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Russell and Lomenick, Brett and Moradian, Annie and Prabhu, Siddharth and Sweredoski, Michael J. and Vander Lugt, Bryan and Verma, Rati and Deshaies, Raymond J.", title = "Quantitative measurement of the requirement of diverse protein degradation pathways in MHC class I peptide presentation", year = "2023", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230628-257055000.15", id = "https://authors.library.caltech.edu/records/na8tg-kw493", issn = "2375-2548", doi = "10.1126/sciadv.ade7890", volume = "9", number = "25", pmcid = "PMC10289651", pages = "eade7890" } @article{https://authors.library.caltech.edu/records/xnc4p-kns39, author = "Zhang, Yaru and Jost, Marco and Pak, Ryan A. and Lu, Daniel and Li, Jing and Lomenick, Brett and Garbis, Spiros D. and Li, Chi-Ming and Weissman, Jonathan S. and Lipford, James Russell and Deshaies, Raymond J.", title = "Adaptive exchange sustains cullin–RING ubiquitin ligase networks and proper licensing of DNA replication", year = "2022", url = "https://resolver.caltech.edu/CaltechAUTHORS:20230725-706009000.22", id = "https://authors.library.caltech.edu/records/xnc4p-kns39", issn = "0027-8424", doi = "10.1073/pnas.2205608119", volume = "119", number = "36", pmcid = "PMC9456757", pages = "Art. No. e2205608119" } @article{https://authors.library.caltech.edu/records/hkq8r-z1091, author = "Porras-Yakushi, Tanya R. and Reitsma, Justin M. and Sweredoski, Michael J. and Deshaies, Raymond J. and Hess, Sonja", title = "In depth proteomic analysis of proteasome inhibitors bortezomib, carfilzomib and MG132 reveals that mortality factor 4-like 1 (MORF4L1) protein ubiquitylation is negatively impacted", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210414-071610399", id = "https://authors.library.caltech.edu/records/hkq8r-z1091", issn = "1874-3919", doi = "10.1016/j.jprot.2021.104197", volume = "241", pages = "Art. No. 104197" } @article{https://authors.library.caltech.edu/records/5b58b-qz615, author = "Zhang, Gang and Li, Shan and Wang, Feng and Jones, Amanda C. and Goldberg, Alexander F. G. and Lin, Benjamin and Virgil, Scott and Stoltz, Brian M. and Deshaies, Raymond J. and Chou, Tsui-Fen", title = "A covalent p97/VCP ATPase inhibitor can overcome resistance to CB-5083 and NMS-873 in colorectal cancer cells", year = "2021", url = "https://resolver.caltech.edu/CaltechAUTHORS:20210104-164231600", id = "https://authors.library.caltech.edu/records/5b58b-qz615", issn = "0223-5234", doi = "10.1016/j.ejmech.2020.113148", volume = "213", pmcid = "PMC7954469", pages = "Art. 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No. 118729" } @article{https://authors.library.caltech.edu/records/wvrg9-pca56, author = "Reichermeier, Kurt M. and Straube, Ronny and Reitsma, Justin M. and Sweredoski, Michael J. and Rose, Christopher M. and Moradian, Annie and den Besten, Willem and Hinkle, Trent and Verschueren, Erik and Petzold, Georg and Thomä, Nicolas H. and Wertz, Ingrid E. and Deshaies, Raymond J. and Kirkpatrick, Donald S.", title = "PIKES Analysis Reveals Response to Degraders and Key Regulatory Mechanisms of the CRL4 Network", year = "2020", url = "https://resolver.caltech.edu/CaltechAUTHORS:20200122-081543072", id = "https://authors.library.caltech.edu/records/wvrg9-pca56", issn = "1097-2765", doi = "10.1016/j.molcel.2019.12.013", volume = "77", number = "5", pages = "1092-1106" } @article{https://authors.library.caltech.edu/records/xmm0f-3fw32, author = "Blythe, Emily E. and Gates, Stephanie N. and Deshaies, Raymond J. and Martin, Andreas", title = "Multisystem Proteinopathy Mutations in VCP/p97 Increase NPLOC4·UFD1L Binding and Substrate Processing", year = "2019", url = "https://resolver.caltech.edu/CaltechAUTHORS:20191014-113833407", id = "https://authors.library.caltech.edu/records/xmm0f-3fw32", issn = "0969-2126", doi = "10.1016/j.str.2019.09.011", volume = "27", number = "12", pmcid = "PMC6929323", pages = "1820-1829" } @article{https://authors.library.caltech.edu/records/4570v-77h57, author = "Li, Jing and Zhang, Yaru and Da Silva Sil Dos Santos, Bruno and Wang, Feng and Ma, Yuyong and Perez, Christian and Yang, Yanling and Peng, Junmin and Cohen, Seth M. and Chou, Tsui-Fen and Hilton, Stephen T. and Deshaies, Raymond J.", title = "Epidithiodiketopiperazines Inhibit Protein Degradation by Targeting Proteasome Deubiquitinase Rpn11", year = "2018", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180823-134532623", id = "https://authors.library.caltech.edu/records/4570v-77h57", issn = "2451-9456", doi = "10.1016/j.chembiol.2018.07.012", volume = "25", number = "11", pmcid = "PMC6309308", pages = "1350-1358" } @article{https://authors.library.caltech.edu/records/3f010-dkg51, author = "Verma, Rati and Reichermeier, Kurt M. and Burroughs, A. Maxwell and Oania, Robert S. and Reitsma, Justin M. and Aravind, L. and Deshaies, Raymond J.", title = "Vms1 and ANKZF1 peptidyl-tRNA hydrolases release nascent chains from stalled ribosomes", year = "2018", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180110-115638809", id = "https://authors.library.caltech.edu/records/3f010-dkg51", issn = "0028-0836", doi = "10.1038/s41586-018-0022-5", volume = "557", number = "7705", pmcid = "PMC6226276", pages = "446-451" } @article{https://authors.library.caltech.edu/records/gp19g-b5z02, author = "Lobanova, Ekaterina S. and Finkelstein, Stella and Li, Jing and Travis, Amanda M. and Hao, Ying and Klingeborn, Mikael and Skiba, Nikolai P. and Deshaies, Raymond J. and Arshavsky, Vadim Y.", title = "Increased proteasomal activity supports photoreceptor survival in inherited retinal degeneration", year = "2018", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180503-101314227", id = "https://authors.library.caltech.edu/records/gp19g-b5z02", issn = "2041-1723", doi = "10.1038/s41467-018-04117-8", volume = "9", pmcid = "PMC5928105", pages = "Art. 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J.", title = "Characterization of p97 mutations causing multisystem proteinopathy support a gain-of-function model for pathology", year = "2017", url = "https://resolver.caltech.edu/CaltechAUTHORS:20180321-142839561", id = "https://authors.library.caltech.edu/records/jhg19-3rm21", issn = "1059-1524", doi = "10.1091/mbc.E17-10-0618", volume = "28", number = "26", pages = "Art. 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No. e19105" } @article{https://authors.library.caltech.edu/records/zk36m-7pr16, author = "Mosadeghi, Ruzbeh and Reichermeier, Kurt M. and Winkler, Martin and Schreiber, Anne and Reitsma, Justin M. and Zhang, Yaru and Stengel, Florian and Cao, Junyue and Kim, Minsoo and Sweredoski, Michael J. and Hess, Sonja and Leitner, Alexander and Aebersold, Ruedi and Peter, Matthias and Deshaies, Raymond J. and Enchev, Radoslav I.", title = "Structural and kinetic analysis of the COP9-Signalosome activation and the cullin-RING ubiquitin ligase deneddylation cycle", year = "2016", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160405-075712117", id = "https://authors.library.caltech.edu/records/zk36m-7pr16", issn = "2050-084X", doi = "10.7554/eLife.12102", volume = "5", pmcid = "PMC4878873", pages = "Art. No. e12102" } @article{https://authors.library.caltech.edu/records/9krxd-7yd23, author = "Nguyen, Thang Van and Lee, J. Eugene and Sweredoski, Michael J. and Yang, Seung-Joo and Jeon, Seung-Je and Harrison, Joseph S. and Yim, Jung-Hyuk and Lee, Sang Ghil and Handa, Hiroshi and Kuhlman, Brian and Jeong, Ji-Seon and Reitsma, Justin M. and Park, Chul-Seung and Hess, Sonja and Deshaies, Raymond J.", title = "Glutamine Triggers Acetylation-Dependent Degradation of Glutamine Synthetase via the Thalidomide Receptor Cereblon", year = "2016", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160321-131029451", id = "https://authors.library.caltech.edu/records/9krxd-7yd23", issn = "1097-2765", doi = "10.1016/j.molcel.2016.02.032", volume = "61", number = "6", pmcid = "PMC4889030", pages = "809-820" } @article{https://authors.library.caltech.edu/records/ykjyb-08m93, author = "Banerjee, Sooiay and Bartesaghi, Alberto and Merk, Alan and Rao, Prashant and Bulfer, Stacie L. and Yan, Yongzhao and Green, Neal and Mroczkowski, Barbara and Neitz, R. Jeffrey and Wipf, Peter and Falconieri, Veronica and Deshaies, Raymond J. and Milne, Jacqueline L. S. and Huryn, Donna and Arkin, Michelle and Subramaniam, Sriram", title = "2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition", year = "2016", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160208-092709831", id = "https://authors.library.caltech.edu/records/ykjyb-08m93", issn = "0036-8075", doi = "10.1126/science.aad7974", volume = "351", number = "6275", pages = "871-875" } @article{https://authors.library.caltech.edu/records/w4wzh-67s17, author = "Alverez, Celeste and Bulfer, Stacie L. and Chakrasali, Ramappa and Chimenti, Michael. S. and Deshaies, Raymond J. and Green, Neal and Kelly, Mark and LaPorte, Matthew G. and Lewis, Taber S. and Liang, Mary and Moore, William J. and Neitz, R. Jeffrey and Peshkov, Vsevolod A. and Walters, Michael A. and Zhang, Feng and Arkin, Michelle R. and Wipf, Peter and Huryn, Donna M.", title = "Allosteric Indole Amide Inhibitors of p97: Identification of a Novel Probe of the Ubiquitin Pathway", year = "2016", url = "https://resolver.caltech.edu/CaltechAUTHORS:20160315-125347072", id = "https://authors.library.caltech.edu/records/w4wzh-67s17", issn = "1948-5875", doi = "10.1021/acsmedchemlett.5b00396", volume = "7", number = "2", pages = "182-187" } @article{https://authors.library.caltech.edu/records/qh2st-tmb86, author = "Deshaies, Raymond J.", title = "Protein degradation: Prime time for PROTACs", year = "2015", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150911-085528272", id = "https://authors.library.caltech.edu/records/qh2st-tmb86", issn = "1552-4450", doi = "10.1038/nchembio.1887", volume = "11", number = "9", pages = "634-635" } @article{https://authors.library.caltech.edu/records/nnk14-mvr07, author = "Pulvino, Mary and Chen, Luojing and Oleksyn, David and Li, Jing and Compitello, George and Rossi, Randy and Spence, Stephen and Balakrishnan, Vijaya and Jordan, Craig and Poligone, Brian and Casulo, Carla and Burack, Richard and Shapiro, Joel L. and Bernstein, Steven and Friedberg, Jonathan W. and Deshaies, Raymond J. and Land, Hartmut and Zhao, Jiyong", title = "Inhibition of COP9-signalosome (CSN) deneddylating activity and tumor growth of diffuse large B-cell lymphomas by doxycycline", year = "2015", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150706-111955387", id = "https://authors.library.caltech.edu/records/nnk14-mvr07", issn = "1949-2553", doi = "10.18632/oncotarget.4193", volume = "6", number = "17", pmcid = "PMC4558116", pages = "14796-14813" } @article{https://authors.library.caltech.edu/records/7hgsh-hvy79, author = "Fang, Nancy N. and Chan, Gerard T. and Zhu, Mang and Comyn, Sophie A. and Persaud, Avinash and Deshaies, Raymond J. and Rotin, Daniela and Gsponer, Joerg and Mayor, Thibault", title = "Rsp5/Nedd4 is the main ubiquitin ligase that targets cytosolic misfolded proteins following heat stress", year = "2014", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140915-125611389", id = "https://authors.library.caltech.edu/records/7hgsh-hvy79", issn = "1465-7392", doi = "10.1038/ncb3054", volume = "16", number = "12", pmcid = "PMC5224936", pages = "1227-1237" } @article{https://authors.library.caltech.edu/records/1v5vm-jcz32, author = "Deshaies, Raymond J.", title = "Proteotoxic crisis, the ubiquitin-proteasome system, and cancer therapy", year = "2014", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150122-083936041", id = "https://authors.library.caltech.edu/records/1v5vm-jcz32", issn = "1741-7007", doi = "10.1186/s12915-014-0094-0", volume = "12", pmcid = "PMC4226866", pages = "Art. No. 94" } @article{https://authors.library.caltech.edu/records/4exz9-bgp24, author = "Deshaies, Raymond J.", title = "Corralling a protein-degradation regulator", year = "2014", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140903-135522551", id = "https://authors.library.caltech.edu/records/4exz9-bgp24", issn = "0028-0836", doi = "10.1038/nature13644", volume = "512", number = "7513", pages = "145-146" } @article{https://authors.library.caltech.edu/records/6wvcy-70d51, author = "Chou, Tsui-Fen and Bulfer, Stacie L. and Weihl, Conrad C. and Li, Kelin and Lis, Lev G. and Walters, Michael A. and Schoenen, Frank J. and Lin, Henry J. and Deshaies, Raymond J. and Arkin, Michelle R.", title = "Specific Inhibition of p97/VCP ATPase and Kinetic Analysis Demonstrate Interaction between D1 and D2 ATPase domains", year = "2014", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140609-114312310", id = "https://authors.library.caltech.edu/records/6wvcy-70d51", issn = "0022-2836", doi = "10.1016/j.jmb.2014.05.022", volume = "426", number = "15", pmcid = "PMC4102644", pages = "2886-2899" } @article{https://authors.library.caltech.edu/records/abwrw-d2v51, author = "Deshaies, Raymond J.", title = "Structural biology: Corralling a protein-degradation regulator", year = "2014", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140728-083757319", id = "https://authors.library.caltech.edu/records/abwrw-d2v51", issn = "0028-0836", doi = "10.1038/nature13644" } @article{https://authors.library.caltech.edu/records/mefc4-tdr41, author = "Chan, Nickie C. and den Besten, Willem and Sweredoski, Michael J. and Hess, Sonja and Deshaies, Raymond J. and Chan, David C.", title = "Degradation of the Deubiquitinating Enzyme USP33 is Mediated by p97 and the Ubiquitin Ligase HERC2", year = "2014", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140604-082523933", id = "https://authors.library.caltech.edu/records/mefc4-tdr41", issn = "0021-9258", doi = "10.1074/jbc.M114.569392", volume = "289", number = "28", pmcid = "PMC4094088", pages = "19789-19798" } @article{https://authors.library.caltech.edu/records/s7fx1-vwn02, author = "Deshaies, Raymond and Chou, Tsui-Fen and Li, Jing and Mackinnon, Andy and Parlati, Francesco", title = "Exploiting protein homeostasis for cancer therapy", year = "2014", url = "https://resolver.caltech.edu/CaltechAUTHORS:20150205-100227097", id = "https://authors.library.caltech.edu/records/s7fx1-vwn02", issn = "0892-6638", volume = "28", number = "1", pages = "472.2" } @article{https://authors.library.caltech.edu/records/y6834-6k042, author = "Honarpour, Narimon and Rose, Christopher M. and Brumbaugh, Justin and Anderson, Jody and Graham, Robert L. J. and Sweredoski, Michael J. and Hess, Sonja and Coon, Joshua J. and Deshaies, Raymond J.", title = "F-box Protein FBXL16 Binds PP2A-B55α and Regulates Differentiation of Embryonic Stem Cells along the FLK1+ Lineage", year = "2014", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140417-141503413", id = "https://authors.library.caltech.edu/records/y6834-6k042", issn = "1535-9476", doi = "10.1074/mcp.M113.031765", volume = "13", number = "3", pmcid = "PMC3945908", pages = "780-791" } @article{https://authors.library.caltech.edu/records/96eqh-5ps11, author = "Radhakrishnan, Senthil K. and den Besten, Willem and Deshaies, Raymond J.", title = "p97-dependent retrotranslocation and proteolytic processing govern formation of active Nrf1 upon proteasome inhibition", year = "2014", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140225-085700599", id = "https://authors.library.caltech.edu/records/96eqh-5ps11", issn = "2050-084X", doi = "10.7554/elife.01856", volume = "3", pmcid = "PMC3896944", pages = "Art. No. e01856" } @article{https://authors.library.caltech.edu/records/bgtrk-bgq23, author = "Kolawa, Natalie and Sweredoski, Michael J. and Graham, Robert L. J. and Oania, Robert and Hess, Sonja and Deshaies, Raymond J.", title = "Perturbations to the Ubiquitin Conjugate Proteome in Yeast Δubx Mutants Identify Ubx2 as a Regulator of Membrane Lipid Composition", year = "2013", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140306-101045851", id = "https://authors.library.caltech.edu/records/bgtrk-bgq23", issn = "1535-9476", doi = "10.1074/mcp.M113.030163", volume = "12", number = "10", pmcid = "PMC3790291", pages = "2791-2803" } @article{https://authors.library.caltech.edu/records/xb45g-hw075, author = "Kurimchak, Alison and Haines, Dale S. and Garriga, Judit and Wu, Shufang and De Luca, Francesco and Sweredoski, Michael J. and Deshaies, Raymond J. and Hess, Sonja and Graña, Xavier", title = "Activation of p107 by Fibroblast Growth Factor, Which Is Essential for Chondrocyte Cell Cycle Exit, Is Mediated by the Protein Phosphatase 2A/B55α Holoenzyme", year = "2013", url = "https://resolver.caltech.edu/CaltechAUTHORS:20130904-105931353", id = "https://authors.library.caltech.edu/records/xb45g-hw075", issn = "0270-7306", doi = "10.1128/MCB.00082-13", volume = "33", number = "16", pmcid = "PMC3753905", pages = "3330-3342" } @article{https://authors.library.caltech.edu/records/1jp9m-9wp37, author = "Shi, Yihui and Liu, Xiaohe and Calaoagan, Joy and Samuelson, Steven and Chou, Tsui-Fen and Deshaies, Raymond J. and Sambucetti, Lidia C.", title = "Development of functional assays for p97/VCP inhibition", year = "2013", url = "https://resolver.caltech.edu/CaltechAUTHORS:20140325-082556135", id = "https://authors.library.caltech.edu/records/1jp9m-9wp37", issn = "0008-5472", doi = "10.1158/1538-7445.AM2013-2146", volume = "73", number = "8", pages = "Art. No. 2146" } @article{https://authors.library.caltech.edu/records/9seds-wpp69, author = "Pierce, Nathan W. and Lee, J. Eugene and Liu, Xing and Sweredoski, Michael J. and Graham, Robert L. J. and Larimore, Elizabeth A. and Rome, Michael and Zheng, Ning and Clurman, Bruce E. and Hess, Sonja and Shan, Shu-ou and Deshaies, Raymond J.", title = "Cand1 Promotes Assembly of New SCF Complexes through Dynamic Exchange of F Box Proteins", year = "2013", url = "https://resolver.caltech.edu/CaltechAUTHORS:20130517-081333288", id = "https://authors.library.caltech.edu/records/9seds-wpp69", issn = "0092-8674", doi = "10.1016/j.cell.2013.02.024", volume = "153", number = "1", pmcid = "PMC3656483", pages = "206-215" } @article{https://authors.library.caltech.edu/records/rqt83-93q76, author = "Chou, Tsui-Fen and Li, Kelin and Frankowski, Kevin J. and Schoenen, Frank J. and Deshaies, Raymond J.", title = "Structure–Activity Relationship Study Reveals ML240 and ML241 as Potent and Selective Inhibitors of p97 ATPase", year = "2013", url = "https://resolver.caltech.edu/CaltechAUTHORS:20130301-075535357", id = "https://authors.library.caltech.edu/records/rqt83-93q76", issn = "1860-7179", doi = "10.1002/cmdc.201200520", volume = "8", number = "2", pmcid = "PMC3662613", pages = "297-312" } @article{https://authors.library.caltech.edu/records/yjeaf-xm095, author = "Verma, Rati and Oania, Robert S. and Kolawa, Natalie J. and Deshaies, Raymond J.", title = "Cdc48/p97 promotes degradation of aberrant nascent polypeptides bound to the ribosome", year = "2013", url = "https://resolver.caltech.edu/CaltechAUTHORS:20130123-093059603", id = "https://authors.library.caltech.edu/records/yjeaf-xm095", issn = "2050-084X", doi = "10.7554/eLife.00308", volume = "2013", number = "2", pmcid = "PMC3552423", pages = "Art. No. e00308" } @article{https://authors.library.caltech.edu/records/n9x2n-29954, author = "Emberley, Ethan D. and Mosadeghi, Ruzbeh and Deshaies, Raymond J.", title = "Deconjugation of Nedd8 from Cul1 Is Directly Regulated by Skp1-F-box and Substrate, and the COP9 Signalosome Inhibits Deneddylated SCF by a Noncatalytic Mechanism", year = "2012", url = "https://resolver.caltech.edu/CaltechAUTHORS:20121009-110244928", id = "https://authors.library.caltech.edu/records/n9x2n-29954", issn = "0021-9258", doi = "10.1074/jbc.M112.352484", volume = "287", number = "35", pmcid = "PMC3436198", pages = "29679-29689" } @article{https://authors.library.caltech.edu/records/kpefn-0m097, author = "Oh, Younghoon and Chang, Kuang-Jung and Orlean, Peter and Wloka, Carsten and Deshaies, Raymond and Bi, Erfei", title = "Mitotic exit kinase Dbf2 directly phosphorylates chitin synthase Chs2 to regulate cytokinesis in budding yeast", year = "2012", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120807-123207702", id = "https://authors.library.caltech.edu/records/kpefn-0m097", issn = "1059-1524", doi = "10.1091/mbc.E12-01-0033", volume = "23", number = "13", pmcid = "PMC3386209", pages = "2445-2456" } @article{https://authors.library.caltech.edu/records/emagk-48678, author = "Haines, Dale S. and Lee, J. Eugene and Beauparlant, Stephen L. and Kyle, Dane B. and den Besten, Willem and Sweredoski, Michael J. and Graham, Robert L. J. and Hess, Sonja and Deshaies, Raymond J.", title = "Protein Interaction Profiling of the p97 Adaptor UBXD1 Points to a Role for the Complex in Modulating ERGIC-53 Trafficking", year = "2012", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120803-152029217", id = "https://authors.library.caltech.edu/records/emagk-48678", issn = "1535-9476", doi = "10.1074/mcp.M111.016444", volume = "11", number = "6", pmcid = "PMC3433925", pages = "Art. No. M111.016444" } @article{https://authors.library.caltech.edu/records/475qj-p8w74, author = "den Besten, Willem and Verma, Rati and Kleiger, Gary and Oania, Robert S. and Deshaies, Raymond J.", title = "NEDD8 links cullin-RING ubiquitin ligase function to the p97 pathway", year = "2012", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120601-100510892", id = "https://authors.library.caltech.edu/records/475qj-p8w74", issn = "1545-9985", doi = "10.1038/nsmb.2269", volume = "19", number = "5", pmcid = "PMC3348432", pages = "511-516" } @article{https://authors.library.caltech.edu/records/cwmf9-env95, author = "Sohn, Chang Ho and Agnew, Heather D. and Lee, J. Eugene and Sweredoski, Michael J. and Graham, Robert L. J. and Smith, Geoffrey T. and Hess, Sonja and Czerwieniec, Gregg and Loo, Joseph A. and Heath, James R. and Deshaies, Raymond J. and Beauchamp, J. L.", title = "Designer Reagents for Mass Spectrometry-Based Proteomics: Clickable Cross-Linkers for Elucidation of Protein Structures and Interactions", year = "2012", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120417-113310153", id = "https://authors.library.caltech.edu/records/cwmf9-env95", issn = "0003-2700", doi = "10.1021/ac202637n", volume = "84", number = "6", pmcid = "PMC3310289", pages = "2662-2669" } @article{https://authors.library.caltech.edu/records/t140f-9jz61, author = "Sohn, Chang Ho and Lee, J. Eugene and Sweredoski, Michael J. and Graham, Robert L. J. and Smith, Geoffrey T. and Hess, Sonja and Czerwieniec, Gregg and Loo, Joseph A. and Deshaies, Raymond J. and Beauchamp, J. L.", title = "Click Chemistry Facilitates Formation of Reporter Ions and Simplified Synthesis of Amine-Reactive Multiplexed Isobaric Tags for Protein Quantification", year = "2012", url = "https://resolver.caltech.edu/CaltechAUTHORS:20120202-074303275", id = "https://authors.library.caltech.edu/records/t140f-9jz61", issn = "0002-7863", doi = "10.1021/ja2099003", volume = "134", number = "5", pmcid = "PMC3668889", pages = "2672-2680" } @article{https://authors.library.caltech.edu/records/drs94-py641, author = "Chou, Tsui-Fen and Deshaies, Raymond J.", title = "Development of p97 AAA ATPase inhibitors", year = "2011", url = "https://resolver.caltech.edu/CaltechAUTHORS:20110930-072701050", id = "https://authors.library.caltech.edu/records/drs94-py641", issn = "1554-8627", doi = "10.4161/auto.7.9.16489", volume = "7", number = "9", pmcid = "PMC3210319", pages = "1091-1092" } @article{https://authors.library.caltech.edu/records/takrn-vr991, author = "Rabut, Gwenaël and Le Dez, Gaëlle and Verma, Rati and Makhnevych, Taras and Knebel, Axel and Kurz, Thimo and Boone, Charles and Deshaies, Raymond J. and Peter, Matthias", title = "The TFIIH Subunit Tfb3 Regulates Cullin Neddylation", year = "2011", url = "https://resolver.caltech.edu/CaltechAUTHORS:20110830-133501205", id = "https://authors.library.caltech.edu/records/takrn-vr991", issn = "1097-2765", doi = "10.1016/j.molcel.2011.05.032", volume = "43", number = "3", pmcid = "PMC3186349", pages = "488-495" } @article{https://authors.library.caltech.edu/records/h9q5b-acs85, author = "Gomez, Tara A. and Kolawa, Natalie and Gee, Marvin and Sweredoski, Michael J. and Deshaies, Raymond J.", title = "Identification of a functional docking site in the Rpn1 LRR domain for the UBA-UBL domain protein Ddi1", year = "2011", url = "https://resolver.caltech.edu/CaltechAUTHORS:20110705-093954428", id = "https://authors.library.caltech.edu/records/h9q5b-acs85", issn = "1741-7007", doi = "10.1186/1741-7007-9-33", volume = "9", pmcid = "PMC3126750", pages = "Art. No. 33" } @article{https://authors.library.caltech.edu/records/4n2xk-6xn86, author = "Chou, Tsui-Fen and Deshaies, Raymond J.", title = "Quantitative Cell-based Protein Degradation Assays to Identify and Classify Drugs That Target the Ubiquitin-Proteasome System", year = "2011", url = "https://resolver.caltech.edu/CaltechAUTHORS:20110606-105141967", id = "https://authors.library.caltech.edu/records/4n2xk-6xn86", issn = "0021-9258", doi = "10.1074/jbc.M110.215319", volume = "286", number = "19", pmcid = "PMC3089497", pages = "16546-16554" } @article{https://authors.library.caltech.edu/records/p6fbv-23968, author = "Lee, J. Eugene and Sweredoski, Michael J. and Graham, Robert L. J. and Kolawa, Natalie J. and Smith, Geoffrey T. and Hess, Sonja and Deshaies, Raymond J.", title = "The steady-state repertoire of human SCF Ubiquitin ligase complexes does not require ongoing Nedd8 conjugation", year = "2011", url = "https://resolver.caltech.edu/CaltechAUTHORS:20110526-100158794", id = "https://authors.library.caltech.edu/records/p6fbv-23968", issn = "1535-9476", doi = "10.1074/mcp.M110.006460", volume = "10", number = "5", pmcid = "PMC3098594", pages = "Art. No. M110.006460" } @article{https://authors.library.caltech.edu/records/crkwz-av525, author = "Saha, Anjanabha and Lewis, Steven and Kleiger, Gary and Kuhlman, Brian and Deshaies, Raymond J.", title = "Essential Role for Ubiquitin-Ubiquitin-Conjugating Enzyme Interaction in Ubiquitin Discharge from Cdc34 to Substrate", year = "2011", url = "https://resolver.caltech.edu/CaltechAUTHORS:20110502-103732644", id = "https://authors.library.caltech.edu/records/crkwz-av525", issn = "1097-2765", doi = "10.1016/j.molcel.2011.03.016", volume = "42", number = "1", pmcid = "PMC3091889", pages = "75-83" } @article{https://authors.library.caltech.edu/records/yvmyy-ta554, author = "Chou, Tsui-Fen and Brown, Steve J. and Minond, Dmitriy and Nordin, Brian E. and Li, Kelin and Jones, Amanda C. and Chase, Peter and Porubsky, Patrick R. and Stoltz, Brian M. and Schoenen, Frank J. and Patricelli, Matthew P. and Hodder, Peter and Rosen, Hugh and Deshaies, Raymond J.", title = "Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways", year = "2011", url = "https://resolver.caltech.edu/CaltechAUTHORS:20110414-085357247", id = "https://authors.library.caltech.edu/records/yvmyy-ta554", issn = "0027-8424", doi = "10.1073/pnas.1015312108", volume = "108", number = "12", pmcid = "PMC3064330", pages = "4834-4839" } @article{https://authors.library.caltech.edu/records/d7x5e-hjb39, author = "Verma, Rati and Oania, Robert and Fang, Ruihua and Smith, Geoffrey T. and Deshaies, Raymond J.", title = "Cdc48/p97 Mediates UV-Dependent Turnover of RNA Pol II", year = "2011", url = "https://resolver.caltech.edu/CaltechAUTHORS:20110202-104707165", id = "https://authors.library.caltech.edu/records/d7x5e-hjb39", issn = "1097-2765", doi = "10.1016/j.molcel.2010.12.017", volume = "41", number = "1", pmcid = "PMC3063307", pages = "82-92" } @article{https://authors.library.caltech.edu/records/ybxdz-c3060, author = "Tyrrell, An and Flick, Karin and Kleiger, Gary and Zhang, Hongwei and Deshaies, Raymond J. and Kaiser, Peter", title = "Physiologically relevant and portable tandem ubiquitin-binding domain stabilizes polyubiquitylated proteins", year = "2010", url = "https://resolver.caltech.edu/CaltechAUTHORS:20141120-133841734", id = "https://authors.library.caltech.edu/records/ybxdz-c3060", issn = "0027-8424", doi = "10.1073/pnas.1010648107", volume = "107", number = "46", pmcid = "PMC2993400", pages = "19796-19801" } @article{https://authors.library.caltech.edu/records/nfsj0-4a046, author = "Collins, Galen A. and Gomez, Tara Adele and Deshaies, Raymond J. and Tansey, William P.", title = "Combined chemical and genetic approach to inhibit proteolysis by the proteasome", year = "2010", url = "https://resolver.caltech.edu/CaltechAUTHORS:20101210-081023629", id = "https://authors.library.caltech.edu/records/nfsj0-4a046", issn = "0749-503X", doi = "10.1002/yea.1805", volume = "27", number = "11", pmcid = "PMC3566228", pages = "965-974" } 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S. and Young, Patrick and Beskow, Anne and Chan, Jefferson Y. and Deshaies, Raymond J.", title = "Transcription Factor Nrf1 Mediates the Proteasome Recovery Pathway after Proteasome Inhibition in Mammalian Cells", year = "2010", url = "https://resolver.caltech.edu/CaltechAUTHORS:20100610-122051580", id = "https://authors.library.caltech.edu/records/fm0zc-1d009", issn = "1097-2765", doi = "10.1016/j.molcel.2010.02.029", volume = "38", number = "1", pmcid = "PMC2874685", pages = "17-28" } @article{https://authors.library.caltech.edu/records/7f7q8-w0c55, author = "Kleiger, Gary and Hao, Bing and Mohl, Dane A. and Deshaies, Raymond J.", title = "The Acidic Tail of the Cdc34 Ubiquitin-conjugating Enzyme Functions in Both Binding to and Catalysis with Ubiquitin Ligase SCFC^(dc4*)", year = "2009", url = "https://resolver.caltech.edu/CaltechAUTHORS:20100121-133925591", id = "https://authors.library.caltech.edu/records/7f7q8-w0c55", issn = "0021-9258", doi = "10.1074/jbc.M109.058529", volume = "284", number = "52", pmcid = "PMC2794717", pages = "36012-36023" } @article{https://authors.library.caltech.edu/records/zazg2-s3b34, author = "Pierce, Nathan W. and Kleiger, Gary and Shan, Shu-ou and Deshaies, Raymond J.", title = "Detection of sequential polyubiquitylation on a millisecond timescale", year = "2009", url = "https://resolver.caltech.edu/CaltechAUTHORS:20091221-110503492", id = "https://authors.library.caltech.edu/records/zazg2-s3b34", issn = "0028-0836", doi = "10.1038/nature08595", volume = "462", number = "7273", pmcid = "PMC2791906", pages = "615-620" } @article{https://authors.library.caltech.edu/records/9j2ec-pbj70, author = "Kleiger, Gary and Saha, Anjanabha and Lewis, Steven and Kuhlman, Brian and Deshaies, Raymond J.", title = "Rapid E2-E3 Assembly and Disassembly Enable Processive Ubiquitylation of Cullin-RING Ubiquitin Ligase Substrates", year = "2009", url = "https://resolver.caltech.edu/CaltechAUTHORS:20091215-154909824", id = 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Russell and Deshaies, Raymond J. and Tansey, William P.", title = "Gal4 turnover and transcription activation", year = "2009", url = "https://resolver.caltech.edu/CaltechAUTHORS:20091022-111502275", id = "https://authors.library.caltech.edu/records/pk31x-0h429", issn = "0028-0836", doi = "10.1038/nature08406", volume = "461", number = "7265", pmcid = "PMC3072683", pages = "E7-E8" } @article{https://authors.library.caltech.edu/records/9w10e-b4002, author = "Deshaies, Raymond J. and Joazeiro, Claudio A. 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Hayes and Yates, John R., III and Wold, Barbara J. and Deshaies, Raymond J.", title = "Applicability of tandem affinity purification MudPIT to pathway proteomics in yeast", year = "2004", url = "https://resolver.caltech.edu/CaltechAUTHORS:GRAmcp04", id = "https://authors.library.caltech.edu/records/prghn-kb476", issn = "1535-9476", doi = "10.1074/mcp.M300099-MCP200", volume = "3", number = "3", pages = "226-237" } @article{https://authors.library.caltech.edu/records/p71zp-h0n84, author = "Wertz, Ingrid E. and O'Rourke, Karen M. and Zhang, Zemin and Dornan, David and Arnott, David and Deshaies, Raymond J. and Dixit, Vishva M.", title = "Human De-Etiolated-1 Regulates c-Jun by Assembling a CUL4A Ubiquitin Ligase", year = "2004", url = "https://resolver.caltech.edu/CaltechAUTHORS:20141125-123907609", id = "https://authors.library.caltech.edu/records/p71zp-h0n84", issn = "0036-8075", doi = "10.1126/science.1093549", volume = "303", number = "5662", pages = "1371-1374" } @article{https://authors.library.caltech.edu/records/86dy3-mf123, author = "Ambroggio, Xavier I. and Rees, Douglas C. and Deshaies, Raymond J.", title = "JAMM: A Metalloprotease-Like Zinc Site in the Proteasome and Signalosome", year = "2004", url = "https://resolver.caltech.edu/CaltechAUTHORS:AMBpb04", id = "https://authors.library.caltech.edu/records/86dy3-mf123", issn = "1544-9173", doi = "10.1371/journal.pbio.0020002", volume = "2", number = "1", pmcid = "PMC300881", pages = "113-119" } @article{https://authors.library.caltech.edu/records/6shde-qaj10, author = "Sakamoto, Kathleen M. and Kim, Kyung B. and Verma, Rati and Ransick, Andy and Stein, Bernd and Crews, Craig M. and Deshaies, Raymond J.", title = "Development of Protacs to Target Cancer-promoting Proteins for Ubiquitination and Degradation", year = "2003", url = "https://resolver.caltech.edu/CaltechAUTHORS:SAKmcp03", id = "https://authors.library.caltech.edu/records/6shde-qaj10", issn = "1535-9476", doi = "10.1074/mcp.T300009-MCP200", volume = "2", number = "12", pages = "1350-1358" } @article{https://authors.library.caltech.edu/records/708wv-nnn21, author = "Lipford, J. 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