McMahon, Andrew

Combined from CaltechAUTHORS

Polonsky, Michal and Gerhardt, Louisa M. S., el al. (2024) Spatial transcriptomics defines injury specific microenvironments and cellular interactions in kidney regeneration and disease; Nature Communications; Vol. 15; No. 1; 7010; PMCID PMC11377535; 10.1038/s41467-024-51186-z
Der, Balint and Bugacov, Helena, el al. (2024) Cadherin Adhesion Complexes Direct Cell Aggregation in the Epithelial Transition of Wnt-Induced Nephron Progenitor Cells; Development; Vol. 151; No. 18; dev202303; 10.1242/dev.202303
Bugacov, Helena and Der, Balint, el al. (2024) Dose-dependent responses to canonical Wnt transcriptional complexes in the regulation of mammalian nephron progenitors; Development; Vol. 151; No. 18; dev202279; 10.1242/dev.202279
Niu, Xubo and Melendez, Delmy L., el al. (2024) A conserved transcription factor regulatory program promotes tendon fate; Developmental Cell; Vol. 59; 1-18; 10.1016/j.devcel.2024.08.006
Kim, Sunghyun and Koppitch, Kari, el al. (2024) Comparative single-cell analyses identify shared and divergent features of human and mouse kidney development; Developmental Cell; 10.1016/j.devcel.2024.07.013
Huang, Biao and Zeng, Zipeng, el al. (2024) Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease; Cell Stem Cell; Vol. 31; No. 6; 921-939.e17; 10.1016/j.stem.2024.04.002
Polonsky, Michal and Gerhardt, Louisa M. S., el al. (2023) Spatial transcriptomics defines injury-specific microenvironments in the adult mouse kidney and novel cellular interactions in regeneration and disease; bioRxiv; 10.1101/2023.11.22.568217
Xiong, Lingyun and Liu, Jing, el al. (2023) Direct androgen receptor control of sexually dimorphic gene expression in the mammalian kidney; Developmental Cell; Vol. 58; No. 21; 2338-2358.e5; PMCID PMC10873092; 10.1016/j.devcel.2023.08.010
Khalil, Natalie N. and Petersen, Andrew P., el al. (2023) User-friendly microfluidic system reveals native-like morphological and transcriptomic phenotypes induced by shear stress in proximal tubule epithelium; APL Bioengineering; Vol. 7; No. 3; 036106; 10.1063/5.0143614
Bugacov, Helena and Der, Balint, el al. (2023) Canonical Wnt transcriptional complexes are essential for induction of nephrogenesis but not maintenance or proliferation of nephron progenitors; 10.1101/2023.08.20.554044
Cippà, Pietro E. and McMahon, Andrew P. (2023) Proximal tubule responses to injury: interrogation by single-cell transcriptomics; Current Opinion in Nephrology & Hypertension; Vol. 32; No. 4; 352-358; 10.1097/mnh.0000000000000893
Xiong, Lingyun and Liu, Jing, el al. (2023) Direct androgen receptor regulation of sexually dimorphic gene expression in the mammalian kidney; PMCID PMC10187285; 10.1101/2023.05.06.539585
Huang, Biao and Zeng, Zipeng, el al. (2023) Modeling kidney development, disease, and plasticity with clonal expandable nephron progenitor cells and nephron organoids; 10.1101/2023.05.25.542343
Gerhardt, Louisa M.S. and Koppitch, Kari, el al. (2023) Lineage Tracing and Single-Nucleus Multiomics Reveal Novel Features of Adaptive and Maladaptive Repair after Acute Kidney Injury; Journal of the American Society of Nephrology; Vol. 34; No. 4; 554-571; 10.1681/asn.0000000000000057
Hojo, Hironori and Saito, Taku, el al. (2022) Runx2 regulates chromatin accessibility to direct the osteoblast program at neonatal stages; Cell Reports; Vol. 40; No. 10; 111315; 10.1016/j.celrep.2022.111315
Yang, Rui and Meyer, Amanda S., el al. (2022) A genetic model for in vivo proximity labelling of the mammalian secretome; Open Biology; Vol. 12; No. 8; 220149; 10.1098/rsob.220149
Tran, Tracy and Song, Cheng Jack, el al. (2022) A scalable organoid model of human autosomal dominant polycystic kidney disease for disease mechanism and drug discovery; Cell Stem Cell; Vol. 29; No. 7; 1083-1101.e7; 10.1016/j.stem.2022.06.005
Xu, Jun and Liu, Yifang, el al. (2022) Transcriptional and functional motifs defining renal function revealed by single-nucleus RNA sequencing; Proceedings of the National Academy of Sciences; Vol. 119; No. 25; e2203179119; PMCID PMC9231607; 10.1073/pnas.2203179119
Gerhardt, Louisa M.S. and McMahon, Andrew P. (2022) Identifying Common Molecular Mechanisms in Experimental and Human Acute Kidney Injury; Seminars in Nephrology; Vol. 42; No. 3; 151286; 10.1016/j.semnephrol.2022.10.012
Naved, Bilal A. and Bonventre, Joseph V., el al. (2022) Kidney repair and regeneration: perspectives of the NIDDK (Re)Building a Kidney consortium; Kidney International; Vol. 101; No. 5; 845-853; 10.1016/j.kint.2022.02.023
McMahon, Andrew P. and Ichida, Justin K. (2022) Repairing the blood-brain barrier; Science; Vol. 375; No. 6582; 715-716; 10.1126/science.abn7921
Gerhardt, Louisa M.S. and McMahon, Andrew P. (2021) Multi-omic approaches to acute kidney injury and repair; Current Opinion in Biomedical Engineering; Vol. 20; 100344; 10.1016/j.cobme.2021.100344
Miao, Zhen and Humphreys, Benjamin D., el al. (2021) Multi-omics integration in the age of million single-cell data; Nature Reviews Nephrology; Vol. 17; No. 11; 710-724; 10.1038/s41581-021-00463-x
Lindström, Nils O. and Sealfon, Rachel, el al. (2021) Spatial transcriptional mapping of the human nephrogenic program; Developmental Cell; Vol. 56; No. 16; 2381-2398.e6; 10.1016/j.devcel.2021.07.017
Gerhardt, Louisa M. S. and Liu, Jing, el al. (2021) Single-nuclear transcriptomics reveals diversity of proximal tubule cell states in a dynamic response to acute kidney injury; Proceedings of the National Academy of Sciences; Vol. 118; No. 27; e2026684118; 10.1073/pnas.2026684118
Zeng, Zipeng and Huang, Biao, el al. (2021) Generation of patterned kidney organoids that recapitulate the adult kidney collecting duct system from expandable ureteric bud progenitors; Nature Communications; Vol. 12; 3641; 10.1038/s41467-021-23911-5
Droujinine, Ilia A. and Meyer, Amanda S., el al. (2021) Proteomics of protein trafficking by in vivo tissue-specific labeling; Nature Communications; Vol. 12; 2382; 10.1038/s41467-021-22599-x
Guo, Qiuyu and Kim, Albert, el al. (2021) A β-catenin-driven switch in TCF/LEF transcription factor binding to DNA target sites promotes commitment of mammalian nephron progenitor cells; eLife; Vol. 10; e64444; 10.7554/elife.64444
Cornelius, Ryan J. and Sharma, Avika, el al. (2020) A novel distal convoluted tubule-specific Cre-recombinase driven by the NaCl cotransporter gene; American Journal of Physiology-Renal Physiology; Vol. 319; No. 3; F423-F435; PMCID PMC7509282; 10.1152/ajprenal.00101.2020
Legouis, David and Ricksten, Sven-Erick, el al. (2020) Altered proximal tubular cell glucose metabolism during acute kidney injury is associated with mortality; Nature Metabolism; Vol. 2; No. 8; 732-743; 10.1038/s42255-020-0238-1
Rutledge, Elisabeth A. and McMahon, Andrew P. (2020) Mutational analysis of genes with ureteric progenitor cell‐specific expression in branching morphogenesis of the mouse kidney; Developmental Dynamics; Vol. 249; No. 6; 765-774; 10.1002/dvdy.157
Liu, Jing and Kumar, Sanjeev, el al. (2020) Renoprotective and Immunomodulatory Effects of GDF15 following AKI Invoked by Ischemia-Reperfusion Injury; Journal of the American Society of Nephrology; Vol. 31; No. 4; 701-715; 10.1681/asn.2019090876
Rutledge, Elisabeth A. and Lindström, Nils O., el al. (2020) Genetic manipulation of ureteric bud tip progenitors in the mammalian kidney through an Adamts18 enhancer driven tet-on inducible system; Developmental Biology; Vol. 458; No. 2; 164-176; 10.1016/j.ydbio.2019.11.007
Ransick, Andrew and Lindström, Nils O., el al. (2019) Single-Cell Profiling Reveals Sex, Lineage, and Regional Diversity in the Mouse Kidney; Developmental Cell; Vol. 51; No. 3; 399-413.e7; 10.1016/j.devcel.2019.10.005
Kim, Albert D. and Lake, Blue B., el al. (2019) Cellular Recruitment by Podocyte-Derived Pro-migratory Factors in Assembly of the Human Renal Filter; iScience; Vol. 20; 402-414; 10.1016/j.isci.2019.09.029
Rutledge, Elisabeth A. and Parvez, Riana K., el al. (2019) Morphogenesis of the kidney and lung requires branch-tip directed activity of the Adamts18 metalloprotease; Developmental Biology; Vol. 454; No. 2; 156-169; 10.1016/j.ydbio.2019.06.012
Tran, Tracy and Lindström, Nils O., el al. (2019) In Vivo Developmental Trajectories of Human Podocyte Inform In Vitro Differentiation of Pluripotent Stem Cell-Derived Podocytes; Developmental Cell; Vol. 50; No. 1; 102-116.e6; 10.1016/j.devcel.2019.06.001
Cippà, Pietro E. and Liu, Jing, el al. (2019) A late B lymphocyte action in dysfunctional tissue repair following kidney injury and transplantation; Nature Communications; Vol. 10; No. 1; 1157; 10.1038/s41467-019-09092-2
Menshykau, Denis and Michos, Odyssé, el al. (2019) Image-based modeling of kidney branching morphogenesis reveals GDNF-RET based Turing-type mechanism and pattern-modulating WNT11 feedback; Nature Communications; Vol. 10; No. 1; 239; 10.1038/s41467-018-08212-8
Lindström, Nils O. and De Sena Brandine, Guilherme, el al. (2019) Single-Cell RNA Sequencing of the Adult Mouse Kidney: From Molecular Cataloging of Cell Types to Disease-Associated Predictions; American Journal of Kidney Diseases; Vol. 73; No. 1; 140-142; 10.1053/j.ajkd.2018.07.002
O'Brien, Lori L and Combes, Alexander N, el al. (2018) Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment; eLife; Vol. 7; 10.7554/elife.40392
Cippà, Pietro E. and Sun, Bo, el al. (2018) Transcriptional trajectories of human kidney injury progression; JCI Insight; Vol. 3; No. 22; 10.1172/jci.insight.123151
Hasenpusch-Theil, Kerstin and West, Stephen, el al. (2018) Gli3 controls the onset of cortical neurogenesis by regulating the radial glial cell cycle through Cdk6 expression; Development; Vol. 145; No. 17; 10.1242/dev.163147
Przepiorski, Aneta and Sander, Veronika, el al. (2018) A Simple Bioreactor-Based Method to Generate Kidney Organoids from Pluripotent Stem Cells; Stem Cell Reports; Vol. 11; No. 2; 470-484; 10.1016/j.stemcr.2018.06.018
Ramalingam, Harini and Fessler, Alicia R., el al. (2018) Disparate levels of beta-catenin activity determine nephron progenitor cell fate; Developmental Biology; Vol. 440; No. 1; 13-21; 10.1016/j.ydbio.2018.04.020
Lindström, Nils O. and De Sena Brandine, Guilherme, el al. (2018) Progressive Recruitment of Mesenchymal Progenitors Reveals a Time-Dependent Process of Cell Fate Acquisition in Mouse and Human Nephrogenesis; Developmental Cell; Vol. 45; No. 5; 651-660.e4; 10.1016/j.devcel.2018.05.010
Tan, Zhijia and Niu, Ben, el al. (2018) Synergistic co-regulation and competition by a SOX9-GLI-FOXA phasic transcriptional network coordinate chondrocyte differentiation transitions; PLOS Genetics; Vol. 14; No. 4; e1007346; 10.1371/journal.pgen.1007346
Lindström, Nils O. and Guo, Jinjin, el al. (2018) Conserved and Divergent Features of Mesenchymal Progenitor Cell Types within the Cortical Nephrogenic Niche of the Human and Mouse Kidney; Journal of the American Society of Nephrology; Vol. 29; No. 3; 806-824; 10.1681/asn.2017080890
Lindström, Nils O. and Tran, Tracy, el al. (2018) Conserved and Divergent Molecular and Anatomic Features of Human and Mouse Nephron Patterning; Journal of the American Society of Nephrology; Vol. 29; No. 3; 825-840; 10.1681/asn.2017091036
Lindström, Nils O. and McMahon, Jill A., el al. (2018) Conserved and Divergent Features of Human and Mouse Kidney Organogenesis; Journal of the American Society of Nephrology; Vol. 29; No. 3; 785-805; 10.1681/asn.2017080887
O'Brien, Lori L. and Guo, Qiuyu, el al. (2018) Transcriptional regulatory control of mammalian nephron progenitors revealed by multi-factor cistromic analysis and genetic studies; PLOS Genetics; Vol. 14; No. 1; e1007181; 10.1371/journal.pgen.1007181
Ryan, Danica and Sutherland, Megan R., el al. (2018) Development of the Human Fetal Kidney from Mid to Late Gestation in Male and Female Infants; EBioMedicine; Vol. 27; 275-283; 10.1016/j.ebiom.2017.12.016
Wegner, Kyle A. and Cadena, Mark T., el al. (2017) An immunohistochemical identification key for cell types in adult mouse prostatic and urethral tissue sections; PLOS ONE; Vol. 12; No. 11; e0188413; 10.1371/journal.pone.0188413
He, Xinjun and Bougioukli, Sofia, el al. (2017) Sox9 positive periosteal cells in fracture repair of the adult mammalian long bone; Bone; Vol. 103; 12-19; 10.1016/j.bone.2017.06.008
Liu, Jing and Kumar, Sanjeev, el al. (2017) Molecular characterization of the transition from acute to chronic kidney injury following ischemia/reperfusion; JCI Insight; Vol. 2; No. 18; 10.1172/jci.insight.94716
Naiman, Natalie and Fujioka, Kaoru, el al. (2017) Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development; Developmental Cell; Vol. 41; No. 4; 349-365.e3; 10.1016/j.devcel.2017.04.022
Minegishi, Katsura and Hashimoto, Masakazu, el al. (2017) A Wnt5 Activity Asymmetry and Intercellular Signaling via PCP Proteins Polarize Node Cells for Left-Right Symmetry Breaking; Developmental Cell; Vol. 40; No. 5; 439-452.e4; 10.1016/j.devcel.2017.02.010
Wu, Fujia and Zhang, Yu, el al. (2017) Hedgehog Signaling: From Basic Biology to Cancer Therapy; Cell Chemical Biology; Vol. 24; No. 3; 252-280; 10.1016/j.chembiol.2017.02.010
Oxburgh, Leif and Carroll, Thomas J., el al. (2017) (Re)Building a Kidney; Journal of the American Society of Nephrology; Vol. 28; No. 5; 1370-1378; 10.1681/asn.2016101077
Rutledge, Elisabeth A. and Benazet, Jean-Denis, el al. (2017) Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development; Development; 10.1242/dev.149112
Hoffmann, Andrew D. and Yang, Xinan Holly, el al. (2016) Correction: Foxf Genes Integrate Tbx5 and Hedgehog Pathways in the Second Heart Field for Cardiac Septation; PLOS Genetics; Vol. 12; No. 12; e1006533; 10.1371/journal.pgen.1006533
Hojo, Hironori and McMahon, Andrew P., el al. (2016) An Emerging Regulatory Landscape for Skeletal Development; Trends in Genetics; Vol. 32; No. 12; 774-787; 10.1016/j.tig.2016.10.001
He, Xinjun and Ohba, Shinsuke, el al. (2016) AP-1 family members act with Sox9 to promote chondrocyte hypertrophy; Development; Vol. 143; No. 16; 3012-3023; 10.1242/dev.134502
Lorberbaum, David S and Ramos, Andrea I, el al. (2016) An ancient yet flexible cis-regulatory architecture allows localized Hedgehog tuning by patched/Ptch1; eLife; Vol. 5; 10.7554/elife.13550
Hojo, Hironori and Ohba, Shinsuke, el al. (2016) Sp7/Osterix Is Restricted to Bone-Forming Vertebrates where It Acts as a Dlx Co-factor in Osteoblast Specification; Developmental Cell; Vol. 37; No. 3; 238-253; 10.1016/j.devcel.2016.04.002
Finch, Caleb E. and McMahon, Andrew P. (2016) Stem cells for all ages, yet hostage to aging; Stem Cell Investigation; Vol. 3; 11-11; 10.21037/sci.2016.04.02
O'Brien, Lori L. and Guo, Qiuyu, el al. (2016) Differential regulation of mouse and human nephron progenitors by the Six family of transcriptional regulators; Development; Vol. 143; No. 4; 595-608; 10.1242/dev.127175
Hettmer, Simone and Lin, Michael M., el al. (2016) Hedgehog-driven myogenic tumors recapitulate skeletal muscle cellular heterogeneity; Experimental Cell Research; Vol. 340; No. 1; 43-52; 10.1016/j.yexcr.2015.10.008
McMahon, Andrew P. (2016) Development of the Mammalian Kidney; Current Topics in Developmental Biology; 31-64; 10.1016/bs.ctdb.2015.10.010
Askary, Amjad and Mork, Lindsey, el al. (2015) Iroquois Proteins Promote Skeletal Joint Formation by Maintaining Chondrocytes in an Immature State; Developmental Cell; Vol. 35; No. 3; 358-365; 10.1016/j.devcel.2015.10.004
Kumar, Sanjeev and Liu, Jing, el al. (2015) Sox9 Activation Highlights a Cellular Pathway of Renal Repair in the Acutely Injured Mammalian Kidney; Cell Reports; Vol. 12; No. 8; 1325-1338; 10.1016/j.celrep.2015.07.034
Leguy, Aurelien M.A. and Frost, Jarvist Moore, el al. (2015) Correction: Corrigendum: The dynamics of methylammonium ions in hybrid organic–inorganic perovskite solar cells; Nature Communications; Vol. 6; No. 1; 7780; 10.1038/ncomms8780
Ohba, Shinsuke and He, Xinjun, el al. (2015) Distinct Transcriptional Programs Underlie Sox9 Regulation of the Mammalian Chondrocyte; Cell Reports; Vol. 12; No. 2; 229-243; 10.1016/j.celrep.2015.06.013
Leguy, Aurelien M. A. and Frost, Jarvist Moore, el al. (2015) The dynamics of methylammonium ions in hybrid organic–inorganic perovskite solar cells; Nature Communications; Vol. 6; No. 1; 7124; 10.1038/ncomms8124
Nishi, Yuichi and Zhang, Xiaoxiao, el al. (2015) A direct fate exclusion mechanism by Sonic hedgehog-regulated transcriptional repressors; Development; 10.1242/dev.124636
Li, Joan and Ariunbold, Usukhbayar, el al. (2015) Collecting Duct-Derived Cells Display Mesenchymal Stem Cell Properties and Retain Selective In Vitro and In Vivo Epithelial Capacity; Journal of the American Society of Nephrology; Vol. 26; No. 1; 81-94; 10.1681/asn.2013050517
Lai, Lick Pui and Lotinun, Sutada, el al. (2014) Stk11 (Lkb1) deletion in the osteoblast lineage leads to high bone turnover, increased trabecular bone density and cortical porosity; Bone; Vol. 69; 98-108; 10.1016/j.bone.2014.09.010
O'Brien, Lori L. and McMahon, Andrew P. (2014) Induction and patterning of the metanephric nephron; Seminars in Cell & Developmental Biology; Vol. 36; 31-38; 10.1016/j.semcdb.2014.08.014
Junker, Jan Philipp and Peterson, Kevin A., el al. (2014) A Predictive Model of Bifunctional Transcription Factor Signaling during Embryonic Tissue Patterning; Developmental Cell; Vol. 31; No. 4; 448-460; 10.1016/j.devcel.2014.10.017
Hoffmann, Andrew D. and Yang, Xinan Holly, el al. (2014) Foxf Genes Integrate Tbx5 and Hedgehog Pathways in the Second Heart Field for Cardiac Septation; PLoS Genetics; Vol. 10; No. 10; e1004604; 10.1371/journal.pgen.1004604
Junker, Jan Philipp and Noël, Emily S., el al. (2014) Genome-wide RNA Tomography in the Zebrafish Embryo; Cell; Vol. 159; No. 3; 662-675; 10.1016/j.cell.2014.09.038
Kobayashi, Akio and Mugford, Joshua W., el al. (2014) Identification of a Multipotent Self-Renewing Stromal Progenitor Population during Mammalian Kidney Organogenesis; Stem Cell Reports; Vol. 3; No. 4; 650-662; 10.1016/j.stemcr.2014.08.008
Grgic, Ivica and Krautzberger, A. Michaela, el al. (2014) Translational Profiles of Medullary Myofibroblasts during Kidney Fibrosis; Journal of the American Society of Nephrology; Vol. 25; No. 9; 1979-1990; 10.1681/asn.2013101143
Kumar, Sanjeev and Liu, Jing, el al. (2014) Defining the Acute Kidney Injury and Repair Transcriptome; Seminars in Nephrology; Vol. 34; No. 4; 404-417; 10.1016/j.semnephrol.2014.06.007
Lopez-Rios, Javier and Duchesne, Amandine, el al. (2014) Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs; Nature; Vol. 511; No. 7507; 46-51; 10.1038/nature13289
Little, Melissa H. and Brown, Dennis, el al. (2014) Defining Kidney Biology to Understand Renal Disease; Clinical Journal of the American Society of Nephrology; Vol. 9; No. 4; 809-811; 10.2215/cjn.10851013
Short, Kieran M. and Combes, Alexander N., el al. (2014) Global Quantification of Tissue Dynamics in the Developing Mouse Kidney; Developmental Cell; Vol. 29; No. 2; 188-202; 10.1016/j.devcel.2014.02.017
Liu, Jing and Krautzberger, A. Michaela, el al. (2014) Cell-specific translational profiling in acute kidney injury; Journal of Clinical Investigation; Vol. 124; No. 3; 1242-1254; 10.1172/jci72126
Wang, Yu and McMahon, Andrew P (2013) A novel site comes into sight; eLife; Vol. 2; 10.7554/elife.01680
Zhang, Xiaoxiao and Peterson, Kevin A., el al. (2013) Gene Regulatory Networks Mediating Canonical Wnt Signal-Directed Control of Pluripotency and Differentiation in Embryo Stem Cells; Stem Cells; Vol. 31; No. 12; 2667-2679; 10.1002/stem.1371
Rajurkar, M and Huang, H, el al. (2013) Distinct cellular origin and genetic requirement of Hedgehog-Gli in postnatal rhabdomyosarcoma genesis; Oncogene; Vol. 33; No. 46; 5370-5378; 10.1038/onc.2013.480
Lai, Lick Pui and Lilley, Brendan N., el al. (2013) Lkb1/Stk11 regulation of mTOR signaling controls the transition of chondrocyte fates and suppresses skeletal tumor formation; Proceedings of the National Academy of Sciences; Vol. 110; No. 48; 19450-19455; 10.1073/pnas.1309001110
DiRocco, Derek P. and Kobayashi, Akio, el al. (2013) Wnt4/β−Catenin Signaling in Medullary Kidney Myofibroblasts; Journal of the American Society of Nephrology; Vol. 24; No. 9; 1399-1412; 10.1681/asn.2012050512
Humphreys, Benjamin D. and Xu, Fengfeng, el al. (2013) Chronic epithelial kidney injury molecule-1 expression causes murine kidney fibrosis; Journal of Clinical Investigation; Vol. 123; No. 9; 4023-4035; 10.1172/jci45361
Holtz, Alexander M. and Peterson, Kevin A., el al. (2013) Essential role for ligand-dependent feedback antagonism of vertebrate hedgehog signaling by PTCH1, PTCH2 and HHIP1 during neural patterning; Development; Vol. 140; No. 16; 3423-3434; 10.1242/dev.095083
Hettmer, Simone and Teot, Lisa A, el al. (2013) Mutations in Hedgehog pathway genes in fetal rhabdomyomas; The Journal of Pathology; Vol. 231; No. 1; 44-52; 10.1002/path.4229
McMahon, Andrew P. and Hasso, Sean M. (2013) Filopodia: The Cellular Quills of Hedgehog Signaling?; Developmental Cell; Vol. 25; No. 4; 328-330; 10.1016/j.devcel.2013.05.008
O'Brien, Lori L and McMahon, Andrew P (2013) Progenitor programming in mammalian nephrogenesis; Nephrology; Vol. 18; No. 3; 177-179; 10.1111/nep.12027
Kamberov, Yana G. and Wang, Sijia, el al. (2013) Modeling Recent Human Evolution in Mice by Expression of a Selected EDAR Variant; Cell; Vol. 152; No. 4; 691-702; 10.1016/j.cell.2013.01.016
Mae, Shin-Ichi and Shono, Akemi, el al. (2013) Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells; Nature Communications; Vol. 4; No. 1; 1367; 10.1038/ncomms2378
Peterson, Kevin A. and Nishi, Yuichi, el al. (2012) Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning; Genes & Development; Vol. 26; No. 24; 2802-2816; 10.1101/gad.207142.112
Maatouk, Danielle M. and Mork, Lindsey, el al. (2012) Germ Cells Are Not Required to Establish the Female Pathway in Mouse Fetal Gonads; PLoS ONE; Vol. 7; No. 10; e47238; 10.1371/journal.pone.0047238
Kao, Robert M. and Vasilyev, Aleksandr, el al. (2012) Invasion of Distal Nephron Precursors Associates with Tubular Interconnection during Nephrogenesis; Journal of the American Society of Nephrology; Vol. 23; No. 10; 1682-1690; 10.1681/asn.2012030283
Park, Joo-Seop and Ma, Wenxiu, el al. (2012) Six2 and Wnt Regulate Self-Renewal and Commitment of Nephron Progenitors through Shared Gene Regulatory Networks; Developmental Cell; Vol. 23; No. 3; 637-651; 10.1016/j.devcel.2012.07.008
Wang, Yu and Davidow, Lance, el al. (2012) Glucocorticoid Compounds Modify Smoothened Localization and Hedgehog Pathway Activity; Chemistry and Biology; Vol. 19; No. 8; 972-982; 10.1016/j.chembiol.2012.06.012
Guha, Arjun and Vasconcelos, Michelle, el al. (2012) Neuroepithelial body microenvironment is a niche for a distinct subset of Clara-like precursors in the developing airways; Proceedings of the National Academy of Sciences; Vol. 109; No. 31; 12592-12597; 10.1073/pnas.1204710109
Yu, Jing and Valerius, M. Todd, el al. (2012) Identification of molecular compartments and genetic circuitry in the developing mammalian kidney; Development; Vol. 139; No. 10; 1863-1873; 10.1242/dev.074005
Wang, Yu and Arvanites, Anthony C., el al. (2012) Selective Identification of Hedgehog Pathway Antagonists By Direct Analysis of Smoothened Ciliary Translocation; ACS Chemical Biology; Vol. 7; No. 6; 1040-1048; 10.1021/cb300028a
Little, M. H. and McMahon, A. P. (2012) Mammalian Kidney Development: Principles, Progress, and Projections; Cold Spring Harbor Perspectives in Biology; Vol. 4; No. 5; a008300-a008300; 10.1101/cshperspect.a008300
Rajurkar, Mihir and De Jesus-Monge, Wilfredo E., el al. (2012) The activity of Gli transcription factors is essential for Kras-induced pancreatic tumorigenesis; Proceedings of the National Academy of Sciences; Vol. 109; No. 17; 10.1073/pnas.1114168109
Fabian, Steven L. and Penchev, Radostin R., el al. (2012) Hedgehog-Gli Pathway Activation during Kidney Fibrosis; The American Journal of Pathology; Vol. 180; No. 4; 1441-1453; 10.1016/j.ajpath.2011.12.039
Mork, Lindsey and Maatouk, Danielle M., el al. (2012) Temporal Differences in Granulosa Cell Specification in the Ovary Reflect Distinct Follicle Fates in Mice1; Biology of Reproduction; Vol. 86; No. 2; 10.1095/biolreprod.111.095208
Chong, H. Jonathan and Young, Nathan M., el al. (2012) Signaling by SHH rescues facial defects following blockade in the brain; Developmental Dynamics; Vol. 241; No. 2; 247-256; 10.1002/dvdy.23726
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McMahon, A.P. and Joyner, A.L., el al. (1992) The midbrain-hindbrain phenotype of Wnt-1−Wnt-1− mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum; Cell; Vol. 69; No. 4; 581-595; 10.1016/0092-8674(92)90222-x
Gavin, Brian J. and McMahon, Andrew P. (1992) Differential Regulation of the Wnt Gene Family during Pregnancy and Lactation Suggests a Role in Postnatal Development of the Mammary Gland; Molecular and Cellular Biology; Vol. 12; No. 5; 2418-2423; 10.1128/mcb.12.5.2418-2423.1992
Dickinson, Mary E. and McMahon, Andrew P. (1992) The role of Wnt genes in vertebrate development; Current Opinion in Genetics & Development; Vol. 2; No. 4; 562-566; 10.1016/s0959-437x(05)80172-8
Christian, Jan L. and McMahon, Jill A., el al. (1991) Xwnt-8, a Xenopus Wnt-1/int-1-related gene responsive to mesoderminducing growth factors, may play a role in ventral mesodermal patterning during embryogenesis; Development; Vol. 111; No. 4; 1045-1055; 10.1242/dev.111.4.1045
Christian, Jan L. and Gavin, Brian J., el al. (1991) Isolation of cDNAs partially encoding four Xenopus - proteins and characterization of their transient expression during embryonic development; Developmental Biology; Vol. 143; No. 2; 230-234; 10.1016/0012-1606(91)90073-c
Gavin, B J and McMahon, J A, el al. (1990) Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development.; Genes and Development; Vol. 4; No. 12b; 2319-2332; 10.1101/gad.4.12b.2319
McMahon, Andrew P. and Bradley, Allan (1990) The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain; Cell; Vol. 62; No. 6; 1073-1085; 10.1016/0092-8674(90)90385-r
McMahon, Andrew P. and Champion, Janet E., el al. (1990) Developmental expression of the putative transcription factor Egr-1 suggests that Egr-1 and c-fos are coregulated in some tissues; Development; Vol. 108; No. 2; 281-287; 10.1242/dev.108.2.281
McMahon, Jill A. and McMahon, Andrew P. (1989) Nucleotide sequence, chromosomal localization and developmental expression of the mouse int-1-related gene; Development; Vol. 107; No. 3; 643-650; 10.1242/dev.107.3.643
McMahon, Andrew P. and Moon, Randall T. (1989) Ectopic expression of the proto-oncogene int-1 in Xenopus embryos leads to duplication of the embryonic axis; Cell; Vol. 58; No. 6; 1075-1084; 10.1016/0092-8674(89)90506-0
McMahon, Andrew P. and Moon, Randall T. (1989) int-1 - a proto-oncogene involved in cell signalling; Development; Vol. 107; No. Supplement; 161-167; 10.1242/dev.107.supplement.161
Wilkinson, David G. and Bhatt, Sangita, el al. (1989) Expression pattern of the FGF-related proto-oncogene int-2 suggests multiple roles in fetal development; Development; Vol. 105; No. 1; 131-136; 10.1242/dev.105.1.131
Wilkinson, D. G. and Peters, G., el al. (1988) Expression of the FGF-related proto-oncogene int-2 during gastrulation and neurulation in the mouse.; The EMBO Journal; Vol. 7; No. 3; 691-695; 10.1002/j.1460-2075.1988.tb02864.x
McMahon, Andrew P. and Moon, Randall T. (1987) Structure and evolution of a non-erythroid spectrin, human α-fodrin; Biochemical Society Transactions; Vol. 15; No. 5; 804-807; 10.1042/bst0150804
Moon, Randall T. and McMahon, Andrew P. (1987) Composition and expression of spectrin‐based membrane skeletons in non‐erythroid cells; BioEssays; Vol. 7; No. 4; 159-164; 10.1002/bies.950070405
Wilkinson, David G. and Bailes, Juliet A., el al. (1987) Expression of the proto-oncogene int-1 is restricted to specific neural cells in the developing mouse embryo; Cell; Vol. 50; No. 1; 79-88; 10.1016/0092-8674(87)90664-7
McMahon, Andrew P. and Giebelhaus, Dawn H., el al. (1987) cDNA cloning, sequencing and chromosome mapping of a non-erythroid spectrin, human α-fodrin; Differentiation; Vol. 34; No. 1; 68-78; 10.1111/j.1432-0436.1987.tb00052.x
McMahon, Andrew P. and Flytzanis, Constantin N., el al. (1985) Introduction of Cloned DNA into Sea Urchin Egg Cytoplasm: Replication and Persistence during Embryogenesis; Developmental Biology; Vol. 108; No. 2; 420-430; 10.1016/0012-1606(85)90045-4
Flytzanis, Constantin N. and McMahon, Andrew P., el al. (1985) Persistence and Integration of Cloned DNA in Postembryonic Sea Urchins; Developmental Biology; Vol. 108; No. 2; 431-442; 10.1016/0012-1606(85)90046-6
McMahon, A. P. and Novak, T. J., el al. (1984) Inducible expression of a cloned heat shock fusion gene in sea urchin embryos; Proceedings of the National Academy of Sciences of the United States of America; Vol. 81; No. 23; 7490-7494; PMCID PMC392172
McMahon, A. P. and Novak, T. J., el al. (1984) Inducible expression of a cloned heat shock fusion gene in sea urchin embryos.; Proceedings of the National Academy of Sciences; Vol. 81; No. 23; 7490-7494; 10.1073/pnas.81.23.7490
McMahon, A. and Fosten, M., el al. (1983) X-chromosome inactivation mosaicism in the three germ layers and the germ line of the mouse embryo; Journal of Embryology and Experimental Morphology; Vol. 74; 207-220