[ { "id": "authors:vvrrt-yf504", "collection": "authors", "collection_id": "vvrrt-yf504", "cite_using_url": "https://resolver.caltech.edu/CaltechAUTHORS:20230630-524987000.10", "type": "article", "title": "Evaluating the evidence for exponential quantum advantage in ground-state quantum chemistry", "author": [ { "family_name": "Lee", "given_name": "Seunghoon", "orcid": "0000-0003-3665-587X", "clpid": "Lee-Seunghoon" }, { "family_name": "Lee", "given_name": "Joonho", "orcid": "0000-0002-9667-1081", "clpid": "Lee-Joonho" }, { "family_name": "Zhai", "given_name": "Huanchen", "orcid": "0000-0003-0086-0388", "clpid": "Zhai-Huanchen" }, { "family_name": "Tong", "given_name": "Yu", "orcid": "0000-0002-7555-9373", "clpid": "Tong-Yu" }, { "family_name": "Dalzell", "given_name": "Alexander M.", "orcid": "0000-0002-3756-8500", "clpid": "Dalzell-Alexander-M" }, { "family_name": "Kumar", "given_name": "Ashutosh", "orcid": "0000-0001-7589-6030", "clpid": "Kumar-Ashutosh" }, { "family_name": "Helms", "given_name": "Phillip", "orcid": "0000-0002-6064-3193", "clpid": "Helms-Phillip" }, { "family_name": "Gray", "given_name": "Johnnie", "orcid": "0000-0001-9461-3024", "clpid": "Gray-Johnnie" }, { "family_name": "Cui", "given_name": "Zhi-Hao", "orcid": "0000-0002-7389-4063", "clpid": "Cui-Zhi-Hao" }, { "family_name": "Liu", "given_name": "Wenyuan", "orcid": "0000-0002-2003-8589", "clpid": "Liu-Wenyuan" }, { "family_name": "Kastoryano", "given_name": "Michael", "orcid": "0000-0001-5233-7957", "clpid": "Kastoryano-Michael-J" }, { "family_name": "Babbush", "given_name": "Ryan", "orcid": "0000-0001-6979-9533", "clpid": "Babbush-Ryan" }, { "family_name": "Preskill", "given_name": "John", "orcid": "0000-0002-2421-4762", "clpid": "Preskill-J" }, { "family_name": "Reichman", "given_name": "David R.", "orcid": "0000-0002-5265-5637", "clpid": "Reichman-David-R" }, { "family_name": "Campbell", "given_name": "Earl T.", "orcid": "0000-0002-3903-2734", "clpid": "Campbell-Earl-T" }, { "family_name": "Valeev", "given_name": "Edward F.", "orcid": "0000-0001-9923-6256", "clpid": "Valeev-Edward-F" }, { "family_name": "Lin", "given_name": "Lin", "orcid": "0000-0001-6860-9566", "clpid": "Lin-Lin" }, { "family_name": "Chan", "given_name": "Garnet Kin-Lic", "orcid": "0000-0001-8009-6038", "clpid": "Chan-Garnet-K-L" } ], "abstract": "Due to intense interest in the potential applications of quantum computing, it is critical to understand the basis for potential exponential quantum advantage in quantum chemistry. Here we gather the evidence for this case in the most common task in quantum chemistry, namely, ground-state energy estimation, for generic chemical problems where heuristic quantum state preparation might be assumed to be efficient. The availability of exponential quantum advantage then centers on whether features of the physical problem that enable efficient heuristic quantum state preparation also enable efficient solution by classical heuristics. Through numerical studies of quantum state preparation and empirical complexity analysis (including the error scaling) of classical heuristics, in both ab initio and model Hamiltonian settings, we conclude that evidence for such an exponential advantage across chemical space has yet to be found. While quantum computers may still prove useful for ground-state quantum chemistry through polynomial speedups, it may be prudent to assume exponential speedups are not generically available for this problem.", "doi": "10.1038/s41467-023-37587-6", "pmcid": "PMC10082187", "issn": "2041-1723", "publisher": "Nature Publishing Group", "publication": "Nature Communications", "publication_date": "2023-04-07", "volume": "14", "pages": "1952" }, { "id": "authors:3hv24-tg286", "collection": "authors", "collection_id": "3hv24-tg286", "cite_using_url": "https://resolver.caltech.edu/CaltechAUTHORS:20230605-335045000.28", "type": "article", "title": "Time-marching based quantum solvers for time-dependent linear differential equations", "author": [ { "family_name": "Fang", "given_name": "Di", "clpid": "Fang-Di" }, { "family_name": "Lin", "given_name": "Lin", "clpid": "Lin-Lin" }, { "family_name": "Tong", "given_name": "Yu", "clpid": "Tong-Yu" } ], "abstract": "The time-marching strategy, which propagates the solution from one time step to the next, is a natural strategy for solving time-dependent differential equations on classical computers, as well as for solving the Hamiltonian simulation problem on quantum computers. For more general homogeneous linear differential equations d/dt|\u03a8(t)>=A(t)|\u03a8(t)>,|\u03a8(0)>=|\u03a8_0>, a time-marching based quantum solver can suffer from exponentially vanishing success probability with respect to the number of time steps and is thus considered impractical. We solve this problem by repeatedly invoking a technique called the uniform singular value amplification, and the overall success probability can be lower bounded by a quantity that is independent of the number of time steps. The success probability can be further improved using a compression gadget lemma. This provides a path of designing quantum differential equation solvers that is alternative to those based on quantum linear systems algorithms (QLSA). We demonstrate the performance of the time-marching strategy with a high-order integrator based on the truncated Dyson series. The complexity of the algorithm depends linearly on the amplification ratio, which quantifies the deviation from a unitary dynamics. We prove that the linear dependence on the amplification ratio attains the query complexity lower bound and thus cannot be improved in the worst case. This algorithm also surpasses existing QLSA based solvers in three aspects: (1) A(t) does not need to be diagonalizable. (2) A(t) can be non-smooth, and is only of bounded variation. (3) It can use fewer queries to the initial state |\u03a8_0>. Finally, we demonstrate the time-marching strategy with a first-order truncated Magnus series, which simplifies the implementation compared to high-order truncated Dyson series approach, while retaining the aforementioned benefits. Our analysis also raises some open questions concerning the differences between time-marching and QLSA based methods for solving differential equations.", "doi": "10.22331/q-2023-03-20-955", "issn": "2521-327X", "publisher": "Verein zur F\u00f6rderung des Open Access Publizierens in den Quantenwissenschaften", "publication": "Quantum", "publication_date": "2023-03-20", "volume": "7", "pages": "955" }, { "id": "authors:vajev-exa14", "collection": "authors", "collection_id": "vajev-exa14", "cite_using_url": "https://resolver.caltech.edu/CaltechAUTHORS:20221017-12147700.16", "type": "article", "title": "A Theory of Quantum Subspace Diagonalization", "author": [ { "family_name": "Epperly", "given_name": "Ethan N.", "orcid": "0000-0003-0712-8296", "clpid": "Epperly-Ethan-N" }, { "family_name": "Lin", "given_name": "Lin", "orcid": "0000-0001-6860-9566", "clpid": "Lin-Lin" }, { "family_name": "Nakatsukasa", "given_name": "Yuji", "orcid": "0000-0001-7911-1501", "clpid": "Nakatsukasa-Yuji" } ], "abstract": "Quantum subspace diagonalization methods are an exciting new class of algorithms for solving large-scale eigenvalue problems using quantum computers. Unfortunately, these methods require the solution of an ill-conditioned generalized eigenvalue problem, with a matrix pencil corrupted by a nonnegligible amount of noise that is far above the machine precision. Despite pessimistic predictions from classical worst-case perturbation theories, these methods can perform reliably well if the generalized eigenvalue problem is solved using a standard truncation strategy. By leveraging and advancing classical results in matrix perturbation theory, we provide a theoretical analysis of this surprising phenomenon, proving that under certain natural conditions, a quantum subspace diagonalization algorithm can accurately compute the smallest eigenvalue of a large Hermitian matrix. We give numerical experiments demonstrating the effectiveness of the theory and providing practical guidance for the choice of truncation level. Our new results can also be of independent interest to solving eigenvalue problems outside the context of quantum computation.", "doi": "10.1137/21m145954x", "issn": "0895-4798", "publisher": "SIAM", "publication": "SIAM Journal on Matrix Analysis and Applications", "publication_date": "2022-09", "series_number": "3", "volume": "43", "issue": "3", "pages": "1263-1290" }, { "id": "authors:n9dda-zzj89", "collection": "authors", "collection_id": "n9dda-zzj89", "cite_using_url": "https://resolver.caltech.edu/CaltechAUTHORS:20220202-544261000", "type": "article", "title": "Pure State v-Representability of Density Matrix Embedding Theory", "author": [ { "family_name": "Faulstich", "given_name": "Fabian M.", "orcid": "0000-0003-4751-7544", "clpid": "Faulstich-Fabian-M" }, { "family_name": "Kim", "given_name": "Raehyun", "clpid": "Kim-Raehyun" }, { "family_name": "Cui", "given_name": "Zhi-Hao", "orcid": "0000-0002-7389-4063", "clpid": "Cui-Zhi-Hao" }, { "family_name": "Wen", "given_name": "Zaiwen", "clpid": "Wen-Zaiwen" }, { "family_name": "Chan", "given_name": "Garnet Kin-Lic", "orcid": "0000-0001-8009-6038", "clpid": "Chan-Garnet-K-L" }, { "family_name": "Lin", "given_name": "Lin", "orcid": "0000-0001-6860-9566", "clpid": "Lin-Lin" } ], "abstract": "Density matrix embedding theory (DMET) formally requires the matching of density matrix blocks obtained from high-level and low-level theories, but this is sometimes not achievable in practical calculations. In such a case, the global band gap of the low-level theory vanishes, and this can require additional numerical considerations. We find that both the violation of the exact matching condition and the vanishing low-level gap are related to the assumption that the high-level density matrix blocks are noninteracting pure-state v-representable (NI-PS-V), which assumes that the low-level density matrix is constructed following the Aufbau principle. To relax the NI-PS-V condition, we develop an augmented Lagrangian method to match the density matrix blocks without referring to the Aufbau principle. Numerical results for the 2D Hubbard and hydrogen model systems indicate that, in some challenging scenarios, the relaxation of the Aufbau principle directly leads to exact matching of the density matrix blocks, which also yields improved accuracy.", "doi": "10.1021/acs.jctc.1c01061", "issn": "1549-9618", "publisher": "American Chemical Society", "publication": "Journal of Chemical Theory and Computation", "publication_date": "2022-02-08", "series_number": "2", "volume": "18", "issue": "2", "pages": "851-864" }, { "id": "authors:s3yzs-0t557", "collection": "authors", "collection_id": "s3yzs-0t557", "cite_using_url": "https://resolver.caltech.edu/CaltechAUTHORS:20201204-110357020", "type": "article", "title": "NICER View of the 2020 Burst Storm and Persistent Emission of SGR 1935+2154", "author": [ { "family_name": "Younes", "given_name": "George", "orcid": "0000-0002-7991-028X", "clpid": "Younes-George" }, { "family_name": "G\u00fcver", "given_name": "Tolga", "orcid": "0000-0002-3531-9842", "clpid": "G\u00fcver-Tolga" }, { "family_name": "Kouveliotou", "given_name": "Chryssa", "orcid": "0000-0003-1443-593X", "clpid": "Kouveliotou-Chryssa" }, { "family_name": "Baring", "given_name": "Matthew G.", "orcid": "0000-0003-4433-1365", "clpid": "Baring-Matthew-G" }, { "family_name": "Hu", "given_name": "Chin-Ping", "orcid": "0000-0001-8551-2002", "clpid": "Hu-Chin-Ping" }, { "family_name": "Wadiasingh", "given_name": "Zorawar", "orcid": "0000-0002-9249-0515", "clpid": "Wadiasingh-Zorawar" }, { "family_name": "Begi\u00e7arslan", "given_name": "Beste", "orcid": "0000-0001-5072-8444", "clpid": "Begi\u00e7arslan-Beste" }, { "family_name": "Enoto", "given_name": "Teruaki", "orcid": "0000-0003-1244-3100", "clpid": "Enoto-Teruaki" }, { "family_name": "G\u00f6\u011f\u00fc\u015f", "given_name": "Ersin", "orcid": "0000-0002-5274-6790", "clpid": "G\u00f6\u011f\u00fc\u015f-Ersin" }, { "family_name": "Lin", "given_name": "Lin", "orcid": "0000-0002-0633-5325", "clpid": "Lin-Lin" }, { "family_name": "Harding", "given_name": "Alice K.", "orcid": "0000-0001-6119-859X", "clpid": "Harding-Alice-K" }, { "family_name": "van der Horst", "given_name": "Alexander J.", "orcid": "0000-0001-9149-6707", "clpid": "van-der-Horst-Alexander-J" }, { "family_name": "Majid", "given_name": "Walid A.", "orcid": "0000-0002-4694-4221", "clpid": "Majid-Walid-A" }, { "family_name": "Guillot", "given_name": "Sebastien", "orcid": "0000-0002-6449-106X", "clpid": "Guillot-Sebastien" }, { "family_name": "Malacaria", "given_name": "Christian", "orcid": "0000-0002-0380-0041", "clpid": "Malacaria-Christian" } ], "abstract": "We report on NICER observations of the magnetar SGR 1935+2154, covering its 2020 burst storm and long-term persistent emission evolution up to ~90 days postoutburst. During the first 1120 s taken on April 28 00:40:58 UTC, we detect over 217 bursts, corresponding to a burst rate of >0.2 bursts s\u207b\u00b9. Three hours later, the rate was 0.008 bursts s\u207b\u00b9, remaining at a comparatively low level thereafter. The T 90 burst duration distribution peaks at 840 ms; the distribution of waiting times to the next burst is fit with a lognormal with an average of 2.1 s. The 1\u201310 keV burst spectra are well fit by a blackbody, with an average temperature and area of kT = 1.7 keV and R\u00b2 = 53 km\u00b2. The differential burst fluence distribution over ~3 orders of magnitude is well modeled with a power-law form dN/dF \u221d F_(\u22121.5)^(\u00b10.1). The source persistent emission pulse profile is double-peaked hours after the burst storm. We find that the burst peak arrival times follow a uniform distribution in pulse phase, though the fast radio burst associated with the source aligns in phase with the brighter peak. We measure the source spin-down from heavy-cadence observations covering days 21\u201339 postoutburst, \u03bd\u02d9=\u22123.72(3)\u00d710\u207b\u00b9\u00b2 Hz s \u207b\u00b9, a factor of 2.7 larger than the value measured after the 2014 outburst. Finally, the persistent emission flux and blackbody temperature decrease rapidly in the early stages of the outburst, reaching quiescence 40 days later, while the size of the emitting area remains unchanged.", "doi": "10.3847/2041-8213/abc94c", "issn": "2041-8213", "publisher": "American Astronomical Society", "publication": "Astrophysical Journal Letters", "publication_date": "2020-12-01", "series_number": "2", "volume": "904", "issue": "2", "pages": "Art. No. L21" }, { "id": "authors:4s58n-bfc76", "collection": "authors", "collection_id": "4s58n-bfc76", "cite_using_url": "https://resolver.caltech.edu/CaltechAUTHORS:20190809-132030089", "type": "article", "title": "Projected density matrix embedding theory with applications to the two-dimensional Hubbard model", "author": [ { "family_name": "Wu", "given_name": "Xiaojie", "clpid": "Wu-Xiaojie" }, { "family_name": "Cui", "given_name": "Zhi-Hao", "orcid": "0000-0002-7389-4063", "clpid": "Cui-Zhi-Hao" }, { "family_name": "Tong", "given_name": "Yu", "clpid": "Tong-Yu" }, { "family_name": "Lindsey", "given_name": "Michael", "clpid": "Lindsey-M" }, { "family_name": "Chan", "given_name": "Garnet Kin-Lic", "orcid": "0000-0001-8009-6038", "clpid": "Chan-Garnet-K-L" }, { "family_name": "Lin", "given_name": "Lin", "orcid": "0000-0001-6860-9566", "clpid": "Lin-Lin" } ], "abstract": "Density matrix embedding theory (DMET) is a quantum embedding theory for strongly correlated systems. From a computational perspective, one bottleneck in DMET is the optimization of the correlation potential to achieve self-consistency, especially for heterogeneous systems of large size. We propose a new method, called projected DMET (p-DMET), which achieves self-consistency without needing to optimize the correlation potential. We demonstrate the performance of p-DMET on the two-dimensional Hubbard model.", "doi": "10.1063/1.5108818", "issn": "0021-9606", "publisher": "American Institute of Physics", "publication": "Journal of Chemical Physics", "publication_date": "2019-08-14", "series_number": "6", "volume": "151", "issue": "6", "pages": "Art. No. 064108" }, { "id": "authors:wye3v-fty53", "collection": "authors", "collection_id": "wye3v-fty53", "cite_using_url": "https://resolver.caltech.edu/CaltechAUTHORS:20181120-095849847", "type": "article", "title": "Membrane-separated electrochemical latrine wastewater treatment", "author": [ { "family_name": "Yang", "given_name": "Yang", "orcid": "0000-0003-3767-8029", "clpid": "Yang-Yang-ENVENG" }, { "family_name": "Lin", "given_name": "Lin", "orcid": "0000-0001-6860-9566", "clpid": "Lin-Lin" }, { "family_name": "Katebian Tse", "given_name": "Leda", "clpid": "Katebian-Tse-L" }, { "family_name": "Dong", "given_name": "Heng", "clpid": "Dong-Heng" }, { "family_name": "Yu", "given_name": "Shaokun", "clpid": "Yu-Shaokun" }, { "family_name": "Hoffmann", "given_name": "Michael R.", "orcid": "0000-0001-6495-1946", "clpid": "Hoffmann-M-R" } ], "abstract": "Electrolysis is demonstrated to be useful for onsite latrine wastewater treatment. Improved wastewater treatment efficiencies are achieved through the use of a combination of cation and anion exchange membranes (CEM/AEM) in electrochemical reactors. Compared to a membrane-free electrolysis cell, the separation of anodic and cathodic chambers using a CEM separator is shown to reduce energy consumption by 51% for COD removal and 87% for NH_4+ removal. Furthermore, 51% of the initial [NH_4+]_0 is recovered via electrodialysis. CEM-separated electrolysis is shown to produce 39% less ClO_3\u2212 and 92% less chlorinated organic by-products than in a membrane-free reactor. Helminth (Ascaris suum) eggs, which yield parasitic worms, are very resistant to conventional disinfection methods. Membrane-free electrolysis only inactivates 15% of the dosed helminth eggs (100 eggs per mL). In CEM-separated electrolysis, a combination of low pH and in situ chlorine production in the anodic chamber results in 85% inactivation of helminth eggs. In addition, H_2, which is produced in the cathodic chamber of the CEM-separated reactor, is directly converted to electricity using a hydrogen\u2013air fuel cell. The hydrogen energy produced during electrolysis is estimated to reduce the overall energy cost of operation by 20%. Recovery of 85% of the initial [PO_4^3\u2212]_0 and pH neutralization are achieved by treating the acidic effluent of a CEM-separated electrolysis cell in an AEM-separated electrolysis cell. A one-month continuous operation demonstrates the potential of using both the CEM and AEM during electrolysis to achieve more efficient wastewater treatment while, at the same time, recovering NH_4+ and PO_4^3\u2212, for eventual use as agricultural fertilizers.", "doi": "10.1039/c8ew00698a", "issn": "2053-1400", "publisher": "Royal Society of Chemistry", "publication": "Environmental Science: Water Research & Technology", "publication_date": "2019-01-01", "series_number": "1", "volume": "5", "issue": "1", "pages": "51-59" }, { "id": "authors:1xkba-ka856", "collection": "authors", "collection_id": "1xkba-ka856", "cite_using_url": "https://resolver.caltech.edu/CaltechAUTHORS:20170222-114618877", "type": "article", "title": "X-ray and radio observations of the magnetar SGR J1935+2154 during its 2014, 2015, and 2016 outbursts", "author": [ { "family_name": "Younes", "given_name": "George", "orcid": "0000-0002-7991-028X", "clpid": "Younes-G" }, { "family_name": "Kouveliotou", "given_name": "Chryssa", "orcid": "0000-0003-1443-593X", "clpid": "Kouveliotou-C" }, { "family_name": "Jaodand", "given_name": "Amruta", "orcid": "0000-0002-3850-6651", "clpid": "Jaodand-A" }, { "family_name": "Baring", "given_name": "Matthew G.", "clpid": "Baring-M-G" }, { "family_name": "van der Horst", "given_name": "Alexander J.", "orcid": "0000-0001-9149-6707", "clpid": "van-der-Horst-A-J" }, { "family_name": "Harding", "given_name": "Alice K.", "orcid": "0000-0001-6119-859X", "clpid": "Harding-A-K" }, { "family_name": "Hessels", "given_name": "Jason W. T.", "orcid": "0000-0003-2317-1446", "clpid": "Hessels-J-W-T" }, { "family_name": "Gehrels", "given_name": "Neil", "clpid": "Gehrels-N" }, { "family_name": "Gill", "given_name": "Ramandeep", "orcid": "0000-0003-0516-2968", "clpid": "Gill-R" }, { "family_name": "Huppenkothen", "given_name": "Daniela", "orcid": "0000-0002-1169-7486", "clpid": "Huppenkothen-D" }, { "family_name": "Granot", "given_name": "Jonathan", "orcid": "0000-0001-8530-8941", "clpid": "Granot-J" }, { "family_name": "G\u00f6\u011f\u00fc\u015f", "given_name": "Ersin", "orcid": "0000-0002-5274-6790", "clpid": "G\u00f6\u011f\u00fc\u015f-E" }, { "family_name": "Lin", "given_name": "Lin", "orcid": "0000-0001-6860-9566", "clpid": "Lin-Lin" } ], "abstract": "We analyzed broadband X-ray and radio data of the magnetar SGR J1935+2154 taken in the aftermath of its 2014, 2015, and 2016 outbursts. The source soft X-ray spectrum <10 keV is well described with a blackbody+power-law (BB+PL) or 2BB model during all three outbursts. Nuclear Spectroscopic Telescope Array observations revealed a hard X-ray tail, with a PL photon index \u0393 = 0.9, extending up to 50 keV, with flux comparable to the one detected <10 keV. Imaging analysis of Chandra data did not reveal small-scale extended emission around the source. Following the outbursts, the total 0.5\u201310 keV flux from SGR J1935+2154 increased in concordance to its bursting activity, with the flux at activation onset increasing by a factor of ~7 following its strongest 2016 June outburst. A Swift/X-Ray Telescope observation taken 1.5 days prior to the onset of this outburst showed a flux level consistent with quiescence. We show that the flux increase is due to the PL or hot BB component, which increased by a factor of 25 compared to quiescence, while the cold BB component kT = 0.47 keV remained more or less constant. The 2014 and 2015 outbursts decayed quasi-exponentially with timescales of ~40 days, while the stronger 2016 May and June outbursts showed a quick short-term decay with timescales of about four days. Our Arecibo radio observations set the deepest limits on the radio emission from a magnetar, with a maximum flux density limit of 14 \u03bcJy for the 4.6 GHz observations and 7 \u03bcJy for the 1.4 GHz observations. We discuss these results in the framework of the current magnetar theoretical models.", "doi": "10.3847/1538-4357/aa899a", "issn": "1538-4357", "publisher": "American Astronomical Society", "publication": "Astrophysical Journal", "publication_date": "2017-10-01", "series_number": "2", "volume": "847", "issue": "2", "pages": "Art. No. 85" }, { "id": "authors:vjn8b-2ge15", "collection": "authors", "collection_id": "vjn8b-2ge15", "cite_using_url": "https://resolver.caltech.edu/CaltechAUTHORS:20220323-565404000", "type": "article", "title": "Fob1 and Fob2 Proteins Are Virulence Determinants of Rhizopus oryzae via Facilitating Iron Uptake from Ferrioxamine", "author": [ { "family_name": "Liu", "given_name": "Mingfu", "clpid": "Liu-Mingfu" }, { "family_name": "Lin", "given_name": "Lin", "clpid": "Lin-Lin" }, { "family_name": "Gebremariam", "given_name": "Teclegiorgis", "clpid": "Gebremariam-Teclegiorgis" }, { "family_name": "Luo", "given_name": "Guanpingsheng", "clpid": "Luo-Guanpingsheng" }, { "family_name": "Skory", "given_name": "Christopher D.", "orcid": "0000-0001-6268-9104", "clpid": "Skory-Christopher-D" }, { "family_name": "French", "given_name": "Samuel W.", "clpid": "French-Samuel-W" }, { "family_name": "Chou", "given_name": "Tsui-Fen", "orcid": "0000-0003-2410-2186", "clpid": "Chou-Tsui-Fen" }, { "family_name": "Edwards", "given_name": "John E., Jr.", "clpid": "Edwards-John-E-Jr" }, { "family_name": "Ibrahim", "given_name": "Ashraf S.", "clpid": "Ibrahim-Ashraf-S" } ], "abstract": "Dialysis patients with chronic renal failure receiving deferoxamine for treating iron overload are uniquely predisposed for mucormycosis, which is most often caused by Rhizopus oryzae. Although the deferoxamine siderophore is not secreted by Mucorales, previous studies established that Rhizopus species utilize iron from ferrioxamine (iron-rich form of deferoxamine). Here we determined that the CBS domain proteins of Fob1 and Fob2 act as receptors on the cell surface of R. oryzae during iron uptake from ferrioxamine. Fob1 and Fob2 cell surface expression was induced in the presence of ferrioxamine and bound radiolabeled ferrioxamine. A R. oryzae strain with targeted reduced Fob1/Fob2 expression was impaired for iron uptake, germinating, and growing on medium with ferrioxamine as the sole source of iron. This strain also exhibited reduced virulence in a deferoxamine-treated, but not the diabetic ketoacidotic (DKA), mouse model of mucormycosis. The mechanism by which R. oryzae obtains iron from ferrioxamine involves the reductase/permease uptake system since the growth on ferrioxamine supplemented medium is associated with elevated reductase activity and the use of the ferrous chelator bathophenanthroline disulfonate abrogates iron uptake and growth on medium supplemented with ferrioxamine as a sole source of iron. Finally, R. oryzae mutants with reduced copies of the high affinity iron permease (FTR1) or with decreased FTR1 expression had an impaired iron uptake from ferrioxamine in vitro and reduced virulence in the deferoxamine-treated mouse model of mucormycosis. These two receptors appear to be conserved in Mucorales, and can be the subject of future novel therapy to maintain the use of deferoxamine for treating iron-overload.", "doi": "10.1371/journal.ppat.1004842", "pmcid": "PMC4431732", "issn": "1553-7374", "publisher": "Public Library of Science", "publication": "PLOS Pathogens", "publication_date": "2015-05", "series_number": "5", "volume": "11", "issue": "5", "pages": "Art. No. e1004842" }, { "id": "authors:a4683-93086", "collection": "authors", "collection_id": "a4683-93086", "cite_using_url": "https://resolver.caltech.edu/CaltechAUTHORS:20140623-090712146", "type": "article", "title": "Human NK Cells Licensed by Killer Ig Receptor Genes Have an Altered Cytokine Program That Modifies CD4+ T Cell Function", "author": [ { "family_name": "Lin", "given_name": "Lin", "orcid": "0000-0001-6860-9566", "clpid": "Lin-Lin" }, { "family_name": "Ma", "given_name": "Chao", "clpid": "Ma-Chao" }, { "family_name": "Wei", "given_name": "Bo", "clpid": "Wei-Bo" }, { "family_name": "Aziz", "given_name": "Najib", "clpid": "Aziz-Najib" }, { "family_name": "Rajalingam", "given_name": "Raja", "clpid": "Rajalingam-Raja" }, { "family_name": "Yusung", "given_name": "Susy", "clpid": "Yusung-Susy" }, { "family_name": "Erlich", "given_name": "Henry A.", "clpid": "Erlich-H-A" }, { "family_name": "Trachtenberg", "given_name": "Elizabeth A.", "clpid": "Trachtenberg-E-A" }, { "family_name": "Targan", "given_name": "Stephan R.", "clpid": "Targan-S-R" }, { "family_name": "McGovern", "given_name": "Dermot P. B.", "clpid": "McGovern-D-P-B" }, { "family_name": "Heath", "given_name": "James R.", "orcid": "0000-0001-5356-4385", "clpid": "Heath-J-R" }, { "family_name": "Braun", "given_name": "Jonathan", "clpid": "Braun-Jonathan" } ], "abstract": "NK cells are innate immune cells known for their cytolytic activities toward tumors and infections. They are capable of expressing diverse killer Ig-like receptors (KIRs), and KIRs are implicated in susceptibility to Crohn's disease (CD), a chronic intestinal inflammatory disease. However, the cellular mechanism of this genetic contribution is unknown. In this study, we show that the \"licensing\" of NK cells, determined by the presence of KIR2DL3 and homozygous HLA-C1 in host genome, results in their cytokine reprogramming, which permits them to promote CD4+ T cell activation and Th17 differentiation ex vivo. Microfluidic analysis of thousands of NK single cells and bulk secretions established that licensed NK cells are more polarized to proinflammatory cytokine production than unlicensed NK cells, including production of IFN-\u03b3, TNF-\u03b1, CCL-5, and MIP-1\u03b2. Cytokines produced by licensed NK augmented CD4+ T cell proliferation and IL-17A/IL-22 production. Ab blocking indicated a primary role for IFN-\u03b3, TNF-\u03b1, and IL-6 in the augmented T cell\u2013proliferative response. In conclusion, NK licensing mediated by KIR2DL2/3 and HLA-C1 elicits a novel NK cytokine program that activates and induces proinflammatory CD4+ T cells, thereby providing a potential biologic mechanism for KIR-associated susceptibility to CD and other chronic inflammatory diseases.", "doi": "10.4049/jimmunol.1400093", "pmcid": "PMC4096688", "issn": "0022-1767", "publisher": "American Association of Immunologists", "publication": "Journal of Immunology", "publication_date": "2014-06-16", "series_number": "2", "volume": "193", "issue": "2", "pages": "940-949" }, { "id": "authors:jt6zn-q9c21", "collection": "authors", "collection_id": "jt6zn-q9c21", "cite_using_url": "https://resolver.caltech.edu/CaltechAUTHORS:20130604-085130734", "type": "article", "title": "SN 2009ip: Constraints on the Progenitor Mass-loss Rate", "author": [ { "family_name": "Ofek", "given_name": "E. O.", "orcid": "0000-0002-6786-8774", "clpid": "Ofek-E-O" }, { "family_name": "Lin", "given_name": "L.", "orcid": "0000-0001-6860-9566", "clpid": "Lin-Lin" }, { "family_name": "Kouveliotou", "given_name": "C.", "orcid": "0000-0003-1443-593X", "clpid": "Kouveliotou-C" }, { "family_name": "Younes", "given_name": "G.", "orcid": "0000-0002-7991-028X", "clpid": "Younes-G" }, { "family_name": "G\u00f6\u011f\u00fc\u015f", "given_name": "E.", "orcid": "0000-0002-5274-6790", "clpid": "G\u00f6\u011f\u00fc\u015f-E" }, { "family_name": "Kasliwal", "given_name": "M. M.", "orcid": "0000-0002-5619-4938", "clpid": "Kasliwal-M-M" }, { "family_name": "Cao", "given_name": "Y.", "orcid": "0000-0002-8036-8491", "clpid": "Cao-Yi" } ], "abstract": "Some supernovae (SNe) show evidence for mass-loss events taking place prior to their explosions. Measuring their pre-outburst mass-loss rates provides essential information regarding the mechanisms that are responsible for these events. Here we present XMM-Newton and Swift X-ray observations taken after the latest, and presumably the final, outburst of SN 2009ip. We use these observations as well as new near-infrared and visible-light spectra and published radio and visible-light observations to put six independent order-of-magnitude constraints on the mass-loss rate of the SN progenitor prior to the explosion. Our methods utilize the X-ray luminosity, the bound-free absorption, the H\u03b1 luminosity, the SN rise time, free-free absorption, and the bolometric luminosity of the outburst detected prior to the explosion. Assuming spherical mass loss with a wind-density profile, we estimate that the effective mass-loss rate from the progenitor was between 10^(\u20133) and 10^(\u20132) M_\u2609 yr^(\u20131), over a few years prior to the explosion, with a velocity of ~10^3 km s^(\u20131). This mass-loss rate corresponds to a total circumstellar matter (CSM) mass of ~0.04 M_\u2609, within 6 \u00d7 10^(15) cm of the SN. We note that the mass-loss rate estimate based on the H\u03b1 luminosity is higher by an order of magnitude. This can be explained if the narrow-line H\u03b1 component is generated at radii larger than the shock radius, or if the CSM has an aspherical geometry. We discuss simple geometries which are consistent with our results.", "doi": "10.1088/0004-637X/768/1/47", "issn": "0004-637X", "publisher": "American Astronomical Society", "publication": "Astrophysical Journal", "publication_date": "2013-05-01", "series_number": "1", "volume": "768", "issue": "1", "pages": "Art. No. 47" }, { "id": "authors:tchb9-z2s10", "collection": "authors", "collection_id": "tchb9-z2s10", "cite_using_url": "https://resolver.caltech.edu/CaltechAUTHORS:20130912-102144974", "type": "article", "title": "Genetically-determined cytokine programs of human NK cells uncover a novel mechanism of NK cells and Killer cell IgG-like Receptor genes in Crohn's Disease susceptibility", "author": [ { "family_name": "Lin", "given_name": "Lin", "orcid": "0000-0001-6860-9566", "clpid": "Lin-Lin" }, { "family_name": "Ma", "given_name": "Chao", "clpid": "Ma-Chao" }, { "family_name": "Wei", "given_name": "Bo", "clpid": "Wei-Bo" }, { "family_name": "Rajalingam", "given_name": "Raja", "clpid": "Rajalingam-Raja" }, { "family_name": "Yusung", "given_name": "Susy", "clpid": "Yusung-Susy" }, { "family_name": "Trachtenberg", "given_name": "Elizabeth", "clpid": "Trachtenberg-E-A" }, { "family_name": "Targan", "given_name": "Stephan", "clpid": "Targan-S-R" }, { "family_name": "McGovern", "given_name": "Dermot", "clpid": "McGovern-D-P-B" }, { "family_name": "Braun", "given_name": "Jonathan", "clpid": "Braun-Jonathan" } ], "abstract": "Mucosal innate lymphocyte subsets have emerged as an important new factor in CD\npathogenesis, but the role of NK cells is poorly understood. A recent genetic study\nidentified the KIR gene KIR2DL2/3 as a risk factor for CD in the genetic context of its ligand\nHLA-C1. However, the biologic mechanism of this genetic contribution is unknown. NK cells\nare mainly known for their cytolytic function, but recent work indicates that strong KIR/HLA\ninteractions that induce NK \"licensing\" augment NK cytotoxicity but also IFN-\u03b3 production.\nWe therefore tested the hypothesis that human NK licensing by KIR2DL2/3 and HLA-C1\ninduces a broader cytokine program that modifies the threshold of pro-inflammatory T cell\nactivation. Single cell multiplex functional proteomics revealed that licensed and unlicensed\nNK cells had strikingly distinct cytokine programs. Licensed NK cells were distinguished by\nhigh-output, proinflammatory, poly-cytokine expression. Select cytokine among this output\nfully accounted for their unique capacity, unlike unlicensed NK cells, to efficiently augment\nantigenic CD4+ T cell proliferation and induce CD4+ T cell IL-17A production. In\nconclusion, NK licensing mediated by KIR2DL2/3 and HLA-C1 elicits a novel cytokine\nprogram of NK cells that activates and induces pro-inflammatory CD4+ T cells, and\ntherefore provides a predisposing biologic mechanism for this KIR-associated susceptibility\nto CD and other chronic inflammatory syndromes.", "issn": "0022-1767", "publisher": "American Association of Immunologists", "publication": "Journal of Immunology", "publication_date": "2013-05-01", "volume": "190", "pages": "136.13" }, { "id": "authors:jn1c4-r8268", "collection": "authors", "collection_id": "jn1c4-r8268", "cite_using_url": "https://resolver.caltech.edu/CaltechAUTHORS:20121030-104805260", "type": "article", "title": "KIR-mediated NK education mediates KIR-associated Crohn's disease susceptibility", "author": [ { "family_name": "Lin", "given_name": "Lin", "orcid": "0000-0001-6860-9566", "clpid": "Lin-Lin" }, { "family_name": "Ma", "given_name": "C.", "clpid": "Ma-Chao" }, { "family_name": "Aziz", "given_name": "N.", "clpid": "Aziz-Najib" }, { "family_name": "Rajalingam", "given_name": "Raja", "clpid": "Rajalingam-Raja" }, { "family_name": "Targan", "given_name": "Stephan", "clpid": "Targan-S-R" }, { "family_name": "McGovern", "given_name": "Dermot", "clpid": "McGovern-D-P-B" }, { "family_name": "Braun", "given_name": "Jonathan", "clpid": "Braun-Jonathan" } ], "abstract": "Purpose/Objective: Natural Killer (NK) cells are innate effector lymphocytes\nin the host response to infections and tumors through a\nvariety of activating and inhibitory receptors. NK cells require education\nby self-human leukocyte antigen (HLA) class I molecules\nthrough Killer cell Immunoglobulin-like receptors (KIRs) to gain\nproficient responses. Yet, it remains unknown whether and how KIR-mediated\nNK education contributes to chronic inflammation in humans.", "doi": "10.1111/imm.12002", "issn": "0019-2805", "publisher": "Blackwell Publishing", "publication": "Immunology", "publication_date": "2012-09", "series_number": "S1", "volume": "137", "issue": "S1", "pages": "533-533" }, { "id": "authors:bjwt7-7r363", "collection": "authors", "collection_id": "bjwt7-7r363", "cite_using_url": "https://resolver.caltech.edu/CaltechAUTHORS:20120813-104634830", "type": "article", "title": "Intestinal Microbes Affect Phenotypes and Functions of Invariant Natural Killer T Cells in Mice", "author": [ { "family_name": "Wingender", "given_name": "Gerhard", "clpid": "Wingender-Gerhard" }, { "family_name": "Stepniak", "given_name": "Dariusz", "clpid": "Stepniak-Dariusz" }, { "family_name": "Krebs", "given_name": "Philippe", "clpid": "Krebs-Philippe" }, { "family_name": "Lin", "given_name": "Lin", "orcid": "0000-0001-6860-9566", "clpid": "Lin-Lin" }, { "family_name": "McBride", "given_name": "Sarah", "clpid": "McBride-Sarah" }, { "family_name": "Wei", "given_name": "Bo", "clpid": "Wei-Bo" }, { "family_name": "Braun", "given_name": "Jonathan", "clpid": "Braun-Jonathan" }, { "family_name": "Mazmanian", "given_name": "Sarkis K.", "orcid": "0000-0003-2713-1513", "clpid": "Mazmanian-S-K" }, { "family_name": "Kronenberg", "given_name": "Mitchell", "clpid": "Kronenberg-Mitchell" } ], "abstract": "Background & Aims: Invariant natural killer T (iNKT) cells undergo canonical, V\u03b114\u2013J\u03b118 rearrangement of the T-cell receptor (TCR) in mice; this form of the TCR recognizes glycolipids presented by CD1d. iNKT cells mediate many different immune reactions. Their constitutive activated and memory phenotype and rapid initiation of effector functions after stimulation indicate previous antigen-specific stimulation. However, little is known about this process. We investigated whether symbiotic microbes can determine the activated phenotype and function of iNKT cells. \n\nMethods: We analyzed the numbers, phenotypes, and functions of iNKT cells in germ-free mice, germ-free mice reconstituted with specified bacteria, and mice housed in specific pathogen-free environments. \n\nResults: Specific pathogen-free mice, obtained from different vendors, have different intestinal microbiota. iNKT cells isolated from these mice differed in TCR V\u03b27 frequency and cytokine response to antigen, which depended on the environment. iNKT cells isolated from germ-free mice had a less mature phenotype and were hyporesponsive to activation with the antigen \u03b1-galactosylceramide. Intragastric exposure of germ-free mice to Sphingomonas bacteria, which carry iNKT cell antigens, fully established phenotypic maturity of iNKT cells. In contrast, reconstitution with Escherichia coli, which lack specific antigens for iNKT cells, did not affect the phenotype of iNKT cells. The effects of intestinal microbes on iNKT cell responsiveness did not require Toll-like receptor signals, which can activate iNKT cells independently of TCR stimulation. \n\nConclusions: Intestinal microbes can affect iNKT cell phenotypes and functions in mice.", "doi": "10.1053/j.gastro.2012.04.017", "pmcid": "PMC3404247", "issn": "0016-5085", "publisher": "AGA Institute", "publication": "Gastroenterology", "publication_date": "2012-08", "series_number": "2", "volume": "143", "issue": "2", "pages": "418-428" }, { "id": "authors:aar94-yj226", "collection": "authors", "collection_id": "aar94-yj226", "cite_using_url": "https://resolver.caltech.edu/CaltechAUTHORS:20120418-094841511", "type": "article", "title": "X-Ray Observations of the New Unusual Magnetar Swift J1834.9-0846", "author": [ { "family_name": "Kargaltsev", "given_name": "Oleg", "clpid": "Kargaltsev-O" }, { "family_name": "Kouveliotou", "given_name": "Chryssa", "orcid": "0000-0003-1443-593X", "clpid": "Kouveliotou-C" }, { "family_name": "Pavlov", "given_name": "George G.", "clpid": "Pavlov-G-G" }, { "family_name": "G\u00f6\u011f\u00fc\u015f", "given_name": "Ersin", "orcid": "0000-0002-5274-6790", "clpid": "G\u00f6\u011f\u00fc\u015f-E" }, { "family_name": "Lin", "given_name": "Lin", "orcid": "0000-0001-6860-9566", "clpid": "Lin-Lin" }, { "family_name": "Wachter", "given_name": "Stefanie", "clpid": "Wachter-Stefanie" }, { "family_name": "Griffith", "given_name": "Roger L.", "clpid": "Griffith-R-L" }, { "family_name": "Kaneko", "given_name": "Yuki", "orcid": "0000-0003-2342-0131", "clpid": "Kaneko-Yoshihiro" }, { "family_name": "Younes", "given_name": "George", "orcid": "0000-0002-7991-028X", "clpid": "Younes-G" } ], "abstract": "We present X-ray observations of the new transient magnetar Swift J1834.9\u20130846, discovered with the Swift Burst Alert Telescope on 2011 August 7. The data were obtained with Swift, Rossi X-ray Timing Explorer (RXTE), CXO, and XMM-Newton both before and after the outburst. Timing analysis reveals single peak pulsations with a period of 2.4823 s and an unusually high pulsed fraction, 85% \u00b1 10%. Using the RXTE and CXO data, we estimated the period derivative, \u1e56=8 x 10^(-12) s s^(\u20131), and confirmed the high magnetic field of the source, B = 1.4 \u00d7 10^(14)G. The decay of the persistent X-ray flux, spanning 48 days, is consistent with a power law, F \u03b1 t^(\u20130.5). In the CXO/Advanced CCD Imaging Spectrometer image, we find that the highly absorbed point source is surrounded by extended emission, which most likely is a dust scattering halo. Swift J1834.9\u20130846 is located near the center of the radio supernova remnant W41 and TeV source HESS J1834\u2013087. An association with W41 would imply a source distance of about 4 kpc; however, any relation to the HESS source remains unclear, given the presence of several other candidate counterparts for the latter source in the field. Our search for an IR counterpart of Swift J1834.9\u20130846 revealed no source down to K_s ~ 19.5 within the 0.\"6 CXO error circle.", "doi": "10.1088/0004-637X/748/1/26", "issn": "0004-637X", "publisher": "American Astronomical Society", "publication": "Astrophysical Journal", "publication_date": "2012-03-20", "series_number": "1", "volume": "748", "issue": "1", "pages": "Art. No. 26" }, { "id": "authors:s1z0e-d9f12", "collection": "authors", "collection_id": "s1z0e-d9f12", "cite_using_url": "https://resolver.caltech.edu/CaltechAUTHORS:20111007-100513883", "type": "article", "title": "Fermi/Gamma-Ray Burst Monitor Observations of SGR J0501+4516 Bursts", "author": [ { "family_name": "Lin", "given_name": "Lin", "orcid": "0000-0001-6860-9566", "clpid": "Lin-Lin" }, { "family_name": "Wachter", "given_name": "Stefanie", "clpid": "Wachter-Stefanie" } ], "abstract": "We present our temporal and spectral analyses of 29 bursts from SGR J0501+4516, detected with the gamma-ray burst monitor on board the Fermi Gamma-ray Space Telescope during 13 days of the source's activation in 2008 (August 22- September 3). We find that the T_90 durations of the bursts can be fit with a log-normal distribution with a mean value of ~123 ms. We also estimate for the first time event durations of soft gamma repeater (SGR) bursts in photon space (i.e., using their deconvolved spectra) and find that these are very similar to the T 90 values estimated in count space (following a log-normal distribution with a mean value of ~124 ms). We fit the time-integrated spectra for each burst and the time-resolved spectra of the five brightest bursts with several models. We find that a single power law with an exponential cutoff model fits all 29 bursts well, while 18 of the events can also be fit with two blackbody functions. We expand on the physical interpretation of these two models and we compare their parameters and discuss their evolution. We show that the time-integrated and time-resolved spectra reveal that E_peak decreases with energy flux (and fluence) to a minimum of ~30 keV at F = 8.7 \u00d7 10^(\u20136) erg cm^(\u20132) s^(\u20131), increasing steadily afterward. Two more sources exhibit a similar trend: SGRs J1550-5418 and 1806-20. The isotropic luminosity, L iso, corresponding to these flux values is roughly similar for all sources (0.4-1.5 \u00d7 10^(40) erg s^(\u20131)).", "doi": "10.1088/0004-637X/739/2/87", "issn": "0004-637X", "publisher": "American Astronomical Society", "publication": "Astrophysical Journal", "publication_date": "2011-10-01", "series_number": "2", "volume": "739", "issue": "2", "pages": "Art. No. 87" }, { "id": "authors:2f3e3-wjh52", "collection": "authors", "collection_id": "2f3e3-wjh52", "cite_using_url": "https://resolver.caltech.edu/CaltechAUTHORS:20091109-151802988", "type": "article", "title": "The All-Wavelength Extended Groth Strip International Survey (AEGIS) Data Sets", "author": [ { "family_name": "Davis", "given_name": "M.", "clpid": "Davis-M-E-Astro" }, { "family_name": "Guhathakurta", "given_name": "P.", "orcid": "0000-0001-8867-4234", "clpid": "Guhathakurta-P" }, { "family_name": "Konidaris", "given_name": "N. P.", "orcid": "0000-0003-1905-2815", "clpid": "Konidaris-N-P" }, { "family_name": "Newman", "given_name": "J. A.", "orcid": "0000-0001-8684-2222", "clpid": "Newman-J-A" }, { "family_name": "Ashby", "given_name": "M. L. N.", "orcid": "0000-0002-3993-0745", "clpid": "Ashby-M-L-N" }, { "family_name": "Biggs", "given_name": "A. D.", "orcid": "0000-0002-1117-9961", "clpid": "Biggs-A-D" }, { "family_name": "Barmby", "given_name": "P.", "orcid": "0000-0003-2767-0090", "clpid": "Barmby-P" }, { "family_name": "Bundy", "given_name": "K.", "orcid": "0000-0001-9742-3138", "clpid": "Bundy-K-A" }, { "family_name": "Chapman", "given_name": "S. C.", "clpid": "Chapman-S-C" }, { "family_name": "Coil", "given_name": "A. L.", "clpid": "Coil-A-L" }, { "family_name": "Conselice", "given_name": "C. J.", "orcid": "0000-0003-1949-7638", "clpid": "Conselice-C-J" }, { "family_name": "Cooper", "given_name": "M. C.", "orcid": "0000-0003-1371-6019", "clpid": "Cooper-M-C" }, { "family_name": "Croton", "given_name": "D. J.", "orcid": "0000-0002-5009-512X", "clpid": "Croton-D-J" }, { "family_name": "Eisenhardt", "given_name": "P. R. M.", "clpid": "Eisenhardt-P-R-M" }, { "family_name": "Ellis", "given_name": "R. S.", "orcid": "0000-0001-7782-7071", "clpid": "Ellis-R-S" }, { "family_name": "Faber", "given_name": "S. M.", "orcid": "0000-0003-4996-214X", "clpid": "Faber-S-M" }, { "family_name": "Fang", "given_name": "T.", "clpid": "Fang-T" }, { "family_name": "Fazio", "given_name": "G. G.", "orcid": "0000-0002-0670-0708", "clpid": "Fazio-G-G" }, { "family_name": "Georgakakis", "given_name": "A.", "clpid": "Georgakakis-A" }, { "family_name": "Gerke", "given_name": "B. F.", "clpid": "Gerke-B-F" }, { "family_name": "Goss", "given_name": "W. M.", "clpid": "Goss-W-M" }, { "family_name": "Gwyn", "given_name": "S.", "orcid": "0000-0001-8221-8406", "clpid": "Gwyn-S-D-J" }, { "family_name": "Harker", "given_name": "J.", "clpid": "Harker-J" }, { "family_name": "Hopkins", "given_name": "A. M.", "orcid": "0000-0002-6097-2747", "clpid": "Hopkins-A-M" }, { "family_name": "Huang", "given_name": "J.-S.", "clpid": "Huang-J-S" }, { "family_name": "Ivison", "given_name": "R. J.", "orcid": "0000-0001-5118-1313", "clpid": "Ivison-R-J" }, { "family_name": "Kassin", "given_name": "S. A.", "clpid": "Kassin-S-A" }, { "family_name": "Kirby", "given_name": "E. N.", "orcid": "0000-0001-6196-5162", "clpid": "Kirby-E-N" }, { "family_name": "Koekemoer", "given_name": "A. M.", "orcid": "0000-0002-6610-2048", "clpid": "Koekemoer-A-M" }, { "family_name": "Koo", "given_name": "D. C.", "orcid": "0000-0003-3385-6799", "clpid": "Koo-David-C" }, { "family_name": "Laird", "given_name": "E. S.", "clpid": "Laird-E-S" }, { "family_name": "Le Floc'h", "given_name": "E.", "clpid": "Le-Floc'h-Emeric" }, { "family_name": "Lin", "given_name": "L.", "orcid": "0000-0001-6860-9566", "clpid": "Lin-Lin" }, { "family_name": "Lotz", "given_name": "J. M.", "orcid": "0000-0003-3130-5643", "clpid": "Lotz-J-M" }, { "family_name": "Marshall", "given_name": "P. J.", "clpid": "Marshall-P-J" }, { "family_name": "Martin", "given_name": "D. C.", "orcid": "0000-0002-8650-1644", "clpid": "Martin-D-Christopher" }, { "family_name": "Metevier", "given_name": "A. J.", "clpid": "Metevier-A-J" }, { "family_name": "Moustakas", "given_name": "L. A.", "orcid": "0000-0003-3030-2360", "clpid": "Moustakas-L-A" }, { "family_name": "Nandra", "given_name": "K.", "orcid": "0000-0002-7150-9192", "clpid": "Nandra-K" }, { "family_name": "Noeske", "given_name": "K. G.", "clpid": "Noeske-K-G" }, { "family_name": "Papovich", "given_name": "C.", "orcid": "0000-0001-7503-8482", "clpid": "Papovich-C" }, { "family_name": "Phillips", "given_name": "A. C.", "clpid": "Phillips-A-C" }, { "family_name": "Rich", "given_name": "R. M.", "orcid": "0000-0003-0427-8387", "clpid": "Rich-R-M" }, { "family_name": "Rieke", "given_name": "G. H.", "orcid": "0000-0003-2303-6519", "clpid": "Rieke-G-H" }, { "family_name": "Rigopoulou", "given_name": "D.", "orcid": "0000-0001-6854-7545", "clpid": "Rigopoulou-D" }, { "family_name": "Salim", "given_name": "S.", "orcid": "0000-0003-2342-7501", "clpid": "Salim-S" }, { "family_name": "Schiminovich", "given_name": "D.", "clpid": "Schiminovich-D" }, { "family_name": "Simard", "given_name": "L.", "clpid": "Simard-L" }, { "family_name": "Smail", "given_name": "I.", "orcid": "0000-0003-3037-257X", "clpid": "Smail-Ian-R" }, { "family_name": "Small", "given_name": "T. A.", "clpid": "Small-T-A" }, { "family_name": "Weiner", "given_name": "B. J.", "clpid": "Weiner-B-J" }, { "family_name": "Willmer", "given_name": "C. N. A.", "clpid": "Willmer-C-N-A" }, { "family_name": "Willner", "given_name": "S. P.", "orcid": "0000-0002-9895-5758", "clpid": "Willner-S-P" }, { "family_name": "Wilson", "given_name": "G.", "orcid": "0000-0002-6572-7089", "clpid": "Wilson-G-W" }, { "family_name": "Wright", "given_name": "E. L.", "orcid": "0000-0001-5058-1593", "clpid": "Wright-E-L" }, { "family_name": "Yan", "given_name": "R.", "clpid": "Yan-Renbin" } ], "abstract": "In this the first of a series of Letters, we present a panchromatic data set in the Extended Groth Strip region of the sky. Our survey, the All-Wavelength Extended Groth Strip International Survey (AEGIS), aims to study the physical properties and evolutionary processes of galaxies at z ~ 1. It includes the following deep, wide-field imaging data sets: Chandra/ACIS X-ray, GALEX ultraviolet, CFHT/MegaCam Legacy Survey optical, CFHT/CFH12K optical, Hubble Space Telescope/ACS optical and NICMOS near-infrared, Palomar/WIRC near-infrared, Spitzer/IRAC mid-infrared, Spitzer/MIPS far-infrared, and VLA radio continuum. In addition, this region of the sky has been targeted for extensive spectroscopy using the Deep Imaging Multi-Object Spectrograph (DEIMOS) on the Keck II 10 m telescope. Our survey is compared to other large multiwavelength surveys in terms of depth and sky coverage.", "doi": "10.1086/517931", "issn": "2041-8205", "publisher": "American Astronomical Society", "publication": "Astrophysical Journal Letters", "publication_date": "2007-05-01", "series_number": "1", "volume": "660", "issue": "1", "pages": "L1-L6" } ]