@article{https://authors.library.caltech.edu/records/m8tmr-4v534, title = "T-cell commitment inheritance—an agent-based multi-scale model", journal = "npj Systems Biology and Applications", url = "https://authors.library.caltech.edu/records/m8tmr-4v534", id = "record", issn = "2056-7189", doi = "10.1038/s41540-024-00368-y", volume = "10", pmcid = "PMC11024127" } @article{https://authors.library.caltech.edu/records/5tqf9-jve59, title = "Multiplex, Quantitative, High-Resolution Imaging of Protein:Protein Complexes via Hybridization Chain Reaction", journal = "ACS Chemical Biology", url = "https://authors.library.caltech.edu/records/5tqf9-jve59", id = "record", issn = "1554-8929", doi = "10.1021/acschembio.3c00431", volume = "19", pmcid = "PMC10877569" } @article{https://authors.library.caltech.edu/records/ndath-7vx81, title = "Distinct use of super-enhancer elements controls cell type–specific CD25 transcription and function", journal = "Science Immunology", url = "https://authors.library.caltech.edu/records/ndath-7vx81", id = "record", issn = "2470-9468", doi = "10.1126/sciimmunol.adi8217", volume = "8" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20230227-88449200.51, title = "Speed and navigation control of thymocyte development by the fetal T-cell gene regulatory network", journal = "Immunological Reviews", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230227-88449200.51", id = "record", issn = "0105-2896", doi = "10.1111/imr.13190" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20230612-735539000.37, title = "Cold Spring Harbor Laboratory 2022: emerging insights and viewpoints in immunology", journal = "Trends in Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230612-735539000.37", id = "record", issn = "1471-4906", doi = "10.1016/j.it.2023.02.003", volume = "44" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20230308-468102500.15, title = "Multi-modular structure of the gene regulatory network for specification and commitment of murine T cells", journal = "Frontiers in Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230308-468102500.15", id = "record", issn = "1664-3224", doi = "10.3389/fimmu.2023.1108368", volume = "14", pmcid = "PMC9928580" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20230725-705920000.10, title = "Transcription factors specifically control change", journal = "Genes and Development", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230725-705920000.10", id = "record", issn = "0890-9369", doi = "10.1101/gad.350308.122", volume = "36", pmcid = "PMC9851400" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20221104-613497100.22, title = "The Heart of the Machine: Construction of T Cell Identity, Made Accessible", journal = "Journal of Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20221104-613497100.22", id = "record", issn = "0022-1767", doi = "10.4049/jimmunol.2200264", volume = "209" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220523-164956000, title = "Single-cell deletion analyses show control of pro–T cell developmental speed and pathways by Tcf7, Spi1, Gata3, Bcl11a, Erg, and Bcl11b", journal = "Science Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220523-164956000", id = "record", issn = "2470-9468", doi = "10.1126/sciimmunol.abm1920", volume = "7", pmcid = "PMC9273332" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20210408-133238795, title = "Logic and lineage impacts on functional transcription factor deployment for T-cell fate commitment", journal = "Biophysical Journal", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210408-133238795", id = "record", issn = "0006-3495", doi = "10.1016/j.bpj.2021.04.002", volume = "120" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20210701-152448019, title = "Stage-specific action of Runx1 and GATA3 controls silencing of PU.1 expression in mouse pro-T cells", journal = "Journal of Experimental Medicine", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210701-152448019", id = "record", issn = "0022-1007", doi = "10.1084/jem.20202648", volume = "218", pmcid = "PMC8241539" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20210517-094542881, title = "Epigenetic Dynamics in the Function of T-Lineage Regulatory Factor Bcl11b", journal = "Frontiers in Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210517-094542881", id = "record", issn = "1664-3224", doi = "10.3389/fimmu.2021.669498", volume = "12", pmcid = "PMC8079813" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20210115-132721294, title = "Single-cell insights into the hematopoietic generation of T-lymphocyte precursors in mouse and human", journal = "Experimental Hematology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210115-132721294", id = "record", issn = "0301-472X", doi = "10.1016/j.exphem.2020.12.005", volume = "95", pmcid = "PMC8018899" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200805-161737516, title = "How transcription factors drive choice of the T cell fate", journal = "Nature Reviews. Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200805-161737516", id = "record", issn = "1474-1733", doi = "10.1038/s41577-020-00426-6", volume = "21" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20210122-095153963, title = "Runx1 and Runx3 drive progenitor to T-lineage transcriptome conversion in mouse T cell commitment via dynamic genomic site switching", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210122-095153963", id = "record", issn = "0027-8424", doi = "10.1073/pnas.2019655118", volume = "118", pmcid = "PMC7848575" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20190612-072821066, title = "Multi-scale Dynamical Modeling of T Cell Development from an Early Thymic Progenitor State to Lineage Commitment", journal = "Cell Reports", url = "https://resolver.caltech.edu/CaltechAUTHORS:20190612-072821066", id = "record", issn = "2211-1247", doi = "10.1016/j.celrep.2020.108622", volume = "34", pmcid = "PMC7943435" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201202-080830637, title = "How haematopoiesis research became a fertile ground for regulatory network biology as pioneered by Eric Davidson", journal = "Current Opinion in Hematology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201202-080830637", id = "record", issn = "1065-6251", doi = "10.1097/moh.0000000000000628", volume = "28", pmcid = "PMC7755131" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200805-124144469, title = "Notch2 complements Notch1 to mediate inductive signaling that initiates early T cell development", journal = "Journal of Cell Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200805-124144469", id = "record", issn = "0021-9525", doi = "10.1083/jcb.202005093", volume = "219", pmcid = "PMC7659720" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200909-142850654, title = "Illuminating the core of adaptive immunity—how the regulatory genome controls Rag chromatin dynamics", journal = "Science Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200909-142850654", id = "record", issn = "2470-9468", doi = "10.1126/sciimmunol.abd6427", volume = "5" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20210122-150022129, title = "Functional dissection of the Il2ra superenhancer reveals developmentally regulated and cell type specific elements", journal = "Journal of Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210122-150022129", id = "record", issn = "0022-1767", volume = "204" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20191105-110746748, title = "Cell type–specific actions of Bcl11b in early T-lineage and group 2 innate lymphoid cells", journal = "Journal of Experimental Medicine", url = "https://resolver.caltech.edu/CaltechAUTHORS:20191105-110746748", id = "record", issn = "0022-1007", doi = "10.1084/jem.20190972", volume = "217", pmcid = "PMC7037248" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20191106-101546926, title = "Dynamic control of the T-cell specification gene regulatory network", journal = "Current Opinion in Systems Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20191106-101546926", id = "record", issn = "2452-3100", doi = "10.1016/j.coisb.2019.10.012", volume = "18", pmcid = "PMC7015151" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20191120-074200678, title = "Building a Human Thymus: A Pointillist View", journal = "Immunity", url = "https://resolver.caltech.edu/CaltechAUTHORS:20191120-074200678", id = "record", issn = "1074-7613", doi = "10.1016/j.immuni.2019.10.003", volume = "51" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20191016-124948167, title = "Single-Cell Analysis Reveals Regulatory Gene Expression Dynamics Leading to Lineage Commitment in Early T Cell Development", journal = "Cell Systems", url = "https://resolver.caltech.edu/CaltechAUTHORS:20191016-124948167", id = "record", issn = "2405-4712", doi = "10.1016/j.cels.2019.09.008", volume = "9", pmcid = "PMC6932747" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20191003-090223396, title = "Advice from Cell Press Reviewers", journal = "Cell", url = "https://resolver.caltech.edu/CaltechAUTHORS:20191003-090223396", id = "record", issn = "0092-8674", doi = "10.1016/j.cell.2019.08.044", volume = "179" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20190926-101246969, title = "Programming for T-lymphocyte fates: modularity and mechanisms", journal = "Genes and Development", url = "https://resolver.caltech.edu/CaltechAUTHORS:20190926-101246969", id = "record", issn = "0890-9369", doi = "10.1101/gad.327163.119", volume = "33", pmcid = "PMC6719619" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20190513-081636901, title = "Causal Gene Regulatory Network Modeling and Genomics: Second-Generation Challenges", journal = "Journal of Computational Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20190513-081636901", id = "record", issn = "1066-5277", doi = "10.1089/cmb.2019.0098", volume = "26", pmcid = "PMC6661971" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20190122-161308867, title = "Encounters across networks: Windows into principles of genomic regulation", journal = "Marine Genomics", url = "https://resolver.caltech.edu/CaltechAUTHORS:20190122-161308867", id = "record", issn = "1874-7787", doi = "10.1016/j.margen.2019.01.003", volume = "44", pmcid = "PMC6431589" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20190228-144651277, title = "Mechanisms of Action of Hematopoietic Transcription Factor PU.1 in Initiation of T-Cell Development", journal = "Frontiers in Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20190228-144651277", id = "record", issn = "1664-3224", doi = "10.3389/fimmu.2019.00228", volume = "10", pmcid = "PMC6391351" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20180830-074139017, title = "Bcl11b sets pro-T cell fate by site-specific cofactor recruitment and by repressing Id2 and Zbtb16", journal = "Nature Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180830-074139017", id = "record", issn = "1529-2908", doi = "10.1038/s41590-018-0238-4", volume = "19", pmcid = "PMC6240390" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20181030-143317624, title = "A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment", journal = "eLife", url = "https://resolver.caltech.edu/CaltechAUTHORS:20181030-143317624", id = "record", issn = "2050-084X", doi = "10.7554/eLife.37851", volume = "7", pmcid = "PMC6245732" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20180910-100610307, title = "Pioneering, chromatin remodeling, and epigenetic constraint in early T-cell gene regulation by SPI1 (PU.1)", journal = "Genome Research", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180910-100610307", id = "record", issn = "1088-9051", doi = "10.1101/gr.231423.117", volume = "28", pmcid = "PMC6169891" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20180621-101905456, title = "Transcription Factor PU.1 Represses and Activates Gene Expression in Early T Cells by Redirecting Partner Transcription Factor Binding", journal = "Immunity", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180621-101905456", id = "record", issn = "1074-7613", doi = "10.1016/j.immuni.2018.04.024", volume = "48", pmcid = "PMC6063530" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170724-090958953, title = "Cytokines, Transcription Factors, and the Initiation of T-Cell Development", journal = "Cold Spring Harbor Perspectives in Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170724-090958953", id = "record", issn = "1943-0264", doi = "10.1101/cshperspect.a028621", volume = "10", pmcid = "PMC5876153" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20180223-094424466, title = "Transformation of Accessible Chromatin and 3D Nucleome Underlies Lineage Commitment of Early T Cells", journal = "Immunity", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180223-094424466", id = "record", issn = "1074-7613", doi = "10.1016/j.immuni.2018.01.013", volume = "48", pmcid = "PMC5847274" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20171017-101505757, title = "Fitting structure to function in gene regulatory networks", journal = "History and Philosophy of the Life Sciences", url = "https://resolver.caltech.edu/CaltechAUTHORS:20171017-101505757", id = "record", issn = "0391-9714", doi = "10.1007/s40656-017-0164-z", volume = "39", pmcid = "PMC5660880" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170918-100744257, title = "A two-amino-acid substitution in the transcription factor RORγt disrupts its function in T\_H17 differentiation but not in thymocyte development", journal = "Nature Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170918-100744257", id = "record", issn = "1529-2908", doi = "10.1038/ni.3832", volume = "18", pmcid = "PMC5678981" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170202-145154883, title = "Bcl11b and combinatorial resolution of cell fate in the T-cell gene regulatory network", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170202-145154883", id = "record", issn = "0027-8424", doi = "10.1073/pnas.1610617114", volume = "114", pmcid = "PMC5468679" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20161128-134111050, title = "TET proteins regulate the lineage specification and TCR-mediated expansion of iNKT cells", journal = "Nature Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20161128-134111050", id = "record", issn = "1529-2908", doi = "10.1038/ni.3630", volume = "18", pmcid = "PMC5376256" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20160923-100429944, title = "Multiple Curricula for B Cell Developmental Programming", journal = "Immunity", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160923-100429944", id = "record", issn = "1074-7613", doi = "10.1016/j.immuni.2016.09.005", volume = "45" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20160816-102432005, title = "Irreversibility of T-cell specification: insights from computational modelling of a minimal network architecture", journal = "PLoS ONE", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160816-102432005", id = "record", issn = "1932-6203", doi = "10.1371/journal.pone.0161260", volume = "11", pmcid = "PMC4995000" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20161021-124515838, title = "Dissecting the transcriptional regulatory network for early T-cell commitment", journal = "European Journal of Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20161021-124515838", id = "record", issn = "0014-2980", doi = "10.1002/eji.201670200", volume = "46" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20160613-162442836, title = "Asynchronous combinatorial action of four regulatory factors activates Bcl11b for T cell commitment", journal = "Nature Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160613-162442836", id = "record", issn = "1529-2908", doi = "10.1038/ni.3514", volume = "17", pmcid = "PMC4955789" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20160425-152503200, title = "Hematopoiesis and T-cell specification as a model developmental system", journal = "Immunological Reviews", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160425-152503200", id = "record", issn = "0105-2896", doi = "10.1111/imr.12417", volume = "271", pmcid = "PMC4837658" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20160202-124600941, title = "Eric Davidson: Steps to A Gene Regulatory Network for Development", journal = "Developmental Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160202-124600941", id = "record", issn = "0012-1606", doi = "10.1016/j.ydbio.2016.01.020", volume = "412", pmcid = "PMC4828313" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20160429-141209078, title = "GATA3 induces human T-cell commitment by restraining Notch activity and repressing NK-cell fate", journal = "Nature Communications", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160429-141209078", id = "record", issn = "2041-1723", doi = "10.1038/ncomms11171", volume = "7", pmcid = "PMC4823830" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20160126-153717169, title = "Forging T-Lymphocyte Identity: Intersecting Networks of Transcriptional Control", journal = "Advances in Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160126-153717169", id = "record", issn = "0065-2776", doi = "10.1016/bs.ai.2015.09.002", volume = "129", pmcid = "PMC4747653" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20151027-160800977, title = "Developmental biologist Eric H. Davidson, 1937–2015", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:20151027-160800977", id = "record", issn = "0027-8424", doi = "10.1073/pnas.1518876112", volume = "112", pmcid = "PMC4640791" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150409-074847821, title = "Regulation of early T-lineage gene expression and developmental progression by the progenitor cell transcription factor PU.1", journal = "Genes and Development", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150409-074847821", id = "record", issn = "0890-9369", doi = "10.1101/gad.259879.115", volume = "29", pmcid = "PMC4403259" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20160218-133043286, title = "Immune Cell Identity: Perspective from a Palimpsest", journal = "Perspectives in Biology and Medicine", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160218-133043286", id = "record", issn = "1529-8795", doi = "10.1353/pbm.2015.0020", volume = "58", pmcid = "PMC4747652" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20140905-102102851, title = "GATA-3 Dose-Dependent Checkpoints in Early T Cell Commitment", journal = "Journal of Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140905-102102851", id = "record", issn = "0022-1767", doi = "10.4049/jimmunol.1301663", volume = "193", pmcid = "PMC4170028" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20140911-141135837, title = "Macrophage and T-cell fate control: Insights from tracking transcription factor dynamics in single cells", journal = "Experimental Hematology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140911-141135837", id = "record", issn = "0301-472X", doi = "10.1016/j.exphem.2014.07.054", volume = "42" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20140903-154240690, title = "Developmental gene networks: a triathlon on the course to T cell identity", journal = "Nature Reviews. Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140903-154240690", id = "record", issn = "1474-1733", doi = "10.1038/nri3702", volume = "14", pmcid = "PMC4153685" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20140408-092441274, title = "The chromatin landscape and transcription factors in T cell programming", journal = "Trends in Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140408-092441274", id = "record", issn = "1471-4906", doi = "10.1016/j.it.2014.03.001", volume = "35", pmcid = "PMC4039984" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20140130-091206404, title = "Transcriptional Control of Early T and B Cell Developmental Choices", journal = "Annual Review of Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140130-091206404", id = "record", issn = "0732-0582", doi = "10.1146/annurev-immunol-032712-100024", volume = "32", pmcid = "PMC3994230" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20140103-081036440, title = "Epigenetic mechanisms and developmental choice hierarchies in T-lymphocyte development", journal = "Briefings in Functional Genomics", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140103-081036440", id = "record", issn = "2041-2649", doi = "10.1093/bfgp/elt027", volume = "12", pmcid = "PMC3838197" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20131028-142315690, title = "Transcriptional Establishment of Cell-Type Identity: Dynamics and Causal Mechanisms of T-Cell Lineage Commitment", journal = "Cold Spring Harbor Symposia on Quantitative Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20131028-142315690", id = "record", issn = "0091-7451", doi = "10.1101/sqb.2013.78.020271", volume = "78", pmcid = "PMC3990665" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20130905-110028915, title = "Positive Feedback Between PU.1 and the Cell Cycle Controls Myeloid Differentiation", journal = "Science", url = "https://resolver.caltech.edu/CaltechAUTHORS:20130905-110028915", id = "record", issn = "0036-8075", doi = "10.1126/science.1240831", volume = "341", pmcid = "PMC3913367" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20131002-112656015, title = "A far downstream enhancer for murine Bcl11b controls its T-cell specific expression", journal = "Blood", url = "https://resolver.caltech.edu/CaltechAUTHORS:20131002-112656015", id = "record", issn = "0006-4971", doi = "10.1182/blood-2012-08-447839", volume = "122", pmcid = "PMC3739036" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20130905-132328526, title = "Transcriptional and epigenetic thresholds for entry to the T-cell developmental program", journal = "Experimental Hematology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20130905-132328526", id = "record", issn = "0301-472X", volume = "41" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20130506-110729222, title = "Loss of T Cell Progenitor Checkpoint Control Underlies Leukemia Initiation in Rag1-Deficient Nonobese Diabetic Mice", journal = "Journal of Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20130506-110729222", id = "record", issn = "0022-1767", doi = "10.4049/jimmunol.1202970", volume = "190", pmcid = "PMC3608698" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20130328-110147486, title = "Architecture of a lymphomyeloid developmental switch controlled by PU.1, Notch and Gata3", journal = "Development", url = "https://resolver.caltech.edu/CaltechAUTHORS:20130328-110147486", id = "record", issn = "0950-1991", doi = "10.1242/dev.088559", volume = "140", pmcid = "PMC3585658" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20130809-091457588, title = "GATA-3 locks the door to the B-cell option", journal = "Blood", url = "https://resolver.caltech.edu/CaltechAUTHORS:20130809-091457588", id = "record", issn = "0006-4971", doi = "10.1182/blood-2013-01-477737", volume = "121", pmcid = "PMC3591792" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20130107-112150916, title = "Computational modelling of T-cell formation kinetics: output regulated by initial proliferation-linked deferral of developmental competence", journal = "Journal of the Royal Society Interface", url = "https://resolver.caltech.edu/CaltechAUTHORS:20130107-112150916", id = "record", issn = "1742-5689", doi = "10.1098/rsif.2012.0774", volume = "10", pmcid = "PMC3565808" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20121204-103322403, title = "Ikaros represses and activates PU.1 cell-type-specifically through the multifunctional Sfpi1 URE and a myeloid specific enhancer", journal = "Oncogene", url = "https://resolver.caltech.edu/CaltechAUTHORS:20121204-103322403", id = "record", issn = "0950-9232", doi = "10.1038/onc.2011.597", volume = "31", pmcid = "PMC3679182" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120511-113721604, title = "Dynamic Transformations of Genome-wide Epigenetic Marking and Transcriptional Control Establish T Cell Identity", journal = "Cell", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120511-113721604", id = "record", issn = "0092-8674", doi = "10.1016/j.cell.2012.01.056", volume = "149", pmcid = "PMC3336965" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120515-105946198, title = "Transcriptional drivers of the T-cell lineage program", journal = "Current Opinion in Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120515-105946198", id = "record", issn = "0952-7915", doi = "10.1016/j.coi.2011.12.012", volume = "24", pmcid = "PMC3319509" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120120-120159296, title = "Regulatory gene network circuits underlying T cell development from multipotent progenitors", journal = "Wiley Interdisciplinary Reviews. Systems Biology and Medicine", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120120-120159296", id = "record", issn = "1939-5094", doi = "10.1002/wsbm.162", volume = "4", pmcid = "PMC3242926" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20110617-142146431, title = "T Cell Lineage Commitment: Identity and Renunciation", journal = "Journal of Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20110617-142146431", id = "record", issn = "0022-1767", doi = "10.4049/jimmunol.1003703", volume = "186", pmcid = "PMC3111953" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20110316-093514596, title = "Lineage Divergence at the First TCR-Dependent Checkpoint: Preferential γδ and Impaired αβ T Cell Development in Nonobese Diabetic Mice", journal = "Journal of Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20110316-093514596", id = "record", issn = "0022-1767", doi = "10.4049/jimmunol.1002630", volume = "186", pmcid = "PMC4087166" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20101108-095515654, title = "Lineage determination in the immune system", journal = "Immunological Reviews", url = "https://resolver.caltech.edu/CaltechAUTHORS:20101108-095515654", id = "record", issn = "0105-2896", doi = "10.1111/j.1600-065X.2010.00965.x", volume = "238", pmcid = "PMC3058842" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20101108-094429835, title = "Multilayered specification of the T-cell lineage fate", journal = "Immunological Reviews", url = "https://resolver.caltech.edu/CaltechAUTHORS:20101108-094429835", id = "record", issn = "0105-2896", doi = "10.1111/j.1600-065X.2010.00964.x", volume = "238", pmcid = "PMC2965335" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20100927-104747466, title = "Cell-Type-Specific Activation and Repression of PU.1 by a Complex of Discrete, Functionally Specialized cis-Regulatory Elements", journal = "Molecular and Cellular Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20100927-104747466", id = "record", issn = "0270-7306", doi = "10.1128/MCB.00354-10", volume = "30", pmcid = "PMC2950536" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20100719-105902148, title = "An Early T Cell Lineage Commitment Checkpoint Dependent on the Transcription Factor Bcl11b", journal = "Science", url = "https://resolver.caltech.edu/CaltechAUTHORS:20100719-105902148", id = "record", issn = "0036-8075", doi = "10.1126/science.1188989", volume = "329", pmcid = "PMC2935300" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20100709-164908797, title = "B cell specification from the genome up", journal = "Nature Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20100709-164908797", id = "record", issn = "1529-2908", doi = "10.1038/ni0710-572", volume = "11" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20100630-085544779, title = "Fine-Scale Staging of T Cell Lineage Commitment in Adult Mouse Thymus", journal = "Journal of Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20100630-085544779", id = "record", issn = "0022-1767", doi = "10.4049/jimmunol.1000679", volume = "185", pmcid = "PMC4091773" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200506-101543968, title = "Editorial overview", journal = "Current Opinion in Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200506-101543968", id = "record", issn = "0952-7915", doi = "10.1016/j.coi.2010.03.002", volume = "22" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20110330-143625327, title = "Lymphocyte development", journal = "Current Opinion in Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20110330-143625327", id = "record", issn = "0952-7915", doi = "10.1016/j.coi.2010.03.002", volume = "22" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170206-154015240, title = "Differential Transient and Long-Term Expression of DNA Sequences Introduced into T-Lymphocyte Lines", journal = "DNA", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170206-154015240", id = "record", issn = "0198-0238", doi = "10.1089/dna.1.1986.5.439", volume = "5" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20090922-094135817, title = "Decision by committee: new light on the CD4/CD8-lineage choice", journal = "Immunology and Cell Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20090922-094135817", id = "record", issn = "0818-9641", doi = "10.1038/icb.2008.100", volume = "87" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20090708-093942975, title = "Transcription factor expression dynamics of early T-lymphocyte specification and commitment", journal = "Developmental Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20090708-093942975", id = "record", issn = "0012-1606", doi = "10.1016/j.ydbio.2008.10.021", volume = "325", pmcid = "PMC2663971" } @article{https://resolver.caltech.edu/CaltechAUTHORS:GEOpnas08, title = "A gene regulatory network armature for T lymphocyte specification", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:GEOpnas08", id = "record", issn = "0027-8424", doi = "10.1073/pnas.0806501105", volume = "105", pmcid = "PMC2629331" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20090804-083343225, title = "Molecular mechanisms that control mouse and human TCR-αβ and TCR-γδ T cell development", journal = "Seminars In Immunopathology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20090804-083343225", id = "record", issn = "1863-2297", doi = "10.1007/s00281-008-0134-3", volume = "30" } @article{https://resolver.caltech.edu/CaltechAUTHORS:GUOblo08, title = "Core binding factors are necessary for natural killer cell development, and cooperate with Notch signaling during T cell specification", journal = "Blood", url = "https://resolver.caltech.edu/CaltechAUTHORS:GUOblo08", id = "record", issn = "0006-4971", doi = "10.1182/blood-2007-10-120261", volume = "112", pmcid = "PMC2481540" } @article{https://resolver.caltech.edu/CaltechAUTHORS:ROTsi08, title = "Competition and collaboration: GATA-3, PU.1, and Notch signaling in early T-cell fate determination", journal = "Seminars in Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:ROTsi08", id = "record", issn = "1044-5323", doi = "10.1016/j.smim.2008.07.006", volume = "20", pmcid = "PMC2634812" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170208-132658111, title = "Erg in stem cells: a function emerges", journal = "Nature Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170208-132658111", id = "record", issn = "1529-2908", doi = "10.1038/ni0708-714", volume = "9" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150318-105708662, title = "Launching the T-cell-lineage developmental programme", journal = "Nature Reviews. Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150318-105708662", id = "record", issn = "1474-1733", doi = "10.1038/nri2232", volume = "8", pmcid = "PMC3131407" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150317-124107825, title = "Mast cell lineage diversion of T lineage precursors by the essential T cell transcription factor GATA-3", journal = "Nature Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150317-124107825", id = "record", issn = "1529-2908", doi = "10.1038/ni1486", volume = "8", pmcid = "PMC3140173" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170210-153114201, title = "Molecular Dissection of Prethymic Progenitor Entry into the T Lymphocyte Developmental Pathway", journal = "Journal of Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170210-153114201", id = "record", issn = "0022-1767", doi = "10.4049/jimmunol.179.1.421", volume = "179" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170206-111340463, title = "Regulatory factors for initial T lymphocyte lineage specification", journal = "Current Opinion in Hematology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170206-111340463", id = "record", issn = "1065-6251", doi = "10.1097/MOH.0b013e3281de72a8", volume = "14" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170206-104749499, title = "Negotiation of the T Lineage Fate Decision by Transcription-Factor Interplay and Microenvironmental Signals", journal = "Immunity", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170206-104749499", id = "record", issn = "1074-7613", doi = "10.1016/j.immuni.2007.06.005", volume = "26" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150317-102100971, title = "Cell lineage regulators in B and T cell development", journal = "Nature Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150317-102100971", id = "record", issn = "1529-2908", doi = "10.1038/ni1461", volume = "8" } @article{https://resolver.caltech.edu/CaltechAUTHORS:FRApnas06, title = "Notch/Delta signaling constrains reengineering of pro-T cells by PU.1", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:FRApnas06", id = "record", issn = "0027-8424", doi = "10.1073/pnas.0601188103", volume = "103", pmcid = "PMC1567686" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170206-105418120, title = "The Basic Helix-Loop-Helix Transcription Factor HEBAlt Is Expressed in Pro-T Cells and Enhances the Generation of T Cell Precursors", journal = "Journal of Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170206-105418120", id = "record", issn = "0022-1767", doi = "10.4049/jimmunol.177.1.109", volume = "177" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170207-082859641, title = "Progression of regulatory gene expression states in fetal and adult pro-T-cell development", journal = "Immunological Reviews", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170207-082859641", id = "record", issn = "0105-2896", doi = "10.1111/j.0105-2896.2006.00355.x", volume = "209", pmcid = "PMC4157939" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170207-080106709, title = "Developmental and Molecular Characterization of Emerging β- and γδ-Selected Pre-T Cells in the Adult Mouse Thymus", journal = "Immunity", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170207-080106709", id = "record", issn = "1074-7613", doi = "10.1016/j.immuni.2005.11.012", volume = "24" } @article{https://resolver.caltech.edu/CaltechAUTHORS:ADAnar05, title = "Cell-type-specific epigenetic marking of the IL2 gene at a distal cis-regulatory region in competent, nontranscribing T-cells", journal = "Nucleic Acids Research", url = "https://resolver.caltech.edu/CaltechAUTHORS:ADAnar05", id = "record", issn = "0305-1048", doi = "10.1093/nar/gki637", volume = "33", pmcid = "PMC1142491" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170206-145342762, title = "Subversion of T lineage commitment by PU.1 in a clonal cell line system", journal = "Developmental Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170206-145342762", id = "record", issn = "0012-1606", doi = "10.1016/j.ydbio.2005.01.027", volume = "280" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170208-131541820, title = "Delayed, asynchronous, and reversible T-lineage specification induced by Notch/Delta signaling", journal = "Genes and Development", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170208-131541820", id = "record", issn = "0890-9369", doi = "10.1101/gad.1298305", volume = "19", pmcid = "PMC1080135" } @article{https://resolver.caltech.edu/CaltechAUTHORS:ROTari05, title = "Molecular Genetics of T Cell Development", journal = "Annual Review of Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:ROTari05", id = "record", issn = "0732-0582", doi = "10.1146/annurev.immunol.23.021704.115737", volume = "23" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20141119-102425463, title = "Thymic Regulation--Hidden in Plain Sight", journal = "Science", url = "https://resolver.caltech.edu/CaltechAUTHORS:20141119-102425463", id = "record", issn = "0036-8075", doi = "10.1126/science.1109501", volume = "307" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170215-075718505, title = "Deranged Early T Cell Development in Immunodeficient Strains of Nonobese Diabetic Mice", journal = "Journal of Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170215-075718505", id = "record", issn = "0022-1767", doi = "10.4049/jimmunol.173.9.5381", volume = "173" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170208-151304962, title = "Origins of lymphocyte developmental programs: transcription factor evidence", journal = "Seminars in Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170208-151304962", id = "record", issn = "1044-5323", doi = "10.1016/j.smim.2004.08.002", volume = "16" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170214-142347462, title = "Evolutionary Origins of Lymphocytes: Ensembles of T Cell and B Cell Transcriptional Regulators in a Cartilaginous Fish", journal = "Journal of Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170214-142347462", id = "record", issn = "0022-1767", doi = "10.4049/jimmunol.172.10.5851", volume = "172" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170215-085418955, title = "Preferential Activation of an IL-2 Regulatory Sequence Transgene in TCRγδ and NKT Cells: Subset-Specific Differences in IL-2 Regulation", journal = "Journal of Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170215-085418955", id = "record", issn = "0022-1767", doi = "10.4049/jimmunol.172.8.4691", volume = "172" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170215-074451553, title = "Localization of the Domains in Runx Transcription Factors Required for the Repression of CD4 in Thymocytes", journal = "Journal of Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170215-074451553", id = "record", issn = "0022-1767", doi = "10.4049/jimmunol.172.7.4359", volume = "172" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150513-091042195, title = "From totipotency to T in a dish", journal = "Nature Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150513-091042195", id = "record", issn = "1529-2908", doi = "10.1038/ni0404-359", volume = "5" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170207-111452870, title = "GATA-3 Expression Is Controlled by TCR Signals and Regulates CD4/CD8 Differentiation", journal = "Immunity", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170207-111452870", id = "record", issn = "1074-7613", doi = "10.1016/S1074-7613(03)00176-6", volume = "19" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170206-133114488, title = "Regulatory coding of lymphoid lineage choice by hematopoietic transcription factors", journal = "Current Opinion in Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170206-133114488", id = "record", issn = "0952-7915", doi = "10.1016/S0952-7915(03)00011-6", volume = "15" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170206-141657037, title = "T-lineage specification and commitment: a gene regulation perspective", journal = "Seminars in Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170206-141657037", id = "record", issn = "1044-5323", doi = "10.1016/S1044532302000787", volume = "14" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170208-153410241, title = "Lineage plasticity and commitment in T-cell development", journal = "Immunological Reviews", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170208-153410241", id = "record", issn = "0105-2896", doi = "10.1034/j.1600-065X.2002.18709.x", volume = "187" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170206-140435747, title = "Definition of Regulatory Network Elements for T Cell Development by Perturbation Analysis with PU.1 and GATA-3", journal = "Developmental Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170206-140435747", id = "record", issn = "0012-1606", doi = "10.1006/dbio.2002.0674", volume = "246" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170206-110847853, title = "Elements of Transcription Factor Network Design for T-Lineage Specification", journal = "Developmental Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170206-110847853", id = "record", issn = "0012-1606", doi = "10.1006/dbio.2002.0667", volume = "246" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170208-142853035, title = "Constitutive Expression of PU.1 in Fetal Hematopoietic Progenitors Blocks T Cell Development at the Pro-T Cell Stage", journal = "Immunity", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170208-142853035", id = "record", issn = "1074-7613", doi = "10.1016/S1074-7613(02)00277-7", volume = "16" } @article{https://resolver.caltech.edu/CaltechAUTHORS:ROTpnas01, title = "Mapping of complex regulatory elements by pufferfish/zebrafish transgenesis", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:ROTpnas01", id = "record", issn = "0027-8424", volume = "98", pmcid = "PMC34387" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170216-142557366, title = "A developmental transition in definitive erythropoiesis: erythropoietin expression is sequentially regulated by retinoic acid receptors and HNF4", journal = "Genes and Development", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170216-142557366", id = "record", issn = "0890-9369", doi = "10.1101/gad.871601", volume = "15", pmcid = "PMC312661" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20111116-111340077, title = "Complex expression patterns of lymphocyte-specific genes during the development of cartilaginous fish implicate unique lymphoid tissues in generating an immune repertoire", journal = "International Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20111116-111340077", id = "record", issn = "0953-8178", doi = "10.1093/intimm/13.4.567", volume = "13" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150408-095507286, title = "Notchless T cell maturation?", journal = "Nature Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150408-095507286", id = "record", issn = "1529-2908", doi = "10.1038/85231", volume = "2" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170213-104935777, title = "Differential Transcriptional Regulation of Individual TCR V Segments Before Gene Rearrangement", journal = "Journal of Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170213-104935777", id = "record", issn = "0022-1767", doi = "10.4049/jimmunol.166.3.1771", volume = "166" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170213-074814967, title = "A New Regulatory Region of the IL-2 Locus That Confers Position-Independent Transgene Expression", journal = "Journal of Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170213-074814967", id = "record", issn = "0022-1767", doi = "10.4049/jimmunol.166.3.1730", volume = "166" } @article{https://resolver.caltech.edu/CaltechAUTHORS:ANDpnas01.pdf, title = "Evolution of hematopoiesis: Three members of the PU.1 transcription factor family in a cartilaginous fish, Raja eglanteria", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:ANDpnas01.pdf", id = "record", issn = "0027-8424", doi = "10.1073/pnas.021478998", volume = "98", pmcid = "PMC14625" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170206-125607049, title = "Expression and Function of a Stem Cell Promoter for the Murine CBFα2 Gene: Distinct Roles and Regulation in Natural Killer and T Cell Development", journal = "Developmental Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170206-125607049", id = "record", issn = "0012-1606", doi = "10.1006/dbio.2000.9991", volume = "229" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170206-114648134, title = "Stepwise specification of lymphocyte developmental lineages", journal = "Current Opinion in Genetics and Development", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170206-114648134", id = "record", issn = "0959-437X", doi = "10.1016/S0959-437X(00)00098-8", volume = "10" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170209-113011357, title = "Lck Activity Controls CD4/CD8 T Cell Lineage Commitment", journal = "Immunity", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170209-113011357", id = "record", issn = "1074-7613", doi = "10.1016/S1074-7613(00)80184-3", volume = "12" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170208-155733709, title = "Transcriptional regulation of lymphocyte lineage commitment", journal = "Bioessays", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170208-155733709", id = "record", issn = "0265-9247", doi = "10.1002/(SICI)1521-1878(199909)21:9<726::AID-BIES4>3.0.CO;2-S", volume = "21" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120109-142434194, title = "Precise developmental regulation of Ets family transcription factors during specification and commitment to the T cell lineage", journal = "Development", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120109-142434194", id = "record", issn = "0950-1991", volume = "126" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120110-094338292, title = "Specific regulation of Fos family transcription factors in thymocytes at two developmental checkpoints", journal = "International Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120110-094338292", id = "record", issn = "0953-8178", doi = "10.1093/intimm/11.5.677", volume = "11" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120119-094044402, title = "Precocious expression of T cell functional response genes in vivo in primitive thymocytes before T lineage commitment", journal = "International Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120119-094044402", id = "record", issn = "0953-8178", doi = "10.1093/intimm/10.11.1623", volume = "10" } @article{https://resolver.caltech.edu/CaltechAUTHORS:WARnar98.991, title = "Chromatin remodeling of the interleukin-2 gene: distinct alterations in the proximal versus distal enhancer regions", journal = "Nucleic Acids Research", url = "https://resolver.caltech.edu/CaltechAUTHORS:WARnar98.991", id = "record", issn = "0305-1048", volume = "26", pmcid = "PMC147656" } @article{https://resolver.caltech.edu/CaltechAUTHORS:WANpnas98, title = "Cross-lineage expression of Ig-beta (B29) in thymocytes: Positive and negative gene regulation to establish T cell identity", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:WANpnas98", id = "record", issn = "0027-8424", volume = "95", pmcid = "PMC22652" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120117-131739949, title = "Spontaneous Expression of Interleukin-2 In Vivo in Specific Tissues of Young Mice", journal = "Developmental Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120117-131739949", id = "record", issn = "1044-6672", doi = "10.1155/1998/12421", volume = "5", pmcid = "PMC2275993" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170210-115202487, title = "Different Developmental Arrest Points in RAG-2 -/- and SCID Thymocytes on Two Genetic Backgrounds Developmental Choices and Cell Death Mechanisms before TCR Gene Rearrangement", journal = "Journal of Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170210-115202487", id = "record", issn = "0022-1767", volume = "158" } @article{https://resolver.caltech.edu/CaltechAUTHORS:ROTpnas96, title = "A dynamic assembly of diverse transcription factors integrates activation and cell-type information for interleukin 2 gene regulation", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:ROTpnas96", id = "record", issn = "0027-8424", volume = "93", pmcid = "PMC38432" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150114-094250570, title = "How T Cells Count", journal = "Science", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150114-094250570", id = "record", issn = "0036-8075", doi = "10.1126/science.273.5271.78", volume = "273" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170208-110702546, title = "Regulated expression and function of CD122 (interleukin-2/interleukin-15R-β) during lymphoid development", journal = "Blood", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170208-110702546", id = "record", issn = "0006-4971", volume = "87" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170213-081245647, title = "Apoptosis Induced by Serum Deprivation of PC12 Cells Is Not Preceded by Growth Arrest and Can Occur at Each Phase of the Cell Cycle", journal = "Cancer Research", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170213-081245647", id = "record", issn = "0008-5472", volume = "55" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170206-135119164, title = "Signaling mechanisms in thymocyte selection", journal = "Current Opinion in Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170206-135119164", id = "record", issn = "0952-7915", doi = "10.1016/0952-7915(94)90099-X", volume = "6" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120221-083046033, title = "Interleukin 2 transcription factors as molecular targets of cAMP inhibition: delayed inhibition kinetics and combinatorial transcription roles", journal = "Journal of Experimental Medicine", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120221-083046033", id = "record", issn = "0022-1007", doi = "10.1084/jem.179.3.931", volume = "179", pmcid = "PMC2191402" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120221-114430298, title = "Interleukin-2 transcription is regulated in vivo at the level of coordinated binding of both constitutive and regulated factors", journal = "Molecular and Cellular Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120221-114430298", id = "record", issn = "0270-7306", doi = "10.1128/MCB.14.3.2159", volume = "14", pmcid = "PMC358576" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170206-143349258, title = "Costimulation by interleukin-1 of multiple activation responses in a developmentally restricted subset of immature thymocytes", journal = "European Journal of Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170206-143349258", id = "record", issn = "0014-2980", doi = "10.1002/eji.1830240105", volume = "24" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170210-111022317, title = "Functional and phenotypic analysis of thymocytes in SCID mice. Evidence for functional response transitions before and after the SCID arrest point", journal = "Journal of Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170210-111022317", id = "record", issn = "0022-1767", volume = "151" } @article{https://resolver.caltech.edu/CaltechAUTHORS:CHEmcb93, title = "Molecular basis for developmental changes in interleukin-2 gene inducibility", journal = "Molecular and Cellular Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:CHEmcb93", id = "record", issn = "0270-7306", volume = "13", pmcid = "PMC358902" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120308-115336061, title = "Developmental and Anatomical Patterns Of IL-2 Gene Expression in Vivo in The Murine Thymus", journal = "Developmental Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120308-115336061", id = "record", issn = "1044-6672", doi = "10.1155/1993/86096", volume = "3", pmcid = "PMC2275923" } @article{https://resolver.caltech.edu/CaltechAUTHORS:NOVmcb92, title = "In vitro transfection of fresh thymocytes and T cells shows subset-specific expression of viral promoters", journal = "Molecular and Cellular Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:NOVmcb92", id = "record", issn = "0270-7306", volume = "12", pmcid = "PMC369593" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20141223-085601805, title = "cAMP inhibits induction of interleukin 2 but not of interleukin 4 in T cells", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:20141223-085601805", id = "record", issn = "0027-8424", doi = "10.1073/pnas.87.23.9353", volume = "87", pmcid = "PMC55163" } @article{https://resolver.caltech.edu/CaltechAUTHORS:NOVmcb90, title = "Interleukin-1 Synergy with Phosphoinositide Pathway Agonists for Induction of Interleukin-2 Gene Expression: Molecular Basis of Costimulation", journal = "Molecular and Cellular Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:NOVmcb90", id = "record", issn = "0270-7306", volume = "10", pmcid = "PMC362908" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170215-103934244, title = "Regulatory anatomy of the murine interleukin-2 gene", journal = "Nucleic Acids Research", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170215-103934244", id = "record", issn = "0305-1048", doi = "10.1093/nar/18.15.4523", volume = "18", pmcid = "PMC331273" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170206-130127645, title = "Death and transfiguration of cortical thymocytes: a reconsideration", journal = "Immunology Today", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170206-130127645", id = "record", issn = "0167-5699", doi = "10.1016/0167-5699(90)90047-D", volume = "11" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170207-105303837, title = "IL-2 gene inducibility in T cells before T cell receptor expression. Changes in signaling pathways and gene expression requirements during intrathymic maturation", journal = "Journal of Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170207-105303837", id = "record", issn = "0022-1767", volume = "144" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170214-152458305, title = "Changes in inducibility of IL-2 receptor alpha-chain and T cell-receptor expression during thymocyte differentiation in the mouse", journal = "Journal of Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170214-152458305", id = "record", issn = "0022-1767", volume = "142" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170206-131122567, title = "The long road to functional maturity for developing T cells", journal = "Immunology Today", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170206-131122567", id = "record", issn = "0167-5699", doi = "10.1016/0167-5699(89)90243-0", volume = "10" } @article{https://resolver.caltech.edu/CaltechAUTHORS:MCGpnas88, title = "Influence of activating stimulus on functional phenotype: Interleukin 2 mRNA accumulation differentially induced by ionophore and receptor ligands in subsets of murine T cells", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:MCGpnas88", id = "record", issn = "0027-8424", volume = "85", pmcid = "PMC282001" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170206-155009290, title = "Molecular Indices of Functional Competence in Developing T Cells", journal = "Immunological Reviews", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170206-155009290", id = "record", issn = "0105-2896", doi = "10.1111/j.1600-065X.1988.tb00758.x", volume = "104" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170210-113249636, title = "IL-2 receptor inducibility is blocked in cortical-type thymocytes", journal = "Journal of Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170210-113249636", id = "record", issn = "0022-1767", volume = "140" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170206-154511616, title = "Differential regulation of T cell receptor gamma genes in immature thymocyte populations", journal = "European Journal of Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170206-154511616", id = "record", issn = "0014-2980", doi = "10.1002/eji.1830170908", volume = "17" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170216-143807033, title = "Inducibility of interleukin-2 RNA expression in individual mature and immature T lymphocytes", journal = "EMBO Journal", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170216-143807033", id = "record", issn = "0261-4189", volume = "6", pmcid = "PMC553486" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170206-144350445, title = "Radiation leukemia virus and X-irradiation induce in C57BL/6 mice two distinct T-cell neoplasms: A growth factor-dependent lymphoma and a growth factor-independent lymphoma", journal = "Leukemia Research", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170206-144350445", id = "record", issn = "0145-2126", doi = "10.1016/0145-2126(87)90046-4", volume = "11" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170210-122538890, title = "Activation of T cell antigen receptor alpha- and beta-chain genes in the thymus: implications for the lineages of developing cortical thymocytes", journal = "Journal of Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170210-122538890", id = "record", issn = "0022-1767", volume = "137" } @article{https://resolver.caltech.edu/CaltechAUTHORS:LUGpnas86, title = "Early Precursor Thymocytes Can Produce Interleukin 2 upon Stimulation with Calcium Ionophore and Phorbol Ester", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:LUGpnas86", id = "record", issn = "0027-8424", volume = "83", pmcid = "PMC323184" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170206-145032179, title = "Differentiation and cell division in the mammalian thymus", journal = "Developmental Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170206-145032179", id = "record", issn = "0012-1606", doi = "10.1016/0012-1606(85)90114-9", volume = "112" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170210-142226362, title = "Proliferation of thymic stem cells with and without receptors for interleukin 2. Implications for intrathymic antigen recognition", journal = "Journal of Experimental Medicine", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170210-142226362", id = "record", issn = "0022-1007", doi = "10.1084/jem.161.5.1048", volume = "161", pmcid = "PMC2187600" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170208-153958374, title = "High-level secretion of interleukin 2 by a subset of proliferating thymic lymphoblasts", journal = "Journal of Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170208-153958374", id = "record", issn = "0022-1767", volume = "133" } @article{https://resolver.caltech.edu/CaltechAUTHORS:HAApnas84, title = "Mechanism of T-Cell Lymphomagenesis: Transformation of Growth-Factor-Dependent T-Lymphoblastoma Cells to Growth-Factor-Independent T-Lymphoma Cells", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:HAApnas84", id = "record", issn = "0027-8424", volume = "81", pmcid = "PMC344995" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170213-091823076, title = "Clonal proliferation unlinked to terminal deoxynucleotidyl transferase synthesis in thymocytes of young mice", journal = "Journal of Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170213-091823076", id = "record", issn = "0022-1767", volume = "130" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170210-131601098, title = "Lyt-2 glycoprotein is synthesized as a single molecular species", journal = "Journal of Experimental Medicine", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170210-131601098", id = "record", issn = "0022-1007", doi = "10.1084/jem.157.1.365", volume = "157", pmcid = "PMC2186898" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170206-145740897, title = "What is the role of T-lymphocyte surveillance in neoplastic disease?", journal = "American Journal of Surgery", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170206-145740897", id = "record", issn = "0002-9610", doi = "10.1016/0002-9610(82)90032-0", volume = "143" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170207-084442559, title = "A specific biosynthetic marker for immature thymic lymphoblasts. Active synthesis of thymus-leukemia antigen restricted to proliferating cells", journal = "Journal of Experimental Medicine", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170207-084442559", id = "record", issn = "0022-1007", doi = "10.1084/jem.155.1.140", volume = "155", pmcid = "PMC2186575" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170206-150254519, title = "Structure and expression of glycoproteins controlled by the Qa-1^a allele", journal = "Immunogenetics", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170206-150254519", id = "record", issn = "0093-7711", doi = "10.1007/BF00350118", volume = "14" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170207-073659882, title = {"Mature" thymocytes are not glucocorticoid-resistant in vitro}, journal = "Journal of Immunology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170207-073659882", id = "record", issn = "0022-1767", volume = "127" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170206-150723974, title = "Genetic polymorphism of murineβ\_2-microglobulin detected biochemically", journal = "Immunogenetics", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170206-150723974", id = "record", issn = "0093-7711", doi = "10.1007/BF01567773", volume = "11-11" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170209-084208618, title = "Expression of Differentiation Antigens in Subpopulations of Mouse Thymocytes: Regulation at the Level of de Novo Synthesis", journal = "Cell", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170209-084208618", id = "record", issn = "0092-8674", doi = "10.1016/0092-8674(80)90228-7", volume = "20" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170206-150943857, title = "In vitro maintenance of differentiation marker synthesis by subpopulations of mouse thymocytes", journal = "Journal of Supramolecular Structure", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170206-150943857", id = "record", issn = "0091-7419", doi = "10.1002/jss.400140310", volume = "14" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170213-072709317, title = "Synthesis and processing of molecules bearing thymus leukemia antigen", journal = "Journal of Experimental Medicine", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170213-072709317", id = "record", issn = "0022-1007", doi = "10.1084/jem.150.4.777", volume = "150", pmcid = "PMC2185687" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170213-071350586, title = "Production of a Discrete, Infectious, Double-stranded DNA by Reverse Transcription in Virions of Moloney Murine Leukemia Virus", journal = "Cold Spring Harbor Symposia on Quantitative Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170213-071350586", id = "record", issn = "0091-7451", doi = "10.1101/SQB.1979.043.01.093", volume = "43" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170209-082835063, title = "Heteroduplex Analysis of the Nonhomology Region between Moloney MuLV and the Dual Host Range Derivative HIX Virus", journal = "Cell", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170209-082835063", id = "record", issn = "0092-8674", doi = "10.1016/0092-8674(78)90350-1", volume = "14" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170206-152106075, title = "High frequency of aberrant expression of moloney murine leukemia virus in clonal infections", journal = "Cell", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170206-152106075", id = "record", issn = "0092-8674", doi = "10.1016/0092-8674(78)90245-3", volume = "14" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170207-111017078, title = "Analysis of a 5' Leader Sequence on Murine Leukemia Virus 21S RNA: Heteroduplex Mapping with Long Reverse Transcriptase Products", journal = "Cell", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170207-111017078", id = "record", issn = "0092-8674", doi = "10.1016/0092-8674(78)90318-5", volume = "13" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170207-083820520, title = "In vitro synthesis of infectious DNA of murine leukaemia virus", journal = "Nature", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170207-083820520", id = "record", issn = "0028-0836", doi = "10.1038/269122a0", volume = "269" } @article{https://resolver.caltech.edu/CaltechAUTHORS:ROTjvir77, title = "Increased Length of DNA Made by Virions of Murine Leukemia Virus at Limiting Magnesium Ion Concentration", journal = "Journal of Virology", url = "https://resolver.caltech.edu/CaltechAUTHORS:ROTjvir77", id = "record", issn = "0022-538X", volume = "21", pmcid = "PMC353803" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170206-144004711, title = "Ordered transcription of RNA tumor virus genomes", journal = "Journal of Molecular Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170206-144004711", id = "record", issn = "0022-2836", doi = "10.1016/0022-2836(76)90303-X", volume = "106" } @article{https://resolver.caltech.edu/CaltechAUTHORS:ROTjvir76, title = "Synthesis of Long, Representative DNA Copies of the Murine RNA Tumor Virus Genome", journal = "Journal of Virology", url = "https://resolver.caltech.edu/CaltechAUTHORS:ROTjvir76", id = "record", issn = "0022-538X", volume = "17", pmcid = "PMC515400" }