Griffin, Matthew E.; Hsieh-Wilson, Linda C. (2022) Tools for mammalian glycoscience research Cell; (In Press)
Ramadan, Sherif; Su, Guowei et al. (2022) Automated solid phase assisted synthesis of a heparan sulfate disaccharide library Organic Chemistry Frontiers; Vol. 9; No. 11;
Hsieh-Wilson, Linda (2021) Chondroitin 4-O-sulfation regulates hippocampal perineuronal nets and synaptic plasticity Glycobiology; Vol. 31; No. 12; 2021 Annual Meeting of the Society for Glycobiology, 7-10 November 2021 , San Diego, CA
Griffin, Matthew E.; Sorum, Alexander W. et al. (2021) Sulfated glycans engage the Ang–Tie pathway to regulate vascular development Nature Chemical Biology; Vol. 17; No. 2;
Joffrin, Amélie M.; Hsieh-Wilson, Linda C. (2020) Photoaffinity Probes for the Identification of Sequence-Specific Glycosaminoglycan-Binding Proteins Journal of the American Chemical Society; Vol. 142; No. 32;
Pawar, Nitin J.; Wang, Lei et al. (2019) Expedient Synthesis of Core Disaccharide Building Blocks from Natural Polysaccharides for Heparan Sulfate Oligosaccharide Assembly Angewandte Chemie International Edition; Vol. 58; No. 51;
Liu, Liang-Chih; Wang, Yuan-Liang et al. (2019) Long non-coding RNA HOTAIR promotes invasion of breast cancer cells through chondroitin sulfotransferase CHST15 International Journal of Cancer; Vol. 145; No. 9;
Liu, Liang‐Chih; Wang, Yuan‐Liang et al. (2019) Long noncoding RNA HOTAIR promotes invasion of breast cancer cells through chondroitin sulfotransferase CHST15 International Journal of Cancer; Vol. 145; No. 9;
Li, Xuexia; Zhu, Qiang et al. (2019) O-GlcNAcylation of core components of the translation initiation machinery regulates protein synthesis Proceedings of the National Academy of Sciences of the United States of America; Vol. 116; No. 16;
Li, Jingchao; Li, Zhonghua et al. (2019) An Isotope-Coded Photocleavable Probe for Quantitative Profiling of Protein O-GlcNAcylation ACS Chemical Biology; Vol. 14; No. 1;
Darabedian, Narek; Thompson, John W. et al. (2018) Optimization of chemoenzymatic mass-tagging by strain-promoted cycloaddition (SPAAC) for the determination of O-GlcNAc stoichiometry by Western blotting Biochemistry; Vol. 57; No. 40;
Stopschinski, Barbara E.; Holmes, Brandon B. et al. (2018) Specific Glycosaminoglycan Chain Length and Sulfation Patterns Are Required for Cell Uptake of Tau vs. α-Synuclein and β-Amyloid Aggregates Annals of Neurology; Vol. 84; No. S22; 143rd Annual Meeting of the American-Neurological-Association (ANA), 21-23 October 2018 , Atlanta, GA
Hsieh-Wilson, Linda C. (2018) A Molecular Window into the Brain: Special Issue on Molecules and the Brain Biochemistry; Vol. 57; No. 27;
Thompson, John W.; Sorum, Alexander W. et al. (2018) Deciphering the functions of O-GlcNAc glycosylation in the brain: The role of site-specific quantitative O-GlcNAcomics Biochemistry; Vol. 57; No. 27;
Stopschinski, Barbara E.; Holmes, Brandon B. et al. (2018) Specific glycosaminoglycan chain length and sulfation patterns are required for cell uptake of tau versus α-synuclein and β-amyloid aggregates Journal of Biological Chemistry; Vol. 293; No. 27;
Rauch, Jennifer N.; Chen, John J. et al. (2018) Tau Internalization is Regulated by 6-O Sulfation on Heparan Sulfate Proteoglycans (HSPGs) Scientific Reports; Vol. 8;
Matho, Michael H.; Schlossman, Andrew et al. (2018) Structure-function characterization of three human antibodies targeting the vaccinia virus adhesion molecule D8 Journal of Biological Chemistry; Vol. 293; No. 1;
Thompson, John W.; Griffin, Matthew E. et al. (2018) Methods for the Detection, Study, and Dynamic Profiling of O-GlcNAc Glycosylation Chemical Glycobiology Part B. Monitoring Glycans and their Interactions; Methods in Enzymology; Vol. 598;
Griffith, Adam R.; Rogers, Claude J. et al. (2017) Predicting glycosaminoglycan surface protein interactions and implications for studying axonal growth Proceedings of the National Academy of Sciences of the United States of America; Vol. 114; No. 52;
Cheung, Sheldon T.; Miller, Michelle S. et al. (2017) Discovery of a Small-Molecule Modulator of Glycosaminoglycan Sulfation ACS Chemical Biology; Vol. 12; No. 12;
Wang, Andrew C.; Jensen, Elizabeth H. et al. (2016) Loss of O-GlcNAc glycosylation in forebrain excitatory neurons induces neurodegeneration Proceedings of the National Academy of Sciences of the United States of America; Vol. 113; No. 52;
Griffin, Matthew E.; Jensen, Elizabeth H. et al. (2016) Comprehensive mapping of O-GlcNAc modification sites using a chemically cleavable tag Molecular BioSystems; Vol. 12; No. 6;
Griffin, Matthew E.; Hsieh-Wilson, Linda C. (2016) Glycan Engineering for Cell and Developmental Biology Cell Chemical Biology; Vol. 23; No. 1;
Miller, Gregory M.; Hsieh-Wilson, Linda C. (2015) Sugar-Dependent Modulation of Neuronal Development, Regeneration, and Plasticity by Chondroitin Sulfate Proteoglycans Experimental Neurology; Vol. 274; No. B;
Hsieh-Wilson, Linda C. (2015) Carbohydrate signaling in the brain Abstracts of Papers of the American Chemical Society; Vol. 249; 249th American Chemical Society National Meeting & Exposition, March 22-26, 2015 , Denver, CO
Pulsipher, Abigail; Griffin, Matthew E. et al. (2015) Long-Lived Engineering of Glycans to Direct Stem Cell Fate Angewandte Chemie International Edition; Vol. 54; No. 5;
Matho, Michael H.; de Val, Natalia et al. (2014) Murine Anti-vaccinia Virus D8 Antibodies Target Different Epitopes and Differ in Their Ability to Block D8 Binding to CS-E PLoS Pathogens; Vol. 10; No. 12;
Wibowo, Arif; Peters, Eric C. et al. (2014) Photoactivatable Glycopolymers for the Proteome-Wide Identification of Fucose-α(1-2)-Galactose Binding Proteins Journal of the American Chemical Society; Vol. 136; No. 27;
Pulsipher, Abigail; Griffin, Matthew E. et al. (2014) Directing Neuronal Signaling through Cell-Surface Glycan Engineering Journal of the American Chemical Society; Vol. 136; No. 19;
Hsieh-Wilson, Linda C.; Griffin, Matthew E. (2013) Improving Biologic Drugs via Total Chemical Synthesis Science; Vol. 342; No. 6164;
Griffin, Matthew E.; Hsieh-Wilson, Linda C. (2013) Synthetic probes of glycosaminoglycan function Current Opinion in Chemical Biology; Vol. 17; No. 6;
Clark, Peter M.; Rexach, Jessica E. et al. (2013) Visualization of O-GlcNAc Glycosylation Stoichiometry and Dynamics Using Resolvable Poly(ethylene glycol) Mass Tags Current Protocols in Chemical Biology; Vol. 5;
Oh, Young In; Sheng, Gloria J. et al. (2013) Tailored Glycopolymers as Anticoagulant Heparin Mimetics Angewandte Chemie International Edition; Vol. 52; No. 45;
Dick, Gunnar; Tan, Chin Lik et al. (2013) Semaphorin 3A Binds to the Perineuronal Nets via Chondroitin Sulfate Type E Motifs in Rodent Brains Journal of Biological Chemistry; Vol. 288; No. 38;
Ramakrishnan, Parameswaran; Clark, Peter M. et al. (2013) Activation of the Transcriptional Function of the NF-κB Protein c-Rel by O-GlcNAc Glycosylation Science Signaling; Vol. 6; No. 290;
Sheng, Gloria J.; Oh, Young In et al. (2013) Tunable Heparan Sulfate Mimetics for Modulating Chemokine Activity Journal of the American Chemical Society; Vol. 135; No. 30;
Hsieh-Wilson, Linda C. (2013) O-GlcNAc Signaling Regulates Cancer Metabolism FASEB Journal; Vol. 27; Joint Annual Meeting of the ASPET/BPS at Experimental Biology (EB), April 20-24, 2013 , Boston, MA
Yi, Wen; Clark, Peter M. et al. (2012) Phosphofructokinase 1 Glycosylation Regulates Cell Growth and Metabolism Science; Vol. 337; No. 6097;
Brown, Joshua M.; Xia, Jiang et al. (2012) A sulfated carbohydrate epitope inhibits axon regeneration after injury Proceedings of the National Academy of Sciences of the United States of America; Vol. 109; No. 13;
Chaubard, Jean-Luc; Krishnamurthy, Chithra et al. (2012) Chemoenzymatic Probes for Detecting and Imaging Fucose-α(1-2)-galactose Glycan Biomarkers Journal of the American Chemical Society; Vol. 134; No. 10;
Rexach, Jessica E.; Clark, Peter M. et al. (2012) Dynamic O-GlcNAc modification regulates CREB-mediated gene expression and memory formation Nature Chemical Biology; Vol. 8; No. 3;
Rogers, Claude J.; Clark, Peter M. et al. (2011) Elucidating glycosaminoglycan–protein–protein interactions using carbohydrate microarray and computational approaches Proceedings of the National Academy of Sciences of the United States of America; Vol. 108; No. 24;
Lee, Song-Gil; Brown, Joshua M. et al. (2010) End-functionalized glycopolymers as mimetics of chondroitin sulfate proteoglycans Chemical Science; Vol. 1; No. 3;
Rexach, Jessica E.; Rogers, Claude J. et al. (2010) Quantification of O-glycosylation stoichiometry and dynamics using resolvable mass tags Nature Chemical Biology; Vol. 6; No. 9;
Murrey, Heather E.; Ficarro, Scott B. et al. (2009) Identification of the Plasticity-Relevant Fucose-α(1−2)-Galactose Proteome from the Mouse Olfactory Bulb Biochemistry; Vol. 48; No. 30;
Wang, Zihao; Park, Kyoungsook et al. (2009) Site-Specific GlcNAcylation of Human Erythrocyte Proteins Potential Biomarker(s) for Diabetes Diabetes; Vol. 58; No. 2;
Clark, Peter M.; Dweck, Jessica F. et al. (2008) Direct in-gel fluorescence detection and cellular imaging of O-GlcNAc-modified proteins Journal of the American Chemical Society; Vol. 130; No. 35;
Murrey, Heather E.; Hsieh-Wilson, Linda C. (2008) The Chemical Neurobiology of Carbohydrates Chemical Reviews; Vol. 108; No. 5;
Rawat, Manish; Gama, Cristal I. et al. (2008) Neuroactive chondroitin sulfate glycomimetics Journal of the American Chemical Society; Vol. 130; No. 10;
Rexach, Jessica E.; Clark, Peter M. et al. (2008) Chemical approaches to understanding O-GlcNAc glycosylation in the brain Nature Chemical Biology; Vol. 4; No. 2;
Sotogaku, Naoki; Tully, Sarah E. et al. (2007) Activation of phospholipase C pathways by a synthetic chondroitin sulfate-E tetrasaccharide promotes neurite outgrowth of dopaminergic neurons Journal of Neurochemistry; Vol. 103; No. 2;
Khidekel, Nelly; Ficarro, Scott B. et al. (2007) Probing the dynamics of O-GlcNAc glycosylation in the brain using quantitative proteomics Nature Chemical Biology; Vol. 3; No. 6;
Boeggeman, Elizabeth; Ramakrishnan, Boopathy et al. (2007) Direct identification of nonreducing GlcNAc residues on N-glycans of glycoproteins using a novel chemoenzymatic method Bioconjugate Chemistry; Vol. 18; No. 3;
Shipp, Eric L.; Hsieh-Wilson, Linda C. (2007) Profiling the sulfation specificities of glycosaminoglycan interactions with growth factors and chemotactic proteins using microarrays Chemistry and Biology; Vol. 14; No. 2;
Hsieh-Wilson, Linda C. (2007) Bioorganic Chemistry: A Sweet Synthesis Nature; Vol. 445; No. 7123;
Gama, Cristal I.; Tully, Sarah E. et al. (2006) Sulfation patterns of glycosaminoglycans encode molecular recognition and activity Nature Chemical Biology; Vol. 2; No. 9;
Tully, Sarah E.; Rawat, Manish et al. (2006) Discovery of a TNF-α Antagonist Using Chondroitin Sulfate Microarrays Journal of the American Chemical Society; Vol. 128; No. 24;
Murrey, Heather E.; Gama, Cristal I. et al. (2006) Protein fucosylation regulates synapsin Ia/Ib expression and neuronal morphology in primary hippocampal neurons Proceedings of the National Academy of Sciences of the United States of America; Vol. 103; No. 1;
Gama, Cristal I.; Hsieh-Wilson, Linda C. (2005) Chemical approaches to deciphering the glycosaminoglycan code Current Opinion in Chemical Biology; Vol. 9; No. 6;
Uematsu, Ken; Futter, Marie et al. (2005) Regulation of spinophilin Ser94 phosphorylation in neostriatal neurons involves both DARPP-32-dependent and independent pathways Journal of Neurochemistry; Vol. 95; No. 6;
Kalovidouris, Stacey A.; Gama, Cristal I. et al. (2005) A Role for Fucose α(1−2) Galactose Carbohydrates in Neuronal Growth Journal of the American Chemical Society; Vol. 127; No. 5;
Hsieh-Wilson, Linda C. (2004) Tailor-made glycoproteins Trends in Biotechnology; Vol. 22; No. 10;
Khidekel, Nelly; Ficarro, Scott B. et al. (2004) Exploring the O-GlcNAc proteome: Direct identification of O-GlcNAc-modified proteins from the brain Proceedings of the National Academy of Sciences of the United States of America; Vol. 101; No. 36;
Tai, Hwan-Ching; Khidekel, Nelly et al. (2004) Parallel identification of O-GlcNAc-modified proteins from cell lysates Journal of the American Chemical Society; Vol. 126; No. 34;
Grossman, Stacie D.; Futter, Marie et al. (2004) Spinophilin is phosphorylated by Ca^(2+)/calmodulin-dependent protein kinase II resulting in regulation of its binding to F-actin Journal of Neurochemistry; Vol. 90; No. 2;
Tully, Sarah E.; Mabon, Ross et al. (2004) A chondroitin sulfate small molecule that stimulates neuronal growth Journal of the American Chemical Society; Vol. 126; No. 25;
Khidekel, Nelly; Hsieh-Wilson, Linda C. (2004) A 'molecular switchboard' - covalent modifications to proteins and their impact on transcription Organic and Biomolecular Chemistry; Vol. 2; No. 1;
Khidekel, Nelly; Arndt, Sabine et al. (2003) A Chemoenzymatic Approach toward the Rapid and Sensitive Detection of O-GlcNAc Posttranslational Modifications Journal of the American Chemical Society; Vol. 125; No. 52;
Arndt, Sabine; Hsieh-Wilson, Linda C. (2003) Use of Cerny epoxides for the accelerated synthesis of glycosaminoglycans Organic Letters; Vol. 5; No. 22;
Lamarre-Vincent, Nathan; Hsieh-Wilson, Linda C. (2003) Dynamic glycosylation of the transcription factor CREB: A potential role in gene regulation Journal of the American Chemical Society; Vol. 125; No. 22;
Hsieh-Wilson, Linda C.; Benfenati, Fabio et al. (2003) Phosphorylation of Spinophilin Modulates Its Interaction with Actin Filaments Journal of Biological Chemistry; Vol. 278; No. 2;
Grossman, Stacie D.; Hsieh-Wilson, Linda C. et al. (2002) The actin-binding domain of spinophilin is necessary and sufficient for targeting to dendritic spines NeuroMolecular Medicine; Vol. 2; No. 1;
Watanabe, Takuo; Huang, Hsien-Bin et al. (2001) Protein phosphatase 1 regulation by inhibitors and targeting subunits Proceedings of the National Academy of Sciences of the United States of America; Vol. 98; No. 6;
Allen, P. B.; Hsieh-Wilson, Linda C. et al. (1999) Control of protein phosphatase I in the dendrite Biochemical Society Transactions; Vol. 27; No. 4; Colloquium on Membrane Signalling Complexes, 7-9 April 1999 , Glasgow, Scotland
Hsieh-Wilson, Linda C.; Allen, Patrick B. et al. (1999) Characterization of the Neuronal Targeting Protein Spinophilin and Its Interactions with Protein Phosphatase-1 Biochemistry; Vol. 38; No. 14;
Yan, Zhen; Hsieh-Wilson, Linda et al. (1999) Protein phosphatase 1 modulation of neostriatal AMPA channels: regulation by DARPP−32 and spinophilin Nature Neuroscience; Vol. 2; No. 1;
Ma, Lifu; Hsieh-Wilson, Linda C. et al. (1998) Antibody catalysis of peptidyl-prolyl cis-trans isomerization in the folding of RNase T1 Proceedings of the National Academy of Sciences of the United States of America; Vol. 95; No. 13;
Hsieh-Wilson, Linda C.; Schultz, Peter G. et al. (1996) Insights into antibody catalysis: Structure of an oxygenation catalyst at 1.9-Å resolution Proceedings of the National Academy of Sciences of the United States of America; Vol. 93; No. 11;
Hsieh-Wilson, Linda C.; Xiang, Xiao-Dong et al. (1996) Lessons from the immune system: From catalysis to materials science Accounts of Chemical Research; Vol. 29; No. 3;
Stevens, Raymond C.; Hsieh-Wilson, Linda C. et al. (1996) Structural Studies of Catalytic Antibodies Israel Journal of Chemistry; Vol. 36; No. 2;
Hsieh-Wilson, Linda C.; Stephans, James C. et al. (1994) An Efficient Antibody-Catalyzed Oxygenation Reaction Journal of the American Chemical Society; Vol. 116; No. 5;
Yu, Jaehoon; Hsieh-Wilson, Linda C. et al. (1994) Progress toward an Antibody Glycosidase Angewandte Chemie-International Edition In English; Vol. 33; No. 3;
Hsieh-Wilson, Linda C.; Yonkovich, Shirlee et al. (1993) Controlling Chemical Reactivity with Antibodies Science; Vol. 260; No. 5106;