannulated Macrolactone Natural Products: An Enantioselective Synthesis of (−)-Curvularin; Organic Letters; Vol. 12; No. 7; 1612-1614; 10.1021/ol100335y
Tadross, Pamela M. and Gilmore, Christopher D., el al. (2010) Regioselective Reactions of Highly Substituted Arynes; Organic Letters; Vol. 12; No. 6; 1224-1227; 10.1021/ol1000796
Streuff, Jan and White, David E., el al. (2010) A palladium-catalysed enolate alkylation cascade for the formation of adjacent quaternary and tertiary stereocentres; Nature Chemistry; Vol. 2; No. 3; 192-196; PMCID PMC2917108; 10.1038/nchem.518
Allan, Kevin M. and Hong, Boram D., el al. (2009) Expedient synthesis of 3-hydroxyisoquinolines and 2-hydroxy-1,4-naphthoquinones via one-pot aryne acyl-alkylation/condensation; Organic and Biomolecular Chemistry; Vol. 7; No. 23; 4960-4964; 10.1039/b913336d
Ebner, David C. and Bagdanoff, Jeffrey T., el al. (2009) The Palladium-Catalyzed Aerobic Kinetic Resolution of Secondary Alcohols: Reaction Development, Scope, and Applications; Chemistry: a European Journal; Vol. 15; No. 47; 12978-12992; PMCID PMC2862982; 10.1002/chem.200902172
Ma, Sandy and Han, Xiaoqing, el al. (2009) Catalytic Enantioselective Stereoablative Alkylation of 3-Halooxindoles: Facile Access to Oxindoles with C3 All-Carbon Quaternary Stereocenters; Angewandte Chemie International Edition; Vol. 48; No. 1; 1-6; 10.1002/anie.200902943
Sherden, Nathaniel H. and Behenna, Douglas C., el al. (2009) Unusual Allylpalladium Carboxylate Complexes: Identification of the Resting State of Catalytic Enantioselective Decarboxylative Allylic Alkylation Reactions of Ketones; Angewandte Chemie International Edition; Vol. 48; No. 37; 6840-6843; PMCID PMC2880474; 10.1002/anie.200902575
Stockdill, Jennifer L. and Behenna, Douglas C., el al. (2009) An efficient synthesis of the carbocyclic core of zoanthenol; Tetrahedron; Vol. 65; No. 33; 6571-6575; 10.1016/j.tet.2009.05.023
Mohr, Justin T. and Hong, Allen Y., el al. (2009) Enantioselective protonation; Nature Chemistry; Vol. 1; No. 5; 359-369; PMCID PMC2860147; 10.1038/nchem.297
Stockdill, Jennifer L. and Behenna, Douglas C., el al. (2009) Unexpected decarbonylation during an acid-mediated cyclization to access the carbocyclic core of zoanthenol; Tetrahedron Letters; Vol. 50; No. 26; 3182-3184; 10.1016/j.tetlet.2009.01.121
Enquist, John A. and Stoltz, Brian M. (2009) Synthetic efforts toward cyathane diterpenoid natural products; Natural Product Reports; Vol. 26; No. 5; 661-680; PMCID PMC2683363; 10.1039/b811227b
Nelson, Hosea M. and Stoltz, Brian M. (2009) Progress toward the synthesis of the transtaganolide/basiliolide natural products: an Ireland–Claisen approach; Tetrahedron Letters; Vol. 50; No. 15; 1699-1701; 10.1016/j.tetlet.2009.01.108
Sun, Qingyu and Nelson, Hosea, el al. (2009) Side chain chemistry mediates backbone fragmentation in hydrogen deficient peptide radicals; Journal of Proteome Research; Vol. 8; No. 2; 958-966; 10.1021/pr800592t
Ebner, David C. and Tambar, Uttam K., el al. (2009) The direct acyl-alkylation of arynes. Preparation of methyl 2-(2-acetylphenyl)acetate; Organic Syntheses; Vol. 86; 161-171; 10.15227/orgsyn.086.0161
Petrova, Krastina V. and Mohr, Justin T., el al. (2009) Enantioselective Total Synthesis of (+)-Cassiol; Organic Letters; Vol. 11; No. 2; 293-295; PMCID PMC2707596; 10.1021/ol802410t
Levine, Samantha R. and Krout, Michael R., el al. (2009) Catalytic enantioselective approach to the eudesmane sesquiterpenoids: total synthesis of (+)-carissone; Organic Letters; Vol. 11; No. 2; 289-292; PMCID PMC2724392; 10.1021/ol802409h
Stoltz, Brian M. and Krout, Michael R., el al. (2009) Preparation of (S)-tert-ButylPHOX (Oxazole, 4-(1,1-dimethylethyl)-2-[2-(diphenylphosphino)phenyl]-4,5-dihydro- (4S)-); Organic Syntheses; Vol. 86; 181-193; PMCID PMC2805096; 10.15227/orgsyn.086.0181
Mohr, Justin T. and Krout, Michael R., el al. (2009) Preparation of (S)-2-Allyl-2-methylcyclohexanone (Cyclohexanone, 2-methyl-2-(2-propen-1-yl)-, (2S)-); Organic Syntheses; Vol. 86; 194-211; PMCID PMC3011275; 10.15227/orgsyn.086.0194
Allan, Kevin M. and Stoltz, Brian M. (2008) A concise total synthesis of (−)-quinocarcin via aryne annulation; Journal of the American Chemical Society; Vol. 130; No. 51; 17270-17271; 10.1021/ja808112y
Trend, Raissa M. and Stoltz, Brian M. (2008) Structural features and reactivity of (sparteine)PdCl_2: a model for selectivity in the oxidative kinetic resolution of secondary alcohols; Journal of the American Chemical Society; Vol. 130; No. 47; 15957-15966; PMCID PMC2649720; 10.1021/ja804955e
Krishnan, Shyam and Bagdanoff, Jeffrey T., el al. (2008) Pd-catalyzed enantioselective aerobic oxidation of secondary alcohols: Applications to the total synthesis of alkaloids; Journal of the American Chemical Society; Vol. 130; No. 41; 13745-13754; PMCID PMC2574996; 10.1021/ja804738b
Mohr, Justin T. and Krout, Michael R., el al. (2008) Natural products as inspiration for the development of asymmetric catalysis; Nature; Vol. 455; No. 7211; 323-332; PMCID PMC2562237; 10.1038/nature07370
Seto, Masaki and Roizen, Jennifer L., el al. (2008) Catalytic Enantioselective Alkylation of Substituted Dioxanone Enol Ethers: Ready Access to C(α)-Tetrasubstituted Hydroxyketones, Acids, and Esters; Angewandte Chemie International Edition; Vol. 47; No. 36; 6873-6876; PMCID PMC2762748; 10.1002/anie.200801424
Ebner, David C. and Trend, Raissa M., el al. (2008) Palladium-Catalyzed Enantioselective Oxidation of Chiral Secondary Alcohols: Access to Both Enantiomeric Series; Angewandte Chemie International Edition; Vol. 47; No. 34; 6367-6370; PMCID PMC2790069; 10.1002/anie.200801865
Enquist, John A., Jr. and Stoltz, Brian M. (2008) The total synthesis of (-)-cyanthiwigin F by means of double catalytic enantioselective alkylation; Nature; Vol. 453; No. 7199; 1228-1231; PMCID PMC2474750; 10.1038/nature07046
Ferreira, Eric M. and Zhang, Haiming, el al. (2008) C–H bond functionalizations with palladium(II): intramolecular oxidative annulations of arenes; Tetrahedron; Vol. 64; No. 26; 5987-6001; PMCID PMC2441596; 10.1016/j.tet.2008.01.052
Marinescu, Smaranda C. and Nishimata, Toyoki, el al. (2008) Homogeneous Pd-Catalyzed Enantioselective Decarboxylative Protonation; Organic Letters; Vol. 10; No. 6; 1039-1042; PMCID PMC2966305; 10.1021/ol702821j
Behenna, Douglas C. and Stockdill, Jennifer L., el al. (2008) The Biology and Chemistry of the Zoanthamine Alkaloids; Angewandte Chemie International Edition; Vol. 47; No. 13; 2365-2386; 10.1002/anie.200703172
Gilmore, Christopher D. and Allan, Kevin M., el al. (2008) Orthogonal Synthesis of Indolines and Isoquinolines via Aryne Annulation; Journal of the American Chemical Society; Vol. 130; No. 5; 1558-1559; 10.1021/ja0780582
White, David E. and Stewart, Ian C., el al. (2008) The Catalytic Asymmetric Total Synthesis of Elatol; Journal of the American Chemical Society; Vol. 130; No. 3; 810-811; PMCID PMC2533138; 10.1021/ja710294k
Nelson, Hosea M. and Stoltz, Brian M. (2008) Progress toward the Synthesis of the Basiliolides and Transtaganolides: An Intramolecular Pyrone Diels−Alder Entry into a Novel Class of Natural Products; Organic Letters; Vol. 10; No. 1; 25-28; 10.1021/ol702501s
Mohr, Justin T. and Stoltz, Brian M. (2007) Enantioselective Tsuji Allylations; Chemistry – An Asian Journal; Vol. 2; No. 12; 1476-1491; PMCID PMC2967289; 10.1002/asia.200700183
Mohr, Justin T. and Ebner, David C., el al. (2007) Catalytic enantioselective stereoablative reactions: an unexploited approach to enantioselective catalysis; Organic and Biomolecular Chemistry; Vol. 5; No. 22; 3571-3576; PMCID PMC2963431; 10.1039/B711159M
Keith, John A. and Behenna, Douglas C., el al. (2007) The Inner-Sphere Process in the Enantioselective Tsuji Allylation Reaction with (S)-t-Bu-phosphinooxazoline Ligands; Journal of the American Chemical Society; Vol. 129; No. 39; 11876-11877; 10.1021/ja070516j
Liu, Qi and Ferreira, Eric M., el al. (2007) Convergency and Divergency as Strategic Elements in Total Synthesis: The Total Synthesis of (−)-Drupacine and the Formal Total Synthesis of (±)-Cephalotaxine, (−)-Cephalotaxine, and (+)-Cephalotaxine; Journal of Organic Chemistry; Vol. 72; No. 19; 7352-7358; 10.1021/jo0710883
Tani, Kousuke and Behenna, Douglas C., el al. (2007) A Facile and Modular Synthesis of Phosphinooxazoline Ligands; Organic Letters; Vol. 9; No. 13; 2529-2531; 10.1021/ol070884s
Behenna, Douglas C. and Stockdill, Jennifer L., el al. (2007) Synthesis of the Carbocyclic Core of Zoanthenol: Implementation of an Unusual Acid-Catalyzed Cyclization; Angewandte Chemie International Edition; Vol. 46; No. 22; 4077-4080; 10.1002/anie.200700430
Ly, Tony and Krout, Michael, el al. (2007) Synthesis of 2-Quinuclidonium by Eliminating Water: Experimental Quantification of the High Basicity of Extremely Twisted Amides; Journal of the American Chemical Society; Vol. 129; No. 7; 1864-1865; 10.1021/ja067703m
Ferreira, Eric M. and Stoltz, Brian M. (2006) The synthesis of C-3β functionalized indoles via a hydroboration/Suzuki–Miyaura coupling sequence; Tetrahedron Letters; Vol. 47; No. 48; 8579-8582; PMCID PMC1832155; 10.1016/j.tetlet.2006.09.112
Tambar, Uttam K. and Kano, Taichi, el al. (2006) Convergent and Diastereoselective Synthesis of the Polycyclic Pyran Core of Saudin; Journal of Organic Chemistry; Vol. 71; No. 22; 8357-8364; 10.1021/jo061236+
Garg, Neil K. and Stoltz, Brian M. (2006) A unified synthetic approach to the pyrazinone dragmacidins; Chemical Communications; Vol. 2006; No. 36; 3769-3779; 10.1039/b605929e
Tambar, Uttam K. and Ebner, David C., el al. (2006) A Convergent and Enantioselective Synthesis of (+)-Amurensinine via Selective C−H and C−C Bond Insertion Reactions; Journal of the American Chemical Society; Vol. 128; No. 36; 11752-11753; PMCID PMC2529249; 10.1021/ja0651815
Mohr, Justin T. and Nishimata, Toyoki, el al. (2006) Catalytic Enantioselective Decarboxylative Protonation; Journal of the American Chemical Society; Vol. 128; No. 35; 11348-11349; 10.1021/ja063335a
McFadden, Ryan M. and Stoltz, Brian M. (2006) The Catalytic Enantioselective, Protecting Group-Free Total Synthesis of (+)-Dichroanone; Journal of the American Chemical Society; Vol. 128; No. 24; 7738-7739; 10.1021/ja061853f
Tani, Kousuke and Stoltz, Brian M. (2006) Synthesis and structural analysis of 2-quinuclidonium tetrafluoroborate; Nature; Vol. 441; No. 7094; 731-734; 10.1038/nature04842
Meyer, Michael E. and Ferreira, Eric M., el al. (2006) 2-Diazoacetoacetic acid, an efficient and convenient reagent for the synthesis of alpha-diazo-beta-ketoesters; Chemical Communications; Vol. 2006; No. 12; 1316-1318; 10.1039/b517719g
Lacenere, Christopher J. and Garg, Neil K., el al. (2006) Effects of a Modified Dye-Labeled Nucleotide Spacer Arm on Incorporation by Thermophilic DNA Polymerases; Nucleosides, Nucleotides and Nucleic Acids; Vol. 25; No. 1; 9-15; 10.1080/15257770500377714
Trend, Raissa M. and Ramtohul, Yeeman K., el al. (2005) Oxidative Cyclizations in a Nonpolar Solvent Using Molecular Oxygen and Studies on the Stereochemistry of Oxypalladation; Journal of the American Chemical Society; Vol. 127; No. 50; 17778-17788; PMCID PMC2585987; 10.1021/ja055534k
Mohr, Justin T. and Behenna, Douglas C., el al. (2005) Deracemization of Quaternary Stereocenters by Pd-Catalyzed Enantioconvergent Decarboxylative Allylation of Racemic β-Ketoesters; Angewandte Chemie International Edition; Vol. 44; No. 42; 6924-6927; 10.1002/anie.200502018
Tambar, Uttam K. and Kano, Taichi, el al. (2005) Progress toward the Total Synthesis of Saudin: Development of a Tandem Stille-Oxa-Electrocyclization Reaction; Organic Letters; Vol. 7; No. 12; 2413-2416; 10.1021/ol050705b
Caspi, Daniel D. and Garg, Neil K., el al. (2005) Heterogeneous Reductive Isomerization Reaction Using Catalytic Pd/C and H_2; Organic Letters; Vol. 7; No. 12; 2513-2516; 10.1021/ol050952f
Garg, Neil K. and Caspi, Daniel D., el al. (2005) Development of an Enantiodivergent Strategy for the Total Synthesis of (+)- and (−)-Dragmacidin F from a Single Enantiomer of Quinic Acid; Journal of the American Chemical Society; Vol. 127; No. 16; 5970-5978; 10.1021/ja050586v
Tambar, Uttam K. and Stoltz, Brian M. (2005) The Direct Acyl-Alkylation of Arynes; Journal of the American Chemical Society; Vol. 127; No. 15; 5340-5341; 10.1021/ja050859m
Garg, Neil K. and Woodroofe, Carolyn C., el al. (2005) A ligand-free solid-supported system for Sonogashira couplings: applications in nucleoside chemistry; Chemical Communications; Vol. 2005; No. 36; 4551-4553; 10.1039/b505737j
Behenna, Douglas C. and Stoltz, Brian M. (2004) The Enantioselective Tsuji Allylation; Journal of the American Chemical Society; Vol. 126; No. 46; 15044-15045; 10.1021/ja044812x
Behenna, Douglas C. and Stoltz, Brian M. (2004) The Enantioselective Tsuji Allylation; Journal of the American Chemical Society; Vol. 126; No. 46; 15044-15045; 10.1021/ja044812x
Zhang, Haiming and Ferreira, Eric M., el al. (2004) Direct Oxidative Heck Cyclizations: Intramolecular Fujiwara-Moritani Arylations for the Synthesis of Functionalized Benzofurans and Dihydrobenzofurans; Angewandte Chemie International Edition; Vol. 43; No. 45; 6144-6148; 10.1002/anie.200461294
Garg, Neil K. and Caspi, Daniel D., el al. (2004) The Total Synthesis of (+)-Dragmacidin F; Journal of the American Chemical Society; Vol. 126; No. 31; 9552-9553; 10.1021/ja046695b
Nielsen, Robert J. and Keith, Jason M., el al. (2004) A Computational Model Relating Structure and Reactivity in Enantioselective Oxidations of Secondary Alcohols by (−)-Sparteine−Pd^(II) Complexes; Journal of the American Chemical Society; Vol. 126; No. 25; 7967-7974; 10.1021/ja031911m
Trend, Raissa M. and Stoltz, Brian M. (2004) An Experimentally Derived Model for Stereoselectivity in the Aerobic Oxidative Kinetic Resolution of Secondary Alcohols by (Sparteine)PdCl_2; Journal of the American Chemical Society; Vol. 126; No. 14; 4482-4483; 10.1021/ja039551q
Su, Julius T. and Sarpong, Richmond, el al. (2004) Substituent Effects and Nearly Degenerate Transition States: Rational Design of Substrates for the Tandem Wolff−Cope Reaction; Journal of the American Chemical Society; Vol. 126; No. 1; 24-25; 10.1021/ja037716p
Bagdanoff, Jeffrey T. and Stoltz, Brian M. (2004) Palladium-Catalyzed Oxidative Kinetic Resolution with Ambient Air as the Stoichiometric Oxidation Gas; Angewandte Chemie International Edition; Vol. 43; No. 3; 353-357; 10.1002/anie.200352444
Ashley, Eric R. and Cruz, Ernest G., el al. (2003) The Total Synthesis of (−)-Lemonomycin; Journal of the American Chemical Society; Vol. 125; No. 49; 15000-15001; 10.1021/ja039223q
Sarpong, Richmond and Su, Julius T., el al. (2003) The Development of a Facile Tandem Wolff/Cope Rearrangement for the Synthesis of Fused Carbocyclic Skeletons; Journal of the American Chemical Society; Vol. 125; No. 45; 13624-13625; 10.1021/ja037587c
Ferreira, Eric M. and Stoltz, Brian M. (2003) Catalytic C−H Bond Functionalization with Palladium(II): Aerobic Oxidative Annulations of Indoles; Journal of the American Chemical Society; Vol. 125; No. 32; 9578-9579; 10.1021/ja035054y
Trend, Raissa M. and Ramtohul, Yeeman K., el al. (2003) Palladium-Catalyzed Oxidative Wacker Cyclizations in Nonpolar Organic Solvents with Molecular Oxygen: A Stepping Stone to Asymmetric Aerobic Cyclizations; Angewandte Chemie International Edition; Vol. 42; No. 25; 2892-2895; 10.1002/anie.200351196
Julian, Ryan R. and May, Jeremy A., el al. (2003) Gas-Phase Synthesis of Charged Copper and Silver Fischer Carbenes from Diazomalonates: Mechanistic and Conformational Considerations in Metal-Mediated Wolff Rearrangements; Journal of the American Chemical Society; Vol. 125; No. 15; 4478-4486; 10.1021/ja028337j
Bagdanoff, Jeffrey T. and Ferreira, Eric M., el al. (2003) Palladium-Catalyzed Enantioselective Oxidation of Alcohols: A Dramatic Rate Acceleration by Cs_2CO_3/t-BuOH; Organic Letters; Vol. 5; No. 6; 835-837; 10.1021/ol027463p
Julian, Ryan R. and May, Jeremy A., el al. (2003) Molecular Mousetraps: Gas-Phase Studies of the Covalent Coupling of Noncovalent Complexes Initiated by Reactive Carbenes Formed by Controlled Activation of Diazo Precursors; Angewandte Chemie International Edition; Vol. 42; No. 9; 1012-1015; 10.1002/anie.200390258
Garg, Neil K. and Sarpong, Richmond, el al. (2002) The First Total Synthesis of Dragmacidin D; Journal of the American Chemical Society; Vol. 124; No. 44; 13179-13184; 10.1021/ja027822b
May, Jeremy A. and Stoltz, Brian M. (2002) Non-Carbonyl-Stabilized Metallocarbenoids in Synthesis: The Development of a Tandem Rhodium-Catalyzed Bamford−Stevens/Thermal Aliphatic Claisen Rearrangement Sequence; Journal of the American Chemical Society; Vol. 124; No. 42; 12426-12427; 10.1021/ja028020j
Spessard, Sarah J. and Stoltz, Brian M. (2002) Progress toward the Synthesis of Garsubellin A and Related Phloroglucins: The Direct Diastereoselective Synthesis of the Bicyclo[3.3.1]nonane Core; Organic Letters; Vol. 4; No. 11; 1943-1946; 10.1021/ol025968+
Ferreira, Eric M. and Stoltz, Brian M. (2001) The Palladium-Catalyzed Oxidative Kinetic Resolution of Secondary Alcohols with Molecular Oxygen; Journal of the American Chemical Society; Vol. 123; No. 31; 7725-7726; 10.1021/ja015791z
Fuerst, Douglas E. and Stoltz, Brian M., el al. (2000) Synthesis of C(3) Benzofuran-Derived Bisaryl Quaternary Centers: Approaches to Diazonamide A; Organic Letters; Vol. 2; No. 22; 3521-3523; 10.1021/ol006578v
Ge, Min and Stoltz, Brian M., el al. (2000) Mechanistic Insights into the Factors Determining Exo−EndoSelectivity in the Lewis Acid-Catalyzed Diels−Alder Reaction of 1,3-Dienes with 2-Cycloalkenones; Organic Letters; Vol. 2; No. 13; 1927-1929; 10.1021/ol0060026