Chomyn, Anne

Combined from CaltechAUTHORS

• Hashimoto, Masami and Bacman, Sandra R., el al. (2015) MitoTALENs: A general approach to reduce mutant mtDNA loads and restore oxidative phosphorylation function in mitochondrial diseases; Molecular Therapy; Vol. 23; No. 10; 1592-1599; PMCID PMC4817924; 10.1038/mt.2015.126
• Chen, Ai and Raule, Nicola, el al. (2012) Decreased Reactive Oxygen Species Production in Cells with Mitochondrial Haplogroups Associated with Longevity; PLoS ONE; Vol. 7; No. 10; Art. No. e46473; PMCID PMC3483264; 10.1371/journal.pone.0046473
• Chen, Hsiuchen and Vermulst, Marc, el al. (2010) Mitochondrial Fusion Is Required for mtDNA Stability in Skeletal Muscle and Tolerance of mtDNA Mutations; Cell; Vol. 141; No. 2; 280-289; PMCID PMC2876819; 10.1016/j.cell.2010.02.026
• Hájek, Petr and Chomyn, Anne, el al. (2007) Identification of a Novel Mitochondrial Complex Containing Mitofusin 2 and Stomatin-like Protein 2; Journal of Biological Chemistry; Vol. 282; No. 8; 5670-5681; 10.1074/jbc.M608168200
• Duvezin-Caubet, Stéphane and Jagasia, Ravi, el al. (2006) Proteolytic Processing of OPA1 Links Mitochondrial Dysfunction to Alterations in Mitochondrial Morphology; Journal of Biological Chemistry; Vol. 281; No. 49; 37972-37979; 10.1074/jbc.M606059200
• Chen, Hsiuchen and Chomyn, Anne, el al. (2005) Disruption of fusion results in mitochondrial heterogeneity and dysfunction; Journal of Biological Chemistry; Vol. 280; No. 28; 26185-26192; 10.1074/jbc.M503062200
• Duan, Shili and Hájek, Petr, el al. (2003) Mitochondrial Outer Membrane Permeability Change and Hypersensitivity to Digitonin Early in Staurosporine-induced Apoptosis; Journal of Biological Chemistry; Vol. 278; No. 2; 1346-1353; 10.1074/jbc.M209269200
• Bai, Yidong and Hájek, Petr, el al. (2001) Lack of complex I activity in human cells carrying a mutation in MtDNA-encoded ND4 subunit is corrected by the Saccharomyces cerevisiae NADH-quinone oxidoreductase (NDI1) gene; Journal of Biological Chemistry; Vol. 276; No. 42; 38808-38813
• Chomyn, Anne and Enríquez, José Antonio, el al. (2000) The Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-like Episode Syndrome-associated Human Mitochondrial tRNALeu(UUR) Mutation Causes Aminoacylation Deficiency and Concomitant Reduced Association of mRNA with Ribosomes; Journal of Biological Chemistry; Vol. 275; No. 25; 19198-19209; 10.1074/jbc.M908734199
• Helm, Mark and Florentz, Catherine, el al. (1999) Search for differences in post-transcriptional modification patterns of mitochondrial DNA-encoded wild-type and mutant human tRNALys and tRNALeu(UUR); Nucleic Acids Research; Vol. 27; No. 3; 756-763; 10.1093/nar/27.3.756
• Chomyn, Anne (1998) The Myoclonic Epilepsy and Ragged-Red Fiber Mutation Provides New Insights into Human Mitochondrial Function and Genetics; American Journal of Human Genetics; Vol. 62; No. 4; 745-751; 10.1086/301813
• Zhou, Li and Chomyn, Anne, el al. (1997) Myoclonic Epilepsy and Ragged Red Fibers (MERRF) Syndrome: Selective Vulnerability of CNS Neurons Does Not Correlate with the Level of Mitochondrial tRNA^(lys) Mutation in Individual Neuronal Isolates; Journal of Neuroscience; Vol. 17; No. 20; 7746-7753; PMCID PMC6793887; 10.1523/jneurosci.17-20-07746.1997
• Hofhaus, Götz and Johns, Donald R., el al. (1996) Respiration and Growth Defects in Transmitochondrial Cell Lines Carrying the 11778 Mutation Associated with Leber's Hereditary Optic Neuropathy; Journal of Biological Chemistry; Vol. 271; No. 22; 13155-13161
• Enriquez, José Antonio and Chomyn, Anne, el al. (1995) MtDNA mutation in MERRF syndrome causes defective aminoacylation of tRNA^(Lys) and premature translation termination; Nature Genetics; Vol. 10; No. 1; 47-55; 10.1038/ng0595-47
• Yoneda, Makoto and Chomyn, Anne, el al. (1992) Marked replicative advantage of human mtDNA carrying a point mutation that causes the MELAS encephalomyopathy; Proceedings of the National Academy of Sciences of the United States of America; Vol. 89; No. 23; 11164-11168; PMCID PMC50510; 10.1073/pnas.89.23.11164
• Chomyn, A. and Martinuzzi, A., el al. (1992) MELAS Mutation in mtDNA Binding Site for Transcription Termination Factor Causes Defects in Protein Synthesis and in Respiration but no Change in Levels of Upstream and Downstream Mature Transcripts; Proceedings of the National Academy of Sciences of the United States of America; Vol. 89; No. 10; 4221-4225; PMCID PMC49053; 10.1073/pnas.89.10.4221
• Chomyn, Anne and Meola, Giovanni, el al. (1991) In Vitro Genetic Transfer of Protein Synthesis and Respiration Defects to Mitochondrial DNA-Less Cells with Myopathy-Patient Mitochondria; Molecular and Cellular Biology; Vol. 11; No. 4; 2236-2244; PMCID PMC359920; 10.1128/MCB.11.4.2236
• Chomyn, Anne and Patel, Salil D., el al. (1988) The site of synthesis of the iron-sulfur subunits of the flavoprotein and iron-protein fractions of human NADH dehydrogenase; Journal of Biological Chemistry; Vol. 263; No. 31; 16395-16400
• Chomyn, Anne and Cleeter, Michael W. J., el al. (1986) URF6, last unidentified reading frame of human mtDNA, codes for an NADH dehydrogenase subunit; Science; Vol. 234; No. 4776; 614-618; 10.1126/science.3764430
• Mariottini, Paolo and Chomyn, Anne, el al. (1986) Identification of the polypeptides encoded in the unassigned reading frames 2, 4, 4L, and 5 of human mitochondrial DNA; Proceedings of the National Academy of Sciences of the United States of America; Vol. 83; No. 6; 1563-1567; PMCID PMC323123; 10.1073/pnas.83.6.1563
• Mariottini, Paolo and Chomyn, Anne, el al. (1986) Antibodies against the COOH-terminal undecapeptide of subunit II, but not those against the NH2-terminal decapeptide, immunoprecipitate the whole human cytochrome c oxidase complex; Journal of Biological Chemistry; Vol. 261; No. 7; 3355-3362
• Chomyn, Anne and Mariottini, Paolo, el al. (1983) Identification of the polypeptides encoded in the ATPase 6 gene and in the unassigned reading frames 1 and 3 of human mtDNA; Proceedings of the National Academy of Sciences of the United States of America; Vol. 80; No. 18; 5535-5539; PMCID PMC384292; 10.1073/pnas.80.18.5535
• Chomyn, Anne and Hunkapiller, Michael W., el al. (1981) Alignment of the amino terminal amino acid sequence of human cytochrome c oxidase subunits I and II with the sequence of their putative mRNAs; Nucleic Acids Research; Vol. 9; No. 4; 867-877