[
    {
        "id": "thesis:1189",
        "collection": "thesis",
        "collection_id": "1189",
        "cite_using_url": "https://resolver.caltech.edu/CaltechETD:etd-03282006-131742",
        "primary_object_url": {
            "basename": "Farrar_gl_1961.pdf",
            "content": "final",
            "filesize": 15043025,
            "license": "other",
            "mime_type": "application/pdf",
            "url": "/1189/1/Farrar_gl_1961.pdf",
            "version": "v2.0.0"
        },
        "type": "thesis",
        "title": "Part I. cis- and trans-l,2-Diaminocyclohexanes. Part II. A Study of the Tertiary Amine Precursors of Pirylene",
        "author": [
            {
                "family_name": "Farrar",
                "given_name": "Grover Louis",
                "clpid": "Farrar-Grover-Louis"
            }
        ],
        "thesis_advisor": [
            {
                "family_name": "Buchman",
                "given_name": "Edwin Raphael",
                "clpid": "Buchman-E-R"
            }
        ],
        "thesis_committee": [
            {
                "family_name": "Unknown",
                "given_name": "Unknown"
            }
        ],
        "local_group": [
            {
                "literal": "div_chem"
            }
        ],
        "abstract": "PART I: cis- and trans-1,2-Diaminocyclohexanes:\r\n\r\nWork initiated in these laboratories by Reims and Buchman on the stereospecific conversion of cis- and trans-cyclohexane-1,2-dicarboxylic acids to the corresponding diamines has been extended. cis- and trans-1,2-Diaminocyclohexanes have been characterized by measurements of densities, refractive indices, acid constants and melting points and by preparations of both side-chain and cyclic derivatives.\r\n\r\nPART II: A study of the tertiary amine precursors of pirylene:\r\n\r\nThe observation of Sargent, Buchman and Farquhar, that the Hofmann degradation of N,N-dimethyl-[alpha]-bromomethylpyrrolidinium bromide does not give a single C7H13N amine, but a mixture of isomeric tertiary amines has been confirmed. The components of the C7H13N amine mixture have been identified as follows:\r\n\r\n(1) 1-dimethylamino-4-pentyne\r\n\r\n(2) 1-dimethylamino-2,4-pentadiene\r\n\r\n(3) 1-dimethylamino-3,4-pentadiene\r\n\r\n(4) 1-dimethylamino-3-pentyne\r\n\r\n(5) 1-dimethylamino-1,3-pentadiene.\r\n\r\nComponents (2), (4) and (5) have been isolated and characterized. Components (1) and (3) were detected by infrared spectroscopy.\r\n\r\nA probable course of formation of the C7H13N amine mixture from N,N-dimethyl-[alpha]-bromomethylpyrrolidinium bromide is discussed.",
        "doi": "10.7907/F20M-YA16",
        "publication_date": "1961",
        "thesis_type": "phd",
        "thesis_year": "1961"
    },
    {
        "id": "thesis:4785",
        "collection": "thesis",
        "collection_id": "4785",
        "cite_using_url": "https://resolver.caltech.edu/CaltechETD:etd-12052003-092441",
        "primary_object_url": {
            "basename": "Nevill_wa_1954.pdf",
            "content": "final",
            "filesize": 5752310,
            "license": "other",
            "mime_type": "application/pdf",
            "url": "/4785/1/Nevill_wa_1954.pdf",
            "version": "v2.0.0"
        },
        "type": "thesis",
        "title": "Studies Relating to the Free Radical Chlorination of Cyclobutanecarboxylic Acids",
        "author": [
            {
                "family_name": "Nevill",
                "given_name": "William Albert",
                "clpid": "Nevill-William-Albert"
            }
        ],
        "thesis_advisor": [
            {
                "family_name": "Buchman",
                "given_name": "Edwin Raphael",
                "clpid": "Buchman-E-R"
            }
        ],
        "thesis_committee": [
            {
                "family_name": "Unknown",
                "given_name": "Unknown"
            }
        ],
        "local_group": [
            {
                "literal": "div_chem"
            }
        ],
        "abstract": "The halogenated cyclobutanecarboxylic acid are of importance in connection with projected syntheses of theoretically important cyclobutane derivatives.\r\n\r\nTo facilitate the direct synthesis of such compounds, the free radical chlorination of two simple models, cyclobutanecarboxylic acid and 1,1-cyclobutanedicarboxylic acid, has been investigated.\r\n\r\nNecessary to this study was the synthesis, by means indicative of structure, of 5 isomeric monochlorocyclobutanecarboxylic acids. A chromatographic method has been developed capable of effecting the separation of these isomers from a mixture.\r\n\r\nThe results obtained in this work are consistent with modern interpretations of organic chemistry theory and extend the scope of its application in the field of free radical chlorination to carboxyl-substituted carbocyclic systems.",
        "doi": "10.7907/B3J7-0627",
        "publication_date": "1954",
        "thesis_type": "phd",
        "thesis_year": "1954"
    },
    {
        "id": "thesis:1734",
        "collection": "thesis",
        "collection_id": "1734",
        "cite_using_url": "https://resolver.caltech.edu/CaltechETD:etd-05122003-110549",
        "primary_object_url": {
            "basename": "Phillips_re_1953.pdf",
            "content": "final",
            "filesize": 15059923,
            "license": "other",
            "mime_type": "application/pdf",
            "url": "/1734/1/Phillips_re_1953.pdf",
            "version": "v2.0.0"
        },
        "type": "thesis",
        "title": "Structural Studies on Febrifugine and Isofebrifugine. Alkaloids from Dichroa Febrifuga. Studies on 4-Quinazolones. Synthesis of Some 8-Aminoquinolines",
        "author": [
            {
                "family_name": "Phillips",
                "given_name": "Robert Edward",
                "clpid": "Phillips-Robert-Edward"
            }
        ],
        "thesis_advisor": [
            {
                "family_name": "Koepfli",
                "given_name": "Joseph Blake",
                "clpid": "Koepfli-J-B"
            },
            {
                "family_name": "Buchman",
                "given_name": "Edwin Raphael",
                "clpid": "Buchman-E-R"
            }
        ],
        "thesis_committee": [
            {
                "family_name": "Unknown",
                "given_name": "Unknown"
            }
        ],
        "local_group": [
            {
                "literal": "div_chem"
            }
        ],
        "abstract": "NOTE:  Text or symbols not renderable in plain ASCII are indicated by [...].  Abstract is included in .pdf document.\r\n \r\nStructural studies on two isomeric, antimalarial alkaloids, febrifugine and isofebrifugine, isolated from Dichroa febrifuga, have been continued. The basic structure of both alkaloids is proposed to be 3-[[Beta]-keto ?[gamma]-(3-hydroxy-2-piperidyl)propyl]-4-quinazalone, and the relationship of febrifugine and isofebrifugine to this structure is discussed.\r\n\r\nFebrifugine is shown to be polymorphic, and evidence is presented that the alkaloid [gamma]-dichroine, from Dichroa febrifuga, is not chemically distinct, but a mixture of two of the crystalline modifications of febrifugine.\r\n\r\nThe synthesis of some 3-substituted-4-quinazolones is described. These are shown to be unreactive to benzenesulfonyl chloride, while the parent substance, 4-quinazolone, forms 3-benzenesulfonyl-4-quinazolone. The structure of a hydrolysis product of the letter compound is proposed to be N-(N?-formyl-[?]-aminobenzoyl) benzenesulfonamide, and the synthesis of this and of some related compounds is described.\r\n\r\nThe synthesis of some 8-aminoquinolines related to isoplasmocid was carried out as part of a cooperative project to study to study their action on experimental poliomyelitis in monkeys.  These compounds were tested elsewhere and found to be without specific activity.",
        "doi": "10.7907/QQS1-H154",
        "publication_date": "1953",
        "thesis_type": "phd",
        "thesis_year": "1953"
    },
    {
        "id": "thesis:10510",
        "collection": "thesis",
        "collection_id": "10510",
        "cite_using_url": "https://resolver.caltech.edu/CaltechTHESIS:10122017-111506286",
        "primary_object_url": {
            "basename": "Deutsch_DH_1951.pdf",
            "content": "final",
            "filesize": 19671361,
            "license": "other",
            "mime_type": "application/pdf",
            "url": "/10510/1/Deutsch_DH_1951.pdf",
            "version": "v2.0.0"
        },
        "type": "thesis",
        "title": "I. The Synthesis of Spiro(3,5)Nonane. II. The Presumed Synthesis of 1,3-Cyclobutanedicarboxylic Acid by Markownikoff and Krestownikoff. III. The Synthesis of Cis and Trans-1,3-Cyclobutanedicarboxylic Acids",
        "author": [
            {
                "family_name": "Deutsch",
                "given_name": "Daniel Harold",
                "clpid": "Deutsch-Daniel-Harold"
            }
        ],
        "thesis_advisor": [
            {
                "family_name": "Buchman",
                "given_name": "Edwin Raphael",
                "clpid": "Buchman-E-R"
            }
        ],
        "thesis_committee": [
            {
                "family_name": "Unknown",
                "given_name": "Unknown"
            }
        ],
        "local_group": [
            {
                "literal": "div_chem"
            }
        ],
        "abstract": "<p>Spiro(3,5)nonane was prepared by methods indicative\r\nof structure.</p>\r\n\r\n<p>The historically The historically important acid reported in 1881 by \r\nMarkownikoff and Krestownikoff and assigned the structure \r\n1,3-cyclobutanedicarboxylic acid (a structure which has\r\nnever subsequently been questioned) was shown to be 1-methyl- \r\n1,2-cyclopropanedicarboxylic acid. The mechanism of the for\u00admation \r\nof the Markownikoff-Krestownikoff acid is discussed.</p>\r\n\r\n<p>The previously unknown cis- and trans-1,3-cyclobutane\u00ad-\r\ndicarboxylic acids were synthesized. After numerous unsuc\u00adcessful \r\nattempts the synthesis was achieved starting from \r\npentaerythritol. The reaction between the benzylidene der\u00adivative \r\nof 2,2-bis(bromomethyl)-1,3-propandiol and sodium\r\nmalonic ester gave a condensation product which\tafter hydrolysis\t\r\nand oxidation with nitric acid yielded 1,1,3,3-cyclobutanetetracarboxylic \r\nacid. On decarboxylation of the latter, \r\nthe desired acids were obtained.</p>\r\n",
        "doi": "10.7907/K23E-7793",
        "publication_date": "1951",
        "thesis_type": "phd",
        "thesis_year": "1951"
    },
    {
        "id": "thesis:17484",
        "collection": "thesis",
        "collection_id": "17484",
        "cite_using_url": "https://resolver.caltech.edu/CaltechTHESIS:06252025-005631461",
        "primary_object_url": {
            "basename": "Conly_JC_1950.pdf",
            "content": "final",
            "filesize": 33618100,
            "license": "other",
            "mime_type": "application/pdf",
            "url": "/17484/1/Conly_JC_1950.pdf",
            "version": "v2.0.0"
        },
        "type": "thesis",
        "title": "Spiro(3,3)heptane. The Hunsdiecker Degradation of Carboxylic Acids",
        "author": [
            {
                "family_name": "Conly",
                "given_name": "James Carroll",
                "clpid": "Conly-James-Carroll"
            }
        ],
        "thesis_advisor": [
            {
                "family_name": "Buchman",
                "given_name": "Edwin Raphael",
                "clpid": "Buchman-E-R"
            }
        ],
        "thesis_committee": [
            {
                "family_name": "Unknown",
                "given_name": "Unknown"
            }
        ],
        "local_group": [
            {
                "literal": "div_chem"
            }
        ],
        "abstract": "<p>A general method for the synthesis of polyspiranes containing cyclobutane rings is described. The method involves condensation of sodiomalonic esters with derivatives of trimethylene glycol to give cyclobutane-1,l-dicarboxylates, reduction of these esters with lithium aluminum hydride to the corresponding 1,1-dimethylol cyclobutane, and the use of this substituted trimethylene glycol tor a repetition of the cycle. By means of this series of reactions, spiro-(3,3)-heptane has been made.</p>\r\n<p>The degradation of silver salts of certain types of aliphatic oarboxylle acids with bromine has been investigated. Halogen-substituted acids were found to give results that were dependent upon the position of the halogen and the technique that was employed. Polycarboxylic acids, contrary to some previous reports, were found to undergo the reaction in fair yields, giving alkyl polybromides. The cyclobutane ring was found to be cleaved during the degradation if carried out as customarily described, but use of low temperature techniques gave cyclobutyl bromides in good yields. The mechanism of the reaction is the subject of some speculation, but its synthetic usefulness seems considerable.</p>",
        "doi": "10.7907/yc45-qe31",
        "publication_date": "1950",
        "thesis_type": "phd",
        "thesis_year": "1950"
    },
    {
        "id": "thesis:619",
        "collection": "thesis",
        "collection_id": "619",
        "cite_using_url": "https://resolver.caltech.edu/CaltechETD:etd-02122009-093328",
        "primary_object_url": {
            "basename": "Monroe_ep_1949.pdf",
            "content": "final",
            "filesize": 1959925,
            "license": "other",
            "mime_type": "application/pdf",
            "url": "/619/1/Monroe_ep_1949.pdf",
            "version": "v2.0.0"
        },
        "type": "thesis",
        "title": "I. Derivatives of Spiro (3,3) Heptanetetra Carboxylic Acid. II. Attempted New Synthesis of Cis-2 Butene-1, 4-Diol",
        "author": [
            {
                "family_name": "Monroe",
                "given_name": "Emmett Paul",
                "clpid": "Monroe-Emmett-Paul"
            }
        ],
        "thesis_advisor": [
            {
                "family_name": "Buchman",
                "given_name": "Edwin Raphael",
                "clpid": "Buchman-E-R"
            }
        ],
        "thesis_committee": [
            {
                "family_name": "Unknown",
                "given_name": "Unknown"
            }
        ],
        "local_group": [
            {
                "literal": "div_chem"
            }
        ],
        "abstract": "I. DERIVATIVES OF SPIRO(3,3) HEPTANETETRACARBOXYLIC ACID:\r\n\r\nThe isolation of the isoamyl ester of spiroheptanetetra-carboxylic acid, prepared by the condensation of sodiomalonic ester with pentaerythrityl tetrabromide in isoamyl alcohol is reported. The synthetic method is that of Fecht as modified by Backer and Schurink. Pentaerythrityl benzenesulfonate is substituted for the bromide in the reaction with the malonic ester, but the yield is found to be much poorer. Attempts to prepare the ethyl ester of spiroheptanetetracarboxylic acid by using pentaerythrityl benzenesulfonate in ethyl alcohol solvent, and pentaerythrityl bromide in excess malonate and xylene solvents are described. These experiments did not produce a practical synthesis of the ethyl ester.\r\n\r\nThe unsuccessful attempt to reduce the isoamyl ester of spiroheptanetetracarboxylic acid with lithium aluminum hydride is described.\r\n\r\nII. ATTEMPTED NEW SYNTHESIS OF CIS-2-BUTENE-,4-DIOL:\r\n\r\nA synthesis of cis-2-butene-1,4-diol by the reduction of maleic anhydride with lithium aluminum hydride is attempted. Two experiments are described, one of which employs an aqueous system in the isolation of the product, the other a non-aqueous system. No amount of any consequence of the diol was obtained. A discussion of lithium aluminum hydride as a reducing agent is included.\r\n",
        "doi": "10.7907/VB67-1R54",
        "publication_date": "1949",
        "thesis_type": "masters",
        "thesis_year": "1949"
    },
    {
        "id": "thesis:3941",
        "collection": "thesis",
        "collection_id": "3941",
        "cite_using_url": "https://resolver.caltech.edu/CaltechETD:etd-10062005-083407",
        "primary_object_url": {
            "basename": "Winniford_rs_1948.pdf",
            "content": "final",
            "filesize": 2734407,
            "license": "other",
            "mime_type": "application/pdf",
            "url": "/3941/1/Winniford_rs_1948.pdf",
            "version": "v2.0.0"
        },
        "type": "thesis",
        "title": "I. The Synthesis of Methylenecyclobutane from Pentaerythrityl Chloride. II. The Attempted Synthesis of Cyclobutane. III. A Reinvestigation of the Synthesis of Spiroheptanedicarboxylic Acid",
        "author": [
            {
                "family_name": "Winniford",
                "given_name": "Robert Stanley",
                "clpid": "Winniford-Robert-Stanley"
            }
        ],
        "thesis_advisor": [
            {
                "family_name": "Buchman",
                "given_name": "Edwin Raphael",
                "clpid": "Buchman-E-R"
            }
        ],
        "thesis_committee": [
            {
                "family_name": "Unknown",
                "given_name": "Unknown"
            }
        ],
        "local_group": [
            {
                "literal": "div_chem"
            }
        ],
        "abstract": "I. The Synthesis of Methylenecyclobutane from Pentaerythrityl Chloride\r\n\r\nA new method for preparing methylenecyclobutane is described in which the starting material is pentaerythrityl tetrachloride. Pentaerythrityl chloride is dechlorinated by zinc dust in the presence of sodium iodide and sodium carbonate, using as solvent either diethylene glycol or acetamide. Reasonable yields are obtained.\r\n\r\nII. The Attempted Synthesis of Cyclobutane\r\n\r\nA synthesis of cyclobutanone through treatment of the methylenecyclobutane-nitrogen trioxide addition compound, with alcoholic potassium hydroxide is not successful.\r\n\r\nThe oxidation of methylenecyclobutane dibromide with potassium permanganate does not yield cyclobutanone.\r\n\r\nIII. A Reinvestigation of the Synthesis of Spiroheptanedicarboxylic Acid\r\n\r\nAn experiment is described in which two mols of malonic ester are condensed with one mol of pentaerythrityl chloride to form spiroheptanetetracarboxylic acid ester. The tetra acid is decarboxylated by heat to afford the dicarboxylic acid. The procedure is a modification of that described in the literature, whereby spiroheptanedicarboxylic acid is prepared from pentaerythrityl bromide.\r\n\r\nA parallel experiment in which pentaerythrityl bromide is condensed with malonic ester is also described.\r\n\r\nThe yields are low in each case.",
        "doi": "10.7907/ZMYX-Z369",
        "publication_date": "1948",
        "thesis_type": "masters",
        "thesis_year": "1948"
    },
    {
        "id": "thesis:17437",
        "collection": "thesis",
        "collection_id": "17437",
        "cite_using_url": "https://resolver.caltech.edu/CaltechTHESIS:06092025-221024740",
        "primary_object_url": {
            "basename": "Howton_DR_1946.pdf",
            "content": "final",
            "filesize": 49714893,
            "license": "other",
            "mime_type": "application/pdf",
            "url": "/17437/1/Howton_DR_1946.pdf",
            "version": "v2.0.0"
        },
        "type": "thesis",
        "title": "The Synthesis of Potential Antimalarials. I. 1,3-Dimethylpiperidone-4. II. Application of the Darzens-Claisen Reaction to a \u03b2-Dialkylaminoketone. III. 6'-Methoxyrubanol-9. IV. Synthesis of Some 2-Phenylquinolyl-4-\u03b1-Piperidylcarbinols. V. 2,6-Diphenylpyridyl-4-di-n-butylaminomethylcarbinol. VI. Preparation and Reduction of 9-Picolinylanthracene. VII. Preparation and Reduction of \u03b1-Phenacylpyridine. A New Guinea-Pig Test for Relaxin Activity.",
        "author": [
            {
                "family_name": "Howton",
                "given_name": "David Ronald",
                "clpid": "Howton-David-Ronald"
            }
        ],
        "thesis_advisor": [
            {
                "family_name": "Buchman",
                "given_name": "Edwin Raphael",
                "clpid": "Buchman-E-R"
            }
        ],
        "thesis_committee": [
            {
                "family_name": "Unknown",
                "given_name": "Unknown"
            }
        ],
        "local_group": [
            {
                "literal": "div_chem"
            }
        ],
        "abstract": "No abstract.",
        "doi": "10.7907/y07y-vt13",
        "publication_date": "1946",
        "thesis_type": "phd",
        "thesis_year": "1946"
    },
    {
        "id": "thesis:17160",
        "collection": "thesis",
        "collection_id": "17160",
        "cite_using_url": "https://resolver.caltech.edu/CaltechTHESIS:04162025-230307879",
        "primary_object_url": {
            "basename": "Seneker_JA_1945.pdf",
            "content": "final",
            "filesize": 11068522,
            "license": "other",
            "mime_type": "application/pdf",
            "url": "/17160/1/Seneker_JA_1945.pdf",
            "version": "v2.0.0"
        },
        "type": "thesis",
        "title": "The Preparation of Cinchoninic Acids and Related Compounds",
        "author": [
            {
                "family_name": "Seneker",
                "given_name": "James Albert",
                "clpid": "Seneker-James-Albert"
            }
        ],
        "thesis_advisor": [
            {
                "family_name": "Buchman",
                "given_name": "Edwin Raphael",
                "clpid": "Buchman-E-R"
            }
        ],
        "thesis_committee": [
            {
                "family_name": "Unknown",
                "given_name": "Unknown"
            }
        ],
        "local_group": [
            {
                "literal": "div_chem"
            }
        ],
        "abstract": "No abstract.",
        "doi": "10.7907/bb4y-j481",
        "publication_date": "1945",
        "thesis_type": "masters",
        "thesis_year": "1945"
    },
    {
        "id": "thesis:17180",
        "collection": "thesis",
        "collection_id": "17180",
        "cite_using_url": "https://resolver.caltech.edu/CaltechTHESIS:04282025-201213151",
        "primary_object_url": {
            "basename": "Keilin_B_1945.pdf",
            "content": "final",
            "filesize": 16929823,
            "license": "other",
            "mime_type": "application/pdf",
            "url": "/17180/1/Keilin_B_1945.pdf",
            "version": "v2.0.0"
        },
        "type": "thesis",
        "title": "I. The Attempted Synthesis of Cyclobutane from Tetramethylene Dibromide. II. Attempted New Syntheses of 1,3 Cyclobutane Dicarboxylic Acid. III. The Synthesis of Ortho and Meta Arsanilic Acid",
        "author": [
            {
                "family_name": "Keilin",
                "given_name": "Bertram",
                "clpid": "Keilin-Bertram"
            }
        ],
        "thesis_advisor": [
            {
                "family_name": "Buchman",
                "given_name": "Edwin Raphael",
                "clpid": "Buchman-E-R"
            },
            {
                "family_name": "Pressman",
                "given_name": "David",
                "clpid": "Pressman-David"
            }
        ],
        "thesis_committee": [
            {
                "family_name": "Unknown",
                "given_name": "Unknown"
            }
        ],
        "local_group": [
            {
                "literal": "div_chem"
            }
        ],
        "abstract": "No abstract.",
        "doi": "10.7907/ehs6-rt06",
        "publication_date": "1945",
        "thesis_type": "masters",
        "thesis_year": "1945"
    },
    {
        "id": "thesis:17151",
        "collection": "thesis",
        "collection_id": "17151",
        "cite_using_url": "https://resolver.caltech.edu/CaltechTHESIS:04122025-010458038",
        "primary_object_url": {
            "basename": "Sargent_H_1944.pdf",
            "content": "archival",
            "filesize": 27739406,
            "license": "other",
            "mime_type": "application/pdf",
            "url": "/17151/1/Sargent_H_1944.pdf",
            "version": "v2.0.0"
        },
        "type": "thesis",
        "title": "I. The Constitution of Naphthenic Acids. II. Heterocyclic Nitrogen and Sulfur Studies. III. The Structure of Pirylene",
        "author": [
            {
                "family_name": "Sargent",
                "given_name": "Herbert",
                "clpid": "Sargent-Herbert"
            }
        ],
        "thesis_advisor": [
            {
                "family_name": "Buchman",
                "given_name": "Edwin Raphael",
                "clpid": "Buchman-E-R"
            }
        ],
        "thesis_committee": [
            {
                "family_name": "Unknown",
                "given_name": "Unknown"
            }
        ],
        "local_group": [
            {
                "literal": "div_chem"
            }
        ],
        "abstract": "<p>The preparation of 4-methyl-5-(hydroxymethyl)-thiazole by several different methods has been investigated. It may conveniently be obtained by a two-step synthesis starting from chloroacetone.</p>\r\n<p>The thiamin analog was prepared from 4-methyl-5 (hydroxymethyl)-thiazole and found to be completely devoid of vitamin activity when tested with Phycomyces Blakesleeanus and with rats.</p>\r\n<p>The effects of acetyl choline, histamine, atropine and adrenaline on the long muscles of the Sea Cucumber and on lobster intestine were investigated.</p>\r\n<p>Lobsters can be passively and actively sensitized to ovalbumen and upon anaphylaxis a substance is given off into their blood stream that causes guinea pig small intestine to contract. This substance could very well be histamine.</p>",
        "doi": "10.7907/b94m-8w06",
        "publication_date": "1944",
        "thesis_type": "phd",
        "thesis_year": "1944"
    },
    {
        "id": "thesis:17106",
        "collection": "thesis",
        "collection_id": "17106",
        "cite_using_url": "https://resolver.caltech.edu/CaltechTHESIS:03282025-213401864",
        "primary_object_url": {
            "basename": "Golding_DRV_1944.pdf",
            "content": "final",
            "filesize": 18483166,
            "license": "other",
            "mime_type": "application/pdf",
            "url": "/17106/1/Golding_DRV_1944.pdf",
            "version": "v2.0.0"
        },
        "type": "thesis",
        "title": "I. The Heat Capacity, Heats of Transition, Fusion and Vaporization, Vapor Pressure and Entropy of 1, 1, 1, Trifluoroethane. II. Synthesis of Potential Antimalarials and Related Compounds",
        "author": [
            {
                "family_name": "Golding",
                "given_name": "David Roy Vincent",
                "clpid": "Golding-David-Roy-Vincent"
            }
        ],
        "thesis_advisor": [
            {
                "family_name": "Buchman",
                "given_name": "Edwin Raphael",
                "clpid": "Buchman-E-R"
            },
            {
                "family_name": "Yost",
                "given_name": "Don M.",
                "clpid": "Yost-D-M"
            }
        ],
        "thesis_committee": [
            {
                "family_name": "Unknown",
                "given_name": "Unknown"
            }
        ],
        "local_group": [
            {
                "literal": "div_chem"
            }
        ],
        "abstract": "Part of the low temperature calorimetric research program\r\nof this laboratory has been the careful detennination of the\r\nentropy of simple compounds in which hindered rotation about\r\nsingle bonds would be expected and for which straightforward\r\nand reliable statistical mechanical calculations can be made. Of the compounds available, ethane and similar molecules with two symmetrical groups on a common axis seem best suited for study both because of their convenient boiling points and because their configurations and normal frequencies can be readily determined. The existence of a barrier of about 3000 cal/mole hindering internal rotation in ethane was established by Kemp and Pitzer and Kistiakowsky, Lacher and Stitt.",
        "doi": "10.7907/he2n-hb33",
        "publication_date": "1944",
        "thesis_type": "phd",
        "thesis_year": "1944"
    },
    {
        "id": "thesis:10038",
        "collection": "thesis",
        "collection_id": "10038",
        "cite_using_url": "https://resolver.caltech.edu/CaltechTHESIS:02012017-104146897",
        "primary_object_url": {
            "basename": "McNeely_wh_1943.pdf",
            "content": "final",
            "filesize": 24206826,
            "license": "other",
            "mime_type": "application/pdf",
            "url": "/10038/1/McNeely_wh_1943.pdf",
            "version": "v2.0.0"
        },
        "type": "thesis",
        "title": "I. Contribution to the Stereochemistry of Stilbenes by Application of Chromatographic Methods. II. Separation of Some Cis- and Trans-Oximes by Means of the Chromatographic Brush Method. III. Chromatographic Isolation of Homopterocarpin and Vanillin from Red Sandalwood. IV. Model Experiments Directed Toward the Synthesis of Quinine",
        "author": [
            {
                "family_name": "McNeely",
                "given_name": "William Harold",
                "clpid": "McNeely-William-Harold"
            }
        ],
        "thesis_advisor": [
            {
                "family_name": "Zechmeister",
                "given_name": "Laszlo",
                "clpid": "Zechmeister-L"
            },
            {
                "family_name": "Buchman",
                "given_name": "Edwin Raphael",
                "clpid": "Buchman-E-R"
            }
        ],
        "thesis_committee": [
            {
                "family_name": "Unknown",
                "given_name": "Unknown"
            }
        ],
        "local_group": [
            {
                "literal": "div_chem"
            }
        ],
        "abstract": "<p>Part I.</p>\r\n\r\n<p>The chromatographic brush method, with permanganate as brush reagent, \r\nhas been used for the detection, separation and estimation of the\r\ncis- and trans-forms of stilbene, p-methylstilbene and p-methoxystilbene.\r\nIn a mixture composed of two stereoisomeric compounds, 1-2% of either form\r\ncan be detected. The method can be used for the study of the interconversion\r\nof stilbene cis- and trans-isomers. Fluorescent contaminants can\r\nbe removed by chromatography in ultraviolet light.</p>\r\n\r\n<p>Part II.</p>\r\n\r\n<p>The chromatographic brush method, with an ammoniacal copper solution\r\nas color reagent, has been used for the detection and separation of\r\ncis- and trans-benzoin and anisoin oximes on Neutrol Filtrol columns.\r\nIn a mixture composed of two stereoisoraers, 1-2% of either form can be\r\nrapidly detected in the presence of the other. Some data concerning the\r\ninterconversion of stereoisomeric oximes is given, and the influence of\r\nthe adsorbent on the cis-trans shift is discussed.</p>\r\n\r\n<p>Part III.</p>\r\n\r\n<p>A preliminary chromatographic investigation of some colorless\r\nconstituents of red sandalwood has been carried out. The chromatographic\r\nisolation and purification of homopterocarpin and vanillin \r\nis described</p>\r\n\r\n<p>Part IV.</p>\r\n\r\n<p>Model experiments directed towards the synthesis of quinine\r\nhave been carried out.</p>",
        "doi": "10.7907/R6H2-GN02",
        "publication_date": "1943",
        "thesis_type": "phd",
        "thesis_year": "1943"
    },
    {
        "id": "thesis:17036",
        "collection": "thesis",
        "collection_id": "17036",
        "cite_using_url": "https://resolver.caltech.edu/CaltechTHESIS:02282025-211013383",
        "primary_object_url": {
            "basename": "Schlatter_MJ_1941.pdf",
            "content": "final",
            "filesize": 18494721,
            "license": "other",
            "mime_type": "application/pdf",
            "url": "/17036/1/Schlatter_MJ_1941.pdf",
            "version": "v2.0.0"
        },
        "type": "thesis",
        "title": "I. The Isomeric 2,3-Epoxypentanes and 2-Pentanes. The Extent to Which Mixtures of Diastereomers are Formed in Reactions of Some Pentane Compounds. II. The Preparation of Cyclopropane. III. The Thermal Decomposition of Trans-1,2-Cyclobutane-Bis(Trimethylammonium) Hydroxide",
        "author": [
            {
                "family_name": "Schlatter",
                "given_name": "Maurice Jay",
                "clpid": "Schlatter-Maurice-Jay"
            }
        ],
        "thesis_advisor": [
            {
                "family_name": "Buchman",
                "given_name": "Edwin Raphael",
                "clpid": "Buchman-E-R"
            }
        ],
        "thesis_committee": [
            {
                "family_name": "Unknown",
                "given_name": "Unknown"
            }
        ],
        "local_group": [
            {
                "literal": "div_chem"
            }
        ],
        "abstract": "No abstract.",
        "doi": "10.7907/9txa-0p49",
        "publication_date": "1941",
        "thesis_type": "phd",
        "thesis_year": "1941"
    },
    {
        "id": "thesis:16991",
        "collection": "thesis",
        "collection_id": "16991",
        "cite_using_url": "https://resolver.caltech.edu/CaltechTHESIS:02102025-210337743",
        "primary_object_url": {
            "basename": "Fischer_JR_1941.pdf",
            "content": "final",
            "filesize": 19214080,
            "license": "other",
            "mime_type": "application/pdf",
            "url": "/16991/1/Fischer_JR_1941.pdf",
            "version": "v2.0.0"
        },
        "type": "thesis",
        "title": "The Preparation of Methylene Cyclobutane and Methyl \u0394' Cyclobutane",
        "author": [
            {
                "family_name": "Fischer",
                "given_name": "James Rodney",
                "clpid": "Fischer-James-Rodney"
            }
        ],
        "thesis_advisor": [
            {
                "family_name": "Buchman",
                "given_name": "Edwin Raphael",
                "clpid": "Buchman-E-R"
            }
        ],
        "thesis_committee": [
            {
                "family_name": "Unknown",
                "given_name": "Unknown"
            }
        ],
        "local_group": [
            {
                "literal": "div_chem"
            }
        ],
        "abstract": "No abstract.",
        "doi": "10.7907/mdp4-fq82",
        "publication_date": "1941",
        "thesis_type": "masters",
        "thesis_year": "1941"
    },
    {
        "id": "thesis:16989",
        "collection": "thesis",
        "collection_id": "16989",
        "cite_using_url": "https://resolver.caltech.edu/CaltechTHESIS:02102025-185855030",
        "primary_object_url": {
            "basename": "Farquhar_JP_1941.pdf",
            "content": "final",
            "filesize": 7193283,
            "license": "other",
            "mime_type": "application/pdf",
            "url": "/16989/1/Farquhar_JP_1941.pdf",
            "version": "v2.0.0"
        },
        "type": "thesis",
        "title": "An Investigation of the Synthesis of \"Pirylene\"",
        "author": [
            {
                "family_name": "Farquhar",
                "given_name": "John Percival",
                "clpid": "Farquhar-John-Percival"
            }
        ],
        "thesis_advisor": [
            {
                "family_name": "Buchman",
                "given_name": "Edwin Raphael",
                "clpid": "Buchman-E-R"
            }
        ],
        "thesis_committee": [
            {
                "family_name": "Unknown",
                "given_name": "Unknown"
            }
        ],
        "local_group": [
            {
                "literal": "div_chem"
            }
        ],
        "abstract": "No abstract.",
        "doi": "10.7907/zgmr-qz28",
        "publication_date": "1941",
        "thesis_type": "masters",
        "thesis_year": "1941"
    }
]