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@article{https://resolver.caltech.edu/CaltechAUTHORS:20200421-095315855,
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20200330-105819372,
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    title = "Enantioselective C-H amination via directed evolution of cytochrome P450 enzymes",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20200121-114421759,
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    journal = "Nature Catalysis",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20190912-124018949,
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20191125-092520827,
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    journal = "Journal of the American Chemical Society",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20191022-085105295,
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    title = "Nitrene Transfer Catalyzed by a Non-Heme Iron Enzyme and Enhanced by Non-Native Small-Molecule Cofactors",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20190304-085432637,
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20191014-083130371,
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20190821-144026374,
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20190903-130240854,
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20190807-153750847,
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20190715-092459913,
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20190607-130827085,
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20190509-152409265,
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20190415-082330973,
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20181029-094838266,
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@other{https://resolver.caltech.edu/CaltechAUTHORS:20190823-075522116,
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20190102-135256908,
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20190122-134051110,
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20181023-102546587,
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20190213-135152848,
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20181030-105013022,
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20180723-085717756,
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    title = "A General Tool for Engineering the NAD/NADP Cofactor Preference of Oxidoreductases",
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    title = "Directed evolution of cytochrome c for carbon–silicon bond formation: Bringing silicon to life",
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    title = "Highly Stereoselective Biocatalytic Synthesis of Key Cyclopropane Intermediate to Ticagrelor",
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    title = "Identification of Mechanism-Based Inactivation in P450-Catalyzed Cyclopropanation Facilitates Engineering of Improved Enzymes",
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    title = "A Panel of TrpB Biocatalysts Derived from Tryptophan Synthase through the Transfer of Mutations that Mimic Allosteric Activation",
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    title = "Enhancement of cellulosome-mediated deconstruction of cellulose by improving enzyme thermostability",
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    title = "Synthesis of β-Branched Tryptophan Analogues Using an Engineered Subunit of Tryptophan Synthase",
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    title = "Artificial domain duplication replicates evolutionary history of ketol-acid reductoisomerases",
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    title = "Discovery of a regioselectivity switch in nitrating P450s guided by molecular dynamics simulations and Markov models",
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    doi = "10.1038/NCHEM.2474",
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    title = "Asymmetric Enzymatic Synthesis of Allylic Amines: A Sigmatropic Rearrangement Strategy",
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    doi = "10.1002/anie.201601056",
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    title = "Exploring the Mechanism Responsible for Cellulase Thermostability by Structure-Guided Recombination",
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    doi = "10.1371/journal.pone.0147485",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20160603-153016574,
    title = "Rhodopsin Engineering through Structure-Guided Recombination",
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    title = "Mutations in adenine-binding pockets enhance catalytic properties of NAD(P)H-dependent enzymes",
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    doi = "10.1093/protein/gzv057",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20151112-080107171,
    title = "Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20151105-083025660,
    title = "Chemomimetic Biocatalysis: Exploiting the Synthetic Potential of Cofactor-Dependent Enzymes To Create New Catalysts",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20150928-085007684,
    title = "Structural Adaptability Facilitates Histidine Heme Ligation in a Cytochrome P450",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20151109-085022815,
    title = "The nature of chemical innovation: new enzymes by evolution",
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    issn = "0033-5835",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20150728-090618874,
    title = "Genetically Encoded Spy Peptide Fusion System to Detect Plasma Membrane-Localized Proteins In Vivo",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20150612-152121122,
    title = "Recent advances in engineering microbial rhodopsins for optogenetics",
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    title = "Cofactor specificity motifs and the induced fit mechanism in class I ketol-acid reductoisomerases",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20150504-091714076,
    title = "Enantioselective Enzyme-Catalyzed Aziridination Enabled by Active-Site Evolution of a Cytochrome P450",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20150209-090308645,
    title = "Expanding the Enzyme Universe: Accessing Non-Natural Reactions by Mechanism-Guided Directed Evolution",
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    doi = "10.1002/anie.201409470",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20140707-083154824,
    title = "Directed Evolution of Gloeobacter violaceus Rhodopsin Spectral Properties",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20141015-151531581,
    title = "Non-natural Olefin Cyclopropanation Catalyzed by Diverse Cytochrome P450s and Other Hemoproteins",
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    title = "Cellular synthesis of non-linear proteins",
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    title = "Enantioselective Intramolecular C-H Amination Catalyzed by Engineered Cytochrome P450 Enzymes In Vitro and In Vivo",
    journal = "Angewandte Chemie International Edition",
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    doi = "10.1002/anie.201304401",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20130819-153647713,
    title = "Role of cysteine residues in thermal inactivation of fungal Cel6A cellobiohydrolases",
    journal = "Biochimica et Biophysica Acta - Proteins and Proteomics",
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    title = "A serine-substituted P450 catalyzes highly efficient carbene transfer to olefins in vivo",
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    doi = "10.1038/nchembio.1278",
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    title = "General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADH",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20130703-095728488,
    title = "Engineered thermostable fungal Cel6A and Cel7A cellobiohydrolases hydrolyze cellulose efficiently at elevated temperatures",
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    title = "High-Throughput Screening for Terpene-Synthase-Cyclization Activity and Directed Evolution of a Terpene Synthase",
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    doi = "10.1002/anie.201301362",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20130226-103727663,
    title = "Chimeragenesis of distantly-related proteins by noncontiguous recombination",
    journal = "Protein Science",
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    title = "Olefin Cyclopropanation via Carbene Transfer Catalyzed by Engineered Cytochrome P450 Enzymes",
    journal = "Science",
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    url = "https://resolver.caltech.edu/CaltechAUTHORS:20130208-132114060",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20130225-163008905,
    title = "Navigating the protein fitness landscape with Gaussian processes",
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    url = "https://resolver.caltech.edu/CaltechAUTHORS:20130225-163008905",
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    title = "Methods in Protein Design",
    chapter = "Efficient Sampling of SCHEMA Chimera Families to Identify Useful Sequence Elements",
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    url = "https://resolver.caltech.edu/CaltechAUTHORS:20130620-125417347",
    id = "record",
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    title = "Chemical Neurobiology : Methods and Protocols",
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    url = "https://resolver.caltech.edu/CaltechAUTHORS:20130410-132453635",
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    isbn = "978-1-62703-344-2",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20130611-082534229,
    title = "Structure-guided engineering of Lactococcus lactis alcohol dehydrogenase LlAdhA for improved conversion of isobutyraldehyde to isobutanol",
    journal = "Journal of Biotechnology",
    year = "2012",
    url = "https://resolver.caltech.edu/CaltechAUTHORS:20130611-082534229",
    id = "record",
    issn = "0168-1656",
    doi = "10.1016/j.jbiotec.2012.08.008",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20130114-102154716,
    title = "A diverse set of family 48 bacterial glycoside hydrolase cellulases created by structure-guided recombination",
    journal = "FEBS Journal",
    year = "2012",
    url = "https://resolver.caltech.edu/CaltechAUTHORS:20130114-102154716",
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    doi = "10.1111/febs.12032",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20130107-104235257,
    title = "Highly thermostable fungal cellobiohydrolase I (Cel7A) engineered using predictive methods",
    journal = "Protein Engineering, Design and Selection",
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    url = "https://resolver.caltech.edu/CaltechAUTHORS:20130107-104235257",
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    doi = "10.1093/protein/gzs058",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20130220-094932746,
    title = "Random Field Model Reveals Structure of the Protein Recombinational Landscape",
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    doi = "10.1371/journal.pcbi.1002713",
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    title = "Structure-Guided Directed Evolution of Highly Selective P450-Based Magnetic Resonance Imaging Sensors for Dopamine and Serotonin",
    journal = "Journal of Molecular Biology",
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    url = "https://resolver.caltech.edu/CaltechAUTHORS:20121030-144039360",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20120828-070344527,
    title = "High Resolution Models from Low Resolution Data: Recombination of Fragments for Crystallographic Structure Determination",
    journal = "Protein Science",
    year = "2012",
    url = "https://resolver.caltech.edu/CaltechAUTHORS:20120828-070344527",
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    volume = "21"
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20120824-161422230,
    title = "Computational Thermostable Cellulase Engineering for Enhanced Biofuel Production",
    journal = "Protein Science",
    year = "2012",
    url = "https://resolver.caltech.edu/CaltechAUTHORS:20120824-161422230",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20120827-083652928,
    title = "Metalloprotein-based contrast sensors for neurochemical detection by MRI",
    journal = "Protein Science",
    year = "2012",
    url = "https://resolver.caltech.edu/CaltechAUTHORS:20120827-083652928",
    id = "record",
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    title = "SCHEMA-Designed Variants of Human Arginase I and II Reveal Sequence Elements Important to Stability and Catalysis",
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    year = "2012",
    url = "https://resolver.caltech.edu/CaltechAUTHORS:20120716-102139957",
    id = "record",
    issn = "2161-5063",
    doi = "10.1021/sb300014t",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20120420-110357141,
    title = "Comparison of random mutagenesis and semi-rational designed libraries for improved cytochrome P450 BM3-catalyzed hydroxylation of small alkanes",
    journal = "Protein Engineering, Design and Selection",
    year = "2012",
    url = "https://resolver.caltech.edu/CaltechAUTHORS:20120420-110357141",
    id = "record",
    issn = "1741-0126",
    doi = "10.1093/protein/gzs004",
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    title = "Utilizing Terminal Oxidants to Achieve P450-Catalyzed Oxidation of Methane",
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    url = "https://resolver.caltech.edu/CaltechAUTHORS:20120522-134624475",
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    doi = "10.1002/adsc.201100833",
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    title = "Microbial Metabolic Engineering",
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    id = "record",
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    title = "Cytochrome P450: taming a wild type enzyme",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20111111-135716977,
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20180821-075520096,
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    title = "Engineered Bacterial Mimics of Human Drug Metabolizing Enzyme CYP2C9",
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    title = "Engineered ketol-acid reductoisomerase and alcohol dehydrogenase enable anaerobic 2-methylpropan-1-ol production at theoretical yield in Escherichia coli",
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    title = "Improved Product-Per-Glucose Yields in P450-Dependent Propane Biotransformations Using Engineered Escherichia coli",
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    title = "Self-Organization, Layered Structure, and Aggregation Enhance Persistence of a Synthetic Biofilm Consortium",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20110322-095840300,
    title = "Metal-Substituted Protein MRI Contrast Agents Engineered for Enhanced Relaxivity and Ligand Sensitivity",
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    title = "Comparison of Family 9 Cellulases from Mesophilic and Thermophilic Bacteria",
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    doi = "10.1128/AEM.01802-10",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20110414-084904112,
    title = "Enzymatic functionalization of carbon-hydrogen bonds",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20110118-104553247,
    title = "Combinatorial Alanine Substitution Enables Rapid Optimization of Cytochrome P450\_(BM3) for Selective Hydroxylation of Large Substrates",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20101108-110520683,
    title = "Efficient screening of fungal cellobiohydrolase class I enzymes for thermostabilizing sequence blocks by SCHEMA structure-guided recombination",
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    doi = "10.1093/protein/gzq063",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20180820-160726572,
    title = "Combinatorial Recombination of Gene Fragments to Construct a Library of Chimeras",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20101011-132711462,
    title = "A General Mechanism for Network-Dosage Compensation in Gene Circuits",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20100713-090942319,
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    title = "Directed evolution of a magnetic resonance imaging contrast agent for noninvasive imaging of dopamine",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20090910-084155263,
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    journal = "Journal of Bacteriology",
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    id = "record",
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    title = "Laboratory evolution of cytochrome P450 BM-3 monooxygenase for organic cosolvents",
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    title = "Directed Evolution Library Creation: Methods and Protocols",
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    title = "Regio- and Enantioselective Alkane Hydroxylation with Engineered Cytochromes P450 BM-3",
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    title = "Global incorporation of norleucine in place of methionine in cytochrome P450 BM-3 heme domain increases peroxygenase activity",
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    title = "Thermostabilization of a Cytochrome P450 Peroxygenase",
    journal = "ChemBioChem",
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    title = "Method to protect a targeted amino acid residue during random mutagenesis",
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    title = "Engineering proteins that bind, move, make and break DNA",
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    title = "Library analysis of SCHEMA-guided protein recombination",
    journal = "Protein Science",
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    title = "A Self-Sufficient Peroxide-Driven Hydroxylation Biocatalyst",
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    id = "record",
    issn = "1433-7851",
    doi = "10.1002/anie.200351434",
    volume = "42"
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    title = "General Method for Sequence-independent Site-directed Chimeragenesis",
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    title = "A C35 Carotenoid Biosynthetic Pathway",
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    title = "Protein Dynamics in a Family of Laboratory Evolved Thermophilic Enzymes",
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    title = "Functional Expression of a Fungal Laccase in Saccharomyces cerevisiae by Directed Evolution",
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    title = "Colorimetric Assays for Biodegradation of Polycyclic Aromatic Hydrocarbons by Fungal Laccases",
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    title = "Evolution of the C30 Carotenoid Synthase CrtM for Function in a C40 Pathway",
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    title = "Laboratory evolution of a soluble, self-sufficient, highly active alkane hydroxylase",
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    title = "Regioselectivity and Activity of Cytochrome P450 BM-3 and Mutant F87A in Reactions Driven by Hydrogen Peroxide",
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    title = "Modification of Galactose Oxidase to Introduce Glucose 6-Oxidase Activity",
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    title = "Protein building blocks preserved by recombination",
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    title = "An Integrated Microfabricated Cell Sorter",
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    title = "Protein engineering of oxygenases for biocatalysis",
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    title = "A Colorimetric Assay to Quantify Dehydrogenase Activity in Crude Cell Lysates",
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    title = "Directed enzyme evolution",
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@article{https://resolver.caltech.edu/CaltechAUTHORS:20150619-100151141,
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    title = "Molecular and Ionic Recognition with Imprinted Polymers",
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