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Christopher and Roxas, Kristina M. and Chan, Ken Y. and Scherrer, Jon and Winchester, Janet and Blackburn, Roy J. and Campos, Lillian J. and Man, Kwun Nok Mimi and Sun, Junqing and Chen, Xinhong and Lefevre, Arthur and Singh, Vikram Pal and Arokiaraj, Cynthia M. and Shay, Timothy F. and Vendemiatti, Julia and Jang, Min J. and Mich, John K. and Bishaw, Yemeserach and Gore, Bryan B. and Omstead, Victoria and Taskin, Naz and Weed, Natalie and Levi, Boaz P. and Ting, Jonathan T. and Miller, Cory T. and Deverman, Benjamin E. and Pickel, James and Tian, Lin and Fox, Andrew S. and Gradinaru, Viviana", title = "Adeno-associated viral vectors for functional intravenous gene transfer throughout the non-human primate brain", journal = "Nature Nanotechnology", publisher = "Nature Publishing Group", year = "2023", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230725-857203000.51", id = "https://authors.library.caltech.edu/records/6qa0d-19h32", issn = "1748-3387", doi = "10.1038/s41565-023-01419-x", volume = "18", number = "10", pmcid = "PMC10575780", pages = "1241-1251" } @article{https://authors.library.caltech.edu/records/vytfy-emg42, authors = "Jang, Min J. and Coughlin, Gerard M. and Jackson, Cameron R. and Chen, Xinhong and Chuapoco, Miguel R. and Vendemiatti, Julia L. and Wang, Alexander Z. and Gradinaru, Viviana", title = "Spatial transcriptomics for profiling the tropism of viral vectors in tissues", journal = "Nature Biotechnology", publisher = "Nature Publishing Group", year = "2023", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230301-701033500.22", id = "https://authors.library.caltech.edu/records/vytfy-emg42", issn = "1087-0156", doi = "10.1038/s41587-022-01648-w", volume = "41", number = "9", pmcid = "PMC10443732", pages = "1272-1286" } @article{https://authors.library.caltech.edu/records/6g99y-t0377, authors = "Chen, Xinhong and Wolfe, Damien A. and Bindu, Dhanesh Sivadasan and Zhang, Mengying and Taskin, Naz and Goertsen, David and Shay, Timothy F. and Sullivan, Erin E. and Huang, Sheng-Fu and Ravindra Kumar, Sripriya and Arokiaraj, Cynthia M. and Plattner, Viktor M. and Campos, Lillian J. and Mich, John K. and Monet, Deja and Ngo, Victoria and Ding, Xiaozhe and Omstead, Victoria and Weed, Natalie and Bishaw, Yeme and Gore, Bryan B. and Lein, Ed S. and Akrami, Athena and Miller, Cory T. and Levi, Boaz P. and Keller, Annika and Ting, Jonathan T. and Fox, Andrew S. and Eroglu, Cagla and Gradinaru, Viviana", title = "Functional gene delivery to and across brain vasculature of systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates", journal = "Nature Communications", publisher = "Nature Publishing Group", year = "2023", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230615-129198000.12", id = "https://authors.library.caltech.edu/records/6g99y-t0377", issn = "2041-1723", doi = "10.1038/s41467-023-38582-7", volume = "14", pmcid = "PMC10250345", pages = "Art. No. 3345" } @article{https://authors.library.caltech.edu/records/jsmm1-2ye23, authors = "Jang, Min Jee and Gradinaru, Viviana", title = "Spatial tropism profiling of AAV vectors by ultrasensitive sequential FISH in tissue", journal = "Nature Biotechnology", publisher = "Nature Publishing Group", year = "2023", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230221-20005500.75", id = "https://authors.library.caltech.edu/records/jsmm1-2ye23", issn = "1087-0156", doi = "10.1038/s41587-023-01681-3", pmcid = "PMC9885914" } @article{https://authors.library.caltech.edu/records/rsg2f-2nj92, authors = "Shay, Timothy F. and Sullivan, Erin E. and Ding, Xiaozhe and Chen, Xinhong and Ravindra Kumar, Sripriya and Goertsen, David and Brown, David and Crosby, Anaya and Vielmetter, Jost and Borsos, Mate and Wolfe, Damien A. and Lam, Annie W. and Gradinaru, Viviana", title = "Primate-conserved carbonic anhydrase IV and murine-restricted LY6C1 enable blood-brain barrier crossing by engineered viral vectors", journal = "Science Advances", publisher = "American Association for the Advancement of Science", year = "2023", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230602-251993000.57", id = "https://authors.library.caltech.edu/records/rsg2f-2nj92", issn = "2375-2548", doi = "10.1126/sciadv.adg6618", volume = "9", number = "16", pmcid = "PMC10115422", pages = "Art. No. eadg6618" } @article{https://authors.library.caltech.edu/records/j3b0b-jfb61, authors = "Campos, Lillian J. and Arokiaraj, Cynthia M. and Chuapoco, Miguel R. and Chen, Xinhong and Goeden, Nick and Gradinaru, Viviana and Fox, Andrew S.", title = "Advances in AAV technology for delivering genetically encoded cargo to the nonhuman primate nervous system", journal = "Current Research in Neurobiology", publisher = "Elsevier", year = "2023", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230725-706045000.29", id = "https://authors.library.caltech.edu/records/j3b0b-jfb61", issn = "2665-945X", doi = "10.1016/j.crneur.2023.100086", volume = "4", pmcid = "PMC10313870", pages = "Art. No. 100086" } @article{https://authors.library.caltech.edu/records/c9mfw-wg325, authors = "Schubert, Rajib and Bae, Taegeun and Simic, Branko and Smith, Sheena N. and Park, Seong-Ho and Nagy-Davidescu, Gabriela and Gradinaru, Viviana and Plückthun, Andreas and Hur, Junho K.", title = "CRISPR-clear imaging of melanin-rich B16-derived solid tumors", journal = "Communications Biology", publisher = "Nature Publishing Group", year = "2023", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230525-772152300.6", id = "https://authors.library.caltech.edu/records/c9mfw-wg325", issn = "2399-3642", doi = "10.1038/s42003-023-04614-7", volume = "6", pmcid = "PMC10073193", pages = "Art. No. 370" } @article{https://authors.library.caltech.edu/records/ndk7v-fhz93, authors = "Abdel-Haq, Reem and Schlachetzki, Johannes C. M. and Boktor, Joseph C. and Cantu-Jungles, Thaisa M. and Thron, Taren and Zhang, Mengying and Bostick, John W. and Khazaei, Tahmineh and Chilakala, Sujatha and Morais, Livia H. and Humphrey, Greg and Keshavarzian, Ali and Katz, Jonathan E. and Thomson, Matthew and Knight, Rob and Gradinaru, Viviana and Hamaker, Bruce R. and Glass, Christopher K. and Mazmanian, Sarkis K.", title = "A prebiotic diet modulates microglial states and motor deficits in α-synuclein overexpressing mice", journal = "eLife", publisher = "eLife Sciences Publications", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20221202-906989500.8", id = "https://authors.library.caltech.edu/records/ndk7v-fhz93", issn = "2050-084X", doi = "10.7554/elife.81453", volume = "11", pmcid = "PMC9668333", pages = "Art. No. e81453" } @article{https://authors.library.caltech.edu/records/1w82f-14a30, authors = "Endo, Fumito and Kasai, Atsushi and Soto, Joselyn S. and Yu, Xinzhu and Qu, Zhe and Hashimoto, Hitoshi and Gradinaru, Viviana and Kawaguchi, Riki and Khakh, Baljit S.", title = "Molecular basis of astrocyte diversity and morphology across the CNS in health and disease", journal = "Science", publisher = "American Association for the Advancement of Science", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20221209-478595000.5", id = "https://authors.library.caltech.edu/records/1w82f-14a30", issn = "0036-8075", doi = "10.1126/science.adc9020", volume = "378", number = "6619", pages = "Art. No. adc9020" } @article{https://authors.library.caltech.edu/records/ynwa0-bnv65, authors = "Jang, Seongmin and Shen, Hao K. and Ding, Xiaozhe and Miles, Timothy F. and Gradinaru, Viviana", title = "Structural basis of receptor usage by the engineered capsid AAV-PHP.eB", journal = "Molecular Therapy - Methods \& Clinical Development", publisher = "Cell Press", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220801-544880000", id = "https://authors.library.caltech.edu/records/ynwa0-bnv65", issn = "2329-0501", doi = "10.1016/j.omtm.2022.07.011", volume = "26", pmcid = "PMC9382559", pages = "343-354" } @article{https://authors.library.caltech.edu/records/atz4j-4ag97, authors = "Goertsen, David and Goeden, Nick and Flytzanis, Nicholas C. and Gradinaru, Viviana", title = "Targeting the lung epithelium after intravenous delivery by directed evolution of underexplored sites on the AAV capsid", journal = "Molecular Therapy - Methods \& Clinical Development", publisher = "Cell Press", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220816-373601000", id = "https://authors.library.caltech.edu/records/atz4j-4ag97", issn = "2329-0501", doi = "10.1016/j.omtm.2022.07.010", volume = "26", pmcid = "PMC9372736", pages = "331-342" } @article{https://authors.library.caltech.edu/records/tb77e-ca060, authors = "Seo, Jai Woong and Ajenjo, Javier and Wu, Bo and Robinson, Elise and Raie, Marina Nura and Wang, James and Tumbale, Spencer K. and Buccino, Pablo and Anders, David Alexander and Shen, Bin and Habte, Frezghi G. and Beinat, Corinne and James, Michelle L. and Reyes, Samantha Taylor and Ravindra Kumar, Sripriya and Miles, Timothy F. and Lee, Jason T. and Gradinaru, Viviana and Ferrara, Katherine W.", title = "Multimodal imaging of capsid and cargo reveals differential brain targeting and liver detargeting of systemically-administered AAVs", journal = "Biomaterials", publisher = "Elsevier", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20221116-602375500.16", id = "https://authors.library.caltech.edu/records/tb77e-ca060", issn = "0142-9612", doi = "10.1016/j.biomaterials.2022.121701", volume = "288", pmcid = "PMC9621732", pages = "Art. No. 121701" } @article{https://authors.library.caltech.edu/records/aj0e9-00c08, authors = "Chen, Xinhong and Ravindra Kumar, Sripriya and Adams, Cameron D. and Yang, Daping and Wang, Tongtong and Wolfe, Damien A. and Arokiaraj, Cynthia M. and Ngo, Victoria and Campos, Lillian J. and Griffiths, Jessica A. and Ichiki, Takako and Mazmanian, Sarkis K. and Osborne, Peregrine B. and Keast, Janet R. and Miller, Cory T. and Fox, Andrew S. and Chiu, Isaac M. and Gradinaru, Viviana", title = "Engineered AAVs for non-invasive gene delivery to rodent and non-human primate nervous systems", journal = "Neuron", publisher = "Cell Press", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220606-735990000", id = "https://authors.library.caltech.edu/records/aj0e9-00c08", issn = "0896-6273", doi = "10.1016/j.neuron.2022.05.003", volume = "110", number = "14", pmcid = "PMC9308721", pages = "2242-2257" } @article{https://authors.library.caltech.edu/records/t9esh-smr07, authors = "Challis, Rosemary C. and Ravindra Kumar, Sripriya and Chen, Xinhong and Goertsen, David and Coughlin, Gerard M. and Hori, Acacia M. and Chuapoco, Miguel R. and Otis, Thomas S. and Miles, Timothy F. and Gradinaru, Viviana", title = "Adeno-Associated Virus Toolkit to Target Diverse Brain Cells", journal = "Annual Review of Neuroscience", publisher = "Annual Reviews", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220525-90416000", id = "https://authors.library.caltech.edu/records/t9esh-smr07", issn = "0147-006X", doi = "10.1146/annurev-neuro-111020-100834", volume = "45", pages = "447-469" } @article{https://authors.library.caltech.edu/records/0h03p-c6230, authors = "Fan, Jiang-peng and Geng, Hui-zhen and Ji, Ya-wei and Jia, Tao and Treweek, Jennifer B. and Li, An-an and Zhou, Chun-yi and Gradinaru, Viviana and Xiao, Cheng", title = "Age-dependent alterations in key components of the nigrostriatal dopaminergic system and distinct motor phenotypes", journal = "Acta Pharmacologica Sinica", publisher = "Nature Publishing Group", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210709-224144084", id = "https://authors.library.caltech.edu/records/0h03p-c6230", issn = "1671-4083", doi = "10.1038/s41401-021-00713-5", volume = "43", number = "4", pmcid = "PMC8975991", pages = "862-875" } @article{https://authors.library.caltech.edu/records/g463t-rp078, authors = "Cui, Lian and Guo, Jeff and Cranfill, Suna L. and Gautam, Mayank and Bhattarai, Janardhan and Olson, William and Beattie, Katherine and Challis, Rosemary C. and Wu, Qinxue and Song, Xue and Raabe, Tobias and Gradinaru, Viviana and Ma, Minghong and Liu, Qin and Luo, Wenqin", title = "Glutamate in primary afferents is required for itch transmission", journal = "Neuron", publisher = "Cell Press", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20220104-157923000", id = "https://authors.library.caltech.edu/records/g463t-rp078", issn = "0896-6273", doi = "10.1016/j.neuron.2021.12.007", volume = "110", number = "5", pmcid = "PMC8898340", pages = "809-823" } @article{https://authors.library.caltech.edu/records/pg7h2-wsy12, authors = "Duan, Yangyang and Ye, Tao and Qu, Zhe and Chen, Yuewen and Miranda, Abigail and Zhou, Xiaopu and Lok, Ka-Chun and Chen, Yu and Fu, Amy K. Y. and Gradinaru, Viviana and Ip, Nancy Y.", title = "Brain-wide Cas9-mediated cleavage of a gene causing familial Alzheimer's disease alleviates amyloid-related pathologies in mice", journal = "Nature Biomedical Engineering", publisher = "Nature Publishing Group", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210728-223917563", id = "https://authors.library.caltech.edu/records/pg7h2-wsy12", issn = "2157-846X", doi = "10.1038/s41551-021-00759-0", volume = "6", number = "2", pages = "168-180" } @article{https://authors.library.caltech.edu/records/ejc84-8zb49, authors = "Goertsen, David and Flytzanis, Nicholas C. and Goeden, Nick and Chuapoco, Miguel R. and Cummins, Alexander and Chen, Yijing and Fan, Yingying and Zhang, Qiangge and Sharma, Jitendra and Duan, Yangyang and Wang, Liping and Feng, Guoping and Chen, Yu and Ip, Nancy Y. and Pickel, James and Gradinaru, Viviana", title = "AAV capsid variants with brain-wide transgene expression and decreased liver targeting after intravenous delivery in mouse and marmoset", journal = "Nature Neuroscience", publisher = "Nature Publishing Group", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20211210-240709000", id = "https://authors.library.caltech.edu/records/ejc84-8zb49", issn = "1097-6256", doi = "10.1038/s41593-021-00969-4", volume = "25", number = "1", pages = "106-115" } @article{https://authors.library.caltech.edu/records/zvjg3-dry41, authors = "Brown, David and Altermatt, Michael and Dobreva, Tatyana and Chen, Sisi and Wang, Alexander and Thomson, Matt and Gradinaru, Viviana", title = "Deep Parallel Characterization of AAV Tropism and AAV-Mediated Transcriptional Changes via Single-Cell RNA Sequencing", journal = "Frontiers in Immunology", publisher = "Frontiers Media", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210629-153450418", id = "https://authors.library.caltech.edu/records/zvjg3-dry41", issn = "1664-3224", doi = "10.3389/fimmu.2021.730825", volume = "12", pmcid = "PMC8574206", pages = "Art. No. 730825" } @article{https://authors.library.caltech.edu/records/h1gp6-1c240, authors = "Davidson, Cristin D. and Gibson, Alana L. and Gu, Tansy and Baxter, Laura L. and Deverman, Benjamin E. and Beadle, Keith and Incao, Arturo A. and Rodriguez-Gil, Jorge L. and Fujiwara, Hideji and Jiang, Xuntian and Chandler, Randy J. and Ory, Daniel S. and Gradinaru, Viviana and Venditti, Charles P. and Pavan, William J.", title = "Improved systemic AAV gene therapy with a neurotrophic capsid in Niemann–Pick disease type C1 mice", journal = "Life Science Alliance", publisher = "Life Science Alliance, LLC", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210930-210049351", id = "https://authors.library.caltech.edu/records/h1gp6-1c240", issn = "2575-1077", doi = "10.26508/lsa.202101040", volume = "4", number = "10", pmcid = "PMC8380657", pages = "Art. No. e202101040" } @article{https://authors.library.caltech.edu/records/6ftpg-4wj22, authors = "Kahan, Anat and Greenbaum, Alon and Jang, Min J. and Robinson, J. Elliott and Cho, Jounhong Ryan and Chen, Xinhong and Kassraian, Pegah and Wagenaar, Daniel A. and Gradinaru, Viviana", title = "Light-guided sectioning for precise in situ localization and tissue interface analysis for brain-implanted optical fibers and GRIN lenses", journal = "Cell Reports", publisher = "Cell Press", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20211008-224633454", id = "https://authors.library.caltech.edu/records/6ftpg-4wj22", issn = "2211-1247", doi = "10.1016/j.celrep.2021.109744", volume = "36", number = "13", pmcid = "PMC8552649", pages = "Art. No. 109744" } @article{https://authors.library.caltech.edu/records/k7txd-cgj35, authors = "Zhu, Meng and Shahbazi, Marta and Martin, Angel and Zhang, Chuanxin and Sozen, Berna and Borsos, Mate and Mandelbaum, Rachel S. and Paulson, Richard J. and Molè, Matteo A. and Esbert, Marga and Titus, Shiny and Scott, Richard T. and Campbell, Alison and Fishel, Simon and Gradinaru, Viviana and Zhao, Han and Wu, Keliang and Chen, Zi-Jiang and Seli, Emre and de los Santos, Maria J. and Zernicka-Goetz, Magdalena", title = "Human embryo polarization requires PLC signaling to mediate trophectoderm specification", journal = "eLife", publisher = "eLife Sciences Publications", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200925-104734056", id = "https://authors.library.caltech.edu/records/k7txd-cgj35", issn = "2050-084X", doi = "10.7554/eLife.65068", volume = "10", pages = "Art. No. e65068" } @article{https://authors.library.caltech.edu/records/gdjer-36e66, authors = "Nagai, Jun and Bellafard, Arash and Qu, Zhen and Yu, Xinzhu and Ollivier, Matthias and Gangwani, Mohitkumar R. and Diaz-Castro, Blanca and Coppola, Giovanni and Schumacher, Sarah M. and Golshani, Peyman and Gradinaru, Viviana and Khakh, Baljit S.", title = "Specific and behaviorally consequential astrocyte G\_q GPCR signaling attenuation in vivo with iβARK", journal = "Neuron", publisher = "Cell Press", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210625-220915439", id = "https://authors.library.caltech.edu/records/gdjer-36e66", issn = "0896-6273", doi = "10.1016/j.neuron.2021.05.023", volume = "109", number = "14", pmcid = "PMC8418870", pages = "2256-2274" } @article{https://authors.library.caltech.edu/records/3mzpv-c6728, authors = "Wu, Wei-Li and Adame, Mark D. and Liou, Chia-Wei and Barlow, Jacob T. and Lai, Tzu-Ting and Sharon, Gil and Schretter, Catherine E. and Needham, Brittany D. and Wang, Madelyn I. and Tang, Weiyi and Ousey, James and Lin, Yuan-Yuan and Yao, Tzu-Hsuan and Abdel-Haq, Reem and Beadle, Keith and Gradinaru, Viviana and Ismagilov, Rustem F. and Mazmanian, Sarkis K.", title = "Microbiota regulate social behaviour via stress response neurons in the brain", journal = "Nature", publisher = "Nature Publishing Group", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210706-202344110", id = "https://authors.library.caltech.edu/records/3mzpv-c6728", issn = "0028-0836", doi = "10.1038/s41586-021-03669-y", volume = "595", number = "7867", pmcid = "PMC8346519", pages = "409-414" } @article{https://authors.library.caltech.edu/records/xbner-74v22, authors = "Smith, Sheena N. and Schubert, Rajib and Simic, Branko and Brücher, Dominik and Schmid, Markus and Kirk, Niels and Freitag, Patrick C. and Gradinaru, Viviana and Pluckthun, Andreas", title = "The SHREAD gene therapy platform for paracrine delivery improves tumor localization and intratumoral effects of a clinical antibody", journal = "Proceedings of the National Academy of Sciences of the United States of America", publisher = "National Academy of Sciences", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210519-141318892", id = "https://authors.library.caltech.edu/records/xbner-74v22", issn = "0027-8424", doi = "10.1073/pnas.2017925118", volume = "118", number = "21", pmcid = "PMC8166199", pages = "Art. 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No. fcab105" } @article{https://authors.library.caltech.edu/records/k5yvf-a4q19, authors = "Graybuck, Lucas T. and Daigle, Tanya L. and Sedeño-Cortés, Adriana E. and Walker, Miranda and Kalmbach, Brian and Lenz, Garreck H. and Morin, Elyse and Nguyen, Thuc Nghi and Garren, Emma and Bendrick, Jacqueline L. and Kim, Tae Kyung and Zhou, Thomas and Mortrud, Marty and Yao, Shenqin and Sieverts, La'Akea and Larsen, Rachael and Gore, Bryan B. and Szelenyi, Eric R. and Trader, Cameron and Balaram, Pooja and van Velthoven, Cindy T. J. and Chiang, Megan and Mich, John K. and Dee, Nick and Goldy, Jeff and Cetin, Ali H. and Smith, Kimberly and Way, Sharon W. and Esposito, Luke and Yao, Zizhen and Gradinaru, Viviana and Sunkin, Susan M. and Lein, Ed and Levi, Boaz P. and Ting, Jonathan T. and Zeng, Hongkui and Tasic, Bosiljka", title = "Enhancer viruses for combinatorial cell-subclass-specific labeling", journal = "Neuron", publisher = "Cell Press", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200421-092814882", id = "https://authors.library.caltech.edu/records/k5yvf-a4q19", issn = "0896-6273", doi = "10.1016/j.neuron.2021.03.011", volume = "109", number = "9", pmcid = "PMC8610077", pages = "1449-1464" } @article{https://authors.library.caltech.edu/records/tf90z-d3h15, authors = "Jang, Min Jee and Coughlin, Gerard M. and Zhang, Yameng and Koulena, Noushin and Schindler, Simone and Cai, Long and Gradinaru, Viviana", title = "Deep Tropism Profiling of Barcoded AAV Capsid and Cargo Pools in Intact Tissue Using High-Throughput Ultrasensitive Sequential FISH", journal = "Molecular Therapy", publisher = "American Society of Gene \& Cell Therapy", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210527-161220137", id = "https://authors.library.caltech.edu/records/tf90z-d3h15", issn = "1525-0016", doi = "10.1016/j.ymthe.2021.04.019", volume = "29", number = "4, S1", pages = "142" } @article{https://authors.library.caltech.edu/records/6cj4j-gpx78, authors = "Chen, Xinhong and Wolfe, Damien A. and Kumar, Sripriya Ravindra and Miles, Timothy F. and Sullivan, Erin E. and Hori, Acacia M. and Ding, Xiaozhe and Gradinaru, Viviana", title = "Endothelial-Tropic AAVs for Genetic Access to Whole-Brain Vasculature in Wild-Type Mouse Strains Following Non-Invasive Systemic Delivery", journal = "Molecular Therapy", publisher = "American Society of Gene \& Cell Therapy", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210528-081450340", id = "https://authors.library.caltech.edu/records/6cj4j-gpx78", issn = "1525-0016", doi = "10.1016/j.ymthe.2021.04.019", volume = "29", number = "4, S1", pages = "25" } @article{https://authors.library.caltech.edu/records/pf45e-w5a27, authors = "Borsos, Máté and Chen, Xinhong and Gradinaru, Viviana", title = "Simultaneous Detection of AAV Genome, Transcript, and Protein Localization in Intact Cells and Tissues at High Resolution", journal = "Molecular Therapy", publisher = "American Society of Gene \& Cell Therapy", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210527-160526973", id = "https://authors.library.caltech.edu/records/pf45e-w5a27", issn = "1525-0016", doi = "10.1016/j.ymthe.2021.04.019", volume = "29", number = "4, S1", pages = "142-143" } @article{https://authors.library.caltech.edu/records/83a8a-23d64, authors = "Hori, Acacia and Grebin, Anastasiya and Robinson, J. Elliott and Chen, Xinhong and Flytzanis, Nick and Goeden, Nick and Chan, Ken and Deverman, Ben and Gradinaru, Viviana", title = "Targeted Gene Therapy with Engineered Systemic AAVs for the Central and Peripheral Nervous Systems Prevents Motor Coordination Phenotypes in a Mouse Model of Friedreich's Ataxia", journal = "Molecular Therapy", publisher = "American Society of Gene \& Cell Therapy", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210528-082042148", id = "https://authors.library.caltech.edu/records/83a8a-23d64", issn = "1525-0016", doi = "10.1016/j.ymthe.2021.04.019", volume = "29", number = "4, S1", pages = "125" } @article{https://authors.library.caltech.edu/records/hfhnb-zj890, authors = "Helseth, Ashley R. and Hernandez-Martinez, Ricardo and Hall, Victoria L. and Oliver, Matthew L. and Turner, Brandon D. and Caffall, Zachary F. and Rittiner, Joseph E. and Shipman, Miranda K. and King, Connor S. and Gradinaru, Viviana and Gerfen, Charles and Costa-Mattioli, Mauro and Calakos, Nicole", title = "Cholinergic neurons constitutively engage the ISR for dopamine modulation and skill learning in mice", journal = "Science", publisher = "American Association for the Advancement of Science", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210428-094505098", id = "https://authors.library.caltech.edu/records/hfhnb-zj890", issn = "0036-8075", doi = "10.1126/science.abe1931", volume = "372", number = "6540", pmcid = "PMC8457366", pages = "Art. No. eabe1931" } @article{https://authors.library.caltech.edu/records/twtz6-z9n14, authors = "Mich, John K. and Graybuck, Lucas T. and Hess, Erik E. and Mahoney, Joseph T. and Kojimo, Yoshiko and Ding, Yi and Somasundaram, Saroja and Miller, Jeremy A. and Kalmbach, Brian E. and Radaelli, Cristina and Gore, Bryan B. and Weed, Natalie and Omstead, Victoria and Bishaw, Yemeserach and Shapovalova, Nadiya V. and Martinez, Refugio A. and Fong, Olivia and Yao, Shenqin and Mortrud, Marty and Chong, Peter and Loftus, Luke and Bertagnolli, Darren and Goldy, Jeff and Casper, Tamara and Dee, Nick and Opitz-Araya, Ximena and Cetin, Ali and Smith, Kimberly A. and Gwinn, Ryder P. and Cobbs, Charles and Ko, Andrew L. and Ojemann, Jeffrey G. and Keene, C. Dirk and Silbergeld, Daniel L. and Sunkin, Susan M. and Gradinaru, Viviana and Horwitz, Gregory D. and Zeng, Hongkui and Tasic, Bosiljka and Lein, Ed S. and Ting, Jonathan T. and Levi, Boaz P.", title = "Functional enhancer elements drive subclass-selective expression from mouse to primate neocortex", journal = "Cell Reports", publisher = "Elsevier", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200421-093728277", id = "https://authors.library.caltech.edu/records/twtz6-z9n14", issn = "2211-1247", doi = "10.1016/j.celrep.2021.108754", volume = "34", number = "13", pages = "Art. No. 108754" } @article{https://authors.library.caltech.edu/records/hk6b4-y9189, authors = "Cho, Jounhong Ryan and Chen, Xinhong and Kahan, Anat and Robinson, J. Elliott and Wagenaar, Daniel A. and Gradinaru, Viviana", title = "Dorsal Raphe Dopamine Neurons Signal Motivational Salience Dependent on Internal State, Expectation, and Behavioral Context", journal = "Journal of Neuroscience", publisher = "Society for Neuroscience", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200728-094010838", id = "https://authors.library.caltech.edu/records/hk6b4-y9189", issn = "0270-6474", doi = "10.1523/JNEUROSCI.2690-20.2021", volume = "41", number = "12", pmcid = "PMC8018733", pages = "2645-2655" } @article{https://authors.library.caltech.edu/records/hjhgm-hc812, authors = "Unger, Elizabeth K. and Keller, Jacob P. and Altermatt, Michael and Liang, Ruqiang and Matsui, Aya and Dong, Chunyang and Hon, Olivia J. and Yao, Zizhen and Sun, Junqing and Banala, Sambashiva and Flanigan, Meghan E. and Jaffe, David A. and Hartanto, Samantha and Carlen, Jane and Mizuno, Grace O. and Borden, Phillip M. and Shivange, Amol V. and Cameron, Lindsay P. and Sinning, Steffen and Underhill, Suzanne M. and Olson, David E. and Amara, Susan G. and Temple Lang, Duncan and Rudnick, Gary and Marvin, Jonathan S. and Lavis, Luke D. and Lester, Henry A. and Alvarez, Veronica A. and Fisher, Andrew J. and Prescher, Jennifer A. and Kash, Thomas L. and Yarov-Yarovoy, Vladimir and Gradinaru, Viviana and Looger, Loren L. and Tian, Lin", title = "Directed Evolution of a Selective and Sensitive Serotonin Sensor via Machine Learning", journal = "Cell", publisher = "Cell Press", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20201217-143607354", id = "https://authors.library.caltech.edu/records/hjhgm-hc812", issn = "0092-8674", doi = "10.1016/j.cell.2020.11.040", volume = "183", number = "7", pmcid = "PMC8025677", pages = "1986-2002" } @article{https://authors.library.caltech.edu/records/0pen5-78s90, authors = "Badimon, Ana and Strasburger, Hayley J. and Ayata, Pinar and Chen, Xinhong and Nair, Aditya and Ikegami, Ako and Hwang, Philip and Chan, Andrew T. and Graves, Steven M. and Uweru, Jospeh O. and Ledderose, Carola and Gunes Kutlu, Munir and Wheeler, Michael A. and Kahan, Anat and Ishikawa, Masago and Wang, Ying-Chih and Loh, Yong-Hwee E. and Jiang, Jean X. and Sumeier, D. James and Robson, Simon C. and Junger, Wolfgang G. and Sebra, Robert and Calipari, Erin S. and Kenny, Paul J. and Eyo, Ukpong B. and Colonna, Marco and Qunitana, Francisco J. and Wake, Hiroaki and Gradinaru, Viviana and Schaefer, Anne", title = "Negative feedback control of neuronal activity by microglia", journal = "Nature", publisher = "Nature Publishing Group", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200817-140210217", id = "https://authors.library.caltech.edu/records/0pen5-78s90", issn = "0028-0836", doi = "10.1038/s41586-020-2777-8", volume = "586", number = "7829", pages = "417-423" } @article{https://authors.library.caltech.edu/records/m1wxm-btm54, authors = "Gradinaru, Viviana", title = "Expanding the brain researcher's toolkit", journal = "Science", publisher = "American Association for the Advancement of Science", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200810-121624161", id = "https://authors.library.caltech.edu/records/m1wxm-btm54", issn = "0036-8075", doi = "10.1126/science.abd2660", volume = "369", number = "6504", pages = "637" } @article{https://authors.library.caltech.edu/records/zrpnd-mj732, authors = "Ravindra Kumar, Sripriya and Miles, Timothy F. and Chen, Xinhong and Brown, David and Dobreva, Tatyana and Huang, Qin and Ding, Xiaozhe and Luo, Yicheng and Einarsson, Petur H. and Greenbaum, Alon and Jang, Min J. and Deverman, Benjamin E. and Gradinaru, Viviana", title = "Multiplexed Cre-dependent selection yields systemic AAVs for targeting distinct brain cell types", journal = "Nature Methods", publisher = "Nature Publishing Group", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200121-141523675", id = "https://authors.library.caltech.edu/records/zrpnd-mj732", issn = "1548-7091", doi = "10.1038/s41592-020-0799-7", volume = "17", number = "5", pmcid = "PMC7219404", pages = "541-550" } @article{https://authors.library.caltech.edu/records/jev5y-8ky19, authors = "Seo, Jai Woong and Ingham, Elizabeth S. and Mahakian, Lisa and Tumbale, Spencer and Wu, Bo and Aghevlian, Sadaf and Shams, Shahin and Baikoghli, Mo and Jain, Poorva and Ding, Xiaozhe and Goeden, Nick and Dobreva, Tatyana and Flytzanis, Nicholas C. and Chavez, Michael and Singhal, Kratika and Leib, Ryan and James, Michelle L. and Segal, David J. and Cheng, R. Holland and Silva, Eduardo A. and Gradinaru, Viviana and Ferrara, Katherine W.", title = "Positron emission tomography imaging of novel AAV capsids maps rapid brain accumulation", journal = "Nature Communications", publisher = "Nature Publishing Group", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200504-132509459", id = "https://authors.library.caltech.edu/records/jev5y-8ky19", issn = "2041-1723", doi = "10.1038/s41467-020-15818-4", volume = "11", pmcid = "PMC7193641", pages = "Art. No. 2102" } @article{https://authors.library.caltech.edu/records/zk45d-25a12, authors = "Brown, David and Altermatt, Michael and Dobreva, Tatyana and Park, Jong H. and Ravindra-Kumar, Sripriya and Chen, Xinhong and Coughlin, Gerard M. and Pool, Allan-Hermann and Thomson, Matt and Gradinaru, Viviana", title = "A Computational and Experimental Platform for Detecting Full Transcriptome Cell Type Tropism of Lowly Expressed Barcoded and Pooled AAV Variants via Single-Cell RNA Sequencing", journal = "Molecular Therapy", publisher = "American Society of Gene \& Cell Therapy", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200604-102237108", id = "https://authors.library.caltech.edu/records/zk45d-25a12", issn = "1525-0016", doi = "10.1016/j.ymthe.2020.04.019", volume = "28", number = "4", pages = "80-81" } @article{https://authors.library.caltech.edu/records/rc28g-k9d42, authors = "Mich, John K. and Gore, Bryan B. and Martinez, Refugio A. and Graybuck, Lucas T. and Mahoney, Joseph T. and Miller, Jeremy A. and Yao, Shenqin and Bertagnolli, Darren and Goldy, Jeff and Hodge, Rebecca D. and Bakken, Trygve E. and Yao, Zizhen and Dee, Nick and Smith, Kimberly A. and Gwinn, Ryder P. and Cobbs, Charles and Ko, Andrew L. and Ojemann, Jeffrey G. and Keene, C. Dirk and Silbergeld, Daniel L. and Gradinaru, Viviana and Zeng, Hongkui and Tasic, Bosiljka and Lein, Ed S. and Ting, Jonathan T. and Levi, Boaz P.", title = "Building a Toolbox of Compact Enhancers for Cell Type-Specific Gene Expression from AAVs in the Primate Brain", journal = "Molecular Therapy", publisher = "American Society of Gene \& Cell Therapy", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200604-134728909", id = "https://authors.library.caltech.edu/records/rc28g-k9d42", issn = "1525-0016", doi = "10.1016/j.ymthe.2020.04.019", volume = "28", number = "4", pages = "70" } @article{https://authors.library.caltech.edu/records/e5ak1-qrv31, authors = "Padia, Umesh and Brown, David and Ding, Xiaozhe and Chen, Xinhong and Kumar, Sripriya R. and Gradinaru, Viviana", title = "Cloud-based Software for NGS Data Management and Analysis for Directed Evolution of Peptide-Based Delivery Vectors", journal = "Molecular Therapy", publisher = "American Society of Gene \& Cell Therapy", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200604-073231089", id = "https://authors.library.caltech.edu/records/e5ak1-qrv31", issn = "1525-0016", doi = "10.1016/j.ymthe.2020.04.019", volume = "28", number = "4", pages = "434-435" } @article{https://authors.library.caltech.edu/records/jtkjw-hfq07, authors = "Ravindra Kumar, Sripriya and Miles, Timothy F. and Chen, Xinhong and Brown, David and Dobreva, Tatyana and Huang, Qin and Ding, Xiaozhe and Luo, Yicheng and Einarsson, Petur and Greenbaum, Alon and Jang, Min Jee and Deverman, Benjamin E. and Gradinaru, Viviana", title = "Evolution and Investigation of Engineered AAV Capsids Exhibiting Enhanced Transduction of the Central Nervous System with or without Murine Strain Specificity", journal = "Molecular Therapy", publisher = "American Society of Gene \& Cell Therapy", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200604-083821035", id = "https://authors.library.caltech.edu/records/jtkjw-hfq07", issn = "1525-0016", doi = "10.1016/j.ymthe.2020.04.019", volume = "28", number = "4", pages = "11-12" } @article{https://authors.library.caltech.edu/records/rrtwx-57q24, authors = "Altermatt, Michael and Brown, David and Dobreva, Tatyana and Jang, Min Jee and Coughlin, Gerard M. and Pool, Allan-Hermann and Thomson, Matt and Gradinaru, Viviana", title = "In-Depth Parallel Profiling of Tissue and Cell-Type Tropism of AAV Variants by Single-Cell RNA Sequencing", journal = "Molecular Therapy", publisher = "American Society of Gene \& Cell Therapy", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200604-075354300", id = "https://authors.library.caltech.edu/records/rrtwx-57q24", issn = "1525-0016", doi = "10.1016/j.ymthe.2020.04.019", volume = "28", number = "4", pages = "399-400" } @article{https://authors.library.caltech.edu/records/n1hwc-rqm20, authors = "Jang, Min Jee and Coughlin, Gerard M. and Zhang, Yameng and Koulena, Noushin and Cai, Long and Gradinaru, Viviana", title = "Method for High-Throughput, In Situ Characterization of AAV Variant Pools in Intact Tissue Using Ultrasensitive Sequential FISH", journal = "Molecular Therapy", publisher = "American Society of Gene \& Cell Therapy", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200604-074008042", id = "https://authors.library.caltech.edu/records/n1hwc-rqm20", issn = "1525-0016", doi = "10.1016/j.ymthe.2020.04.019", volume = "28", number = "4", pages = "78-79" } @article{https://authors.library.caltech.edu/records/63hya-pz836, authors = "Hori, Acacia and Robinson, J. Elliott and Chan, Ken and Flytzanis, Nicholas and Goeden, Nick and Deverman, Ben and Gradinaru, Viviana", title = "Recombinant AAVs Target Custom Frataxin Therapeutic Cassettes to Tissues of Pathophysiologic Relevance in Friedreich's Ataxia", journal = "Molecular Therapy", publisher = "American Society of Gene \& Cell Therapy", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200604-094818518", id = "https://authors.library.caltech.edu/records/63hya-pz836", issn = "1525-0016", doi = "10.1016/j.ymthe.2020.04.019", volume = "28", number = "4", pages = "86-87" } @article{https://authors.library.caltech.edu/records/wbsg5-7hw28, authors = "Ding, Xiaozhe and Gradinaru, Viviana", title = "Structure-Guided Rational Design of Adeno-Associated Viral Capsids with Expanded Sizes", journal = "Molecular Therapy", publisher = "American Society of Gene \& Cell Therapy", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200604-072416648", id = "https://authors.library.caltech.edu/records/wbsg5-7hw28", issn = "1525-0016", doi = "10.1016/j.ymthe.2020.04.019", volume = "28", number = "4", pages = "226-227" } @article{https://authors.library.caltech.edu/records/eyhgz-80z17, authors = "Chen, Xinhong and Ravindra Kumar, Sripriya and Wolfe, Damien and Gradinaru, Viviana", title = "Targeting the Rodent Peripheral Nervous System Efficiently and with Greater Specificity through Intravenous Delivery of AAV Capsids Evolved by Multiplexed-CREATE", journal = "Molecular Therapy", publisher = "American Society of Gene \& Cell Therapy", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200604-073642424", id = "https://authors.library.caltech.edu/records/eyhgz-80z17", issn = "1525-0016", doi = "10.1016/j.ymthe.2020.04.019", volume = "28", number = "4", pages = "252-253" } @article{https://authors.library.caltech.edu/records/6t92d-n0y91, authors = "Goertsen, David and Flytzanis, Nicholas C. and Goeden, Nick and Cummins, Alexander and Pickel, James and Gradinaru, Viviana", title = "Transduction Profiles of Engineered Adeno-Associated Viral Capsids in Mouse and Marmoset", journal = "Molecular Therapy", publisher = "American Society of Gene \& Cell Therapy", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200604-154158513", id = "https://authors.library.caltech.edu/records/6t92d-n0y91", issn = "1525-0016", doi = "10.1016/j.ymthe.2020.04.019", volume = "28", number = "4", pages = "269-270" } @article{https://authors.library.caltech.edu/records/27n9s-n4j49, authors = "Rauch, Jennifer N. and Luna, Gabriel and Guzman, Elmer and Audouard, Morgane and Challis, Collin and Sibih, Youssef E. and Leshuk, Carolina and Hernandez, Israel and Wegmann, Susanne and Hyman, Bradley T. and Gradinaru, Viviana and Kampmann, Martin and Kosik, Kenneth S.", title = "LRP1 is a master regulator of tau uptake and spread", journal = "Nature", publisher = "Nature Publishing Group", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200220-151529138", id = "https://authors.library.caltech.edu/records/27n9s-n4j49", issn = "0028-0836", doi = "10.1038/s41586-020-2156-5", volume = "580", number = "7803", pages = "381-385" } @article{https://authors.library.caltech.edu/records/56ap2-xb768, authors = "Yao, Shenqin and Yuan, Peng and Ouellette, Ben and Zhou, Thomas and Mortrud, Marty and Balaram, Pooja and Chatterjee, Soumya and Wang, Yun and Daigle, Tanya L. and Tasic, Bosiljka and Kuang, Xiuli and Gong, Hui and Luo, Qingming and Zeng, Shaoqun and Curtright, Andrew and Dhaka, Ajay and Kahan, Anat and Gradinaru, Viviana and Chrapkiewicz, Radosław and Schnitzer, Mark and Zeng, Hongkui and Cetin, Ali", title = "RecV recombinase system for in vivo targeted optogenomic modifications of single cells or cell populations", journal = "Nature Methods", publisher = "Nature Publishing Group", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20190220-102621411", id = "https://authors.library.caltech.edu/records/56ap2-xb768", issn = "1548-7091", doi = "10.1038/s41592-020-0774-3", volume = "17", number = "4", pmcid = "PMC7135964", pages = "422-429" } @article{https://authors.library.caltech.edu/records/7r1kt-80y60, authors = "Challis, Collin and Hori, Acacia and Sampson, Timothy R. and Yoo, Bryan B. and Challis, Rosemary C. and Hamilton, Adam M. and Mazmanian, Sarkis K. and Volpicelli-Daley, Laura A. and Gradinaru, Viviana", title = "Gut-seeded α-synuclein fibrils promote gut dysfunction and brain pathology specifically in aged mice", journal = "Nature Neuroscience", publisher = "Nature Publishing Group", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20191209-154036633", id = "https://authors.library.caltech.edu/records/7r1kt-80y60", issn = "1097-6256", doi = "10.1038/s41593-020-0589-7", volume = "23", number = "3", pmcid = "PMC7065967", pages = "327-336" } @article{https://authors.library.caltech.edu/records/2ncza-sht42, authors 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No. e53111" } @article{https://authors.library.caltech.edu/records/4y22j-7j002, authors = "Ueda, Hiroki R. and Ertürk, Ali and Chung, Kwanghun and Gradinaru, Viviana and Chédotal, Alain and Tomancak, Pavel and Keller, Philipp J.", title = "Tissue clearing and its applications in neuroscience", journal = "Nature Reviews. Neuroscience", publisher = "Nature Publishing Group", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200106-082556970", id = "https://authors.library.caltech.edu/records/4y22j-7j002", issn = "1471-003X", doi = "10.1038/s41583-019-0250-1", volume = "21", number = "2", pmcid = "PMC8121164", pages = "61-79" } @article{https://authors.library.caltech.edu/records/de2e1-ej682, authors = "Song, Anying and Dai, Wenting and Jang, Min Jee and Medrano, Leonard and Li, Zhuo and Zhao, Hu and Shao, Mengle and Tan, Jiayi and Li, Aimin and Ning, Tinglu and Miller, Marcia M. and Armstrong, Brian and Huss, Janice M. and Zhu, Yi and Liu, Yong and Gradinaru, Viviana and Wu, Xiwei and Jiang, Lei and Scherer, Philipp E. and Wang, Qiong A.", title = "Low- and high-thermogenic brown adipocyte subpopulations coexist in murine adipose tissue", journal = "Journal of Clinical Investigation", publisher = "American Society for Clinical Investigation", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20191203-132507070", id = "https://authors.library.caltech.edu/records/de2e1-ej682", issn = "0021-9738", doi = "10.1172/jci129167", volume = "130", number = "1", pmcid = "PMC6934193", pages = "247-257" } @article{https://authors.library.caltech.edu/records/8t3hd-cp839, authors = "Patriarchi, Tommaso and Cho, Jounhong Ryan and Merten, Katharina and Marley, Aaron and Broussard, Gerard Joey and Liang, Ruqiang and Williams, John and Nimmerjahn, Axel and von Zastrow, Mark and Gradinaru, Viviana and Tian, Lin", title = "Imaging neuromodulators with high spatiotemporal resolution using genetically encoded indicators", journal = "Nature Protocols", publisher = "Nature Publishing Group", year = "2019", url = "https://resolver.caltech.edu/CaltechAUTHORS:20190801-132221928", id = "https://authors.library.caltech.edu/records/8t3hd-cp839", issn = "1754-2189", doi = "10.1038/s41596-019-0239-2", volume = "14", number = "12", pages = "3471-3505" } @article{https://authors.library.caltech.edu/records/mce30-bne28, authors = "Smith, S. N. and Schubert, R. and Simic, B. and Brücher, D. and Schmid, M. and Gradinaru, V. and Plückthun, A.", title = "Paracrine delivery of therapeutic biologics for cancer", journal = "Human Gene Therapy", publisher = "Mary Ann Liebert", year = "2019", url = "https://resolver.caltech.edu/CaltechAUTHORS:20191216-134424777", id = "https://authors.library.caltech.edu/records/mce30-bne28", issn = "1043-0342", doi = "10.1089/hum.2019.29095.abstracts", volume = "30", number = "11", pages = "A3" } @article{https://authors.library.caltech.edu/records/jh7xg-zzf80, authors = "Bedbrook, Claire N. and Yang, Kevin K. and Robinson, J. Elliott and Mackey, Elisha D. and Gradinaru, Viviana and Arnold, Frances H.", title = "Machine learning-guided channelrhodopsin engineering enables minimally-invasive optogenetics", journal = "Nature Methods", publisher = "Nature Publishing Group", year = "2019", url = "https://resolver.caltech.edu/CaltechAUTHORS:20190304-085432637", id = "https://authors.library.caltech.edu/records/jh7xg-zzf80", issn = "1548-7091", doi = "10.1038/s41592-019-0583-8", volume = "16", number = "11", pmcid = "PMC6858556", pages = "1176-1184" } @article{https://authors.library.caltech.edu/records/h6htr-pne29, authors = "Robinson, J. Elliott and Coughlin, Gerard M. and Hori, Acacia M. and Cho, Jounhong Ryan and Mackey, Elisha D. and Turan, Zeynep and Patriarchi, Tommaso and Tian, Lin and Gradinaru, Viviana", title = "Optical dopamine monitoring with dLight1 reveals mesolimbic phenotypes in a mouse model of neurofibromatosis type 1", journal = "eLife", publisher = "eLife Sciences Publications", year = "2019", url = "https://resolver.caltech.edu/CaltechAUTHORS:20190930-133756080", id = "https://authors.library.caltech.edu/records/h6htr-pne29", issn = "2050-084X", doi = "10.7554/elife.48983", volume = "8", pmcid = "PMC6819083", pages = "Art. No. e48983" } @article{https://authors.library.caltech.edu/records/e3khm-sn905, authors = "Ramirez-Zamora, Adolfo and Gradinaru, Viviana", title = "Proceedings of the Sixth Deep Brain Stimulation Think Tank Modulation of Brain Networks and Application of Advanced Neuroimaging, Neurophysiology, and Optogenetics", journal = "Frontiers in Neuroscience", publisher = "Frontiers", year = "2019", url = "https://resolver.caltech.edu/CaltechAUTHORS:20190926-135813898", id = "https://authors.library.caltech.edu/records/e3khm-sn905", issn = "1662-453X", doi = "10.3389/fnins.2019.00936", volume = "13", pmcid = "PMC6751331", pages = "Art. 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No. 102" } @article{https://authors.library.caltech.edu/records/4wh9a-76m48, authors = "Goeden, Nick and Flytzanis, Nicholas and Gradinaru, Viviana", title = "Engineered AAVs for Enhanced Transduction of Submucosal Cells within the Lung Following Intravenous Delivery", journal = "Molecular Therapy", publisher = "American Society of Gene \& Cell Therapy", year = "2019", url = "https://resolver.caltech.edu/CaltechAUTHORS:20190502-130505856", id = "https://authors.library.caltech.edu/records/4wh9a-76m48", issn = "1525-0016", doi = "10.1016/j.ymthe.2019.04.004", volume = "27", number = "4", pages = "Art. No. 101" } @article{https://authors.library.caltech.edu/records/ebpm3-mcm94, authors = "Ravindra Kumar, Sripriya and Chen, Xinhong and Deverman, Benjamin E. and Brown, David and Dobreva, Tatyana and Huang, Qin and Ding, Xiaozhe and Luo, Yicheng and Einarsson, Petur H. and Goeden, Nick and Flytzanis, Nicholas and Greenbaum, Alon and Gradinaru, Viviana", title = "Multiplexed-CREATE Selection Yields AAV Vectors Targeting Different Cell Types of the Central Nervous System Following Systemic Delivery", journal = "Molecular Therapy", publisher = "American Society of Gene \& Cell Therapy", year = "2019", url = "https://resolver.caltech.edu/CaltechAUTHORS:20190503-152305499", id = "https://authors.library.caltech.edu/records/ebpm3-mcm94", issn = "1525-0016", doi = "10.1016/j.ymthe.2019.04.004", volume = "27", number = "4", pages = "Art. 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No. eaat4422" } @article{https://authors.library.caltech.edu/records/xgk8s-ec475, authors = "Zelikowsky, Moriel and Hui, May and Karigo, Tomomi and Choe, Andrea and Yang, Bin and Blanco, Mario R. and Beadle, Keith and Gradinaru, Viviana and Deverman, Benjamin E. and Anderson, David J.", title = "The Neuropeptide Tac2 Controls a Distributed Brain State Induced by Chronic Social Isolation Stress", journal = "Cell", publisher = "Cell Press", year = "2018", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180518-105323206", id = "https://authors.library.caltech.edu/records/xgk8s-ec475", issn = "0092-8674", doi = "10.1016/j.cell.2018.03.037", volume = "173", number = "5", pmcid = "PMC5967263", pages = "1265-1279" } @article{https://authors.library.caltech.edu/records/eswzw-tcp82, authors = "Ravindra Kumar, Sripriya and Chan, Ken and Jang, Min J. and Huang, Qin and Brown, David and Dobreva, Tatyana and Kim, Hyun M. and Luo, Yicheng and Hurt, Robert C. and Chen, Xinhong and Deverman, Benjamin E. and Gradinaru, Viviana", title = "Developing AAV Vectors for More Efficient and Selective Gene Expression in Specific Cell Types of the Nervous System Following Systemic Delivery", journal = "Molecular Therapy", publisher = "American Society of Gene \& Cell Therapy", year = "2018", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180706-160530988", id = "https://authors.library.caltech.edu/records/eswzw-tcp82", issn = "1525-0016", doi = "10.1016/j.ymthe.2018.05.001", volume = "26", number = "5", pages = "321" } @article{https://authors.library.caltech.edu/records/vhrr1-zfn16, authors = "Flytzanis, Nicholas and Goeden, Nicholas and Cho, Jounhong Ryan and Kahan, Anat and Luongo, Francisco and Tsao, Doris Y. and Deverman, Benjamin E. and Gradinaru, Viviana", title = "Engineering Cell Type Specific Delivery Vectors for Noninvasive Modulation of Brain Circuits and Behaviors", journal = "Molecular Therapy", publisher = "American Society of Gene \& Cell Therapy", year = "2018", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180706-151207096", id = "https://authors.library.caltech.edu/records/vhrr1-zfn16", issn = "1525-0016", doi = "10.1016/j.ymthe.2018.05.001", volume = "26", number = "5", pages = "304" } @article{https://authors.library.caltech.edu/records/dpmpe-csf66, authors = "Gu, Tansy and Davidson, Cristin and Gibson, Alana and Chandler, Randy and Beadle, Keith and Deverman, Ben and Ory, Daniel S. and Gradinaru, Viviana and Pavan, William J. and Venditti, Charles P.", title = "Enhanced Efficacy of Gene Therapy Treatment for Niemann-Pick C1 Disease Using a Novel Serotype, AAV-PHP.B", journal = "Molecular Therapy", publisher = "American Society of Gene \& Cell Therapy", year = "2018", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180706-154255761", id = "https://authors.library.caltech.edu/records/dpmpe-csf66", issn = "1525-0016", doi = "10.1016/j.ymthe.2018.05.001", volume = "26", number = "5", pages = "404" } @article{https://authors.library.caltech.edu/records/1849v-gb697, authors = "Gradinaru, Viviana and Treweek, Jennifer and Overton, Kristin and Deisseroth, Karl", title = "Hydrogel-Tissue Chemistry: Principles and Applications", journal = "Annual Review of Biophysics", publisher = "Annual Reviews", year = "2018", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180529-083813817", id = "https://authors.library.caltech.edu/records/1849v-gb697", issn = "1936-122X", doi = "10.1146/annurev-biophys-070317-032905", volume = "47", pmcid = "PMC6359929", pages = "355-376" } @article{https://authors.library.caltech.edu/records/j25jc-5t646, authors = "Robinson, J. Elliott and Gradinaru, Viviana", title = "Dopaminergic dysfunction in neurodevelopmental disorders: recent advances and synergistic technologies to aid basic research", journal = "Current Opinion in Neurobiology", publisher = "Elsevier", year = "2018", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170918-075519928", id = "https://authors.library.caltech.edu/records/j25jc-5t646", issn = "0959-4388", doi = "10.1016/j.conb.2017.08.003", volume = "48", pmcid = "PMC5825239", pages = "17-29" } @article{https://authors.library.caltech.edu/records/gvqes-kwv35, authors = "Davidson, Cristin and Gibson, Alana and Gu, Tansy and Chandler, Randy and Deverman, Benjamin and Gradinaru, Viviana and Venditti, Charles and Pavan, William", title = "Gene therapy for the treatment of Niemann-Pick disease type C1: Comparison of AAV9 to a novel serotype, AAV-PHP.B", journal = "Molecular Genetics and Metabolism", publisher = "Elsevier", year = "2018", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180301-095437009", id = "https://authors.library.caltech.edu/records/gvqes-kwv35", issn = "1096-7192", doi = "10.1016/j.ymgme.2017.12.075", volume = "123", number = "2", pages = "S36-S37" } @article{https://authors.library.caltech.edu/records/cn3ba-htx34, authors = "Greenbaum, Alon and Chan, Ken and Boyce, Rogely and Salimi-Moosavi, Hossein and McBride, Helen J. and Gradinaru, Viviana", title = "Bone CLARITY reveals that anti-sclerostin antibody penetrates the lacunar canalicular system in mice under physiological loading conditions", journal = "Journal of Bone and Mineral Research", publisher = "Wiley", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180108-144650592", id = "https://authors.library.caltech.edu/records/cn3ba-htx34", issn = "0884-0431", doi = "10.1002/jbmr.3363", volume = "32", number = "S1", pages = "S293" } @article{https://authors.library.caltech.edu/records/p04pt-mv098, authors = "Ruan, Haowen and Brake, Joshua and Robinson, J. Elliott and Liu, Yan and Jang, Mooseok and Xiao, Cheng and Zhou, Chunyi and Gradinaru, Viviana and Yang, Changhuei", title = "Deep tissue optical focusing and optogenetic modulation with time-reversed ultrasonically encoded light", journal = "Science Advances", publisher = "American Association for the Advancement of Science", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20171107-132336726", id = "https://authors.library.caltech.edu/records/p04pt-mv098", issn = "2375-2548", doi = "10.1126/sciadv.aao5520", volume = "3", number = "12", pmcid = "PMC5722648", pages = "Art. No. eaao5520" } @article{https://authors.library.caltech.edu/records/6tav9-rp997, authors = "Gradinaru, Viviana", title = "Overriding sleep", journal = "Science", publisher = "American Association for the Advancement of Science", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20171127-142458372", id = "https://authors.library.caltech.edu/records/6tav9-rp997", issn = "0036-8075", doi = "10.1126/science.aap9535", volume = "358", number = "6362", pages = "457-457" } @article{https://authors.library.caltech.edu/records/ptv4z-1sb38, authors = "Bedbrook, Claire N. and Yang, Kevin K. and Rice, Austin J. and Gradinaru, Viviana and Arnold, Frances H.", title = "Machine learning to design integral membrane channelrhodopsins for efficient eukaryotic expression and plasma membrane localization", journal = "PLOS Computational Biology", publisher = "Public Library of Science", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20171030-140148566", id = "https://authors.library.caltech.edu/records/ptv4z-1sb38", issn = "1553-7358", doi = "10.1371/journal.pcbi.1005786", volume = "13", number = "10", pmcid = "PMC5695628", pages = "Art. No. e1005786" } @article{https://authors.library.caltech.edu/records/psp7j-nmv35, authors = "Nath, Ravi D. and Bedbrook, Claire N. and Abrams, Michael J. and Basinger, Ty and Bois, Justin S. and Prober, David A. and Sternberg, Paul W. and Gradinaru, Viviana and Goentoro, Lea", title = "The Jellyfish Cassiopea Exhibits a Sleep-like State", journal = "Current Biology", publisher = "Cell Press", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170921-075913502", id = "https://authors.library.caltech.edu/records/psp7j-nmv35", issn = "0960-9822", doi = "10.1016/j.cub.2017.08.014", volume = "27", number = "19", pmcid = "PMC5653286", pages = "2984-2990" } @article{https://authors.library.caltech.edu/records/nr034-pht93, authors = "Greenbaum, Alon and Jang, Min J. and Challis, Collin and Gradinaru, Viviana", title = "Q\&A: How can advances in tissue clearing and optogenetics contribute to our understanding of normal and diseased biology?", journal = "BMC Biology", publisher = "BioMed Central", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170926-130537624", id = "https://authors.library.caltech.edu/records/nr034-pht93", issn = "1741-7007", doi = "10.1186/s12915-017-0421-3", volume = "15", pmcid = "PMC5613628", pages = "Art. No. 87" } @article{https://authors.library.caltech.edu/records/kehhk-szz26, authors = "Chan, Ken Y. and Jang, Min J. and Yoo, Bryan B. and Greenbaum, Alon and Ravi, Namita and Wu, Wei-Li and Sánchez-Guardado, Luis and Lois, Carlos and Mazmanian, Sarkis K. and Deverman, Benjamin E. and Gradinaru, Viviana", title = "Engineered AAVs for efficient noninvasive gene delivery to the central and peripheral nervous systems", journal = "Nature Neuroscience", publisher = "Springer Nature", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170626-152125765", id = "https://authors.library.caltech.edu/records/kehhk-szz26", issn = "1097-6256", doi = "10.1038/nn.4593", volume = "20", number = "8", pmcid = "PMC5529245", pages = "1172-1179" } @article{https://authors.library.caltech.edu/records/9tv57-7fw75, authors = "Cho, Jounhong Ryan and Treweek, Jennifer B. and Robinson, J. Elliott and Xiao, Cheng and Bremner, Lindsay R. and Greenbaum, Alon and Gradinaru, Viviana", title = "Dorsal Raphe Dopamine Neurons Modulate Arousal and Promote Wakefulness by Salient Stimuli", journal = "Neuron", publisher = "Elsevier", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170609-094413808", id = "https://authors.library.caltech.edu/records/9tv57-7fw75", issn = "0896-6273", doi = "10.1016/j.neuron.2017.05.020", volume = "94", number = "6", pages = "1205-1219" } @article{https://authors.library.caltech.edu/records/m8ah5-thb30, authors = "Allen, William E. and Kauvar, Isaac V. and Chen, Michael Z. and Richman, Ethan B. and Yang, Samuel J. and Chan, Ken and Gradinaru, Viviana and Deverman, Benjamin E. and Luo, Liqun and Deisseroth, Karl", title = "Global Representations of Goal-Directed Behavior in Distinct Cell Types of Mouse Neocortex", journal = "Neuron", publisher = "Cell Press", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170522-103736207", id = "https://authors.library.caltech.edu/records/m8ah5-thb30", issn = "0896-6273", doi = "10.1016/j.neuron.2017.04.017", volume = "94", number = "4", pmcid = "PMC5723385", pages = "891-907" } @article{https://authors.library.caltech.edu/records/k9dq3-nnt81, authors = "Gibson, Alana L. and Davidson, Cristin D. and Chandler, Randy J. and Deverman, Benjamin E. and Incao, Arturo A. and Hubbard, Brandon T. and Gradinaru, Viviana and Pavan, William J. and Venditti, Charles P.", title = "Adeno-Associated Viral Gene Therapy Using PHP.B:NPC1 Ameliorates Disease Phenotype in Mouse Model of Niemann-Pick C1 Disease", journal = "Molecular Therapy", publisher = "American Society of Gene \& Cell Therapy", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170601-080728015", id = "https://authors.library.caltech.edu/records/k9dq3-nnt81", issn = "1525-0016", doi = "10.1016/j.ymthe.2017.04.025", volume = "25", number = "5", pages = "Art. No. 225" } @article{https://authors.library.caltech.edu/records/j7rz1-8mn46, authors = "Greenbaum, Alon and Chan, Ken Y. and Dobreva, Tatyana and Brown, David and Balani, Deepak H. and Boyce, Rogely and Kronenberg, Henry M. and McBride, Helen J. and Gradinaru, Viviana", title = "Bone CLARITY: Clearing, imaging, and computational analysis of osteoprogenitors within intact bone marrow", journal = "Science Translational Medicine", publisher = "American Association for the Advancement of Science", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20161221-135116035", id = "https://authors.library.caltech.edu/records/j7rz1-8mn46", issn = "1946-6234", doi = "10.1126/scitranslmed.aah6518", volume = "9", number = "387", pages = "Art. No. eaah6518" } @article{https://authors.library.caltech.edu/records/239ws-b2z58, authors = "Bedbrook, Claire N. and Rice, Austin J. and Yang, Kevin K. and Ding, Xiaozhe and Chen, Siyuan and LeProust, Emily M. and Gradinaru, Viviana and Arnold, Frances H.", title = "Structure-guided SCHEMA recombination generates diverse chimeric channelrhodopsins", journal = "Proceedings of the National Academy of Sciences of the United States of America", publisher = "National Academy of Sciences", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170310-130542741", id = "https://authors.library.caltech.edu/records/239ws-b2z58", issn = "0027-8424", doi = "10.1073/pnas.1700269114", volume = "114", number = "13", pmcid = "PMC5380088", pages = "E2624-E2633" } @article{https://authors.library.caltech.edu/records/eyt49-dzw75, authors = "Herwig, Lukas and Rice, Austin J. and Bedbrook, Claire N. and Zhang, Ruijie K. and Lignell, Antti and Cahn, Jackson K. B. and Renata, Hans and Dodani, Sheel C. and Cho, Inha and Cai, Long and Gradinaru, Viviana and Arnold, Frances H.", title = "Directed Evolution of a Bright Near-Infrared Fluorescent Rhodopsin Using a Synthetic Chromophore", journal = "Cell Chemical Biology", publisher = "Cell Press", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20170307-082231020", id = "https://authors.library.caltech.edu/records/eyt49-dzw75", issn = "2451-9456", doi = "10.1016/j.chembiol.2017.02.008", volume = "24", number = "3", pmcid = "PMC5357175", pages = "415-425" } @article{https://authors.library.caltech.edu/records/xwekr-he073, authors = "Mazmanian, Sarkis K. and Sampson, Timothy R. and Debelius, Justine W. and Thron, Taren and Janssen, Stefan and Shastri, Gauri G. and Ilhan, Esra and Challis, Collin and Schretter, Catherine E. and Rocha, Sandra and Gradinaru, Viviana and Chesselet, Marie-Francoise and Keshavarzian, Ali and Shannon, Kathleen M. and Krajmalnik-Brown, Rosa and Wittung-Stafshede, Pernilla and Knight, Rob", title = "Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson's Disease", journal = "Cell", publisher = "Cell Press", year = "2016", url = "https://resolver.caltech.edu/CaltechAUTHORS:20161115-114016210", id = "https://authors.library.caltech.edu/records/xwekr-he073", issn = "0092-8674", doi = "10.1016/j.cell.2016.11.018", volume = "167", number = "6", pmcid = "PMC5718049", pages = "1469-1480" } @article{https://authors.library.caltech.edu/records/p1jf2-4kh88, authors = "Fairhall, Adrienne and Svoboda, Karel and Nobre, Anna C. and Gradinaru, Viviana and Nusser, Zoltan and Ghosh, Anirvan and Tsien, Richard", title = "Global Collaboration, Learning from Other Fields", journal = "Neuron", publisher = "Elsevier", year = "2016", url = "https://resolver.caltech.edu/CaltechAUTHORS:20161128-093036959", id = "https://authors.library.caltech.edu/records/p1jf2-4kh88", issn = "0896-6273", doi = "10.1016/j.neuron.2016.10.040", volume = "92", number = "3", pages = "561-563" } @article{https://authors.library.caltech.edu/records/agxyk-a4992, authors = "Pan, Min and Reid, Michael A. and Lowman, Xazmin H. and Kulkarni, Rajan P. and Tran, Thai Q. and Liu, Xiaojing and Yang, Ying and Hernandez-Davies, Jenny E. and Rosales, Kimberly K. and Li, Haiqing and Hugo, Willy and Song, Chunying and Xu, Xiangdong and Schones, Dustin E. and Ann, David K. and Gradinaru, Viviana and Lo, Roger S. and Locasale, Jason W. and Kong, Mei", title = "Regional glutamine deficiency in tumours promotes dedifferentiation through inhibition of histone demethylation", journal = "Nature Cell Biology", publisher = "Nature Publishing Group", year = "2016", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160920-092113773", id = "https://authors.library.caltech.edu/records/agxyk-a4992", issn = "1465-7392", doi = "10.1038/ncb3410", volume = "18", number = "10", pmcid = "PMC5536113", pages = "1090-1101" } @article{https://authors.library.caltech.edu/records/e2n6h-2v807, authors = "DePas, William H. and Starwalt-Lee, Ruth and Van Sambeek, Lindsey and Ravindra Kumar, Sripriya and Gradinaru, Viviana and Newman, Dianne K.", title = "Exposing the Three-Dimensional Biogeography and Metabolic States of Pathogens in Cystic Fibrosis Sputum via Hydrogel Embedding, Clearing, and rRNA Labeling", journal = "mBio", publisher = "American Society for Microbiology", year = "2016", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160927-144217261", id = "https://authors.library.caltech.edu/records/e2n6h-2v807", issn = "2150-7511", doi = "10.1128/mBio.00796-16", volume = "7", number = "5", pmcid = "PMC5040109", pages = "e00796-16" } @article{https://authors.library.caltech.edu/records/npxan-57878, authors = "Shah, Sheel and Lubeck, Eric and Schwarzkopf, Maayan and He, Ting-Fang and Greenbaum, Alon and Sohn, Chang Ho and Lignell, Antti and Choi, Harry M. T. and Gradinaru, Viviana and Pierce, Niles A. and Cai, Long", title = "Single-molecule RNA detection at depth via hybridization chain reaction and tissue hydrogel embedding and clearing", journal = "Development", publisher = "Company of Biologists", year = "2016", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160628-085406782", id = "https://authors.library.caltech.edu/records/npxan-57878", issn = "0950-1991", doi = "10.1242/dev.138560", volume = "143", number = "15", pmcid = "PMC5004914", pages = "2862-2867" } @article{https://authors.library.caltech.edu/records/wcraa-mcj63, authors = "Treweek, Jennifer Brooke and Gradinaru, Viviana", title = "Extracting structural and functional features of widely distributed biological circuits with single cell resolution via tissue clearing and delivery vectors", journal = "Current Opinion in Biotechnology", publisher = "Elsevier", year = "2016", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160712-101339180", id = "https://authors.library.caltech.edu/records/wcraa-mcj63", issn = "0958-1669", doi = "10.1016/j.copbio.2016.03.012", volume = "40", pmcid = "PMC4975678", pages = "193-207" } @article{https://authors.library.caltech.edu/records/qk83w-f4y03, authors = "Deverman, Benjamin E. and Pravdo, Piers L. and Simpson, Bryan P. and Ravindra Kumar, Sripriya and Luo, Yicheng and Chan, Ken Y. and Banerjee, Abhik and Wu, Wei-Li and Yang, Bin and Huber, Nina and Pasca, Sergiu P. and Gradinaru, Viviana", title = "Using Cre-Dependent In Vivo Selection to Identify AAV Variants That Enable Efficient and Widespread Gene Transfer to the Adult Central Nervous System", journal = "Molecular Therapy", publisher = "American Society of Gene \& Cell Therapy", year = "2016", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160527-092723542", id = "https://authors.library.caltech.edu/records/qk83w-f4y03", issn = "1525-0016", doi = "10.1016/S1525-0016(16)33061-1", volume = "24", number = "S1", pages = "S99" } @article{https://authors.library.caltech.edu/records/px9eg-37y87, authors = "Xiao, Cheng and Cho, Jounhong Ryan and Zhou, Chunyi and Treweek, Jennifer B. and Chan, Ken and McKinney, Sheri L. and Yang, Bin and Gradinaru, Viviana", title = "Cholinergic Mesopontine Signals Govern Locomotion and Reward through Dissociable Midbrain Pathways", journal = "Neuron", publisher = "Cell Press", year = "2016", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160420-090626768", id = "https://authors.library.caltech.edu/records/px9eg-37y87", issn = "0896-6273", doi = "10.1016/j.neuron.2016.03.028", volume = "90", number = "2", pmcid = "PMC4840478", pages = "333-347" } @article{https://authors.library.caltech.edu/records/j19ev-9mb91, authors = "Rice, Austin J. and Bedbrook, Claire N. and Yang, Kevin K. and Gradinaru, Viviana and Arnold, Frances H.", title = "Rhodopsin Engineering through Structure-Guided Recombination", journal = "Biophysical Journal", publisher = "Biophysical Society", year = "2016", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160603-153016574", id = "https://authors.library.caltech.edu/records/j19ev-9mb91", issn = "0006-3495", doi = "10.1016/j.bpj.2015.11.947", volume = "110", number = "3", pages = "170A" } @article{https://authors.library.caltech.edu/records/ezhsc-jnr62, authors = "Gradinaru, Viviana", title = "Tools for Anatomical and Functional Analysis of Widely Distributed Brain Networks", journal = "Biophysical Journal", publisher = "Biophysical Society", year = "2016", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160606-133730058", id = "https://authors.library.caltech.edu/records/ezhsc-jnr62", issn = "0006-3495", doi = "10.1016/j.bpj.2015.11.1965", volume = "110", number = "3", pages = "364A-365A" } @article{https://authors.library.caltech.edu/records/sgthf-gne05, authors = "Deverman, Benjamin E. and Pravdo, Piers L. and Simpson, Bryan P. and Ravindra Kumar, Sripriya and Chan, Ken Y. and Banerjee, Abhik and Wu, Wei-Li and Yang, Bin and Huber, Nina and Pasca, Sergiu P. and Gradinaru, Viviana", title = "Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain", journal = "Nature Biotechnology", publisher = "Nature Publishing Group", year = "2016", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160201-131537838", id = "https://authors.library.caltech.edu/records/sgthf-gne05", issn = "1087-0156", doi = "10.1038/nbt.3440", volume = "34", number = "2", pmcid = "PMC5088052", pages = "204-209" } @article{https://authors.library.caltech.edu/records/vj1b1-mdj56, authors = "Gradinaru, Viviana and Flytzanis, Nicholas C.", title = "Fluorescent boost for voltage sensors", journal = "Nature", publisher = "Nature Publishing Group", year = "2016", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160202-092152118", id = "https://authors.library.caltech.edu/records/vj1b1-mdj56", issn = "0028-0836", doi = "10.1038/529469a", volume = "529", number = "7587", pages = "469-470" } @article{https://authors.library.caltech.edu/records/yx9xd-rk111, authors = "Skennerton, Connor T. and Ward, Lewis M. and Michel, Alice and Metcalfe, Kyle and Valiente, Chanel and Mullin, Sean and Chan, Ken Y. and Gradinaru, Viviana and Orphan, Victoria J.", title = "Genomic Reconstruction of an Uncultured Hydrothermal Vent Gammaproteobacterial Methanotroph (Family Methylothermaceae) Indicates Multiple Adaptations to Oxygen Limitation", journal = "Frontiers in Microbiology", publisher = "Frontiers Research Foundation", year = "2015", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160108-103050704", id = "https://authors.library.caltech.edu/records/yx9xd-rk111", issn = "1664-302X", doi = "10.3389/fmicb.2015.01425", volume = "6", pmcid = "PMC4688376", pages = "Art. No. 1425" } @article{https://authors.library.caltech.edu/records/e4qmn-syf18, authors = "Treweek, Jennifer B. and Chan, Ken Y. and Flytzanis, Nicholas C. and Yang, Bin and Deverman, Benjamin E. and Greenbaum, Alon and Lignell, Antti and Xiao, Cheng and Cai, Long and Ladinsky, Mark S. and Bjorkman, Pamela J. and Fowlkes, Charless C. and Gradinaru, Viviana", title = "Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high-resolution intact circuit mapping and phenotyping", journal = "Nature Protocols", publisher = "Nature Publishing Group", year = "2015", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150914-123933415", id = "https://authors.library.caltech.edu/records/e4qmn-syf18", issn = "1754-2189", doi = "10.1038/nprot.2015.122", volume = "10", number = "11", pmcid = "PMC4917295", pages = "1860-1896" } @article{https://authors.library.caltech.edu/records/746rc-19032, authors = "Bedbrook, Claire N. and Kato, Mihoko and Ravindra Kumar, Sripriya and Lakshmanan, Anupama and Nath, Ravi D. and Sun, Fei and Sternberg, Paul W. and Arnold, Frances H. and Gradinaru, Viviana", title = "Genetically Encoded Spy Peptide Fusion System to Detect Plasma Membrane-Localized Proteins In Vivo", journal = "Chemistry and Biology", publisher = "Cell Press", year = "2015", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150728-090618874", id = "https://authors.library.caltech.edu/records/746rc-19032", issn = "1074-5521", doi = "10.1016/j.chembiol.2015.06.020", volume = "22", number = "8", pmcid = "PMC4546540", pages = "1108-1121" } @article{https://authors.library.caltech.edu/records/70kmm-8py90, authors = "Flytzanis, Nicholas C. and Bedbrook, Claire N. and Chiu, Hui and Engqvist, Martin K. M. and Xiao, Cheng and Chan, Ken Y. and Sternberg, Paul W. and Arnold, Frances H. and Gradinaru, Viviana", title = "Archaerhodopsin variants with enhanced voltage-sensitive fluorescence in mammalian and Caenorhabditis elegans neurons", journal = "Nature Communications", publisher = "Nature Publishing Group", year = "2014", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140730-113211664", id = "https://authors.library.caltech.edu/records/70kmm-8py90", issn = "2041-1723", doi = "10.1038/ncomms5894", volume = "5", number = "9", pmcid = "PMC4166526", pages = "Art. No. 4894" } @article{https://authors.library.caltech.edu/records/7hzm0-wtx83, authors = "McIsaac, R. Scott and Engqvist, Martin K. M. and Wannier, Timothy and Rosenthal, Adam Z. and Herwig, Lukas and Flytzanis, Nicholas C. and Imasheva, Eleonora S. and Lanyi, Janos K. and Balashov, Sergei P. and Gradinaru, Viviana and Arnold, Frances H.", title = "Directed evolution of a far-red fluorescent rhodopsin", journal = "Proceedings of the National Academy of Sciences of the United States of America", publisher = "National Academy of Sciences", year = "2014", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140825-213535516", id = "https://authors.library.caltech.edu/records/7hzm0-wtx83", issn = "0027-8424", doi = "10.1073/pnas.1413987111", volume = "111", number = "36", pmcid = "PMC4246972", pages = "13034-13039" } @article{https://authors.library.caltech.edu/records/k57mg-mbq97, authors = "Yang, Bin and Treweek, Jennifer B. and Kulkarni, Rajan P. and Deverman, Benjamin E. and Chen, Chun-Kan and Lubeck, Eric and Shah, Sheel and Cai, Long and Gradinaru, Viviana", title = "Single-Cell Phenotyping within Transparent Intact Tissue through Whole-Body Clearing", journal = "Cell", publisher = "Elsevier", year = "2014", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140801-121634734", id = "https://authors.library.caltech.edu/records/k57mg-mbq97", issn = "0092-8674", doi = "10.1016/j.cell.2014.07.017", volume = "158", number = "4", pmcid = "PMC4153367", pages = "945-958" } @article{https://authors.library.caltech.edu/records/f6stc-5k993, authors = "Birmingham, Karen and Gradinaru, Viviana and Anikeeva, Polina and Grill, Warren M. and Pikov, Victor and McLaughlin, Bryan and Pasricha, Pankaj and Weber, Douglas and Ludwig, Kip and Famm, Kristoffer", title = "Bioelectronic medicines: a research roadmap", journal = "Nature Reviews Drug Discovery", publisher = "Nature Publishing Group", year = "2014", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140714-121054059", id = "https://authors.library.caltech.edu/records/f6stc-5k993", issn = "1474-1776", doi = "10.1038/nrd4351", volume = "13", number = "6", pages = "399-400" } @article{https://authors.library.caltech.edu/records/mqyw4-6hn71, authors = "Chung, Kwanghun and Wallace, Jenelle and Kim, Sung-Yon and Kalyanasundaram, Sandhiya and Andalman, Aaron S. and Davidson, Thomas J. and Mirzabekov, Julie J. and Zalocusky, Kelly A. and Mattis, Joanna and Denisin, Aleksandra K. and Pak, Sally and Bernstein, Hannah and Ramakrishnan, Charu and Grosenick, Logan and Gradinaru, Viviana and Deisseroth, Karl", title = "Structural and molecular interrogation of intact biological systems", journal = "Nature", publisher = "Nature Publishing Group", year = "2013", url = "https://resolver.caltech.edu/CaltechAUTHORS:20130513-151857819", id = "https://authors.library.caltech.edu/records/mqyw4-6hn71", issn = "0028-0836", doi = "10.1038/nature12107", volume = "497", number = "7449", pmcid = "PMC4092167", pages = "332-337" } @article{https://authors.library.caltech.edu/records/a043p-7sh38, authors = "Sukhotinsky, Inna and Chan, Alexander M. and Ahmed, Omar J. and Rao, Vikram R. and Gradinaru, Viviana and Ramakrishnan, Charu and Deisseroth, Karl and Majewska, Ania K. and Cash, Sydney S.", title = "Optogenetic Delay of Status Epilepticus Onset in an In Vivo Rodent Epilepsy Model", journal = "PLoS ONE", publisher = "Public Library of Science", year = "2013", url = "https://resolver.caltech.edu/CaltechAUTHORS:20130513-151856843", id = "https://authors.library.caltech.edu/records/a043p-7sh38", issn = "1932-6203", doi = "10.1371/journal.pone.0062013", volume = "8", number = "4", pmcid = "PMC3634849", pages = "e62013" } @article{https://authors.library.caltech.edu/records/8hdv1-v7263, authors = "Mattis, Joanna and Tye, Kay M. and Ferenczi, Emily A. and Ramakrishnan, Charu and O'Shea, Daniel J. and Prakash, Rohit and Gunaydin, Lisa A. and Hyun, Minsuk and Fenno, Lief E. and Gradinaru, Viviana and Yizhar, Ofer and Deisseroth, Karl", title = "Principles for applying optogenetic tools derived from direct comparative analysis of microbial 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"1562-1568" } @article{https://authors.library.caltech.edu/records/vcbsm-yey23, authors = "Goshen, Inbal and Brodsky, Matthew and Prakash, Rohit and Wallace, Jenelle and Gradinaru, Viviana and Ramakrishnan, Charu and Deisseroth, Karl", title = "Dynamics of Retrieval Strategies for Remote Memories", journal = "Cell", publisher = "Elsevier", year = "2011", url = "https://resolver.caltech.edu/CaltechAUTHORS:20121206-085452439", id = "https://authors.library.caltech.edu/records/vcbsm-yey23", issn = "0092-8674", doi = "10.1016/j.cell.2011.09.033", volume = "147", number = "3", pages = "678-689" } @article{https://authors.library.caltech.edu/records/hx8md-xvw19, authors = "Tye, Kay M. and Prakash, Rohit and Kim, Sung-Yon and Fenno, Lief E. and Grosenick, Logan and Zarabi, Hosniya and Thompson, Kimberly R. and Gradinaru, Viviana and Ramakrishnan, Charu and Deisseroth, Karl", title = "Amygdala circuitry mediating reversible and bidirectional control of anxiety", journal = "Nature", publisher = 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