@article{https://authors.library.caltech.edu/records/f08sq-jmm29, title = "Interactive computational and experimental approaches improve the sensitivity of periplasmic binding protein-based nicotine biosensors for measurements in biofluids", journal = "Protein Engineering, Design and Selection", url = "https://authors.library.caltech.edu/records/f08sq-jmm29", id = "record", issn = "1741-0126", doi = "10.1093/protein/gzae003", volume = "37" } @article{https://authors.library.caltech.edu/records/ndqwz-kx867, title = "Antidepressants enter cells, organelles, and membranes", journal = "Neuropsychopharmacology", url = "https://authors.library.caltech.edu/records/ndqwz-kx867", id = "record", issn = "0893-133X", doi = "10.1038/s41386-023-01725-x" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20230622-889344000.3, title = "β2 nAChR Activation on VTA DA Neurons Is Sufficient for Nicotine Reinforcement in Rats", journal = "eNeuro", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230622-889344000.3", id = "record", issn = "2373-2822", doi = "10.1523/eneuro.0449-22.2023", volume = "10", pmcid = "PMC10216253" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20230512-807738000.3, title = "Selective Serotonin Reuptake Inhibitors within Cells: Temporal Resolution in Cytoplasm, Endoplasmic Reticulum, and Membrane", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230512-807738000.3", id = "record", issn = "0270-6474", doi = "10.1523/jneurosci.1519-22.2022", volume = "43", pmcid = "PMC10072302" } @other{https://resolver.caltech.edu/CaltechAUTHORS:20230316-182493000.35, title = "Interactive computational and experimental approaches improve the sensitivity of periplasmic binding protein-based nicotine biosensors for measurements in biofluids", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230316-182493000.35", id = "record", doi = "10.1101/2023.01.16.524298" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220909-232673000, title = "Characterization of Binding Site Interactions and Selectivity Principles in the α3β4 Nicotinic Acetylcholine Receptor", journal = "Journal of the American Chemical Society", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220909-232673000", id = "record", issn = "0002-7863", doi = "10.1021/jacs.2c06495", volume = "144" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220906-252586000, title = {How many SARS-CoV-2 "viroporins" are really ion channels?}, journal = "Communications Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220906-252586000", id = "record", issn = "2399-3642", doi = "10.1038/s42003-022-03669-2", volume = "5" } @other{https://resolver.caltech.edu/CaltechAUTHORS:20220812-829310000, title = "Selective Serotonin Reuptake Inhibitors Within Cells: Temporal Resolution in Cytoplasm, Endoplasmic Reticulum, and Membrane", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220812-829310000", id = "record", doi = "10.1101/2022.08.09.502705" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220228-619163000, title = "Three Mutations Convert the Selectivity of a Protein Sensor from Nicotinic Agonists to S-Methadone for Use in Cells, Organelles, and Biofluids", journal = "Journal of the American Chemical Society", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220228-619163000", id = "record", issn = "0002-7863", doi = "10.1021/jacs.2c02323", volume = "144", pmcid = "PMC9121368" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20211008-224629724, title = "Fluorescence activation mechanism and imaging of drug permeation with new sensors for smoking-cessation ligands", journal = "eLife", url = "https://resolver.caltech.edu/CaltechAUTHORS:20211008-224629724", id = "record", issn = "2050-084X", doi = "10.7554/eLife.74648", volume = "11", pmcid = "PMC8820738" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20210820-224447031, title = "Protein profiling in the habenula after chronic (–)-menthol exposure in mice", journal = "Journal of Neurochemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210820-224447031", id = "record", issn = "0022-3042", doi = "10.1111/jnc.15495", volume = "158", pmcid = "PMC8577691" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20210714-140716932, title = "Regulation of epithelial sodium channel activity by SARS-CoV-1 and SARS-CoV-2 proteins", journal = "Biophysical Journal", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210714-140716932", id = "record", issn = "0006-3495", doi = "10.1016/j.bpj.2021.06.005", volume = "120", pmcid = "PMC8238646" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201217-143607354, title = "Directed Evolution of a Selective and Sensitive Serotonin Sensor via Machine Learning", journal = "Cell", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201217-143607354", id = "record", issn = "0092-8674", doi = "10.1016/j.cell.2020.11.040", volume = "183", pmcid = "PMC8025677" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201028-074338126, title = "Proteins for increased surface expression of the α6β4 nicotinic acetylcholine receptor: Nothing but good news?", journal = "Journal of Clinical Investigation", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201028-074338126", id = "record", issn = "0021-9738", doi = "10.1172/jci143197", volume = "130", pmcid = "PMC7598034" } @other{https://resolver.caltech.edu/CaltechAUTHORS:20200526-135356434, title = "Successful Cessation Programs that Reduce Comorbidity May Explain Surprisingly Low Smoking Rates Among Hospitalized COVID-19 Patients", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200526-135356434", id = "record", doi = "10.32388/WURFH0" } @other{https://resolver.caltech.edu/CaltechAUTHORS:20200210-132609996, title = "A fast genetically encoded fluorescent sensor for faithful in vivo acetylcholine detection in mice, fish, worms and flies", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200210-132609996", id = "record", doi = "10.1101/2020.02.07.939504" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200210-091504115, title = "Antagonists Pharmacologically Chaperone Opioid Receptors", journal = "Biophysical Journal", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200210-091504115", id = "record", issn = "0006-3495", doi = "10.1016/j.bpj.2019.11.328", volume = "118" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20191028-111942058, title = "Brain Region-Specific nAChR and Associated Protein Abundance Alterations Following Chronic Nicotine and/or Menthol Exposure", journal = "Journal of Proteome Research", url = "https://resolver.caltech.edu/CaltechAUTHORS:20191028-111942058", id = "record", issn = "1535-3893", doi = "10.1021/acs.jproteome.9b00286", volume = "19", pmcid = "PMC7289315" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20191218-090117543, title = "Biosensors Show the Pharmacokinetics of S-Ketamine in the Endoplasmic Reticulum", journal = "Frontiers in Cellular Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20191218-090117543", id = "record", issn = "1662-5102", doi = "10.3389/fncel.2019.00499", volume = "13", pmcid = "PMC6874132" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20191106-094121720, title = "Nicotine Bound to Its Receptors: New Structures for a Vexing Pathopharmacological Problem", journal = "Neuron", url = "https://resolver.caltech.edu/CaltechAUTHORS:20191106-094121720", id = "record", issn = "0896-6273", doi = "10.1016/j.neuron.2019.10.029", volume = "104" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20190916-135720189, title = "Probing Binding Interactions of Cytisine Derivatives to the α4β2 Nicotinic Acetylcholine Receptor", journal = "Journal of the American Chemical Society", url = "https://resolver.caltech.edu/CaltechAUTHORS:20190916-135720189", id = "record", issn = "0002-7863", doi = "10.1021/jacs.9b06580", volume = "141" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20190204-103658076, title = "Determining the pharmacokinetics of nicotinic drugs in the endoplasmic reticulum using biosensors", journal = "Journal of General Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20190204-103658076", id = "record", issn = "0022-1295", doi = "10.1085/jgp.201812201", volume = "151", pmcid = "PMC6571994" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20190128-151017476, title = "Chronic menthol does not change stoichiometry or functional plasma membrane levels of mouse α3β4-containing nicotinic acetylcholine receptors", journal = "Molecular Pharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20190128-151017476", id = "record", issn = "0026-895X", doi = "10.1124/mol.118.114769", volume = "95", pmcid = "PMC6399576" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20190123-075807331, title = "Bidirectional dopamine modulation of excitatory and inhibitory synaptic inputs to subthalamic neuron subsets containing α4β2 or α7 nAChRs", journal = "Neuropharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20190123-075807331", id = "record", issn = "0028-3908", doi = "10.1016/j.neuropharm.2019.01.015", volume = "148" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20190111-101254546, title = "Menthol stereoisomers exhibit different effects on α4β2 nAChR upregulation and dopamine neuron spontaneous firing", journal = "eNeuro", url = "https://resolver.caltech.edu/CaltechAUTHORS:20190111-101254546", id = "record", issn = "2373-2822", doi = "10.1523/eneuro.0465-18.2018", volume = "5", pmcid = "PMC6325563" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20180924-141114616, title = "α1-FANGs: Protein Ligands Selective for the α-Bungarotoxin Site of the α1-Nicotinic Acetylcholine Receptor", journal = "ACS Chemical Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180924-141114616", id = "record", issn = "1554-8929", doi = "10.1021/acschembio.8b00513", volume = "13", pmcid = "PMC8763392" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20180611-095839803, title = "Chronic nicotine improves cognitive and social impairment in mice overexpressing wild type α-synuclein", journal = "Neurobiology of Disease", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180611-095839803", id = "record", issn = "0969-9961", doi = "10.1016/j.nbd.2018.05.018", volume = "117", pmcid = "PMC6051902" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20180402-095419703, title = "Photoactivatable drugs for nicotinic optopharmacology", journal = "Nature Methods", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180402-095419703", id = "record", issn = "1548-7091", doi = "10.1038/nmeth.4637", volume = "15", pmcid = "PMC5923430" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20180523-150441864, title = {Microscopy Using Fluorescent Drug Biosensors for "Inside-Out Pharmacology"}, journal = "Biophysical Journal", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180523-150441864", id = "record", issn = "0006-3495", doi = "10.1016/j.bpj.2017.11.1990", volume = "114" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20180523-144402903, title = "Effects of Chronic Menthol at Alpha3Beta4 (α3β4)-Containing Nicotinic Acetylcholine Receptors", journal = "Biophysical Journal", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180523-144402903", id = "record", issn = "0006-3495", doi = "10.1016/j.bpj.2017.11.1691", volume = "114" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20171211-155148787, title = "Deletion of lynx1 reduces the function of α6* nicotinic receptors", journal = "PLoS ONE", url = "https://resolver.caltech.edu/CaltechAUTHORS:20171211-155148787", id = "record", issn = "1932-6203", doi = "10.1371/journal.pone.0188715", volume = "12", pmcid = "PMC5716591" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170418-150133796, title = "Menthol Enhances Nicotine Reward-Related Behavior by Potentiating Nicotine-Induced Changes in nAChR Function, nAChR Upregulation, and DA Neuron Excitability", journal = "Neuropsychopharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170418-150133796", id = "record", issn = "0893-133X", doi = "10.1038/npp.2017.72", volume = "42", pmcid = "PMC5645749" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20171113-110814227, title = "Acute Ethanol Administration Upregulates Synaptic α4-Subunit of Neuronal Nicotinic Acetylcholine Receptors within the Nucleus Accumbens and Amygdala", journal = "Frontiers in Molecular Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20171113-110814227", id = "record", issn = "1662-5099", doi = "10.3389/fnmol.2017.00338", volume = "10", pmcid = "PMC5660714" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170929-092012776, title = "Nicotine in the Endoplasmic Reticulum", journal = "Journal of General Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170929-092012776", id = "record", issn = "0022-1295", doi = "10.1085/jgp.149.9.889", volume = "149" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20171013-114018950, title = "TC299423, a Novel Agonist for Nicotinic Acetylcholine Receptors", journal = "Frontiers in Pharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20171013-114018950", id = "record", issn = "1663-9812", doi = "10.3389/fphar.2017.00641", volume = "8", pmcid = "PMC5626944" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170809-134755993, title = "Granulocytes as models for human protein marker identification following nicotine exposure", journal = "Journal of Neurochemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170809-134755993", id = "record", issn = "0022-3042", doi = "10.1111/jnc.14010", volume = "142", pmcid = "PMC6057152" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170724-083914067, title = "TRPV1 regulates excitatory innervation of OLM neurons in the hippocampus", journal = "Nature Communications", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170724-083914067", id = "record", issn = "2041-1723", doi = "10.1038/ncomms15878", volume = "8", pmcid = "PMC5524938" } @inbook{https://resolver.caltech.edu/CaltechAUTHORS:20170831-081004023, title = "Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XV", chapter = "Incubator embedded cell culture imaging system (EmSight) based on Fourier ptychographic microscopy", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170831-081004023", id = "record", isbn = "9781510605770", doi = "10.1117/12.2249906" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170314-072647704, title = "Probing for and Quantifying Agonist Hydrogen Bonds in α6β2 Nicotinic Acetylcholine Receptors", journal = "Biochemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170314-072647704", id = "record", issn = "0006-2960", doi = "10.1021/acs.biochem.7b00213", volume = "56", pmcid = "PMC6075822" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170921-153023998, title = "Region specific proteomic analysis of murine brain after chronic nicotine or menthol", journal = "FASEB Journal", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170921-153023998", id = "record", issn = "0892-6638", volume = "31" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170612-100040551, title = "Secondary Ammonium Agonists Make Dual Cation-π Interactions in α4β2 Nicotinic Receptors", journal = "eNeuro", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170612-100040551", id = "record", issn = "2373-2822", doi = "10.1523/ENEURO.0032-17.2017", volume = "4", pmcid = "PMC5458768" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170320-104204700, title = "Reliable Identification of Living Dopaminergic Neurons in Midbrain Cultures Using RNA Sequencing and TH-promoter-driven eGFP Expression", journal = "Journal of Visualized Experiments", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170320-104204700", id = "record", issn = "1940-087X", doi = "10.3791/54981", pmcid = "PMC5409190" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20160801-135931634, title = "Incubator embedded cell culture imaging system (EmSight) based on Fourier ptychographic microscopy", journal = "Biomedical Optics Express", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160801-135931634", id = "record", issn = "2156-7085", doi = "10.1364/BOE.7.003097", volume = "7", pmcid = "PMC4986817" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20160706-102113506, title = "Mutation Linked to Autosomal Dominant Nocturnal Frontal Lobe Epilepsy Reduces Low-Sensitivity α4β2, and Increases α5α4β2, Nicotinic Receptor Surface Expression", journal = "PLoS ONE", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160706-102113506", id = "record", issn = "1932-6203", doi = "10.1371/journal.pone.0158032", volume = "11", pmcid = "PMC4918917" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20160315-105822806, title = "Menthol Alone Upregulates Midbrain nAChRs, Alters nAChR Subtype Stoichiometry, Alters Dopamine Neuron Firing Frequency, and Prevents Nicotine Reward", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160315-105822806", id = "record", issn = "0270-6474", doi = "10.1523/JNEUROSCI.4194-15.2016", volume = "36", pmcid = "PMC4783498" } @other{https://resolver.caltech.edu/CaltechAUTHORS:20160414-084908996, title = "Probing binding interactions of agonists at a nicotinic acetylcholine receptor subtype important to addiction and Parkinson's disease", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160414-084908996", id = "record" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20160606-140109728, title = "Probing Binding Interactions of Agonists with the α6β2 Nicotinic Acetylcholine Receptor", journal = "Biophysical Journal", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160606-140109728", id = "record", issn = "0006-3495", doi = "10.1016/j.bpj.2015.11.3220", volume = "110" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20160606-140410523, title = "Effects of Menthol on α3β4∗ Nicotinic Receptors", journal = "Biophysical Journal", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160606-140410523", id = "record", issn = "0006-3495", doi = "10.1016/j.bpj.2015.11.3221", volume = "110" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20160111-082423100, title = "Smoking-Relevant Nicotine Concentration Attenuates the Unfolded Protein Response in Dopaminergic Neurons", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160111-082423100", id = "record", issn = "0270-6474", doi = "10.1523/JNEUROSCI.2126-15.2016", volume = "36", pmcid = "PMC4701966" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150728-082757273, title = "Ketamine Inside Neurons?", journal = "American Journal of Psychiatry", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150728-082757273", id = "record", issn = "0002-953X", doi = "10.1176/appi.ajp.2015.14121537", volume = "172", pmcid = "PMC6107348" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150429-110737552, title = "Heterologous expression and nonsense suppression provide insights into agonist behavior at α6β2 nicotinic acetylcholine receptors", journal = "Neuropharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150429-110737552", id = "record", issn = "0028-3908", doi = "10.1016/j.neuropharm.2015.04.009", volume = "97", pmcid = "PMC4635625" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150211-075813471, title = "Inside-out neuropharmacology of nicotinic drugs", journal = "Neuropharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150211-075813471", id = "record", issn = "0028-3908", doi = "10.1016/j.neuropharm.2015.01.022", volume = "96", pmcid = "PMC4486611" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150224-151714505, title = "The human CHRNA7 and CHRFAM7A genes: A review of the genetics, regulation, and function", journal = "Neuropharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150224-151714505", id = "record", issn = "0028-3908", doi = "10.1016/j.neuropharm.2015.02.006", volume = "96", pmcid = "PMC4486515" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150728-085848506, title = "An Unaltered Orthosteric Site and a Network of Long-Range Allosteric Interactions for PNU-120596 in α7 Nicotinic Acetylcholine Receptors", journal = "Chemistry and Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150728-085848506", id = "record", issn = "1074-5521", doi = "10.1016/j.chembiol.2015.06.018", volume = "22", pmcid = "PMC4547686" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150519-092649728, title = "The nicotinic α6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2/3 receptors", journal = "Science Translational Medicine", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150519-092649728", id = "record", issn = "1946-6234", doi = "10.1126/scitranslmed.3009986", volume = "7", pmcid = "PMC5018401" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150106-073218861, title = "Allosteric activation of the 5-HT\_3AB receptor by mCPBG", journal = "Neuropharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150106-073218861", id = "record", issn = "0028-3908", doi = "10.1016/j.neuropharm.2014.12.018", volume = "91", pmcid = "PMC4312754" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150309-153924379, title = "Nicotinic Receptor Subtype-Selective Circuit Patterns in the Subthalamic Nucleus", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150309-153924379", id = "record", issn = "0270-6474", doi = "10.1523/JNEUROSCI.3528-14.2015", volume = "35", pmcid = "PMC4348180" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20140915-092705574, title = "Lynx1 Shifts α4β2 Nicotinic Receptor Subunit Stoichiometry by Affecting Assembly in the Endoplasmic Reticulum", journal = "Journal of Biological Chemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140915-092705574", id = "record", issn = "0021-9258", doi = "10.1074/jbc.M114.573667", volume = "289", pmcid = "PMC4223341" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20140811-132238553, title = "Functional Evaluation of Key Interactions Evident in the Structure of the Eukaryotic Cys-Loop Receptor GluCl", journal = "ACS Chemical Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140811-132238553", id = "record", issn = "1554-8929", doi = "10.1021/cb500323d", volume = "9", pmcid = "PMC4201344" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20140729-082327052, title = "The duplicated α7 subunits assemble and form functional nicotinic receptors with the full-length α7", journal = "Journal of Biological Chemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140729-082327052", id = "record", issn = "0021-9258", doi = "10.1074/jbc.M114.582858", volume = "289", pmcid = "PMC4176222" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20141016-090934738, title = "Subtype-Specific Mechanisms for Functional Interaction between α6β4* Nicotinic Acetylcholine Receptors and P2X Receptors", journal = "Molecular Pharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20141016-090934738", id = "record", issn = "0026-895X", doi = "10.1124/mol.114.093179", volume = "86", pmcid = "PMC4152909" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20140721-090832827, title = "lynx1 Supports Neuronal Health in the Mouse Dorsal Striatum During Aging: an Ultrastructural Investigation", journal = "Journal of Molecular Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140721-090832827", id = "record", issn = "0895-8696", doi = "10.1007/s12031-014-0352-1", volume = "53", pmcid = "PMC4265479" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20140814-112513666, title = "Differential Expression and Function of Nicotinic Acetylcholine Receptors in Subdivisions of Medial Habenula", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140814-112513666", id = "record", issn = "0270-6474", doi = "10.1523/JNEUROSCI.0476-14.2014", volume = "34", pmcid = "PMC4099552" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170302-160217090, title = "Selective Ligand Behaviors Provide New Insights into Agonist Activation of Nicotinic Acetylcholine Receptors", journal = "ACS Chemical Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170302-160217090", id = "record", issn = "1554-8929", doi = "10.1021/cb400937d", volume = "9", pmcid = "PMC4033646" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20140724-150050094, title = "Pharmacological chaperoning of nAChRs: A therapeutic target for Parkinson's disease", journal = "Pharmacological Research", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140724-150050094", id = "record", issn = "1043-6618", doi = "10.1016/j.phrs.2014.02.005", volume = "83", pmcid = "PMC6075820" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150205-130837428, title = "Drugs and the brain, the MOOC", journal = "FASEB Journal", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150205-130837428", id = "record", issn = "0892-6638", volume = "28" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20140227-142503676, title = "Probing the non-canonical interface for agonist interaction with an α5 containing nicotinic acetylcholine receptor", journal = "Neuropharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140227-142503676", id = "record", issn = "0028-3908", doi = "10.1016/j.neuropharm.2013.09.028", volume = "77", pmcid = "PMC3934363" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20140710-095141475, title = "Structure Function Studies at Two Different Nicotinic Acetylcholine Receptor Subtypes", journal = "Biophysical Journal", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140710-095141475", id = "record", issn = "0006-3495", doi = "10.1016/j.bpj.2013.11.1950", volume = "106" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20140710-092155936, title = "Identifying Motifs Essential for Selective Activation of Nicotinic Acetylcholine Receptors", journal = "Biophysical Journal", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140710-092155936", id = "record", issn = "0006-3495", doi = "10.1016/j.bpj.2013.11.1951", volume = "106" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150108-114406249, title = "Drug Actions on Nicotinic Receptors. Chronic vs Acute; Outside-in vs Inside-out", journal = "Neuropsychopharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150108-114406249", id = "record", issn = "0893-133X", volume = "39" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20140123-151832351, title = "Nicotine exploits a COPI-mediated process for chaperone-mediated up-regulation of its receptors", journal = "Journal of General Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140123-151832351", id = "record", issn = "0022-1295", doi = "10.1085/jgp.201311102", volume = "143", pmcid = "PMC3874574" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20130815-073947290, title = "Transcriptional regulation by nicotine in dopaminergic neurons", journal = "Biochemical Pharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20130815-073947290", id = "record", issn = "0006-2952", doi = "10.1016/j.bcp.2013.07.031", volume = "86", pmcid = "PMC3969234" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20130912-145808068, title = "The 5-HT\_3AB Receptor Shows an A\_3B\_2 Stoichiometry at the Plasma Membrane", journal = "Biophysical Journal", url = "https://resolver.caltech.edu/CaltechAUTHORS:20130912-145808068", id = "record", issn = "0006-3495", doi = "10.1016/j.bpj.2013.07.015", volume = "105", pmcid = "PMC3752109" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20130808-161341375, title = "An Unusual Pattern of Ligand-Receptor Interactions for the α7 Nicotinic Acetylcholine Receptor, with Implications for the Binding of Varenicline", journal = "Molecular Pharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20130808-161341375", id = "record", issn = "0026-895X", doi = "10.1124/mol.113.085795", volume = "84", pmcid = "PMC3716316" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20130909-090111946, title = "An Engineered Glutamate-gated Chloride (GluCl) Channel for Sensitive, Consistent Neuronal Silencing by Ivermectin", journal = "Journal of Biological Chemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:20130909-090111946", id = "record", issn = "0021-9258", doi = "10.1074/jbc.M112.423921", volume = "288", pmcid = "PMC3774370" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20130909-105437251, title = "The α5 Subunit Regulates the Expression and Function of α4*-Containing Neuronal Nicotinic Acetylcholine Receptors in the Ventral-Tegmental Area", journal = "PLoS ONE", url = "https://resolver.caltech.edu/CaltechAUTHORS:20130909-105437251", id = "record", issn = "1932-6203", doi = "10.1371/journal.pone.0068300", volume = "8", pmcid = "PMC3712017" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20130411-103637479, title = "Binding Interactions with the Complementary Subunit of Nicotinic Receptors", journal = "Journal of Biological Chemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:20130411-103637479", id = "record", issn = "0021-9258", doi = "10.1074/jbc.M112.439968", volume = "288", pmcid = "PMC3591609" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20130328-101734866, title = "Key Binding Interactions for Memantine in the NMDA Receptor", journal = "ACS Chemical Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20130328-101734866", id = "record", issn = "1948-7193", doi = "10.1021/cn300180a", volume = "4", pmcid = "PMC3751542" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20130319-103616459, title = "Mice expressing the ADNFLE valine 287 leucine mutation of the Β2 nicotinic acetylcholine receptor subunit display increased sensitivity to acute nicotine administration and altered presynaptic nicotinic receptor function", journal = "Pharmacology Biochemistry and Behavior", url = "https://resolver.caltech.edu/CaltechAUTHORS:20130319-103616459", id = "record", issn = "0091-3057", doi = "10.1016/j.pbb.2012.10.014", volume = "103", pmcid = "PMC3544981" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20121217-074942263, title = "Psychiatric Drugs Bind to Classical Targets Within Early Exocytotic Pathways: Therapeutic Effects", journal = "Biological Psychiatry", url = "https://resolver.caltech.edu/CaltechAUTHORS:20121217-074942263", id = "record", issn = "0006-3223", doi = "10.1016/j.biopsych.2012.05.020", volume = "72", pmcid = "PMC6167061" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20121127-103848210, title = "A Coupled Array of Noncovalent Interactions Impacts the Function of the 5‑HT\_3A Serotonin Receptor in an Agonist-Specific Way", journal = "ACS Chemical Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20121127-103848210", id = "record", issn = "1948-7193", doi = "10.1021/cn3000586", volume = "3", pmcid = "PMC3474281" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20121217-082045717, title = "Variability of acute extracellular action potential measurements with multisite silicon probes", journal = "Journal of Neuroscience Methods", url = "https://resolver.caltech.edu/CaltechAUTHORS:20121217-082045717", id = "record", issn = "0165-0270", doi = "10.1016/j.jneumeth.2012.08.005", volume = "211", pmcid = "PMC3473102" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20121127-104931725, title = "Ondansetron and Granisetron Binding Orientation in the 5‑HT\_3 Receptor Determined by Unnatural Amino Acid Mutagenesis", journal = "ACS Chemical Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20121127-104931725", id = "record", issn = "1554-8929", doi = "10.1021/cb300246j", volume = "7", pmcid = "PMC3477246" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20121108-131347078, title = "Insights into the Neurobiology of the Nicotinic Cholinergic System and Nicotine Addiction from Mice Expressing Nicotinic Receptors Harboring Gain-of-Function Mutations", journal = "Pharmacological Reviews", url = "https://resolver.caltech.edu/CaltechAUTHORS:20121108-131347078", id = "record", issn = "0031-6997", doi = "10.1124/pr.111.004671", volume = "64", pmcid = "PMC3462994" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20121031-153603159, title = "Functionally Important Aromatic–Aromatic and Sulfur−π Interactions in the D2 Dopamine Receptor", journal = "Journal of the American Chemical Society", url = "https://resolver.caltech.edu/CaltechAUTHORS:20121031-153603159", id = "record", issn = "0002-7863", doi = "10.1021/ja304560x", volume = "134", pmcid = "PMC3461201" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120910-073630839, title = "Electrophysiological characterization of Grueneberg ganglion olfactory neurons: spontaneous firing, sodium conductance, and hyperpolarization-activated currents", journal = "Journal of Neurophysiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120910-073630839", id = "record", issn = "0022-3077", volume = "108", pmcid = "PMC3544954" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120926-114816752, title = "Unparalleled Control of Neural Activity Using Orthogonal Pharmacogenetics", journal = "ACS Chemical Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120926-114816752", id = "record", issn = "1948-7193", doi = "10.1021/cn300053q", volume = "3", pmcid = "PMC3419455" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120924-131621260, title = "Optimizing Cholinergic Tone Through Lynx Modulators of Nicotinic Receptors: Implications for Plasticity and Nicotine Addiction", journal = "Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120924-131621260", id = "record", issn = "1548-9221", doi = "10.1152/physiol.00002.2012", volume = "27" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120907-141513430, title = "Förster Resonance Energy Transfer (FRET) Correlates of Altered Subunit Stoichiometry in Cys-Loop Receptors, Exemplified by Nicotinic α4β2", journal = "International Journal of Molecular Sciences", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120907-141513430", id = "record", issn = "1422-0067", doi = "10.3390/ijms130810022", volume = "13", pmcid = "PMC3431844" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120904-085001085, title = "α6* Nicotinic Acetylcholine Receptor Expression and Function in a Visual Salience Circuit", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120904-085001085", id = "record", issn = "0270-6474", doi = "10.1523/JNEUROSCI.0007-12.2012", volume = "32", pmcid = "PMC3432940" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120824-131040943, title = "Variations in Binding Among Several Agonists at Two Stoichiometries of the Neuronal, α4β2 Nicotinic Receptor", journal = "Journal of the American Chemical Society", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120824-131040943", id = "record", issn = "0002-7863", doi = "10.1021/ja3011379", volume = "134", pmcid = "PMC3399941" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120813-111734004, title = "Live-Cell Imaging of Single Receptor Composition Using Zero-Mode Waveguide Nanostructures", journal = "Nano Letters", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120813-111734004", id = "record", issn = "1530-6984", doi = "10.1021/nl301480h", volume = "12", pmcid = "PMC3397148" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120613-133532352, title = "Probing the Effects of Residues Located Outside the Agonist Binding Site on Drug-Receptor Selectivity in the Nicotinic Receptor", journal = "ACS Chemical Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120613-133532352", id = "record", issn = "1554-8929", doi = "10.1021/cb200448j", volume = "7", pmcid = "PMC3356501" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120530-081520292, title = "Pharmacological Chaperoning of Nicotinic Acetylcholine Receptors Reduces the Endoplasmic Reticulum Stress Response", journal = "Molecular Pharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120530-081520292", id = "record", issn = "0026-895X", doi = "10.1124/mol.112.077792", volume = "81", pmcid = "PMC3362896" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120214-145000544, title = "α7β2 Nicotinic Acetylcholine Receptors Assemble, Function, and Are Activated Primarily via Their α7-α7 Interfaces", journal = "Molecular Pharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120214-145000544", id = "record", issn = "0026-895X", doi = "10.1124/mol.111.074088", volume = "81", pmcid = "PMC3263954" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120214-082915834, title = "Nicotinic cholinergic mechanisms causing elevated dopamine release and abnormal locomotor behavior", journal = "Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120214-082915834", id = "record", issn = "0306-4522", doi = "10.1016/j.neuroscience.2011.10.047", volume = "200", pmcid = "PMC3249511" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20110922-073823540, title = "Characterizing functional α6β2 nicotinic acetylcholine receptors in vitro: Mutant β2 subunits improve membrane expression, and fluorescent proteins reveal responsive cells", journal = "Biochemical Pharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20110922-073823540", id = "record", issn = "0006-2952", doi = "10.1016/j.bcp.2011.05.005", volume = "82", pmcid = "PMC3162078" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20111111-102216534, title = "Multiplexed, High Density Electrophysiology with Nanofabricated Neural Probes", journal = "PLoS ONE", url = "https://resolver.caltech.edu/CaltechAUTHORS:20111111-102216534", id = "record", issn = "1932-6203", doi = "10.1371/journal.pone.0026204", volume = "6", pmcid = "PMC3192171" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20111028-122557103, title = "Varenicline Is a Potent Agonist of the Human 5-Hydroxytryptamine\_3 Receptor", journal = "Journal of Pharmacology and Experimental Therapeutics", url = "https://resolver.caltech.edu/CaltechAUTHORS:20111028-122557103", id = "record", issn = "0022-3565", doi = "10.1124/jpet.111.185306", volume = "339", pmcid = "PMC3186289" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20111018-104112346, title = "Altered activity–rest patterns in mice with a human autosomal-dominant nocturnal frontal lobe epilepsy mutation in the β2 nicotinic receptor", journal = "Molecular Psychiatry", url = "https://resolver.caltech.edu/CaltechAUTHORS:20111018-104112346", id = "record", issn = "1359-4184", doi = "10.1038/mp.2010.78", volume = "16", pmcid = "PMC2970689" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20111116-105837023, title = "Dissecting the Functions of Conserved Prolines within Transmembrane Helices of the D2 Dopamine Receptor", journal = "ACS Chemical Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20111116-105837023", id = "record", issn = "1554-8929", doi = "10.1021/cb200153g", volume = "6", pmcid = "PMC3199346" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20111004-120511603, title = "Evidence for an Extended Hydrogen Bond Network in the Binding Site of the Nicotinic Receptor: Role of the Vicinal Disulfide of the α1 Subunit", journal = "Journal of Biological Chemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:20111004-120511603", id = "record", issn = "0021-9258", doi = "10.1074/jbc.M111.254235", volume = "286", pmcid = "PMC3173184" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20110922-112958690, title = "Trafficking of α4^* Nicotinic Receptors Revealed by Superecliptic Phluorin", journal = "Journal of Biological Chemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:20110922-112958690", id = "record", issn = "0021-9258", doi = "10.1074/jbc.M111.256024", volume = "286", pmcid = "PMC3173132" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20110502-112328466, title = "Two Neuronal Nicotinic Acetylcholine Receptors, α4β4 and α7, Show Differential Agonist Binding Modes", journal = "Journal of Biological Chemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:20110502-112328466", id = "record", issn = "0021-9258", doi = "10.1074/jbc.M110.206565", volume = "286", pmcid = "PMC3077659" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20110519-095350891, title = "Neural Systems Governed by Nicotinic Acetylcholine Receptors: Emerging Hypotheses", journal = "Neuron", url = "https://resolver.caltech.edu/CaltechAUTHORS:20110519-095350891", id = "record", issn = "0896-6273", doi = "10.1016/j.neuron.2011.03.014", volume = "70", pmcid = "PMC4418790" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20110404-100247422, title = "A Cation-π Interaction at a Phenylalanine Residue in the Glycine Receptor Binding Site Is Conserved for Different Agonists", journal = "Molecular Pharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20110404-100247422", id = "record", issn = "0026-895X", doi = "10.1124/mol.110.069583", volume = "79", pmcid = "PMC3063724" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20110208-094115987, title = "Nicotine up-regulates α4β2 nicotinic receptors and ER exit sites via stoichiometry-dependent chaperoning", journal = "Journal of General Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20110208-094115987", id = "record", issn = "0022-1295", doi = "10.1085/jgp.201010532", volume = "137", pmcid = "PMC3010053" } @inbook{https://resolver.caltech.edu/CaltechAUTHORS:20111114-081228635, title = "Allostery: Methods and Protocols", chapter = "Using Mutant Cycle Analysis to Elucidate Long-Range Functional Coupling in Allosteric Receptors", url = "https://resolver.caltech.edu/CaltechAUTHORS:20111114-081228635", id = "record", isbn = "9781617793332", doi = "10.1007/978-1-61779-334-9\_6", pmcid = "PMC4006985" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20101221-093346658, title = "The structural basis of function in Cys-loop receptors", journal = "Quarterly Reviews of Biophysics", url = "https://resolver.caltech.edu/CaltechAUTHORS:20101221-093346658", id = "record", issn = "0033-5835", doi = "10.1017/S0033583510000168", volume = "43" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20100913-091409908, title = "Nicotinic pharmacophore: The pyridine N of nicotine and carbonyl of acetylcholine hydrogen bond across a subunit interface to a backbone NH", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:20100913-091409908", id = "record", issn = "0027-8424", doi = "10.1073/pnas.1007140107", volume = "107", pmcid = "PMC2922130" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20100811-085614377, title = "Cholinergic Modulation of Locomotion and Striatal Dopamine Release Is Mediated by α6α4* Nicotinic Acetylcholine Receptors", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20100811-085614377", id = "record", issn = "0270-6474", doi = "10.1523/JNEUROSCI.2056-10.2010", volume = "30", pmcid = "PMC3390922" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20100709-141019159, title = "Photochemical Proteolysis of an Unstructured Linker of the GABAAR Extracellular Domain Prevents GABA but Not Pentobarbital Activation", journal = "Molecular Pharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20100709-141019159", id = "record", issn = "0026-895X", doi = "10.1124/mol.109.059832", volume = "78", pmcid = "PMC2912059" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20100604-114525877, title = "Structural differences determine the relative selectivity of nicotinic compounds for native α4β2^*-, α6β2^*-, α3β4^*- and α7-nicotine acetylcholine receptors", journal = "Neuropharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20100604-114525877", id = "record", issn = "0028-3908", doi = "10.1016/j.neuropharm.2010.01.013", volume = "58", pmcid = "PMC2849849" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20100409-120603576, title = "Chemical Scale Studies of the Phe-Pro Conserved Motif in the Cys Loop of Cys", journal = "Journal of Biological Chemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:20100409-120603576", id = "record", issn = "0021-9258", doi = "10.1074/jbc.M109.060939", volume = "285", pmcid = "PMC2838319" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20100119-103312477, title = "Dopamine D\_2-receptor activation elicits akinesia, rigidity, catalepsy, and tremor in mice expressing hypersensitive 4 nicotinic receptors via a cholinergic-dependent mechanism", journal = "FASEB Journal", url = "https://resolver.caltech.edu/CaltechAUTHORS:20100119-103312477", id = "record", issn = "0892-6638", doi = "10.1096/fj.09-137034", volume = "24", pmcid = "PMC2797035" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20091218-122259894, title = "GABA transporter function, oligomerization state, and anchoring: correlates with subcellularly resolved FRET", journal = "Journal of General Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20091218-122259894", id = "record", issn = "0022-1295", doi = "10.1085/jgp.200910314", volume = "134", pmcid = "PMC2806419" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20091102-100009481, title = "Chronic Nicotine Selectively Enhances α4β2* Nicotinic Acetylcholine Receptors in the Nigrostriatal Dopamine Pathway", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20091102-100009481", id = "record", issn = "0270-6474", doi = "10.1523/JNEUROSCI.2939-09.2009", volume = "29", pmcid = "PMC2787412" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20090916-091123236, title = "Pharmacological chaperoning of nicotinic receptors begins in the endoplasmic reticulum: High-resolution imaging", journal = "Biochemical Pharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20090916-091123236", id = "record", issn = "0006-2952", doi = "10.1016/j.bcp.2009.06.033", volume = "78" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20090911-153603948, title = "Pharmacological chaperoning of nicotinic receptors begins in the endoplasmic reticulum: Compartments and stoichiometries", journal = "Biochemical Pharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20090911-153603948", id = "record", issn = "0006-2952", doi = "10.1016/j.bcp.2009.06.032", volume = "78" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20090730-103918926, title = "Evaluation of structurally diverse neuronal nicotinic receptor ligands for selectivity at the α6 subtype", journal = "Bioorganic and Medicinal Chemistry Letters", url = "https://resolver.caltech.edu/CaltechAUTHORS:20090730-103918926", id = "record", issn = "0960-894X", doi = "10.1016/j.bmcl.2009.05.085", volume = "19", pmcid = "PMC6107347" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20090901-141204665, title = "Probing the role of the cation–π interaction in the binding sites of GPCRs using unnatural amino acids", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:20090901-141204665", id = "record", issn = "0027-8424", doi = "10.1073/pnas.0903260106", volume = "106", pmcid = "PMC2715518" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20090805-085419387, title = "Probing the role of backbone hydrogen bonding in a critical β sheet of the extracellular domain of a cys-loop receptor", journal = "ChemBioChem", url = "https://resolver.caltech.edu/CaltechAUTHORS:20090805-085419387", id = "record", issn = "1439-4227", doi = "10.1002/cbic.200900092", volume = "10", pmcid = "PMC2789490" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20090914-084414850, title = "Nicotine Normalizes Intracellular Subunit Stoichiometry of Nicotinic Receptors Carrying Mutations Linked to Autosomal Dominant Nocturnal Frontal Lobe Epilepsy", journal = "Molecular Pharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20090914-084414850", id = "record", issn = "0026-895X", doi = "10.1124/mol.108.054494", volume = "75", pmcid = "PMC2672806" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20090827-132541833, title = "Long-Range Coupling in an Allosteric Receptor Revealed by Mutant Cycle Analysis", journal = "Biophysical Journal", url = "https://resolver.caltech.edu/CaltechAUTHORS:20090827-132541833", id = "record", issn = "0006-3495", doi = "10.1016/j.bpj.2008.12.3949", volume = "96", pmcid = "PMC2718292" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20090903-090332845, title = "Ezrin Mediates Tethering of the γ-Aminobutyric Acid Transporter GAT1 to Actin Filaments Via a C-Terminal PDZ-Interacting Domain", journal = "Biophysical Journal", url = "https://resolver.caltech.edu/CaltechAUTHORS:20090903-090332845", id = "record", issn = "0006-3495", doi = "10.1016/j.bpj.2008.11.070", volume = "96", pmcid = "PMC2711277" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20090422-090708342, title = "Nicotine binding to brain receptors requires a strong cation–π interaction", journal = "Nature", url = "https://resolver.caltech.edu/CaltechAUTHORS:20090422-090708342", id = "record", issn = "0028-0836", doi = "10.1038/nature07768", volume = "458", pmcid = "PMC2755585" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20090707-084125313, title = "Nicotine is a Selective Pharmacological Chaperone of Acetylcholine Receptor Number and Stoichiometry. Implications for Drug Discovery", journal = "AAPS Journal", url = "https://resolver.caltech.edu/CaltechAUTHORS:20090707-084125313", id = "record", issn = "1550-7416", doi = "10.1208/s12248-009-9090-7", volume = "11", pmcid = "PMC2664890" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20090717-142050047, title = "A proposal for a coordinated effort for the determination of brainwide neuroanatomical connectivity in model organisms at a mesoscopic scale", journal = "PLoS Computational Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20090717-142050047", id = "record", issn = "1553-734X", doi = "10.1371/journal.pcbi.1000334", volume = "5", pmcid = "PMC2655718" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20090909-105237809, title = "Single-Molecule Imaging of a Fluorescent Unnatural Amino Acid Incorporated Into Nicotinic Receptors", journal = "Biophysical Journal", url = "https://resolver.caltech.edu/CaltechAUTHORS:20090909-105237809", id = "record", issn = "0006-3495", doi = "10.1016/j.bpj.2008.09.034", volume = "96", pmcid = "PMC2710013" } @article{https://resolver.caltech.edu/CaltechAUTHORS:GLEjbc08, title = "An intersubunit hydrogen bond in the nicotinic acetylcholine receptor that contributes to channel gating", journal = "Journal of Biological Chemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:GLEjbc08", id = "record", issn = "0021-9258", doi = "10.1074/jbc.M807226200", volume = "283", pmcid = "PMC2602911" } @article{https://resolver.caltech.edu/CaltechAUTHORS:PLEjns08, title = "A Cation-π Interaction in the Binding Site of the Glycine Receptor Is Mediated by a Phenylalanine Residue", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:PLEjns08", id = "record", issn = "0270-6474", doi = "10.1523/JNEUROSCI.2540-08.2008", volume = "28", pmcid = "PMC2649377" } @article{https://resolver.caltech.edu/CaltechAUTHORS:DREn08, title = "In vivo activation of midbrain dopamine neurons via sensitized, high-affinity α6*nicotinic acetylcholine receptors", journal = "Neuron", url = "https://resolver.caltech.edu/CaltechAUTHORS:DREn08", id = "record", issn = "0896-6273", doi = "10.1016/j.neuron.2008.09.009", volume = "60", pmcid = "PMC2632732" } @article{https://resolver.caltech.edu/CaltechAUTHORS:HANjacs08, title = "A Stereochemical Test of a Proposed Structural Feature of the Nicotinic Acetylcholine Receptor", journal = "Journal of the American Chemical Society", url = "https://resolver.caltech.edu/CaltechAUTHORS:HANjacs08", id = "record", issn = "0002-7863", doi = "10.1021/ja8015457", volume = "130" } @article{https://resolver.caltech.edu/CaltechAUTHORS:FONnp09, title = "Demonstration of functional α4-containing nicotinic receptors in the medial habenula", journal = "Neuropharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:FONnp09", id = "record", issn = "0028-3908", doi = "10.1016/j.neuropharm.2008.08.021", volume = "56", pmcid = "PMC2645341" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170201-090914461, title = "A Hydrogen Bond in Loop A Is Critical for the Binding and Function of the 5-HT\_3 Receptor", journal = "Biochemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170201-090914461", id = "record", issn = "0006-2960", doi = "10.1021/bi800222n", volume = "47", pmcid = "PMC264937" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170409-064941478, title = "Confirming the Revised C-Terminal Domain of the MscL Crystal Structure", journal = "Biophysical Journal", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170409-064941478", id = "record", issn = "0006-3495", doi = "10.1529/biophysj.107.127365", volume = "94", pmcid = "PMC2397327" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200421-112849285, title = "α4* Nicotinic Receptors in preBotzinger Complex Mediate Cholinergic/Nicotinic Modulation of Respiratory Rhythm", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200421-112849285", id = "record", issn = "0270-6474", doi = "10.1523/jneurosci.3666-07.2008", volume = "28", pmcid = "PMC3477875" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200422-074016834, title = "Subcellular Trafficking, Pentameric Assembly, and Subunit Stoichiometry of Neuronal Nicotinic Acetylcholine Receptors Containing Fluorescently Labeled α6 and β3 Subunits", journal = "Molecular Pharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200422-074016834", id = "record", issn = "0026-895X", doi = "10.1124/mol.107.039180", volume = "73" } @article{https://resolver.caltech.edu/CaltechAUTHORS:PLEjbc07, title = "Conformational variability of the glycine receptor M2 domain in response to activation by different agonists", journal = "Journal of Biological Chemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:PLEjbc07", id = "record", issn = "0021-9258", doi = "10.1074/jbc.M706468200", volume = "282" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200424-071823168, title = "Nicotine responses in hypersensitive and knockout α4 mice account for tolerance to both hypothermia and locomotor suppression in wild-type mice", journal = "Physiological Genomics", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200424-071823168", id = "record", issn = "1094-8341", doi = "10.1152/physiolgenomics.00063.2007", volume = "31" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200415-144744313, title = "Improved amber and opal suppressor tRNAs for incorporation of unnatural amino acids in vivo. Part 2: Evaluating suppression efficiency", journal = "RNA", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200415-144744313", id = "record", issn = "1355-8382", doi = "10.1261/rna.667607", volume = "13", pmcid = "PMC1986817" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200415-144146916, title = "Improved amber and opal suppressor tRNAs for incorporation of unnatural amino acids in vivo. Part 1: Minimizing misacylation", journal = "RNA", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200415-144146916", id = "record", issn = "1355-8382", doi = "10.1261/rna.666807", volume = "13", pmcid = "PMC1986802" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200422-080631596, title = "Nicotine-Induced Dystonic Arousal Complex in a Mouse Line Harboring a Human Autosomal-Dominant Nocturnal Frontal Lobe Epilepsy Mutation", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200422-080631596", id = "record", issn = "0270-6474", doi = "10.1523/jneurosci.3042-07.2007", volume = "27", pmcid = "PMC6672658" } @article{https://resolver.caltech.edu/CaltechAUTHORS:WANjbc07, title = "Establishing an Ion Pair Interaction in the Homomeric {rho}1 {gamma}-Aminobutyric Acid Type A Receptor That Contributes to the Gating Pathway", journal = "Journal of Biological Chemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:WANjbc07", id = "record", issn = "0021-9258", doi = "10.1074/jbc.M702314200", volume = "282" } @article{https://resolver.caltech.edu/CaltechAUTHORS:JANjbc07, title = "Rodent Aβ Modulates the Solubility and Distribution of Amyloid Deposits in Transgenic Mice", journal = "Journal of Biological Chemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:JANjbc07", id = "record", issn = "0021-9258", doi = "10.1074/jbc.M611050200", volume = "282", pmcid = "PMC4435736" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20190905-080227761, title = "Chronic Nicotine Cell Specifically Upregulates Functional α4* Nicotinic Receptors: Basis for Both Tolerance in Midbrain and Enhanced Long-Term Potentiation in Perforant Path", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20190905-080227761", id = "record", issn = "0270-6474", doi = "10.1523/jneurosci.2199-07.2007", volume = "27", pmcid = "PMC6673074" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200427-083757686, title = "Genetic Approaches Identify Differential Roles for α₄β₂* Nicotinic Receptors in Acute Models of Antinociception in Mice", journal = "Journal of Pharmacology and Experimental Therapeutics", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200427-083757686", id = "record", issn = "0022-3565", doi = "10.1124/jpet.106.112649", volume = "321" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150305-114442340, title = "Reversible Silencing of Neuronal Excitability in Behaving Mice by a Genetically Targeted, Ivermectin-Gated Cl^− Channel", journal = "Neuron", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150305-114442340", id = "record", issn = "0896-6273", doi = "10.1016/j.neuron.2007.02.030", volume = "54" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200416-150305764, title = "Unnatural Amino Acid Mutagenesis of the GABA\_A Receptor Binding Site Residues Reveals a Novel Cation-π Interaction between GABA and β₂Tyr97", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200416-150305764", id = "record", issn = "0270-6474", doi = "10.1523/jneurosci.4791-06.2007", volume = "27", pmcid = "PMC2649369" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170131-102250754, title = "Chemical-Scale Studies on the Role of a Conserved Aspartate in Preorganizing the Agonist Binding Site of the Nicotinic Acetylcholine Receptor", journal = "Biochemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170131-102250754", id = "record", issn = "0006-2960", doi = "10.1021/bi061638b", volume = "46", pmcid = "PMC3164877" } @article{https://resolver.caltech.edu/CaltechAUTHORS:AHEjgp06, title = "A Cation–π Interaction between Extracellular TEA and an Aromatic Residue in Potassium Channels", journal = "Journal of General Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:AHEjgp06", id = "record", issn = "0022-1295", doi = "10.1085/jgp.200609654", volume = "128", pmcid = "PMC2151593" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200427-095213669, title = "The Prototoxin lynx1 Acts on Nicotinic Acetylcholine Receptors to Balance Neuronal Activity and Survival In Vivo", journal = "Neuron", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200427-095213669", id = "record", issn = "0896-6273", doi = "10.1016/j.neuron.2006.07.025", volume = "51" } @article{https://resolver.caltech.edu/CaltechAUTHORS:RODpnas06, title = "In vivo incorporation of multiple unnatural amino acids through nonsense and frameshift suppression", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:RODpnas06", id = "record", issn = "0027-8424", doi = "10.1073/pnas.0510817103", volume = "103", pmcid = "PMC1482635" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170201-140122486, title = "Probing the Mg^(2+) Blockade Site of an N-Methyl-d-aspartate (NMDA) Receptor with Unnatural Amino Acid Mutagenesis", journal = "ACS Chemical Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170201-140122486", id = "record", issn = "1554-8929", doi = "10.1021/cb6000944", volume = "1" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170408-135451181, title = "Enhanced expression of hypersensitive α4* nAChR in adult mice increases the loss of midbrain dopaminergic neurons", journal = "FASEB Journal", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170408-135451181", id = "record", issn = "0892-6638", doi = "10.1096/fj.05-5497com", volume = "20" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200427-123125281, title = "Postsynaptic Mechanisms Are Essential for Forskolin-Induced Potentiation of Synaptic Transmission", journal = "Journal of Neurophysiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200427-123125281", id = "record", issn = "0022-3077", doi = "10.1152/jn.00617.2005", volume = "95" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200427-134509446, title = "CNS Localization of Neuronal Nicotinic Receptors", journal = "Journal of Molecular Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200427-134509446", id = "record", issn = "0895-8696", doi = "10.1385/jmn:30:1:181", volume = "30" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20110209-113037940, title = "CNS Localization of Neuronal Nicotinic Receptors", journal = "Journal of Molecular Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20110209-113037940", id = "record", issn = "0895-8696", doi = "10.1385/JMN:30:1:181", volume = "30" } @article{https://resolver.caltech.edu/CaltechAUTHORS:XIUjbc05, title = "A Unified View of the Role of Electrostatic Interactions in Modulating the Gating of Cys Loop Receptors", journal = "Journal of Biological Chemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:XIUjbc05", id = "record", issn = "0021-9258", doi = "10.1074/jbc.M508635200", volume = "280" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200427-144703784, title = "Novel Seizure Phenotype and Sleep Disruptions in Knock-In Mice with Hypersensitive α4* Nicotinic Receptors", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200427-144703784", id = "record", issn = "0270-6474", doi = "10.1523/jneurosci.3597-05.2005", volume = "25", pmcid = "PMC6725918" } @article{https://resolver.caltech.edu/CaltechAUTHORS:JANplosmed05.886, title = "Persistent amyloidosis following suppression of Aβ production in a transgenic model of Alzheimer disease", journal = "PLoS Medicine", url = "https://resolver.caltech.edu/CaltechAUTHORS:JANplosmed05.886", id = "record", issn = "1549-1676", doi = "10.1371/journal.pmed.0020355", volume = "2", pmcid = "PMC1283364" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150319-085128410, title = "Cis–trans isomerization at a proline opens the pore of a neurotransmitter-gated ion channel", journal = "Nature", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150319-085128410", id = "record", issn = "0028-0836", doi = "10.1038/nature04130", volume = "438" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200424-080629607, title = "A Cation-π Binding Interaction with a Tyrosine in the Binding Site of the GABA\_C Receptor", journal = "Chemistry and Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200424-080629607", id = "record", issn = "1074-5521", doi = "10.1016/j.chembiol.2005.06.012", volume = "12" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200428-121436325, title = "Mutations Linked to Autosomal Dominant Nocturnal Frontal Lobe Epilepsy Affect Allosteric Ca²⁺ Activation of the α4β2 Nicotinic Acetylcholine Receptor", journal = "Molecular Pharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200428-121436325", id = "record", issn = "0026-895X", doi = "10.1124/mol.105.011155", volume = "68" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200417-142718484, title = "An Angstrom Scale Interaction between Plasma Membrane ATP-Gated P2X₂ and α₄β₂ Nicotinic Channels Measured with Fluorescence Resonance Energy Transfer and Total Internal Reflection Fluorescence Microscopy", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200417-142718484", id = "record", issn = "0270-6474", doi = "10.1523/jneurosci.0561-05.2005", volume = "25", pmcid = "PMC6725363" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200506-072848149, title = "GABA Transporter Deficiency Causes Tremor, Ataxia, Nervousness, and Increased GABA-Induced Tonic Conductance in Cerebellum", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200506-072848149", id = "record", issn = "0270-6474", doi = "10.1523/jneurosci.3364-04.2005", volume = "25", pmcid = "PMC6725086" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200506-074200832, title = "D₂ Dopamine Receptors Colocalize Regulator of G-Protein Signaling 9-2 (RGS9-2) via the RGS9 DEP Domain, and RGS9 Knock-Out Mice Develop Dyskinesias Associated with Dopamine Pathways", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200506-074200832", id = "record", issn = "0270-6474", doi = "10.1523/jneurosci.2840-04.2005", volume = "25", pmcid = "PMC6726050" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170425-083958251, title = "Using Physical Chemistry To Differentiate Nicotinic from Cholinergic Agonists at the Nicotinic Acetylcholine Receptor", journal = "Journal of the American Chemical Society", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170425-083958251", id = "record", issn = "0002-7863", doi = "10.1021/ja0461771", volume = "127" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20141119-090016448, title = "Nicotine Activation of α4* Receptors: Sufficient for Reward, Tolerance, and Sensitization", journal = "Science", url = "https://resolver.caltech.edu/CaltechAUTHORS:20141119-090016448", id = "record", issn = "0036-8075", doi = "10.1126/science.1099420", volume = "306" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20130816-103138809, title = "Intrinsic Noise in Cultured Hippocampal Neurons: Experiment and Modeling", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20130816-103138809", id = "record", issn = "0270-6474", doi = "10.1523/JNEUROSCI.1721-04.2004", volume = "24", pmcid = "PMC6730144" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200427-084524229, title = "Tyrosine Residues That Control Binding and Gating in the 5-Hydroxytryptamine₃ Receptor Revealed by Unnatural Amino Acid Mutagenesis", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200427-084524229", id = "record", issn = "0270-6474", doi = "10.1523/jneurosci.2429-04.2004", volume = "24", pmcid = "PMC6730062" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170131-075938701, title = "On-Resin Assembly of a Linkerless Lanthanide(III)-Based Luminescence Label and Its Application to the Total Synthesis of Site-Specifically Labeled Mechanosensitive Channels", journal = "Bioconjugate Chemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170131-075938701", id = "record", issn = "1043-1802", doi = "10.1021/bc0498828", volume = "15" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200422-150959788, title = "Knockin mice with Leu9′Ser α4-nicotinic receptors: substantia nigra dopaminergic neurons are hypersensitive to agonist and lost postnatally", journal = "Physiological Genomics", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200422-150959788", id = "record", issn = "1094-8341", doi = "10.1152/physiolgenomics.00012.2004", volume = "18" } @article{https://resolver.caltech.edu/CaltechAUTHORS:SHAjgp04, title = "Gating Transitions in Bacterial Ion Channels Measured at 3 µs Resolution", journal = "Journal of General Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:SHAjgp04", id = "record", issn = "0022-1295", doi = "10.1085/jgp.200409087", volume = "124", pmcid = "PMC2229625" } @article{https://resolver.caltech.edu/CaltechAUTHORS:DAHpnas04, title = "A fluorophore attached to nicotinic acetylcholine receptor beta M2 detects productive binding of agonist to the alpha delta site", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:DAHpnas04", id = "record", issn = "0027-8424", doi = "10.1073/pnas.0301885101", volume = "101", pmcid = "PMC454187" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200513-072838651, title = "Uropathic Observations in Mice Expressing a Constitutively Active Point Mutation in the 5-HT\_(3A) Receptor Subunit", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200513-072838651", id = "record", issn = "0270-6474", doi = "10.1523/jneurosci.5658-03.2004", volume = "24", pmcid = "PMC6729324" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200427-094708016, title = "Cys-loop receptors: new twists and turns", journal = "Trends in Neurosciences", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200427-094708016", id = "record", issn = "0166-2236", doi = "10.1016/j.tins.2004.04.002", volume = "27" } @article{https://resolver.caltech.edu/CaltechAUTHORS:CLApnas04, title = "Total chemical synthesis and electrophysiological characterization of mechanosensitive channels from Escherichia coli and Mycobacterium tuberculosis", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:CLApnas04", id = "record", issn = "0027-8424", doi = "10.1073/pnas.0305693101", volume = "101", pmcid = "PMC387322" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20160212-092320526, title = "Assembly of α4β2 Nicotinic Acetylcholine Receptors Assessed with Functional Fluorescently Labeled Subunits: Effects of Localization, Trafficking, and Nicotine-Induced Upregulation in Clonal Mammalian Cells and in Cultured Midbrain Neurons", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160212-092320526", id = "record", issn = "0270-6474", doi = "10.1523/jneurosci.23-37-11554.2003", volume = "23", pmcid = "PMC6740951" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20180313-125205786, title = "International Union of Pharmacology. XLI. Compendium of Voltage-Gated Ion Channels: Potassium Channels", journal = "Pharmacological Reviews", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180313-125205786", id = "record", issn = "0031-6997", doi = "10.1124/pr.55.4.9", volume = "55" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200514-153422419, title = "α4β2* Nicotinic Acetylcholine Receptors Modulate the Effects of Ethanol and Nicotine on the Acoustic Startle Response", journal = "Alcoholism: Clinical and Experimental Research", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200514-153422419", id = "record", issn = "0145-6008", doi = "10.1097/01.alc.0000102700.72447.0f", volume = "27" } @article{https://resolver.caltech.edu/CaltechAUTHORS:LEIpnas03, title = "Conformation-dependent hydrophobic photolabeling of the nicotinic receptor: Electrophysiology-coordinated photochemistry and mass spectrometry", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:LEIpnas03", id = "record", issn = "0027-8424", doi = "10.1073/pnas.2133028100", volume = "100", pmcid = "PMC240743" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200428-095147178, title = "GABA Transporter-1 (GAT1)-Deficient Mice: Differential Tonic Activation of GABA\_A Versus GABA\_B Receptors in the Hippocampus", journal = "Journal of Neurophysiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200428-095147178", id = "record", issn = "0022-3077", doi = "10.1152/jn.00240.2003", volume = "90" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200427-151732404, title = "Functional characterization of dopaminergic neurons derived from rodent mesencephalic progenitor cells", journal = "Journal of Chemical Neuroanatomy", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200427-151732404", id = "record", issn = "0891-0618", doi = "10.1016/s0891-0618(03)00067-x", volume = "26" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200428-093705406, title = "Hypersensitive knockin mouse strains identify receptors and pathways for nicotine action", journal = "Current opinion in drug discovery \& development", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200428-093705406", id = "record", issn = "1367-6733", volume = "6" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200417-142717107, title = "Investigation of apparent mass deviations in electrospray ionization tandem mass spectrometry of a benzophenone-labeled peptide", journal = "Rapid Communications in Mass Spectrometry", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200417-142717107", id = "record", issn = "0951-4198", doi = "10.1002/rcm.1103", volume = "17" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200515-112555466, title = "Requirement of a critical period of GABAergic receptor blockade for induction of a cAMP-mediated long-term depression at CA3-CA1 synapses", journal = "Synapse", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200515-112555466", id = "record", issn = "0887-4476", doi = "10.1002/syn.10207", volume = "49" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200428-095147285, title = "Five ADNFLE Mutations Reduce the Ca²⁺ Dependence of the Mammalian α4β2 Acetylcholine Response", journal = "Journal of Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200428-095147285", id = "record", issn = "0022-3751", doi = "10.1113/jphysiol.2003.036681", volume = "550", pmcid = "PMC2343021" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200515-125021148, title = "RGS9 Modulates Dopamine Signaling in the Basal Ganglia", journal = "Neuron", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200515-125021148", id = "record", issn = "0896-6273", doi = "10.1016/s0896-6273(03)00321-0", volume = "38" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170510-080843497, title = "Different Binding Orientations for the Same Agonist at Homologous Receptors: A Lock and Key or a Simple Wedge?", journal = "Journal of the American Chemical Society", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170510-080843497", id = "record", issn = "0002-7863", doi = "10.1021/ja0348086", volume = "125" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200427-123619296, title = "Unnatural amino acid mutagenesis in mapping ion channel function", journal = "Current Opinion in Neurobiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200427-123619296", id = "record", issn = "0959-4388", doi = "10.1016/s0959-4388(03)00068-0", volume = "13" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200427-134043259, title = "Site-Specific Incorporation of Unnatural Amino Acids into Receptors Expressed in Mammalian Cells", journal = "Chemistry and Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200427-134043259", id = "record", issn = "1074-5521", doi = "10.1016/s1074-5521(03)00124-8", volume = "10" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20190927-090347351, title = "Increased Sensitivity to Agonist-Induced Seizures, Straub Tail, and Hippocampal Theta Rhythm in Knock-In Mice Carrying Hypersensitive α4 Nicotinic Receptors", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20190927-090347351", id = "record", issn = "0270-6474", doi = "10.1523/jneurosci.23-07-02582.2003", volume = "23", pmcid = "PMC6742094" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20141212-145345633, title = "Open-State Disulfide Crosslinking between Mycobacterium tuberculosis Mechanosensitive Channel Subunits", journal = "Biophysical Journal", url = "https://resolver.caltech.edu/CaltechAUTHORS:20141212-145345633", id = "record", issn = "0006-3495", doi = "10.1016/S0006-3495(03)75041-3", volume = "84", pmcid = "PMC1302802" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200626-123755093, title = "Codon optimization of Caenorhabditis elegans GluCl ion channel genes for mammalian cells dramatically improves expression levels", journal = "Journal of Neuroscience Methods", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200626-123755093", id = "record", issn = "0165-0270", doi = "10.1016/s0165-0270(02)00362-x", volume = "124" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200612-075804212, title = "Time course of inner ear degeneration and deafness in mice lacking the Kir4.1 potassium channel subunit", journal = "Hearing Research", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200612-075804212", id = "record", issn = "0378-5955", doi = "10.1016/s0378-5955(02)00799-2", volume = "177" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20111011-100601324, title = "Insights into channel function via channel dysfunction", journal = "Journal of Clinical Investigation", url = "https://resolver.caltech.edu/CaltechAUTHORS:20111011-100601324", id = "record", issn = "0021-9738", doi = "10.1172/JCI200317882", volume = "111", pmcid = "PMC151932" } @inbook{https://resolver.caltech.edu/CaltechAUTHORS:20200417-142717296, title = "Biophotonics, Part A", chapter = "Caging proteins through unnatural amino acids mutagenesis", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200417-142717296", id = "record", isbn = "9780121822637", doi = "10.1016/s0076-6879(03)60114-x" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20190930-133756603, title = "Number, Density, and Surface/Cytoplasmic Distribution of GABA Transporters at Presynaptic Structures of Knock-In Mice Carrying GABA Transporter Subtype 1–Green Fluorescent Protein Fusions", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20190930-133756603", id = "record", issn = "0270-6474", doi = "10.1523/jneurosci.22-23-10251.2002", volume = "22", pmcid = "PMC6758747" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170414-144546207, title = "A Perturbed pK\_a at the Binding Site of the Nicotinic Acetylcholine Receptor: Implications for Nicotine Binding", journal = "Journal of the American Chemical Society", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170414-144546207", id = "record", issn = "0002-7863", doi = "10.1021/ja028206i", volume = "124" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200612-113333592, title = "Selective elimination of glutamate activation and introduction of fluorescent proteins into a Caenorhabditis elegans chloride channel", journal = "FEBS Letters", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200612-113333592", id = "record", issn = "0014-5793", doi = "10.1016/s0014-5793(02)03245-3", volume = "528" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150303-122051974, title = "Selective Electrical Silencing of Mammalian Neurons In Vitro by the Use of Invertebrate Ligand-Gated Chloride Channels", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150303-122051974", id = "record", issn = "0270-6474", doi = "10.1523/JNEUROSCI.22-17-07373.2002", volume = "22", pmcid = "PMC6757961" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170125-110549324, title = "Cation−π Interactions in Ligand Recognition by Serotonergic (5-HT\_(3A)) and Nicotinic Acetylcholine Receptors: The Anomalous Binding Properties of Nicotine", journal = "Biochemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170125-110549324", id = "record", issn = "0006-2960", doi = "10.1021/bi020266d", volume = "41" } @article{https://resolver.caltech.edu/CaltechAUTHORS:EICjgp02, title = "Control of P2X2 Channel Permeability by the Cytosolic Domain", journal = "Journal of General Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:EICjgp02", id = "record", issn = "0022-1295", doi = "10.1085/jgp.20028535", volume = "120", pmcid = "PMC2234464" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200612-113333889, title = "Early Fluorescence Signals Detect Transitions at Mammalian Serotonin Transporters", journal = "Biophysical Journal", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200612-113333889", id = "record", issn = "0006-3495", doi = "10.1016/s0006-3495(02)75162-x", volume = "83", pmcid = "PMC1302140" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200612-113333802, title = "NRSF Causes cAMP-Sensitive Suppression of Sodium Current in Cultured Hippocampal Neurons", journal = "Journal of Neurophysiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200612-113333802", id = "record", issn = "0022-3077", doi = "10.1152/jn.2002.88.1.409", volume = "88" } @article{https://resolver.caltech.edu/CaltechAUTHORS:PETrnao02, title = "MALDI-TOF mass spectrometry methods for evaluation of in vitro aminoacyl tRNA production", journal = "RNA", url = "https://resolver.caltech.edu/CaltechAUTHORS:PETrnao02", id = "record", issn = "1355-8382", volume = "8", pmcid = "PMC1370275" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200612-113333997, title = "Voltage-dependent transient currents of human and rat 5-HT transporters (SERT) are blocked by HEPES and ion channel ligands", journal = "FEBS Letters", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200612-113333997", id = "record", issn = "0014-5793", doi = "10.1016/s0014-5793(02)02322-0", volume = "513" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200612-113334102, title = "Gi Irks GIRKs", journal = "Neuron", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200612-113334102", id = "record", issn = "0896-6273", doi = "10.1016/s0896-6273(01)00572-4", volume = "33" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20160210-145519981, title = "Kir4.1 Potassium Channel Subunit Is Crucial for Oligodendrocyte Development and In Vivo Myelination", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160210-145519981", id = "record", issn = "0270-6474", doi = "10.1523/JNEUROSCI.21-15-05429.2001", volume = "21", pmcid = "PMC6762664" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200506-103644435, title = "Incorporation of caged cysteine and caged tyrosine into a transmembrane segment of the nicotinic ACh receptor", journal = "American Journal of Physiology. Cell Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200506-103644435", id = "record", issn = "0363-6143", doi = "10.1152/ajpcell.2001.281.1.c195", volume = "281" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200612-115646273, title = "Ion Channel Diseases of the Central Nervous System", journal = "CNS Drug Reviews", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200612-115646273", id = "record", issn = "1080-563X", doi = "10.1111/j.1527-3458.2001.tb00196.x", volume = "7", pmcid = "PMC6741647" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150327-103308333, title = "Neurobiology: Snails, synapses and smokers", journal = "Nature", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150327-103308333", id = "record", issn = "0028-0836", doi = "10.1038/35077192", volume = "411" } @article{https://resolver.caltech.edu/CaltechAUTHORS:YUTpnas01, title = "gamma-Aminobutyric acid type A receptors modulate cAMP-mediated long-term potentiation and long-term depression at monosynaptic CA3-CA1 synapses", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:YUTpnas01", id = "record", issn = "0027-8424", doi = "10.1073/pnas.091093998", volume = "98", pmcid = "PMC33198" } @article{https://resolver.caltech.edu/CaltechAUTHORS:KHApnas01a, title = "Activation-dependent changes in receptor distribution and dendritic morphology in hippocampal neurons expressing P2X(2)-green fluorescent protein receptors", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:KHApnas01a", id = "record", issn = "0027-8424", doi = "10.1073/pnas.081089198", volume = "98", pmcid = "PMC33202" } @article{https://resolver.caltech.edu/CaltechAUTHORS:LABpnas01, title = "Point mutant mice with hypersensitive alpha 4 nicotinic receptors show dopaminergic deficits and increased anxiety", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:LABpnas01", id = "record", issn = "0027-8424", doi = "10.1073/pnas.041582598", volume = "98", pmcid = "PMC30217" } @article{https://resolver.caltech.edu/CaltechAUTHORS:TONjgp01, title = "Tyrosine decaging leads to substantial membrane trafficking during modulation of an inward rectifier potassium channel", journal = "Journal of General Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:TONjgp01", id = "record", issn = "0022-1295", doi = "10.1085/jgp.117.2.103", volume = "117", pmcid = "PMC2217249" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200612-115646402, title = "Single-molecule measurements calibrate green fluorescent protein surface densities on transparent beads for use with 'knock-in' animals and other expression systems", journal = "Journal of Neuroscience Methods", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200612-115646402", id = "record", issn = "0165-0270", doi = "10.1016/s0165-0270(00)00354-x", volume = "105" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200422-150959147, title = "The tethered agonist approach to mapping ion channel proteins – toward a structural model for the agonist binding site of the nicotinic acetylcholine receptor", journal = "Chemistry and Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200422-150959147", id = "record", issn = "1074-5521", doi = "10.1016/s1074-5521(00)00055-7", volume = "8" } @article{https://resolver.caltech.edu/CaltechAUTHORS:CHIjeb00, title = "The transporter-like protein inebriated mediates hyperosmotic stimuli through intracellular signaling", journal = "Journal of Experimental Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:CHIjeb00", id = "record", issn = "0022-0949", volume = "203" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200612-115646596, title = "Modulation of early growth response (EGR) transcription factor-dependent gene expression by using recombinant adenovirus", journal = "Gene", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200612-115646596", id = "record", issn = "0378-1119", doi = "10.1016/s0378-1119(00)00445-5", volume = "258" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200612-132259782, title = "Genetic Inactivation of an Inwardly Rectifying Potassium Channel (Kir4.1 Subunit) in Mice: Phenotypic Impact in Retina", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200612-132259782", id = "record", issn = "0270-6474", doi = "10.1523/jneurosci.20-15-05733.2000", volume = "20", pmcid = "PMC2410027" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150306-095241138, title = "ROMK1 (Kir1.1) Causes Apoptosis and Chronic Silencing of Hippocampal Neurons", journal = "Journal of Neurophysiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150306-095241138", id = "record", issn = "0022-3077", doi = "10.1152/jn.2000.84.2.1062", volume = "84" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150327-133158044, title = "State-dependent cross-inhibition between transmitter-gated cation channels", journal = "Nature", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150327-133158044", id = "record", issn = "0028-0836", doi = "10.1038/35019066", volume = "406" } @article{https://resolver.caltech.edu/CaltechAUTHORS:MAUjbc00, title = "Comparing and contrasting Escherichia coli and Mycobacterium tuberculosis mechanosensitive channels (MscL) - New gain of function mutations in the loop region", journal = "Journal of Biological Chemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:MAUjbc00", id = "record", issn = "0021-9258", doi = "10.1074/jbc.M003056200", volume = "275" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20181213-110051972, title = "Two-compartment model for whole-cell data analysis and transient compensation", journal = "Journal of Neuroscience Methods", url = "https://resolver.caltech.edu/CaltechAUTHORS:20181213-110051972", id = "record", issn = "0165-0270", doi = "10.1016/s0165-0270(00)00210-7", volume = "99" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200513-070503095, title = "Probing the Role of a Conserved M1 Proline Residue in 5-Hydroxytryptamine₃ Receptor Gating", journal = "Molecular Pharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200513-070503095", id = "record", issn = "0026-895X", volume = "57" } @article{https://resolver.caltech.edu/CaltechAUTHORS:LIMjgp00, title = "An Intermediate State of the {gamma}-Aminobutyric Acid Transporter GAT1 Revealed by Simultaneous Voltage Clamp and Fluorescence", journal = "Journal of General Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:LIMjgp00", id = "record", issn = "0022-1295", doi = "10.1085/jgp.115.4.491", volume = "115", pmcid = "PMC2233755" } @article{https://resolver.caltech.edu/CaltechAUTHORS:LESarn00, title = "Gain of function mutants: Ion channels and G protein-coupled receptors", journal = "Annual Review of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:LESarn00", id = "record", issn = "0147-006X", doi = "10.1146/annurev.neuro.23.1.89", volume = "23" } @article{https://resolver.caltech.edu/CaltechAUTHORS:KOVjbc00, title = "Co-expression of Gbeta 5 Enhances the Function of Two Ggamma Subunit-like Domain-containing Regulators of G Protein Signaling Proteins", journal = "Journal of Biological Chemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:KOVjbc00", id = "record", issn = "0021-9258", volume = "275" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200612-132259910, title = "Expression of GIRK (Kir3.1/Kir3.4) channels in mouse fibroblast cells with and without β1 integrins", journal = "FEBS Letters", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200612-132259910", id = "record", issn = "0014-5793", doi = "10.1016/s0014-5793(99)01738-x", volume = "466" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200612-132300221, title = "Single-Molecule Fluorescence Observed with Mercury Lamp Illumination", journal = "BioTechniques", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200612-132300221", id = "record", issn = "0736-6205", doi = "10.2144/99275rr01", volume = "27" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20180313-080855191, title = "Mapping Disulfide Connectivity Using Backbone Ester Hydrolysis", journal = "Biochemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180313-080855191", id = "record", issn = "0006-2960", doi = "10.1021/bi991424c", volume = "38" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20191028-115507054, title = "Allosteric Control of Gating and Kinetics at P2X₄ Receptor Channels", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20191028-115507054", id = "record", issn = "0270-6474", doi = "10.1523/jneurosci.19-17-07289.1999", volume = "19", pmcid = "PMC6782529" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200626-123754307, title = "Dynamic Selectivity Filters in Ion Channels", journal = "Neuron", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200626-123754307", id = "record", issn = "0896-6273", doi = "10.1016/s0896-6273(01)80025-8", volume = "23" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200626-123656741, title = "Single-channel kinetics of the rat olfactory cyclic nucleotide-gated channel expressed in Xenopus oocytes", journal = "Molecular Pharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200626-123656741", id = "record", issn = "0026-895X", volume = "55" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200626-123655847, title = "Functional roles of aromatic residues in the ligand-binding domain of cyclic nucleotide-gated channels", journal = "Molecular Pharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200626-123655847", id = "record", issn = "0026-895X", volume = "55" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150414-095506624, title = "Neuronal P2X transmitter-gated cation channels change their ion selectivity in seconds", journal = "Nature Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150414-095506624", id = "record", issn = "1097-6256", doi = "10.1038/7233", volume = "2" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200514-152725398, title = "Backbone Mutations in Transmembrane Domains of a Ligand-Gated Ion Channel: Implications for the Mechanism of Gating", journal = "Cell", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200514-152725398", id = "record", issn = "0092-8674", doi = "10.1016/s0092-8674(00)80962-9", volume = "96" } @article{https://resolver.caltech.edu/CaltechAUTHORS:MCPjbc98, title = "Evidence for a Functional Interaction between Integrins and G Protein-activated Inward Rectifier K+ Channels", journal = "Journal of Biological Chemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:MCPjbc98", id = "record", issn = "0021-9258", volume = "273" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220223-204480000, title = "Enhancement of Neurotransmitter Release Induced by Brain-Derived Neurotrophic Factor in Cultured Hippocampal Neurons", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220223-204480000", id = "record", issn = "0270-6474", doi = "10.1523/jneurosci.18-24-10231.1998", volume = "18", pmcid = "PMC6793341" } @article{https://resolver.caltech.edu/CaltechAUTHORS:ZHPpnas98, title = "From ab initio quantum mechanics to molecular neurobiology: A cation-pi binding site in the nicotinic receptor", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:ZHPpnas98", id = "record", issn = "0027-8424", doi = "10.1073/pnas.95.21.12088", volume = "95", pmcid = "PMC22789" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20220223-204499000, title = "Amino Acid Residues that Control pH Modulation of Transport-Associated Current in Mammalian Serotonin Transporters", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220223-204499000", id = "record", issn = "0270-6474", doi = "10.1523/jneurosci.18-19-07739.1998", volume = "18", pmcid = "PMC6793029" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20180508-083019710, title = "The Crystal Structure of a Potassium Channel — A New Era in the Chemistry of Biological Signaling", journal = "Angewandte Chemie International Edition", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180508-083019710", id = "record", issn = "1433-7851", doi = "10.1002/(SICI)1521-3773(19980918)37:17<2329::AID-ANIE2329>3.0.CO;2-M", volume = "37" } @article{https://resolver.caltech.edu/CaltechAUTHORS:LIYpnas98, title = "Expression of a dominant negative TrkB receptor, T1, reveals a requirement for presynaptic signaling in BDNF-induced synaptic potentiation in cultured hippocampal neurons", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:LIYpnas98", id = "record", issn = "0027-8424", volume = "95", pmcid = "PMC27990" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200513-104033054, title = "Asymmetrical Contributions of Subunit Pore Regions to Ion Selectivity in an Inward Rectifier K⁺ Channel", journal = "Biophysical Journal", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200513-104033054", id = "record", issn = "0006-3495", doi = "10.1016/s0006-3495(98)74051-2", volume = "75", pmcid = "PMC1299807" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200515-132054818, title = "Flash Decaging of Tyrosine Sidechains in an Ion Channel", journal = "Neuron", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200515-132054818", id = "record", issn = "0896-6273", doi = "10.1016/s0896-6273(00)81001-6", volume = "20" } @article{https://resolver.caltech.edu/CaltechAUTHORS:LESjgp98, title = "New Views of Multi-Ion Channels", journal = "Journal of General Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:LESjgp98", id = "record", issn = "0022-1295", doi = "10.1085/jgp.111.2.181", volume = "111", pmcid = "PMC2222761" } @inbook{https://resolver.caltech.edu/CaltechAUTHORS:20200515-134619162, title = "Ion Channels Part B", chapter = "In vivo incorporation of unnatural amino acids into ion channels in Xenopus oocyte expression system", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200515-134619162", id = "record", isbn = "978-0-12-182194-4", doi = "10.1016/s0076-6879(98)93031-2" } @article{https://resolver.caltech.edu/CaltechAUTHORS:WESjbc97, title = "Expression and Circular Dichroism Studies of the Extracellular Domain of the alpha Subunit of the Nicotinic Acetylcholine Receptor", journal = "Journal of Biological Chemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:WESjbc97", id = "record", issn = "0021-9258", doi = "10.1074/jbc.272.41.25468", volume = "272" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200515-142830762, title = "Site-specific incorporation of biotinylated amino acids to identify surface-exposed residues in integral membrane proteins", journal = "Chemistry and Biology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200515-142830762", id = "record", issn = "1074-5521", doi = "10.1016/s1074-5521(97)90312-4", volume = "4" } @article{https://resolver.caltech.edu/CaltechAUTHORS:ENGpnas97, title = "Site-specific, photochemical proteolysis applied to ion channels in vivo", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:ENGpnas97", id = "record", issn = "0027-8424", doi = "10.1073/pnas.94.20.11025", volume = "94", pmcid = "PMC23572" } @article{https://resolver.caltech.edu/CaltechAUTHORS:DOUpnas97, title = "RGS proteins reconstitute the rapid gating kinetics of Gβγ-activated inwardly rectifying K^+ channels", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:DOUpnas97", id = "record", issn = "0027-8424", volume = "94", pmcid = "PMC23385" } @article{https://resolver.caltech.edu/CaltechAUTHORS:EHRpnas97, title = "Activation of heteromeric G protein-gated inward rectifier K+ channels overexpressed by adenovirus gene transfer inhibits the excitability of hippocampal neurons", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:EHRpnas97", id = "record", issn = "0027-8424", volume = "94", pmcid = "PMC21286" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20191030-140944005, title = "Second Messengers, Trafficking-Related Proteins, and Amino Acid Residues that Contribute to the Functional Regulation of the Rat Brain GABA Transporter GAT1", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20191030-140944005", id = "record", issn = "0270-6474", doi = "10.1523/jneurosci.17-09-02967.1997", volume = "17", pmcid = "PMC6573650" } @article{https://resolver.caltech.edu/CaltechAUTHORS:LIJqrb97, title = "Cyclic nucleotide-gated channels: structural basis of ligand efficacy and allosteric modulation", journal = "Quarterly Reviews of Biophysics", url = "https://resolver.caltech.edu/CaltechAUTHORS:LIJqrb97", id = "record", issn = "0033-5835", volume = "30" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20191030-144551486, title = "H⁺ Permeation and pH Regulation at a Mammalian Serotonin Transporter", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20191030-144551486", id = "record", issn = "0270-6474", doi = "10.1523/jneurosci.17-07-02257.1997", volume = "17", pmcid = "PMC6573487" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20160401-135631881, title = {Functional Expression of the Heteromeric "Olfactory" Cyclic Nucleotide-Gated Channel in the Hippocampus: A Potential Effector of Synaptic Plasticity in Brain Neurons}, journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160401-135631881", id = "record", issn = "0270-6474", doi = "10.1523/JNEUROSCI.17-06-01993.1997", volume = "17", pmcid = "PMC6793760" } @article{https://resolver.caltech.edu/CaltechAUTHORS:SILpnas96, title = "A regenerative link in the ionic fluxes through the weaver potassium channel underlies the pathophysiology of the mutation", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:SILpnas96", id = "record", issn = "0027-8424", doi = "10.1073/pnas.93.26.15429", volume = "93", pmcid = "PMC26421" } @article{https://resolver.caltech.edu/CaltechAUTHORS:QUIjbc96, title = "Desensitization of Inositol 1,4,5-Trisphosphate/Ca2+-induced Cl- Currents by Prolonged Activation of G Proteins in Xenopus Oocytes", journal = "Journal of Biological Chemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:QUIjbc96", id = "record", issn = "0021-9258", volume = "271" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200518-070216780, title = "Determinants of Nicotinic Receptor Gating in Natural and Unnatural Side Chain Structures at the M2 9′ Position", journal = "Neuron", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200518-070216780", id = "record", issn = "0896-6273", doi = "10.1016/s0896-6273(00)80252-4", volume = "17" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120207-144820693, title = "Subunit Stoichiometry of a Heteromultimeric G protein-coupled Inward-rectifier K^+ Channel", journal = "Journal of Biological Chemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120207-144820693", id = "record", issn = "0021-9258", doi = "10.1074/jbc.271.48.30524", volume = "271" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20200626-123657699, title = "Dose-response relations for unnatural amino acids at the agonist binding site of the nicotinic acetylcholine receptor: tests with novel side chains and with several agonists", journal = "Molecular Pharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200626-123657699", id = "record", issn = "0026-895X", volume = "50" } @article{https://resolver.caltech.edu/CaltechAUTHORS:SAKjbc96, title = "An engineered Tetrahymena tRNA(Gln) for in vivo incorporation of unnatural amino acids into proteins by nonsense suppression", journal = "Journal of Biological Chemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:SAKjbc96", id = "record", issn = "0021-9258", volume = "271" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20191030-155045434, title = "Ion Binding and Permeation at the GABA Transporter GAT1", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20191030-155045434", id = "record", issn = "0270-6474", doi = "10.1523/jneurosci.16-17-05405.1996", volume = "16", pmcid = "PMC6578888" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150610-111824247, title = "Inhibition of an inwardly rectifying K^+ channel by G-protein ɑ-subunits", journal = "Nature", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150610-111824247", id = "record", issn = "0028-0836", doi = "10.1038/380624a0", volume = "380" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120208-075012754, title = "Voltage-Jump Relaxation Kinetics for Wild-type and Chimeric β Subunits of Neuronal Nicotinic Receptors", journal = "Journal of General Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120208-075012754", id = "record", issn = "0022-1295", doi = "10.1085/jgp.107.3.369", volume = "107", pmcid = "PMC2216994" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20110620-160434844, title = "A multi-substrate single-file model for ion-coupled transporters", journal = "Biophysical Journal", url = "https://resolver.caltech.edu/CaltechAUTHORS:20110620-160434844", id = "record", issn = "0006-3495", doi = "10.1016/S0006-3495(96)79616-9", volume = "70", pmcid = "PMC1224976" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150610-113831280, title = "Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors", journal = "Nature", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150610-113831280", id = "record", issn = "0028-0836", doi = "10.1038/376514a0", volume = "376" } @article{https://resolver.caltech.edu/CaltechAUTHORS:DASpnas95, title = "Inhibition of function in Xenopus oocytes of the inwardly rectifying G-protein-activated atrial K channel (GIRK1) by overexpression of a membrane-attached form of the C-terminal tail", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:DASpnas95", id = "record", issn = "0027-8424", doi = "10.1073/pnas.92.15.6758", volume = "92", pmcid = "PMC41408" } @article{https://resolver.caltech.edu/CaltechAUTHORS:KOFpnas95, title = "Evidence that neuronal G-protein-gated inwardly rectifying K+ channels are activated by Gβγ subunits and function as heteromultimers", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:KOFpnas95", id = "record", issn = "0027-8424", doi = "10.1073/pnas.92.14.6542", volume = "92", pmcid = "PMC41554" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120216-103326772, title = "Intrinsic Gating Properties of a Cloned G Protein-activated Inward Rectifier K^+ Channel", journal = "Journal of General Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120216-103326772", id = "record", issn = "0022-1295", doi = "10.1085/jgp.106.1.1", volume = "106", pmcid = "PMC2229253" } @article{https://resolver.caltech.edu/CaltechAUTHORS:COHjgp95, title = "Regions of beta 2 and beta 4 responsible for differences between the steady state dose-response relationships of the alpha 3 beta 2 and alpha 3 beta 4 neuronal nicotinic receptors", journal = "Journal of General Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:COHjgp95", id = "record", issn = "0022-1295", doi = "10.1085/jgp.107.3.369", volume = "105", pmcid = "PMC2216958" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150120-140412390, title = "Nicotinic Receptor Binding Site Probed with Unnatural Amino Acid Incorporation in Intact Cells", journal = "Science", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150120-140412390", id = "record", issn = "0036-8075", doi = "10.1126/science.7716551", volume = "268" } @article{https://resolver.caltech.edu/CaltechAUTHORS:LIMjgp95, title = "A G protein-gated K channel is activated via beta 2-adrenergic receptors and G beta gamma subunits in Xenopus oocytes", journal = "Journal of General Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:LIMjgp95", id = "record", issn = "0022-1295", doi = "10.1085/jgp.105.3.421", volume = "105", pmcid = "PMC2216943" } @article{https://resolver.caltech.edu/CaltechAUTHORS:QUIjbc94, title = "Differential coupling of G protein alpha subunits to seven-helix receptors expressed in Xenopus oocytes", journal = "Journal of Biological Chemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:QUIjbc94", id = "record", issn = "0021-9258", volume = "269" } @article{https://resolver.caltech.edu/CaltechAUTHORS:BRApnas94, title = "Heteromeric olfactory cyclic nucleotide-gated channels: a subunit that confers increased sensitivity to cAMP", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:BRApnas94", id = "record", issn = "0027-8424", volume = "91", pmcid = "PMC44712" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170408-205029469, title = "Distribution and localization of a G protein-coupled inwardly rectifying K⁺ channel in the rat", journal = "FEBS Letters", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170408-205029469", id = "record", issn = "0014-5793", doi = "10.1016/0014-5793(94)00590-7", volume = "348" } @article{https://resolver.caltech.edu/CaltechAUTHORS:CORjbc94, title = "Protein kinase C modulates the activity of a cloned gamma-aminobutyric acid transporter expressed in Xenopus oocytes via regulated subcellular redistribution of the transporter", journal = "Journal of Biological Chemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:CORjbc94", id = "record", issn = "0021-9258", volume = "269" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120222-112704352, title = "Permeation Properties of Neurotransmitter Transporters", journal = "Annual Review of Pharmacology and Toxicology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120222-112704352", id = "record", issn = "0362-1642", doi = "10.1146/annurev.pharmtox.34.1.219", volume = "34" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20141210-095231086, title = "A cocaine-sensitive Drosophila serotonin transporter: Cloning, expression, and electrophysiological characterization", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:20141210-095231086", id = "record", issn = "0027-8424", volume = "91", pmcid = "PMC521479" } @article{https://resolver.caltech.edu/CaltechAUTHORS:DASpnas93b, title = "Atrial G protein-activated K+ channel: expression cloning and molecular properties", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:DASpnas93b", id = "record", issn = "0027-8424", doi = "10.1073/pnas.90.21.10235", volume = "90", pmcid = "PMC47749" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120307-154341054, title = "Random Mutagenesis of G protein ɑ Subunit G\_oɑ. Mutations altering nucleotide binding", journal = "Journal of Biological Chemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120307-154341054", id = "record", issn = "0021-9258", volume = "268" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150609-125940793, title = "The response to vagusstoff", journal = "Nature", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150609-125940793", id = "record", issn = "0028-0836", doi = "10.1038/364758a0", volume = "364" } @article{https://resolver.caltech.edu/CaltechAUTHORS:DASpnas93, title = "Expression of an atrial G-protein-activated potassium channel in Xenopus oocytes", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:DASpnas93", id = "record", issn = "0027-8424", doi = "10.1073/pnas.90.14.6596", volume = "90", pmcid = "PMC46979" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120309-113518954, title = "Voltage-dependent Block of the Cystic Fibrosis Transmembrane Conductance Regulator Cl- Channel by Two Closely Related Arylaminobenzoates", journal = "Journal of General Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120309-113518954", id = "record", issn = "0022-1295", doi = "10.1085/jgp.102.1.1", volume = "102", pmcid = "PMC2229162" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20151217-104726852, title = "Receptors that couple to 2 classes of G proteins increase cAMP and activate CFTR expressed in Xenopus oocytes", journal = "Receptors \& Channels", url = "https://resolver.caltech.edu/CaltechAUTHORS:20151217-104726852", id = "record", issn = "1060-6823", volume = "1" } @article{https://resolver.caltech.edu/CaltechAUTHORS:COHjgp92a, title = "Mutations in M2 alter the selectivity of the mouse nicotinic acetylcholine receptor for organic and alkali metal cations", journal = "Journal of General Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:COHjgp92a", id = "record", issn = "0022-1295", doi = "10.1085/jgp.100.3.373", volume = "100", pmcid = "PMC2229089" } @article{https://resolver.caltech.edu/CaltechAUTHORS:GUApnas92, title = "Cloning, expression, and localization of a rat brain high-affinity glycine transporter", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:GUApnas92", id = "record", issn = "0027-8424", doi = "10.1073/pnas.89.15.7189", volume = "89", pmcid = "PMC49671" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120329-091749403, title = "The Permeation Pathway of Neurotransmitter-Gated Ion Channels", journal = "Annual Review of Biophysics and Biomolecular Structure", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120329-091749403", id = "record", issn = "1056-8700", doi = "10.1146/annurev.bb.21.060192.001411", volume = "21" } @article{https://resolver.caltech.edu/CaltechAUTHORS:COHjgp92b, title = "Tris+/Na+ permeability ratios of nicotinic acetylcholine receptors are reduced by mutations near the intracellular end of the M2 region", journal = "Journal of General Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:COHjgp92b", id = "record", issn = "0022-1295", doi = "10.1085/jgp.99.4.545", volume = "99", pmcid = "PMC2219204" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20191101-161058438, title = "Cell-specific posttranslational events affect functional expression at the plasma membrane but not tetrodotoxin sensitivity of the rat brain IIA sodium channel α-subunit expressed in mammalian cells", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20191101-161058438", id = "record", issn = "0270-6474", doi = "10.1523/jneurosci.12-01-00268.1992", volume = "12", pmcid = "PMC6575683" } @article{https://resolver.caltech.edu/CaltechAUTHORS:LESarp91, title = "Strategies for studying permeation at voltage-gated ion channels", journal = "Annual Review of Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:LESarp91", id = "record", issn = "0066-4278", volume = "53" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120420-071637268, title = "Low Molecular Weight mRNA Encodes a Protein That Controls Serotonin 5-HT\_(1c) and Acetylcholine M\_1 Receptor Sensitivity in Xenopus Oocytes", journal = "Journal of General Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120420-071637268", id = "record", issn = "0022-1295", doi = "10.1085/jgp.98.2.399", volume = "98", pmcid = "PMC2229050" } @article{https://resolver.caltech.edu/CaltechAUTHORS:KARpnas91, title = "Heterologously expressed serotonin 1A receptors couple to muscarinic K+ channels in heart", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:KARpnas91", id = "record", issn = "0027-8424", doi = "10.1073/pnas.88.13.5694", volume = "88", pmcid = "PMC51944" } @article{https://resolver.caltech.edu/CaltechAUTHORS:AHMnar90, title = "Both sodium channel II and IIA alpha subunits are expressed in rat brain", journal = "Nucleic Acids Research", url = "https://resolver.caltech.edu/CaltechAUTHORS:AHMnar90", id = "record", issn = "0305-1048", doi = "10.1093/nar/18.19.5907", volume = "18", pmcid = "PMC332354" } @article{https://resolver.caltech.edu/CaltechAUTHORS:KRAjgp90, title = "Inactivation of cloned Na channels expressed in Xenopus oocytes", journal = "Journal of General Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:KRAjgp90", id = "record", issn = "0022-1295", doi = "10.1085/jgp.96.4.689", volume = "96", pmcid = "PMC2229013" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20141222-150126708, title = "Cloning and expression of a rat brain GABA transporter", journal = "Science", url = "https://resolver.caltech.edu/CaltechAUTHORS:20141222-150126708", id = "record", issn = "0036-8075", doi = "10.1126/science.1975955", volume = "249" } @article{https://resolver.caltech.edu/CaltechAUTHORS:SNUpnas90, title = "Rat brain expresses a heterogeneous family of calcium channels", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:SNUpnas90", id = "record", issn = "0027-8424", doi = "10.1073/pnas.87.9.3391", volume = "87", pmcid = "PMC53906" } @article{https://resolver.caltech.edu/CaltechAUTHORS:AULpnas90, title = "A Neutral Amino Acid Change in Segment IIS4 Dramatically Alters the Gating Properties of the Voltage-Dependent Sodium Channel", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:AULpnas90", id = "record", issn = "0027-8424", volume = "87", pmcid = "PMC53255" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20170408-161145019, title = "An open-channel blocker interacts with adjacent turns of α-helices in the nicotinic acetylcholine receptor", journal = "Neuron", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170408-161145019", id = "record", issn = "0896-6273", doi = "10.1016/0896-6273(90)90445-L", volume = "4" } @article{https://resolver.caltech.edu/CaltechAUTHORS:YULjbc89, title = "Functional expression of the yeast alpha-factor receptor in Xenopus oocytes", journal = "Journal of Biological Chemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:YULjbc89", id = "record", issn = "0021-9258", volume = "264" } @article{https://resolver.caltech.edu/CaltechAUTHORS:LEOpnas89, title = "Expression of Drosophila Shaker potassium channels in mammalian cells infected with recombinant vaccinia virus", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:LEOpnas89", id = "record", issn = "0027-8424", volume = "86", pmcid = "PMC298120" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201012-160322461, title = "Expression of mRNA Encoding Voltage-Dependent Ca Channels in Xenopus Oocytes: Review and Progress Report", journal = "Annals of the New York Academy of Sciences", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201012-160322461", id = "record", issn = "0077-8923", doi = "10.1111/j.1749-6632.1989.tb24094.x", volume = "560" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201012-160322367, title = "Expression of functional sodium channels in stage II–III Xenopus oocytes", journal = "Journal of Neuroscience Methods", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201012-160322367", id = "record", issn = "0165-0270", doi = "10.1016/0165-0270(89)90118-0", volume = "26" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201012-122452479, title = "Further evidence demonstrating that N-methyl-D-aspartate and kainate activate distinct ion channels", journal = "Synapse", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201012-122452479", id = "record", issn = "0887-4476", doi = "10.1002/syn.890040110", volume = "4" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20150128-145454703, title = "Evidence that the M2 membrane-spanning region lines the ion channel pore of the nicotinic receptor", journal = "Science", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150128-145454703", id = "record", issn = "0036-8075", doi = "10.1126/science.2462281", volume = "242" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201013-140643992, title = "At least two mRNA species contribute to the properties of rat brain A-type potassium channel expressed in xenopus oocytes", journal = "Neuron", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201013-140643992", id = "record", issn = "0896-6273", doi = "10.1016/0896-6273(88)90164-x", volume = "1" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20141222-150346710, title = "Heterologous Expression of Excitability Proteins: Route to More Specific Drugs?", journal = "Science", url = "https://resolver.caltech.edu/CaltechAUTHORS:20141222-150346710", id = "record", issn = "0036-8075", doi = "10.1126/science.2457947", volume = "241" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20191104-094627196, title = "Evidence for the involvement of more than one mRNA species in controlling the inactivation process of rat and rabbit brain Na channels expressed in Xenopus oocytes", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20191104-094627196", id = "record", issn = "0270-6474", doi = "10.1523/jneurosci.08-08-02859.1988", volume = "8", pmcid = "PMC6569391" } @article{https://resolver.caltech.edu/CaltechAUTHORS:IVEpnas88b, title = "A-Type Potassium Channels Expressed from Shaker Locus cDNA", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:IVEpnas88b", id = "record", issn = "0027-8424", volume = "85", pmcid = "PMC281833" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201013-140644253, title = "A rat brain Na⁺ channel α subunit with novel gating properties", journal = "Neuron", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201013-140644253", id = "record", issn = "0896-6273", doi = "10.1016/0896-6273(88)90176-6", volume = "1" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201013-140644398, title = "Tetrodotoxin-sensitive voltage-dependent Na currents recorded from Xenopus oocytes injected with mammalian cardiac muscle RNA", journal = "Molecular Brain Research", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201013-140644398", id = "record", issn = "0169-328X", doi = "10.1016/0169-328x(88)90065-4", volume = "3" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201020-070235564, title = "Properties of two classes of rat brain acidic amino acid receptors induced by distinct mRNA populations in Xenopus oocytes", journal = "Synapse", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201020-070235564", id = "record", issn = "0887-4476", doi = "10.1002/syn.890020613", volume = "2" } @inbook{https://resolver.caltech.edu/CaltechAUTHORS:20201014-153713952, title = "The Calcium Channel: Structure, Function and Implications", chapter = "Expression of mRNA Encoding Rat Brain Ca²⁺ Channels in Xenopus Oocytes", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201014-153713952", id = "record", isbn = "9783540500612", doi = "10.1007/978-3-642-73914-9\_22" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120622-143923786, title = "Equilibrium Properties of Mouse-Torpedo Acetylcholine Receptor Hybrids Expressed in Xenopus Oocytes", journal = "Journal of General Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120622-143923786", id = "record", issn = "0022-1295", doi = "10.1085/jgp.90.4.553", volume = "90", pmcid = "PMC2228871" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201013-140644515, title = "Expression of mouse-Torpedo acetylcholine receptor subunit chimeras and hybrids in Xenopus oocytes", journal = "Molecular Brain Research", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201013-140644515", id = "record", issn = "0169-328X", doi = "10.1016/0169-328x(87)90026-x", volume = "2" } @article{https://resolver.caltech.edu/CaltechAUTHORS:LUBpnas87, title = "cDNA Cloning of a Serotonin 5-HT1C Receptor by Electrophysiological Assays of mRNA-Injected Xenopus Oocytes", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:LUBpnas87", id = "record", issn = "0027-8424", volume = "84", pmcid = "PMC305079" } @article{https://resolver.caltech.edu/CaltechAUTHORS:GURpnas87, title = "Activation of a Potassium Current by Rapid Photochemically Generated Step Increases of Intracellular Calcium in Rat Sympathetic Neurons", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:GURpnas87", id = "record", issn = "0027-8424", volume = "84", pmcid = "PMC304898" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201013-140644623, title = "Light-flash physiology with synthetic photosensitive compounds", journal = "Physiological Reviews", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201013-140644623", id = "record", issn = "0031-9333", doi = "10.1152/physrev.1987.67.2.583", volume = "67" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201013-145241211, title = "Rat brain 5-HT\_(1C) receptors are encoded by a 5-6 kbase mRNA size class and are functionally expressed in injected Xenopus oocytes", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201013-145241211", id = "record", issn = "0270-6474", doi = "10.1523/jneurosci.07-04-01159.1987", volume = "7", pmcid = "PMC6569006" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201013-145241336, title = "Ca channels induced in Xenopus oocytes by rat brain mRNA", journal = "Journal of Neuroscience", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201013-145241336", id = "record", issn = "0270-6474", doi = "10.1523/jneurosci.07-03-00875.1987", volume = "7", pmcid = "PMC6569056" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201009-153923021, title = "Characterization of voltage-gated calcium channels in Xenopus oocytes after injection of RNA from electrically excitable tissues", journal = "Society of General Physiologists series", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201009-153923021", id = "record", issn = "0094-7733", volume = "42" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201012-152225953, title = "Involvement of a GTP-binding protein in mediation of serotonin and acetylcholine responses in Xenopus oocytes injected with rat brain messenger RNA", journal = "Molecular Brain Research", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201012-152225953", id = "record", issn = "0169-328X", doi = "10.1016/0169-328x(86)90026-4", volume = "1" } @article{https://resolver.caltech.edu/CaltechAUTHORS:GOLpnas86, title = "Messenger RNA coding for only the alpha subunit of the rat brain Na channel is sufficient for expression of functional channels in Xenopus oocytes", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:GOLpnas86", id = "record", issn = "0027-8424", volume = "83", pmcid = "PMC386747" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201012-152226105, title = "Activation of acetylcholine receptor channels by covalently bound agonists in cultured rat myoballs", journal = "Journal of Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201012-152226105", id = "record", issn = "0022-3751", doi = "10.1113/jphysiol.1986.sp016242", volume = "379", pmcid = "PMC1182886" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201012-152226204, title = "Expression and modulation of voltage-gated calcium channels after RNA injection in Xenopus oocytes", journal = "Science", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201012-152226204", id = "record", issn = "0036-8075", doi = "10.1126/science.2418503", volume = "231" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201012-152226305, title = "Dose-response of acetylcholine receptor channels opened by a flash-activated agonist in voltage-clamped rat myoballs", journal = "Journal of Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201012-152226305", id = "record", issn = "0022-3751", doi = "10.1113/jphysiol.1986.sp015983", volume = "371", pmcid = "PMC1192732" } @article{https://resolver.caltech.edu/CaltechAUTHORS:DASpnas85, title = "Acetylcholine and phorbol esters inhibit potassium currents evoked by adenosine and cAMP in Xenopus oocytes", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:DASpnas85", id = "record", issn = "0027-8424", volume = "82", pmcid = "PMC390682" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120629-070830645, title = "Photoinduced Removal of Nifedipine Reveals Mechanisms of Calcium Antagonist Action on Single Heart Cells", journal = "Journal of General Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120629-070830645", id = "record", issn = "0022-1295", doi = "10.1085/jgp.86.3.353", volume = "86", pmcid = "PMC2228798" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120628-075949869, title = "Rates and Equilibria for a Photoisomerizable Antagonist at the Acetylcholine Receptor of Electrophorus Electroplaques", journal = "Journal of General Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120628-075949869", id = "record", issn = "0022-1295", doi = "10.1085/jgp.86.2.235", volume = "86", pmcid = "PMC2228782" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201012-152226405, title = "Photoactivation and dissociation of agonist molecules at the nicotinic acetylcholine receptor in voltage-clamped rat myoballs", journal = "Biophysical Journal", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201012-152226405", id = "record", issn = "0006-3495", doi = "10.1016/s0006-3495(85)83777-2", volume = "48", pmcid = "PMC1329315" } @article{https://resolver.caltech.edu/CaltechAUTHORS:WHIpnas85, title = "Mouse-Torpedo Hybrid Acetylcholine Receptors: Functional Homology Does not Equal Sequence Homology", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:WHIpnas85", id = "record", issn = "0027-8424", volume = "82", pmcid = "PMC391003" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201020-073939931, title = "Photochemically produced intracellular concentration jumps of cAMP mimic the effects of catecholamines on excitation-contraction coupling in frog atrial fibers", journal = "Pflügers Archiv European Journal of Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201020-073939931", id = "record", issn = "0031-6768", doi = "10.1007/bf00583606", volume = "403" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201012-152226500, title = "Software for electrophysiological experiments with a personal computer", journal = "Journal of Neuroscience Methods", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201012-152226500", id = "record", issn = "0165-0270", doi = "10.1016/0165-0270(85)90016-0", volume = "12" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201012-160322096, title = "New photoactivatable cyclic nucleotides produce intracellular jumps in cyclic AMP and cyclic GMP concentrations", journal = "Nature", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201012-160322096", id = "record", issn = "0028-0836", doi = "10.1038/310074a0", volume = "310" } @article{https://resolver.caltech.edu/CaltechAUTHORS:NARpnas83, title = "Time Course of the Increase in the Myocardial Slow Inward Current after a Photochemically Generated Concentration Jump of Intracellular cAMP", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:NARpnas83", id = "record", issn = "0027-8424", volume = "80", pmcid = "PMC393827" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201012-160244665, title = "cis-3,3'-Bis-[α-(trimethylammonium)methyl]azobenzene (cis-Bis-Q). Purification and properties at acetylcholine receptors of Electrophorus electroplaques", journal = "Molecular pharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201012-160244665", id = "record", issn = "0026-895X", volume = "23" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201020-074502837, title = "Activation and inhibition of adenylate cyclase by hormones", journal = "Biochemical Society Transactions", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201020-074502837", id = "record", issn = "0300-5127", doi = "10.1042/bst0100496", volume = "10" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120717-113744311, title = "Functional Stoichiometry at the Nicotinic Receptor. The Photon Cross Section for Phase 1 Corresponds to Two Bis-Q Molecules per Channel", journal = "Journal of General Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120717-113744311", id = "record", issn = "0022-1295", doi = "10.1085/jgp.80.4.499", volume = "80", pmcid = "PMC2228709" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120717-132820326, title = "Physiological and Pharmacological Manipulations with Light Flashes", journal = "Annual Review of Biophysics and Bioengineering", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120717-132820326", id = "record", issn = "0084-6589", doi = "10.1146/annurev.bb.11.060182.001055", volume = "11" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201012-160322257, title = "ADP-Ribosylation of Membrane Proteins in Cholinergic Nerve Terminals", journal = "Journal of Neurochemistry", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201012-160322257", id = "record", issn = "0022-3042", doi = "10.1111/j.1471-4159.1982.tb05351.x", volume = "38" } @article{https://resolver.caltech.edu/CaltechAUTHORS:NARjgp82, title = "A photoisomerizable muscarinic antagonist. Studies of binding and of conductance relaxations in frog heart", journal = "Journal of General Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:NARjgp82", id = "record", issn = "0022-1295", doi = "10.1085/jgp.79.4.657", volume = "79", pmcid = "PMC2215484" } @article{https://resolver.caltech.edu/CaltechAUTHORS:LESpnas82, title = "Prostaglandin-Stimulated GTP Hydrolysis Associated with Activation of Adenylate Cyclase in Human Platelet Membranes", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:LESpnas82", id = "record", issn = "0027-8424", volume = "79", pmcid = "PMC345823" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201009-153010808, title = "Activation of adenylate cyclase from purified platelet membranes by prostaglandin E1 and its inhibition by L-epinephrine: mechanistic effects", journal = "Journal of Cyclic Nucleotide Research", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201009-153010808", id = "record", issn = "0095-1544", volume = "8" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201005-113706566, title = "A potpourri of plucked patches", journal = "Nature", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201005-113706566", id = "record", issn = "0028-0836", doi = "10.1038/294398a0", volume = "294" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201005-113706477, title = "Electrophysiological Experiments With Photoisomerizable Cholinergic Compounds: Review and Progress Report", journal = "Annals of the New York Academy of Sciences", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201005-113706477", id = "record", issn = "0077-8923", doi = "10.1111/j.1749-6632.1980.tb22118.x", volume = "346" } @article{https://resolver.caltech.edu/CaltechAUTHORS:LESjgp80, title = "A covalently bound photoisomerizable agonist. Comparison with reversibly bound agonists at electrophorus electroplaques", journal = "Journal of General Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:LESjgp80", id = "record", issn = "0022-1295", doi = "10.1085/jgp.75.2.207", volume = "75", pmcid = "PMC2215740" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201005-113706376, title = "The kinetics of tubocurarine action and restricted diffusion within the synaptic cleft", journal = "Journal of Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201005-113706376", id = "record", issn = "0022-3751", doi = "10.1113/jphysiol.1979.sp012935", volume = "294", pmcid = "PMC1280562" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201005-113706274, title = "Light-activated drug confirms a mechanism of ion channel blockade", journal = "Nature", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201005-113706274", id = "record", issn = "0028-0836", doi = "10.1038/280509a0", volume = "280" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201005-113706172, title = "Numerical reconstruction of the quantal event at nicotinic synapses", journal = "Biophysical Journal", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201005-113706172", id = "record", issn = "0006-3495", doi = "10.1016/s0006-3495(79)85208-x", volume = "27", pmcid = "PMC1328553" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201005-113630529, title = "Voltage-dependent and voltage-independent blockade of acetylcholine receptors by local anesthetics in Electrophorus electroplaques", journal = "Molecular Pharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201005-113630529", id = "record", issn = "0026-895X", volume = "15" } @article{https://resolver.caltech.edu/CaltechAUTHORS:LESjgp78, title = "Analysis of sodium and potassium redistribution during sustained permeability increases at the innervated face of Electrophorus electroplaques", journal = "Journal of General Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:LESjgp78", id = "record", issn = "0022-1295", doi = "10.1085/jgp.72.6.847", volume = "72", pmcid = "PMC2228490" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201005-113706084, title = "Response of acetylcholine receptors to photoisomerizations of bound agonist molecules", journal = "Biophysical Journal", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201005-113706084", id = "record", issn = "0006-3495", doi = "10.1016/s0006-3495(78)85352-1", volume = "24", pmcid = "PMC1473870" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201005-113705979, title = "Role of voltage-sensitive receptors in nicotinic transmission", journal = "Biophysical Journal", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201005-113705979", id = "record", issn = "0006-3495", doi = "10.1016/s0006-3495(78)85518-0", volume = "21", pmcid = "PMC1473691" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20120119-120416762, title = "Rates and equilibria at the acetylcholine receptor of electrophorus electroplaques. A study of neurally evoked postsynaptic currents and of voltage-jump relaxations", journal = "Journal of General Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120119-120416762", id = "record", issn = "0022-1295", doi = "10.1085/jgp.70.2.187", volume = "70", pmcid = "PMC2228462" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201005-113705890, title = "Response of acetylcholine receptors to rapid photochemically produced increases in agonist concentration", journal = "Nature", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201005-113705890", id = "record", issn = "0028-0836", doi = "10.1038/266373a0", volume = "266" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201005-113705797, title = "The response to acetylcholine", journal = "Scientific American", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201005-113705797", id = "record", issn = "0036-8733", doi = "10.1038/scientificamerican0277-106", volume = "236" } @article{https://resolver.caltech.edu/CaltechAUTHORS:SHEpnas75, title = "Relaxation measurements on the acetylcholine receptor", journal = "Proceedings of the National Academy of Sciences of the United States of America", url = "https://resolver.caltech.edu/CaltechAUTHORS:SHEpnas75", id = "record", issn = "0027-8424", doi = "10.1073/pnas.72.9.3496", volume = "72", pmcid = "PMC433021" } @article{https://resolver.caltech.edu/CaltechAUTHORS:LESjgp75, title = "Conductance increases produced by bath application of cholinergic agonists to Electrophorus electroplaques", journal = "Journal of General Physiology", url = "https://resolver.caltech.edu/CaltechAUTHORS:LESjgp75", id = "record", issn = "0022-1295", doi = "10.1085/jgp.65.6.797", volume = "65", pmcid = "PMC2214893" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201005-113628628, title = "Blockade of acetylcholine receptors by cobra toxin: electrophysiological studies", journal = "Molecular Pharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201005-113628628", id = "record", issn = "0026-895X", volume = "8" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201005-113629507, title = "Vulnerability of desensitized or curare-treated acetylcholine receptors to irreversible blockade by cobra toxin", journal = "Molecular Pharmacology", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201005-113629507", id = "record", issn = "0026-895X", volume = "8" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201005-113705712, title = "Postsynaptic Action of Cobra Toxin at the Myoneural Junction", journal = "Nature", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201005-113705712", id = "record", issn = "0028-0836", doi = "10.1038/227727a0", volume = "227" } @article{https://resolver.caltech.edu/CaltechAUTHORS:20201005-113705571, title = "Transmitter Release by Presynaptic Impulses in the Squid Stellate Ganglion", journal = "Nature", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201005-113705571", id = "record", issn = "0028-0836", doi = "10.1038/227493a0", volume = "227" }