- Dervan, Peter B. (2022) Skydiving
into the interface of chemistry and biology; Chemical &
Engineering News; Vol. 100; No. 10; 36-40
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polymerase II trapped on a molecular treadmill: Structural basis of
persistent transcriptional arrest by a minor groove DNA binder;
Proceedings of the National Academy of Sciences of the United States of
America; Vol. 119; No. 3; Art. No. e2114065119; PMCID PMC8784135; 10.1073/pnas.2114065119
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position substitution of hairpin pyrrole-imidazole polyamides imparts
distinct DNA-binding profiles across the human genome; PLoS ONE;
Vol. 15; No. 12; Art. No. e0243905; 10.1371/journal.pone.0243905
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of the transcriptional activity of ERRα with sequence-specific
DNA-binding polyamides; Medicinal Chemistry Research; Vol. 29;
No. 4; 607-616; PMCID PMC8455084; 10.1007/s00044-019-02493-4
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specific suppression of androgen receptor–DNA binding in vivo by a Py-Im
polyamide; Nucleic Acids Research; Vol. 47; No. 8; 3828-3835; PMCID
PMC6486638; 10.1093/nar/gkz153
- Dervan, Peter B. (2019) A
Personal Perspective on Chemical Biology: Before the Beginning;
Israel Journal of Chemistry; Vol. 59; No. 1-2; 71-83; 10.1002/ijch.201800171
- Dervan, Peter B. (2019) Ronald
Breslow Award for Achievement in Biomimetic Chemistry: David A.
Tirrell; Chemical and Engineering News; Vol. 97; No. 3; 51
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by a Pyrrole-Imidazole Polyamide Through Interference with DNA
Repair; International Journal of Radiation Oncology Biology Physics;
Vol. 102; No. 3, Supp.; e155; 10.1016/j.ijrobp.2018.07.604
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D. Roberts Special Issue; Journal of Physical Organic Chemistry;
Vol. 31; No. 8; Art. No. e3886; 10.1002/poc.3886
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with DNA repair after ionizing radiation by a pyrrole-imidazole
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PMC5929528; 10.1371/journal.pone.0196803
- Dervan, Peter B.; Kurmis, Alexis A.; et el. (2018) Molecular
Recognition of DNA by Py–Im Polyamides: From Discovery to Oncology;
ISBN 978-1-78262-992-4; DNA-targeting Molecules as Therapeutic Agents;
Royal Society of Chemistry: Cambridge; 298-331; 10.1039/9781788012928-00298
- Kurmis, Alexis and Dervan, Peter (2018) Molecular
recognition of DNA: From discovery to oncology
- Dervan, Peter B. (2018) Herbert
C. Brown Award for Creative Research in Synthetic Methods: Gregory C.
Fu; Chemical and Engineering News; Vol. 96; No. 2; 40
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basis for the initiation of eukaryotic transcription-coupled DNA
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pyrrole-imidazole polyamide is active against enzalutamide-resistant
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polymerase II senses obstruction in the DNA minor groove via a conserved
sensor motif; Proceedings of the National Academy of Sciences of the
United States of America; Vol. 113; No. 44; 12426-12431; PMCID
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- Dervan, Peter B. (2016) Ahmed
H. Zewail (1946-2016); Science; Vol. 353; No. 6304; 1103-1103; 10.1126/science.aai8466
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DNA Replication Forks at the Endogenous GAA Repeats Drive Repeat
Expansion in Friedreich’s Ataxia Cells; Cell Reports; Vol. 16;
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HRE-binding Py-Im polyamide impairs hypoxic signaling in tumors;
Molecular Cancer Therapeutics; Vol. 15; No. 4; 608-617; PMCID
PMC4873353; 10.1158/1535-7163.MCT-15-0719
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DNA-binding Molecule Targeting the Adaptive Hypoxic Response in Multiple
Myeloma has Potent Anti-tumor Activity; Molecular Cancer Research;
Vol. 14; No. 3; 253-266; PMCID PMC4794370; 10.1158/1541-7786.MCR-15-0361
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Repression of VCaP Xenografts by a Pyrrole-Imidazole Polyamide; PLoS
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by DNA, Binding Pyrrole, Imidazole Polyamides; International Journal
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sequence-specific DNA binding small molecule triggers the release of
immunogenic signals and phagocytosis in a model of B-cell lymphoma;
Quarterly Reviews of Biophysics; Vol. 48; No. 4; 453-464; PMCID
PMC4743504; 10.1017/S0033583515000104
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Repair Interference with Sequence Specific DNA Binding Pyrrole Imidazole
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Xenograft Uptake of a Pyrrole−Imidazole (Py-Im) Polyamide Varies as a
Function of Cell Line Grafted; Journal of Medicinal Chemistry; Vol.
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stress by Py–Im polyamides induces a non-canonical ATR-dependent
checkpoint response; Nucleic Acids Research; Vol. 42; No. 18;
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hypoxia-mediated gene transcription with a novel polyamide drug designed
to disrupt the HIF1α/β heterodimer binding overcomes resistance to
hypoxia in myeloma cell lines; Cancer Research; Vol. 74; No. 19
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C-14 labeled Py–Im polyamide localizes to a subcutaneous prostate cancer
tumor; Bioorganic and Medicinal Chemistry; Vol. 22; No. 16;
4371-4375; PMCID PMC4134956; 10.1016/j.bmc.2014.04.010
- Dervan, Peter B. (2014) Molecular
recognition of DNA by small molecules: Fundamentals to
applications
- Kang, JeenJoo S.; Meier, Jordan L.; et el. (2014) Design
of Sequence-Specific DNA Binding Molecules for DNA Methyltransferase
Inhibition; Journal of the American Chemical Society; Vol. 136;
No. 9; 3687-3694; PMCID PMC3985849; 10.1021/ja500211z
- Dervan, Peter B. (2014) Molecular
recognition of DNA by small molecules: Fundamentals to
applications
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by High Affinity Programmable Minor Groove Binders; International
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Toxicity of Hairpin Pyrrole-Imidazole Polyamides Varies with the Turn
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of a Py–Im Polyamide Targeted to the Estrogen Response Element;
Molecular Cancer Therapeutics; Vol. 12; No. 5; 675-684; PMCID
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activity of a pyrrole-imidazole polyamide in three tumor xenograft
models; Cancer Research; Vol. 73; No. 8; Art. No. 1130; 10.1158/1538-7445.AM2013-1130
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expression changes in tumor xenografts by Py-Im polyamides
- Edwards, Jonathan S.; Betts, Laurie; et el. (2013) Molecular
basis of antibiotic multiresistance transfer in Staphylococcus
aureus; Proceedings of the National Academy of Sciences of the
United States of America; Vol. 110; No. 8; 2804-2809; PMCID PMC3581901;
10.1073/pnas.1219701110
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of Cyclic Py-Im Polyamide Libraries; Journal of Organic Chemistry;
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Polyamides Distinguish Between Double-Helical DNA and RNA;
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the Design of Synthetic DNA-Binding Molecules with Massively Parallel
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expression changes in a tumor xenograft by a pyrrole-imidazole
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pharmacokinetic and toxicity analysis of pyrrole–imidazole polyamides in
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of Mismatch Repair Enzymes in GAA•TTC Triplet-repeat Expansion in
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structure determines accessibility of a hairpin polyamide–chlorambucil
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and Solubilization of Pyrrole−Imidazole Polyamide Aggregates;
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Assisted Synthesis of Py-Im Polyamides; Organic Letters; Vol. 14;
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of Py-Im Polyamides Depend on Architecture: Cyclic versus Linear;
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the cellular uptake of Py–Im polyamides through next-generation aryl
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of NF-κB-dependent gene transcription using programmable DNA minor
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the United States of America; Vol. 109; No. 4; 1023-1028; PMCID
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a DNA Binding Motif of the EVI1 Protein by a Pyrrole−Imidazole
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the Repertoire of Natural Product-Inspired Ring Pairs for Molecular
Recognition of DNA; Organic Letters; Vol. 13; No. 20; 5612-5615;
PMCID PMC3195311; 10.1021/ol202285y
- Dervan, P. B. (2010) Regulation
of gene expression by DNA binding Py-Im polyamides: Targeting
transcription factor-DNA interfaces
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Basis for Cyclic Py-Im Polyamide Allosteric Inhibition of Nuclear
Receptor Binding; Journal of the American Chemical Society; Vol.
132; No. 41; 14521-14529; PMCID PMC2954530; 10.1021/ja105068b
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at the C-Terminus To Improve Pyrrole−Imidazole Polyamide Activity in
Cell Culture; Journal of Medicinal Chemistry; Vol. 52; No. 23;
7380-7388; PMCID PMC2788682; 10.1021/jm900256f
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of DNA-binding dependent glucocorticoid receptor-mediated gene
expression; Proceedings of the National Academy of Sciences of the
United States of America; Vol. 106; No. 39; 16598-16603; PMCID
PMC2744631; 10.1073/pnas.0909192106
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Route to Py-Im Polyamide Macrocycles; Organic Letters; Vol. 11;
No. 16; 3590-3593; PMCID PMC2736337; 10.1021/ol901311m
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modulation of DNA by small molecules; Proceedings of the National
Academy of Sciences of the United States of America; Vol. 106; No. 32;
13175-13179; PMCID PMC2726366; 10.1073/pnas.0906532106
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sequence selectivity of hairpin polyamide turn units; Bioorganic and
Medicinal Chemistry Letters; Vol. 19; No. 14; 3919-3923; PMCID
PMC3062503; 10.1016/j.bmcl.2009.03.072
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detection of small molecule/DNA complexes employing a force-based and
label-free DNA-microarray; Biophysical Journal; Vol. 96; No. 11;
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pyrrole-imidazole polyamides targeted to the androgen response
element; Journal of the American Chemical Society; Vol. 131; No. 20;
7182-7188; PMCID PMC2689155; 10.1021/ja901309z
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synthesis of pyrrole-imidazole polyamides; Journal of the American
Chemical Society; Vol. 131; No. 20; 7175-7181; PMCID PMC2689157; 10.1021/ja901307m
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of a novel polyamide-based agent to inhibit EVI1 function; Blood;
Vol. 112; No. 11; 920
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the Concentration of Polyamide-Fluorescein Conjugates in Live Cells;
Bioorganic Medicinal Chemistry Letters Online; Vol. 18; No. 22; 5851-5;
10.1016/j.bmcl.2008.05.063
- Hsu, Carey F. and Dervan, Peter B. (2008) Quantitating
the concentration of Py-Im polyamide–fluorescein conjugates in live
cells; Bioorganic and Medicinal Chemistry Letters; Vol. 18; No. 22;
5851-5855; PMCID PMC2587135; 10.1016/j.bmcl.2008.05.063
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imaging of pyrrole-imidazole polyamides with positron emission
tomography; Proceedings of the National Academy of Sciences of the
United States of America; Vol. 105; No. 35; 13039-13044; PMCID
PMC2529060; 10.1073/pnas.0806308105
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generation hairpin polyamides with (R)-3,4-diaminobutyric acid turn
unit; Journal of the American Chemical Society; Vol. 130; No. 21;
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chemical wedges reveal the role of allosteric DNA modulation in
protein-DNA assembly; ACS Chemical Biology; Vol. 3; No. 4; 220-229;
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molecules targeting histone H4 as potential therapeutics for chronic
myelogenous leukemia; Molecular Cancer Therapeutics; Vol. 7; No. 4;
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multiple protein patterns on a single DNA nanostructure; Journal of
the American Chemical Society; Vol. 130; No. 2; 402-403; 10.1021/ja0772400
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acid-linked hairpin polyamides; Bioorganic and Medicinal Chemistry;
Vol. 15; No. 22; 6927-6936; PMCID PMC2140246; 10.1016/j.bmc.2007.07.019
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reach of linear protein-DNA dimerizers; Journal of the American
Chemical Society; Vol. 129; No. 45; 14026-14033; PMCID PMC2547995; 10.1021/ja075247b
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of “mirror-image” DNA by small molecules; Angewandte Chemie
International Edition; Vol. 46; No. 44; 8384-8387; 10.1002/anie.200703007
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single molecules on DNA nanostructures; Angewandte Chemie
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microarray profiling of DNA-binding molecules; Journal of the
American Chemical Society; Vol. 129; No. 40; 12310-12319; PMCID
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hypoxia-inducible transcription by disrupting the HIF-1-DNA
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of a Programmable DNA-Binding Small Molecule Library; Tetrahedron;
Vol. 63; No. 27; 6146-6151; PMCID PMC2151752; 10.1016/j.tet.2007.03.041
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of androgen receptor-mediated gene expression by a sequence-specific
DNA-binding polyamide; Proceedings of the National Academy of
Sciences of the United States of America; Vol. 104; No. 25; 10418-10423;
PMCID PMC1965528; 10.1073/pnas.0704217104
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of a Protein−DNA Dimerizer; Journal of the American Chemical
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Sequence-Specific dsDNA Binding Oligomers; Journal of the American
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oligomers targeting 5’-GGGG-3’ in the minor groove of DNA and NF-kappaB
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nuclear localization of DNA-binding polyamides; Nucleic Acids
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differences between α- and γ-diaminobutyric acid-linked hairpin
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No. 1; 307-316; PMCID PMC1802559; 10.1093/nar/gkl1025
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the limits of benzimidazole DNA-binding oligomers for the hypoxia
inducible factor (HIF) site; Bioorganic and Medicinal Chemistry;
Vol. 14; No. 24; 8539-8549; 10.1016/j.bmc.2006.08.028
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sequence-specific polyamides alleviate transcription inhibition
associated with long GAA·TTC repeats in Friedreich’s ataxia;
Proceedings of the National Academy of Sciences of the United States of
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two-hit mechanism for pre-mitotic arrest of cancer cell proliferation by
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the sequence-recognition profile of DNA-binding molecules;
Proceedings of the National Academy of Sciences of the United States of
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fluorescence detection of DNA by polyamide-thiazole orange
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DNA binding oligomers for control of transcription; Current
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of DNA binding by human estrogen-related receptor 2 and estrogen
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cancer proliferation by small-molecule gene regulation; Chemistry
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Reveal a Role for Repression in Latency within Resting T Cells of
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analysis of sequence-specific alkylation of DNA by pyrimidine
oligodeoxyribonucleotide-directed triple-helix formation;
Bioconjugate Chemistry; Vol. 8; No. 3; 354-364; 10.1021/bc970035x
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structure of an intramolecular DNA triplex containing an
N^7-glycosylated guanine which mimics a protonated cytosine;
Biochemistry; Vol. 36; No. 9; 2659-2668; 10.1021/bi962438a
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of the A·T/T·A Degeneracy of Pyrrole−Imidazole Polyamide Recognition in
the Minor Groove of DNA; Biochemistry; Vol. 35; No. 38; 12532-12537;
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Alkylation and Cleavage of DNA Mediated by Purine Motif Triple Helix
Formation; Biochemistry; Vol. 35; No. 38; 12313-9; 10.1021/bi9608469
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of a 5’-(A,T)GGG(A,T)_2-3’ Sequence in the Minor Groove of DNA by an
Eight-Ring Hairpin Polyamide; Journal of the American Chemical
Society; Vol. 118; No. 35; 8198-8206; 10.1021/ja9611598
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artificial sequence-specific DNA bending ligands; Proceedings of the
National Academy of Sciences of the United States of America; Vol. 93;
No. 18; 9510-9514; PMCID PMC38459
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of DNA by designed ligands at subnanomolar concentrations; Nature;
Vol. 382; No. 6591; 559-561; 10.1038/382559a0
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a hairpin polyamide in the minor groove of DNA: Sequence-specific
enthalpic discrimination; Proceedings of the National Academy of
Sciences of the United States of America; Vol. 93; No. 16; 8306-8311;
PMCID PMC38666
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triple-helix formation via a minor groove dimerization domain;
Journal of the American Chemical Society; Vol. 118; No. 28; 6778-6779;
10.1021/ja960831y
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site size limit of the 2:1 pyrrole-imidazole polyamide-DNA motif;
Proceedings of the National Academy of Sciences of the United States of
America; Vol. 93; No. 14; 6981-6985; PMCID PMC38920
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of sequence-specific recognition in the minor groove of DNA by
pyrrole-imidazole polyamides to 9-13 base pairs; Journal of the
American Chemical Society; Vol. 118; No. 26; 6160-6166; 10.1021/ja960726o
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of the hairpin polyamide design for recognition of the minor groove of
DNA; Journal of the American Chemical Society; Vol. 118; No. 26;
6147-6152; 10.1021/ja960721r
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of 5’-(A,T)GG(A,T)_2-3’ Sequences in the Minor Groove of DNA by Hairpin
Polyamides; Journal of the American Chemical Society; Vol. 118;
No. 26; 6153-6159; 10.1021/ja9607289
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phase synthesis of polyamides containing imidazole and pyrrole amino
acids; Journal of the American Chemical Society; Vol. 118; No. 26;
6141-6146; 10.1021/ja960720z
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recognition of DNA by a major and minor groove binding ligand;
Angewandte Chemie International Edition; Vol. 35; No. 13-14; 1487-1489;
10.1002/anie.199614871
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binding of a polyamide dimer and an oligonucleotide in the minor and
major grooves of DNA; Bioorganic and Medicinal Chemistry; Vol. 4;
No. 7; 1045-50; 10.1016/0968-0896(96)00089-2
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composition effects on the stabilities of triple helix formation by
oligonucleotides containing N7-deoxyguanosine; Nucleic Acids
Research; Vol. 24; No. 11; 1987-1991; PMCID PMC145894; 10.1093/nar/24.11.1987
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hairpin polyamide motif for sequence-specific recognition in the minor
groove of DNA; Chemistry and Biology; Vol. 3; No. 5; 369-377; 10.1016/S1074-5521(96)90120-9
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structure of a pyrimidine-purine-pyrimidine triplex containing the
sequence-specific intercalating non-natural base D_3; Journal of
Molecular Biology; Vol. 257; No. 5; 1052-1069; 10.1006/jmbi.1996.0223
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the recognition site of designed minor groove binding molecules;
Nature Structural Biology; Vol. 3; No. 4; 321-324; 10.1038/nsb0496-321
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polyamides for recognition in the minor groove of DNA; Proceedings
of the National Academy of Sciences of the United States of America;
Vol. 92; No. 22; 10389-10392; PMCID PMC40802
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Filaments Bind in the Minor Groove of Double-Stranded DNA;
Proceedings of the National Academy of Sciences of the United States of
America; Vol. 92; No. 22; 10393-10397; PMCID PMC40803
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filaments bind in the minor groove of double-stranded DNA;
Proceedings of the National Academy of Sciences of the United States of
America; Vol. 92; No. 22; 10393-10397; PMCID PMC40803
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one of the two DNA-bound orientations of AP-1 found in solution
cooperates with NFATp; Current Biology; Vol. 5; No. 8; 882-889; 10.1016/S0960-9822(95)00178-3
- Colocci, Natalia and Dervan, Peter B. (1995) Cooperative
Triple-Helix Formation at Adjacent DNA Sites: Sequence Composition
Dependence at the Junction; Journal of the American Chemical
Society; Vol. 117; No. 17; 4781-4787; 10.1021/ja00122a007
- Greenberg, William A. and Dervan, Peter B. (1995) Energetics
of Formation of Sixteen Triple Helical Complexes Which Vary at a Single
Position Within a Purine Motif; Journal of the American Chemical
Society; Vol. 117; No. 18; 5016-5022; 10.1021/ja00123a002
- Priestley, E. Scott and Dervan, Peter B. (1995) Sequence
Composition Effects on the Energetics of Triple Helix Formation by
Oligonucleotides Containing a Designed Mimic of Protonated Cytosine;
Journal of the American Chemical Society; Vol. 117; No. 17; 4761-4765;
10.1021/ja00122a004
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of an N^7-Glycosylated Purine Nucleoside for Recognition of GC Base
Pairs by Triple Helix Formation; Journal of the American Chemical
Society; Vol. 117; No. 9; 2661-2662; 10.1021/ja00114a036
- Mrksich, Milan and Dervan, Peter B. (1995) Recognition
in the Minor Groove of DNA at 5’-(A,T)GCGC(A,T)-3’ by a Four Ring
Tripeptide Dimer. Reversal of the Specificity of the Natural Product
Distamycin; Journal of the American Chemical Society; Vol. 117;
No. 12; 3325-3332; 10.1021/ja00117a002
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of Formation of Sixteen Triple Helical Complexes Which Vary at a Single
Position within a Pyrimidine Motif; Journal of the American Chemical
Society; Vol. 117; No. 4; 1187-1193; 10.1021/ja00109a001
- Singleton, Scott F. and Dervan, Peter B. (1994) Temperature
Dependence of the Energetics of Oligonucleotide-Directed Triple-Helix
Formation at a Single DNA Site; Journal of the American Chemical
Society; Vol. 116; No. 23; 10376-10382; 10.1021/ja00102a003
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of a G•C-Specific DNA Minor Groove-Binding Peptide; Science; Vol.
266; No. 5185; 646-650; 10.1126/science.7939719
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Temperature Dependence of Electron Transfer Rates in Fixed-Distance
Porphyrin-Quinone Model Systems; Journal of the American Chemical
Society; Vol. 116; No. 21; 9700-9709; 10.1021/ja00100a040
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Peptide Motif. A New Class of Oligopeptides for Sequence-Specific
Recognition in the Minor Groove of Double-Helical DNA; Journal of
the American Chemical Society; Vol. 116; No. 18; 7983-7988; 10.1021/ja00097a004
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RNA Regions in Eukaryotic Ribosomes That Are Accessible to
Methidiumpropyl-EDTA•Fe(II) and EDTA•Fe(II); Biochemistry; Vol. 33;
No. 33; 9831-9844
- Han, Hogyu and Dervan, Peter B. (1994) Different
conformational families of pyrimidine·purine·pyrimidine triple helices
depending on backbone composition; Nucleic Acids Research; Vol. 22;
No. 14; 2837-2844; PMCID PMC308255; 10.1093/nar/22.14.2837
- Staubli, Andrea B. and Dervan, Peter B. (1994) Sequence
specificity of the non-natural pyrido[2,3-d]pyrimidine nucleoside in
triple helix formation; Nucleic Acids Research; Vol. 22; No. 13;
2637-2642; PMCID PMC308221; 10.1093/nar/22.13.2637
- Hacia, Joseph G.; Dervan, Peter B.; et el. (1994) Inhibition
of Klenow fragment DNA polymerase on double-helical templates by
oligonucleotide-directed triple-helix formation; Biochemistry; Vol.
33; No. 20; 6192-6200; 10.1021/bi00186a019
- Han, Hogyu and Dervan, Peter B. (1994) Visualization
of RNA tertiary struture by RNA-EDTA·Fe(II) autocleavage: Analysis of
tRNAPhe with uridine-EDTA·Fe(II) at position 47; Proceedings of the
National Academy of Sciences of the United States of America; Vol. 91;
No. 11; 4955-4959; PMCID PMC43908
- Hacia, Joseph G.; Wold, Barbara J.; et el. (1994) Phosphorothioate
oligonucleotide-directed triple helix formation; Biochemistry; Vol.
33; No. 18; 5367-5369; 10.1021/bi00184a002
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of a hybrid protein containing the iron-binding ligand of bleomycin and
the DNA-binding domain of Hin; Bioconjugate Chemistry; Vol. 5;
No. 3; 242-247; 10.1021/bc00027a009
- Mrksich, Milan and Dervan, Peter B. (1994) Design
of a Covalent Peptide Heterodimer for Sequence-Specific Recognition in
the Minor Groove of Double-Helical DNA; Journal of the American
Chemical Society; Vol. 116; No. 8; 3663-3664; 10.1021/ja00087a088
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and dynamic characterization of the heterodimeric and homodimeric
complexes of distamycin and 1-methylimidazole-2-carboxamide-netropsin
bound to the minor groove of DNA; Biochemistry; Vol. 33; No. 10;
3055-3062; 10.1021/bi00176a039
- Colocci, Natalia and Dervan, Peter B. (1994) Cooperative
Binding of 8-mer Oligonucleotides Containing
5-(1-Propynyl)-2’-deoxyuridine to Adjacent DNA Sites by Triple-Helix
Formation; Journal of the American Chemical Society; Vol. 116;
No. 2; 785-786; 10.1021/ja00081a056
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association constants for oligonucleotide-directed triple helix
formation at single DNA sites: linkage to cation valence and
concentration; Biochemistry; Vol. 32; No. 48; 13171-13179; 10.1021/bi00211a028
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sequence specific recognition in the minor groove of DNA by covalent
peptide dimers: bis(pyridine-2-carboxamidonetropsin)(CH_2)_(3-6);
Journal of the American Chemical Society; Vol. 115; No. 22; 9892-9899;
10.1021/ja00075a004
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analysis of covalent peptide dimers,
bis(pyridine-2-carboxamidonetropsin)(CH_2)_(3-6), in complex with
5’-TGACT-3’ sites by two-dimensional NMR; Journal of the American
Chemical Society; Vol. 115; No. 22; 9900-9906; 10.1021/ja00075a005
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structural studies on a nonnatural deoxyribonucleoside which mediates
recognition of GC base pairs in pyrimidine•purine•pyrimidine DNA
triplexes; Biochemistry; Vol. 32; No. 41; 11228-11234; 10.1021/bi00092a037
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deoxyribonucleoside D_3 incorporated in an intramolecular DNA triplex
binds sequence-specifically by intercalation; Journal of the
American Chemical Society; Vol. 115; No. 17; 7908-7909; 10.1021/ja00070a059
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and preliminary X-ray analysis of the DNA binding domain of the Hin
recombinase with its DNA binding site; Journal of Molecular Biology;
Vol. 232; No. 3; 982-986; 10.1006/jmbi.1993.1443
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oligonucleotide-directed triple helix formation at adjacent DNA
sites; Journal of the American Chemical Society; Vol. 115; No. 11;
4468-4473; 10.1021/ja00064a008
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enzymic incorporation of an unnatural base,
N^6-(6-aminohexyl)isoguanosine, into RNA; Journal of the American
Chemical Society; Vol. 115; No. 11; 4461-4467; 10.1021/ja00064a007
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recognition of double helical RNA and RNA·DNA by triple helix
formation; Proceedings of the National Academy of Sciences of the
United States of America; Vol. 90; No. 9; 3806-3810; PMCID PMC46394; 10.1073/pnas.90.9.3806
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side-by-side heterodimer for sequence-specific recognition in the minor
groove of DNA by a distamycin/1-methylimidazole-2-carboxamide-netropsin
pair; Journal of the American Chemical Society; Vol. 115; No. 7;
2572-2576; 10.1021/ja00060a004
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novel gene containing a trinucleotide repeat that is expanded and
unstable on Huntington’s disease chromosomes; Cell; Vol. 72; No. 6;
971-83; 10.1016/0092-8674(93)90585-E
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recognition of CG base pairs by 2-deoxynebularine within the
purine•purine•pyrimidine triple-helix motif; Biochemistry; Vol. 32;
No. 9; 2177-85; 10.1021/bi00060a008
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of Cooperative Binding of Oligonucleotides with Discrete Dimerization
Domains to DNA by Triple Helix Formation; Proceedings of the
National Academy of Sciences of the United States of America; Vol. 90;
No. 4; 1179-1183; PMCID PMC45836; 10.1073/pnas.90.4.1179
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DNA chemical sequencing reaction; ISBN 978-0-12-182119-7;
Recombinant DNA; Academic Press: San Diego, CA; 222-227; 10.1016/0076-6879(93)18017-7
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dimerization of oligonucleotides binding cooperatively to DNA;
Journal of the American Chemical Society; Vol. 114; No. 27; 11006-11007;
10.1021/ja00053a073
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that a minor groove-binding peptide and a major groove-binding protein
can simultaneously occupy a common site on DNA; Biochemistry; Vol.
31; No. 45; 10969-10975; 10.1021/bi00160a005
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of peptides that bind in the minor groove of DNA at
5’-(A,T)G(A,T)C(A,T)-3’ sequences by a dimeric side-by-side motif;
Journal of the American Chemical Society; Vol. 114; No. 23; 8783-8794;
10.1021/ja00049a006
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of pH on the equilibrium association constants for
oligodeoxyribonucleotide-directed triple helix formation at single DNA
sites; Biochemistry; Vol. 31; No. 45; 10995-11003; 10.1021/bi00160a008
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of all four base pairs of double-helical DNA by triple-helix formation:
design of nonnatural deoxyribonucleosides for pyrimidine•purine base
pair binding; Journal of the American Chemical Society; Vol. 114;
No. 21; 7976-7982; 10.1021/ja00047a003
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oxidative cleavage of DNA by a designed metalloprotein,
nickel(II)•GGH(Hin139-190); Biochemistry; Vol. 31; No. 39; 9399-405;
10.1021/bi00154a011
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for the site-specific cleavage of megabase DNA; Nature; Vol. 359;
No. 6390; 87-88; 10.1038/359087a0
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of oligodeoxyribonucleotide-directed triple helix formation: an analysis
using quantitative affinity cleavage titration; Journal of the
American Chemical Society; Vol. 114; No. 18; 6957-6965; 10.1021/ja00044a002
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side-by-side dimeric motif for sequence-specific recognition in the
minor groove of DNA by the designed peptide 1-methylimidazole-2
carboxamide netropsin; Proceedings of the National Academy of
Sciences of the United States of America; Vol. 89; No. 16; 7586-7590;
PMCID PMC49755; 10.1073/pnas.89.16.7586
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double-strand alkylation and cleavage of DNA mediated by triple-helix
formation; Journal of the American Chemical Society; Vol. 114;
No. 15; 5934-5941; 10.1021/ja00041a005
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ligation of double-helical DNA by alternate-strand triple helix
formation; Nucleic Acids Research; Vol. 20; No. 12; 3005-3009; PMCID
PMC312430; 10.1093/nar/20.12.3005
- Beal, Peter A. and Dervan, Peter B. (1992) Recognition
of double helical DNA by alternate strand triple helix formation;
Journal of the American Chemical Society; Vol. 114; No. 13; 4976-4982;
10.1021/ja00039a004
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influence of single base triplet changes on the stability of a
Pur·Pur·Pyr triple helix determined by affinity cleaving; Nucleic
Acids Research; Vol. 20; No. 11; 2773-2776; PMCID PMC336921; 10.1093/nar/20.11.2773
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sequence effects within the pyrimidine triple-helix motif characterized
by affinity cleaving; Biochemistry; Vol. 31; No. 10; 2829-2834; 10.1021/bi00125a026
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of a nonnatural deoxyribonucleoside for recognition of GC base pairs by
oligonucleotide-directed triple helix formation; Journal of the
American Chemical Society; Vol. 114; No. 4; 1470-1478; 10.1021/ja00030a050
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of promoter-specific repression by triple-helical DNA complexes in a
eukaryotic cell-free transcription system; Biochemistry; Vol. 31;
No. 1; 70-81; 10.1021/bi00116a012
- Strobel, S. A. and Dervan, P. B. (1992) Triple
helix-mediated single-site enzymatic cleavage of megabase genomic
DNA; ISBN 978-0-12-182117-3; Recombinant DNA; Elsevier: New York,
NY; 309-321; 10.1016/0076-6879(92)16029-J
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cleavage of human chromosome 4 mediated by triple-helix formation;
Science; Vol. 254; No. 5038; 1639-1642; 10.1126/science.1836279
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of the Lac repressor DNA binding domain in complex with the left lac
operator half site characterized by affinity cleaving; Nucleic Acids
Research; Vol. 19; No. 19; 5233-5236; PMCID PMC328881; 10.1093/nar/19.19.5233
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of an abasic site on triple helix formation characterized by affinity
cleaving; Nucleic Acids Research; Vol. 19; No. 18; 4963-4965; PMCID
PMC328797; 10.1093/nar/19.18.4963
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sequence-specific ligation of double-helical DNA; Journal of the
American Chemical Society; Vol. 113; No. 19; 7447-7448; 10.1021/ja00019a066
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binding of oligonucleotides to DNA by triple helix formation:
dimerization via Watson-Crick hydrogen bonds; Journal of the
American Chemical Society; Vol. 113; No. 15; 5901-5902; 10.1021/ja00015a076
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Structural Motif for Recognition of DNA by Oligonucleotide-Directed
Triple-Helix Formation; Science; Vol. 251; No. 4999; 1360-1363; 10.1126/science.2003222
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enzymatic cleavage of yeast genomic DNA mediated by triple helix
formation; Nature; Vol. 350; No. 6314; 172-174; 10.1038/350172a0
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of protein-DNA complexes by affinity cleaving; ISBN
978-0-12-182109-8; Protein 3- DNA Interactions; Academic Press: San
Diego, CA; 497-515; 10.1016/0076-6879(91)08026-E
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alkylation of double-helical DNA by oligonucleotide-directed
triple-helix formation; Journal of the American Chemical Society;
Vol. 112; No. 25; 9428-9430; 10.1021/ja00181a075
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characterization of the stability and the melting behavior of a DNA
triplex: A spectroscopic and calorimetric study; Proceedings of the
National Academy of Sciences of the United States of America; Vol. 87;
No. 23; 9436-9440; PMCID PMC55180; 10.1073/pnas.87.23.9436
- Häner, Robert and Dervan, Peter B. (1990) Single-strand
DNA triple-helix formation; Biochemistry; Vol. 29; No. 42;
9761-9765; 10.1021/bi00494a001
- Graham, Kenneth S. and Dervan, Peter B. (1990) Structural
motif of the DNA binding domain of γδ-resolvase characterized by
affinity cleaving; Journal of Biological Chemistry; Vol. 265;
No. 27; 16534-16540
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analysis of oligodeoxyribonucleotide-directed triple-helix formation on
DNA; Biochemistry; Vol. 29; No. 37; 8820-8826; 10.1021/bi00489a045
- Sluka, James P.; Griffin, John H.; et el. (1990) Reagents
and methods for the solid-phase synthesis of protein-EDTA for use in
affinity cleaving; Journal of the American Chemical Society; Vol.
112; No. 17; 6369-6374; 10.1021/ja00173a027
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of minor-groove contacts for recognition of DNA by the binding domain of
Hin recombinase; Biochemistry; Vol. 29; No. 28; 6551-6561; 10.1021/bi00480a002
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of the putative recognition helix in the DNA-binding domain of Hin
recombinase complexed with the hix site; Biochemistry; Vol. 29;
No. 28; 6561-6567; 10.1021/bi00480a003
- Strobel, Scott A. and Dervan, Peter B. (1990) Site-Specific
Cleavage of a Yeast Chromosome by Oligonucleotide-Directed Triple-Helix
Formation; Science; Vol. 249; No. 4964; 73-75; 10.1126/science.2195655
- Mack, David P. and Dervan, Peter B. (1990) Nickel-mediated
sequence-specific oxidative cleavage of DNA by a designed
metalloprotein; Journal of the American Chemical Society; Vol. 112;
No. 11; 4604-4606; 10.1021/ja00167a102
- Oakley, Martha G. and Dervan, Peter B. (1990) Structural
motif of the GCN4 DNA binding domain characterized by affinity
cleaving; Science; Vol. 248; No. 4957; 847-850; 10.1126/science.2111578
- Horne, David A. and Dervan, Peter B. (1990) Recognition
of mixed-sequence duplex DNA by alternate-strand triple-helix
formation; Journal of the American Chemical Society; Vol. 112;
No. 6; 2435-2437; 10.1021/ja00162a063
- Dervan, Peter B. (1990) Chemical
methods for the site-specific cleavage of genomic DNA; ISBN
0-940030-29-2; Structure and Methods; Adenine Press; 37-49
- Breslauer, Kenneth J.; Ferrante, Robert; et el. (1990) The
Origins of the DNA Binding Affinity and Specificity of Minor Groove
Directed Ligands: Correlations of Thermodynamic and Structural Data;
ISBN 0-940030-22-5; Structure and Methods; Adenine Press; 273-289
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ligation of oligodeoxyribonucleotides on a duplex DNA template by
triple-helix formation; Journal of the American Chemical Society;
Vol. 111; No. 23; 8733-8735; 10.1021/ja00205a033
- Griffin, Linda C. and Dervan, Peter B. (1989) Recognition
of Thymine Adenine Base Pairs by Guanine in a Pyrimidine Triple Helix
Motif; Science; Vol. 245; No. 4921; 967-971; 10.1126/science.2549639
- Strobel, Scott A. and Dervan, Peter B. (1989) Cooperative
site specific binding of oligonucleotides to duplex DNA; Journal of
the American Chemical Society; Vol. 111; No. 18; 7286-7287; 10.1021/ja00200a073
- Maher, Louis J., III; Wold, Barbara; et el. (1989) Inhibition
of DNA binding proteins by oligonucleotide-directed triple helix
formation; Science; Vol. 245; No. 4919; 725-730; 10.1126/science.2549631
- Wang, Andrew H.-J.; Cottens, Sylvain; et el. (1989) Interactions
between a symmetrical minor groove binding compound and DNA
oligonucleotides: ^1H and ^(19)F NMR studies; Journal of
Biomolecular Structure and Dynamics; Vol. 7; No. 1; 101-117; 10.1080/07391102.1989.10507754
- Martello, Pamela A.; Bruzik, James P.; et el. (1989) Specific
activation of open complex formation at an Escherichia coli promoter by
oligo(N-methylpyrrolecarboxamide)s: effects of peptide length and
identification of DNA target sites; Biochemistry; Vol. 28; No. 10;
4455-61; 10.1021/bi00436a050
- Povsic, Thomas J. and Dervan, Peter B. (1989) Triple
helix formation by oligonucleotides on DNA extended to the physiological
pH range; Journal of the American Chemical Society; Vol. 111; No. 8;
3059-3061; 10.1021/ja00190a047
- Baker, Brenda F. and Dervan, Peter B. (1989) Sequence-specific
cleavage of DNA by N-bromoacetyldistamycin. Product and kinetic
analyses; Journal of the American Chemical Society; Vol. 111; No. 7;
2700-2712; 10.1021/ja00189a054
- Griffin, John H. and Dervan, Peter B. (1989) Metalloregulation
in the Sequence Specific Binding of Synthetic Molecules to DNA; ISBN
9780845126974; Metal ion homeostasis : molecular biology and chemistry;
Alan R. Liss: New York, NY; 21-30
- Dervan, Peter B. (1989) Oligonucleotide
recognition of double-helical DNA by triple-helix formation; ISBN
978-1-349-10871-8; Oligodeoxynucleotides: Antisense Inhibitors of Gene
Expression; CRC Press: Boca Raton, FL; 197-210; 10.1007/978-1-349-10869-5_10
- Strobel, Scott A.; Moser, Heinz E.; et el. (1988) Double
strand cleavage of genomic DNA at a single site by triple helix
formation; Journal of the American Chemical Society; Vol. 110;
No. 23; 7927-7929; 10.1021/ja00231a082
- Mack, David P.; Iverson, Brent L.; et el. (1988) Design
and chemical synthesis of a sequence-specific DNA-cleaving protein;
Journal of the American Chemical Society; Vol. 110; No. 22; 7572-7574;
10.1021/ja00230a067
- Iverson, Brent L. and Dervan, Peter B. (1988) Nonenzymatic
sequence-specific methyl transfer to single-stranded DNA;
Proceedings of the National Academy of Sciences of the United States of
America; Vol. 85; No. 13; 4615-4619; PMCID PMC280485
- Dervan, Peter B. (1988) John
D. Roberts; Aldrichimica Acta; Vol. 21; No. 3; 71-77
- Dervan, P. B. (1988) Sequence
Specific Recognition of Double Helical DNA. A Synthetic Approach;
ISBN 978-3-642-83386-1; Nucleic Acids and Molecular Biology;
Springer-Verlag: New York, NY; 49-64; 10.1007/978-3-642-83384-7_3
- Dervan, Peter B. (1988) Sequence
specific recognition and cleavage of double helical DNA
- Dervan, Peter B. (1988) Synthetic
Tools for Molecular Biology; ISBN 9780841214736; Biotechnology and
materials science : chemistry for the future; American Chemical Society:
Washington, DC; 21-29
- Youngquist, R. Scott and Dervan, Peter B. (1987) A
synthetic peptide binds 16 base pairs of A,T double helical DNA;
Journal of the American Chemical Society; Vol. 109; No. 24; 7564-7566;
10.1021/ja00258a070
- Sluka, James P.; Horvath, Suzanna J.; et el. (1987) Synthesis
of a sequence-specific DNA-cleaving peptide; Science; Vol. 238;
No. 4830; 1129-1132; 10.1126/science.3120311
- Moser, Heinz E. and Dervan, Peter B. (1987) Sequence-specific
cleavage of double helical DNA by triple helix formation; Science;
Vol. 238; No. 4827; 645-650; 10.1126/science.3118463
- Griffin, John H. and Dervan, Peter B. (1987) Metalloregulation
in the sequence specific binding of synthetic molecules to DNA;
Journal of the American Chemical Society; Vol. 109; No. 22; 6840-6842;
10.1021/ja00256a043
- Iverson, Brent L. and Dervan, Peter B. (1987) Adenine
specific DNA chemical sequencing reaction; Nucleic Acids Research;
Vol. 15; No. 19; 7823-7830; PMCID PMC306310; 10.1093/nar/15.19.7823
- Joran, A. D.; Leland, B. A.; et el. (1987) Effect
of exothermicity on electron transfer rates in photosynthetic molecular
models; Nature; Vol. 327; No. 6122; 508-511; 10.1038/327508a0
- Wade, Warren S. and Dervan, Peter B. (1987) Alteration
of the sequence specificity of distamycin on DNA by replacement of an
N-methylpyrrolecarboxamide with pyridine-2-carboxamide; Journal of
the American Chemical Society; Vol. 109; No. 5; 1574-1575; 10.1021/ja00239a050
- Iverson, Brent L. and Dervan, Peter B. (1987) Nonenzymatic
sequence-specific cleavage of single-stranded DNA to nucleotide
resolution. DNA methyl thioether probes; Journal of the American
Chemical Society; Vol. 109; No. 4; 1241-1243; 10.1021/ja00238a041
- Mendel, David and Dervan, Peter B. (1987) Hoogsteen
base pairs proximal and distal to echinomycin binding sites on DNA;
Proceedings of the National Academy of Sciences of the United States of
America; Vol. 84; No. 4; 910-914; PMCID PMC304329
- Dervan, Peter B. (1987) Design
of synthetic sequence specific DNA binding molecules; ISBN
9788877610232; Working Group on Molecular Mechanisms of Carcinogenic and
Antitumor Activity, October 21-25, 1986; Pontificiae Academiae
Scientiarum: Vatican City; 365-384
- Dervan, Peter B.; Youngquist, R. Scott; et el. (1987) Synthetic
sequence specific DNA binding molecules; ISBN 895736071;
Stereochemistry of organic and bioorganic transformations; VCH: New
York, NY; 221-234
- Griffin, John H. and Dervan, Peter B. (1986) Sequence-specific
recognition of right-handed double-helical DNA by (2S,3S)- and
(2R,3R)-dihydroxybis(netropsin)succinamide; Journal of the American
Chemical Society; Vol. 108; No. 16; 5008-5009; 10.1021/ja00276a052
- Dervan, Peter B. and Baker, Brenda F. (1986) Design
of sequence-specific DNA cleaving molecules: Comparison of
distamycin-EDTA • Fe(II) and N-bromoacetyldistamycin; Annals of the
New York Academy of Sciences; Vol. 471; 51-59; 10.1111/j.1749-6632.1986.tb48025.x
- Dervan, Peter B. (1986) Design
of Sequence-Specific DNA-Binding Molecules; Science; Vol. 232;
No. 4749; 464-471; 10.1126/science.2421408
- Dervan, P. B. and Sluka, J. P. (1986) Design
of sequence specific DNA binding molecules:
bis(distamycin)phenoxazone; ISBN 9780444989963; New Synthetic
Methodology and Functionally Interesting Compounds; Elsevier: New York,
NY; 307-322
- Baker, Brenda F. and Dervan, Peter B. (1985) Sequence-specific
cleavage of double-helical DNA. N-Bromoacetyldistamycin; Journal of
the American Chemical Society; Vol. 107; No. 26; 8266-8268; 10.1021/ja00312a079
- Leland, B. A.; Joran, A. D.; et el. (1985) Picosecond
Fluorescence Studies on Intramolecular Photochemical Electron Transfer
in Porphyrins Linked to Quinones at Two Different Fixed Distances;
Journal of Physical Chemistry; Vol. 89; No. 26; 5571-5573; 10.1021/j100272a002
- Berger, Carole L.; Cantor, Charles; et el. (1985) Comparison
of synthetic psoralen derivatives and 8-MOP in the inhibition of
lymphocyte proliferation; Annals of the New York Academy of
Sciences; Vol. 453; 80-90; 10.1111/j.1749-6632.1985.tb11800.x
- Youngquist, R. Scott and Dervan, Peter B. (1985) Sequence-specific
recognition of B DNA by bis(EDTA-distamycin)fumaramide; Journal of
the American Chemical Society; Vol. 107; No. 19; 5528-5529; 10.1021/ja00305a036
- Harshman, Keith D. and Dervan, Peter B. (1985) Molecular
recognition of B-DNA by Hoechst 33258; Nucleic Acids Research; Vol.
13; No. 13; 4825-4835; PMCID PMC321829; 10.1093/nar/13.13.4825
- Youngquist, R. Scott and Dervan, Peter B. (1985) Sequence-specific
recognition of B-DNA by oligo(N-methylpyrrolecarboxamide)s;
Proceedings of the National Academy of Sciences of the United States of
America; Vol. 82; No. 9; 2565-2569; PMCID PMC397604
- Dreyer, Geoffrey B. and Dervan, Peter B. (1985) Sequence-specific
cleavage of single-stranded DNA: Oligodeoxynucleotide-EDTA·Fe(II);
Proceedings of the National Academy of Sciences of the United States of
America; Vol. 82; No. 4; 968-972; PMCID PMC397174
- Joran, Alvin D.; Leland, Burt A.; et el. (1984) Models
for photochemical electron transfer at fixed distances.
Porphyrin-bicyclo[2.2.2]octane-quinone and
porphyrin-bisbicyclo[2.2.2]octane-quinone; Journal of the American
Chemical Society; Vol. 106; No. 20; 6090-6092; 10.1021/ja00332a062
- Van Dyke, Michael M. and Dervan, Peter B. (1984) Echinomycin
Binding Sites on DNA; Science; Vol. 225; No. 4667; 1122-1127; 10.1126/science.6089341
- Hertzberg, Robert P. and Dervan, Peter B. (1984) Cleavage
of DNA with methidiumpropyl-EDTA-iron(II): reaction conditions and
product analyses; Biochemistry; Vol. 23; No. 17; 3934-3945; 10.1021/bi00312a022
- Sylwester, Alan P. and Dervan, Peter B. (1984) Low-temperature
matrix isolation of the 1,1-diazene H_2NN. Electronic and infrared
characterization; Journal of the American Chemical Society; Vol.
106; No. 16; 4648-4650; 10.1021/ja00328a076
- Schultz, Peter G. and Dervan, Peter B. (1984) Distamycin
and penta-N-methylpyrrolecarboxamide binding sites on native DNA. A
comparison of methidiumpropyl-EDTA-Fe(II) footprinting and DNA affinity
cleaving; Journal of Biomolecular Structure and Dynamics; Vol. 1;
No. 5; 1133-1147; 10.1080/07391102.1984.10507508
- Taylor, John S.; Schultz, Peter G.; et el. (1984) DNA
affinity cleaving : Sequence specific cleavage of DNA by Distamycin-EDTA
• Fe(II) and EDTA-distamycin • Fe(II); Tetrahedron; Vol. 40; No. 3;
457-465; 10.1016/0040-4020(84)85050-4
- Schultz, P. G. and Dervan, P. B. (1983) Sequence-specific
double-strand cleavage of DNA by bis(EDTA-distamycin•Fe^(II)) and
EDTA-bis(distamycin)•Fe^(II); Journal of the American Chemical
Society; Vol. 105; No. 26; 7748-7750; 10.1021/ja00364a049
- Schultz, Peter G. and Dervan, Peter B. (1983) Sequence-specific
double-strand cleavage of DNA by
penta-N-methylpyrrolecarboxamide-EDTA·Fe(II); Proceedings of the
National Academy of Sciences of the United States of America; Vol. 80;
No. 22; 6834-6837; PMCID PMC390080
- Van Dyke, Michael W. and Dervan, Peter
- Methidiumpropyl-EDTA•Fe(II)
and DNase I footprinting report different small molecule binding site
sizes on DNA; Nucleic Acids Research; Vol. 11; No. 16; 5555-5567;
PMCID PMC326297; 10.1093/nar/11.16.5555
- Cartwright, Iain L.; Hertzberg, Robert P.; et el. (1983) Cleavage of
chromatin with methidiumpropyl-EDTA·iron(II); Proceedings of the
National Academy of Sciences of the United States of America; Vol. 80;
No. 11; 3213-3217; PMCID PMC394010
- Van Dyke, Michael W. and Dervan, Peter B. (1983) Chromomycin,
mithramycin, and olivomycin binding sites on heterogeneous DNA.
Footprinting with methidiumpropyl-EDTA•iron(II); Biochemistry; Vol.
22; No. 10; 2373-2377; 10.1021/bi00279a011
- Duan, Daniel C. and Dervan, Peter B. (1983) Evidence
for a stereospecific 1,2-elimination reaction in a 1,1-diazene.
Synthesis and decomposition of [N-phenyl(threo- and
erythro)-2-deuterio-1-methylpropyl)amino]nitrene; Journal of Organic
Chemistry; Vol. 48; No. 7; 970-976; 10.1021/jo00155a008
- Van Dyke, M. W. and Dervan, P. B. (1983) Footprinting
with MPE·Fe(II). Complementary-strand Analyses of Distamycin- and
Actinomycin-binding Sites on Heterogeneous DNA; Cold Spring Harbor
Symposia on Quantitative Biology; Vol. 47; No. Pt 1; 347-353; 10.1101/SQB.1983.047.01.040
- Van Dyke, M. W. and Dervan, P. B. (1983) Footprinting
with MPE•Fe(II). Complementary-strand analyses of distamycin- and
actinomycin-binding sites on heterogeneous DNA; Cold Spring Harbor
Symposia on Quantitative Biology; Vol. 47; 347-353; 10.1101/SQB.1983.047.01.040
- Schultz, Peter G.; Taylor, John S.; et el. (1982) Design
synthesis of a sequence-specific DNA cleaving molecule.
(Distamycin-EDTA)iron(II); Journal of the American Chemical Society;
Vol. 104; No. 24; 6861-6863; 10.1021/ja00388a101
- Schultz, Peter G. and Dervan, Peter B. (1982) Photochemistry
of 1,1-diazenes. Direct and sensitized photolyses of
N-(2,2,5,5-tetramethylpyrrolidyl)nitrene,
dl-N-(2,5-diethyl-2,5-dimethylpyrrolidyl)nitrene, and
N-(2,2,6,6-tetramethylpiperidyl)nitrene; Journal of the American
Chemical Society; Vol. 104; No. 24; 6660-6668; 10.1021/ja00388a031
- McIntyre, Daniel K. and Dervan, Peter
- 1,1-Di-tert-butyldiazene;
Journal of the American Chemical Society; Vol. 104; No. 23; 6466-6468;
10.1021/ja00387a061
- Van Dyke, Michael W.; Hertzberg, Robert P.; et el. (1982) Map of
distamycin, netropsin, and actinomycin binding sites on heterogeneous
DNA: DNA cleavage-inhibition patterns with
methidiumpropyl-EDTA·Fe(II); Proceedings of the National Academy of
Sciences of the United States of America; Vol. 79; No. 18; 5470-5474;
PMCID PMC346925
- Mitchell, Mark A. and Dervan, Peter B. (1982) Interhelical
DNA-DNA crosslinking. Bis(monoazidomethidium)octaoxahexacosanediamine: a
probe of packaged nucleic acid; Journal of the American Chemical
Society; Vol. 104; No. 15; 4265-4266; 10.1021/ja00379a045
- Hinsberg, William D., III; Schultz, Peter G.; et el. (1982) Direct
studies of 1,1-diazenes. Syntheses, infrared and electronic spectra, and
kinetics of the thermal decomposition of
N-(2,2,6,6-tetramethylpiperidyl)nitrene and
N-(2,2,5,5-tetramethylpyrrolidyl)nitrene; Journal of the American
Chemical Society; Vol. 104; No. 3; 766-773; 10.1021/ja00367a020
- Ikeda, Richard A. and Dervan, Peter B. (1982) Sequence-selective
inhibition of restriction endonucleases by the polyintercalator
bis(methidium)spermine; Journal of the American Chemical Society;
Vol. 104; No. 1; 296-297; 10.1021/ja00365a058
- Hertzberg, Robert P. and Dervan, Peter B. (1982) Cleavage
of double helical DNA by methidium-propyl-EDTA-iron(II); Journal of
the American Chemical Society; Vol. 104; No. 1; 313-315; 10.1021/ja00365a069
- Dervan, Peter B. and Dougherty, Dennis A. (1982) Nonconjugated
Diradicals; ISBN 471086614; Diradicals; John Wiley & Sons: New
York, NY; 107-149
- Dervan, Peter B.; Squillacote, Michael E.; et el. (1981) ^(15)N
NMR Spectrum of a 1,1-Diazene.
N-(2,2,6,6-Tetramethylpiperidyl)nitrene; Journal of the American
Chemical Society; Vol. 103; No. 5; 1120-1122; 10.1021/ja00395a021
- Schultz, Peter G. and Dervan, Peter B. (1981) Photochemistry
of a 1,1-diazene, N-(2,2,5,5-tetramethylpyrrolidinyl)nitrene;
Journal of the American Chemical Society; Vol. 103; No. 6; 1563-1564; 10.1021/ja00396a048
- Dervan, Peter B. and Santilli, Donald S. (1980) Synthesis
and thermal decomposition of cis-3,4,5,6-tetrahydropyridazine-3,4-d2.
Relative rates of rotation, cleavage, and closure for
tetramethylene; Journal of the American Chemical Society; Vol. 102;
No. 11; 3863-3870; 10.1021/ja00531a031
- Schultz, Peter G. and Dervan, Peter B. (1980) Synthesis
and direct spectroscopic observation of
N-(2,2,5,5-tetramethylpyrrolidinyl)nitrene. Comparison of five- and
six-membered cyclic 1,1-dialkyldiazenes; Journal of the American
Chemical Society; Vol. 102; No. 2; 878-880; 10.1021/ja00522a090
- Hinsberg, William D., III and Dervan, Peter B. (1979) Kinetics
of the thermal decomposition of a 1,1-dialkyldiazene,
N-(2,2,6,6-tetramethylpiperidyl)nitrene; Journal of the American
Chemical Society; Vol. 101; No. 20; 6142-6144; 10.1021/ja00514a058
- Becker, Michael McClellan and Dervan, Peter B. (1979) Molecular
recognition of nucleic acid by small molecules. Binding affinity and
structural specificity of bis(methidium)spermine; Journal of the
American Chemical Society; Vol. 101; No. 13; 3664-3666; 10.1021/ja00507a046
- Dervan, Peter B. and Jones, Carol R. (1979) Syntheses
and Decomposition of meso- and dl-2,3-Dimethylsuccinyl and cis- and
trans-1,2-Hexahydrophthaloyl Peroxides; Journal of Organic
Chemistry; Vol. 44; No. 13; 2116-2123; 10.1021/jo01327a016
- Santilli, Donald S. and Dervan, Peter B. (1979) Thermal
decomposition of cis-tetrahydropyridazine-3,4-d_2. Relative rates of
rotation, cleavage, and closure for tetramethylene; Journal of the
American Chemical Society; Vol. 101; No. 13; 3663-3664; 10.1021/ja00507a045
- Dervan, Peter B. and Uyehara, Tadao (1979) Stereochemical
tests of cyclic 1,1-dialkyldiazene fragmentation reactions. Thermal
decomposition of N-(cis-(and trans-)2,3-(and
2,5-)dimethylpyrrolidine)nitrenes; Journal of the American Chemical
Society; Vol. 101; No. 8; 2076-2082; 10.1021/ja00502a023
- Dervan, Peter B.; Uyehara, Tadao; et el. (1979) Experimental
determination of the relative rates of rotation, cleavage, closure, and
1,5-hydrogen shift for 3-methyl-1,4-pentanediyl. Evidence for 1,4
biradicals as common intermediates from different precursors, 3,4-(and
3,6-)dimethyl-3,4,5,6-tetrahydropyridazines and
1,2-dimethylcyclobutanes; Journal of the American Chemical Society;
Vol. 101; No. 8; 2069-2075; 10.1021/ja00502a022
- Dervan, Peter B. and Becker, Michael M. (1978) Molecular
recognition of DNA by small molecules. Synthesis of
bis(methidium)spermine, a DNA polyintercalating molecule; Journal of
the American Chemical Society; Vol. 100; No. 6; 1968-1970; 10.1021/ja00474a075
- Hinsberg, William D., III and Dervan, Peter B. (1978) Synthesis
and direct spectroscopic observation of a 1,1-dialkyldiazene. Infrared
and electronic spectrum of N-(2,2,6,6-tetramethylpiperidyl)nitrene;
Journal of the American Chemical Society; Vol. 100; No. 5; 1608-1610; 10.1021/ja00473a051
- Jones, Carol R. and Dervan, Peter B. (1977) Six-membered
cyclic diacyl peroxide fragmentations. Thermal decomposition of meso-
and dl-2,3-dimethylsuccinoyl peroxides; Journal of the American
Chemical Society; Vol. 99; No. 20; 6772-6774; 10.1021/ja00462a058
- Shippey, Michael A. and Dervan, Peter B. (1977) Trimethylsilyl
anions. Direct synthesis of trimethylsilylbenzenes; Journal of
Organic Chemistry; Vol. 42; No. 15; 2654-2655; 10.1021/jo00435a037
- Berson, Jerome A.; Dervan, Peter B.; et el. (1976) Formation
and thermal rearrangements of some dimers of butadiene and piperylene.
Tests of the validity of thermochemical-kinetic arguments for
identification of common biradical intermediates; Journal of the
American Chemical Society; Vol. 98; No. 19; 5937-5968; 10.1021/ja00435a031
- Dervan, Peter B. and Uyehara, Tadao (1976) A
stereochemical test of similarly substituted tetramethylenediazene and
cyclic azo decompositions in the gas phase at the same temperature;
Journal of the American Chemical Society; Vol. 98; No. 7; 2003-2005; 10.1021/ja00423a078
- Dervan, Peter B. and Uyehara, Tadao (1976) Thermal
decomposition of cis- and trans-3,4- and
-3,6-dimethyl-3,4,5,6-tetrahydropyridazines. Evidence against the hot
diradical postulate for azo decompositions; Journal of the American
Chemical Society; Vol. 98; No. 5; 1262-1264; 10.1021/ja00421a037
- Dervan, Peter B. and Shippey, Michael
- Trimethylsilylpotassium.
Deoxygenation of epoxides with inversion of stereochemistry; Journal
of the American Chemical Society; Vol. 98; No. 5; 1265-1267; 10.1021/ja00421a039
- Dervan, Peter B. and Uyehara, Tadao (1976) 7-Azabicyclo[2.2.1]heptane
N-Imide as an Intermediate in the Thermal Decomposition of
N-Amino-7-Azabicyclo[2.2.1]heptane and the Corresponding
Benzenesulphonamide; Journal of the Chemical Society. Chemical
Communications; Vol. 1976; No. 12; 469-470; 10.1039/C39760000469
- Berson, Jerome A. and Dervan, Peter B. (1973) Mechanistic
analysis of the four pathways in the 1,3-sigmatropic rearrangements of
trans-1,2-trans, trans- and
trans-1,2-cis,trans-dipropenylcyclobutane; Journal of the American
Chemical Society; Vol. 95; No. 1; 269-270; 10.1021/ja00782a062
- Berson, Jerome A. and Dervan, Peter B. (1973) Rearrangement
of trans-1,2-divinylcyclobutane and the energy surface of the dimers of
butadiene; Journal of the American Chemical Society; Vol. 95; No. 1;
267-269; 10.1021/ja00782a061
- Berson, Jerome A. and Dervan, Peter B. (1972) Stereodistal
Cope rearrangement of trans-1,2-dialkenylcyclobutanes; Journal of
the American Chemical Society; Vol. 94; No. 25; 8949-8950; 10.1021/ja00780a074
- Berson, Jerome A. and Dervan, Peter B. (1972) Incremental
substituent effects leading to steric blockade of the boat-like
six-center Cope rearrangement of cis-1,2-dialkenylcyclobutanes;
Journal of the American Chemical Society; Vol. 94; No. 21; 7597-7598; 10.1021/ja00776a064
- Berson, Jerome A.; Dervan, Peter B.; et el. (1972) Stereospecific
double rearrangement of trans-3,4-dimethyl-cis,trans-cycloocta-1,5-diene
to cis-3,4-dimethyl-cis,cis-cycloocta-1,5-diene; Journal of the
American Chemical Society; Vol. 94; No. 21; 7598-7599; 10.1021/ja00776a065
- Bennett, O. Francis; Bouchard, M. J.; et el. (1972) Hydroxide
displacement of the sulfone linkage in thioxanthen-9-one 10,10-dioxides
to benzophenone-2’-hydroxy-2-sulfinic acids. Intramolecular cyclization
to xanthones; Journal of Organic Chemistry; Vol. 37; No. 9;
1356-1359; 10.1021/jo00974a015