<h1 id="millard-and-muriel-jacobs-genetics-and-genomics-laboratory"><a href="./">Millard and Muriel Jacobs Genetics and Genomics Laboratory</a></h1> <h3 id="articles-from-caltechauthors">Articles from <a href="https://authors.library.caltech.edu">CaltechAUTHORS</a></h3> <ul> <li>Kitchen, Sheila A.; Naragon, Thomas H.; et al. (2024) <a href="https://authors.library.caltech.edu/records/8n92k-h7b39">The genomic and cellular basis of biosynthetic innovation in rove beetles</a>; Cell; Vol. 187; No. 14; 1-22; <a href="https://doi.org/10.1016/j.cell.2024.05.012">10.1016/j.cell.2024.05.012</a></li> <li>Duan, Mengtong; Dev, Ishaan; et al. (2024) <a href="https://authors.library.caltech.edu/records/xsahp-v8976">SEMPER: Stoichiometric expression of mRNA polycistrons by eukaryotic ribosomes for compact, ratio-tunable multi-gene expression</a>; Cell Systems; <a href="https://doi.org/10.1016/j.cels.2024.06.001">10.1016/j.cels.2024.06.001</a></li> <li>Chakrabarty, Yogaditya; Yang, Zheng; et al. (2024) <a href="https://authors.library.caltech.edu/records/brxbr-2nk64">The HRI branch of the integrated stress response selectively triggers mitophagy</a>; Molecular Cell; Vol. 84; No. 6; 1090-1100.e6; PMCID PMC11062084; <a href="https://doi.org/10.1016/j.molcel.2024.01.016">10.1016/j.molcel.2024.01.016</a></li> <li>Jacobs-Li, Jessica; Tang, Weiyi; et al. (2023) <a href="https://authors.library.caltech.edu/records/bpha3-br295">Single-cell profiling coupled with lineage analysis reveals vagal and sacral neural crest contributions to the developing enteric nervous system</a>; eLife; Vol. 12; e79156; PMCID PMC10627514; <a href="https://doi.org/10.7554/elife.79156">10.7554/elife.79156</a></li> <li>Shin, Boyoung; Zhou, Wen; et al. (2023) <a href="https://authors.library.caltech.edu/records/7x7jk-49y92">Runx factors launch T cell and innate lymphoid programs via direct and gene network-based mechanisms</a>; Nature Immunology; Vol. 24; No. 9; 1458-1472; PMCID PMC10673614; <a href="https://doi.org/10.1038/s41590-023-01585-z">10.1038/s41590-023-01585-z</a></li> <li>Stundl, Jan; Martik, Megan L.; et al. (2023) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20230725-49196000.18">Ancient vertebrate dermal armor evolved from trunk neural crest</a>; Proceedings of the National Academy of Sciences of the United States of America; Vol. 120; No. 30; e2221120120; PMCID PMC10372632; <a href="https://doi.org/10.1073/pnas.2221120120">10.1073/pnas.2221120120</a></li> <li>Chen, Xinhong; Wolfe, Damien A.; et al. (2023) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20230615-129198000.12">Functional gene delivery to and across brain vasculature of systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates</a>; Nature Communications; Vol. 14; Art. No. 3345; PMCID PMC10250345; <a href="https://doi.org/10.1038/s41467-023-38582-7">10.1038/s41467-023-38582-7</a></li> <li>Inglis, Alison J.; Guna, Alina; et al. (2023) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20230628-257040000.13">Coupled protein quality control during nonsense-mediated mRNA decay</a>; Journal of Cell Science; Vol. 136; No. 10; Art. No. jcs261216; PMCID PMC10234110; <a href="https://doi.org/10.1242/jcs.261216">10.1242/jcs.261216</a></li> <li>Chen, Peiwei and Aravin, Alexei A. (2023) <a href="https://authors.library.caltech.edu/records/m0g2n-4g932">Genetic control of a sex-specific piRNA program</a>; Current Biology; Vol. 33; No. 9; 1825-1835.e3; PMCID PMC10431932; <a href="https://doi.org/10.1016/j.cub.2023.03.057">10.1016/j.cub.2023.03.057</a></li> <li>Goronzy, Isabel N.; Quinodoz, Sofia A.; et al. (2022) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20230123-451320900.9">Simultaneous mapping of 3D structure and nascent RNAs argues against nuclear compartments that preclude transcription</a>; Cell Reports; Vol. 41; No. 9; Art. No. 111730; PMCID PMC9793828; <a href="https://doi.org/10.1016/j.celrep.2022.111730">10.1016/j.celrep.2022.111730</a></li> <li>Goertsen, David; Goeden, Nick; et al. (2022) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20220816-373601000">Targeting the lung epithelium after intravenous delivery by directed evolution of underexplored sites on the AAV capsid</a>; Molecular Therapy - Methods & Clinical Development; Vol. 26; 331-342; PMCID PMC9372736; <a href="https://doi.org/10.1016/j.omtm.2022.07.010">10.1016/j.omtm.2022.07.010</a></li> <li>Yang, Chien-I; Zhu, Zikun; et al. (2022) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20220816-373597000">System-wide analyses reveal essential roles of N-terminal protein modification in bacterial membrane integrity</a>; iScience; Vol. 25; No. 8; Art. No. 104756; PMCID PMC9356101; <a href="https://doi.org/10.1016/j.isci.2022.104756">10.1016/j.isci.2022.104756</a></li> <li>Galton, Riley; Fejes-Tóth, Katalin; et al. (2022) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20220811-456719000">Co-option of the piRNA pathway to regulate neural crest specification</a>; Science Advances; Vol. 8; No. 32; Art. No. abn1441; <a href="https://doi.org/10.1126/sciadv.abn1441">10.1126/sciadv.abn1441</a></li> <li>Yu, Hang; Speth, Daan R.; et al. (2022) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20220721-8119000">Community Structure and Microbial Associations in Sediment-Free Methanotrophic Enrichment Cultures from a Marine Methane Seep</a>; Applied and Environmental Microbiology; Vol. 88; No. 11; Art. No. e0210921; PMCID PMC9195934; <a href="https://doi.org/10.1128/aem.02109-21">10.1128/aem.02109-21</a></li> <li>Zhu, Zikun; Wang, Shuai; et al. (2022) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20220614-222089000">Ribosome profiling reveals multiple roles of SecA in cotranslational protein export</a>; Nature Communications; Vol. 13; Art. No. 3393; PMCID PMC9192764; <a href="https://doi.org/10.1038/s41467-022-31061-5">10.1038/s41467-022-31061-5</a></li> <li>Zhou, Wen; Gao, Fan; et al. (2022) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20220523-164956000">Single-cell deletion analyses show control of pro–T cell developmental speed and pathways by Tcf7, Spi1, Gata3, Bcl11a, Erg, and Bcl11b</a>; Science Immunology; Vol. 7; No. 71; eabm1920; PMCID PMC9273332; <a href="https://doi.org/10.1126/sciimmunol.abm1920">10.1126/sciimmunol.abm1920</a></li> <li>Ma, Yitong; Budde, Mark W.; et al. (2022) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20200909-145940519">Synthetic mammalian signaling circuits for robust cell population control</a>; Cell; Vol. 185; No. 6; 967-979; PMCID PMC8995209; <a href="https://doi.org/10.1016/j.cell.2022.01.026">10.1016/j.cell.2022.01.026</a></li> <li>Arrastia, Mary V.; Jachowicz, Joanna W.; et al. (2022) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20200813-130113364">Single-cell measurement of higher-order 3D genome organization with scSPRITE</a>; Nature Biotechnology; Vol. 40; No. 1; 64-73; <a href="https://doi.org/10.1038/s41587-021-00998-1">10.1038/s41587-021-00998-1</a></li> <li>Chen, Peiwei; Luo, Yicheng; et al. (2021) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20200826-094353695">RDC complex executes a dynamic piRNA program during Drosophila spermatogenesis to safeguard male fertility</a>; PLoS Genetics; Vol. 17; No. 9; Art. No. e1009591; PMCID PMC8412364; <a href="https://doi.org/10.1371/journal.pgen.1009591">10.1371/journal.pgen.1009591</a></li> <li>Buchman, Anna; Shriner, Isaiah; et al. (2021) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20200811-125007941">Engineered reproductively isolated species drive reversible population replacement</a>; Nature Communications; Vol. 12; Art. No. 3281; <a href="https://doi.org/10.1038/s41467-021-23531-z">10.1038/s41467-021-23531-z</a></li> <li>Chen, Peiwei; Kotov, Alexei A.; et al. (2021) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20200826-100150960">piRNA-mediated gene regulation and adaptation to sex-specific transposon expression in D. melanogaster male germline</a>; Genes and Development; Vol. 35; No. 11-12; 914-935; PMCID PMC8168559; <a href="https://doi.org/10.1101/gad.345041.120">10.1101/gad.345041.120</a></li> <li>Hutchins, Erica J.; Piacentino, Michael L.; et al. (2021) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20210302-141852646">Transcriptomic Identification of Draxin-Responsive Targets During Cranial Neural Crest EMT</a>; Frontiers in Physiology; Vol. 12; Art. No. 624037; PMCID PMC7886793; <a href="https://doi.org/10.3389/fphys.2021.624037">10.3389/fphys.2021.624037</a></li> <li>Finn, Paul B.; Bhimsaria, Devesh; et al. (2020) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20200818-152604358">Single position substitution of hairpin pyrrole-imidazole polyamides imparts distinct DNA-binding profiles across the human genome</a>; PLoS ONE; Vol. 15; No. 12; Art. No. e0243905; <a href="https://doi.org/10.1371/journal.pone.0243905">10.1371/journal.pone.0243905</a></li> <li>Sun, Simo; Shinya, Ryoji; et al. (2020) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20201022-112712963">Telomere-to-Telomere Genome Assembly of Bursaphelenchus okinawaensis Strain SH1</a>; Microbiology Resource Announcements; Vol. 9; No. 43; Art. No. e01000-20; PMCID PMC7585841; <a href="https://doi.org/10.1128/mra.01000-20">10.1128/mra.01000-20</a></li> <li>Khazaei, Tahmineh; Williams, Rory L.; et al. (2020) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20200813-144241318">Metabolic multistability and hysteresis in a model aerobe-anaerobe microbiome community</a>; Science Advances; Vol. 6; No. 33; Art. No. eaba0353; PMCID PMC7423363; <a href="https://doi.org/10.1126/sciadv.aba0353">10.1126/sciadv.aba0353</a></li> <li>Zhang, Yandong; Sohn, Changho; et al. (2020) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20200803-104852533">Detecting protein and post-translational modifications in single cells with iDentification and qUantification sEparaTion (DUET)</a>; Communications Biology; Vol. 3; Art. No. 420; <a href="https://doi.org/10.1038/s42003-020-01132-8">10.1038/s42003-020-01132-8</a></li> <li>Walton, Sophie J.; Wang, Han; et al. (2020) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20191028-093454817">Caenorhabditis elegans AF4/FMR2 Family Homolog affl-2 Regulates Heat-Shock-Induced Gene Expression</a>; Genetics; Vol. 215; No. 4; 1039-1054; PMCID PMC7404228; <a href="https://doi.org/10.1534/genetics.120.302923">10.1534/genetics.120.302923</a></li> <li>He, Peng; Williams, Brian A.; et al. (2020) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20200618-081148283">The changing mouse embryo transcriptome at whole tissue and single-cell resolution</a>; Nature; Vol. 583; No. 7818; 760-767; <a href="https://doi.org/10.1038/s41586-020-2536-x">10.1038/s41586-020-2536-x</a></li> <li>Koromila, Theodora; Gao, Fan; et al. (2020) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20191125-141648000">Odd-paired is a pioneer-like factor that coordinates with Zelda to control gene expression in embryos</a>; eLife; Vol. 9; Art. No. e59610; PMCID PMC7417190; <a href="https://doi.org/10.7554/eLife.59610">10.7554/eLife.59610</a></li> <li>Quintero-Cadena, Porfirio; Lenstra, Tineke L.; et al. (2020) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20191031-131636300">RNA Pol II Length and Disorder Enable Cooperative Scaling of Transcriptional Bursting</a>; Molecular Cell; Vol. 79; No. 2; 207-220; <a href="https://doi.org/10.1016/j.molcel.2020.05.030">10.1016/j.molcel.2020.05.030</a></li> <li>Yu, Hang and Leadbetter, Jared R. (2020) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20200408-160710037">Bacterial chemolithoautotrophy via manganese oxidation</a>; Nature; Vol. 583; No. 7816; 453-458; PMCID PMC7802741; <a href="https://doi.org/10.1038/s41586-020-2468-5">10.1038/s41586-020-2468-5</a></li> <li>Dalla Benetta, Elena; Antoshechkin, Igor; et al. (2020) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20191007-133644493">Genome Elimination Mediated by Gene Expression from a Selfish Chromosome</a>; Science Advances; Vol. 6; No. 14; Art. No. eaaz9808; PMCID PMC7124933; <a href="https://doi.org/10.1126/sciadv.aaz9808">10.1126/sciadv.aaz9808</a></li> <li>Gamez, Stephanie; Antoshechkin, Igor; et al. (2020) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20190904-144412708">The Developmental Transcriptome of Aedes albopictus, a Major Worldwide Human Disease Vector</a>; G3; Vol. 10; No. 3; 1051-1062; PMCID PMC7056973; <a href="https://doi.org/10.1534/g3.119.401006">10.1534/g3.119.401006</a></li> <li>Basta, David W.; Angeles-Albores, David; et al. (2020) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20200206-163326208">Heat-shock proteases promote survival of Pseudomonas aeruginosa during growth arrest</a>; Proceedings of the National Academy of Sciences of the United States of America; Vol. 117; No. 8; 4358-4367; PMCID PMC7049150; <a href="https://doi.org/10.1073/pnas.1912082117">10.1073/pnas.1912082117</a></li> <li>Tang, Weiyi; Martik, Megan L.; et al. (2019) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20190812-093416740">Cardiac neural crest contributes to cardiomyocytes in amniotes and heart regeneration in zebrafish</a>; eLife; Vol. 8; Art. No. e47929; PMCID PMC6721792; <a href="https://doi.org/10.7554/elife.47929">10.7554/elife.47929</a></li> <li>Perry, Elena K. and Newman, Dianne K. (2019) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20190419-100142089">The transcription factors ActR and SoxR differentially affect the phenazine tolerance of Agrobacterium tumefaciens</a>; Molecular Microbiology; Vol. 112; No. 1; 199-218; PMCID PMC6615960; <a href="https://doi.org/10.1111/mmi.14263">10.1111/mmi.14263</a></li> <li>Khazaei, Tahmineh; Barlow, Jacob T.; et al. (2018) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20180802-093834589">RNA markers enable phenotypic test of antibiotic susceptibility in Neisseria gonorrhoeae after 10 minutes of ciprofloxacin exposure</a>; Scientific Reports; Vol. 8; Art. No. 11606; PMCID PMC6072703; <a href="https://doi.org/10.1038/s41598-018-29707-w">10.1038/s41598-018-29707-w</a></li> <li>Kim, Jocelyn T.; Liu, Yarong; et al. (2017) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20170718-091900989">Dendritic cell–targeted lentiviral vector immunization uses pseudotransduction and DNA-mediated STING and cGAS activation</a>; Science Immunology; Vol. 2; No. 13; Art. No. eaal1329; PMCID PMC5845465; <a href="https://doi.org/10.1126/sciimmunol.aal1329">10.1126/sciimmunol.aal1329</a></li> <li>Seet, Christopher S.; He, Chongbin; et al. (2017) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20170124-111140333">Generation of mature T cells from human hematopoietic stem and progenitor cells in artificial thymic organoids</a>; Nature Methods; Vol. 14; No. 5; 521-530; PMCID PMC5426913; <a href="https://doi.org/10.1038/nmeth.4237">10.1038/nmeth.4237</a></li> <li>Nath, Ravi D.; Chow, Elly S.; et al. (2016) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20160818-085530875">C. elegans Stress-Induced Sleep Emerges from the Collective Action of Multiple Neuropeptides</a>; Current Biology; Vol. 26; No. 18; 2446-2455; PMCID PMC5694219; <a href="https://doi.org/10.1016/j.cub.2016.07.048">10.1016/j.cub.2016.07.048</a></li> <li>Babin, Brett M.; Bergkessel, Megan; et al. (2016) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20160120-081453238">SutA is a bacterial transcription factor expressed during slow growth in Pseudomonas aeruginosa</a>; Proceedings of the National Academy of Sciences of the United States of America; Vol. 113; No. 5; E597-E605; PMCID PMC4747698; <a href="https://doi.org/10.1073/pnas.1514412113">10.1073/pnas.1514412113</a></li> <li>Henley, Beverley M.; Williams, Brian A.; et al. (2013) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20130815-073947290">Transcriptional regulation by nicotine in dopaminergic neurons</a>; Biochemical Pharmacology; Vol. 86; No. 8; 1074-1083; PMCID PMC3969234; <a href="https://doi.org/10.1016/j.bcp.2013.07.031">10.1016/j.bcp.2013.07.031</a></li> <li>Akbari, Omar S.; Amrhein, Henry; et al. (2013) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20131003-143259486">The Developmental Transcriptome of the Mosquito Aedes aegypti, an Invasive Species and Major Arbovirus Vector</a>; G3; Vol. 3; No. 9; 1493-1509; PMCID PMC3755910; <a href="https://doi.org/10.1534/g3.113.006742">10.1534/g3.113.006742</a></li> <li>Zhang, Jingli A.; Mortazavi, Ali; et al. (2012) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20120511-113721604">Dynamic Transformations of Genome-wide Epigenetic Marking and Transcriptional Control Establish T Cell Identity</a>; Cell; Vol. 149; No. 2; 467-482; PMCID PMC3336965; <a href="https://doi.org/10.1016/j.cell.2012.01.056">10.1016/j.cell.2012.01.056</a></li> <li>Imoukhuede, P. I.; Moss, Fraser J.; et al. (2009) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20090903-090332845">Ezrin Mediates Tethering of the γ-Aminobutyric Acid Transporter GAT1 to Actin Filaments Via a C-Terminal PDZ-Interacting Domain</a>; Biophysical Journal; Vol. 96; No. 7; 2949-2960; PMCID PMC2711277; <a href="https://doi.org/10.1016/j.bpj.2008.11.070">10.1016/j.bpj.2008.11.070</a></li> <li>Hao, Shengli and Baltimore, David (2009) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20090413-083201541">The stability of mRNA influences the temporal order of the induction of genes encoding inflammatory molecules</a>; Nature Immunology; Vol. 10; No. 3; 281-288; PMCID PMC2775040; <a href="https://doi.org/10.1038/ni.1699">10.1038/ni.1699</a></li> <li>Vikalo, Haris; Hassibi, Babak; et al. (2008) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20090916-153943053">Modeling and Estimation for Real-Time Microarrays</a>; IEEE Journal of Selected Topics in Signal Processing; Vol. 2; No. 3; 286-296; <a href="https://doi.org/10.1109/JSTSP.2008.924383">10.1109/JSTSP.2008.924383</a></li> <li>O’Connell, Ryan M.; Rao, Dinesh S.; et al. (2008) <a href="https://resolver.caltech.edu/CaltechAUTHORS:OCOjem08">Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder</a>; Journal of Experimental Medicine; Vol. 205; No. 3; 585-594; PMCID PMC2275382; <a href="https://doi.org/10.1084/jem.20072108">10.1084/jem.20072108</a></li> <li>Kannangara, Rubini; Branigan, Caroline; et al. (2007) <a href="https://resolver.caltech.edu/CaltechAUTHORS:20170408-172815604">The Transcription Factor WIN1/SHN1 Regulates Cutin Biosynthesis in Arabidopsis thaliana</a>; Plant Cell; Vol. 19; No. 4; 1278-1294; PMCID PMC1913754; <a href="https://doi.org/10.1105/tpc.106.047076">10.1105/tpc.106.047076</a></li> <li>O’Connell, Ryan M.; Taganov, Konstantin D.; et al. (2007) <a href="https://resolver.caltech.edu/CaltechAUTHORS:OCOpnas07">MicroRNA-155 is induced during the macrophage inflammatory response</a>; Proceedings of the National Academy of Sciences of the United States of America; Vol. 105; No. 5; 1604-1609; PMCID PMC1780072; <a href="https://doi.org/10.1073/pnas.0610731104">10.1073/pnas.0610731104</a></li> <li>Taganov, Konstantin D.; Boldin, Mark P.; et al. 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