Simon, Melvin I.

Combined from CaltechAUTHORS

• Simon, Melvin (2016) Alfred Gilman (1941-2015); Science; Vol. 351; No. 6273; 566-566; 10.1126/science.aaf2848
• Xue, T. and Do, M. T. H., et el. (2011) Melanopsin signalling in mammalian iris and retina; Nature; Vol. 479; No. 7371; 67-73; 10.1038/nature10567
• Rebres, Robert A. and Roach, Tamara I. A., et el. (2011) Synergistic Ca^(2+) Responses by Gα_i- and Gα_q-coupled G-protein-coupled Receptors Require a Single PLCβ Isoform That Is Sensitive to Both Gβ_γ and Gα_q; Journal of Biological Chemistry; Vol. 286; No. 2; 942-951; PMCID PMC3020779; 10.1074/jbc.M110.198200
• Bao, Xiaoyan Robert and Fraser, Iain D. C., et el. (2010) Variability in G-Protein-Coupled Signaling Studied with Microfluidic Devices; Biophysical Journal; Vol. 99; No. 8; 2414-2222; 10.1016/j.bpj.2010.08.043
• Wilson, Jonathan P. and Fischer, Woodward W., et el. (2010) Geobiology of the late Paleoproterozoic Duck Creek Formation, Western Australia; Precambrian Research; Vol. 179; No. 1-4; 135-149; 10.1016/j.precamres.2010.02.019
• Imamachi, Noritaka and Park, Goon Ho, et el. (2009) TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms; Proceedings of the National Academy of Sciences of the United States of America; Vol. 106; No. 27; 11330-11335; PMCID PMC2708751; 10.1073/pnas.0905605106
• Wall, Estelle A. and Zavzavadjian, Joelle R., et el. (2009) Suppression of LPS-Induced TNF-α Production in Macrophages by cAMP Is Mediated by PKA-AKAP95-p105; Science Signaling; Vol. 2; No. 75; ra28; 10.1126/scisignal.2000202
• Hsueh, Robert C. and Natarajan, Madhusudan, et el. (2009) Deciphering Signaling Outcomes from a System of Complex Networks; Science Signaling; Vol. 2; No. 71; Art. No. ra22; PMCID PMC2711542; 10.1126/scisignal.2000054
• Roach, Tamara I. A. and Rebres, Robert A., et el. (2008) Signaling and crosstalk by C5a and UDP in macrophages selectively use PLCbeta 3 to regulate intracellular free calcium; Journal of Biological Chemistry; Vol. 283; No. 25; 17351-17361; PMCID PMC2427365; 10.1074/jbc.M800907200
• Slep, Kevin C. and Kercher, Michele A., et el. (2008) Molecular architecture of Gαo and the structural basis for RGS16-mediated deactivation; Proceedings of the National Academy of Sciences of the United States of America; Vol. 105; No. 17; 6423-6428; PMCID PMC2359805; 10.1073/pnas.0801569105
• Zhu, Xiaocui and Santat, Leah A., et el. (2007) A versatile approach to multiple gene RNA interference using microRNA-based short hairpin RNAs; BMC Molecular Biology; Vol. 8; Art. No. 98; PMCID PMC2194719; 10.1186/1471-2199-8-98
• Shi, Guixiu and Partida-Sánchz, Santiago, et el. (2007) Identification of an alternative G{alpha}q-dependent chemokine receptor signal transduction pathway in dendritic cells and granulocytes; Journal of Experimental Medicine; Vol. 204; No. 11; 2705-2718; PMCID PMC2118484; 10.1084/jem.20071267
• Pero, Ralph S. and Borchers, Michael T., et el. (2007) G{alpha}i2-mediated signaling events in the endothelium are involved in controlling leukocyte extravasation; Proceedings of the National Academy of Sciences of the United States of America; Vol. 104; No. 11; 4371-4376; PMCID PMC1838609; 10.1073/pnas.0700185104
• Zavzavadjian, Joelle R. and Coutre, Sam, et el. (2007) The Alliance for Cellular Signaling Plasmid Collection: A Flexible Resource for Protein Localization Studies and Signaling Pathway Analysis; Molecular and Cellular Proteomics; Vol. 6; No. 3; 413-424; PMCID PMC3579516; 10.1074/mcp.M600437-MCP200
• Shin, Kum-Joo and Wall, Estelle A., et el. (2006) A single lentiviral vector platform for microRNA-based conditional RNA interference and coordinated transgene expression; Proceedings of the National Academy of Sciences of the United States of America; Vol. 103; No. 37; 13759-13764; PMCID PMC1557799; 10.1073/pnas.0606179103
• Quezada, Cindy M. and Hamel, Damon J., et el. (2005) Structural and chemical requirements for histidine phosphorylation by the chemotaxis kinase CheA; Journal of Biological Chemistry; Vol. 280; No. 34; 30581-30585; 10.1074/jbc.M505316200
• Hwang, Jong-Ik and Choi, Sangdun, et el. (2005) Silencing the expression of multiple Gβ-subunits eliminates signaling mediated by all four families of G proteins; Proceedings of the National Academy of Sciences of the United States of America; Vol. 102; No. 27; 9493-9498; PMCID PMC1172260; 10.1073/pnas.0503503102
• Kovoor, Abraham and Seyffarth, Petra, et el. (2005) D₂ Dopamine Receptors Colocalize Regulator of G-Protein Signaling 9-2 (RGS9-2) via the RGS9 DEP Domain, and RGS9 Knock-Out Mice Develop Dyskinesias Associated with Dopamine Pathways; Journal of Neuroscience; Vol. 25; No. 8; 2157-2165; PMCID PMC6726050; 10.1523/jneurosci.2840-04.2005
• Park, Sang-Youn and Beel, Bryan D., et el. (2004) In different organisms, the mode of interaction between two signaling proteins is not necessarily conserved; Proceedings of the National Academy of Sciences of the United States of America; Vol. 101; No. 32; 11646-11651; PMCID PMC511033; 10.1073/pnas.0401038101
• Makino, Clint L. and Dodd, R. L., et el. (2004) Recoverin Regulates Light-dependent Phosphodiesterase Activity in Retinal Rods; Journal of General Physiology; Vol. 123; No. 6; 729-741; PMCID PMC2234569; 10.1085/jgp.200308994
• Hwang, Jong-Ik and Fraser, Iain D. C., et el. (2004) Analysis of C5a-mediated chemotaxis by lentiviral delivery of small interfering RNA; Proceedings of the National Academy of Sciences of the United States of America; Vol. 101; No. 2; 488-493; PMCID PMC327174; 10.1073/pnas.0307549100
• Bastiani, Carol A. and Gharib, Shahla, et el. (2003) Caenorhabditis elegans Gα_q Regulates Egg-Laying Behavior via a PLCβ-Independent and Serotonin-Dependent Signaling Pathway and Likely Functions Both in the Nervous System and in Muscle; Genetics; Vol. 165; No. 4; 1805-1822; PMCID PMC1462877
• Krispel, Claudia M. and Chen, Ching-Kang, et el. (2003) Novel form of adaptation in mouse retinal rods speeds recovery of phototransduction; Journal of General Physiology; Vol. 122; No. 6; 703-712; PMCID PMC2229593; 10.1085/jgp.200308938
• Marinissen, Maria Julia and Servitja, Joan-Marc, et el. (2003) Thrombin Protease-activated Receptor-1 Signals through Gq- and G13-initiated MAPK Cascades Regulating c-Jun Expression to Induce Cell Transformation; Journal of Biological Chemistry; Vol. 278; No. 47; 46814-46825; 10.1074/jbc.M305709200
• Moers, Alexandra and Nieswandt, Bernhard, et el. (2003) G_13 is an essential mediator of platelet activation in hemostasis and thrombosis; Nature Medicine; Vol. 9; No. 11; 1418-1422; 10.1038/nm943
• Yi, Tau-Mu and Kitano, Hiroaki, et el. (2003) A quantitative characterization of the yeast heterotrimeric G protein cycle; Proceedings of the National Academy of Sciences of the United States of America; Vol. 100; No. 19; 10764-10769; PMCID PMC196877; 10.1073/pnas.1834247100
• Rahman, Zia and Schwarz, Johannes, et el. (2003) RGS9 Modulates Dopamine Signaling in the Basal Ganglia; Neuron; Vol. 38; No. 6; 941-952; 10.1016/s0896-6273(03)00321-0
• Chen, Ching-Kang and Eversole-Cire, Pamela, et el. (2003) Instability of GGL domain-containing RGS proteins in mice lacking the G protein β-subunit Gβ5; Proceedings of the National Academy of Sciences of the United States of America; Vol. 100; No. 11; 6604-6609; PMCID PMC164494; 10.1073/pnas.0631825100
• Mendez, Ana and Lem, Janis, et el. (2003) Light-Dependent Translocation of Arrestin in the Absence of Rhodopsin Phosphorylation and Transducin Signaling; Journal of Neuroscience; Vol. 23; No. 8; 3124-3129; PMCID PMC6742335; 10.1523/jneurosci.23-08-03124.2003
• Gilman, Alfred G. and Simon, Melvin I., et el. (2002) Overview of the Alliance for Cellular Signaling; Nature; Vol. 420; No. 6916; 703-706; 10.1038/nature01304
• Han, Sang-Kyou and Dong, Xinzhong, et el. (2002) Orphan G protein-coupled receptors MrgA1 and MrgC11 are distinctively activated by RF-amide-related peptides through the G{alpha}q/11 pathway; Proceedings of the National Academy of Sciences of the United States of America; Vol. 99; No. 23; 14740-14745; PMCID PMC137489; 10.1073/pnas.192565799
• Miura, Masami and Watanabe, Masahiko, et el. (2002) Group I Metabotropic Glutamate Receptor Signaling via Gαq/Gα11 Secures the Induction of Long-Term Potentiation in the Hippocampal Area CA1; Journal of Neuroscience; Vol. 22; No. 19; 8379-8390; PMCID PMC6757807; 10.1523/jneurosci.22-19-08379.2002
• Hao, Wenshan and Wenzel, Andreas, et el. (2002) Evidence for two apoptotic pathways in light-induced retinal degeneration; Nature Genetics; Vol. 32; No. 2; 254-260; 10.1038/ng984
• Gu, Jennifer L. and Müller, Stefan, et el. (2002) Interaction of Gα₁₂ with Gα₁₃ and Gα_q signaling pathways; Proceedings of the National Academy of Sciences of the United States of America; Vol. 99; No. 14; 9352-9357; PMCID PMC123144; 10.1073/pnas.102291599
• Griswold, Ian J. and Zhou, Hongjun, et el. (2002) The solution structure and interactions of CheW from Thermotoga maritima; Nature Structural Biology; Vol. 9; No. 2; 121-125; 10.1038/nsb753
• Fitz-Gibbon, Sorel T. and Ladner, Heidi, et el. (2002) Genome sequence of the hyperthermophilic crenarchaeon Pyrobaculum aerophilum; Proceedings of the National Academy of Sciences of the United States of America; Vol. 99; No. 2; 984-989; PMCID PMC117417; 10.1073/pnas.241636498
• Choi, Sangdun and Hao, Wenshan, et el. (2001) Gene expression profiles of light-induced apoptosis in arrestin/rhodopsin kinase-deficient mouse retinas; Proceedings of the National Academy of Sciences of the United States of America; Vol. 98; No. 23; 13096-13101; PMCID PMC60830; 10.1073/pnas.201417498
• Dong, Xinzhong and Han, Sang-Kyou, et el. (2001) A Diverse Family of GPCRs Expressed in Specific Subsets of Nociceptive Sensory Neurons; Cell; Vol. 106; No. 5; 619-632; 10.1016/S0092-8674(01)00483-4
• Offermanns, Stefan and Negulescu, Paul, et el. (2001) Conditionally expressed Gα_(15) couples to endogenous receptors in GH_3 cells; Naunyn-Schmiedeberg's Archives of Pharmacology; Vol. 364; No. 2; 140-148; 10.1007/s002100100444
• Bilwes, Alexandrine M. and Quezada, Cindy M., et el. (2001) Nucleotide binding by the histidine kinase CheA; Nature Structural Biology; Vol. 8; No. 4; 353-360; 10.1038/86243
• Lyubarsky, A. L. and Chen, C.-K., et el. (2001) RGS9-1 is required for normal inactivation of mouse cone phototransduction; Molecular Vision; Vol. 7; No. 11; 71-78
• Venter, J. Craig and Simon, Mel (2001) The Sequence of the Human Genome; Science; Vol. 291; No. 5507; 1304-1351; 10.1126/science.1058040
• Selitrennikoff, C. P. and Alex, L., et el. (2001) COS-1, a putative two-component histidine kinase of Candida albicans, is an in vivo virulence factor; Medical Mycology; Vol. 39; No. 1; 69-74; 10.1080/mmy.39.1.69.74
• He, Wei and Lu, Lisha, et el. (2000) Modules in the photoreceptor RGS9-1•Gβ5L GTPase-accelerating protein complex control effector coupling, GTPase acceleration, protein folding, and stability; Journal of Biological Chemistry; Vol. 275; No. 47; 37093-37100; 10.1074/jbc.M006982200
• Kabarowski, Janusz H. S. and Feramisco, Jamison D., et el. (2000) Direct genetic demonstration of Gα13 coupling to the orphan G protein-coupled receptor G2A leading to RhoA-dependent actin rearrangement; Proceedings of the National Academy of Sciences of the United States of America; Vol. 97; No. 22; 12109-12114; PMCID PMC17302
• Yue, Caiping and Ku, Chun-Ying, et el. (2000) Molecular Mechanism of the Inhibition of Phospholipase C β3 by Protein Kinase C; Journal of Biological Chemistry; Vol. 275; No. 39; 30220-30225; 10.1074/jbc.M004276200
• Wieland, Thomas and Bahitjari, Nehat, et el. (2000) Polarity Exchange at the Interface of Regulators of G Protein Signaling with G Protein α-Subunits; Journal of Biological Chemistry; Vol. 275; No. 37; 28500-28506; 10.1074/jbc.M004187200
• Tsubokawa, Hiroshi and Offermanns, Stefan, et el. (2000) Calcium-Dependent Persistent Facilitation of Spike Backpropagation in the CA1 Pyramidal Neurons; Journal of Neuroscience; Vol. 20; No. 13; 4878-4884; PMCID PMC6772269; 10.1523/jneurosci.20-13-04878.2000
• Satterthwaite, Anne B. and Willis, Fiona, et el. (2000) A sensitized genetic system for the analysis of murine B lymphocyte signal transduction pathways dependent on Bruton's tyrosine kinase; Proceedings of the National Academy of Sciences of the United States of America; Vol. 97; No. 12; 6687-6692; PMCID PMC18703; 10.1073/pnas.110146697
• Haley, Jane E. and Delmas, Patrick, et el. (2000) Muscarinic Inhibition of Calcium Current and M Current in Gα_q-Deficient Mice; Journal of Neuroscience; Vol. 20; No. 11; 3973-3979; PMCID PMC6772644; 10.1523/jneurosci.20-11-03973.2000
• Hurowitz, Evan H. and Melnyk, James M., et el. (2000) Genomic Characterization of the Human Heterotrimeric G Protein α, β, and γ Subunit Genes; DNA Research; Vol. 7; No. 2; 111-120; 10.1093/dnares/7.2.111
• Yi, Tau-Mu and Huang, Yun, et el. (2000) Robust perfect adaptation in bacterial chemotaxis through integral feedback control; Proceedings of the National Academy of Sciences of the United States of America; Vol. 97; No. 9; 4649-4653; PMCID PMC18287
• Lyubarsky, A. L. and Chen, C.-K., et el. (2000) Mice Lacking G-Protein Receptor Kinase 1 Have Profoundly Slowed Recovery of Cone-Driven Retinal Responses; Journal of Neuroscience; Vol. 20; No. 6; 2209-2217; PMCID PMC6772503; 10.1523/jneurosci.20-06-02209.2000
• Kovoor, Abraham and Chen, Ching-Kang, et el. (2000) Co-expression of Gbeta 5 Enhances the Function of Two Ggamma Subunit-like Domain-containing Regulators of G Protein Signaling Proteins; Journal of Biological Chemistry; Vol. 275; No. 5; 3397-3402
• Chen, Ching-Kang and Burns, Marie E., et el. (2000) Slowed recovery of rod photoresponse in mice lacking the GTPase accelerating protein RGS9-1; Nature; Vol. 403; No. 6769; 557-560; 10.1038/35000601
• Yu, Bo and Gu, Lingjie, et el. (2000) Inhibition of Subsets of G Protein-coupled Receptors by Empty Mutants of G Protein α Subunits in Go, G11, and G16; Journal of Biological Chemistry; Vol. 275; No. 1; 71-76
• Dunham, I. and Kim, U. J., et el. (1999) The DNA sequence of human chromosome 22; Nature; Vol. 402; No. 6761; 489-495; 10.1038/990031
• Chen, Ching-Kang and Burns, Marie E., et el. (1999) Abnormal photoresponses and light-induced apoptosis in rods lacking rhodopsin kinase; Proceedings of the National Academy of Sciences of the United States of America; Vol. 96; No. 7; 3718-3722; PMCID PMC22360
• Klages, Birgit and Brandt, Ursula, et el. (1999) Activation of G(12)/G(13) results in shape change and Rho/Rho-kinase-mediated myosin light chain phosphorylation in mouse platelets; Journal of Cell Biology; Vol. 144; No. 4; 745-754; PMCID PMC2132941; 10.1083/jcb.144.4.745
• Kano, Masanobu and Hashimoto, Kouichi, et el. (1998) Phospholipase Cβ4 is specifically involved in climbing fiber synapse elimination in the developing cerebellum; Proceedings of the National Academy of Sciences of the United States of America; Vol. 95; No. 26; 15724-15729; PMCID PMC28111
• Yu, Bo and Simon, Melvin I. (1998) Interaction of the Xanthine Nucleotide Binding Goα Mutant with G Protein-coupled Receptors; Journal of Biological Chemistry; Vol. 273; No. 46; 30183-30188
• Mao, Junhao and Yuan, Huidong, et el. (1998) Specific Involvement of G Proteins in Regulation of Serum Response Factor-mediated Gene Transcription by Different Receptors; Journal of Biological Chemistry; Vol. 273; No. 42; 27118-27123; 10.1074/jbc.273.42.27118
• Satpaev, Daulet K. and Chen, Ching-Kang, et el. (1998) Autophosphorylation and ADP Regulate the Ca^(2+)-Dependent Interaction of Recoverin with Rhodopsin Kinase; Biochemistry; Vol. 37; No. 28; 10256-10262; 10.1021/bi9804986
• Alex, Lisa A. and Korch, Christopher, et el. (1998) COS1, a two-component histidine kinase that is involved in hyphal development in the opportunistic pathogen Candida albicans; Proceedings of the National Academy of Sciences of the United States of America; Vol. 95; No. 12; 7069-7073; PMCID PMC22741
• Cai, Weiwen and Jing, Junping, et el. (1998) High-resolution restriction maps of bacterial artificial chromosomes constructed by optical mapping; Proceedings of the National Academy of Sciences of the United States of America; Vol. 95; No. 7; 3390-3395; PMCID PMC19846
• Usher, Ken C. and de la Cruz, A. F., et el. (1998) Crystal structures of CheY from Thermotoga maritima do not support conventional explanations for the structural basis of enhanced thermostability; Protein Science; Vol. 7; No. 2; 403-412; PMCID PMC2143910; 10.1002/pro.5560070221
• Offermanns, Stefan and Hashimoto, Kouichi, et el. (1997) Impaired motor coordination and persistent multiple climbing fiber innervation of cerebellar Purkinje cells in mice lacking Galpha q; Proceedings of the National Academy of Sciences of the United States of America; Vol. 94; No. 25; 14089-14094; PMCID PMC28437
• Xu, Jun and Dodd, Robert L., et el. (1997) Prolonged photoresponses in transgenic mouse rods lacking arrestin; Nature; Vol. 389; No. 6650; 505-509; 10.1038/39068
• Althoefer, Henning and Eversole-Cire, Pamela, et el. (1997) Constitutively Active Galpha q and Galpha 13 Trigger Apoptosis through Different Pathways; Journal of Biological Chemistry; Vol. 1997; No. 39; 24380-24386
• Offermanns, Stefan and Toombs, Christopher F., et el. (1997) Defective platelet activation in Gα_q-deficient mice; Nature; Vol. 389; No. 6647; 183-186; 10.1038/38284
• Simon, Melvin I. (1997) Dysfunctional genomics: BACs to the rescue; Nature Biotechnology; Vol. 15; No. 9; 839; 10.1038/nbt0997-839
• Liu, Mingyao and Yu, Bo, et el. (1997) The Ca2+-dependent Binding of Calmodulin to an N-terminal Motif of the Heterotrimeric G Protein beta Subunit; Journal of Biological Chemistry; Vol. 272; No. 30; 18801-18807
• Jiang, Huiping and Kuang, Yanan, et el. (1997) Roles of phospholipase C β2 in chemoattractant-elicited responses; Proceedings of the National Academy of Sciences of the United States of America; Vol. 94; No. 15; 7971-7975; PMCID PMC21539
• Yu, Bo and Slepak, Vladlen Z., et el. (1997) Characterization of a Goα Mutant That Binds Xanthine Nucleotides; Journal of Biological Chemistry; Vol. 272; No. 29; 18015-18019
• Jiang, Meiying and Bourret, Robert B., et el. (1997) Uncoupled Phosphorylation and Activation in Bacterial Chemotaxis - The 2.3 Å structure of an aspartate to lysine mutant at position 13 of CheY; Journal of Biological Chemistry; Vol. 272; No. 18; 11850-11855; 10.1074/jbc.272.18.11850
• Wieland, Thomas and Chen, Ching-Kang, et el. (1997) The Retinal Specific Protein RGS-r Competes with the γ Subunit of cGMP Phosphodiesterase for the α Subunit of Transducin and Facilitates Signal Termination; Journal of Biological Chemistry; Vol. 272; No. 14; 8853-8856; 10.1074/jbc.272.14.8853
• Offermanns, Stefan and Mancino, Valeria, et el. (1997) Vascular System Defects and Impaired Cell Chemokinesis as a Result of Gα_(13) Deficiency; Science; Vol. 275; No. 5299; 533-536; 10.1126/science.275.5299.533
• Quick, Michael W. and Lester, Henry A., et el. (1996) Desensitization of Inositol 1,4,5-Trisphosphate/Ca2+-induced Cl- Currents by Prolonged Activation of G Proteins in Xenopus Oocytes; Journal of Biological Chemistry; Vol. 271; No. 50; 32021-32027
• Jiang, Huiping and Lyubarsky, Arkady, et el. (1996) Phospholipase C β4 is involved in modulating the visual response in mice; Proceedings of the National Academy of Sciences of the United States of America; Vol. 93; No. 25; 14598-14601; PMCID PMC26179
• Chen, Ching-Kang and Wieland, Thomas, et el. (1996) RGS-r, a retinal specific RGS protein, binds an intermediate conformation of transducin and enhances recycling; Proceedings of the National Academy of Sciences of the United States of America; Vol. 93; No. 23; 12885-12889; PMCID PMC24015
• Watson, A. John and Aragay, Anna M., et el. (1996) A Novel Form of the G Protein β Subunit Gβ5 Is Specifically Expressed in the Vertebrate Retina; Journal of Biological Chemistry; Vol. 271; No. 45; 28154-28160; 10.1074/jbc.271.45.28154
• Sanna, M. Germana and Simon, Melvin I. (1996) In vivo and in vitro characterization of Escherichia coli protein CheZ gain- and loss-of-function mutants; Journal of Bacteriology; Vol. 178; No. 21; 6275-6280
• Offmanns, Stefan and Hu, Yi-Hui, et el. (1996) Galpha 12 and Galpha 13 Are Phosphorylated during Platelet Activation; Journal of Biological Chemistry; Vol. 271; No. 42; 26044-26048
• Chen, Jeannie and Flannery, John G., et el. (1996) bcl-2 overexpression reduces apoptotic photoreceptor cell death in three different retinal degenerations; Proceedings of the National Academy of Sciences of the United States of America; Vol. 93; No. 14; 7042-7047; PMCID PMC38932; 10.1073/pnas.93.14.7042
• Liu, Mingyao and Simon, Melvin I. (1996) Regulation by cAMP-dependent protein kinease of a G-protein-mediated phospholipase C; Nature; Vol. 382; No. 6586; 83-87; 10.1038/382083a0
• Kim, Ung-Jin and Shizuya, Hiroaki, et el. (1996) A bacterial artificial chromosome-based framework contig map of human chromosome 22q; Proceedings of the National Academy of Sciences of the United States of America; Vol. 93; No. 13; 6297-6301; PMCID PMC39016; 10.1073/pnas.93.13.6297
• Stein, Jeffrey L. and Simon, Melvin I. (1996) Archaeal ubiquity; Proceedings of the National Academy of Sciences of the United States of America; Vol. 93; No. 13; 6228-6230; PMCID PMC39003; 10.1073/pnas.93.13.6228
• Jiang, Huiping and Kuang, Yanan, et el. (1996) Pertussis Toxin-sensitive Activation of Phospholipase C by the C5a and fMet-Leu-Phe Receptors; Journal of Biological Chemistry; Vol. 271; No. 23; 13430-13434
• Brundage, Lorna and Avery, Leon, et el. (1996) Mutations in a C. elegans G_qα Gene Disrupt Movement, Egg Laying, and Viability; Neuron; Vol. 16; No. 5; 999-1009; PMCID PMC4444781; 10.1016/S0896-6273(00)80123-3
• Alex, Lisa A. and Borkovich, Katherine A., et el. (1996) Hyphal development in Neurospora crassa: Involvement of a two-component histidine kinase; Proceedings of the National Academy of Sciences of the United States of America; Vol. 93; No. 8; 3416-3421; PMCID PMC39623; 10.1073/pnas.93.8.3416
• Sanna, M. Germana and Simon, Melvin I. (1996) Isolation and in vitro characterization of CheZ suppressors for the Escherichia coli chemotactic response regulator mutant CheYN23D; Journal of Biological Chemistry; Vol. 271; No. 13; 7357-7361
• Zhou, Hongjun and McEvoy, Megan M., et el. (1996) Phosphotransfer and CheY-Binding Domains of the Histidine Autokinase CheA Are Joined by a Flexible Linker; Biochemistry; Vol. 35; No. 2; 433-443; 10.1021/bi951960e
• Swanson, Ronald V. and Sanna, M. Germana, et el. (1996) Thermostable chemotaxis proteins from the hyperthermophilic bacterium Thermotoga maritima; Journal of Bacteriology; Vol. 178; No. 2; 484-489
• Li, Jiayin and Swanson, Ronald V., et el. (1995) Response Regulators CheB and CheY Exhibit Competitive Binding to the Kinase CheA; Biochemistry; Vol. 34; No. 45; 14626-14636; 10.1021/bi00045a003
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• Aragay, Anna M. and Collins, Lila R., et el. (1995) G12 Requirement for Thrombin-stimulated Gene Expression and DNA Synthesis in 1321N1 Astrocytoma Cells; Journal of Biological Chemistry; Vol. 270; No. 34; 20073-20077
• Offermanns, Stefan and Simon, Melvin I. (1995) Gα15 and Gα16 Couple a Wide Variety of Receptors to Phospholipase C; Journal of Biological Chemistry; Vol. 270; No. 25; 15175-15180; 10.1074/jbc.270.25.15175
• Kim, Ung-Jin and Shizuya, Hiroaki, et el. (1995) Selection of a sublibrary enriched for a chromosome from total human bacterial artificial chromosome library using DNA from flow sorted chromosomes as hybridization probes; Nucleic Acids Research; Vol. 23; No. 10; 1838-1839; PMCID PMC306947
• Wu, Dianqing and Jiang, Huiping, et el. (1995) Different αl-Adrenergic Receptor Sequences Required for Activating Different Gα Subunits of Gq Class of G Proteins; Journal of Biological Chemistry; Vol. 270; No. 17; 9828-9832; 10.1074/jbc.270.17.9828
• Mendel, Jane E. and Korswagen, Hendrik C., et el. (1995) Participation of the protein G_o in multiple aspects of behavior in C. elegans; Science; Vol. 267; No. 5204; 1652-1655; 10.1126/science.7886455
• Katz, Arieh and Simon, Melvin I. (1995) A segment of the C-terminal half of the G-protein .31 subunit specifies its interaction with the γ4 subunit; Proceedings of the National Academy of Sciences of the United States of America; Vol. 92; No. 6; 1998-2002; PMCID PMC42410; 10.1073/pnas.92.6.1998
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• Bowie, James U. and Pakula, Andrew A., et el. (1995) The three-dimensional structure of the aspartate receptor from Escherichia coli; Acta Crystallographica Section D: Biological Crystallography; Vol. 51; No. 2; 145-154; 10.1107/S0907444994010498
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• McGuire, P. and Bowen, T., et el. (1993) High-Altitude Time-of-Flight Search for Non-Weakly Interacting Dark Matter in Cosmic Rays
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• Aragay, Anna M. and Katz, Arieh, et el. (1992) The G alpha q and G alpha 11 proteins couple the thyrotropin-releasing hormone receptor to phospholipase C in GH3 rat pituitary cells; Journal of Biological Chemistry; Vol. 267; No. 35; 24983-24988
• Iñiguez-Lluhi, Jorge A. and Simon, Melvin I., et el. (1992) G protein beta gamma subunits synthesized in Sf9 cells. Functional characterization and the significance of prenylation of gamma; Journal of Biological Chemistry; Vol. 267; No. 32; 23409-23417
• Shizuya, Hiroaki and Birren, Bruce, et el. (1992) Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector; Proceedings of the National Academy of Sciences of the United States of America; Vol. 89; No. 18; 8794-8797; PMCID PMC50007; 10.1073/pnas.89.18.8794
• Borkovich, Katherine A. and Alex, Lisa A., et el. (1992) Attenuation of Sensory Receptor Signaling by Covalent Modification; Proceedings of the National Academy of Sciences of the United States of America; Vol. 89; No. 15; 6756-6760; PMCID PMC49582; 10.1073/pnas.89.15.6756
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• Lim, Heon Man and Simon, Melvin I. (1992) The role of negative supercoiling in Hin-mediated site-specific recombination; Journal of Biological Chemistry; Vol. 267; No. 16; 11176-11182
• Lim, Heon Man and Hughes, Kelly T., et el. (1992) The effects of symmetrical recombination site hixC on Hin recombinase function; Journal of Biological Chemistry; Vol. 267; No. 16; 11183-11190
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• Pakula, Andrew A. and Simon, Melvin I. (1992) Determination of transmembrane protein structure by disulfide cross-linking: The Escherichia coli Tar receptor; Proceedings of the National Academy of Sciences of the United States of America; Vol. 89; No. 9; 4144-4148; PMCID PMC525649; 10.1073/pnas.89.9.4144
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• Pakula, Andrew and Simon, Melvin (1992) Pivots or pistons?; Nature; Vol. 355; No. 6360; 496-497; 10.1038/355496a0
• Wu, Dianqing and Lee, Chang Ho, et el. (1992) Activation of Phospholipase C by the α Subunits of the G_q and G_(11) Proteins in Transfected Cos-7 Cells; Journal of Biological Chemistry; Vol. 267; No. 3; 1811-1817
• Wilkie, Thomas M. and Scherle, Peggy A., et el. (1991) Characterization of G-protein α subunits in the Gq class: expression in murine tissues and in stromal and hematopoietic cell lines; Proceedings of the National Academy of Sciences of the United States of America; Vol. 88; No. 22; 10049-10053; PMCID PMC52865; 10.1073/pnas.88.22.10049
• Strathmann, Michael P. and Simon, Melvin I. (1991) Gα12 and Gα13 subunits define a fourth class of G protein α subunits; Proceedings of the National Academy of Sciences of the United States of America; Vol. 88; No. 13; 5582-5586; PMCID PMC51921; 10.1073/pnas.88.13.5582
• Amatruda, Thomas T., III and Steele, David A., et el. (1991) Gα16, a G Protein α Subunit Specifically Expressed in Hematopoietic Cells; Proceedings of the National Academy of Sciences of the United States of America; Vol. 88; No. 13; 5587-5591; PMCID PMC51922; 10.1073/pnas.88.13.5587
• Bourret, Robert B. and Borkovich, Katherine A., et el. (1991) Signal Transduction Pathways Involving Protein Phosphorylation in Prokaryotes; Annual Review of Biochemistry; Vol. 60; 401-441; 10.1146/annurev.biochem.60.1.401
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• Strathmann, Michael and Hamilton, Bruce A., et el. (1991) Transposon-facilitated DNA sequencing; Proceedings of the National Academy of Sciences of the United States of America; Vol. 88; No. 4; 1247-1250; PMCID PMC50994; 10.1073/pnas.88.4.1247
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• Thomas, Kelwyn and Del Mazo, Jesus, et el. (1990) Developmental regulation of expression of the lactate dehydrogenase (LDH) multigene family during mouse spermatogenesis; Development; Vol. 109; No. 2; 483-493
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• Simon, Melvin I. (1990) Activation and Densensitization in Bacterial Chemotaxis; ISBN 9783642836206; Activation and Desensitization of Transducing Pathways; 3-21; 10.1007/978-3-642-83618-3_1
• Robinson, Murray O. and McCarrey, John R., et el. (1989) Transcriptional regulatory regions of testis-specific PGK2 defined in transgenic mice; Proceedings of the National Academy of Sciences of the United States of America; Vol. 86; No. 21; 8437-8441; PMCID PMC298297; 10.1073/pnas.86.21.8437
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• Borkovich, Katherine A. and Kaplan, Nachum, et el. (1989) Transmembrane Signal Transduction in Bacterial Chemotaxis Involves Ligand-Dependent Activation of Phosphate Group Transfer; Proceedings of the National Academy of Sciences of the United States of America; Vol. 86; No. 4; 1208-1212; PMCID PMC286655; 10.1073/pnas.86.4.1208
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• Kaplan, Nachum and Simon, Melvin I. (1988) Purification and characterization of the wild-type and mutant carboxy-terminal domains of the Escherichia coli Tar chemoreceptor; Journal of Bacteriology; Vol. 170; No. 11; 5134-5140
• Blatt, Cila and Eversole-Cire, Pamela, et el. (1988) Chromosomal localization of genes encoding guanine nucleotide-binding protein subunits in mouse and human; Proceedings of the National Academy of Sciences of the United States of America; Vol. 85; No. 20; 7642-7646; PMCID PMC282248; 10.1073/pnas.85.20.7642
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• Oosawa, Kenji and Mutoh, Norihiro, et el. (1988) Cloning of the C-terminal cytoplasmic fragment of the tar protein and effects of the fragment on chemotaxis of Escherichia coli; Journal of Bacteriology; Vol. 170; No. 6; 2521-2526
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• Fong, Henry K. W. and Yoshimoto, Kenneth K., et el. (1988) Identification of a GTP-binding protein alpha subunit that lacks an apparent ADP-ribosylation site for pertussis toxin; Proceedings of the National Academy of Sciences of the United States of America; Vol. 85; No. 9; 3066-3070; PMCID PMC280144; 10.1073/pnas.85.9.3066
• Amatruda, Thomas T., III and Gautam, Narasimha, et el. (1988) The 35- and 36-kDa β Subunits of GTP-binding Regulatory Proteins Are Products of Separate Genes; Journal of Biological Chemistry; Vol. 263; No. 11; 5008-5011
• Bogenmann, E. and Lochrie, M. A., et el. (1988) Cone cell-specific genes expressed in retinoblastoma; Science; Vol. 240; No. 4848; 76-78; 10.1126/science.2451289
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• Fong, Henry K. W. and Amatruda, Thomas T., III, et el. (1987) Distinct forms of the ß subunit of GTP-binding regulatory proteins identified by molecular cloning; Proceedings of the National Academy of Sciences of the United States of America; Vol. 84; No. 11; 3792-3796; PMCID PMC304962; 10.1073/pnas.84.11.3792
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• Sparkes, Robert S. and Simon, Melvin, et el. (1986) Assignment of the Human and Mouse Prion Protein Genes to Homologous Chromosomes; Proceedings of the National Academy of Sciences of the United States of America; Vol. 83; No. 19; 7358-7362; PMCID PMC386716; 10.1073/pnas.83.19.7358
• Oosawa, Kenji and Simon, Melvin (1986) Analysis of Mutations in the Transmembrane Region of the Aspartate Chemoreceptor in Escherichia coli; Proceedings of the National Academy of Sciences of the United States of America; Vol. 83; No. 18; 6930-6934; PMCID PMC386624; 10.1073/pnas.83.18.6930
• Mutoh, Norihiro and Oosawa, Kenji, et el. (1986) Characterization of Escherichia coli chemotaxis receptor mutants with null phenotypes; Journal of Bacteriology; Vol. 167; No. 3; 992-998
• Fong, Henry K. W. and Hurley, James B., et el. (1986) Repetitive Segmental Structure of the Transducin β Subunit: Homology with the CDC4 Gene and Identification of Related mRNAs; Proceedings of the National Academy of Sciences of the United States of America; Vol. 93; No. 7; 2162-2166; PMCID PMC323251; 10.1073/pnas.83.7.2162
• Mutoh, Norihiro and Simon, Melvin I. (1986) Nucleotide sequence corresponding to five chemotaxis genes in Escherichia coli; Journal of Bacteriology; Vol. 165; No. 1; 161-166
• Donovan, James J. and Simon, Melvin I., et el. (1985) Requirements for the Translocation of Diphtheria Toxin Fragment A across Lipid Membranes; Journal of Biological Chemistry; Vol. 260; No. 15; 8817-8823
• Kant, Jeffrey A. and Fornace, Albert J., Jr., et el. (1985) Evolution and Organization of the Fibrinogen Locus on Chromosome 4: Gene Duplication Accompanied by Transposition and Inversion; Proceedings of the National Academy of Sciences of the United States of America; Vol. 82; No. 8; 2344-2348; PMCID PMC397554; 10.1073/pnas.82.8.2344
• Lochrie, Michael A. and Hurley, James B., et el. (1985) Sequence of the Alpha Subunit of Photoreceptor G Protein: Homologies between Transducin, ras, and Elongation Factors; Science; Vol. 228; No. 4695; 96-99; 10.1126/science.3856323
• Cohn, Daniel H. and Mileham, Alan J., et el. (1985) Nucleotide sequence of the luxA gene of Vibrio harveyi and the complete amino acid sequence of the alpha subunit of bacterial luciferase; Journal of Biological Chemistry; Vol. 260; No. 10; 6139-6146
• Krikos, Alexandra and Conley, M. Patricia, et el. (1985) Chimeric chemosensory transducers of Escherichia coli; Proceedings of the National Academy of Sciences of the United States of America; Vol. 82; No. 5; 1326-1330; PMCID PMC397253; 10.1073/pnas.82.5.1326
• Williams, J. C. and Steiner, L. A., et el. (1984) Primary structure of the L subunit of the reaction center from Rhodopseudomonas sphaeroides; Proceedings of the National Academy of Sciences of the United States of America; Vol. 81; No. 23; 7303-7307; PMCID PMC392134; 10.1073/pnas.81.23.7303
• Hurley, James B. and Simon, Melvin I., et el. (1984) Homologies between Signal Transducing G Proteins and ras Gene Products; Science; Vol. 226; No. 4676; 860-862; 10.1126/science.6436980
• Hurley, James B. and Fong, Henry K. W., et el. (1984) Isolation and Characterization of a cDNA Clone for the gamma Subunit of Bovine Retinal Transducin; Proceedings of the National Academy of Sciences of the United States of America; Vol. 81; No. 22; 6948-6952; PMCID PMC392053; 10.1073/pnas.81.22.6948
• Bruist, Michael F. and Simon, Melvin I. (1984) Phase variation and the Hin protein: in vivo activity measurements, protein overproduction, and purification; Journal of Bacteriology; Vol. 159; No. 1; 71-79
• Blatt, Cila and Harper, Mary E., et el. (1984) Chromosomal mapping of murine c-fes and c-src genes; Molecular and Cellular Biology; Vol. 4; No. 5; 978-981; PMCID PMC368852; 10.1128/MCB.4.5.978
• Silverman, M. and Belas, R., et el. (1984) Genetic control of bacterial adhesion; ISBN 9783642701399; Microbial Adhesion and Aggregation; 95-107; 10.1007/978-3-642-70137-5_8
• Williams, J. C. and Steiner, L. A., et el. (1983) Primary structure of the M subunit of the reaction center from Rhodopseudomonas sphaeroides; Proceedings of the National Academy of Sciences of the United States of America; Vol. 80; No. 21; 6505-6509; PMCID PMC390381; 10.1073/pnas.80.21.6505
• Blatt, Cila and Mileham, Karen, et el. (1983) Chromosomal mapping of the mink cell focus-inducing and xenotropic env gene family in the mouse; Proceedings of the National Academy of Sciences of the United States of America; Vol. 80; No. 20; 6298-6302; PMCID PMC394284; 10.1073/pnas.80.20.6298
• Cohn, Daniel H. and Ogden, Richard C., et el. (1983) Cloning of the Vibrio harveyi luciferase genes: use of a synthetic oligonucleotide probe; Proceedings of the National Academy of Sciences of the United States of America; Vol. 80; No. 1; 120-123; PMCID PMC393321; 10.1073/pnas.80.1.120
• Donovan, James J. and Simon, Melvin I., et el. (1981) Diphtheria toxin forms transmembrane channels in planar lipid bilayers; Proceedings of the National Academy of Sciences of the United States of America; Vol. 78; No. 1; 172-176; 10.1073/pnas.78.1.172
• Draper, Rockford K. and Simon, Melvin I. (1980) The entry of diphtheria toxin into the mammalian cell cytoplasm: evidence for lysosomal involvement; Journal of Cell Biology; Vol. 87; No. 3; 849-854; PMCID PMC2110783; 10.1083/jcb.87.3.849
• Boyd, Alan and Simon, Melvin I. (1980) Multiple electrophoretic forms of methyl-accepting chemotaxis proteins generated by stimulus-elicited methylation in Escherichia coli; Journal of Bacteriology; Vol. 143; No. 2; 809-815; PMCID PMC294367
• Draper, Rockford K. and Chin, Daniel, et el. (1978) Diphtheria toxin has the properties of a lectin; Proceedings of the National Academy of Sciences of the United States of America; Vol. 75; No. 1; 261-265; 10.1073/pnas.75.1.261
• Ridgway, H. F. and Silverman, M., et el. (1977) Localization of proteins controlling motility and chemotaxis in Escherichia coli; Journal of Bacteriology; Vol. 132; No. 2; 657-665
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• Silverman, Michael and Simon, Melvin (1974) Assembly of Hybrid Flagellar Filaments; Journal of Bacteriology; Vol. 118; No. 2; 750-752; PMCID PMC246810
• Silverman, Michael and Simon, Melvin (1974) Positioning Flagellar Genes in Escherichia coli by Deletion Analysis; Journal of Bacteriology; Vol. 117; No. 1; 73-79; PMCID PMC246526
• Silverman, Michael and Simon, Melvin (1973) Genetic Analysis of Bacteriophage Mu-Induced Flagellar Mutants in Escherichia coli; Journal of Bacteriology; Vol. 116; No. 1; 114-122; PMCID PMC246398
• Silverman, M. and Simon, M. (1973) Genetic Analysis of Flagellar Mutants in Escherichia coli; Journal of Bacteriology; Vol. 113; No. 1; 105-113; PMCID PMC251608
• Silverman, Michael R. and Simon, Melvin I. (1972) Flagellar Assembly Mutants in Escherichia coli; Journal of Bacteriology; Vol. 112; No. 2; 986-993; PMCID PMC251511
• Van Alstyne, D. and Simon, M. I. (1971) Division Mutants of Bacillus subtilis: Isolation and PBS1 Transduction of Division-Specific Markers; Journal of Bacteriology; Vol. 108; No. 3; 1366-1379
• Dimmitt, K. and Simon, M. I. (1971) Purification and Partial Characterization of Bacillus subtilis Flagellar Hooks; Journal of Bacteriology; Vol. 108; No. 1; 282-286
• Emerson, Suzanne U. and Simon, Melvin I. (1971) Variation in the Primary Structure of Bacillus subtilis Flagellins; Journal of Bacteriology; Vol. 106; No. 3; 949-954; PMCID PMC248734
• Dimmitt, K. and Simon, M. (1971) Purification and Thermal Stability of Intact Bacillus subtilis Flagella; Journal of Bacteriology; Vol. 105; No. 1; 369-375
• Van Alstyne, D. and Grant, G. F., et el. (1969) Synthesis of Bacterial Flagella: Chromosomal Synchrony and Flagella Synthesis; Journal of Bacteriology; Vol. 100; No. 1; 283-287
• Grant, Geoffrey F. and Simon, Melvin I. (1969) Synthesis of Bacterial Flagella. II. PBSl Transduction of Flagella-specific Markers in Bacillus subtilis; Journal of Bacteriology; Vol. 99; No. 1; 116-124; PMCID PMC249975
• Dimmitt, K. and Bradford, S., et el. (1968) Synthesis of Bacterial Flagella. I. Requirement for Protein and Ribonucleic Acid Synthesis During Flagellar Regeneration in Bacillus subtilis; Journal of Bacteriology; Vol. 95; No. 3; 801-810; PMCID PMC252096
• Grant, Geoffrey F. and Simon, Melvin (1968) Use of Radioactive Antibodies for Characterizing Antigens and Application to the Study of Flagella Synthesis; Journal of Bacteriology; Vol. 95; No. 1; 81-86; PMCID PMC251974