Mitachi, Katsuhiko; Mingle, David et al. (2022) Concise Synthesis of Tunicamycin V and Discovery of a Cytostatic DPAGT1 Inhibitor Angewandte Chemie International Edition; Vol. 61; No. 31;
Fry, Michelle Y.; Najdrova, Vladimira et al. (2022) Structurally derived universal mechanism for the catalytic cycle of the tail-anchored targeting factor Get3 Nature Structural & Molecular Biology; Vol. 29; No. 8;
Fry, Michelle; Najdrova, Vladimira et al. (2021) Structural characterization of the catalytic cycle of the chaperone Get3 from a human pathogen Protein Science; Vol. 30; No. S1; 35th Anniversary Symposium of The Protein Society, 7-14 July 2021 , [Online Only]
Fry, Michelle Y.; Saladi, Shyam M. et al. (2021) Sequence-based features that are determinant for tail-anchored membrane protein sorting in eukaryotes Traffic; Vol. 22; No. 9;
Fry, Michelle Y.; Saladi, Shyam M. et al. (2021) The STI1-domain is a flexible alpha‐helical fold with a hydrophobic groove Protein Science; Vol. 30; No. 4;
Lin, Ku-Feng; Fry, Michelle Y. et al. (2021) Molecular basis of tail-anchored integral membrane protein recognition by the cochaperone Sgt2 Journal of Biological Chemistry; Vol. 296;
Mitachi, Katsuhiko; Kansal, Rita G. et al. (2020) DPAGT1 Inhibitors of Capuramycin Analogues and Their Antimigratory Activities of Solid Tumors Journal of Medicinal Chemistry; Vol. 63; No. 19;
Mitachi, Katsuhiko; Yun, Hyun Gi et al. (2020) Substrate Tolerance of Bacterial Glycosyltransferase MurG: Novel Fluorescence-based Assays ACS Infectious Diseases; Vol. 6; No. 6;
Mitachi, Katsuhiko; Kurosu, Shou M. et al. (2019) A practical synthesis of a novel DPAGT1 inhibitor, aminouridyl phenoxypiperidinbenzyl butanamide (APPB) for in vivo studies MethodsX; Vol. 6;
Mitachi, Katsuhiko; Kurosu, Shou M. et al. (2019) Semisynthesis of an Anticancer DPAGT1 Inhibitor from a Muraymycin Biosynthetic Intermediate Organic Letters; Vol. 21; No. 4;
Saladi, Shyam M.; Javed, Nauman et al. (2018) A statistical model for improved membrane protein expression using sequence-derived features Journal of Biological Chemistry; Vol. 293; No. 13;
Mitachi, Katsuhiko; Yun, Hyun Gi et al. (2018) Novel FR-900493 Analogues That Inhibit the Outgrowth of Clostridium difficile Spores ACS Omega; Vol. 3; No. 2;
Fry, Michelle Y.; Clemons, William M., Jr. (2018) Complexity in targeting membrane proteins Science; Vol. 359; No. 6374;
Niesen, Michiel J. M.; Marshall, Stephen S. et al. (2017) Improving membrane protein expression by optimizing integration efficiency Journal of Biological Chemistry; Vol. 292; No. 47;
Mock, Jee-Young; Xu, Yue et al. (2017) Structural basis for regulation of the nucleo-cytoplasmic distribution of Bag6 by TRC35 Proceedings of the National Academy of Sciences of the United States of America; Vol. 114; No. 44;
Schulte, Samuel J.; Saladi, Shyam et al. (2017) Predicting Membrane Protein Expression in Yeast from Sequence-Derived Features Biophysical Journal; Vol. 112; No. 3; 58th Annual Meeting of the Biophysical-Society, 15-19 February 2014 , San Francisco, CA
Clemons, Bil (2017) Solving the Membrane Protein Expression Problem Biophysical Journal; Vol. 112; No. 3; 58th Annual Meeting of the Biophysical-Society, February 15-19, 2014 , San Francisco, CA
Saladi, Shyam; Chu, Alexander E. et al. (2017) Statistical Models Robustly Predict Membrane Protein Expression in E. Coli Biophysical Journal; Vol. 112; No. 3; 58th Annual Meeting of the Biophysical-Society, 15-19 February 2014 , San Francisco, CA
Chu, Alexander E.; Saladi, Shyam M. et al. (2017) Towards a Universal Characterization of the Membrane Protein Expression Landscape Biophysical Journal; Vol. 112; No. 3, Supp. 1; 61st Annual Meeting of the Biophysical-Society, 11-15 February 2017 , New Orleans, LA
Yun, Hyun Gi; Jang, Kyoung-Soon et al. (2016) The Structure of the UDP-Glc/GlcNAc 4-Epimerase from the Human Pathogen Campylobacter jejuni Glycobiology; Vol. 26; No. 12; 2016 Annual Meeting of the Society-for-Glycobiology, 19-22 November 2016 , New Orleans, LA
Marshall, Stephen S.; Niesen, Michiel J. M. et al. (2016) A Link between Integral Membrane Protein Expression and Simulated Integration Efficiency Cell Reports; Vol. 16; No. 8;
Saladi, Shyam M.; Javed, Nauman et al. (2016) A Machine Learning Approach to Heterologous Membrane Protein Overexpression Biophysical Journal; Vol. 110; No. 3; 60th Annual Meeting of the Biophysical-Society, 27 February-2 March 2016 , Los Angeles, CA
Lin, Ku-Feng; Clemons, William M. (2016) Promiscuous Binding of Membrane Proteins on Flexible Co-Chaperones, Yeast Sgt2 and Human SGTA Biophysical Journal; Vol. 110; No. 3; 60th Annual Meeting of the Biophysical-Society, February 27-March 2, 2016 , Los Angeles, CA
Gristick, Harry B.; Rome, Michael E. et al. (2015) Mechanism of assembly of a substrate-transfer complex during tail-anchored protein targeting Journal of Biological Chemistry; Vol. 290; No. 50;
Jang, Kyoung-Soon; Nani, Roger R. et al. (2015) A cationic cysteine-hydrazide as an enrichment tool for the mass spectrometric characterization of bacterial free oligosaccharides Analytical and Bioanalytical Chemistry; Vol. 407; No. 20;
Mock, Jee-Young; Clemons, William M., Jr. (2015) Capturing the signal eLife; Vol. 2015; No. 4;
Mitachi, Katsuhiko; Siricilla, Shajila et al. (2015) Chemoenzymatic syntheses of water-soluble lipid I fluorescent probes Tetrahedron Letters; Vol. 56; No. 23;
Mock, Jee-Young; Chartron, Justin William et al. (2015) Bag6 complex contains a minimal tail-anchor–targeting module and a mock BAG domain Proceedings of the National Academy of Sciences of the United States of America; Vol. 112; No. 1;
Müller, Axel; Beeby, Morgan et al. (2014) Ultrastructure and complex polar architecture of the human pathogen Campylobacter jejuni MicrobiologyOpen; Vol. 3; No. 5;
Gristick, Harry B.; Rao, Meera et al. (2014) Crystal structure of ATP-bound Get3–Get4–Get5 complex reveals regulation of Get3 by Get4 Nature Structural & Molecular Biology; Vol. 21; No. 5;
Gristick, Harry; Rao, Meera et al. (2014) The structure of a tail-anchor membrane protein-binding complex reveals the regulation of Get3 by Get4 FASEB Journal; Vol. 28; No. 1;
Jang, Kyoung-Soon; Sweredoski, Michael J. et al. (2014) Comprehensive proteomic profiling of outer membrane vesicles from Campylobacter jejuni Journal of Proteomics; Vol. 98;
Liu, Yanfen; Soetandyo, Nia et al. (2014) USP13 antagonizes gp78 to maintain functionality of a chaperone in ER-associated degradation eLife; Vol. 2014; No. 3;
Rome, Michael E.; Rao, Meera et al. (2013) Precise timing of ATPase activation drives targeting of tail-anchored proteins Proceedings of the National Academy of Sciences of the United States of America; Vol. 110; No. 19;
Ramasamy, Sureshkumar; Abrol, Ravinder et al. (2013) The Glove-like Structure of the Conserved Membrane Protein TatC Provides Insight into Signal Sequence Recognition in Twin-Arginine Translocation Structure; Vol. 21; No. 5;
Rao, Meera; Rome, Michael E. et al. (2013) Precise Timing of ATPase Activation Drives Targeting of Tail-Anchored Proteins Biophysical Journal; Vol. 104; No. 2; 57th Annual Meeting of the Biophysical-Society, February 2-6, 2013 , Philadelphia, PA
Chartron, Justin W.; VanderVelde, David G. et al. (2012) Structures of the Sgt2/SGTA Dimerization Domain with the Get5/UBL4A UBL Domain Reveal an Interaction that Forms a Conserved Dynamic Interface Cell Reports; Vol. 2; No. 6;
Tanaka, Shiho; Clemons, William M., Jr. (2012) Minimal requirements for inhibition of MraY by lysis protein E from bacteriophage ΦX174 Molecular Microbiology; Vol. 85; No. 5;
Clemons, Bil; Chartron, Justin et al. (2012) Higher order assemblies in the GET membrane protein-targeting pathway Protein Science; Vol. 21; No. S1; 26th Annual Symposium of the Protein-Society, August 5-8, 2012 , San Diego, CA
Mock, Jeeyoung; Chartron, Justin et al. (2012) The Structural and Biochemical Characterization of Members of the Mammalian TA Protein Sorting Complex Protein Science; Vol. 21; No. S1; 26th Annual Symposium of the Protein-Society, August 5-8, 2012 , San Diego, CA
Clemons, William; Chartron, Justin et al. (2012) Higher order assemblies in the GET membrane protein targeting pathway FASEB Journal; Vol. 26; 2012 Experimental Biology Meeting, April 21-25, 2012 , San Diego, CA
Chartron, Justin William; Clemons, William M., Jr. (2012) Structural investigations of the Get4/Get5/Sgt2 complex FASEB Journal; Vol. 26; 2012 Experimental Biology Meeting, April 21-25, 2012 , San Diego, CA
Chartron, Justin W.; Clemons, William M., Jr. et al. (2012) The complex process of GETting tail-anchored membrane proteins to the ER Current Opinion in Structural Biology; Vol. 22; No. 2;
Chartron, Justin W.; VanderVelde, David G. et al. (2012) Get5 Carboxyl-terminal Domain Is a Novel Dimerization Motif That Tethers an Extended Get4/Get5 Complex Journal of Biological Chemistry; Vol. 287; No. 11;
Suloway, Christian J. M.; Rome, Michael E. et al. (2012) Tail-anchor targeting by a Get3 tetramer: the structure of an archaeal homologue EMBO Journal; Vol. 31; No. 3;
Chartron, Justin W.; Gonzalez, Grecia M. et al. (2011) A Structural Model of the Sgt2 Protein and Its Interactions with Chaperones and the Get4/Get5 Complex Journal of Biological Chemistry; Vol. 286; No. 39;
Chartron, Justin W.; Suloway, Christian J. M. et al. (2010) Structural characterization of the Get4/Get5 complex and its interaction with Get3 Proceedings of the National Academy of Sciences of the United States of America; Vol. 107; No. 27;
Suloway, Christian J. M.; Chartron, Justin W. et al. (2009) Model for eukaryotic tail-anchored protein binding based on the structure of Get3 Proceedings of the National Academy of Sciences of the United States of America; Vol. 106; No. 35;
Ramasamy, Suresh Kumar; Clemons, William M. (2009) Structure of the twin-arginine signal-binding protein DmsD from Escherichia coli Acta Crystallographica. Section F, Structural Biology and Crystallization Communications; Vol. 65; No. 8;
Ménétret, Jean-François; Schaletzky, Julia et al. (2007) Ribosome Binding of a Single Copy of the SecY Complex: Implications for Protein Translocation Molecular Cell; Vol. 28; No. 6;
Smith, Margaret A.; Clemons, William M., Jr. et al. (2005) Modeling the Effects of prl Mutations on the Escherichia coli SecY Complex Journal of Bacteriology; Vol. 187; No. 18;
Cannon, Kurt S.; Or, Eran et al. (2005) Disulfide bridge formation between SecY and a translocating polypeptide localizes the translocation pore to the center of SecY Journal of Cell Biology; Vol. 169; No. 2;
Clemons, William M., Jr.; Ménétret, Jean-François et al. (2004) Structural insight into the protein translocation channel Current Opinion in Structural Biology; Vol. 14; No. 4;
Osborne, Andrew R.; Clemons, William M., Jr. et al. (2004) A large conformational change of the translocation ATPase SecA Proceedings of the National Academy of Sciences of the United States of America; Vol. 101; No. 30;
van den Berg, Bert; Black, Paul N. et al. (2004) Crystal Structure of the Long-Chain Fatty Acid Transporter FadL Science; Vol. 304; No. 5676;
van den Berg, Bert; Clemons, William M., Jr. et al. (2004) X-ray structure of a protein-conducting channel Nature; Vol. 427; No. 6969;
Brodersen, D. E.; Clemons, W. M., Jr. et al. (2003) Phasing the 30S ribosomal subunit structure Acta Crystallographica Section D: Biological Crystallography; Vol. 59; No. 11;
Brodersen, Ditlev E.; Clemons, William M., Jr. et al. (2002) Crystal structure of the 30 S ribosomal subunit from Thermus thermophilus: structure of the proteins and their interactions with 16 S RNA Journal of Molecular Biology; Vol. 316; No. 3;
Clemons, William M., Jr.; Brodersen, Ditlev E. et al. (2001) Crystal structure of the 30 S ribosomal subunit from Thermus thermophilus: purification, crystallization and structure determination Journal of Molecular Biology; Vol. 310; No. 4;
Ogle, James M.; Brodersen, Ditlev E. et al. (2001) Recognition of Cognate Transfer RNA by the 30S Ribosomal Subunit Science; Vol. 292; No. 5518;
Carter, Andrew P.; Clemons, William M., Jr. et al. (2001) Crystal Structure of an Initiation Factor Bound to the 30S Ribosomal Subunit Science; Vol. 291; No. 5503;
Brodersen, D. E.; Carter, A. P. et al. (2001) Atomic Structures of the 30S Subunit and Its Complexes with Ligands and Antibiotics Cold Spring Harbor Symposia on Quantitative Biology; Vol. 66;
Brodersen, Ditlev E.; Clemons, William M., Jr. et al. (2000) Structural Basis for the Action of the Antibiotics Tetracycline, Pactamycin, and Hygromycin B on the 30S Ribosomal Subunit Cell; Vol. 103; No. 7;
Carter, Andrew P.; Clemons, William M. et al. (2000) Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics Nature; Vol. 407; No. 6802;
Wimberly, Brian T.; Brodersen, Ditlev E. et al. (2000) Structure of the 30S ribosomal subunit Nature; Vol. 407; No. 6802;
Allard, Peter; Rak, Alexey V. et al. (2000) Another piece of the ribosome: solution structure of S16 and its location in the 30S subunit Structure; Vol. 8; No. 8;
Clemons, William M., Jr.; Gowda, Krishne et al. (1999) Crystal structure of the conserved subdomain of human protein SRP54M at 2.1 A resolution: evidence for the mechanism of signal peptide binding Journal of Molecular Biology; Vol. 292; No. 3;
Clemons, William M., Jr.; May, Joanna L. C. et al. (1999) Structure of a bacterial 30S ribosomal subunit at 5.5 Å resolution Nature; Vol. 400; No. 6747;
Gowda, Krishne; Clemons, William M., Jr. et al. (1999) Expression, purification, and crystallography of the conserved methionine-rich domain of human signal recognition particle 54 kda protein Protein Science; Vol. 8; No. 5;
McCutcheon, John P.; Agrawal, Rajendra K. et al. (1999) Location of translational initiation factor IF3 on the small ribosomal subunit Proceedings of the National Academy of Sciences of the United States of America; Vol. 96; No. 8;
Clemons, William M., Jr.; Davies, Christopher et al. (1998) Conformational variability of the N-terminal helix in the structure of ribosomal protein S15 Structure; Vol. 6; No. 4;