- Vo, Amy-Doan P.; Kim, Soo-Kyung; et el. (2023) Fully
activated structure of the sterol-bound Smoothened GPCR-Gi protein
complex; Proceedings of the National Academy of Sciences; Vol. 120;
No. 49; e2300919120; PMCID PMC10710022; 10.1073/pnas.2300919120
- Mendoza, Manuel; Tran, UyenPhuong; et el. (2022) Indolactam
Dipeptides as Nanomolar Gli Inhibitors; ACS Medicinal Chemistry
Letters; Vol. 13; No. 7; 1036-1042; PMCID PMC9290001; 10.1021/acsmedchemlett.1c00562
- Feng, Zhiping; Hom, Marisa E.; et el. (2022) Targeting
colorectal cancer with small-molecule inhibitors of ALDH1B1; Nature
Chemical Biology; Vol. 18; 1065-1075; 10.1038/s41589-022-01048-w
- Cheng, Yu-Shiuan; Zhang, Tianyi; et el. (2021) A
proteome-wide map of 20(S)-hydroxycholesterol interactors in cell
membranes; Nature Chemical Biology; Vol. 17; No. 12; 1271-1280;
PMCID PMC8607797; 10.1038/s41589-021-00907-2
- Zhang, Tianyi and Ondrus, Alison E. (2021) Structure,
Bonding, and Photoaffinity Labeling Applications of
Dialkyldiazirines; Synlett; Vol. 32; No. 11; 1053-1059; 10.1055/a-1437-8202
- Mafi, Amirhossein; Purohit, Rahul; et el. (2021) Hedgehog
proteins create a dynamic cholesterol interface; PLoS ONE; Vol. 16;
No. 2; Art. No. e0246814; 10.1371/journal.pone.0246814
- Tran, UyenPhuong; Zhang, Grace C.; et el. (2020) Small
Molecule Intervention in a Protein Kinase C–Gli Transcription Factor
Axis; ACS Chemical Biology; Vol. 15; No. 6; 1321-1327; PMCID
PMC8842554; 10.1021/acschembio.0c00355
- Hom, Marisa E.; Ondrus, Alison E.; et el. (2020) Bicyclic
imidazolium inhibitors of Gli transcription factor activity;
ChemMedChem; Vol. 15; No. 12; 1044-1049; PMCID PMC7311267; 10.1002/cmdc.202000169
- Purohit, Rahul; Peng, Daniel S.; et el. (2020) Dual
roles of the Sterol Recognition Region in Hedgehog protein
modification; Communications Biology; Vol. 3; Art. No. 250; PMCID
PMC7242414; 10.1038/s42003-020-0977-2
- Purohit, Rahul; Vielmas, Erika; et el. (2020) Defining
roles of the sterol recognition region in Hedgehog
cholesterolyation; FASEB Journal; Vol. 34; No. S1; 1; 10.1096/fasebj.2020.34.s1.09381
- Purohit, Rahul; Vielmas, Erika; et el. (2020) Defining
roles of the sterol recognition region in Hedgehog
cholesterolyation; FASEB Journal; Vol. 34; No. S1; 1; 10.1096/fasebj.2020.34.s1.09381
- Steinman, Jonathan B.; Santarossa, Cristina C.; et el. (2017) Chemical
structure-guided design of dynapyrazoles, potent cell-permeable dynein
inhibitors with a unique mode of action; eLife; Vol. 6; Art.
No. e25174; PMCID PMC5478271; 10.7554/eLife.25174
- Ondrus, Alison E.; Lee, Hsiao-lu D.; et el. (2012) Fluorescent
Saxitoxins for Live Cell Imaging of Single Voltage-Gated Sodium Ion
Channels beyond the Optical Diffraction Limit; Chemistry and
Biology; Vol. 19; No. 7; 902-912; PMCID PMC3731772; 10.1016/j.chembiol.2012.05.021
- Ondrus, Alison E.; Ümit Kaniskan, H.; et el. (2010) Dimerization
of functional pyrroloindolizines for the synthesis of complex myrmicarin
alkaloids; Tetrahedron; Vol. 66; No. 26; 4784-4795; PMCID
PMC2925304; 10.1016/j.tet.2010.04.006
- Ondrus, Alison E. and Movassaghi, Mohammad (2009) Total
synthesis and study of myrmicarin alkaloids; Chemical
Communications; Vol. 2009; No. 28; 4151-4165; PMCID PMC2987668; 10.1039/b903995n
- Ondrus, Alison E. and Movassaghi, Mohammad (2009) Reversible
Dimerization of (+)-Myrmicarin 215B; Organic Letters; Vol. 11;
No. 14; 2960-2963; PMCID PMC2752850; 10.1021/ol9008552
- Guggenheim, Evan R.; Ondrus, Alison E.; et el. (2008) Poly(ADP-ribose)
polymerase-1 activity facilitates the dissociation of nuclear proteins
from platinum-modified DNA; Bioorganic and Medicinal Chemistry; Vol.
16; No. 23; 10121-10128; PMCID PMC2662712; 10.1016/j.bmc.2008.09.074
- Movassaghi, Mohammad; Ondrus, Alison E.; et el. (2007) Efficient
and Stereoselective Dimerization of Pyrroloindolizine Derivatives
Inspired by a Hypothesis for the Biosynthesis of Complex Myrmicarin
Alkaloids; Journal of Organic Chemistry; Vol. 72; No. 26;
10065-10074; PMCID PMC2992888; 10.1021/jo701981q
- Ondrus, Alison E. and Movassaghi, Mohammad (2006) Dimerization
of (+)-myrmicarin 215B. A potential biomimetic approach to complex
myrmicarin alkaloids; Tetrahedron; Vol. 62; No. 22; 5287-5297; PMCID
PMC2904612; 10.1016/j.tet.2006.01.108
- Movassaghi, Mohammad and Ondrus, Alison
- Palladium-Catalyzed
Synthesis of N-Vinyl Pyrroles and Indoles; Journal of Organic
Chemistry; Vol. 70; No. 21; 8638-8641; PMCID PMC5548004; 10.1021/jo051450i