[
    {
        "id": "data:2heky-yy833",
        "collection": "data",
        "collection_id": "2heky-yy833",
        "cite_using_url": "https://data.caltech.edu/records/2heky-yy833",
        "type": "dataset",
        "title": "Dataset for: Functional ultrasound imaging through a human cranial window for mesoscopic mapping of motor effector encoding within the sensorimotor cortex",
        "author": [
            {
                "family_name": "Lin",
                "given_name": "Lydia J.",
                "orcid": "0009-0002-8394-7621"
            },
            {
                "family_name": "Callier",
                "given_name": "Thierri",
                "orcid": "0000-0001-8645-2005"
            },
            {
                "family_name": "Heiles",
                "given_name": "Baptiste",
                "orcid": "0000-0001-9254-1741"
            },
            {
                "family_name": "Pejsa",
                "given_name": "Kelsie"
            },
            {
                "family_name": "Liu",
                "given_name": "Charles Y.",
                "orcid": "0000-0001-6423-8577"
            },
            {
                "family_name": "Shapiro",
                "given_name": "Mikhail G.",
                "orcid": "0000-0002-0291-4215"
            },
            {
                "family_name": "Andersen",
                "given_name": "Richard A.",
                "orcid": "0000-0002-7947-0472"
            }
        ],
        "abstract": "<p><span>This dataset accompanies the manuscript <strong>\"Functional ultrasound imaging through a human cranial window for mesoscopic mapping of motor effector encoding within the sensorimotor cortex.\"</strong></span><strong><span>&nbsp;</span></strong><span>It includes processed Doppler files (.mat files) and metadata about each session (\"ProjectRecordManuscript.json\").</span></p>\n<p><strong><span>Abstract </span></strong><span>of </span><span>\"Functional ultrasound imaging through a human cranial window for mesoscopic mapping of motor effector encoding within the sensorimotor cortex\"</span></p>\n<p><span>There are limited minimally invasive, high resolution neurorecording methods sensitive enough to detect single-trial movement-correlated neural activity. Functional ultrasound imaging (fUSI) provides transcutaneous recording of human neurovascular changes at high sensitivity and submillimeter spatial resolution when paired with acoustically transparent skull implants. Here, we demonstrate fUSI&rsquo;s ability to resolve multi-body-part and single digit movement encoding within the primary sensorimotor cortex in a participant with an acoustically transparent skull implant. We obtained fine-grained mappings of movement representation consistent with classic somatotopy and were able to resolve single-trial event-related activity, enabling single-trial decoding. Analysis of voxels important for decoding suggested differential encoding of single digit movement information across the different Brodmann areas. Finally, we show that these patterns can be approximated across different sessions, allowing for cross session decoding. This demonstrates that fUSI can reliably delineate motor representations with submillimeter resolution and bridges invasive electrophysiology and noninvasive hemodynamic imaging in humans. </span></p>",
        "doi": "10.22002/2heky-yy833",
        "publisher": "CaltechDATA",
        "publication_date": "2026-09-11"
    }
]